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Topic:Medical Treatment

Medical treatment in horses encompasses a wide range of therapeutic interventions aimed at maintaining or restoring equine health. It includes the administration of pharmaceuticals, surgical procedures, and alternative therapies to address various health conditions in horses. Common medical treatments involve the use of anti-inflammatory drugs, antibiotics, and dewormers, as well as vaccines to prevent infectious diseases. Surgical interventions may be necessary for conditions such as colic or orthopedic injuries. Additionally, complementary therapies, such as physiotherapy and acupuncture, are sometimes employed to support recovery and enhance well-being. This page aggregates peer-reviewed studies and scholarly articles that explore the methodologies, efficacy, and outcomes of different medical treatments in equine medicine.
Intrahepatic mucinous cholangiocarcinoma with recurrent colic in a horse: case report and literature review of cholangiocarcinoma in horses. Barrantes Murillo DF, Cattley RC, Cullen JM, Withers C, Towns J, Pfeifle R, Wooldridge A, Neto RLALT.A 17-y-old Arabian mare was presented to the Auburn Large Animal Veterinary Teaching Hospital with a long-term history of intermittent mild recurrent colic that responded to medical treatment. CBC revealed mild lymphopenia; serum biochemistry findings were of increased gamma-glutamyl transferase and creatine kinase activities, hyperferremia, hyperglycemia, hypomagnesemia, and hypokalemia. Abdominocentesis was compatible with low-protein transudate. Due to the progression and duration of clinical signs, the owner elected euthanasia. Postmortem examination and histopathology confirmed a cholangi...
Splenic hematoma and hemoperitoneum in a Thoroughbred racehorse after racing.
Journal of the American Veterinary Medical Association    April 5, 2024   1-3 doi: 10.2460/javma.24.01.0011
Neville E, Pigott J.To describe the clinical presentation of a Thoroughbred filly with acute hemoperitoneum from a splenic source immediately after racing. Methods: A 3-year-old Thoroughbred filly used for racing and that had raced shortly before presentation to the hospital. Unassigned: On presentation, the filly was quiet, alert, and responsive with a heart rate of 76 beats/min, pale mucous membranes, and absent borborygmi. All other physical examination parameters were within normal limits. Abdominal ultrasound was performed and revealed echogenic free abdominal fluid and a splenic hematoma. Abdominocentesis y...
Small Colon Faecalith with Large Colon Displacement in Ten Cases (2015-2023): A Detailed Case Description and Literature Review.
Animals : an open access journal from MDPI    January 15, 2024   Volume 14, Issue 2 doi: 10.3390/ani14020262
Scilimati N, Cerullo A, Nannarone S, Gialletti R, Giusto G, Bertoletti A.Small colon impaction can result in accumulation of ingesta, gas, and fluid orally to the impaction site in horses. Large colon tympany, which is caused by ingesta fermentation, can be a predisposing factor for intestinal displacement. The aim of this study is to report the history, clinical, and surgical findings of horses and ponies referred for abdominal pain not responsive to drugs where a right dorsal displacement (RDD) or large colon volvulus (LCV), together with a small colon faecalith (SCF), were diagnosed during surgery. This study included a total of five horses and five ponies. Base...
Subconjunctival autologous muscle-derived mesenchymal stem cell therapy: A novel, minimally invasive approach for treating equine immune-mediated keratitis.
Veterinary ophthalmology    December 10, 2023   doi: 10.1111/vop.13175
Narinx F, Sauvage A, Ceusters J, Grulke S, Serteyn D, Monclin S.To establish the safety of subconjunctival injections of autologous muscle-derived mesenchymal stem cells (mdMSCs) in healthy horses and to evaluate their effect in four horses (six eyes) with severe chronic equine immune-mediated keratitis (IMMK) that was unresponsive to medical treatments. Methods: MdMSCs were cultured from minimally invasive muscle biopsies. In the safety group, four healthy horses received two subconjunctival injections of 2.5 and 5 million cells, respectively, at 1-month interval, to the same eye. Ocular side effects were monitored for 1 month following each injection. ...
Pain scoring systems in hospitalized horses with ocular disease.
