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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Field fertility of sex-sorted and non-sorted frozen-thawed stallion spermatozoa.
Animal reproduction science    September 16, 2007   Volume 108, Issue 3-4 287-297 doi: 10.1016/j.anireprosci.2007.08.015
Clulow JR, Buss H, Sieme H, Rodger JA, Cawdell-Smith AJ, Evans G, Rath D, Morris LH, Maxwell WM.In the 2004/2005 breeding season, the fertility of sex-sorted (SS) and non-sorted (NS) frozen stallion spermatozoa from two Hannovarian stallions was compared. A hysteroscopic insemination technique [Morris, L.H., Tiplady, C., Allen, W.R., 2003a. Pregnancy rates in mares after a single fixed time hysteroscopic insemination of low numbers of frozen-thawed spermatozoa onto the uterotubal junction. Equine Vet. J. 35, 197-201] was used to deposit low doses (6, 13 or 25 x 10(6) frozen-thawed SS or NS spermatozoa) onto the utero-tubal junction at 32 or 38 h after the administration of Chorulon (2500...
Cytokine expression by peripheral blood neutrophils from heaves-affected horses before and after allergen challenge.
Veterinary journal (London, England : 1997)    September 14, 2007   Volume 178, Issue 2 227-232 doi: 10.1016/j.tvjl.2007.07.027
Joubert P, Cordeau ME, Boyer A, Silversides DW, Lavoie JP.Heaves, also known as recurrent airway obstruction, is a common condition of horses characterised by pulmonary neutrophilia and reversible airway obstruction. This study evaluated the role of neutrophils in producing cytokines and chemokines that might be involved in the recruitment and activation of inflammatory cells in horses with heaves. Peripheral neutrophils were isolated from heaves-affected (n = 9) and control (n = 4) horses before and after 5 h of natural inhalation challenge. Expression of mRNA of two pro-inflammatory cytokines, tumour necrosis factor (TNF)-alpha and interleukin (IL)...
Determination of glucosamine in horse plasma by liquid chromatography tandem mass spectrometry.
Biomedical chromatography : BMC    September 13, 2007   Volume 22, Issue 1 1-4 doi: 10.1002/bmc.906
Beaudry F, Vachon P.Glucosamine is an amino sugar involved in the biosynthesis of glycosylated proteins and lipids. Recently, with increased public interest in natural products medicine, glucosamine has been widely used to treat osteoarthritis, even though demonstrations of its actual efficacy remain relatively unknown. Information related to the pharmcokinetics of glucosamine is sparse. A recent analytical method published used 13C-glucosamine as an internal standard to analyse study samples. The method lacked accuracy owing to an important natural isotopic contribution of glucosamine to 13C-glucosamine ion abun...
Serum concentration of copper, zinc, iron, and cobalt and the copper/zinc ratio in horses with equine herpesvirus-1.
Biological trace element research    September 13, 2007   Volume 118, Issue 1 38-42 doi: 10.1007/s12011-007-0023-y
Yörük I, Deger Y, Mert H, Mert N.The serum concentrations of copper, zinc, iron, and cobalt and copper/zinc ratio were investigated in horses infected with equine herpesvirus-1 (EHV-1). Nine horses were naturally infected with the virus and nine healthy horses served as controls. The concentrations of copper, zinc, iron, and cobalt were determined spectrophotometrically in the blood serum of all horses. The results were (expressed in micrograms per deciliters) copper 2.80 +/- 0.34 vs 1.12 +/- 0.44, zinc 3.05 +/- 0.18 vs 0.83 +/- 0.06, iron 2.76 +/- 0.17 vs 3.71 +/- 0.69, cobalt 0.19 +/- 0.37 vs 0.22 +/- 0.45, and copper/zinc ...
Immunohistochemical localization of vascular endothelial growth factor (VEGF) and its two receptors (Flt-I and KDR) in the endometrium and placenta of the mare during the oestrous cycle and pregnancy.
