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Topic:Horses
"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Empyema of the equine paranasal sinuses. A survey of 28 cases of chronic purulent infection of the sinuses in the horse showed a relationship between incidence and age, and a probable relationship with breed. Dental disease was apparently the cause of half the cases. The conventional treatment of trephination followed by irrigation with antiseptic solutions resulted in freedom from recurrence of the disease for over 1 year in 17 of the 28 horses. Antibiotic therapy appears to be useless in chronic empyema. The prognosis is adversely affected by the development of facial swelling, a sign seen usually only in long-standing cases.
An expansion and compression technique for reducing and stabilizing proximal epiphyseal fractures of the tibia in foals. Proximal tibial epiphyseal fractures in 2 foals were reduced and stabilized by expansion and compression between 2 transversely placed Steinman pins, one on each side of the fracture. A Charnley apparatus or turnbuckles placed between the pins on each side of the fracture provided the mechanical advantage for repositioning the fracture fragments and achieving rigid fixation during healing. A light cast was applied over the fixation apparatus, keeping the limb in an extended position. The cast and fixation apparatus were removed after 4 weeks. The technique allowed rapid healing and adequate am...
Plasma concentrations, plasma protein binding and residues of sulfamonomethoxine in pigs, horses and cattle. The protein binding, the plasma half-life and the residue depletion of sulfamonomethoxine (SMM) after intramuscular administration were investigated in pigs, horses and cattle. Protein binding was weakly concentration-dependent. The bound fraction in plasma in the therapeutic range amounted to approximately 45, 40 and 50% for pigs, horses and cattle respectively, and the plasma half-lives were approximately 5.1, 5.7 and 3.1 hours respectively. SMM levels were less than 1 mug/g in muscle tissue after 36, 20 and 12 hours in pigs, horses and cattle respectively. In the kidney SMM levels were not ...
Isolation and partial characterization of the major glycoproteins of horse and swine erythrocyte membranes. The major glycoproteins of horse and swine erythrocyte membranes were isolated and examined chemically and immunologically. The major glycoprotein of horse erythrocyte membranes had a molecular weight of 33 000 and consisted of 46.2% protein and 53.8% carbohydrate, of which 9.4% was hexose, 10.1% hexosamine and 33.7% sialic acid. This glycoprotein was associated with activity for the infectious mononucleosis heterophile antigen. There were two different major glycoproteins in swine erythrocyte membranes. One major glycoprotein had a molecular weight of 46 200 and consisted of 34.2% protein and...
Urinary oestrogen and plasma progesterone levels in non-pregnant mares. Eight mares were observed clinically for 14 months to detect oestrus and ovarian activity, and assays of urinary oestrogens and plasma progesterone were performed. Cyclical ovarian activity occurred during 60% of the experimental period. Persistent luteal activity was found over 20% of the period and for the rest of the time activity was absent. Cyclical activity was characterized by the alternation of periods of low and high progesterone levels corresponding to the follicular and luteal phases of the ovarian cycle. During the follicular phase, urinary oestrogen levels increased to a maximum o...
Influence of intrauterine saline infusion upon the oestrous cycle of the mare. The effect of intrauterine saline on reproductive function was studied by infusion of mares in anoestrus, dioestrus, oestrus and prolonged dioestrus. Anoestrous mares were unaffected except near the beginning and end of the breeding season when anovulatory heats were induced. Dioestrous mares infused between Days 5 and 9 returned to heat an average of 3-8 days earlier than expected, and infusions during dioestrus were followed by ovulatory heats of normal fertility. Three mares in prolonged dioestrus showed ovulatory heats within 3 to 9 days of infusion. Infusions during oestrus had no appreci...
A review of cytogenetics in equine reproduction. The karyotype of the horse consists of 64 chromosomes; 18 pairs have a terminal centromere and 13 pairs a non-terminal centromere. Identification of individual chromosomes is enhanced by the use of band-staining techniques which allow recognition of minor structural rearrangements of chromatin material. Seven previously reported cases of male pseudohermaphroditism with chromosome studies are reviewed. Three were genetic females, one was basically an XX/XY chimaera, one was an XX/XXY chimaera, and one was an XXXY. Also reviewed is an infertile mare with 63 chromosomes and no distinguishable sex...
