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Topic:Risk Factors

Risk factors in horses refer to variables or conditions that increase the likelihood of disease, injury, or other adverse health outcomes in equine populations. These factors can be intrinsic, such as age, breed, and genetic predisposition, or extrinsic, including environmental conditions, management practices, and exposure to infectious agents. Understanding risk factors is important for developing preventive strategies and improving health management in horses. This page aggregates peer-reviewed research studies and scholarly articles that explore the identification, assessment, and mitigation of risk factors in equine health, with the aim of enhancing disease prevention and promoting overall well-being in horses.
A study of leptospirosis in South African horses and associated risk factors.
Preventive veterinary medicine    September 24, 2016   Volume 134 6-15 doi: 10.1016/j.prevetmed.2016.09.019
Simbizi V, Saulez MN, Potts A, Lötter C, Gummow B.Most leptospiral infections in horses are asymptomatic; however, acute disease manifestations as well as reproductive failure and recurrent uveitis have been reported. In South Africa, the epidemiology of the disease in horses is not well documented. A serosurvey to determine what serovars were present in horses from Gauteng, KwaZulu-Natal and Western Cape Provinces and to get an estimate of the seroprevalence of leptospirosis was carried out from January 2013 until April 2014 with the assistance of four large equine hospitals located in these provinces. Furthermore, associations between poten...
Comparative Risk Analysis of Two Culicoides-Borne Diseases in Horses: Equine Encephalosis More Likely to Enter France than African Horse Sickness.
Transboundary and emerging diseases    September 23, 2016   Volume 64, Issue 6 1825-1836 doi: 10.1111/tbed.12577
Faverjon C, Leblond A, Lecollinet S, Bødker R, de Koeijer AA, Fischer EAJ.African horse sickness (AHS) and equine encephalosis (EE) are Culicoides-borne viral diseases that could have the potential to spread across Europe if introduced, thus being potential threats for the European equine industry. Both share similar epidemiology, transmission patterns and geographical distribution. Using stochastic spatiotemporal models of virus entry, we assessed and compared the probabilities of both viruses entering France via two pathways: importation of live-infected animals or importation of infected vectors. Analyses were performed for three consecutive years (2010-2012). Se...
Are horse age and incision length associated with surgical site infection following equine colic surgery?
Veterinary journal (London, England : 1997)    September 22, 2016   Volume 217 3-7 doi: 10.1016/j.tvjl.2016.09.004
Darnaud SJ, Southwood LL, Aceto HW, Stefanovski D, Tomassone L, Zarucco L.It is our clinical impression that age and incision length are more strongly associated with surgical site infection (SSI) following colic surgery than skin closure or wound protection method. Therefore, the objective of this observational clinical cohort study was to identify the risks for SSI in horses undergoing colic surgery. Data collection included pre-, intra-, and postoperative variables. Variables with P < 0.2 following univariable analysis were used in a logistic regression multivariable model. Variables with P <0.05 were included in the final model. Odds ratios (OR; 95% confid...
Prospective cohort study evaluating risk factors for the development of pasture-associated laminitis in the United Kingdom.
Equine veterinary journal    August 25, 2016   Volume 49, Issue 3 300-306 doi: 10.1111/evj.12606
Menzies-Gow NJ, Harris PA, Elliott J.Certain individuals appear to be predisposed to recurrent pasture-associated laminitis. Previous studies have predominantly investigated risk factors only after disease occurrence. Objective: To investigate risk factors for pasture-associated laminitis prior to disease occurrence. Methods: Prospective cohort study. Methods: Non-laminitic ponies aged ≥7 years were recruited. Body condition score (BCS), height, weight, crest height and thickness were measured and an overnight dexamethasone suppression test performed. Plasma or serum adiponectin, leptin, triglyceride, basal insulin, insulin pos...
An epidemiological survey on the prevalence of equine peripheral dental caries in the United Kingdom and possible risk factors for its development.
