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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Effect of Treadmill Exercise and Hydrogen-rich Water Intake on Serum Oxidative and Anti-oxidative Metabolites in Serum of Thoroughbred Horses.
Journal of equine science    April 16, 2013   Volume 24, Issue 1 1-8 doi: 10.1294/jes.24.1
Tsubone H, Hanafusa M, Endo M, Manabe N, Hiraga A, Ohmura H, Aida H.The present study aimed to clarify changes of oxidative stress and antioxidative functions in treadmill-exercised Thoroughbred horses (n=5, 3 to 7 years old), using recently developed techniques for measurement of serum d-ROMs for oxidative stress, and BAP for antioxidative markers. Also, the effect of nasogastric administration of hydrogen-rich water (HW) or placebo water preceding the treadmill exercise on these parameters was examined. Each horse was subjected to a maximum level of treadmill exercise in which the horses were exhausted at an average speed of 13.2 ± 0.84 m/sec. Blood samples...
Development of a focus-reduction neutralizing test for detecting equine herpesvirus type-1-neutralizing antibodies.
The Journal of veterinary medical science    April 16, 2013   Volume 75, Issue 9 1209-1212 doi: 10.1292/jvms.13-0043
Bannai H, Nemoto M, Tsujimura K, Yamanaka T, Kondo T, Matsumura T.Virus-neutralizing (VN) testing is essential for evaluating virus-specific immunity in equine herpesvirus type-1 (EHV-1) infection. We developed a focus-reduction neutralization test (FRNT) for EHV-1 using 96-well plates for faster large-scale testing with sufficient sensitivity. We used an overlay medium containing Avicel (FMC Biopolymer), a microcrystalline cellulose with lower viscosity than the methylcellulose. The foci were visualized by immuno-staining with anti-EHV-1 gp14 monoclonal antibody. The FRNT successfully detected seroconversion in horses experimentally infected with EHV-1 (n =...
Comparison of cytological and histological examinations in different locations of the equine uterus-an in vitro study.
Theriogenology    April 16, 2013   Volume 79, Issue 9 1262-1268 doi: 10.1016/j.theriogenology.2013.02.007
Overbeck W, Jäger K, Schoon HA, Witte TS.Endometritis constitutes a major problem in managing broodmares. The histological occurrence of polymorphonuclear neutrophils (PMNs) in the stratum compactum of the endometrium is accepted as the reference standard to diagnose endometritis in mares. The objective of this study was to determine the distribution of PMNs within different sampling locations of the uterus by cytological examinations and to compare it with PMN numbers in endometrial biopsies of the corresponding location. Cytological and endometrial samples were obtained from 37 uteri within 2 ± 1 hours after slaughter through smal...
Equine grass sickness: what’s new?
The Veterinary record    April 16, 2013   Volume 172, Issue 15 393-394 doi: 10.1136/vr.f2191
Schwarz B.No abstract available
Endometrial inflammatory markers of the early immune response in mares susceptible or resistant to persistent breeding-induced endometritis.
Reproduction (Cambridge, England)    April 13, 2013   Volume 145, Issue 3 289-296 doi: 10.1530/rep-12-0452
Woodward EM, Christoffersen M, Campos J, Betancourt A, Horohov D, Scoggin KE, Squires EL, Troedsson MH.Transient endometritis after breeding is necessary for clearance of bacteria and spermatozoa; however, in a subpopulation of mares, the inflammation fails to resolve in a timely fashion. The objective of this study was to describe the uterine inflammatory response in mares susceptible or resistant to persistent breeding-induced endometritis (PBIE) during the first 24 h after induction of uterine inflammation.Twelve mares were classified as susceptible (nZ6) or resistant (nZ6) to PBIE. Mares were inseminated over five estrous cycles and endometrial biopsies were collected at one time point per ...
Influence of seroreactivity to leptospira and reproductive failures in recipient mares of equine embryo transfer programmes.
