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Topic:Pharmaceuticals
Pharmaceuticals in equine medicine encompass a wide range of drugs and therapeutic agents used to treat various conditions in horses. These substances include analgesics, anti-inflammatories, antibiotics, sedatives, and anthelmintics, among others. Each class of pharmaceuticals is designed to address specific health issues, such as pain management, infection control, or parasitic infestations. The pharmacokinetics and pharmacodynamics of these drugs can vary significantly between horses and other species, necessitating careful consideration of dosage and administration methods. This page compiles peer-reviewed research studies and scholarly articles that explore the development, efficacy, safety, and regulatory aspects of pharmaceuticals used in equine healthcare.
A note on a simple estimation of amphetamine, methylamphetamine and ephedrine in horse urine. A chromatographic separation of amphetamine, methylamphetamine and ephedrine from horse urine is possible on alkaline Silica Gel G plates developed with acetone-methanol (1:3). After elution, the bases are determined colorimetrically. The intensity of the violet colour resulting from the nitration of amphetamine is measured in a Unicam SP1300 colorimeter using filter No. 1 (sensitivity 50–250 μg). The colour produced by the interaction of methylamphetamine, sodium nitro-prusside, acetaldehyde and triethanolamine is measured at 590 mμ (sensitivity 200–2,000 μg). Ephedrine was determined ...
Tissue distribution of sulfadimethoxine and sulfamonomethoxine in horses after intravenous injection. The author has already reported on the time course of blood level of sulfonamides in horses at various dose schedules3). The present paper is concerned with the tissue distri-bution of sulfadimethoxine and sulfamonomethoxine in horses. The distribution of sulfonamides has been reported by KoNDol) in experimental animals, in which the concentrations of these drugs in the kidney, liver, lung and spleen were found to be close to the blood level. Many investigators ascribed the low concen-tration of sulfonamides in the spinal fluid to the existence of a blood-brain barrier, and also observed that ...
