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Topic:Musculoskeletal System

The musculoskeletal system in horses encompasses the bones, muscles, tendons, ligaments, and joints that facilitate movement and provide structural support. This system is essential for locomotion, athletic performance, and overall health in equine species. The equine skeleton consists of approximately 205 bones, which are connected by joints and supported by a network of muscles and connective tissues. Tendons connect muscles to bones, while ligaments link bones to other bones, contributing to joint stability. The musculoskeletal system is subject to various conditions, including injuries, degenerative diseases, and developmental disorders, which can impact a horse's mobility and performance. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, physiology, pathology, and treatment of musculoskeletal conditions in horses.
Fractures sustained by racehorses in Japan during flat racing with special reference to track condition and racing time.
Veterinary journal (London, England : 1997)    November 4, 2005   Volume 170, Issue 3 369-374 doi: 10.1016/j.tvjl.2004.08.004
Oikawa M, Kusunose R.The purpose of this report is to describe the results of epidemiological surveys of racing-related fractures in Thoroughbred horses in Japan. In the period 1987-2000, a total of 10,203 fractures were diagnosed in 556,705 runners, resulting in an overall incidence of 1.83%. The annual incidence of fractures in flat racing during the 14-year period fluctuated between 1.44% and 2.19%. The majority of fractures affected the forelimbs. We found significant effects of track condition on injury incidence. The incidence of fractures decreased as track conditions on turf became softer and increased as ...
Role of endochondral ossification of articular cartilage and functional adaptation of the subchondral plate in the development of fatigue microcracking of joints.
Bone    November 4, 2005   Volume 38, Issue 3 342-349 doi: 10.1016/j.bone.2005.08.020
Muir P, McCarthy J, Radtke CL, Markel MD, Santschi EM, Scollay MC, Kalscheur VL.The mechanisms that regulate functional adaptation of the articular ends of long bones are poorly understood. However, endochondral ossification of articular cartilage and modeling/remodeling of the subchondral plate and epiphyseal trabeculae are important components of the adaptive response. We performed a histologic study of the distal end of the third metacarpal/metatarsal bone of Thoroughbreds after bones were bulk-stained in basic fuchsin and calcified sections were prepared. The Thoroughbred racehorse is a model of an extreme athlete which experiences particularly high cyclic strains in ...
Functional adaptation through changes in regional biochemical characteristics during maturation of equine superficial digital flexor tendons.
American journal of veterinary research    November 3, 2005   Volume 66, Issue 9 1623-1629 doi: 10.2460/ajvr.2005.66.1623
Lin YL, Brama PA, Kiers GH, DeGroot J, van Weeren PR.To quantify and compare biochemical characteristics of the extracellular matrix (ECM) of specimens harvested from tensional and compressive regions of the superficial digital flexor tendon (SDFT) of horses in age classes that include neonates to mature horses. Methods: Tendon specimens were collected on postmortem examination from 40 juvenile horses (0, 5, 12, and 36 months old) without macroscopically visible signs of tendonitis. Methods: Central core specimens of the SDFT were obtained with a 4-mm-diameter biopsy punch from 2 loaded sites, the central part of the mid-metacarpal region and th...
Determining effective centroid position in biomechanical testing: a technique for simplifying whole bone analysis.
Journal of biomechanical engineering    October 27, 2005   Volume 127, Issue 5 736-741 doi: 10.1115/1.1993663
Whan G, Runciman RJ, Hurtig M.Whole bone in vitro biomechanical compressive testing can be complicated by three factors: sample asymmetry, heterogeneous material properties, and unknown effective centroid location. Methods: The technique presented here facilitates the calculation of effective centroid position, modulus of elasticity and equivalent uniform strain magnitude for a cross section of bone from a simple whole bone compressive test. Simplification of section response to load is achieved through a combination of linear beam and simple planer geometry theory. The technique requires three longitudinal strain gauges b...
Toe-out conformation in thoroughbred horses in Sudan.
The Veterinary record    October 26, 2005   Volume 157, Issue 17 528 doi: 10.1136/vr.157.17.528
Hovell R, Symons D, Nahas A.No abstract available
Systematic ultrasonographic investigation of the equine tarsus.
