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Topic:Prognosis

Prognosis in horses refers to the prediction of the likely outcome or course of a disease or injury in equine patients. It involves assessing various factors such as the nature and severity of the condition, the horse's overall health, and response to treatment. Prognostic evaluations help veterinarians and horse owners make informed decisions regarding treatment options, management strategies, and potential recovery. The process often incorporates clinical assessments, diagnostic tools, and historical data to estimate the chances of recovery or progression. This page compiles peer-reviewed research studies and scholarly articles that explore methodologies, factors influencing prognostic outcomes, and the implications of prognostic evaluations in equine veterinary practice.
Colic: the clinician’s approach to diagnosis, prognosis and therapy.
Equine veterinary journal    July 1, 1983   Volume 15, Issue 3 185 doi: 10.1111/j.2042-3306.1983.tb01756.x
No abstract available
Prognosis in equine colic: a comparative study of variables used to assess individual cases.
Equine veterinary journal    July 1, 1983   Volume 15, Issue 3 211-215 doi: 10.1111/j.2042-3306.1983.tb01768.x
Parry BW, Anderson GA, Gay CC.The present retrospective study compared objectively the prognostic value of many variables routinely used in the assessment of equine colic cases. The best prognostic variables were those which assessed the integrity of cardiovascular function. Ranked in order of decreasing merit the following variables were able to discriminate between horses which lived and those which died: systolic pressure, blood lactate concentration, oral mucous membrane capillary refill time, diastolic pressure, arterial pulse amplitude, degree of mental depression, blood urea concentration, haematocrit, heart rate, h...
Fractures of the central and third tarsal bones in horses.
Journal of the American Veterinary Medical Association    June 1, 1983   Volume 182, Issue 11 1234-1238 
Tulamo RM, Bramlage LR, Gabel AA.The case histories and follow-up data for 11 horses with slab fractures of the central or 3rd tarsal bones were examined for information pertaining to the diagnosis, which was difficult to identify, treatment, which was proven ineffective, and the prognosis, which was shown to be poor for return to racing. The purpose of the study was to define the results that could be obtained by nonoperative methods, in an attempt to determine whether surgical treatment was advisable. Nine of the horses were Standardbreds and 2 were Thoroughbreds; all horses were 2 to 4 years old and were being exercised at...
Prosthetic repair of large abdominal wall defects in horses and food animals.
Journal of the American Veterinary Medical Association    February 1, 1983   Volume 182, Issue 3 258-262 
Tulleners EP, Fretz PB.No abstract available
Cortisol (hydrocortisone) disappearance rate and pathophysiologic changes after bilateral adrenalectomy in equids.
American journal of veterinary research    February 1, 1983   Volume 44, Issue 2 276-279 
Slone DE, Ganjam VK, Purohit RC, Ravis WR.Six ponies and 1 horse were bilaterally adrenalectomized (BADX). The survival time of 2 of the 7 animals after BADX was 24 and 72 hours without supplemental corticosteroids. The cause of death was not related to the surgical technique. The biological half-life of cortisol (hydrocortisone) was estimated to be 2.1 +/- 0.6 hours. The disappearance of cortisol in the horse was found to be biphasic, composed of redistribution and elimination phases. Pathophysiologic changes (ie, increased serum sodium and chloride, increased PCV, and decreased serum potassium) similar to those seen in other species...
Review of 30 cases of peritonitis in the horse.
Equine veterinary journal    January 1, 1983   Volume 15, Issue 1 25-30 doi: 10.1111/j.2042-3306.1983.tb01693.x
Dyson S.Thirty cases of peritonitis, in which the diagnosis was based on a peritoneal fluid white blood cell count in excess of 10 x 10(9)/litre, are described. Colic, ileus, pyrexia, weight loss and diarrhoea were common presenting signs. Treatments included intravenous fluids, anti-inflammatory analgesics, broad spectrum antibiotics and anthelmintics. Duration of treatment was determined by the clinical condition of the horse and sequential analyses of the peritoneal fluid and the haemogram. In the majority of cases the primary cause of peritonitis was not accurately determined, but 21 horses (70 pe...