Equine veterinary journal    August 21, 2016   Volume 49, Issue 4 480-485 doi: 10.1111/evj.12610
Borkent D, Reardon RJM, McLachlan G, Smith S, Dixon PM.Equine peripheral caries (PC) is an increasingly recognised disorder that causes premature wear of teeth and dental fractures and thus has major welfare implications. Little information is available on its prevalence or severity in UK horses and there are no proven associations with any risk factors. Objective: To document the prevalence of PC over a wide area of the UK, assess its intraoral distribution and severity in affected horses and examine for potential risk factors for its development. Methods: Cross sectional study. Methods: Experienced personnel were recruited for a UK wide dental s...
Estimating the economic impact of a possible equine and human epidemic of West Nile virus infection in Belgium.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin    August 16, 2016   Volume 21, Issue 31 doi: 10.2807/1560-7917.ES.2016.21.31.30309
Humblet MF, Vandeputte S, Fecher-Bourgeois F, Léonard P, Gosset C, Balenghien T, Durand B, Saegerman C.This study aimed at estimating, in a prospective scenario, the potential economic impact of a possible epidemic of WNV infection in Belgium, based on 2012 values for the equine and human health sectors, in order to increase preparedness and help decision-makers. Modelling of risk areas, based on the habitat suitable for Culex pipiens, the main vector of the virus, allowed us to determine equine and human populations at risk. Characteristics of the different clinical forms of the disease based on past epidemics in Europe allowed morbidity among horses and humans to be estimated. The main costs ...
Notes from the Field: Fatal Infection Associated with Equine Exposure – King County, Washington, 2016.
MMWR. Morbidity and mortality weekly report    August 5, 2016   Volume 65, Issue 30 788 doi: 10.15585/mmwr.mm6530a5
Kawakami V, Rietberg K, Lipton B, Eckmann K, Watkins M, Oltean H, Kay M, Rothschild C, Kobayashi M, Van Beneden C, Duchin J.On March 17, 2016, Public Health-Seattle & King County in Washington was notified of two persons who received a diagnosis of Streptococcus equi subspecies zooepidemicus (S. zooepidemicus) infections. S. zooepidemicus is a zoonotic pathogen that rarely causes human illness and is usually associated with consuming unpasteurized dairy products or with direct horse contact (1). In horses, S. zooepidemicus is a commensal bacterium that can cause respiratory, wound, and uterine infections (2). The health department investigated to determine the magnitude of the outbreak, identify risk factors, and o...
Risk Factors for Equine Gastric Glandular Disease: A Case-Control Study in a Finnish Referral Hospital Population.
Journal of veterinary internal medicine    July 28, 2016   Volume 30, Issue 4 1270-1275 doi: 10.1111/jvim.14370
Mönki J, Hewetson M, Virtala AM.Equine gastric glandular disease (EGGD) is a term used to classify erosive and ulcerative diseases of the glandular mucosa of the equine stomach. Epidemiologic studies of risk factors for EGGD have not been reported. Objective: To determine risk factors for EGGD. Methods: Cases (n = 83) had endoscopic evidence of EGGD; controls (n = 34) included healthy horses and horses with equine squamous gastric disease (ESGD) without EGGD. Methods: Retrospective case-control study. The data were analyzed by multivariable logistic regression modeling. Analysis was performed on the full dataset. An addi...
Horses seropositive for Toxoplasma gondii, Sarcocystis spp. and Neospora spp.: Possible risk factors for infection in Brazil.
Microbial pathogenesis    July 27, 2016   Volume 99 30-35 doi: 10.1016/j.micpath.2016.07.016
Cazarotto CJ, Balzan A, Grosskopf RK, Boito JP, Portella LP, Vogel FF, Fávero JF, de C Cucco D, Biazus AH, Machado G, Da Silva AS.Many parasitic diseases are considered asymptomatic, even though some studies have shown that they may cause pathological changes in the host. Therefore, the aim of this study was to evaluate the occurrence of antibodies against Toxoplasma gondii, Neospora spp. and Sarcocystis spp. in horses, and to identify the risk factors for disease. For this, 174 horses were studied, 90 males and 84 females aged between two and 20 years old. Blood samples were collected and stored in tubes without anticoagulant to obtain serum, which was subjected to serological tests for T. gondii, Sarcocystis spp., and...