A histochemical study of steroid metabolism in the equine fetus and placenta. The distribution of several hydroxysteroid dehydrogenases (HSD) was examined in a variety of equine placental and fetal tissues. The main points of interest were: (a) the lack of dehydrogenase activity in the gonad, (b) the appearance of a variety of HSDs in the trophoblast as early as 13 days of gestation, (c) the histochemical similarity between the cells of the trophoblast and the endometrial cup, and (d) the restriction of the strong endometrial 17beta-HSD reaction to those parts of the uterine epithelium directly apposed to the trophoblast.
Survey of reproductive efficiency in the Quarter-horse and Thoroughbred. Reproductive efficiency was evaluated for 838 Quarter-horse mare-years on five farms and 939 Thoroughbred mare-years on seven farms over 4 years. The pregnancy rate from first service was 51% for Quarter-horse mares and 43% for Thoroughbred mares (P less than 0-05). The cumulative pregnancy rate after five services was 85% for Quarter-horse and 77% for Thoroughbred mares (P less than 0-05). First-service-period pregnancy rates were 44, 40 and 54% for maiden, barren and foaling mares, respectively. Cumulative pregnancy rates after five service-periods were 84, 74 and 84% for maiden, barren and ...
A survey of eggs in the oviducts of mares. A total of 424 eggs was recovered from flushings of 176 pairs of oviducts. Of these eggs, 324 were in a state of advanced degeneration (Type 4) and ten appeared to have been recently ovulated (Type 1). The number of eggs/oviduct varied from 0 to 13, most being up to 3 eggs, but fifty oviducts contained no eggs. It is widely believed that unfertilized ova are selectively retained in the oviducts but an alternative explanation for their presence is put forward.
Germ cell development and the meiotic prophase in the fetal horse ovary. A histological study of the developing germinal epithelium in the fetal horse ovary shows an enormous wastage of oocytes during the meiotic phase, between Days 73 and 150 of pregnancy. The first groups of oocytes to enter this phage undergo mass degeneration and eventually disappear; few, if any, oocytes develop to primordial follicles. Peripheral oogonia, dividing by mitosis, give rise to more oocytes which pass through the same changes and are also reduced by degeneration, but by Day 150 primordial follicles are fairly common.
Ontogeny of equine haemoglobins. Studies were made of the O2 affinities of fetal and maternal haemoglobins in the horse, and correlations were found with erythrocytic levels of 2,3-diphosphoglycerate.
Experimental studies on equine herpesvirus type 1 infections. The EHV-1 viruses of fetal origin grew better and had a wider tissue culture host range than those isolated from horses with respiratory diseases. Comparisons of a fetal isolate (F/304) and a respiratory disease isolate (R/NM-3) in partly immune horses showed that the F/304 virus infected horses more readily, grew better in the nasopharynx, was more likely to cause abortion, and was excreted to a greater extent into the environment.
The gnotobiotic foal in the study of infectious diseases. A method of rearing germ-free gnotobiotic foals is described. To date, four foals have been infected with rhinopneumonitis and the only clinical signs of infection have been a transient fever and leukopaenia; no detailed results are, as yet, available.
Surgical and non-surgical egg transfer in horses. Surgical and non-surgical methods used for the recovery and transfer of fertilized horse eggs are described. Sixteen of the twenty-three zygotes recovered surgically between Days 1 to 6 after ovulation from thirty donor mares were transferred surgically to synchronized recipients; seven pregnancies resulted. Seven of the eleven zygotes recovered non-surgically between Days 6 to 8 after ovulation from twenty-eight donor mares were transferred non-surgically to synchronized recipients; five pregnancies resulted.
