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Topic:Horse Racing

Horse racing is a competitive equestrian sport involving horses ridden by jockeys over set distances, often on flat tracks or over obstacles. It is characterized by a variety of race types, including thoroughbred, harness, and steeplechase, each with distinct rules and traditions. The sport emphasizes speed, stamina, and strategy, with races typically categorized by distance, surface type, and horse age or breed. Horse racing plays a significant role in the equine industry, influencing breeding, training, and veterinary care practices. This page compiles peer-reviewed research studies and scholarly articles that explore the physiological demands, training methodologies, and health considerations associated with horse racing.
Letter to the Editor: Validation of standing cone beam computed tomography for diagnosing subchondral fetlock pathology in the Thoroughbred racehorse.
Equine veterinary journal    April 10, 2021   Volume 53, Issue 3 628-629 doi: 10.1111/evj.13433
Ramzan PHL.No abstract available
Response to Letter to the Editor: Validation of standing cone beam computed tomography for diagnosing subchondral fetlock pathology in the Thoroughbred racehorse.
Equine veterinary journal    April 10, 2021   Volume 53, Issue 3 630-631 doi: 10.1111/evj.13441
Wulster K, Ortved K, Curtiss A, Richardson D.No abstract available
Equine respiratory viruses, airway inflammation and performance in thoroughbred racehorses.
Veterinary microbiology    April 10, 2021   Volume 257 109070 doi: 10.1016/j.vetmic.2021.109070
Couetil L, Ivester K, Barnum S, Pusterla N.Equine asthma is a common cause of poor performance in racehorses but it is unclear if respiratory viruses contribute to its etiology. The objective of the study was to determine if respiratory viruses were associated with clinical signs and bronchoalveolar lavage fluid (BALF) cytology in Thoroughbred racehorses. Equine herpesviruses (EHV-1, 2, 4, 5) and equine rhinitis A and B viruses (ERBV, ERAV) genomes were quantified by qPCR in nasopharyngeal, tracheal, and BALF samples collected after racing. The relationships between virus detection and load and clinical signs, performance, BALF cytolog...
Antimicrobial Resistance and Extended-Spectrum Beta-Lactamase (ESBL) Genes in E. coli Isolated from Equine Fecal Samples in Turkey.
Journal of equine veterinary science    April 6, 2021   Volume 101 103461 doi: 10.1016/j.jevs.2021.103461
Yiğin A.The extensive use of antibacterial agents used for treatment in human and veterinary clinics to increase yield in livestock and aquaculture in developing countries causes the detection and spread of multidrug-resistant (MDR) strains in different sources. The presence of Escherichia coli strains is very common in racehorses and it's a serious problem on horse farms. Extended-spectrum beta-lactamase (ESBL) production is an important source of MDR development in Gram-negative strains such as E.coli. This study aimed to detect the presence of ESBL genes in E. coli strains isolated from horse farms...
Factors Associated with Mortality in Ontario Standardbred Racing: 2003-2015.
Animals : an open access journal from MDPI    April 5, 2021   Volume 11, Issue 4 1028 doi: 10.3390/ani11041028
Physick-Sheard P, Avison A, Sears W.Factors associated with mortality in standardbred racehorses were assessed through a retrospective annualized cohort study of all-cause mortality from 2003-2015 ( = 978) (identified in the Ontario Racehorse Death Registry). Race and qualifying data for official work-events were also gathered (1,778,330 work-events, 125,200 horse years). Multivariable logistic regression analysis revealed sex, age, and indices of workload and intensity and their interactions to be strongly associated with mortality. Track class, race versus qualifying performance, and work-event outcome (finish position, scratc...
Speed and Blood Parameters Differ between Arabian and Žemaitukai Horses during Endurance Racing.