Joint mice in the fetlock joint–osteochondritis dissecans.
Nordisk veterinaermedicin    November 1, 1982   Volume 34, Issue 11 399-403 
Sønnichsen HV, Kristoffersen J, Falk-Rønne J.Joint mice in the horse is a wellknown condition, but during the last years diagnosed with increasing frequency. Ethiology and prognosis thus become of major interest. 53 cases of mice in the fetlock are examined and divided in 3 groups on the basis of localization and appearance. On one group characterised by a localization in the plantar aspect of the joint and clearly separated from the tuberosites of the first phalanx histological investigations were carried out resulting in the statement that the mice can be the result of osteochondrosis. Surgical intervention in cases with clinical sympt...
Atrial fibrillation in horses: factors associated with response to quinidine sulfate in 77 clinical cases.
The Cornell veterinarian    October 1, 1982   Volume 72, Issue 4 339-349 
Morris DD, Fregin GF.Seventy-seven horses with atrial fibrillation (AF) were treated orally with quinidine sulfate (QS) at the University of Pennsylvania, School of Veterinary Medicine, Thirty-seven horses (48%) had adverse reactions to QS, the most common of which were nasal mucosal edema, anorexia, colic, and diarrhea. The mean highest daily QS dose was slightly greater in horses showing toxicity (P less than 0.1) and their conversion rate was less (P less than 0.05). A schedule of gradually increasing QS dose was time consuming, costly and not associated with fewer adverse reactions. Horses were compared by the...
Prognostic value of endometrial biopsy in the mare: a retrospective analysis.
Journal of the American Veterinary Medical Association    October 1, 1982   Volume 181, Issue 7 680-681 
de la Concha-Bermejillo A, Kennedy PC.A retrospective analysis was made of 79 endometrial biopsy specimens obtained from mares with histories of infertility. The specimens were classified into 3 standard prognostic categories, according to the severity of the histologic changes. The 36 mares that had few endometrial lesions (category I) had a foaling rate of 78%. The 29 mares that had more severe endometrial changes (category II) had a foaling rate of 55%. The 14 mares with the most severe endometrial lesions (category III) had a foaling rate of 35%. The pregnancy losses for each category were 9.7%, 23.8%, and 44.4%, respectively....
[Diagnostical and prognostical value of blood lactate concentration and its level in peritoneal fluid in colic of the horse].
DTW. Deutsche tierarztliche Wochenschrift    July 6, 1982   Volume 89, Issue 7 295-299 
Genn HJ, Hertsch B.No abstract available
The anion gap as a prognostic indicator in horses with abdominal pain.
Journal of the American Veterinary Medical Association    July 1, 1982   Volume 181, Issue 1 63-65 
Bristol DG.The anion gap was calculated for each of 90 horses with signs of abdominal pain, using laboratory data obtained shortly after admission. The anion gap was defined as the difference between the sodium concentration (mEq/L) and the sum of the chloride and bicarbonate concentrations. To evaluate the use of the anion gap as a prognostic indicator, the survival rates were calculated for horses whose anion gap concentrations were within various ranges. It was found that the probability of survival decreased as the anion gap progressively increased about 20 mEq/L. The survival rates for increasing ra...
Medical management of congestive heart failure in a horse.
Journal of the American Veterinary Medical Association    April 15, 1982   Volume 180, Issue 8 878-883 
Brumbaugh GW, Thomas WP, Hodge TG.A 4-year-old Quarter Horse gelding with atrial fibrillation, mitral regurgitation, and signs of bilateral congestive heart failure was initially treated IV with digoxin and furosemide. After parenteral digitalization, a daily maintenance dose of digoxin was administered orally at a rate of 21.7 micrograms/kg of body weight. At this dosage, a steady-state serum digoxin concentration of 2.3 ng/ml was achieved without clinical signs of toxicosis. The furosemide dosage was decreased and eventually discontinued as clinical improvement occurred. Clinical signs of congestive heart failure were contro...
Pulmonary atresia with dextroposition of the aorta and ventricular septal defect in three Arabian foals.