Reproduction in domestic animals = Zuchthygiene    September 12, 2007   Volume 42, Issue 5 516-526 doi: 10.1111/j.1439-0531.2006.00815.x
Allen WR, Gower S, Wilsher S.Polyclonal antisera for vascular endothelial growth factor (VEGF) and its two main receptor molecules, VEGF-I (Flt) and VEGF-II (KDR), were used in a conventional immunocytochemical staining method to localize these angiogenic ligand molecules in the endometrium and placenta of the mare during the oestrous cycle and pregnancy. The anti-VEGF and anti-Flt sera both labelled the lumenal and glandular epithelia of the endometrium throughout the oestrous cycle and both the invasive trophoblast cells of the endometrial cups and the non-invasive trophoblast of the allantochorion in pregnancy. The ant...
Comparison of different molecular methods for assessment of equine arteritis virus (EAV) infection: a novel one-step MGB real-time RT-PCR assay, PCR-ELISA and classical RT-PCR for detection of highly diverse sequences of Slovenian EAV variants.
Journal of virological methods    September 12, 2007   Volume 146, Issue 1-2 341-354 doi: 10.1016/j.jviromet.2007.07.019
Mankoc S, Hostnik P, Grom J, Toplak I, Klobucar I, Kosec M, Barlic-Maganja D.In the present study, a new one-step real-time reverse transcription-polymerase chain reaction (RT-PCR) strategy with minor-groove-binder (MGB) technology for the detection of EAV from 40 semen samples of Slovenian carrier stallions was tested. A novel MGB probe (EAVMGBpr) and a reverse primer (EAV-R) based on the multiple sequence alignment of 49 different EAV strain sequences of the highly conserved ORF7 (nucleocapsid gene) were designed. The performance of the assay was compared with different molecular detection methods. Three different primer pairs targeting the ORF1b and ORF7 were used, ...
A single subcutaneous administration of buserelin induces ovulation in the mare: field data.
Reproduction in domestic animals = Zuchthygiene    September 12, 2007   Volume 42, Issue 5 550-554 doi: 10.1111/j.1439-0531.2006.00822.x
Levy I, Duchamp G.The aim of the present study, was to evaluate whether a single subcutaneous administration of the GnRH analogue buserelin could induce ovulation in the mare during the breeding season. Two studies were carried out under field conditions. In Experiment 1, 90 cycles of trotter mares aged 2-7 years, were assigned to a buserelin group (Bus1) or to a control group (Control), in the presence of a >/=35 mm pre-ovulatory follicle, with uterine oedema and a relaxed cervix. Ten mares were assigned to the two groups for 32 cycles in Bus1 and 52 cycles in Control, two mares received only Bus1 for three...
Accuracy of a rapid enzyme-linked immunosorbent assay to measure progesterone in mares.
The Canadian veterinary journal = La revue veterinaire canadienne    September 11, 2007   Volume 48, Issue 8 823-826 
Relave F, Lefebvre RC, Beaudoin S, Price C.The aim of this study was to validate an enzyme-linked immunosorbent assay (ELISA) for the measurement of progesterone (P4) in mares. Specifically, the objectives were as follows: (1) to determine the specificity and sensitivity of the ELISA test for determination of P4, (2) to measure the potential agreement between the 2 people performing the test, and 3) to evaluate the effect of time on the outcome. Ten mares were sampled on the day before ovulation (D-1), and on days 1 (D1), 3 (D3), and 5 (D5) following ovulation, during the reproductive season. While mares were cycling regularly, estrus ...
Comparative study of doramectin and fipronil in the treatment of equine chorioptic mange.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 335-338 doi: 10.1136/vr.161.10.335
Rendle DI, Cottle HJ, Love S, Hughes KJ.In equids, chorioptic mange is a common dermatitis for which there are no licensed medications in the uk. Doramectin and fipronil are licensed for the control of ectoparasites in other species and were evaluated for the treatment of 17 cases of chorioptic mange in 13 equids. Equids were included if clinical findings were indicative of chorioptic mange, chorioptes mites were positively identified and concurrent disease that could affect response to disease was not evident. A random number table was used to allocate subjects to receive doramectin (group D, eight animals) or fipronil (group F, ni...
Pulmonary function and antimicrobial concentration after marbofloxacin inhalation in horses.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 348-350 doi: 10.1136/vr.161.10.348
Art T, de Moffarts B, Bedoret D, van Erck E, Lekeux P.No abstract available
Evaluation of serum amyloid A and surfactant protein D in sera for identification of the clinical condition of horses with bacterial pneumonia.
