Veterinary care in horses encompasses the medical and preventive measures taken to maintain and improve the health and well-being of equine patients. It includes a wide range of practices such as routine health examinations, vaccinations, dental care, parasite control, and management of injuries and diseases. Veterinary care also involves diagnostic procedures, surgical interventions, and therapeutic treatments tailored to the specific needs of horses. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of equine veterinary care, including advancements in diagnostic techniques, treatment protocols, and health management strategies to support the well-being and performance of horses.
King CM, Evans DL, Rose RJ.Various cardiorespiratory and metabolic indices were assessed during treadmill exercise in Thoroughbred and Standardbred racehorses with T wave changes in 4 or more leads on the electrocardiogram or second-degree atrio-ventricular (AV) block, and in horses that had no abnormalities on clinical examination, resting electrocardiography or upper respiratory tract endoscopy. No significant differences in heart rate, plasma lactate concentration, arterial blood gases, oxygen uptake, run time, peak velocity, or blood and red cell volumes were found between normal horses and horses with T wave change...
Miles CA, Wardale RJ, Birch HL, Bailey AJ.Differential scanning calorimetry (DSC) of equine superficial digital flexor tendons revealed the presence of a small exothermic peak at 23 degrees C of unknown origin, and a large endothermic peak at 70 degrees C due to denaturation of cross-linked collagen fibres. In the central degenerated core of damaged tendons the denaturation temperature remained at 70 degrees C but the enthalpy decreased in relation to the extent of degeneration of the tendon. We suggest that this reduction in enthalpy is due to depolymerisation and denaturation of the collagen fibres. This contention is supported by t...
Schneider RK, Ragle CA, Carter BG, Davis WE.Osteochondral fragments detected in the proximal interphalangeal joint in the pelvic limbs of 3 horses (2 Standardbreds and 1 Thoroughbred) caused joint enlargement and lameness. Fragments were removed by use of arthroscopy. Accurate placement of the arthroscope into the dorsal joint space was necessary to obtain an adequate view of the fragments. After surgery, 2 of the horses resumed racing without joint problems, and the third was in training to race. High-detail radiographs are necessary to detect osteochondral fragments in horses with joint enlargement or lameness localized to the proxima...
Smith BL, Jones JH, Carlson GP, Pascoe JR.To determine whether body direction in a trailer affects the degree to which a horse is excited (and presumably stressed) during transport, heart rates were measured in 8 Thoroughbred geldings transported over a 32-km route of county roads while tethered facing forward or backward in a 4-horse stock trailer. Heart rates also were measured on the horses while they were tethered facing forward or backward in the same trailer while it was parked. Heart rates decreased during the first 10 minutes for both groups, and remained stable after the first 15 minutes. Heart rates were not significantly di...
Moore KH, Dunbar BS, Bousfield GR, Ward DN.Inhibin has been characterized from a number of mammals; however, it has not been extensively studied in horses. Western blot analysis was used to examine the size heterogeneity of equine inhibin alpha- and beta-subunits. The distribution of equine inhibin activity from the initial sizing column (S-200, 25 x 94 cm) indicated that the majority of equine inhibin activity was present as larger-molecular-size forms. When the large forms were analyzed by Western blot in nonreducing conditions, alpha-subunit bands were detected at 40,000 M(r), 56,000 M(r), 80,000 M(r), and 90,000 M(r); beta a reacti...
Zinkl JG, Madigan JE, Fridmann DM, Kabbur MB, Reynal-O'Connor J, Andresen JW.Five Thoroughbred and Quarter Horse cross foals were given 20 micrograms canine recombinant granulocyte-colony stimulating factor (rcG-CSF) per kg bwt intramuscularly (i.m.) on the day of birth and 10 micrograms rcG-CSF/kg for 13 additional days. During this time and for an additional 21 days haematology, bone marrow and clinical chemical analyses were performed. After one day of rcG-CSF administration leucocyte and neutrophil counts increased from 9.16 x 10(9)/l to 23.44 x 10(9)/l and from 6.45 x 10(9)/l to 19.61 x 10(9)/l, respectively. The counts continued to increase for the next 3-4 days ...
