Iron is an essential trace mineral in horses that plays a significant role in various physiological processes, including oxygen transport, energy metabolism, and enzyme function. It is a key component of hemoglobin and myoglobin, proteins responsible for transporting oxygen in the blood and muscles, respectively. Iron is also involved in the function of certain enzymes and the synthesis of DNA. Horses typically obtain iron from their diet, with forages and grains being primary sources. However, both iron deficiency and overload can lead to health issues, such as anemia or hemosiderosis. This page compiles peer-reviewed research studies and scholarly articles that explore the metabolism, dietary requirements, and health implications of iron in equine physiology.
LUDEWIG S.1. A method is outlined for isolating hemosiderin from horse spleen by sedimentation from salt solutions of different specific gravities. 2. The iron, nitrogen, phosphorus and ash concentration varied considerably in hemosiderin samples obtained from different spleens. Fractionation of these preparations by sedimentation in organic liquids showed that fractions could be obtained which varied in their iron concentrations from about 25 to 41% iron. 3. Hemosiderin has been found to contain hexoseamine, galactose, mannose and fucose.
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JENNINGS FW, MULLIGAN W.THE chemical analyses reported in this paper arc the result of an investigation on the sera of thirty normal horses from a heavy draught horse stable in Glasgow. Determinations have been made of scrum proteins (albumin and total globulin), alkaline phosphatase, bilirubin, calcium, magnesium, inorganic phosphate and urea. Estimations of some of these constituents have already been carried out by a number of workers, but in the majority of cases the investigation has been confined to one or two constituents relevant to the problem being studied, and many of the data available are a by-product of...
The type of diet that a horse consumes is one of the most important factors determining the mineral profile and tensile strength of its hooves, so the quality and nutritional value of the supplied feed are fundamental to achieving satisfactory hoof quality. The objective of this study was to compare the differences in the mineral concentrations of sodium (Na), potassium (K), magnesium (Mg), zinc (Zn), and Iron (Fe) between two diets, namely silage and a commercial concentrate, using atomic absorption spectrometry and to determine which led to higher increases in the hoof tensile strength of ho...
Son V, Penagos-Tabares F, Hollmann M, Khiaosa-Ard R, Sulyok M, Krska R, Zebeli Q.Pastures are used for grazing and the production of conserved roughage in horses. Yet, the nutritional profile of the forage varies from spring to late summer, affecting equine nutrient supply and health. In addition, environmental factors may also favor plant contaminants such as mycotoxins. This study aimed to determine the nutritional profile and contaminant load of selected horse pastures from early spring till late summer. The nutrient composition (main macronutrients, macro elements and trace elements), as well as mycotoxins, metabolites, pesticides, and plant-derived compounds of seven ...
Canola PA, Salles RF, Daneze ER, Sobreira MFR, Oliveira BE, Favero ML, Antonioli ML.The aim of the study was to compare and correlate levels of ferritin, transferrin, iron and APPs in healthy horses and those surgically treated for strangulating colic. On admission, measurements of inflammatory markers related to iron and total protein, fibrinogen, albumin, haptoglobin and ceruloplasmin were made. The study comprised 22 horses, divided into a control group (CG) of healthy horses (n = 10) and horses with surgically treated acute abdomen (n = 12), obstruction group (OG). The OG was subdivided according to the affected intestinal segment (small vs. large) and according to ou...
Giers J, Bartel A, Kirsch K, Müller SF, Horstmann S, Gehlen H.After submaximal exercise, blood values of eventing horses show physiological reactions. This prospective longitudinal study investigated blood parameters in 20 elite eventing horses before and after two-four-star cross-country rides. Using a mixed model adjusting for plasma volume shift, we assessed exercise-dependent parameters and compared blood values with reference ranges for healthy horses at rest. Following exercise, cortisol, triiodothyronine (T3) and thyroxine (T4) showed short-term increases, and superoxide-dismutase showed a small short-term increase. Hepatic values showed short-ter...
