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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Contemporary use of acepromazine in the anaesthetic management of male horses and ponies: a retrospective study and opinion poll.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 88-98 doi: 10.1111/j.2042-3306.2010.00107.x
Driessen B, Zarucco L, Kalir B, Bertolotti L.Current use of acepromazine in the anaesthetic management of male horses and ponies and associated risks are largely unknown. Objective: To explore anaesthetic acepromazine use and related adverse effects in the male horse. Methods: Of 8533 anaesthetised horses and ponies medical records of male animals treated perianaesthetically with acepromazine were reviewed. Demographic data, time and dose of acepromazine administration, co-administered drugs, quality of induction and recovery from anaesthesia, arterial blood pressures, and occurrence of penile dysfunction were recorded. Practising ACVA a...
The hidden menace of non-equine horses.
The Medical journal of Australia    December 15, 2010   Volume 193, Issue 11-12 724-725 doi: 10.5694/j.1326-5377.2010.tb04122.x
Craven JA, Schutz JK.An emergency department audit of horse-related injury presentations alerted researchers to a hitherto uninvestigated source of childhood harm: non-equine horses. A search for the term "horse" in the database of the South Australian Injury Surveillance and Control Unit was performed for presentations of horse-related injuries to a paediatric emergency department of an Australian tertiary teaching hospital over a 5-year period. After all equine-related episodes were extracted, the remaining presentations were herded together and conclusions were jumped to. When legitimate science and research te...
Presence of mononuclear cells in normal and affected laminae from the black walnut extract model of laminitis.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 45-53 doi: 10.1111/j.2042-3306.2010.00121.x
Faleiros RR, Nuovo GJ, Flechtner AD, Belknap JK.There is increasing evidence of involvement of inflammatory cells in acute laminitis. Objective: To immunolocalise monocytes/macrophages and B and T lymphocytes in the laminar tissue of normal horses and those with black walnut extract (BWE)-induced laminitis. Methods: Immunohistochemistry was used in archived laminar tissue samples from 20 horses divided equally into 4 groups: control animals (CON), and those administered BWE at 1.5 h (1.5H DTP group), at the onset of leucopenia (3H DTP group) and at the onset of lameness (LAM group). Antibodies against CD3, CD20 and CD163 were used to recogn...
Intrauterine administration of plant oils inhibits luteolysis in the mare.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 99-105 doi: 10.1111/j.2042-3306.2010.00131.x
Wilsher S, Allen WR.The maternal recognition of pregnancy (MRP) signal in the mare has not been determined, although oestrogens have been proposed as a potential candidate. Objective: To determine effects of intrauterine administration of oestrogen and various oils on cyclic luteolysis in the mare. Objective: Intrauterine oestradiol or fatty acids may suppress luteolysis in the cycling mare when administered during late dioestrus. Methods: A single 1 ml dose of slow-release oestradiol (10 mg/ml) in fractionated coconut oil was infused into the uterine lumen of cycling mares on Days 6, 8, 10, 12 or 14 post ovulati...
Cutaneous fungal granulomas due to Alternaria spp. infection in a horse in New Zealand.
New Zealand veterinary journal    December 15, 2010   Volume 58, Issue 6 319-320 doi: 10.1080/00480169.2010.69765
Dicken M, Munday JS, Archer RM, Mayhew IG, Pandey SK.Equine cutaneous fungal granulomas have been previously referred to in New Zealand (Fairley 1998), and are described in the veterinary literature from around the world, including North America and Australia (Pascoe and Summers 1981; Genovese et al. 2001; Valentine et al. 2006), but no peer-reviewed reports appear published in the literature in New Zealand. Described here is a case of multiple cutaneous fungal granulomas caused by Alternaria spp. in a horse in New Zealand.
Double-blind placebo-controlled study with interleukin-18 and interleukin-12-encoding plasmid DNA shows antitumor effect in metastatic melanoma in gray horses.