Veterinary research communications    October 26, 2005   Volume 29 Suppl 2 309-313 doi: 10.1007/s11259-005-0069-2
Valentini S, Guereño JM, Spinella G, Fedrigo M.No abstract available
Radiographic diagnosis: foreign body in the distal interphalangeal joint. Giraldo L, Redding WR.No abstract available
Contractile effects of 5-hydroxytryptamine and 5-carboxamidotryptamine in the equine jejunum.
British journal of pharmacology    October 19, 2005   Volume 147, Issue 1 23-35 doi: 10.1038/sj.bjp.0706431
Delesalle C, Deprez P, Schuurkes JA, Lefebvre RA.The use of human prokinetic drugs in colic horses leads to inconsistent results. This might be related to differences in gastrointestinal receptor populations. The motor effects of 5-hydroxytryptamine (5-HT; serotonin) on the equine mid-jejunum were therefore studied. Longitudinal muscle preparations were set up for isotonic measurement. 5-HT induced tonic contractions with superimposed phasic activity; these responses were not influenced by tetrodotoxin and atropine, suggesting a non-neurogenic, non-cholinergic pathway. The 5-HT receptor antagonists GR 127935 (5-HT(1B,D)), ketanserin (5-HT(2A...
Evaluation of horseshoe characteristics and high-speed exercise history as possible risk factors for catastrophic musculoskeletal injury in thoroughbred racehorses.
American journal of veterinary research    September 22, 2005   Volume 66, Issue 8 1314-1320 doi: 10.2460/ajvr.2005.66.1314
Hernandez JA, Scollay MC, Hawkins DL, Corda JA, Krueger TM.To evaluate horseshoe characteristics and high-speed exercise history as risk factors for catastrophic musculoskeletal injury in Thoroughbred racehorses. Methods: 377 horses (37,529 race starts). Methods: Shoe characteristics included material, toe grab height, heel traction device, pads, and rim shoes. Racing variables were obtained from a computerized database. Forty-three horses that had a musculoskeletal injury and then failed to race or train for 6 months (cases) and 334 noninjured horses from the same race in which a horse was injured (controls) were compared regarding risk factors. Resu...
Use of synovial fluid and serum biomarkers in equine bone and joint disease: a review.
Equine veterinary journal    September 17, 2005   Volume 37, Issue 5 473-482 doi: 10.2746/042516405774480102
McIlwraith CW.No abstract available
Functional consequences of cartilage degeneration in the equine metacarpophalangeal joint: quantitative assessment of cartilage stiffness.
Equine veterinary journal    September 17, 2005   Volume 37, Issue 5 462-467 doi: 10.2746/042516405774480012
Brommer H, Laasanen MS, Brama PA, van Weeren PR, Helminen HJ, Jurvelin JS.No quantitative data currently exist on the relationship of the occurrence of cartilage degeneration and changes in site-specific biomechanical properties in the metacarpophalangeal (MCP) joint in the horse. Objective: To gain insight into the biomechanical consequences of cartilage deterioration at 2 differently loaded sites on the proximal articular surface of the proximal phalanx (P1). Objective: Static and dynamic stiffness of articular cartilage decreases significantly in degenerated cartilage. Methods: Cartilage degeneration index (CDI) values were measured at the lateral dorsal margin (...
Incomplete sagittal fracture of the talus in 11 racehorses: outcome.
Equine veterinary journal    September 17, 2005   Volume 37, Issue 5 457-461 doi: 10.2746/042516405774480030
Davidson EJ, Ross MW, Parente EJ.Little information exists regarding talus fractures in the horse and there have been no previously published case series of racehorses diagnosed with incomplete sagittal fracture of the talus. Objective: To describe the diagnosis, treatment and post injury performance of horses with incomplete sagittal fracture of the talus. Methods: Medical records of 11 racehorses (8 Standardbreds and 3 Thoroughbreds) admitted between January 1992 and January 1999 were reviewed. Subject details, anamnesis, results of lameness examination, radiographs and nuclear scintigraphic findings were evaluated. Racing ...
Training-related factors associated with dorsometacarpal disease in young Thoroughbred racehorses in the UK.