Has intravenous lidocaine improved the outcome in horses following surgical management of small intestinal lesions in a UK hospital population?
BMC veterinary research    July 27, 2016   Volume 12, Issue 1 157 doi: 10.1186/s12917-016-0784-7
Salem SE, Proudman CJ, Archer DC.Perioperative lidocaine treatment is commonly used in horses that undergo surgical treatment of colic, to prevent or treat postoperative ileus and reduce the effects of intestinal ischaemia-reperfusion injury. However, its clinical efficacy has not been evaluated in a large population of horses undergoing small intestinal surgery. The aim of the current study was to evaluate whether systemic lidocaine administration reduced the prevalence, volume and duration of postoperative reflux and improved rates of survival following surgical treatment of small intestinal lesions. Data were collected as ...
Treatment of sarcoids in equids: 230 cases (2008-2013).
Journal of the American Veterinary Medical Association    July 22, 2016   Volume 249, Issue 3 311-318 doi: 10.2460/javma.249.3.311
Haspeslagh M, Vlaminck LE, Martens AM.OBJECTIVE To evaluate outcomes following treatment of sarcoids in equids and to identify risk factors for treatment failure in these patients. DESIGN Retrospective case series. ANIMALS 230 equids with 614 sarcoids. PROCEDURES Records were searched to identify equids treated for ≥ 1 sarcoid between 2008 and 2013. A standardized protocol was used to determine treatment choice (electrosurgery, electrosurgery with intralesional placement of cisplatin-containing beads, topical administration of imiquimod or acyclovir, cryosurgery, bacillus Calmette-Guerin vaccine injection, or intralesional injec...
Quantitative analysis of the probability of introducing equine encephalosis virus (EEV) into The Netherlands.
Preventive veterinary medicine    July 7, 2016   Volume 131 48-59 doi: 10.1016/j.prevetmed.2016.07.005
Fischer EAJ, Martínez López EP, De Vos CJ, Faverjon C.Equine encephalosis is a midge-borne viral disease of equines caused by equine encephalosis virus (EEV, Orbivirus, Reoviridae), and closely related to African horse sickness virus (AHSV). EEV and AHSV share common vectors and show similar transmission patterns. Until now EEV has caused outbreaks in Africa and Israel. This study aimed to provide insight in the probability of an EEV outbreak in The Netherlands caused by infected vectors or hosts, the contribution of potential source areas (risk regions) to this probability, and the effectiveness of preventive measures (sanitary regimes). A stoch...
Twenty years of Hendra virus: laboratory submission trends and risk factors for infection in horses.
Epidemiology and infection    June 30, 2016   Volume 144, Issue 15 3176-3183 doi: 10.1017/S0950268816001400
Smith CS, McLAUGHLIN A, Field HE, Edson D, Mayer D, Ossedryver S, Barrett J, Waltisbuhl D.Hendra virus (HeV) was first described in 1994 in an outbreak of acute and highly lethal disease in horses and humans in Australia. Equine cases continue to be diagnosed periodically, yet the predisposing factors for infection remain unclear. We undertook an analysis of equine submissions tested for HeV by the Queensland government veterinary reference laboratory over a 20-year period to identify and investigate any patterns. We found a marked increase in testing from July 2008, primarily reflecting a broadening of the HeV clinical case definition. Peaks in submissions for testing, and visitat...
[Occurrance of antibodies against Leptospira in horses in Middle Germany].
Berliner und Munchener tierarztliche Wochenschrift    June 28, 2016   Volume 129, Issue 5-6 202-208 
Pikalo J, Sattler T, Eichinger M, Loitsch A, Sun H, Schmoll F, Schusser GF.Aim of the study was to detect antibodies and potential risk factors for an infec- tion with Leptospira in horses in Middle Germany. Serum samples of 314 horses were examined retrospectively by microscopic agglutination test for the presence of antibodies against eight Leptospira serovars. In total, 17.2% (n = 54) of the horses were positive for one or more of the serovars analyzed. The most prevalent serovar was lcterohaemorrhagiae (11.1%), followed by serovar Bratislava (9.6 %) and Grippotyphosa (1.9%). Mares showed a significantly higher occurrence of antibodies (p < 0.05) than geldings ...