Animals : an open access journal from MDPI    April 1, 2021   Volume 11, Issue 4 995 doi: 10.3390/ani11040995
Poškienė I, Gruodytė R, Autukaitė J, Juozaitienė V, Antanaitis R.Fédération Equestre Internationale (FEI) has described equine endurance racing as the second largest discipline in the world, above which is only show jumping. The Žemaitukai is an ancient indigenous Lithuanian horse breed known since the 6th or 7th century. The Arabian horse breed is one of the oldest human-developed horse breeds in the world. Compared with other race horse breeds, the muscle tissue of Arabian horses is characterized by significant differences in structure-a predominance of oxidative fiber type I is observed in Arabians, making them the prevailing breed in endurance racing...
Polymorphisms at Myostatin Gene (MSTN) and the Associations with Sport Performances in Anglo-Arabian Racehorses.
Animals : an open access journal from MDPI    March 30, 2021   Volume 11, Issue 4 doi: 10.3390/ani11040964
Pira E, Vacca GM, Dettori ML, Piras G, Moro M, Paschino P, Pazzola M.One hundred and eighty Anglo-Arabian horses running 1239 races were sampled for the present study. DNA was extracted from the blood and myostatin gene, MSTN, was genotyped. Moreover, prizes won and places were achieved for the 1239 races to perform association analyses between the different genotypes and sport traits. Two SNPs already reported in previous studies regarding the Thoroughbred breed, rs69472472 and rs397152648, were revealed as polymorphic. The linkage disequilibrium analysis investigating the haplotype structure of MSTN did not evidence any association block. Polymorphism at SNP ...
A Prospective Study of Training Methods for Two-Year-Old Thoroughbred Racehorses in Queensland, Australia, and Analysis of the Differences in Training Methods between Trainers of Varying Stable Sizes.
Animals : an open access journal from MDPI    March 25, 2021   Volume 11, Issue 4 928 doi: 10.3390/ani11040928
Crawford KL, Finnane A, Greer RM, Phillips CJC, Bishop EL, Woldeyohannes SM, Perkins NR, Ahern BJ.Worldwide, musculoskeletal injuries remain a major problem for the Thoroughbred racing industry. There is a strong interest in developing training and management strategies to reduce the impact of musculoskeletal injuries, however, progress has been limited by studies reporting conflicting findings, and a limited understanding of the role of different training methods in preventing injury. There is little data on patterns of rest periods and exercise data and how these vary between trainers. This prospective study of two-year-old racehorses was conducted in Queensland, Australia and involved w...
The race that segments a nation: Findings from a convenience poll of attitudes toward the Melbourne Cup Thoroughbred horse race, gambling and animal cruelty.
PloS one    March 24, 2021   Volume 16, Issue 3 e0248945 doi: 10.1371/journal.pone.0248945
Wilson BJ, Thompson KR, McGreevy PD.The annual Melbourne Cup Thoroughbred horse race has iconic status among many Australians but sits in the context of increasing criticism of the welfare of Thoroughbred racing horses and the ethics of gambling. Despite heated debates and protests playing out in the public domain, there is scant empirical research to document Australian attitudes to the Melbourne Cup, or horse racing more generally. Specifically, little is known about how support for or against the Melbourne Cup correlate with age, gender, income and level of education. To provide a more nuanced understanding of attitudes towar...
Effects of Fatigue on Stride Parameters in Thoroughbred Racehorses During Races.
Journal of equine veterinary science    March 16, 2021   Volume 101 103447 doi: 10.1016/j.jevs.2021.103447
Takahashi Y, Takahashi T, Mukai K, Ohmura H.Exercise intensity during races is considerably high. To understand how Thoroughbreds adapt to fatigue conditions, stride parameters for the first and second lap of the race (2400-m, turf) were compared. A high-speed video system was set in a right lateral position about 20 m before the finishing post, with a field view width of about 16 m. The stride frequency, the length between each limb (hind step, diagonal step, fore step, and airborne step), and stride length were measured and analyzed using a generalized linear mixed model. Compared with the first lap, the mean ± standard deviation val...
Dust exposure and pulmonary inflammation in Standardbred racehorses fed dry hay or haylage: A pilot study.