Equine veterinary journal    September 17, 2005   Volume 37, Issue 5 442-448 doi: 10.2746/042516405774480085
Verheyen KL, Henley WE, Price JS, Wood JL.Dorsometacarpal disease (DMD) is common in young Thoroughbred (TB) racehorses, often interfering with their training programme. No reports exist on incidence rate or associated risk factors in the UK. Objective: To estimate the incidence rate of DMD in TB horses in training for flat racing in the UK and identify associated risk factors, particularly in relation to training regimens. Methods: Data were drawn from a large prospective study in which TB horses in 13 training yards were monitored for a period of up to 2 years, recording daily training information and details of musculoskeletal inju...
A novel method for determination of collagen orientation in cartilage by Fourier transform infrared imaging spectroscopy (FT-IRIS).
Osteoarthritis and cartilage    September 9, 2005   Volume 13, Issue 12 1050-1058 doi: 10.1016/j.joca.2005.07.008
Bi X, Li G, Doty SB, Camacho NP.The orientation of collagen molecules is an important determinant of their functionality in connective tissues. The objective of the current study is to establish a method to determine the alignment of collagen molecules in histological sections of cartilage by polarized Fourier transform infrared imaging spectroscopy (FT-IRIS), a method based on molecular vibrations. Methods: Polarized FT-IRIS data obtained from highly oriented tendon collagen were utilized to calibrate the derived spectral parameters. The ratio of the integrated areas of the collagen amide I/II absorbances was used as an ind...
Mechanical and functional properties of the equine superficial digital flexor tendon.
Veterinary journal (London, England : 1997)    September 1, 2005   Volume 170, Issue 2 184-192 doi: 10.1016/j.tvjl.2004.03.021
Dowling BA, Dart AJ.The in vitro and in vivo mechanical properties of the superficial digital flexor tendon have been described. To date the focus has been on single load to failure testing, however refined in vivo methods may prove useful to evaluate the effects of treatment and exercise on tendons. During maximal exercise, the adult superficial digital flexor tendon operates close to its functional limits with a narrow biomechanical safety margin. This combined with exercise and age associated microdamage, and a limited adaptive ability may increase the risk of fatigue failure. Studies evaluating treatment regi...
What is your diagnosis? Medial sagittal patella fracture.
Journal of the American Veterinary Medical Association    August 27, 2005   Volume 227, Issue 3 381-382 doi: 10.2460/javma.2005.227.381
Janicek JC, Witte S.No abstract available
Harnessing the stem cell for the treatment of tendon injuries: heralding a new dawn?
British journal of sports medicine    August 25, 2005   Volume 39, Issue 9 582-584 doi: 10.1136/bjsm.2005.015834
Smith RK, Webbon PM.No abstract available
What is your diagnosis? Swelling of the soft tissue around the carpal joint. Osteomyelitis of the accessory carpal bone.
Journal of the American Veterinary Medical Association    August 25, 2005   Volume 227, Issue 4 551-552 doi: 10.2460/javma.2005.227.551
Witte S, Rodgerson DH.No abstract available
Effects of training on potassium homeostasis during exercise and skeletal muscle Na+,K(+)-ATPase concentration in young adult and middle-aged Dutch Warmblood horses.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1252-1258 doi: 10.2460/ajvr.2005.66.1252
Suwannachot P, Joosten BJ, Klarenbeek A, Hofma J, Enzerink E, van Weeren PR, Everts ME.To investigate the effects of moderate short-term training on K+ regulation in plasma and erythrocytes during exercise and on skeletal muscle Na+,K(+)-ATPase concentration in young adult and middle-aged horses. Methods: Four 4- to 6-year-old and four 10- to 16-year-old Dutch Warmblood horses. Methods: The horses underwent a 6-minute exercise trial before and after 12 days of training. Skeletal muscle Na+,K(+)-ATPase concentration was analyzed in gluteus medius and semitendinosus muscle specimens before and after the 12-day training period. Blood samples were collected before and immediately af...
Influence of age, site, and degenerative state on the speed of sound in equine articular cartilage.