Veterinary pathology    March 1, 1982   Volume 19, Issue 2 160-168 doi: 10.1177/030098588201900207
Vitums A, Bayly WM.Three Arabian males foals were presented with cyanosis, heart murmur, and exercise intolerance, Results of clinical evaluation suggested a tentative diagnosis of ventricular septal defect in conjunction with malformations of the great arteries. Each foal had a poor prognosis and was killed at the owners' requests. At necropsy, the malformed hearts of the three foals were virtually identical. Each heart had a large defect in the upper interventricular septum. The aorta originated from the hypertrophied right ventricle and partially overrode the ventricular septal defect. The aortic ostium was g...
Atrial fibrillation in horses: a review of 106 clinical cases, with consideration of prevalence, clinical signs, and prognosis.
Journal of the American Veterinary Medical Association    February 1, 1982   Volume 180, Issue 3 261-265 
Deem DA, Fregin GF.No abstract available
Pedal bone rotation as a prognostic sign in laminitis of horses.
Journal of the American Veterinary Medical Association    February 1, 1982   Volume 180, Issue 3 251-253 
Stick JA, Jann HW, Scott EA, Robinson NE.We reviewed 91 cases of laminitis in horses admitted to the Michigan State University Veterinary Clinical Center between Jan 1, 1973 and Dec. 30, 1978. From information in the case records and from the results of a telephone questionnaire, cases were classified into 4 categories on the basis of return to athletic function. The degree of pedal bone rotation was inversely correlated with return to athletic performance. Horses with less than 5.5 degrees rotation returned to former athletic function, whereas horses with more than 11.5 degrees rotation lost their use as performance animals. Ponies ...
Subchondral cystic and related lesions affecting the equine pedal bone and stifle.
Equine veterinary journal    January 1, 1982   Volume 14, Issue 1 47-54 doi: 10.1111/j.2042-3306.1982.tb02334.x
Verschooten F, De Moor A.Twenty-nine horses were examined over a period of 8 years and found to have cystic lesions in the stifle (14 cases) or pedal bone (15 cases). The lesions are described and illustrated with radiographs. In the stifle 12 lesions were found on the femoral condyles (11 medially and one laterally) and 10 were typical subchondral cysts. One lesion was observed in the tibia and 3 in the patella. Bone cysts wee found unilaterally in the pedal bone (14 in the forelimbs and one in the hindlimb). All but 2 of the horses with lesions in the stifle or pedal bone were lame. The only treatment was rest. For ...
Traumatic fractures of the equine hock: a report of 13 cases.
Equine veterinary journal    January 1, 1982   Volume 14, Issue 1 62-68 doi: 10.1111/j.2042-3306.1982.tb02338.x
Jakovljevic S, Gibbs C, Yeats JJ.The clinical features, radiographic findings, management and outcome in 13 cases of traumatic fracture of the hock joint are reported. The principal fracture sites were the distal tibial malleoli (5 cases), the fibular tarsal bone (4 cases), the tibial tarsal bone (3 cases) and the proximal end of metatarsal IV (one case). An additional small chip fracture of the central tarsal was noted in 2 cases. Three horses were destroyed immediately after diagnosis, 2 failed to recover following surgical intervention and one remained lame and was destroyed after 3 months' rest. Seven horses recovered com...
Stifle lameness in the horse: a survey of 86 referred cases.
Equine veterinary journal    January 1, 1982   Volume 14, Issue 1 31-39 doi: 10.1111/j.2042-3306.1982.tb02331.x
Jeffcott LB, Kold SE.The clinical and radiological characteristics of stifle lameness in 86 horses are described. The majority of these cases had been lame for some weeks before referral. The most frequent diagnoses made were osteochondrosis dissecans (13 per cent) and subchondral bone cyst (38 per cent). Both of these conditions were seen principally in Thoroughbreds at or before the onset of training. The other bone lesions encountered were osteoarthritis (3 per cent), fractures (4 per cent) and "epiphysitis" (1 per cent). The commonest soft tissue condition was an atypical or partial upward fixation of the pate...