Veterinary journal (London, England : 1997)    March 13, 2021   Volume 271 105654 doi: 10.1016/j.tvjl.2021.105654
Olave CJ, Ivester KM, Couetil LL, Kritchevsky JE, Tinkler SH, Mukhopadhyay A.Respirable dust exposure is linked to airway inflammation in racehorses. Feeding haylage may reduce dust exposure by 60-70%. The objective of this study was to compare dust exposure, airway cytology, and inflammatory cytokine concentrations between horses fed haylage or hay over 6 weeks while in training. Seven healthy Standardbred horses were randomly assigned to be fed alfalfa hay (n = 3) or grass-alfalfa mix haylage (n = 4) for six weeks while training on a treadmill. Dust exposure was measured gravimetrically at the breathing zone. Endotoxin and β-glucan concentrations in respirable dust ...
Use of high resolution/accurate mass full scan/data-dependent acquisition for targeted/non-targeted screening in equine doping control.
Analytical methods : advancing methods and applications    March 12, 2021   Volume 13, Issue 13 1565-1575 doi: 10.1039/d0ay02297g
You Y, Proctor RM, Guo K, Li X, Xue E, Guan F, Robinson MA.High-resolution mass spectrometry (HRMS) is a very powerful technology for equine doping control analysis. The more recently developed hybrid type of Orbitrap-based HRMS instrument allows for both targeted and non-targeted screening analyses in a single liquid chromatography-high resolution tandem mass spectrometry (LC-HRMS/MS) run. In the present study, an LC-HRMS/MS method was developed and validated to detect prohibited substances in equine sports. The substances were recovered from equine plasma by liquid-liquid extraction (LLE) using methyl tert-butyl ether and were separated on a C18 rev...
Investigating the pathogenesis of high-serum gamma-glutamyl transferase activity in Thoroughbred racehorses: A series of case-control studies.
Equine veterinary journal    March 8, 2021   Volume 54, Issue 1 39-51 doi: 10.1111/evj.13435
Mann S, Ramsay JD, Wakshlag JJ, Stokol T, Reed S, Divers TJ.High-serum γ-Glutamyl Transferase (GGT) activity has been associated with and thought to be a marker of maladaptation to training and possibly poor performance in racehorses, but the cause is unknown. Objective: To investigate possible metabolic and infectious causes for the high GGT syndrome. Methods: Pilot case-control study and nested case-control study. Methods: The case-control study in 2017 included 16 horses (8 cases and 8 controls with median [range] serum GGT 82 [74-148] and 22 [19-28] IU/L, respectively) from the same stable. In 2018, similar testing was performed in a nested case-...
Evaluation of Treatment With Respiratory Gene Technology and Serum in a Group of Standard Bred Racehorses With Cytological Evidence of Mild Equine Asthma.
Journal of equine veterinary science    March 8, 2021   Volume 101 103435 doi: 10.1016/j.jevs.2021.103435
Hansen S, Laustsen L, Otten ND, Skovgaard K, Bech R, Byrgesen S, Hopster-Iversen C, Fjeldborg J.Alternative treatment options to glucocorticoids for equine asthma is desirable due to withdrawal time. The objective was to evaluate if serum and Respiratory Gene Technology (RGT), a commercial kit to produce autologous conditioned serum, was effective in reducing bronchoalveolar lavage (BAL) neutrophils and mast cells in racehorses with cytological evidence of mild equine asthma . Thirty-six Standardbred trotters in active training were enrolled in this randomized clinical trial; a healthy control group (n=11), a RGT group (n=12) and a serum group (n=13). Endoscopy including tracheal wash (T...
Effects of a nutraceutical supplement on gastrointestinal health in racing standardbreds.
Journal of animal physiology and animal nutrition    March 6, 2021   Volume 105, Issue 3 558-568 doi: 10.1111/jpn.13508
Wellard L, Medyk K, Pearson W.Feed additives that accelerate gastrointestinal transit time may help support normal gastrointestinal function in horses at risk for impaction colic. Previous research has demonstrated significant stimulatory effect of a hemp-based nutraceutical product (Gs Formula; GF) on contractility of gastric smooth muscle and gastrin production in vitro. Objective: To quantify effects of GF on indicators of GIT transit time and tight junction proteins. Methods: Randomized placebo-controlled cross-over study. Methods: Eight Standardbreds were administered 200 plastic beads by nasogastric tube before (base...