American journal of veterinary research    August 23, 2005   Volume 66, Issue 7 1175-1180 doi: 10.2460/ajvr.2005.66.1175
Brommer H, Laasanen MS, Brama PA, van Weeren PR, Barneveld A, Helminen HJ, Jurvelin JS.To determine the speed of sound (SOS) in equine articular cartilage and investigate the influence of age, site in the joint, and cartilage degeneration on the SOS. Methods: Cartilage samples from 38 metacarpophalangeal joints of 38 horses (age range, 5 months to 22 years). Methods: Osteochondral plugs were collected from 2 articular sites of the proximal phalanx after the degenerative state was characterized by use of the cartilage degeneration index (CDI) technique. The SOS was calculated (ratio of needle-probe cartilage thickness to time of flight of the ultrasound pulse), and relationships ...
Extracellular matrix composition of the equine superficial digital flexor tendon: relationship with age and anatomical site.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    August 20, 2005   Volume 52, Issue 7 333-338 doi: 10.1111/j.1439-0442.2005.00742.x
Lin YL, Brama PA, Kiers GH, van Weeren PR, DeGroot J.The objectives of the present study were to test the hypotheses that: (1) the composition of the extracellular matrix of the equine superficial digital flexor tendon (SDFT) shows great functional similarities with articular cartilage, i.e. that significant differences exist in biochemical composition of differently loaded areas (which in the case of tendons may be more apparent as tendon shows more obvious differences than cartilage); and (2) that, as in articular cartilage, no substantial alterations in biochemical composition take place during ageing once adulthood has been attained. Tendon ...
Carpal collateral ligament desmopathy in three horses.
The Veterinary record    August 16, 2005   Volume 157, Issue 7 197-201 doi: 10.1136/vr.157.7.197
Desmaizières LM, Cauvin ER.The radiographic and ultrasonographic findings in three horses with severe damage to the collateral ligaments of the carpus, associated with degenerative joint disease, are described. The horses remained lame despite prolonged rest and medical management, primarily because of the progression of the joint disease. Ultrasonography was found to be an accurate method for diagnosing the injury to the ligaments and is recommended as part of a routine examination in suspected carpal injuries.
A non-invasive method of tendon force measurement.
Journal of biomechanics    August 9, 2005   Volume 38, Issue 10 2124-2129 doi: 10.1016/j.jbiomech.2004.09.012
Pourcelot P, Defontaine M, Ravary B, Lemâtre M, Crevier-Denoix N.The ability to measure the forces exerted in vivo on tendons and, consequently, the forces produced by muscles on tendons, offers a unique opportunity to investigate questions in disciplines as varied as physiology, biomechanics, orthopaedics and neuroscience. Until now, tendon loads could be assessed directly only by means of invasive sensors implanted within or attached to these collagenous structures. This study shows that the forces acting on tendons can be measured, in a non-invasive way, from the analysis of the propagation of an acoustic wave. Using the equine superficial digital flexor...
Design and demonstration of a dynamometric horseshoe for measuring ground reaction loads of horses during racing conditions.
Journal of biomechanics    August 9, 2005   Volume 38, Issue 10 2102-2112 doi: 10.1016/j.jbiomech.2004.08.024
Roland ES, Hull ML, Stover SM.Because musculoskeletal injuries to racehorses are common, instrumentation for the study of factors (e.g. track surface), which affect the ground reaction loads in horses during racing conditions, would be useful. The objectives of the work reported by this paper were to (1) design and construct a novel dynamometric horseshoe that is capable of measuring the complete ground reaction loading during racing conditions, (2) characterize static and dynamic measurement errors, and (3) demonstrate the usefulness of the instrument by collecting example data during the walk, trot, canter, and gallop fo...
Comminuted fracture of the distal sesamoid bone and distal rupture of the deep digital flexor tendon. Hoegaerts M, Pille F, De Clercq T, Fulton IC, Saunders JH.A 10-year-old show jumper was evaluated for an acute severe lameness (grade 4 of 5) of the right foreleg. During weight bearing, the toe of the affected limb rotated dorsally suggesting rupture of the deep digital flexor tendon (DDFT). Upon radiographic examination of the hoof, a severe erosion at the flexor surface and a parasagittal fracture of the distal sesamoid bone were found. Ultrasonographic examination confirmed rupture of the DDFT. These findings were confirmed on post-mortem examination. Prior to the acute lameness, the horse was treated with corticosteroid injections into the podot...