Von Wittke P, Lindner A, Deegen E, Sommer H.In this study the effects of training history on the results of a standardized two-speed test in competing Thoroughbreds were investigated during a racing season. For nine Thoroughbreds, 1,755 training days were recorded. Within the observation period each horse completed a two-speed field test at intervals of 6-8 wk to determine its running velocity (v) eliciting blood lactate concentrations of 4 (v4) and 12 mmol/l (v12). Horses performed 29 two-speed tests. Changes of v4 and v12 in a horse between two consecutive tests were used to assess effects of training history variables calculated for ...
Hendrickson DA, Nixon AJ, Grande DA, Todhunter RJ, Minor RM, Erb H, Lust G.Cartilage resurfacing by chondrocyte implantation, with fibrin used as a vehicle, was examined in large (12 mm) full-thickness articular cartilage defects in horses. Articular chondrocytes, isolated from a 9-day-old foal, were mixed with fibrinogen and injected with thrombin, in a 1:1 mixture, into 12 mm circular defects on the lateral trochlea of the distal femur of eight normal horses. The contralateral femoropatellar (knee) joint served as a control in which the defect was left empty. Synovial fluid from the femoropatellar joints was sampled on days 0, 4, 7, 30, 120, and 240 postoperatively...
Frankeny RL, Johnson PJ, Messer NT, Keegan KG, Corwin LA.A 7-month-old Appaloosa foal had bilateral hind limb lameness and was unable to rise from recumbency without assistance. Lameness could be exacerbated by tarsal flexion and a firm swelling at the distomedial aspect of the tibias was associated with a marked pain response when palpated. Radiography revealed enlargement of the distal tibial metaphysis physis (compared with normal), and radiolucent fissure lines extending proximally from the physis into the metaphysis at its medial aspect. Treatment included rest and dietary adjustment. Although clinical signs initially resolved following treatme...
Orme CE, Dunnett M, Harris RC.The primary aim of this study was to examine the within-day variation in the concentration of total and individual long chain free fatty acids (C > 14) in normally fed horses. Plasma samples were collected over a 24 h period from 12 resting horses during three separate sessions (six horses in the first session and three in the second and third). Samples were analysed for individual long chain free fatty acids (FFA) and glucose. During normal feeding, the predominant FFA in plasma were palmitic (C16:0), linoleic (C18:2), oleic (C18:1), stearic (C18:0) and linolenic (C18:3). Together these ac...
Zicker SC, Rogers QR.Temporal changes, as well as differences in distribution, in concentrations of 24 amino acids in plasma and whole blood of neonatal foals were determined from birth to 2 days of age. In addition, differences in concentrations of amino acids in plasma between mare and foal pairs were determined at birth. Significant (P < 0.05) hypoaminoacidemia existed for 15 amino acids in plasma of foals at birth, compared with mares (paired t-test). Concentrations of 7 amino acids (aspartate, glutamate, glutamine, glycine, hydroxyproline, phenylalanine, proline) in plasma of foals were higher (P 0.05). S...
Buechner-Maxwell V, Zhang C, Robertson J, Jain NC, Antczak DF, Feldman BF, Murray MJ.Leukemia is a neoplastic disease of one or more of the cell types of the hemopoietic system and is rarely diagnosed in the horse. This report describes a case of subleukemic acute myelomonocytic leukemia in an 11-year-old gelding. Preliminary cytological diagnosis was supported by two types of laboratory investigations. Cytochemical characterization of blood and bone marrow neoplastic cells was consistent with a myelomonocytic origin. Neoplastic blast cells in peripheral blood were labeled by monoclonal antibodies specific for cell surface molecules of horse granulocytes, but they were not lab...
Whalen LR, Wheeler DW, LeCouteur RA, Yovich JV, Boggie LC, Grandy JL, Kainer RA.Maximal conduction velocities of compound action potentials evoked by stimuli of 2 times threshold in the caudal cutaneous sural (CCSN) and medial cutaneous antebrachial (MCAN) nerves were determined by averaging potentials evoked and recorded through percutaneous needle electrodes. Mean maximal conduction velocities of compound action potentials were: CCSN = 61.3 +/- 2.0 meters/second (m/s) and MCAN = 56.4 +/- 2.8 m/s. To confirm accuracy of our percutaneous recordings, compound action potentials were recorded through bipolar chlorided silver electrodes from the exposed surfaces of fascicles ...