Su Y, Zhang Z, Wang L, Zhang B, Su L. subsp. () is one of the important zoonotic and opportunistic pathogens. In recent years, there has been growing evidence that supports the potential role of in severe diseases in horses and other animals, including humans. Furthermore, the clinical isolation and drug resistance rates of have been increasing yearly, leading to interest in its in-depth genomic analysis. In order to deepen the understanding of the characteristics and genomic features, we investigated the genomic islands, mobile genetic elements, virulence and resistance genes, and phenotype of strain ZHZ 211 (ST147), isolat...
Aragona F, Giannetto C, Piccione G, Licata P, Deniz Ö, Fazio F.The aim of the present study was the evaluation of the bioaccumulation of cadmium (Cd), Zinc (Zn), Chrome (Cr), Lead (Pb), Iron (Fe) and Copper (Cu), in the blood, serum, tail and mane of horses from the industrialized area of Milazzo (Messina, Sicily), to understand the relationships between haematological parameters: Red Blood Cells (RBCs), White Blood Cells (WBCs), Haemoglobin (Hb), Haematocrit (Hct), Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), Mean Corpuscular Haemoglobin Concentration (MCHC), Platelets (PLTs) and the concentrations of trace elements. Blood and hair ...
Halo M, Kirchner R, Tirpák F, Slanina T, Tokárová K, Kováčik A, Miškeje M, Greń A, Formicki G, Halo M, Madeddu R, Massányi P.The abundance of chemical elements in the blood of horses can indicate the physiological balance, health of animal as well as can be taken as an indicator of environmental pollution. The aim of this work was to analyse haematological, biochemical parameters, TOS, FRAP, SOD, Gpx, TAS and their correlations with concentrations of essential and risk elements in blood of horses stabled in two different locations: The National Stud Farm Topoľčianky (n = 11; 11 stallions, consisting of the breeds 6 Lipizzan, 3 Slovak warmblood, 2 Holsteiner) and Experimental Centre at Institute of Animal Husba...
Hisaeda K, Ono T, Shimokawa-Miyama T, Hata A, Iwata E, Hiasa Y, Ohzawa E, Tozaki T, Murase H, Takasu M, Nishii N, Kitagawa H.We examined the differences in serum iron (Fe) concentrations and related variables between summer and winter in Noma horses. Blood samples were collected from 37 clinically normal horses seven consecutive times: September 2018, February 2019, October 2019, February 2020, September 2020, February 2021, and February 2022. Serum Fe concentrations ranged from 74 μg/dl to 316 μg/dl with a median of 176 μg/dl. The concentrations were lower in stallions compared with mares and geldings, tended to be low at 10-14 years of age, and then increased with age. Serum Fe concentrations were repeatedly lo...
Midon M, Clark-Price SC, Lin HC, Lascola KM, Boone L.To determine if serum iron concentrations decrease acutely during and after general anesthesia in healthy horses. Methods: Prospective experimental study. Methods: A convenience sample of 24 healthy adult horses (eight females, 16 geldings), weighing 545 ± 33 kg (mean ± standard deviation). Methods: Horses were anesthetized for 120 minutes with isoflurane, after premedication with intravenous (IV) xylazine (0.8 mg kg-1) and induction with IV midazolam (0.1 mg kg-1) and ketamine (2.2 mg kg-1). Blood samples for serum iron analysis were obtained just before premedication (baseline), after 60 m...
Kiełbik P, Witkowska-Piłaszewicz O.Iron is unquestionably an essential element of physical performance for horses, just as it is for many other animals, including humans. Although post-exercise equine iron deficiency is not a common problem, recent studies showed that equine athletes may be considered a model for human exercise physiology. Sports anemia among human athletes is a common nutritional issue and remains one reason for poor physical fitness. Thus, this study area needs comprehensive knowledge since iron homeostasis changes in equine athletes remain unrecognized. The current review aims to summarize studies describing...