Journal of immunotherapy (Hagerstown, Md. : 1997)    December 15, 2010   Volume 34, Issue 1 58-64 doi: 10.1097/CJI.0b013e3181fe1997
Müller J, Feige K, Wunderlin P, Hödl A, Meli ML, Seltenhammer M, Grest P, Nicolson L, Schelling C, Heinzerling LM.Melanoma is a disease with high incidence in gray horses and has limited therapeutic options in metastatic disease. Gene therapy has shown some success in animal models and human patients. A randomized double-blind, placebo-controlled study was conducted to investigate 2 treatment options using cytokine-encoding plasmid DNA in horses with metastatic melanoma to induce immunologic antitumor effects. Adult gray horses with spontaneously occurring metastatic melanoma (n=26) were included in the study. Treatment of 26 gray horses with metastatic melanoma consisted of interleukin-18-encoding plasmi...
Association of owner-reported noise with findings during dynamic respiratory endoscopy in Thoroughbred racehorses.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 9-17 doi: 10.1111/j.2042-3306.2010.00152.x
Witte SH, Witte TH, Harriss F, Kelly G, Pollock P.To determine the association between owner-reported noise and findings during dynamic respiratory endoscopy (DRE) in a large case series. Objective: The sensitivity of owner-reported noise for dynamic upper respiratory tract obstructions in horses is low, and the specificity is high. Methods: One hundred horses underwent DRE for the investigation of abnormal respiratory noise and/or poor performance. The association of abnormal noise with findings during DRE was evaluated. Results: Eighty-five horses underwent DRE for the investigation of abnormal respiratory noise. Of these, 82% were found to...
Exercising upper respiratory videoendoscopic evaluation of 100 nonracing performance horses with abnormal respiratory noise and/or poor performance.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 3-8 doi: 10.1111/j.2042-3306.2010.00132.x
Davidson EJ, Martin BB, Boston RC, Parente EJ.Although well documented in racehorses, there is paucity in the literature regarding the prevalence of dynamic upper airway abnormalities in nonracing performance horses. Objective: To describe upper airway function of nonracing performance horses with abnormal respiratory noise and/or poor performance via exercising upper airway videoendoscopy. Methods: Medical records of nonracing performance horses admitted for exercising evaluation with a chief complaint of abnormal respiratory noise and/or poor performance were reviewed. All horses had video recordings of resting and exercising upper airw...
Welfare and health of horses transported for slaughter within the European Union Part 1: Methodology and descriptive data.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 78-87 doi: 10.1111/j.2042-3306.2010.00124.x
Marlin D, Kettlewell P, Parkin T, Kennedy M, Broom D, Wood J.Anecdotal evidence collected by a variety of organisations has highlighted poor welfare in horses transported long distances to slaughter within the European Union. Objective: To investigate welfare of horses being transported long distances within the EU to slaughter. Methods: Data on transported horses were recorded at 2 assembly centres in Romania and at 4 abattoirs in Italy over an 8 month period in 2008. Results: A total of 1519 horses in 64 separate shipments were observed in Romania prior to transport of which 212 horses were deemed unfit for transport and only 3 shipments (5%) complied...
PRINS detection of 18S rDNA in pig, red fox and Chinese raccoon dog, and centromere DNA in horse.
Hereditas    December 15, 2010   Volume 147, Issue 6 320-324 doi: 10.1111/j.1601-5223.2010.02201.x
Wnuk M, Oklejewicz B, Lewinska A, Zabek T, Bartosz G, Slota E, Bugno-Poniewierska M.The fluorescence in situ hybridization (FISH) technique is widely used in animal cytogenetics. Contrary to FISH procedure, primed in situ DNA synthesis (PRINS) does not require the DNA probe preparation (design, synthesis, gel purification of PCR products and labeling). The PRINS method with primers used as 'DNA probes' is both PCR-sensitive and allows for chromosomal localization of DNA sequences. Here, we show the application of PRINS reaction with one unlabeled oligonucleotide pair to identify 18S rDNA loci in three different animal species: domestic pig (Sus scrofa), red fox (Vulpes vulpes...
