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Topic:Infection

Infections in horses encompass a range of diseases caused by various pathogens, including bacteria, viruses, fungi, and parasites. These infections can affect different systems within the horse, such as the respiratory, gastrointestinal, and integumentary systems, leading to a variety of clinical signs depending on the pathogen and the severity of the infection. Common infectious diseases in horses include equine influenza, strangles, and equine herpesvirus. Diagnosis often involves clinical examination, laboratory testing, and sometimes imaging, to identify the causative agent and assess the extent of the disease. Treatment strategies may include antimicrobial therapy, supportive care, and preventive measures such as vaccination and biosecurity practices. This page aggregates peer-reviewed research studies and scholarly articles that explore the pathogenesis, diagnosis, treatment, and prevention of infectious diseases in equine populations.
Direct Isolation of Pasteurella-Like Microorganisms from Brains of Horses Suffering from So-Called Cornstalk Disease.
Science (New York, N.Y.)    April 19, 1935   Volume 81, Issue 2103 387-388 doi: 10.1126/science.81.2103.387-a
Graham R.No abstract available
A Pasteurella-Like Microorganism in the Brains of Horses Suffering from So-Called Cornstalk Disease.
Science (New York, N.Y.)    February 8, 1935   Volume 81, Issue 2093 153-154 doi: 10.1126/science.81.2093.153
Graham R.No abstract available
Histological Changes in the Central Nervous System Following Equine Encephalomyelitis.
The American journal of pathology    May 1, 1934   Volume 10, Issue 3 361-374.3 doi: 10.1097/00005053-193501000-00028
Larsell O, Haring CM, Meyer KF.No abstract available
The Histology of Equine Encephalomyelitis.
The Journal of experimental medicine    April 30, 1934   Volume 59, Issue 5 529-542 doi: 10.1084/jem.59.5.529
Hurst EW.The virus of equine encephalomyelitis (eastern strain) evokes in the horse, calf, sheep and dog an unusually intense encephalomyelitis characterized by acute primary degeneration of nerve cells, the appearance in neurons of the brain stem and elsewhere of nuclear inclusions resembling those in Borna disease and poliomyelitis, polymorphonuclear infiltration in the nervous tissues with early microglial proliferation, and perivascular cuffing with mononuclears and polymorphonuclears in varying proportions. The grey matter is affected more than the white. Lesions may be less marked in the striatum...
COMPARATIVE STUDIES ON THE VIRUSES OF VESICULAR STOMATITIS AND EQUINE ENCEPHALOMYELITIS (1).
The Journal of experimental medicine    January 31, 1934   Volume 59, Issue 2 159-171 doi: 10.1084/jem.59.2.159
Olitsky PK, Cox HR, Syverton JT.We have studied certain properties, additional to those previously described (3), of the virus of vesicular stomatitis of horses, and of the characteristic biological reactions of the virus of equine encephalomyelitis. It has been found that the virus of stomatitis, ordinarily dermotropic, can acquire neurotropism and the neurotropic encephalomyelitis virus can, in turn, be rendered dermotropic in its action. The neurotropism in both instances is associated with definite, although not pronounced, viscerotropism. Both viruses can bring about a similar infection in the white mouse, rat, guinea p...
Relationship of the Viruses of Vesicular Stomatitis and of Equine Encephalomyelitis.
Science (New York, N.Y.)    September 8, 1933   Volume 78, Issue 2019 216-217 doi: 10.1126/science.78.2019.216
Syverton JT, Cox HR, Olitsky PK.No abstract available
Respiratory Infection in Equine Encephalomyelitis.
Science (New York, N.Y.)    July 14, 1933   Volume 78, Issue 2011 41-42 doi: 10.1126/science.78.2011.41
Vawter LR, Records E.No abstract available
THE ETIOLOGY OF EPIZOOTIC ENCEPHALOMYELITIS OF HORSES IN THE SAN JOAQUIN VALLEY, 1930.
Science (New York, N.Y.)    August 28, 1931   Volume 74, Issue 1913 227-228 doi: 10.1126/science.74.1913.227
Meyer KF, Haring CM, Howitt B.No abstract available
The Relationship of the Flavobacterium Ophthalmiae to Periodic Ophthalmia in Horses.
Transactions of the American Ophthalmological Society    January 1, 1929   Volume 27 131-148 
Woods AC, Burky EL.No abstract available
EFFECT OF FORMALIN ON THE VIRUS OF VESICULAR STOMATITIS OF HORSES.