Wilson AM, Goodship AE.Mathematical modelling of tendon thermodynamics predicted that the temperature of the central core of the equine superficial digital flexor tendon would plateau at 11 degrees C above the tendon surface temperature during a sustained gallop. A mean temperature differential (between tendon core and surface) of 5.4 (S.E. +/- 1.0) degrees C was demonstrated in vivo in four horses. Peak intra-tendinous temperatures in the range 43-45 degrees C were recorded. Temperatures above 42.5 degrees C are known to result in fibroblast death in vitro [Hall (1988) Radiobiology for the Radiologist, 3rd Edn., pp...
McD￮ LA, Stover SM, Taylor KT, Les CM.The compressive, bending and torsional mechanical properties of osteotomized adult equine tibiae stabilized with an interlocking intramedullary nail (nail-tibia composite) were compared with those of intact tibiae to determine the clinical applicability of the the nail for repair of tibial fractures in adult horses. The mean yield load, failure load, and stiffness for the nail-tibia composites were significantly less (P < .05) than those for the intact tibiae in all loading configurations. The mean compressive yield load for the nail-tibia composites was greater than the compressive load ca...
Freeman DE, Donawick WJ, Klein LV.The effect of a single ligature on back pressure in the internal carotid artery was studied in nine horses. In six anesthetized horses, one internal carotid artery was catheterized 2 cm from its origin and blood pressure was recorded continuously. Then the artery was ligated, pressure was recorded again, and the horses were euthanatized. In another three anesthetized horses, indwelling catheters were placed in both internal carotid arteries and a loose ligature was placed proximal to one catheter. After horses recovered from anesthesia, the ligature was tied and blood pressure was recorded in ...
Bernoco MM, Liu IK, Willits NH.Six foals were deprived of colostrum for the first 36 hours after birth and, instead, received reconstituted powdered milk. Five control foals suckled their dams naturally. Blood samples were obtained from all the foals after birth and at approximately weekly intervals until at least 5.5 months of age. Sera were analyzed for hemolytic complement activity, complement component C3, and correlating IgG concentration. Hemolytic complement (P = 0.0145) and C3 (P = 0.0002) values were significantly higher in colostrum-deprived foals (CDF) than in naturally nursed foals at 2 to 5 days of age. In addi...
MacDonald DG, Morley PS, Bailey JV, Barber SM, Fretz PB.Post operative surgical wound infection rates were determined 452 cases of equine orthopaedic surgery performed at the Western College of Veterinary Medicine, Saskatoon, Saskatchewan, between January 1, 1981 and December 31, 1990. Only surgical procedures classified as clean or clean-contaminated by the National Research Council were included in this study. The overall post operative infection rate was 10.0% (45 of 452). Clean surgeries (n = 433) had an 8.1% infection rate while clean-contaminated surgeries (n = 19) had a 52.6% infection rate. Information collected from the medical records was...
Sandersen C, Ceusters J, Fourez A, Tosi I, Graide H, Lejeune JP, Serteyn D.Recurrent laryngeal neuropathy (RLN) commonly affects horses and is characterized by abnormal respiratory sounds and exercise intolerance. The recurrent laryngeal nerve shows lesions of demyelination. The benefit of applying stem cells to demyelinated nerves has been demonstrated in various animal models. The aim of the study was to test the feasibility and safety of a peri-neuronal injection of autologous muscle-derived mesenchymal stem cells to the left recurrent laryngeal nerve in healthy horses by using an electrical nerve stimulator. Muscle-derived stems cell are obtained from five health...
Rubio-Martínez LM, Carstens A.Increased intraosseous pressure (IOP) is a well-characterized source of pain in humans that can be successfully treated by medullary decompression. This report describes the clinical and diagnostic findings, treatment and successful outcome of a horse with a four week long, non-weight bearing lameness secondary to suspected traumatically-induced increased IOP in the left radius. Scintigraphic examination characterized by severe increase in radiopharmaceutical uptake within the affected radius aided in the initial localization of the source of lameness. Decompression of the affected radius was ...
Waterman A.Disturbances of fluid and electrolyte balance may occur in the horse as a consequence of many disease processes. Disorders may be classified into 3 main categories, primary water loss, mixed water and electrolyte depletion and acid base disturbances. This paper reviews the changes which occur with each type of disorder and discusses methods of diagnosis and assessment of such imbalances. The principles of treatment are described and the management of fluid replacement therapy in 3 of the disorders, mainly acute intestinal obstruction, inability to drink and diarrohea is discussed.