Is it ethical to continue to race horses?
The Veterinary record    February 28, 2021   Volume 187, Issue 1 38 doi: 10.1136/vr.m2778
Williams D.No abstract available
The Reported Use of Tongue-Ties and Nosebands in Thoroughbred and Standardbred Horse Racing-A Pilot Study.
Animals : an open access journal from MDPI    February 26, 2021   Volume 11, Issue 3 doi: 10.3390/ani11030622
Weller D, Franklin S, White P, Shea G, Fenner K, Wilson B, Wilkins C, McGreevy P.This article reports on the results of a survey of racehorse trainers (n = 112) outlining the reasons for tongue-tie (TT) and noseband (NB) use by Thoroughbred trainers (TBTs) (n = 72) and Standardbred trainers (SBTs) (n = 40). The study also investigated the reported effectiveness of TTs and possible complications arising from their use. Tongue-tie use was reported by 62.5% (n = 70) of racehorse trainers. The reasons for TT use varied between TBTs and SBTs. For TBTs, the most common reason for TT use was to prevent or reduce airway obstruction (72.3%, n = 34), followed closely by to prevent o...
Effect of racing on cardiac troponin I concentration and associations with cardiac rhythm disturbances in Standardbred racehorses.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    February 24, 2021   Volume 35 14-24 doi: 10.1016/j.jvc.2021.02.002
Rossi TM, Kavsak PA, Maxie MG, Pearl DL, Pyle WG, Physick-Sheard PW.Accumulating evidence indicates intense exercise can be associated with myocardial damage. Investigating the impact of maximal effort on myocardium and exploring possible association of injury with rhythm disturbance requires a high-sensitivity cardiac troponin assay. The objectives of this study were: (1) to determine the effect of racing on serum cardiac troponin I (cTnI) in Standardbred horses using a high-sensitivity assay; (2) to determine the 99th percentile of cTnI in healthy horses and investigate the effect of demographic variables on cTnI prevailing pre-race in Standardbred horses us...
Racehorse Trainer Mental Health: Prevalence and Risk Factors.
Journal of equine veterinary science    February 21, 2021   Volume 101 103423 doi: 10.1016/j.jevs.2021.103423
King L, Cullen SJ, O'Connor S, McGoldrick A, Pugh J, Warrington G, Losty C.Racehorse trainers play an important role within the horseracing industry. Despite this, scarce empirical information exists regarding the mental health of this population. Thus, the purpose of the present study was to explore the prevalence of symptoms related to common mental disorders (CMDs) and their associations with specific risk factors for CMD. Participants completed an anonymous online questionnaire. CMDs were assessed including distress, depression, generalized anxiety and adverse alcohol use. The risk factors examined included career dissatisfaction, social support and financial dif...
Incidence, recurrence, and outcome of postrace atrial fibrillation in Thoroughbred horses.
Journal of veterinary internal medicine    February 19, 2021   Volume 35, Issue 2 1111-1120 doi: 10.1111/jvim.16063
Nath LC, Elliott AD, Weir J, Curl P, Rosanowski SM, Franklin S.Atrial fibrillation (AF) impacts performance and horse and jockey safety. Understanding the outcomes of AF identified postrace will better inform regulatory policy. Objective: To investigate the outcomes after episodes of AF identified postrace and determine whether affected horses are at increased risk of additional episodes compared to the general racing population. Methods: Total of 4684 Thoroughbred racehorses. Methods: Race records for Thoroughbred horses racing in Hong Kong from 2007 to 2017 were reviewed. Horses that performed below expectation were examined by cardiac auscultation and ...
Stress fracture of the palmar, distal cortex of the third metacarpal bone: A diagnostic challenge with a good prognosis.