The Journal of experimental medicine    May 31, 1928   Volume 47, Issue 6 835-841 doi: 10.1084/jem.47.6.835
Olitsky PK, Long PH.The virus of vesicular stomatitis is not readily killed by formalin. This chemical is one of a group which coagulates the proteins of the medium in which the virus is usually contained. It has already been found(7) that other reagents of the protein-coagulating group are not actively virucidal) and the effect of formalin in this instance is therefore characteristic of the group. The so called formalinized vaccines which give rise to immunity can be shown to have done so because of the presence of living virus. A single injection of such so called "vaccine," or of other material containing livi...
The Precipitin Reaction of Antipneumococcus Sera: II. The Ratio of Precipitin to Protective Antibody.
The Journal of experimental medicine    January 1, 1928   Volume 47, Issue 1 79-89 doi: 10.1084/jem.47.1.79
Friedlander M, Sobotka H, Banzhaf EJ.The precipitin indices for a number of monovalent and polyvalent antipneumococcus sera were determined under known conditions, and found to vary as did the number of protective units. The ratio precipitin index/protective units in monovalent sera was found to lie between 2.8 and 4.8 for Type I and to be about ten times greater for Type III. Lower values were found in polyvalent horses and when mixing heterologous monovalent sera with each other. The influence of the duration of treatment upon the quotient was studied. Several refined and concentrated preparations showed a relative increase in ...
A Study of Pneumococci Isolated from Horses Undergoing Pneumococcus Immunization.
The Journal of experimental medicine    April 30, 1927   Volume 45, Issue 5 787-797 doi: 10.1084/jem.45.5.787
Wadsworth AB, Sickles GM.IT HAS BEEN SHOWN THAT THE PNEUMOCOCCUS MULTIPLYING IN THE TISSUES OF THE IMMUNIZED ANIMAL (HORSE) BECOMES ATTENUATED: loses, in varying degrees, its virulence, capacity of capsule formation, susceptibility to phagocytosis, and type specificity. The antigenic activity as an immunizing agent and the production of "soluble specific substance" are also altered. In some instances, the typical pneumococcus characteristics may be quickly restored by one or two passages through a susceptible animal (mouse). In others, virulence is not recovered and the organism remains atypical. Whether these changes...
The Occurrence of Degraded Pneumococci in Vivo.
The Journal of experimental medicine    April 30, 1927   Volume 45, Issue 5 807-814 doi: 10.1084/jem.45.5.807
Reimann HA.It is conceivable that a change from the virulent, non-phagocytable S form of Pneumococcus to the avirulent phagocytable R form may take place in pneumococcus disease, but the experiments here reported do not settle the question whether or not this is an important factor in determining the outcome in natural infection. It has been shown experimentally that the degradation from the S form to the R form actually does take place in cultures of Pneumococcus growing in agar subcutaneously embedded in guinea pigs, in agar enclosed in vials subcutaneously embedded in rabbits, and spontaneously in the...
A Specific Flocculation Reaction Occurring Between Alcoholic Extracts of Pneumococci and Antipneumococcus Serum.
The Journal of experimental medicine    January 31, 1927   Volume 45, Issue 2 227-241 doi: 10.1084/jem.45.2.227
Jungeblut CW.1. A flocculation reaction has been described which occurs between alcoholic extracts of pneumococci and antipneumococcus serum. 2. The reaction appears to be species-specific. It is not strictly type-specific, as slight or moderate cross-reactions occurred between Type I serums and Type II and Type III extracts. 3. The flocculating power of the serum from five horses undergoing immunization with pneumococcus, Type I, did not develop to any extent before the end of the 4th or 5th month. 4. In the case of two of these horses in which it was possible to carry out parallel tests on a larger numbe...
Analogies between Influenza of Horses and Influenza of Man.
Proceedings of the Royal Society of Medicine    January 1, 1924   Volume 17, Issue Sect Epidemiol State Med 47-58 
Williams AJ.No abstract available
Toxins and Antitoxins of Bacillus Dysenteriae Shiga.
The Journal of experimental medicine    January 1, 1920   Volume 31, Issue 1 19-33 doi: 10.1084/jem.31.1.19
Olitsky PK, Kligler IJ.With the methods which have been described we have separated an exotoxin and an endotoxin from cultures of the Shiga dysenteric bacillus. The study of the nature and effect of the poison of this microorganism is thus simplified. The two toxins are physically and biologically distinct. The exotoxin is relatively heat-labile, arises in the early period of growth, and yields an antiexotoxic immune serum. The endotoxin, on the other hand, is heat-stable, is formed in the later period of growth, and is not neutralized by the antiexotoxic serum. The exotoxin exhibits a specific affinity for the cent...
The Streptococci of Equines.