The Journal of veterinary medical science    September 11, 2007   Volume 69, Issue 8 827-830 doi: 10.1292/jvms.69.827
Hobo S, Niwa H, Anzai T.In the present study, the concentrations of serum amyloid A and surfactant protein D in sera were measured to evaluate them for identification of the clinical condition of horses with bacterial pneumonia. The study utilized 185 clinically healthy control thoroughbreds and 9 thoroughbreds for experimental infectious study with S. zooepidemicus. Blood samples were collected from the 185 healthy control thoroughbreds. The 9 thoroughbreds were experimentally infected S. zooepidemicus using an endoscopic injection to a lung lobe and were then observed of clinical conditions. Blood samples were coll...
Use of matrix metalloproteinases 2 and 9 and white blood cell counts in monitoring the treatment and predicting the survival of horses with septic arthritis.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 329-334 doi: 10.1136/vr.161.10.329
Kidd JA, Barr AR, Tarlton JF.Thirty-nine samples of synovial fluid were collected from the joints of 32 horses with suspected septic arthritis and 39 samples were collected from horses euthanased for non-orthopaedic conditions. The white blood cell counts (WBCC) were determined and the pro and active forms of matrix metalloproteinases (MMPs) 2 and 9 were measured by gelatin zymography and image analysis in each sample. The initial measurements of the ratio of proMMP9:proMMp2 and WBCC were good prognostic indicators of the survival of the horses. There was no significant relationship between the interval between the injury...
MRSA infection in horses.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 359-360 doi: 10.1136/vr.161.10.359-a
Weese JS.No abstract available
Detection of antibodies to equine arteritis virus in horse sera using recombinant chimaeric N/G(L) protein.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 352-354 doi: 10.1136/vr.161.10.352
Turan N, Ekici H, Yilmaz H, Kondo T, Hasoksuz M, Sato I, Tuchiya K, Fukunaga Y.No abstract available
Short-term effects of energy changes on plasma leptin concentrations and glucose tolerance in healthy ponies.
Veterinary journal (London, England : 1997)    September 11, 2007   Volume 178, Issue 2 233-237 doi: 10.1016/j.tvjl.2007.07.018
Weyenberg SV, Hesta M, Buyse J, Papadopoulos GA, Janssens GP.To determine whether plasma leptin concentrations and glucose tolerance are affected by changes in energy balance, nine healthy Shetland ponies were fed at 140% followed by 75% of their maintenance requirements for 13 days in each of the two periods. Bodyweight was recorded every three days. Blood samples were taken every two days and analysed for leptin and cortisol. An oral glucose tolerance test was performed on day 7 of each period. Serial blood samples were analysed for glucose and insulin. Although bodyweight was not affected, plasma leptin concentrations increased (P<0.001) initially...
Removal of a sialolith by an intraoral surgical approach in a warmblood gelding.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 354-356 doi: 10.1136/vr.161.10.354
Haralambus RM, Simhofer H, Zappe H.No abstract available
Morphologic changes associated with functional adaptation of the navicular bone of horses.
Journal of anatomy    September 11, 2007   Volume 211, Issue 5 662-672 doi: 10.1111/j.1469-7580.2007.00800.x
Bentley VA, Sample SJ, Livesey MA, Scollay MC, Radtke CL, Frank JD, Kalscheur VL, Muir P.Failure of functional adaptation to protect the skeleton from damage is common and is often associated with targeted remodeling of bone microdamage. Horses provide a suitable model for studying loading-related skeletal disease because horses are physically active, their exercise is usually regulated, and adaptive failure of various skeletal sites is common. We performed a histologic study of the navicular bone of three groups of horses: (1) young racing Thoroughbreds (n = 10); (2) young unshod ponies (n = 10); and (3) older horses with navicular syndrome (n = 6). Navicular syndrome is a painfu...
Detection of an isoform of alpha(1)-antitrypsin in serum samples from foals with gastric ulcers.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 338-342 doi: 10.1136/vr.161.10.338
Taharaguchi S, Nagano A, Okai K, Miyasho T, Kuwano M, Taniyama H, Yokota H.The objective of this study was to find serum indicators of gastric ulcers in foals. By using two-dimensional electrophoresis of serum proteins, three distinct spots were detected in samples from foals with gastric ulcers detected endoscopically. One of them appeared with high frequency and was identified by partial digestion with trypsin and subsequent nano-electrospray ionisation-tandem mass spectrometry (nanoesi-ms/ms) analysis as an alpha(1)-antitrypsin. Western blot analysis, using an antibody against human alpha(1)-antitrypsin, revealed at least two bands, of molecular weight 58 kDa and ...