Journal of veterinary internal medicine    November 19, 2023   doi: 10.1111/jvim.16933
Jodzio D, DeNotta S, Plummer C, Sanchez C.Pain recognition in hospitalized horses is challenging, and the utility of pain scoring systems in horses with ocular disease has not been well-described. Objective: Evaluate the horse grimace scale (HGS) and behavior pain score (BPS) in hospitalized horses with ocular disease. We hypothesized that HGS and BPS would be associated with different clinical progressions. Methods: Privately owned horses hospitalized for ocular disease between September 2018 and September 2020. Methods: Retrospective observational study. The HGS and BPS were recorded daily throughout hospitalization. Clinical progre...
Integrative Medicine: What Is it Good for?
The Veterinary clinics of North America. Equine practice    October 13, 2022   Volume 38, Issue 3 xi-xii doi: 10.1016/j.cveq.2022.06.002
Haussler KK.No abstract available
Short-term survival rates of 1397 horses referred for colic from 2010 to 2018.
Acta veterinaria Scandinavica    May 7, 2022   Volume 64, Issue 1 11 doi: 10.1186/s13028-022-00631-4
Dybkjær E, Steffensen KF, Honoré ML, Dinesen MA, Christophersen MT, Pihl TH.Up-to-date and hospital-specific knowledge of prognoses for horses with various forms of colic is essential for helping to guide owners' decisions on costly treatments, and for assessing the continuous development of standards of care in the hospital. This study aimed to determine the short-term survival rates of horses admitted with colic to the University Hospital for Large Animals (UHLA), University of Copenhagen, Denmark, from 2010 to 2018, and to compare these to a previous local study as well as recent, comparable international studies. Short-term survival rates were calculated for horse...
Effects of xylazine and adrenaline combinations: Preliminary clinical application for non-surgical protocols of nephrosplenic entrapment in horses.
Veterinary world    December 28, 2021   Volume 14, Issue 12 3188-3193 doi: 10.14202/vetworld.2021.3188-3193
Cherdchutham W, Sukhong P, Sae-Oueng K, Supanwinijkul N, Wiangnak K, Srimuang J, Apichaimongkonkun T, Limratchapong S, Petchdee S.The medical treatment of horses with nephrosplenic entrapment (NSE) of the large colon through administrating phenylephrine and rolling during general anesthesia was effective and less expensive than surgical treatment. However, the selection of drugs for non-surgical treatment of NSE is not a usual method for clinical practice. This study aimed to identify the effects of combined drugs on the cardiac and splenic response in horses and provide information on the NSE of the large colon for clinical application. Methods: Six healthy Thai native crossbred horses were enrolled in this study. Horse...
Complications and Comorbidities in Foals Undergoing Surgical Repair for Uroperitoneum.
Journal of equine veterinary science    December 24, 2021   Volume 110 103852 doi: 10.1016/j.jevs.2021.103852
Ford MG, Nelson BB, Ford TS, Souza CRS, Easley JT, Hackett ES.Surgical repair is frequently effective at resolving uroperitoneum in foals, though complications occur. Despite their occurrence, management strategies used to address these complications, and their impact on survival are not clearly defined. To better describe the complications following surgical correction of uroperitoneum and to document treatment strategies and outcomes after intervention, a multi-center retrospective case series was performed. Medical record data of foals undergoing surgical treatment for uroperitoneum were retrieved from three surgical centers, and cases identified with...
Use of saline contrast ultrasonography in the diagnosis of complete jugular vein occlusion in a horse.
Open veterinary journal    September 15, 2020   Volume 10, Issue 3 308-316 doi: 10.4314/ovj.v10i3.9
Corda A, Columbano N, Secchi V, Scanu A, Parpaglia MLP, Careddu GM, Passino ES.Thrombophlebitis and thrombosis are the most common causes of jugular vein occlusion in horses. Medical and surgical treatments aim to recanalize the occluded vessel and reduce proximal venous congestion and edema. The present report describes a clinical case of equine jugular vein thrombosis (JVT) with complete vein occlusion diagnosed by saline contrast ultrasonography (SCU) and confirmed by contrast venography. Our results demonstrated that the SCU test can be easily performed and objectively interpreted using standard ultrasound equipment; it is not expensive and it does not require x-ray...