Intraspecific scaling of chewing cycle duration in three species of domestic ungulates.
The Journal of experimental biology    December 15, 2010   Volume 214, Issue Pt 1 104-112 doi: 10.1242/jeb.043646
Stover KK, Williams SH.In mammals, chewing cycle duration (CCD) increases with various measures of size, scaling with body mass(0.13-0.28) and jaw length(0.55). Proposed explanations for these scaling relationships include the allometry of body size, basal metabolic rate and tooth size, on the one hand, and pendular mechanics treating the jaw as a gravity-driven pendulum, on the other. Little is known, however, about the relationship between CCD and size within species. Recent research in dogs demonstrates altogether different scaling exponents and weaker correlations. This research suggests that breed-specific grow...
Recognition of pain and use of analgesia in horses by veterinarians in New Zealand.
New Zealand veterinary journal    December 15, 2010   Volume 58, Issue 6 274-280 doi: 10.1080/00480169.2010.69402
Waran N, Williams VM, Clarke N, Bridge IS.To explore attitudes towards and use of analgesia in horses by veterinarians in New Zealand. Methods: A postal questionnaire was sent out to 457 veterinarians identified as working with horses in New Zealand. Questions covered demographics and practice data; analgesic drugs available for use and used in practice; analgesic management of specific conditions including assessment of pain, drugs used, and frequency of cases; factors influencing the choice and use of analgesic agents; and attitudes and personal experience. Results: Ninety-seven questionnaires containing useable data were received, ...
Suspect novel adverse drug reactions to trimethoprim-sulphonamide combinations in horses: a case series.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 117-120 doi: 10.1111/j.2042-3306.2010.00158.x
Stack A, Schott HC.Adverse drug reactions to trimethoprim-sulphonamide combinations are common in many species, manifesting as gastrointestinal tract disorders, dermatopathies and blood dyscrasias. In this case series, neurological abnormalities in 4 horses being treated with trimethoprim-sulphonamide combinations at normal dosages and in one foal that received an overdose are described. The horses developed hypermetric gait, agitation and erratic behaviour. All signs resolved once medication was withdrawn, and no horse had residual deficits. No other cause for observed neurological deficits could be determined....
[Accuracy with the URA].
Tijdschrift voor diergeneeskunde    December 15, 2010   Volume 135, Issue 22 857-858 
Boissevain I.No abstract available
Laminar inflammatory gene expression in the carbohydrate overload model of equine laminitis.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 54-61 doi: 10.1111/j.2042-3306.2010.00122.x
Leise BS, Faleiros RR, Watts M, Johnson PJ, Black SJ, Belknap JK.There is a need to assess the laminar inflammatory response in a laminitis model that more closely resembles clinical cases of sepsis-related laminitis than the black walnut extract (BWE) model. Objective: To determine if a similar pattern of laminar inflammation, characterised by proinflammatory cytokine expression, occurs in the CHO model of laminitis as has been previously reported for the BWE model. Methods: Sixteen horses administered 17.6 g of starch (85% corn starch/15% wood flour)/kg bwt via nasogastric (NG) tube were anaesthetised either after developing a temperature>38.9°C (DEV ...
Equine odontoclastic tooth resorption and hypercementosis.
Australian veterinary journal    December 15, 2010   Volume 88, Issue 12 N23-N24 
Lee S.No abstract available
Correlation of resting and exercising endoscopic findings for horses with dynamic laryngeal collapse and palatal dysfunction.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 18-23 doi: 10.1111/j.2042-3306.2010.00108.x
Barakzai SZ, Dixon PM.To correlate resting and exercising endoscopic grades of laryngeal function in horses undergoing high-speed treadmill endoscopy (HSTE) using the Havemeyer grading system. To correlate dorsal displacement of the soft palate (DDSP) seen at rest with palatal function during exercise. Methods: Records of horses that underwent HSTE examination (1999-2009) were reviewed. Resting laryngeal function score and other abnormalities noted on resting endoscopy were recorded as were results of HSTE. Results of resting and exercising endoscopic findings were correlated. Results: 281 horses underwent HSTE. Th...