Factors concerning early embryonic death in thoroughbred mares in South Korea.
The Journal of veterinary medical science    September 11, 2007   Volume 69, Issue 8 787-792 doi: 10.1292/jvms.69.787
Yang YJ, Cho GJ.A total of 384 Thoroughbred mares were investigated to determine and evaluate the features of early embryonic death at nine equine farms on Jeju Island, South Korea, from 2001 to 2003. Overall, 771 matings for 384 mares resulted in 376 pregnancies 15 days after ovulation. Subsequently, 12.2% (46/376) of these early conceptuses were lost within 45 days after ovulation. Furthermore, about three quarters of the 46 embryonic deaths occurred between 16 and 25 days after ovulation. The incidence of embryonic death was highest in the barren (17.2%), more than 15 years old (15.4%), and more than 10 pa...
Molecular diagnosis of certain nematode infections can save life and beauty, and preserve breeds of socially relevant and sporting animals.
Veterinary parasitology    September 11, 2007   Volume 150, Issue 1-2 1-5 doi: 10.1016/j.vetpar.2007.08.011
Traversa D.The recognition that the health and welfare of some humans are improved through contact and relationships with animals is now established. Two commonly recognized assistance animals are dogs and horses. Both provide therapeutic benefits to humans with some physical and mental illnesses and both assist people with disabilities. Moreover, the public and scientific attention to the health and conservation of many animal breeds is also increasing worldwide. In the past few years, two potentially life-threatening nematode infections that can induce tumours or tumour-like masses in canids and equids...
Dose to persons assisting voluntarily during X-ray examinations of large animals.
Radiation protection dosimetry    September 11, 2007   Volume 128, Issue 3 274-278 doi: 10.1093/rpd/ncm422
Hupe O, Ankerhold U.Pet owners often assist voluntarily while their pets are being X-rayed during a medical examination. Medical staff members occupationally exposed to radiation are monitored regularly, as they wear personal dosemeters, whereas no dose measurements are carried out on voluntarily assisting persons, as measurements are both cost- and time-intensive. However, the dose limits prescribed in the German radiation protection regulations have to be observed for these volunteers as well. To assist the legislator in deciding whether the German regulation should be changed so that in future the dose of volu...
Repair of a Salter-Harris type II fracture of the calcaneus of a foal.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 350-352 doi: 10.1136/vr.161.10.350
Boado A, Clutton E, Booth TM.No abstract available
Atypical myopathy in two grazing horses in northern Spain.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 346-348 doi: 10.1136/vr.161.10.346
Palencia P, Rivero JL.No abstract available
Glossitis and tongue trauma subsequent to administration of an oral medication, using an udder infusion cannula, in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    September 11, 2007   Volume 48, Issue 8 845-847 
Fuller MC, Abutarbush SM.A 10-year-old gelding was presented with a tongue that had swelled immediately after oral administration of oxfendazole, using an udder infusion cannula. The tongue appeared to have been punctured inadvertently. The horse recovered after treatment with intravenous fluid, antibiotics, and anti-inflammatory drugs. Administering oral medication by this method should be discouraged. Un cheval hongre âgé de 10 ans a été présenté avec une langue devenue tuméfiée immédiatement après l’administration orale d’oxfendazole à l’aide d’une canule à infusion du pis. La langue semblait a...
Pharmacokinetics of acyclovir after intravenous infusion of acyclovir and after oral administration of acyclovir and its prodrug valacyclovir in healthy adult horses.
Antimicrobial agents and chemotherapy    September 10, 2007   Volume 51, Issue 12 4308-4314 doi: 10.1128/AAC.00116-07
Garré B, Shebany K, Gryspeerdt A, Baert K, van der Meulen K, Nauwynck H, Deprez P, De Backer P, Croubels S.The purpose of this study was twofold. The first aim was to evaluate the oral bioavailability and pharmacokinetics (PKs) of acyclovir in horses after intravenous (i.v.) administration and after oral administration of acyclovir and its prodrug, valacyclovir. Second, we aimed to combine these PK data with pharmacodynamic (PD) information, i.e., 50% effective concentrations (EC(50) values) from in vitro studies, to design an optimal dosage schedule. Three treatments were administered to healthy adult horses: 10 mg of acyclovir/kg of body weight delivered as an i.v. infusion over 1 h, 20 mg of acy...