Descriptive epidemiology of veterinary events in flat racing Thoroughbreds in Great Britain (2000 to 2013).
Equine veterinary journal    June 22, 2016   Volume 49, Issue 3 275-281 doi: 10.1111/evj.12592
Rosanowski SM, Chang YM, Stirk AJ, Verheyen KL.To date, no large scale studies have reported race-day events requiring veterinary attention in British Thoroughbreds racing on the flat. Quantifying and describing common injuries and health conditions affecting racehorses will enable targeted risk factor analysis aimed at reducing their occurrence. Objective: To describe the type and incidence of race-day veterinary events experienced by Thoroughbred racehorses participating in flat racing in the UK. Methods: Retrospective cohort study (2000 to 2013). Methods: Veterinary events recorded by race-day veterinarians were retrieved and linked to ...
Injury risks for on-road farm equipment and horse and buggy crashes in Pennsylvania: 2010-2013.
Traffic injury prevention    June 21, 2016   Volume 18, Issue 3 286-292 doi: 10.1080/15389588.2016.1198009
Gorucu S, Murphy DJ, Kassab C.The purpose of this study was to investigate characteristics associated with farm equipment and horse and buggy roadway crashes in relation to person, incident, and injury characteristics to identify appropriate points for injury incident prevention. Information on crashes occurring on public roads during the years 2010-2013 was obtained from the Pennsylvania Department of Transportation (PennDOT) and analyzed. There were 344 farm equipment and 246 horse and buggy crashes during the 4-year study period. These crashes involved 666 and 504 vehicles and 780 and 838 people, respectively. In incide...
Immune Dysfunction in Aged Horses.
The Veterinary clinics of North America. Equine practice    June 18, 2016   Volume 32, Issue 2 333-341 doi: 10.1016/j.cveq.2016.04.009
McFarlane D.The aging process in people is associated with changes in adaptive and innate immune responses. Similar changes occur in aged horses. Age-related progressive impairment in the ability to respond to pathogen challenge and an increased inflammatory reactivity may predispose geriatric horses to many diseases of old age. Specific recommendations for immune modification of older horses, including an age-appropriate vaccination schedule, are not currently available. In addition, the effect of old age on risk of infectious disease is poorly documented. More work is needed to better understand the int...
Interval prevalence of and factors associated with colic in horses hospitalized for ocular or orthopedic disease.
Journal of the American Veterinary Medical Association    June 17, 2016   Volume 249, Issue 1 90-95 doi: 10.2460/javma.249.1.90
Scherrer NM, Lassaline M, Richardson DW, Stefanovski D.OBJECTIVE To determine interval (1-year) prevalence of and factors associated with colic in horses hospitalized for ocular or orthopedic disease. DESIGN Cross-sectional study. ANIMALS 105 horses with ocular disease and 197 horses with orthopedic disease admitted to a veterinary teaching hospital between July 1, 2011, and June 30, 2012. PROCEDURES Medical records were reviewed to determine whether colic (abnormal behavior prompting abdominal palpation per rectum or nasogastric intubation) was observed during hospitalization. Data were collected on putative risk factors for colic, including reas...
Prevalence and risk factors of Theileria equi infection in horses in Minas Gerais, Brazil.
Veterinary parasitology, regional studies and reports    June 11, 2016   Volume 3-4 18-22 doi: 10.1016/j.vprsr.2016.05.005
Guimarães AM, Bruhn FRP, Ribeiro MJM, Rosa MHF, de Mello Garcia A, da Rocha CMBM, de Assis Rocha I.Theileria equi, a protozoon in the phylum Apicomplexa, is the causative agent of equine theileriosis. The aim of this cross-sectional study was to determine the prevalence of IgG antibodies against T. equi, by using the indirect fluorescent antibody test (IFAT) reaction and correlating the serostatus with some epidemiological variables relating to the way in which Mangalarga Marchador horses are raised in southern Minas Gerais, Brazil. In this study, 506 horses were used, all clinically healthy, on 53 horse farms distributed across 27 municipalities in southern Minas Gerais. The statistical te...