A quantitative study of the histological morphology of the endometrium of normal and barren mares.
Canadian journal of comparative medicine : Revue canadienne de medecine comparee    January 1, 1982   Volume 46, Issue 1 17-20 
Leishman D, Miller RB, Doig PA.The density of uterine glands, height of surface epithelium, numbers of hemosiderin laden macrophages, inflammatory cells and layers of periglandular fibrosis were evaluated in uterine biopsies from 40 mares. These features were found to be highly variable in normal equine endometrium. Minor pathological changes appeared to be masked by this normal variability. Atrophy of uterine glands was recognized in mares which had been barren for more than three years. No significant differences were found between barren and normal mares in the height of epithelium, number of hemosiderin laden macrophage...
Paralaryngeal abscess with laryngeal hemiplegia and fistulation in a horse.
The Canadian veterinary journal = La revue veterinaire canadienne    December 1, 1981   Volume 22, Issue 12 389-392 
Barber SM.A three year old Thoroughbred filly was examined because of bilateral nasal discharge and external swelling of the left laryngeal area. Endoscopy revealed an enlarged left arytenoid cartilage, left laryngeal hemiplegia and drainage of purulent material into the lumen of the larynx. Radiographs showed a large fluid and gas filled cavity overlying the caudal larynx and cranial trachea. Surgical drainage and debridement of the abscess led to complete healing by secondary intention. Laryngeal ventriculectomy was performed as a treatment for left laryngeal hemiplegia, but a grave prognosis for resp...
Equine carpal surgery: A review of 89 cases and evaluation of return to function.
Journal of the American Veterinary Medical Association    October 1, 1981   Volume 179, Issue 7 682-685 
Lindsay WA, Horney FD.During a 6-year period, carpal arthrotomies were performed on 89 horses with carpal fractures. Fifty-two percent of the fractures involved the left forelimb; the 3rd carpal bone was most often involved (42%), followed by the radial carpal bone (30%). The effect of surgery on the performance of a subgroup of 48 thoroughbreds was evaluated by comparing the number of starts, level of racing (claiming value), and earnings for the 12 months of racing preceding and following arthrotomy. The data indicated that carpal arthrotomy in the Thoroughbred carries with it a favorable prognosis inasmuch as 80...
The use of endometrial biopsy in the infertile mare.
The Canadian veterinary journal = La revue veterinaire canadienne    March 1, 1981   Volume 22, Issue 3 72-76 
Doig PA, McKnight JD, Miller RB.The results of a study on endometrial biopsies obtained from 700 infertile mares are reported. Infiltrative endometritis was present in 51% consisting of a combination of an acute and chronic cellular response in 6%, mild chronic infiltrations in 35% and moderate to severe chronic infiltrations in 10%. Demonstrable endometrial fibrosis was found in 88% of the mares with the majority having mild (51%) or moderate (35%) changes. The age of the mares and the average number of years barren gradually increased with the severity of endometrial fibrosis, as did the combined incidence of fetal loss (e...
Data base for weight loss and chronic diarrhea–2.
Veterinary medicine, small animal clinician : VM, SAC    February 1, 1981   Volume 76, Issue 2 225-230 
Coffman J.No abstract available
Determination of plasma fibrinogen concentration in the horse.
American journal of veterinary research    January 1, 1981   Volume 42, Issue 1 100-104 
Campbell MD, Bellamy JE, Searcy GP.The microhematocrit heat-precipitation methods of Millar et al (1971) and Schalm et al (1975) were compared with the reference clottable protein method of Ratnoff and Menzie (1951) in the measurement of plasma fibrinogen concentration in horses. The millar et al method was more precise and accurate and showed better positive correlation with the reference method than did the Schalm et al method. There was no significant difference in the plasma fibrinogen concentration between healthy Thoroughbreds and healthy horses of other breeds. Horses with bacterial pneumonia and abscesses had significan...
Soft tissue masses in the fetlock joint of horses.