Reproduction in domestic animals = Zuchthygiene    April 13, 2013   Volume 48, Issue 4 e55-e57 doi: 10.1111/rda.12166
Pinna A, Martins G, Souza G, Lilenbaum W.The aim of this study was to demonstrate that seroreactivity against Leptospira is significantly associated to the reproductive efficiency of recipient mares of an embryo transfer (ET) programme. A serosurvey was conducted from August 2007 to March 2009 in five herds from Rio de Janeiro, Brazil, with high rates of reproductive failure, as early embryonic death (>12%), abortion (>12%) and perinatal death. Detailed information about the losses was obtained from practitioner. A total of 338 recipient mares were tested by microscopic agglutination test, and 226 (66.9%) were seroreactive, mainly ag...
Stem cells boom in vet clinics.
Nature    April 13, 2013   Volume 496, Issue 7444 148-149 doi: 10.1038/496148a
Cyranoski D.No abstract available
Strangles: taking steps towards eradication.
Veterinary microbiology    April 12, 2013   Volume 167, Issue 1-2 50-60 doi: 10.1016/j.vetmic.2013.03.033
Waller AS.Strangles, caused by the host adapted Lancefield group C bacterium Streptococcus equi sub-species equi (S. equi), is one of the oldest recognised infectious diseases of horses and continues to cause significant welfare and economic cost throughout the world. The ability of S. equi to establish sub-clinical persistent infections primarily in the guttural pouches of convalescent horses has been instrumental to its success. However, the implementation of simple control measures that permit the identification and treatment of persistently infected carriers can prevent further outbreaks of disease ...
The expression of mucin genes and the presence of mucin gene products in the equine endometrium.
Research in veterinary science    April 11, 2013   Volume 95, Issue 1 169-175 doi: 10.1016/j.rvsc.2013.03.012
Maischberger E, Cummins CA, Fitzpatrick E, Gallagher ME, Worrall S, Rousseau K, Thornton DJ, Meijer WG, Miranda-Casoluengo R, Duggan VE....In the equine reproductive tract, little is known about mucin gene expression and the role of mucins in barrier function and host-cell interaction. The aims of the study were to identify equine orthologs of mammalian mucin genes using available equine sequence data, to profile expression of equine orthologous mucin genes in the endometrium using reverse transcriptase polymerase chain reaction (RT-PCR), to determine spatial expression patterns of mucin genes using in situ hybridisation, and to confirm the presence of mucin gene products using Western blotting and equine-specific mucin antibodie...
Serum amyloid A and haptoglobin concentrations in serum and peritoneal fluid of healthy horses and horses with acute abdominal pain.
Veterinary clinical pathology    April 11, 2013   Volume 42, Issue 2 177-183 doi: 10.1111/vcp.12031
Pihl TH, Andersen PH, Kjelgaard-Hansen M, Mørck NB, Jacobsen S.Peritoneal fluid (PF) analysis is a valuable diagnostic tool in equine medicine. Markers such as serum amyloid A (SAA) and haptoglobin (Hp) could facilitate the diagnosis of inflammatory abdominal conditions. Objective: The objectives were to (1) establish reference intervals (RI) for SAA and Hp in serum and PF in healthy horses, (2) compare SAA and Hp concentrations between healthy horses and horses with colic, and (3) to assess the correlation between serum and PF concentrations. Methods: Serum amyloid A and Hp concentrations were determined by automated assays in prospectively enrolled heal...
Peeling back the evolutionary layers of molecular mechanisms responsive to exercise-stress in the skeletal muscle of the racing horse.