Analysis of Failure to Finish a Race in a Cohort of Thoroughbred Racehorses in New Zealand.
Animals : an open access journal from MDPI    May 25, 2016   Volume 6, Issue 6 doi: 10.3390/ani6060036
Tanner J, Rogers C, Bolwell C, Cogger N, Gee E, Mcllwraith W.The objective was to describe the incidence of failure to finish a race in flat-racing Thoroughbreds in New Zealand as these are summary indicators of falls, injuries and poor performance. Retrospective data on six complete flat racing seasons (n = 188,615 race starts) of all Thoroughbred flat race starts from 1 August 2005 to 31 July 2011 were obtained. The incidence of failure to finish events and binomial exact 95% confidence intervals were calculated per 1000 horse starts. The association between horse-, rider- and race-level variables with the outcomes failure to finish, pulled-up/fell an...
Equine herpesvirus – a constant threat.
The Veterinary record    May 15, 2016   Volume 178, Issue 20 499-500 doi: 10.1136/vr.i2318
Strang C.Camilla Strang of the Animal Health Trust provides an overview of the diagnosis and control of conditions associated with infection by equine herpesvirus.
Preventing and Investigating Horse-Related Human Injury and Fatality in Work and Non-Work Equestrian Environments: A Consideration of the Workplace Health and Safety Framework.
Animals : an open access journal from MDPI    May 6, 2016   Volume 6, Issue 5 33 doi: 10.3390/ani6050033
Chapman M, Thompson K.It has been suggested that one in five riders will be injured due to a fall from a horse, resulting in severe head or torso injuries. Attempts to reduce injury have primarily focussed on low level risk controls, such as helmets. In comparison, risk mitigation in high risk workplaces and sports is directed at more effective and preventative controls like training, consultation, safe work procedures, fit for purpose equipment and regular Workplace Health and Safety (WHS) monitoring. However, there has been no systematic consideration of the risk-reduction benefits of applying a WHS framework to ...
Can we use subchondral bone thickness on high-field magnetic resonance images to identify Thoroughbred racehorses at risk of catastrophic lateral condylar fracture?
Equine veterinary journal    May 6, 2016   Volume 49, Issue 2 167-171 doi: 10.1111/evj.12574
Tranquille CA, Murray RC, Parkin TD.Fractures of the lateral condyle of the third metacarpus (MC3) are a significant welfare concern in horseracing worldwide. Objective: The primary aim of this work was to identify magnetic resonance (MR) image-detectable prefracture markers that have the potential for use as a screening tool to identify horses at significant risk of catastrophic fracture. Methods: Case-control study of bone-level risk factors for fracture in racehorses. Methods: A total of 191 MC3s from horses, with and without lateral condylar fracture of MC3, were subjected to MR imaging. The depth of dense subchondral/trabec...
Colic in a working horse population in Egypt: Prevalence and risk factors.
Equine veterinary journal    May 2, 2016   Volume 49, Issue 2 201-206 doi: 10.1111/evj.12573
Salem SE, Scantlebury CE, Ezzat E, Abdelaal AM, Archer DC.Colic is an important health problem in managed horse populations. Currently, there is limited information about colic prevalence and risk factors for colic in working horse populations. Objective: To determine the prevalence of, and risk factors for, colic in a working horse population in Egypt and to describe management practices in this working horse population. Methods: Cross-sectional survey. Methods: Owners of 350 working horses were interviewed. Data about their horses, management and colic episodes in the preceding 12 months were collected. Dental examination was conducted on 342 horse...
Molecular detection and prevalence of Theileria equi and Babesia caballi in horses of central Balkan.