Greet TR, Jeffcott LB, Whitwell KE, Cook WR.The paper describes the assessment and practical implications of a laryngeal adductory reflex in a series of 30 ataxic and 64 non-ataxic horses. The reflex was evoked by slapping the saddle region just caudal to the withers. In normal horses this produced a flickering adductory movement of the contralateral arytenoid cartilage which was observed endoscopically. Abolition of the laryngeal response was encountered in in 3 situations:--(1) Disruption of the afferent impulse occurred in those horses in which there was significant spinal cord pathology affecting the pathway from the cranial thoraci...
Ríha J, Minár J, Skaloud J, Janes K, Králík O.Dipterous blood-sucking insects (horseflies, black flies, gnats, midges) have negative impacts on the performance of draught horses in forest enterprises. For the protection of these animals, the following preparations were applied at the interval of 24 hours: diethyltoluamide, Oxamat (N,N-diethyloxamine acid, USSR) and Stomoxin (synthetic pyrethroid, product of the firm Wellcome, England). In the course of 66 working days, the performance of test animals treated with 10% water emulsion of diethyltoluamide increased by 49.25 cu. m. of skidded wood, i.e. by 0.74 cu. m. wood per horse/day (21.65...
Hawkins DL, Stover SM.To investigate the effect of late gestation, age, and parity on material properties of third metacarpal (MCIII) cortical bone in mares. Methods: 8 healthy mares (treatment group) that died or were euthanatized within 24 hours after parturition because of foaling complications and 6 age-matched, healthy, nonpregnant mares (control group). Methods: After random assignment for mechanical testing and microradiography, the dorsal half of transverse mid-diaphyseal sections of each MCIII bone was divided into lateral, dorsal, and medial regions. Cylinders of bone from each of the 3 regions were teste...
Azizi S, Masoudi H.Colic is a clinical syndrome and has been defined as a visceral abdominal pain and/or acute abdominal disease. It is a common cause of morbidity and mortality in horses. The most common forms of colics are related to gastrointestinal tract in nature and most often linked to colonic disturbances. However, colics are not well understood in donkeys compared to those of in horses and the literature is poor regarding bowel strangulating obstruction in donkeys. This report described the clinical signs and post-mortem necropsy findings of an abdominal colic due to the left colon volvulus following a ...
Norman TE, Chaffin MK, Bisset WT, Thompson JA.To characterize the associations between clinical signs of nasopharyngeal cicatrix syndrome (NCS) and endoscopic findings in horses. Methods: Retrospective, case-control study. Methods: 239 horses (118 case horses and 121 control horses). Methods: Medical records of horses that had an endoscopic evaluation of the upper airway performed between January 2003 and December 2008 were reviewed. Clinical signs and the appearance and anatomic locations of lesions identified during endoscopic evaluation were reviewed and recorded for each horse. The associations between clinical signs and endoscopic fi...
Semevolos SA, Nixon AJ, Goodrich LR, Ducharme NG.To determine clinical and radiographic findings in and treatment and outcome of large animals with shoulder joint luxations. Methods: Retrospective study. Methods: 5 horses, 3 goats, 1 calf, 1 sheep, 1 Himalayan tahr, 1 pot-bellied pig, 1 reindeer, and 1 white-tailed deer. Methods: Medical records and radiographs were reviewed to determine signalment, history, physical examination findings, type of luxation, treatment, and outcome. Owners and referring veterinarians were contracted for follow-up information. Results: Goats, sexually intact males, and animals < 1 year old were overrepresente...
Hu Z, Zhu C, Chang H, Guo W, Liu D, Xiang W, Wang X.The objective of this study was to develop a novel EvaGreen (EG) based real-time PCR technique for the simultaneous detection of Equine herpesvirus 1 (EHV-1) and Equine herpesvirus 4 (EHV-4) genomes from equine nasal swabs. Viral genomes were identified based on their specific melting temperatures (T m), which are 88.0 and 84.4 °C for EHV-1 and EHV-4, respectively. The detection limitation of this method was 50 copies/μl or 0.15 pg/μl for EHV-1 and 5 copies/μl or 2.5 fg/μl for EHV-4. This assay was 50-1,000 times more sensitive than the SYBR Green (SG)-based assay using the same primer...
Koch DW, Easley JT, Nelson BB, Delcambre JJ, McCready EG, Hackett ES.Auditory tube diverticula, also known as guttural pouches, are naturally occurring dilations of the auditory tube in horses that communicate with the nasopharynx through a small ostium. Infection and select other conditions can result in inflammation and narrowing of the nasopharyngeal ostium, which prevents drainage of fluid or egress of air and can lead to persistent infection or guttural pouch tympany. Auditory tube diverticulotomy allows continuous egress from the auditory tube diverticula and is a feature of disease treatment in horses, in which medical treatment alone is not successful. ...