DNA research : an international journal for rapid publication of reports on genes and genomes    April 11, 2013   Volume 20, Issue 3 287-298 doi: 10.1093/dnares/dst010
Kim H, Lee T, Park W, Lee JW, Kim J, Lee BY, Ahn H, Moon S, Cho S, Do KT, Kim HS, Lee HK, Lee CK, Kong HS, Yang YM, Park J, Kim HM, Kim BC, Hwang S....The modern horse (Equus caballus) is the product of over 50 million yrs of evolution. The athletic abilities of the horse have been enhanced during the past 6000 yrs under domestication. Therefore, the horse serves as a valuable model to understand the physiology and molecular mechanisms of adaptive responses to exercise. The structure and function of skeletal muscle show remarkable plasticity to the physical and metabolic challenges following exercise. Here, we reveal an evolutionary layer of responsiveness to exercise-stress in the skeletal muscle of the racing horse. We analysed differentia...
Conceptualising the Impact of Arousal and Affective State on Training Outcomes of Operant Conditioning.
Animals : an open access journal from MDPI    April 11, 2013   Volume 3, Issue 2 300-317 doi: 10.3390/ani3020300
Starling MJ, Branson N, Cody D, McGreevy PD.Animal training relies heavily on an understanding of species-specific behaviour as it integrates with operant conditioning principles. Following on from recent studies showing that affective states and arousal levels may correlate with behavioural outcomes, we explore the contribution of both affective state and arousal in behavioural responses to operant conditioning. This paper provides a framework for assessing how affective state and arousal may influence the efficacy of operant training methods. It provides a series of three-dimensional conceptual graphs as exemplars to describing putati...
Reply to Andy Durham.
Equine veterinary journal    April 10, 2013   Volume 45, Issue 3 388-389 doi: 10.1111/evj.12073
Suthers J, Proudman C, Pinchbeck G, Archer D.No abstract available
Pharmacodynamics of multi-dose low molecular weight heparin in healthy horses.
Veterinary surgery : VS    April 10, 2013   Volume 42, Issue 4 448-454 doi: 10.1111/j.1532-950X.2013.12008.x
Whelchel DD, Tennent-Brown BS, Giguère S, Epstein KL.To compare the pharmacodynamics of once daily and twice daily administration of low molecular weight heparin (LMWH) administration in horses. Methods: Randomized cross over study. Methods: Adult mixed breed healthy mares (n = 6). Methods: LMWH (dalteparin) was administered (50 U/kg subcutaneously) either every 12 or 24 hours for 3 consecutive days. Anti-factor Xa activity was measured before and at select time points after LMWH administration. Packed cell volume (PCV), platelet count, partial thromboplastin time (PTT), and anti-thrombin (AT) activity were monitored throughout the study. Result...
Genetics of anti-EHV antibody responses in a horse population.
Research in veterinary science    April 10, 2013   Volume 95, Issue 1 137-142 doi: 10.1016/j.rvsc.2013.03.011
Rusek J, Klumplerova M, Molinkova D, Sedlinska M, Dusek L, Muzik J, Putnova L, Vrtkova I, Celer V, Horin P.Individual variation in immune responses to herpesviruses was observed in various species. Here, associations between polymorphic molecular markers and life-long anti-EHV-1/4 antibody immune responses were analyzed in a model EHV-infected population of the Old Kladruber horses. Two-dimensional analysis including overall mean titers and titer dynamics expressed by differences between spring and autumn titers allowed identification of low-responders. 50 randomly selected microsatellites and nine single nucleotide polymorphisms in nine immunity-related candidate genes were genotyped. Due to diffe...
Comment on Suthers and colleagues.
Equine veterinary journal    April 10, 2013   Volume 45, Issue 3 388 doi: 10.1111/evj.12072
Durham A.No abstract available
Replication and immunogenicity of swine, equine, and avian h3 subtype influenza viruses in mice and ferrets.