Career outcome of Thoroughbred racehorses with metacarpo/metatarsophalangeal joint dorsal chip fracture managed nonsurgically and surgically: A retrospective cohort study.
Equine veterinary journal    April 17, 2020   Volume 52, Issue 6 823-831 doi: 10.1111/evj.13253
Ramzan PHL, Wylie CE.Arthroscopy has been advocated as the treatment of choice for dorsal osteochondral chip fracture of the metacarpo/metatarsophalangeal (MCP/MTP) joint. However, there is no published research on racing performance outcomes of horses with this pathology managed nonsurgically. Objective: To compare racing career outcomes of Thoroughbred racehorses with nonsurgically (non-SX) or surgically (SX) managed MCP/MTP dorsal osteochondral chip fracture alongside a cohort of horses with no dorsal osteochondral chip fracture (unexposed). Methods: Retrospective cohort study conducted between 2006 and 2014. M...
Idiopathic peritonitis in horses: a retrospective study of 130 cases in Sweden (2002-2017).
Acta veterinaria Scandinavica    April 25, 2019   Volume 61, Issue 1 18 doi: 10.1186/s13028-019-0456-2
Odelros E, Kendall A, Hedberg-Alm Y, Pringle J.Peritonitis in horses is historically associated with prolonged treatment regimens of broad-spectrum antimicrobials and a guarded prognosis for survival. The condition is most often seen as a secondary complication to traumatic injuries involving the abdominal cavity, rupture of bowel or abdominal surgery. However, cases of idiopathic peritonitis with no such underlying cause have been described. In Sweden idiopathic peritonitis is commonly identified and, in contrast to peritonitis secondary to traumatic incidents, affected horses appear to respond well to medical treatment. The objectives of...
Neck, Back, and Pelvic Pain in Sport Horses.
The Veterinary clinics of North America. Equine practice    May 28, 2018   Volume 34, Issue 2 235-251 doi: 10.1016/j.cveq.2018.04.002
García-López JM.Pain localized to the neck, back, and or pelvis can result in a profound effect on the horse's performance. These conditions can present with a varied and nonspecific set of clinical signs. A careful and thorough examination of these areas by means of physical examination, lameness evaluation both in hand and under saddle, diagnostic anesthesia, and the use of multiple imaging modalities in combination is often necessary to have an accurate prognosis. Medical and surgical management where appropriate of the conditions highlighted in this article are discussed as well as their individual progno...
Medical treatment of horses with deep digital flexor tendon injuries diagnosed with high-field-strength magnetic resonance imaging: 118 cases (2000-2010).
Journal of the American Veterinary Medical Association    November 26, 2015   Volume 247, Issue 11 1309-1318 doi: 10.2460/javma.247.11.1309
Lutter JD, Schneider RK, Sampson SN, Cary JA, Roberts GD, Vahl CI.To describe the location and severity of deep digital flexor tendon (DDFT) lesions diagnosed by means of high-field-strength MRI in horses and to identify variables associated with return to activity following medical treatment. Methods: Retrospective case series. Methods: 118 horses. Methods: Medical records of horses with DDFT injury diagnosed with MRI over a 10-year period (2000-2010) and treated medically (intrasynovial administration of corticosteroids and sodium hyaluronan, rest and rehabilitation, or both) were reviewed. History, signalment, use, results of lameness examination and diag...
Comparison of surgical and medical treatment of 49 postpartum mares with presumptive or confirmed uterine tears.
Veterinary surgery : VS    March 10, 2010   Volume 39, Issue 2 254-260 doi: 10.1111/j.1532-950X.2010.00645.x
Javsicas LH, Giguère S, Freeman DE, Rodgerson DH, Slovis NM.To determine outcome after medical or surgical treatment of postpartum mares with confirmed or presumptive uterine tears. Methods: Case series. Methods: Postpartum mares were included if foaling had occurred within 7 days and uterine tear was confirmed surgically or, in medically treated mares, by palpation or presumed based on peritonitis. Information (age, breed; physical examination, laboratory and abdominocentesis findings; treatment, survival rates, length of hospital stay, treatments costs, and breeding performance after discharge) was obtained from the medical records (1990-2007). The i...