Equine veterinary journal    February 17, 2021   Volume 54, Issue 1 74-81 doi: 10.1111/evj.13426
Shan R, Johnston AS, Rosanowski SM, O'Shea J, Riggs CM.Transverse stress fracture of the palmar cortex of the distal aspect of the third metacarpal bone (TSF PCD McIII) is poorly documented. Objective: To describe the typical signalment of this injury, the common clinical and radiological signs and prognosis. Methods: A retrospective hospital-based case series with follow-up of racing records. Methods: All cases of TSF PCD McIII diagnosed among racehorses in training at the Hong Kong Jockey Club between 2011 and 2019 were identified. Clinical records were reviewed and documented signs were recorded for each case. Findings from a predefined list of...
Real-time three-dimensional echocardiography for left atrial volume assessment in Thoroughbred racehorses: Observer variability and comparison with two-dimensional echocardiography.
Equine veterinary journal    February 15, 2021   Volume 54, Issue 1 176-190 doi: 10.1111/evj.13408
Worsman FCF, Miller ZJ, Shaw DJ, Blissitt KJ, Keen JA.Left atrial size predicts cardiac morbidity and mortality in humans and dogs. Real-time three-dimensional echocardiography (3DE) may be reliable for assessing left atrial volume (LAV) in horses. Objective: To determine intra- and interobserver variability estimates of 3DE-LAV and compare it to that of 2DE-LAV estimates. Methods: Method comparison. Methods: 3DE datasets were obtained from 40 horses, then graded for quality, creating a final study population of 22 horses. The 3DE and 2DE maximum LAV (LAV ) and minimum LAV (LAV ) were measured, and left atrial emptying volume (LA EV) and left atr...
Expression of select mRNA in Thoroughbreds with catastrophic racing injuries.
Equine veterinary journal    February 15, 2021   Volume 54, Issue 1 63-73 doi: 10.1111/evj.13423
Page AE, Adam E, Arthur R, Barker V, Franklin F, Friedman R, Grande T, Hardy M, Howard B, Partridge E, Rutledge M, Scollay M, Stewart JC, Vale A....The ability to identify horses at risk for catastrophic injuries continues to be a pressing issue for the racing industry, especially given recent events in North America. Objective: Since most catastrophic injuries occur in areas of existing pathology and this pathology is likely to elicit an inflammatory response, it was hypothesised that analysis of messenger RNA (mRNA) expression would detect significant changes in select genes in horses at risk for a catastrophic injury. Methods: Prospective cohort study. Methods: Five racing jurisdictions across the United States participated in this stu...
Comprehensive characterization of the peroxisome proliferator activated receptor-δ agonist GW501516 for horse doping control analysis.
Drug testing and analysis    February 11, 2021   Volume 13, Issue 6 1191-1202 doi: 10.1002/dta.3013
Trevisiol S, Moulard Y, Delcourt V, Jaubert M, Boyer S, Tendon S, Haryouli H, Taleb W, Caroff M, Chabot B, Drif L, André F, Garcia P, Loup B....According to international sport institutions, the use of peroxisome proliferator activated receptor (PPAR)-δ agonists is forbidden at any time in athlete career due to their capabilities to increase physical and endurance performances. The (PPAR)-δ agonist GW501516 is prohibited for sale but is easily available on internet and can be used by cheaters. In the context of doping control, urine is the preferred matrix because of the non-invasive nature of sampling and providing broader exposure detection times to forbidden molecules but often not detected under its native form due to the organi...
Pathways of calcium regulation, electron transport, and mitochondrial protein translation are molecular signatures of susceptibility to recurrent exertional rhabdomyolysis in Thoroughbred racehorses.
PloS one    February 10, 2021   Volume 16, Issue 2 e0244556 doi: 10.1371/journal.pone.0244556
Aldrich K, Velez-Irizarry D, Fenger C, Schott M, Valberg SJ.Recurrent exertional rhabdomyolysis (RER) is a chronic muscle disorder of unknown etiology in racehorses. A potential role of intramuscular calcium (Ca2+) dysregulation in RER has led to the use of dantrolene to prevent episodes of rhabdomyolysis. We examined differentially expressed proteins (DEP) and gene transcripts (DEG) in gluteal muscle of Thoroughbred race-trained mares after exercise among three groups of 5 horses each; 1) horses susceptible to, but not currently experiencing rhabdomyolysis, 2) healthy horses with no history of RER (control), 3) RER-susceptible horses treated with dant...