Evaluation of a novel post operative treatment for sinonasal disease in the horse (1996-2007).
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 24-29 doi: 10.1111/j.2042-3306.2010.00133.x
Hart SK, Sullins KE.Results of surgical treatment of sinonasal disease in horses have been reported previously; however, this paper describes the outcome of horses in which a specific post operative treatment protocol was used. Objective: The objectives of the study were to determine: 1) short- and long-term outcome; 2) complications; and 3) recurrence rates of different disease processes, when horses were treated with a specific treatment protocol. Methods: Medical records of horses presented for surgical treatment of sinonasal disease from 1996-2007 were reviewed. Results and duration of surgical exploration we...
The future of Equine Veterinary Journal.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 1 doi: 10.1111/j.2042-3306.2010.00342.x
Marr CM.No abstract available
Determination of tear break-up time reference values and ocular tolerance of tetracaine hydrochloride eyedops in healthy horses.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 74-77 doi: 10.1111/j.2042-3306.2010.00119.x
Monclin SJ, Farnir F, Grauwels M.Tetracaine hydrochloride (THCl) has been reported to cause irritation in dogs. In man, some topical anaesthetics have been shown to disrupt the tear film. Tear break-up time (TBUT) is a useful test allowing an assessment of the quality of the precorneal tear film. Only one TBUT value has been reported in horses with no information on the technique used. Objective: To provide a method for performing the TBUT in horses and to report any side effects of a single application of THCl in clinically normal horses, particularly on the stability of the tear film. Methods: In Study 1, one drop of 0.5 or...
Antibody coefficients for the diagnosis of equine protozoal myeloencephalitis.
Journal of veterinary internal medicine    December 14, 2010   Volume 25, Issue 1 138-142 doi: 10.1111/j.1939-1676.2010.0658.x
Furr M, Howe D, Reed S, Yeargan M.Diagnosis of equine protozoal myeloencephalitis (EPM) remains a challenge for equine practitioners. Current utilized methods have inadequate sensitivity and specificity, because of a high number of false positive results. Objective: Evaluation of antibody indices to Sarcocystis neurona should provide high sensitivity and specificity for diagnosis of EPM. Methods: Archived samples from 29 clinical patients. Methods: Archived serum and cerebrospinal fluid (CSF) samples from clinical patients with either EPM (14) or cervical vertebral compressive myelopathy (CVM) (15) were examined and tested for...
Amnion nodosum in a Belgian draught horse.
The Veterinary record    December 14, 2010   Volume 168, Issue 1 22 doi: 10.1136/vr.c5058
Govaere J, Vercauteren G, Coopmans C, Hoogewijs M, De Schauwer C, Smits K, de Kruif A.No abstract available
Axial sesamoid fracture causing deep digital flexor tendon damage in a horse.
The Veterinary record    December 14, 2010   Volume 168, Issue 2 50 doi: 10.1136/vr.c5262
Russell T, Hall M.No abstract available
Leptospira interrogans associated with hydrallantois in 2 pluriparous Thoroughbred mares.
Journal of veterinary internal medicine    December 13, 2010   Volume 25, Issue 1 158-161 doi: 10.1111/j.1939-1676.2010.0653.x
Shanahan LM, Slovis NM.No abstract available
Hypertrophic osteopathy secondary to nodular pulmonary fibrosis in a horse.
Journal of veterinary internal medicine    December 13, 2010   Volume 25, Issue 1 153-157 doi: 10.1111/j.1939-1676.2010.0652.x
Tomlinson JE, Divers TJ, McDonough SP, Thompson MS.No abstract available
Receptor-mediated enhancement of beta adrenergic drug activity by ascorbate in vitro and in vivo.