Evaluation of the in vivo behaviour of gentamicin sulphate ocular mini-tablets in ponies.
Journal of veterinary pharmacology and therapeutics    September 7, 2007   Volume 30, Issue 5 470-476 doi: 10.1111/j.1365-2885.2007.00890.x
Gasthuys F, Pockelé K, Vervaet C, Weyenberg W, De Prijck K, Pille F, Vlaminck L, Nelis H, Remon JP.The in vivo behaviour of 5% gentamicin sulphate ocular mini-tablets (2-mm diameter, 6.525 mg weight) was compared with gentamicin eye drops in six ponies. Two mini-tablets were inserted on the bulbar conjunctiva of the right eye while a similar dose of gentamicin was administered via eye drops in the left eye. Irritation induced by the mini-tablets and the eye drops was evaluated using a visual analogue scale (0-10). Tears were sampled with ophthalmologic absorption triangles for 1 min for the determination of the concentration of gentamicin sulphate using a microbiological plate diffusion met...
Equine recurrent airway obstruction does not alter airway muscarinic acetylcholine receptor expression and subtype distribution.
Journal of veterinary pharmacology and therapeutics    September 7, 2007   Volume 30, Issue 5 401-409 doi: 10.1111/j.1365-2885.2007.00897.x
Abraham G, Kottke C, Ungemach FR.In recurrent airway obstruction (RAO) or heaves, bronchospasm has been attributed to enhanced cholinergic activity. However, the expression and function of muscarinic acetylcholine receptors (mAChR) and their signaling components are not yet known. Thus, we examined the expression, subtype distribution and postreceptor signaling pathways of mAChR in the peripheral lung, bronchial and tracheal epithelia with the underlying smooth muscle from nine horses with RAO and 11 healthy control horses. In RAO horses, no significant segment-dependent alteration in mAChR density and subtype distribution (a...
Some pharmacodynamic effects of eformoterol in the horse.
Journal of veterinary pharmacology and therapeutics    September 7, 2007   Volume 30, Issue 5 496-499 doi: 10.1111/j.1365-2885.2007.00882.x
Ladaga GJ, Lezica FP, Ferraro G, De Erausquin GA.No abstract available
Pelger-Huët anomaly in an Arabian horse.
Veterinary clinical pathology    September 7, 2007   Volume 36, Issue 3 306-310 doi: 10.1111/j.1939-165x.2007.tb00231.x
Grondin TM, DeWitt SF, Keeton KS.A 9-year-old Arabian mare was evaluated for a 7-day history of malaise. Results of a CBC included a leukocyte concentration within the reference interval (8.4 x 10(3)/microL, reference interval 6.0-14.0 x 10(3)/microL) with an apparent degenerative left shift (segmented neutrophils 1.2 x 10(3)/microL, reference interval 2.5-7.5 x 10(3)/microL; hyposegmented neutrophils 1.8 x 10(3)/microL, reference interval 0.0-0.2 x 10(3)/microL). Serum clinical chemistry results included increased aspartate transaminase, alkaline phosphatase, and gamma-glutamyltransferase activities. A presumptive diagnosis ...
Risk factors for influenza infection in vaccinated racehorses: lessons from an outbreak in Newmarket, UK in 2003.
Vaccine    September 6, 2007   Volume 25, Issue 43 7520-7529 doi: 10.1016/j.vaccine.2007.08.038
Barquero N, Daly JM, Newton JR.Between March and May 2003, clinical equine influenza was confirmed among vaccinated racehorses in Newmarket, UK. A particular feature was that 2-year-old horses were apparently less susceptible than older animals. Statistical analyses comparing infected and non-infected animals showed the unusual, apparently counter-intuitive inverse age effect was principally explained by more recent vaccination among younger animals, despite broadly equivalent antibody levels between age groups. There was novel evidence for sexual dimorphism in susceptibility to infection and data supported the hypothesis t...