Orthopedic disorders in neonatal foals.
The Veterinary clinics of North America. Equine practice    July 30, 2005   Volume 21, Issue 2 357-vi doi: 10.1016/j.cveq.2005.04.008
Trumble TN.The first month of life is a vulnerable time for foals. They must adjust to their environment while they are still compromised immunologically, and their musculoskeletal system is rapidly growing and adjusting to stresses from an increasing amount of exercise. Therefore, if a foal is born with or acquires an abnormality or disease related to the musculoskeletal system, rapid adjustments must be made to allow the foal to grow and respond so that future athletic performance will not be compromised. Problems must be identified early, which requires thorough examinations. This article summarizes t...
Hereditary skeletal muscle diseases in the horse. A review.
The veterinary quarterly    July 19, 2005   Volume 27, Issue 2 65-75 doi: 10.1080/01652176.2005.9695187
Nollet H, Deprez P.Since riders nowadays are expecting the highest level of performance from their horses, muscular disorders therefore represent a major problem for the equine athlete. A lot of research has been done to identify muscular disorders and their etiopathogenesis. Both acquired and inherited forms of muscle diseases have been described. In this review only the latter forms will be mentioned. Major signs of all muscle disorders are muscular stiffness, cramping or pain, muscular fasciculations, muscular atrophy and exercise intolerance. Muscle biopsies can help to identify the cause of rhabdomyolysis o...
Common variable immunodeficiency in three horses with presumptive bacterial meningitis.
Journal of the American Veterinary Medical Association    July 15, 2005   Volume 227, Issue 1 114-87 doi: 10.2460/javma.2005.227.114
Pellegrini-Masini A, Bentz AI, Johns IC, Parsons CS, Beech J, Whitlock RH, Flaminio MJ.Three adult horses were evaluated for signs of musculoskeletal pain, dullness, ataxia, and seizures. A diagnosis of bacterial meningitis was made on the basis of results of CSF analysis. Because primary bacterial meningitis is so rare in adult horses without any history of generalized sepsis or trauma, immune function testing was pursued. Flow cytometric phenotyping of peripheral blood lymphocytes was performed, and proliferation of peripheral blood lymphocytes in response to concanavalin A, phytohemagglutinin, pokeweed mitogen, and lipopolysaccharide was determined. Serum IgA, IgM, and IgG co...
Risk factors for musculoskeletal injuries of the lower limbs in Thoroughbred racehorses in New Zealand.
New Zealand veterinary journal    July 14, 2005   Volume 53, Issue 3 171-183 doi: 10.1080/00480169.2005.36502
Perkins NR, Reid SW, Morris RS.To investigate risk factors for injury to musculoskeletal structures of the lower fore- and hind-limbs of Thoroughbred horses training and racing in New Zealand. Methods: A case-control study analysed by logistic regression was used to compare explanatory variables for musculoskeletal injuries (MSI) in racehorses. The first dataset, termed the Training dataset, involved 459 first-occurrence cases of lower-limb MSI in horses in training, and the second, the Starting dataset, comprised a subset of those horses that had started in at least one trial or race in the training preparation that ended ...
Risk factors for injury to the superficial digital flexor tendon and suspensory apparatus in Thoroughbred racehorses in New Zealand.
New Zealand veterinary journal    July 14, 2005   Volume 53, Issue 3 184-192 doi: 10.1080/00480169.2005.36503
Perkins NR, Reid SW, Morris RS.To investigate risk factors for injury to the superficial digital flexor tendon (SDFT) and suspensory apparatus (SA) of the forelimbs in Thoroughbred racehorses in New Zealand. Methods: Poisson and negative binomial regression, with exposure time represented by cumulative training days for each horse, were used to relate explanatory variables to the incidence rate (IR) of cases of inflammation of the SDFT (n=51), and injuries involving the SA (n=48) in a population of 1,571 commercially- trained racehorses over 554,745 study days. Only the first occurrence of an injury for any one horse was el...
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