Journal of virology    April 10, 2013   Volume 87, Issue 12 6901-6910 doi: 10.1128/JVI.03520-12
Baz M, Paskel M, Matsuoka Y, Zengel J, Cheng X, Jin H, Subbarao K.Since it is difficult to predict which influenza virus subtype will cause an influenza pandemic, it is important to prepare influenza virus vaccines against different subtypes and evaluate the safety and immunogenicity of candidate vaccines in preclinical and clinical studies prior to a pandemic. In addition to infecting humans, H3 influenza viruses commonly infect pigs, horses, and avian species. We selected 11 swine, equine, and avian H3 influenza viruses and evaluated their kinetics of replication and ability to induce a broadly cross-reactive antibody response in mice and ferrets. The swin...
Seek and ye shall find: cardiac arrhythmias in the horse.
Equine veterinary journal    April 10, 2013   Volume 45, Issue 3 270-272 doi: 10.1111/evj.12054
Physick-Sheard PW.No abstract available
Surgical treatment of distal tarsal joint luxations in three horses.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    April 10, 2013   Volume 26, Issue 4 304-310 doi: 10.3415/VCOT-12-07-0094
Abuja GA, Bubeck KA, Quinteros DD, García-López JM.The clinical signs, radiographic findings, surgical treatment, and outcome of three horses with luxation of the distal tarsal joints are reported. Two patients showed luxations of the tarsometatarsal joint whereas luxation of the proximal intertarsal joint was found in one case. Open reduction, followed by internal fixation was performed in two horses and closed reduction with a transfixation pin cast was performed in the third. The treatment in all three cases resulted in a satisfactory clinical outcome.
Clostridium difficile infection in horses: a review.
Veterinary microbiology    April 10, 2013   Volume 167, Issue 1-2 42-49 doi: 10.1016/j.vetmic.2013.03.032
Diab SS, Songer G, Uzal FA.Clostridium difficile is considered one of the most important causes of diarrhea and enterocolitis in horses. Foals and adult horses are equally susceptible to the infection. The highly resistant spore of C. difficile is the infectious unit of transmission, which occurs primarily via the fecal-oral route, with sources of infection including equine feces, contaminated soil, animal hospitals, and feces of other animals. Two major risk factors for the development of C. difficile associated disease (CDAD) in adult horses are hospitalization and antimicrobial treatment, although sporadically, cases...
The demise of the UK’s National Equine Database.
Equine veterinary journal    April 10, 2013   Volume 45, Issue 3 269 doi: 10.1111/evj.12060
Owers R, Meldrum K.No abstract available
Getting a feel for equine colic.
The Veterinary record    April 9, 2013   Volume 172, Issue 14 354 doi: 10.1136/vr.f2119
No abstract available
Inactivated and adjuvanted vaccine for the control of the African horse sickness virus serotype 9 infection: evaluation of efficacy in horses and guinea-pig model.
Veterinaria italiana    April 9, 2013   Volume 49, Issue 1 89-98 
Lelli R, Molini U, Ronchi GF, Rossi E, Franchi P, Ulisse S, Armillotta G, Capista S, Khaiseb S, Di Ventura M, Pini A.African horse sickness (AHS) is a non-contagious viral disease of solipeds transmitted by Culicoides. The disease is endemic in most African countries. Past experience has shown that Italy is a country exposed to emerging infectious diseases endemic to Africa; an incursion of AHS virus together with the widespread presence of Culicoides vectors could be the cause of a serious epidemic emergency. A live attenuated vaccine containing seven of the nine viral serotypes, serotype 5 and 9 are excluded, is commercially available from Onderstepoort Biological Products. However, the use of live vaccine...
Descriptive epidemiology and risk factors for eliminations from Fédération Equestre Internationale endurance rides due to lameness and metabolic reasons (2008-2011).
Equine veterinary journal    April 9, 2013   Volume 46, Issue 1 38-44 doi: 10.1111/evj.12069
Nagy A, Murray JK, Dyson SJ.There is limited information on international endurance rides and on risk factors for eliminations. Objective: To describe and compare the frequency of occurrence of elimination due to lameness and metabolic reasons from Fédération Equestre Internationale (FEI) endurance rides (≥100 km) during 2008-2011 in all countries and to assess risk factors for elimination due to lameness and metabolic reasons. Methods: Retrospective unmatched case-control study. Methods: Data collected from the FEI website included the following: the country where the ride was held; the year; the result for each hor...