Training Young Horses: The Science behind the Benefits.
Animals : an open access journal from MDPI    February 9, 2021   Volume 11, Issue 2 463 doi: 10.3390/ani11020463
Logan AA, Nielsen BD.Conflicting research and anecdotal evidence have created disagreement among equestrians as to whether two-year-old horses should be trained and raced. The objective of this literature review is to evaluate epidemiological studies, as well as physiological data on equine bone, articular cartilage, and tendons to better determine the impact of training and racing two-year-old horses. The evaluation of numerous studies on the topic provides evidence that a horse which is trained or raced as a two-year-old has a lower risk of injury and better adapted tissues for the rigors of racing. Unfortunatel...
A validated method for the quantification of IOX-2, a potent prolyl hydroxylase inhibitor in equine urine and plasma using liquid chromatography-high-resolution mass spectrometry.
Drug testing and analysis    February 6, 2021   Volume 13, Issue 6 1178-1190 doi: 10.1002/dta.3010
Mikhail E, Siccardi E, Bawazir A, Rajesh A, Prathyush S, Al Wazani DMK, Sabeek M, John T.IOX-2 is a potent inhibitor of enzyme prolyl hydroxylases-2 (PHD) that plays a critical role in regulating hypoxia inducible factor (HIF) abundance and oxygen homeostasis. Federation for Equestrian Sports has listed HIF activators as prohibited substances to prevent their usage in doping. Consequently, it became essential to develop adequate knowledge and testing methods to detect it in equine sports drug testing samples. The validated method utilizes ultra-high-performance liquid chromatography coupled to high-resolution mass spectrometry in order to detect extremely low concentration of the ...
Kavain detection in post-race equine urine sample: A case report.
Drug testing and analysis    January 26, 2021   Volume 13, Issue 4 883-886 doi: 10.1002/dta.2996
Barnabé A, Moulard Y, Trevisiol S, Boyer S, Caroff M, Taleb W, Tendon S, Drif L, Delcourt V, Popot MA, Bailly-Chouriberry L.The study focuses on the discovery of kavain, a natural-occurring compound of the plant Piper methysticum, in a post-race urine sample of a horse. The researchers traced the potential source […]
Effect of Intense Exercise on the Level of Bacteroidetes and Firmicutes Phyla in the Digestive System of Thoroughbred Racehorses.
Animals : an open access journal from MDPI    January 24, 2021   Volume 11, Issue 2 290 doi: 10.3390/ani11020290
Górniak W, Cholewińska P, Szeligowska N, Wołoszyńska M, Soroko M, Czyż K.Exercise significantly affects the body of both animals and humans, including the composition of the digestive microbiome. This study aimed to determine the changes in the composition of the most numerous bacterial phyla (Firmicutes and Bacteroidetes, as well as the level of the family) in the digestive system of horses under the influence of physical effort. The study included a group of 17 Thoroughbred racehorses at the age of 3 years, fed the same forage, from whom feces samples were collected individually before and 48 h after physical effort. The obtained samples were subjected to DNA is...
Detection and longitudinal distribution of GW1516 and its metabolites in equine hair for doping control using liquid chromatography/high-resolution mass spectrometry.
Rapid communications in mass spectrometry : RCM    January 21, 2021   Volume 35, Issue 8 e9050 doi: 10.1002/rcm.9050
Ishii H, Shibuya M, Leung GN, Nozawa S, Yamashita S, Yamada M, Kushiro A, Kasashima Y, Okada J, Kawasaki K, Kijima-Suda I.GW1516 is a peroxisome proliferator-activated receptor-δ (PPAR-δ) agonist that is banned in horseracing and equestrian sports. Long-term detection and longitudinal distribution of GW1516 in the mane of a horse are reported for the first time and this hair analysis could prolong the detection window of GW1516 for doping control. Methods: Mane hairs were divided into three segments (0-7, 7-15, and >15 cm from the cut end) and completely pulverized and homogenized for analysis. The pulverized hair samples were extracted with methanol followed by further purification and the extracts were a...
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