Superovulation in mares.
Animal reproduction science    June 12, 2006   Volume 99, Issue 1-2 1-8 doi: 10.1016/j.anireprosci.2006.04.054
Squires EL, McCue PM.Embryo recovery from single ovulating mares is approximately 50 per cent per estrous cycle. Superovulation could be used to increase embryo recovery and provide extra embryos for embryo freezing. This review addresses some historical approaches to superovulation, as well as examines factors that affect the response of mares to equine FSH. eCG, GnRH and inhibin vaccines have been of limited success in stimulating multiple ovulation. Numerous studies have shown that injection of equine pituitary extract (EPE) will result in three to four ovulations per estrous cycle and two embryos. A purified, ...
Harnessing the stem cell for the treatment of tendon injuries: heralding a new dawn?
British journal of sports medicine    August 25, 2005   Volume 39, Issue 9 582-584 doi: 10.1136/bjsm.2005.015834
Smith RK, Webbon PM.No abstract available
Abdominal radiography in monitoring the resolution of sand accumulations from the large colon of horses treated medically.
Equine veterinary journal    February 24, 2001   Volume 33, Issue 1 59-64 doi: 10.2746/042516401776767403
Ruohoniemi M, Kaikkonen R, Raekallio M, Luukkanen L.This retrospective study consisted of 14 horses (age 6 weeks-12 years) with radiographically evident sand accumulations cranioventrally in the abdomen and clinical signs suggestive of sand enteropathy. The horses were treated medically and resolution of sand was monitored radiographically. Routine treatment consisted of psyllium mucilloid, combined with magnesium sulphate and/or mineral oilif needed. Initially, the number, size and shape of the sand accumulations showed large variation and the response to therapy was not predictable based on the initial appearance of the accumulation. In 2 foa...
Medical treatment of cholangiohepatitis and cholelithiasis in mature horses: 9 cases (1991-1998).
Equine veterinary journal    August 22, 2000   Volume 32, Issue 4 301-306 doi: 10.2746/042516400777032156
Peek SF, Divers TJ.The medical approach to treatment of cholangiohepatitis and cholelithiasis in 9 horses is described. Seven horses were treated successfully and returned to normal use, with a minimum follow-up period of 12 months. Long-term antimicrobial therapy was believed to be critical in those cases that survived, with a median treatment duration of 51 days (range 17-124 days). Treatment failure was associated with severe periportal and bridging hepatic fibrosis from biopsy material obtained at admission in 2 horses, one of whom also presented with hyperammonaemic hepatic encephalopathy. Transabdominal ul...
A review of medical treatment for peptic ulcer disease.
Equine veterinary journal. Supplement    March 4, 2000   Issue 29 45-49 doi: 10.1111/j.2042-3306.1999.tb05168.x
MacAllister CG.No abstract available
Superficial digital flexor tendonitis in thoroughbred race horses: outcome following non-surgical treatment and superior check desmotomy.
Australian veterinary journal    November 5, 1997   Volume 75, Issue 9 631-635 doi: 10.1111/j.1751-0813.1997.tb15356.x
Gibson KT, Burbidge HM, Pfeiffer DU.This study documents the results of non-surgical treatment and treatment by superior check desmotomy in Thoroughbred racehorses with superficial digital flexor (SDF) tendonitis. Methods: A prospective study was made of 124 thoroughbred racehorses with unilateral or bilateral SDF tendonitis. Methods: The flexor tendons were assessed by physical and ultrasonographic examination before treatment, and the lesions detected in affected tendons were characterised according to lesion type, length and cross-sectional area. Ninety three horses were managed non-surgically and 31 by superior check desmoto...
Medical management of right dorsal colitis in 5 horses: a retrospective study (1987-1993).
Journal of veterinary internal medicine    July 1, 1995   Volume 9, Issue 4 272-276 doi: 10.1111/j.1939-1676.1995.tb01079.x
Cohen ND, Carter GK, Mealey RH, Taylor TS.Right dorsal colitis in horses has been associated with administration of phenylbutazone. Although reports of right dorsal colitis in this species have described surgical treatment associated with a poor prognosis, we have had success treating this condition medically. This report describes 5 horses with right dorsal colitis confirmed during celiotomy that were initially managed medically. All horses had a history of intermittent abdominal pain; weight loss was noted in only 1 horse. The doses (2.0 to 4.6 mg/kg PO bid) and duration (5 to 30 days) of administration of phenylbutazone were not un...