Australian veterinary journal    November 1, 1980   Volume 56, Issue 11 533-536 doi: 10.1111/j.1751-0813.1980.tb02582.x
van Veenendaal JC, Moffatt RE.Eight cases of sessile, intra-articular soft tissue masses originating from the cranio-dorsal attachment of the capsule of the fetlock joint of horses are presented. In 4 of these cases an osteochondral fracture of the first phalanx was also present. Clinically the condition closely resembled villonodular synovitis; however the microscopic changes did not correspond to those reported. The clinical signs included lameness after exercise, joint effusion and pain on manipulation. The offending masses were surgically resected and their histology indicated a chronic proliferative synovitis. The res...
Volvulus of the large colon in the horse.
Journal of the American Veterinary Medical Association    October 1, 1980   Volume 177, Issue 7 629-630 
Barclay WP, Foerner JJ, Phillips TN.Volvulus of the large colon was diagnosed at surgery in 25 horses during a 4-year period. Two horses had a recurrence of the condition after successful correction. Mucosal necrosis was found to be a grave prognostic sign, as it was a consistent finding in horses that died at the time of surgery. Long-term colon dysfunction was not clinically evident in surviving horses.
Cytologic interpretation of peritoneal fluid in the evaluation of equine abdominal crises.
The Cornell veterinarian    July 1, 1980   Volume 70, Issue 3 232-246 
Adams SB, Fessler JF, Rebar AH.Cytologic examination of serial peritoneal fluid samples of nine experimental ponies was performed during a 72 hour period following laparotomy. Six of the ponies had jejunal infarction induced by occlusion of the corresponding vasculature. Cytologic examination was also performed on the peritoneal fluid of a series of horses with naturally occurring abdominal crises presented to the Large Animal Clinic. A rapid staining technique allowed evaluation of smears within 5 minutes of obtaining the fluid. Alterations in peritoneal fluid of the experimental and clinical cases reflected an acute infla...
Haematology as an aid to prognosis of chronic laminitis.
Equine veterinary journal    January 1, 1980   Volume 12, Issue 1 30-31 doi: 10.1111/j.2042-3306.1980.tb02297.x
Coffman JR, Hammond LS, Garner HE, Thawley DG, Selby LA.A COMMON progression of chronic laminitis is ischaemic necrosis with secondary infection a frequent complication. For 6 years we have performed a complete blood count (CBC) on all hospitalised horses (at the University of Missouri Veterinary Hospital) every Monday, Wednesday and Friday. Preliminary scrutiny of the results indicated that persistent elevation of the total white blood cell count (WBC) and neutrophilia was consistent with poor prognosis in horses affected with laminitis. Because of these considerations we decided to perform a retrospective examination of the blood cell d...
Treatment and prognosis for cunean tendon bursitis-tarsitis of Standardbred horses.
Journal of the American Veterinary Medical Association    November 15, 1979   Volume 175, Issue 10 1086-1088 
Gabel AA.During 1975 and 1976, 70 Standardbred horses with cunean bursitis-tarsitis were treated by cunean tenectomy or by more conservative approaches (rested, given corticosteroid injections in the cunean bursa and distal hock articulations, given an oral course of phenylbutazone, a combination of these) or were sold. In 1975, owners were urged to have cunean tenectomy done to horses that appeared to have potential to race well, and in 1976, the more conservative methods of management and treatment were recommended. Statistical analysis of racing performance data led to the conclusion that there was ...
Colic in the horse. A clinical and clinical chemical study of 42 cases.
Nordisk veterinaermedicin    October 1, 1979   Volume 31, Issue 10 1-32 
Svendsen CK, Hjortkjaer RK, Hesselholt M.42 horses were examined. The physical signs with relation to circulatory insufficiency and the abdominal disease were registered following a two-phased examination procedure. Great prognostic value was found in the degree of circulatory insufficiency judged by pulse rate and character, filling of the jugular vein, skin temperature, colour of mucous membranes, capillary refill time, sweating, depression, skin turgor and degree of enophthalmus. In making a causal diagnosis the abdomen was examined for shape, tenderness, peristaltic sounds, gastric dilation by siphoning, abnormal rectal findings ...