Distribution and persistence of technetium-99 hexamethyl propylene amine oxime-labelled bone marrow-derived mesenchymal stem cells in experimentally induced tendon lesions after intratendinous injection and regional perfusion of the equine distal limb.
Equine veterinary journal    April 9, 2013   Volume 45, Issue 6 726-731 doi: 10.1111/evj.12063
Sole A, Spriet M, Padgett KA, Vaughan B, Galuppo LD, Borjesson DL, Wisner ER, Vidal MA.Intralesional (i.l.) injection is currently the most commonly used technique for stem cell therapy in equine tendon injury. A comparison of different techniques of injection of mesenchymal stem cells for the treatment of tendon lesions is required. Objective: We hypothesised that vascular perfusion of the equine distal limb with mesenchymal stem cells (MSCs) would result in preferential distribution of MSCs to acute tendon injuries. Methods: In vivo experimental study. Methods: Lesions were surgically induced in forelimb superficial digital flexor tendons of 8 horses. Three or 10 days after le...
Equine influenza–a global perspective.
Veterinary microbiology    April 9, 2013   Volume 167, Issue 1-2 205-214 doi: 10.1016/j.vetmic.2013.03.029
Cullinane A, Newton JR.To date, equine influenza outbreaks have been reported all over the world with the exception of a small number of island nations including New Zealand and Iceland. Influenza is endemic in Europe and North America and is considered to be of potentially major economic significance to the equine industry worldwide. The importation of subclinically infected vaccinated horses, and inadequate quarantine procedures have resulted in several major outbreaks in susceptible populations for example, in Australia (2007) when more than 76,000 horses on over 10,000 properties were reported as infected. This ...
Horse passport survey.
The Veterinary record    April 9, 2013   Volume 172, Issue 14 370 doi: 10.1136/vr.f2087
Jones P, Chandler K.No abstract available
Henipavirus infections: lessons from animal models.
Pathogens (Basel, Switzerland)    April 9, 2013   Volume 2, Issue 2 264-287 doi: 10.3390/pathogens2020264
Dhondt KP, Horvat B.The Henipavirus genus contains two highly lethal viruses, the Hendra and Nipah viruses and one, recently discovered, apparently nonpathogenic member; Cedar virus. These three, negative-sense single-stranded RNA viruses, are hosted by fruit bats and use EphrinB2 receptors for entry into cells. The Hendra and Nipah viruses are zoonotic pathogens that emerged in the middle of 90s and have caused severe, and often fatal, neurologic and/or respiratory diseases in both humans and different animals; including spillover into equine and porcine species. Development of relevant models is critical for a ...
Melanoma: More horses..
Nature reviews. Cancer    April 8, 2013   Volume 13, Issue 5 296-297 doi: 10.1038/nrc3512
McCarthy N.No abstract available
Epidemiology of intoxication of domestic animals by plants in Europe.
Veterinary journal (London, England : 1997)    April 6, 2013   Volume 197, Issue 2 163-168 doi: 10.1016/j.tvjl.2013.03.007
Cortinovis C, Caloni F.This review focuses on some of the most important poisonous plants in Europe and provides an overview of the poisoning episodes that have occurred in European countries. Poisoning of livestock and companion animals by plants is a relatively common occurrence. In Europe livestock and horses are commonly poisoned by Datura stramonium (Jimson weed), Senecio spp. (ragworts and groundsels), Quercus spp. (oak), Taxus baccata (European yew), Nerium oleander (oleander), Pteridium aquilinum (bracken fern), Robinia pseudoacacia (black locust) and Rhododendron spp. (rhododendrons and azaleas). Poisoning ...