Enterocutaneous fistulae in horses: 18 cases (1964 to 1992).
Veterinary surgery : VS    May 1, 1994   Volume 23, Issue 3 167-171 doi: 10.1111/j.1532-950x.1994.tb00465.x
Bristol DG.Enterocutaneous fistulae are rare in horses and occur most commonly as a complication of umbilical hernias or their treatment. Horses with enterocutaneous fistulae may be successfully treated by en bloc resection of the body wall and intestine or by allowing second intention healing. Complications associated with surgical intervention include fever, colic, incisional problems, and recurrence of the fistula. Nonsurgical management of two horses with presumptive large colon fistulae resulted in resolution of the fistulae without complications.
Medical treatment and costs of sports-related injuries in a total population.
International journal of sports medicine    February 1, 1990   Volume 11, Issue 1 66-72 doi: 10.1055/s-2007-1024765
de Loës M.A prospective study of acute injuries from sports and physical exercise was carried out during 1 year in a total population of a municipality with 31,620 inhabitants. The medical treatment and the services required for the injuries have been calculated and related to the total consumption of medical care in the municipality. A total of 571 injuries (17% of all injuries) occurred in 28 different sports: 65% of the injured were males. Sports injuries accounted for 3% of all acute visits and there were altogether 1,083 outpatient visits, which yields a mean of 1.9 visits per injury. Related to th...
Esophageal disorders in 61 horses. Results of nonsurgical and surgical management.
Veterinary surgery : VS    November 1, 1989   Volume 18, Issue 6 432-438 doi: 10.1111/j.1532-950x.1990.tb01120.x
Craig DR, Shivy DR, Pankowski RL, Erb HN.Obstructive esophageal disorders in 61 horses included feed or foreign body impaction (27 horses), strictures (18 horses), perforations (11 horses), and diverticula (5 horses). Horses with feed impaction were treated nonsurgically (25 horses) or by esophagotomy (2 horses). Survival to discharge was 78%, and 37% of these had persistent chronic obstruction at home. Long-term survival was 52%. Long-term survival of nine horses treated nonsurgically for esophageal strictures was 22%; for nine horses treated surgically it was 44%. Long-term survival of horses treated nonsurgically was significantly...
The reservoir function of the equine cecum and ventral large colon–its relation to chronic non-surgical obstructive disease with colic.
The Cornell veterinarian    July 1, 1982   Volume 72, Issue 3 233-241 
Sellers AF, Lowe JE, Rendano VT, Drost CJ.No abstract available
[Results of hippotherapeutic measures – attempt at documentation of therapeutic successes (author’s transl)].
Das Offentliche Gesundheitswesen    April 1, 1979   Volume 41, Issue 4 201-205 
Tarnow A.No abstract available
Seven years’ experience with antilymphoblast globulin for renal transplantation from cadaver donors.
Annals of surgery    September 1, 1976   Volume 184, Issue 3 352-368 doi: 10.1097/00000658-197609000-00013
Najarian JS, Simmons RL, Condie RM, Thompson EJ, Fryd DS, Howard RJ, Matas AJ, Sutherland DE, Ferguson RM, Schmidtke JR.Antibody of the IgGab type can be isolated from horses immunized with cultured human lymphoblasts plus complete Freund's adjuvant. The essential steps for the production of a safe, potent anti-human lymphoblast globulin (ALG) are: A) the use of early bleedings after immunization to reduce the titer of antibodies which react with red blood cells and platelets; B) careful absorption with human red blood cell stroma and platelets; C) stabilization with non-crystalline silica dioxide; D) chromatography through QAE sephadex to remove pyrogens, microaggregates and possible inhibitors of ALG activity...
A preliminary evaluation of Rn222 gamma radiation therapy in horses.
Australian veterinary journal    September 1, 1969   Volume 45, Issue 9 389-394 doi: 10.1111/j.1751-0813.1969.tb15103.x
Dixon RT.No abstract available