Acta parasitologica    April 15, 2016   Volume 61, Issue 2 337-342 doi: 10.1515/ap-2016-0044
Davitkov D, Vucicevic M, Stevanovic J, Krstic V, Slijepcevic D, Glavinic U, Stanimirovic Z.Equine piroplasmosis is significant tick-borne disease with wide distribution. The prevalence of equine piroplasmosis in Serbia, Montenegro and Bosnia and Herzegovina is unknown. In aim to obtain a first insight into the prevalence we performed molecular epidemiological study which included 142 horses, on seven locations in these three countries. We first performed PCR for the detection of a 450bp long section of the 18S rRNA of piroplasma-specific region. For all positive samples we have done multiplex PCR for the species detection. Species determination was further confirmed by sequencing PC...
Peri-anaesthetic complications in an equine referral hospital: Risk factors for post anaesthetic colic.
Equine veterinary journal    April 12, 2016   Volume 48, Issue 3 394 doi: 10.1111/evj.12567
Hughes KJ.No abstract available
New insights in professional horse racing; “in-race” heart rate data, elevated fracture risk, hydration, nutritional and lifestyle analysis of elite professional jockeys.
Journal of sports sciences    April 12, 2016   Volume 35, Issue 5 441-448 doi: 10.1080/02640414.2016.1171890
O'Reilly J, Cheng HL, Poon ET.Weight-making practices have been shown to impair musculoskeletal and physiological function of jockeys. This study investigated the "in-race" heart rate (HR) responses and hydration status during competitive racing, as well as selected physiological and lifestyle parameters of professional jockeys based in Hong Kong. "In-race" HR responses and early morning hydration status of 20 male jockeys were examined in hot and moderate climactic occasions. Additionally, bone mineral density (BMD), dietary intake and lifestyle choices were assessed. Osteopenia was observed in the calcanei of jockeys (le...
Polarisation of equine pregnancy outcome associated with a maternal MHC class I allele: Preliminary evidence.
Veterinary microbiology    April 6, 2016   Volume 188 34-40 doi: 10.1016/j.vetmic.2016.04.004
Kydd JH, Case R, Winton C, MacRae S, Sharp E, Ricketts SL, Rash N, Newton JR.Identification of risk factors which are associated with severe clinical signs can assist in the management of disease outbreaks and indicate future research areas. Pregnancy loss during late gestation in the mare compromises welfare, reduces fecundity and has financial implications for horse owners. This retrospective study focussed on the identification of risk factors associated with pregnancy loss among 46 Thoroughbred mares on a single British stud farm, with some but not all losses involving equid herpesvirus-1 (EHV-1) infection. In a sub-group of 30 mares, association between pregnancy ...
Prevalence, risk factors and genetic parameters of cresty neck in Pura Raza Español horses.
Equine veterinary journal    March 19, 2016   Volume 49, Issue 2 196-200 doi: 10.1111/evj.12569
Sánchez MJ, Azor PJ, Molina A, Parkin T, Rivero JL, Valera M.Cresty neck is a relatively common morphological defect in Pura Raza Español horses and other Baroque type horse breeds, which adversely affects the breeding industry. Objective: To establish the within-breed prevalence, possible associated factors and heritability of cresty neck in Pura Raza Español horses. Methods: Cross-sectional analysis of a large worldwide database of Pura Raza Español horses. Methods: The database included evaluations of 10,929 Pura Raza Español horses from 24 countries. Cresty neck score, on a 9 point scale, girth-to-height ratio, height at the withers, length of n...
Quantitative Risk Assessment for African Horse Sickness in Live Horses Exported from South Africa.
PloS one    March 17, 2016   Volume 11, Issue 3 e0151757 doi: 10.1371/journal.pone.0151757
Sergeant ES, Grewar JD, Weyer CT, Guthrie AJ.African horse sickness (AHS) is a severe, often fatal, arbovirus infection of horses, transmitted by Culicoides spp. midges. AHS occurs in most of sub-Saharan Africa and is a significant impediment to export of live horses from infected countries, such as South Africa. A stochastic risk model was developed to estimate the probability of exporting an undetected AHS-infected horse through a vector protected pre-export quarantine facility, in accordance with OIE recommendations for trade from an infected country. The model also allows for additional risk management measures, including multiple PC...
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