PloS one    December 13, 2010   Volume 5, Issue 12 e15130 doi: 10.1371/journal.pone.0015130
Dillon PF, Root-Bernstein R, Robinson NE, Abraham WM, Berney C.Previous in vitro research demonstrated that ascorbate enhances potency and duration of activity of agonists binding to alpha 1 adrenergic and histamine receptors. Objective: Extending this work to beta 2 adrenergic systems in vitro and in vivo. Methods: Ultraviolet spectroscopy was used to study ascorbate binding to adrenergic receptor preparations and peptides. Force transduction studies on acetylcholine-contracted trachealis preparations from pigs and guinea pigs measured the effect of ascorbate on relaxation due to submaximal doses of beta adrenergic agonists. The effect of inhaled albuter...
Perosomus elumbis, cerebral aplasia, and spina bifida in an aborted thoroughbred foal.
Research in veterinary science    December 13, 2010   Volume 92, Issue 2 266-268 doi: 10.1016/j.rvsc.2010.11.009
Gerhauser I, Geburek F, Wohlsein P.Perosomus elumbis represents a rare congenital anomaly characterized by aplasia of the lumbosacral spinal cord and vertebrae. This anomaly is often associated with arthrogryposis and malformations of the urogenital and intestinal tract. This report describes the first case of perosomus elumbis in an aborted Thoroughbred foal associated with cerebral aplasia with meningocele, cranioschisis, spina bifida, a fused urogenital and intestinal tracts lined by a cutaneous mucosa without uterine glands, atresia ani, and arthrogryposis of the hind legs. Immunohistochemistry detected no abnormalities in ...
Effect of training and detraining on monocarboxylate transporter (MCT) 1 and MCT4 in Thoroughbred horses.
Experimental physiology    December 10, 2010   Volume 96, Issue 3 348-355 doi: 10.1113/expphysiol.2010.055483
Kitaoka Y, Masuda H, Mukai K, Hiraga A, Takemasa T, Hatta H.The aim of this study was to investigate the effects of training and detraining on the monocarboxylate transporter (MCT) 1 and MCT4 levels in the gluteus medius muscle of Thoroughbred horses. Twelve Thoroughbred horses were used for the analysis. For 18 weeks, all the horses underwent high-intensity training (HIT), with running at 90-110% maximal oxygen consumption (VO2 max ) for 3 min, 5 days week(-1). Thereafter, the horses either underwent detraining for 6 weeks by either 3 min of moderate-intensity training (MIT) at 70% VO2 max, 5 days week(-1) (HIT-MIT group) or stall rest (HIT-SR group)....
Predictors of race-day jockey falls in jumps racing in Australia.
Accident; analysis and prevention    December 9, 2010   Volume 43, Issue 3 840-847 doi: 10.1016/j.aap.2010.11.003
Hitchens P, Blizzard L, Jones G, Day L, Fell J.Thoroughbred jumps racing jockeys have a fall rate greater than their flat racing counterparts. Previous studies have focused on factors that contribute to falls by horses but, to date, there has not been a study of risk factors for falls to jockeys in jumps races. Data on race-day falls were extracted from stipendiary stewards reports lodged with Principal Racing Authorities following each race meeting. Denominator data were provided by Racing Information Services Australia on races conducted from August 2002 until July 2009. Univariable and multivariable analyses, estimating incidence rate r...
Biomarkers of brain injury in foals with hypoxic-ischemic encephalopathy.
Journal of veterinary internal medicine    December 8, 2010   Volume 25, Issue 1 132-137 doi: 10.1111/j.1939-1676.2010.0645.x
Ringger NC, Giguère S, Morresey PR, Yang C, Shaw G.Neonatal hypoxic-ischemic encephalopathy (NHIE) is a disease affecting newborn foals for which there is no antemortem diagnostic test. Objective: Ubiquitin C-terminal hydrolase 1 (UCHL1) and the phosphorylated axonal forms of neurofilament H (pNF-H) are markers of brain injury in foals with NHIE. Methods: Thirty-three foals with a clinical diagnosis consistent with NHIE and 17 healthy foals. Methods: Retrospective study. Concentrations of UCHL1 and pNF-H in plasma were measured by ELISA. The performance of the assays for the diagnosis of NHIE was assessed by receiver operating characteristic c...