Comparison of the methods of rectal palpation and haemagglutination-inhibition assay for diagnosis of pregnancy in mares. The diagnostic value of rectal palpation and immunological assay of PMSG was tested at different stages of pregnancy in mares inseminated with frozen semen in three separate studies. The results were based on foaling success and particular attention was paid to the numbers of inconsistent results obtained by the two tests. Generally, the number of false positive diagnoses was lower for the immunological assay than for palpation in early pregnancy (Days 40 to 60) and the relationship became reversed later in gestation.
Abnormalities of mating behaviour in domestic stallions. Experimental and clinical observations were made to treat abnormal sexual behaviour. The most common cause of abnormality was mismanagement of the animal; over-use and rough treatment at service and too-frequent ejaculation during winter had a detrimental effect on the behaviour of young stallions. Pain due to injury incurred at copulation or when associated with mounting attempts was also a common cause of impotence. Most impotent stallions responded well to re-training and recovery can be achieved without pharmacological treatment in most cases.
Chromosome abnormalities as a cause of infertility in mares. Chromosomal abnormalities have been detected in seven mares isolated by their poor reproductive performance. All had small or rudimentary gonads and absent or irregular oestrous cycles. Two mares had an XO genotype, one was a 65,XXX female and another a 64,XY sex-reversed female. Two other mares were sex chromosome mosaics of the 63,X/64,XX type. The seventh mare showed a normal female karyotype but a small extra autosomal fragment was found in a few cells.
Transfer of gases and metabolites in the equine placenta: a comparison with other species. Mares and fetuses with indwelling catheters in the umbilical and uterine vessels have been used to monitor transplacental blood gas tensions, pH, O2 affinities and the concentration of various metabolites in fetal and maternal blood during late gestation. Measurements of umbilical and uterine blood flows and arterio-venous differences enabled the uptake of O2 and glucose by the fetus and the uterus to be estimated. The present findings are compared with those from other species in comparable conditions.
Effects of prostaglandin F2alpha on the oestrous cycle and pregnancy in mares. Several experiments indicated that prostaglandin F2alpha (PGF2alpha) has luteolytic and abortifacient properties in mares. A single subcutaneous injection of 1-25 mg PGF2alpha on Day 6 of dioestrus was as effective as 10 mg PGF2alpha in inducing luteolysis. Oestrus and ovulation appeared to be synchronized when a single injection of 1-25 mg PGF2alpha was given on Days 7, 10 or 13 after ovulation but not on Days 1 or 4 after ovulation or on Day 2 of oestrus. Intramuscular administration was as effective as subcutaneous administration and 1-25 mg PGF2alpha was the minimal effective systemic dose...
Recent observations concerning Klebsiella infections in stallions. A high incidence of Klebsiella contamination in German 'Warmblut' and Thoroughbred stallions is reported. The organism was recovered from the nostrils, prepuce, pre-ejacultory secretion and, in some cases, on the body surface, in the faeces and on the ground of the covering (mating) yard. Fertility was not affected. However, differences of virulence were observed and Type 5 proved to be the most pathogenic.
Oestrogen excretion in mares in relation to various reproductive states. The rate of urinary oestrogen excretion was studied in four ovariectomized mares. In two animals ovariectomized when urinary oestrogen concentration was high, levels fell to a minimun within 48 hr. Intramuscular injection of oestradiol-17beta produced maximum urinary oestrogen levels within 3 to 6 hr and a return to minimum detectable levels within 24 hr. The major urinary oestrogen in mares was oestrone. In nine maiden mares studied between September and June, the cycle, the durations of dioestrus and oestrus, and the time of ovulation were similar in autumn (September to December) and spring...
Androgens and oestrogens in normal and cryptorchid stallions. Total androgens, testosterone and total oestrogens were measured in twenty-one intact, nine unilaterally cryptorchid, three bilaterally cryptorchid stallions and four geldings. Total oestrogens were significantly higher (P less than 0-005) and total androgens significantly lower (P less than 0-05) in the bilateral cryptorchid compared to other groups. There was a significant (P less than 0-025) day and night variation in total androgen levels. Thyroidectomized and intact animals showed a marked decrease in total androgen as well as testosterone levels during the winter period thus showing an e...