The Journal of experimental medicine    August 1, 1919   Volume 30, Issue 2 159-178 doi: 10.1084/jem.30.2.159
Jones FS.The lower nasal mucosa and the pharynx of thirty eastern and twenty-three western horses have been examined for streptococci. Eight of the eastern horses carried non-hemolytic streptococci on the nasal mucosa. From the pharynx of six, non-hepiolytic streptococci were cultivated. The throats of eighteen contained strains of the hemolytic type. The nasal mucosa of the eastern horses failed to show hemolytic streptococci. Eight western horses carried non-hemolytic streptococci in the nasal passage; eight also harbored the hemolytic type. Twenty-two strains were isolated from the pharynx. Eleven w...
A Study of the Endocardial Lesions developing during Pneumococcus Infection in Horses.
The Journal of medical research    January 1, 1919   Volume 39, Issue 3 279-292.11 
Wadsworth AB.No abstract available
Studies in Forage Poisoning: The Relation of B. botulinus to Forage Poisoning or Cerebrospinal Meningitis in Horses.
Journal of bacteriology    January 1, 1919   Volume 4, Issue 1 1-21 doi: 10.1128/jb.4.1.1-21.1919
Graham R, Brueckner AL.No abstract available
STANDARDIZATION OF ANTIMENINGOCOCCIC SERUM.
The Journal of experimental medicine    November 30, 1918   Volume 28, Issue 6 779-790 doi: 10.1084/jem.28.6.779
Amoss HL, Marsh P.Experiments were made for the purpose of testing the reaction of protection against infection as a measure of potency of antimeningococcic serum. The results of the experiments were extremely variable and bore no relation to the quality of the sera as determined by the period of immunization of the horses from which they were obtained, or the indications of efficiency based upon their employment in human cases of epidemic meningitis. The results also failed entirely to conform to the agglutination titer of the sera tested and to be affected by the different type forms of the meningococci. We r...
The Serum Treatment of Weil’s Disease (Spirochaetosis Icterohaemorrhagica).
The Journal of experimental medicine    November 1, 1916   Volume 24, Issue 5 485-496 doi: 10.1084/jem.24.5.485
Inada R, Ido Y, Hoki R, Ito H, Wani H.Horses immunized with cultures of Spirochaeta icterohaemorrhagiae yield an immune serum having therapeutic properties. With rare exceptions the serum destroys completely the spirochetes contained in the circulating blood. The development of antibodies is promoted by the serum injections. The number of spirochetes in the organs is reduced by the treatment. Secondary manifestations due to the serum are slight and disappear promptly. The ultimate effects of the serum treatment on the symptoms and final outcome of the disease have still to be determined.
DENTAL SEPSIS.
British medical journal    June 6, 1914   Volume 1, Issue 2788 1244-1248 doi: 10.1136/bmj.1.2788.1244-a
Turner JG.No abstract available
The Swamp Fever of Horses.
The Journal of medical research    June 1, 1911   Volume 24, Issue 3 213-242 doi: 10.5962/bhl.title.101893
Todd JL, Wolbach SB.No abstract available
Hemorrhagic Hepatitis in Antitoxin Horses.
The Journal of medical research    December 1, 1906   Volume 15, Issue 3 449-468.1 
Lewis PA.No abstract available
Equine Piroplasmosis, or “Biliary Fever”.
The Journal of hygiene    January 1, 1905   Volume 5, Issue 1 7-17 doi: 10.1017/s0022172400002321
Bowhill T.No abstract available
Acute Pleurisy in Horses.
The Journal of comparative medicine and veterinary archives    May 1, 1903   Volume 24, Issue 5 281-284 
Baker AH.No abstract available
Acute Epizootic Leucoencephalitis in Horses.
The Journal of experimental medicine    November 1, 1901   Volume 6, Issue 1 65-74 doi: 10.1084/jem.6.1.65
Maccallum WG, Buckley SS.No abstract available
Horses in the Boer War.
The Journal of comparative medicine and veterinary archives    July 1, 1901   Volume 22, Issue 7 464-472 
No abstract available
The Fractional Precipitation of the Globulin and Albumin of Normal Horse’s Serum and Diphtheria Antitoxic Serum, and the Antitoxic Strength of the Precipitates.
The Journal of experimental medicine    October 1, 1900   Volume 5, Issue 1 67-76 doi: 10.1084/jem.5.1.67
Atkinson JP.1. The globulins of both normal and diphtheria antitoxic serum exhibit chemically toward reagents the same reactions, being precipitated by magnesium sulphate and split up into fractions in precisely the same way. 2. All of the diphtheric antitoxic power of both normal and immunized serum is always carried by the globulin and its fractional precipitates. 3. During the fractional precipitation of the serum globulin of horses immunized from diphtheria toxin and horses not immunized from diphtheria toxin, some of the globulin is lost, likewise at the same time some of the antitoxic power of the g...
Epizootic Cellulitis among Horses.
The Journal of comparative medicine and veterinary archives    August 1, 1899   Volume 20, Issue 8 511-512 
Manley .No abstract available