Wilson BD, Neal RJ, Howard A, Groenedyk S.Standardbred pacers were studied at four different nominated speeds and selected gait kinematics were analysed to determine factors which contribute to pacing speed. A deterministic model is proposed in which pacing speed is a function of stride length and stride timing variables. Stance length and suspension time remained relatively constant over the different pacing speeds. Variables which discriminated best between pacing speeds were suspension length and overlap time. At near maximal speed, the pacers increased speeds with increased stride length. This was attributed to an increased suspen...
Winter J, Kershaw O, Schmitz R, Gehlen H.Equine leukaemic lymphoma is a rare disease of the haematopoetic tissue. It results from neoplastic degradation of B- and T-lymphocytes and their occurrence in the blood. Clinical signs are often unspecific and include chronic weight loss, ventral oedema at the thorax and abdomen and regional lymphadenopathy. Horses are often presented late in the course of the disease and therapy is rarely successful. This review summarizes the clinical pathologic findings of equine leukaemic lymphoma and the findings of laboratory testing and other diagnostic measures, and presents treatment options describe...
Reynolds BL, Stedham MA, Lawrence JM, Heltsley JR.A space-occupying intracranial mass was diagnosed in a horse. The clinical findings included blindness, circling to the right, apprehension, anorexia, weight loss, and leaning against the stall. On ophthalmoscopic examination, the most striking observation was complete bilateral devascularization of the retinas. The horse was euthanatized and necropsied. Necroscopy revealed the mass to occupy the olfactory and frontal areas of the left hemisphere of the brain and part of the left frontal sinus. Microscopically, the mass was an adenocarcinoma and probably arose from the lining epithelium of the...
Verwilghen D, Ponthier J, Van Galen G, Salciccia A, Sandersen C, Serteyn D, Grulke S.Radial extracorporeal shockwave therapy (ESWT) is widely used in equine practice for the treatment of orthopedic problems. However, its original use as a lithotripsy device in human and canine urology led us to postulate that it could be used as an alternative to the surgical treatment of urethral calculi in horses. Objective: Radial ESWT can easily and safely fragment calculi in the distal urethra of the horse. Methods: Two postmortem cases and 1 live case of obstructive urinary disease admitted at the Veterinary Teaching Hospital of Liege. Methods: A radial shockwave device was directly appl...
Archer RM, Gordon SJ, Carslake HB, Collett MG.A 3-month-old female Warmblood foal was presented after displaying signs of colic with pyrexia for 5 days. Results: The foal continued to show signs of colic, frequently passed urine, and was pyrexic with an elevated white blood cell count. The umbilical stalk was thickened but there was no evidence of purulent material. Exploratory laparotomy revealed an enlarged left umbilical artery remnant tightly adhered to the bladder wall. The left umbilical artery continued to an aneurysm involving the distal aorta. The foal was subject to euthanasia and post-mortem examination confirmed a spherical ao...
Houpt KA.In summary, horses spend 60% or more of their time eating when grazing or when feed is available free choice. Grasses are their preferred food, but they supplement the grass with herbs and woody plants. Sweetened mixtures of oats and corn are the most preferred concentrate. Horses can increase or decrease the time spent eating and amount eaten to maintain caloric intake. Their intake is stimulated by drugs such as diazepam and by the presence of other horses. Horses stop eating when gastric osmolality increases; increases in plasma osmolality, protein, and glucose accompany digestion. Foals ea...
Gabriel CR, Marta P.A two-month-old, Spanish breed, foal was referred with right hind limb lameness of two weeks duration. Clinical examinations confirmed a complex combination of lesions within the lateral femorotibial joint, including a subchondral bone cyst in the lateral femoral condyle, a severe popliteal tendonitis, and a delayed cartilage detachment of the lateral femoral condyle. Because of the complex association of these lesions, poor prognosis for an athletic career was given to the owner. Four years later, the filly is pasture sound. Lesions of the popliteal tendon in the horse are uncommon. The popli...
Del Piero F, Wilkins PA, Timoney PJ, Kadushin J, Vogelbacker H, Lee JW, Berkowitz SJ, La Perle KM.A case of fatal nonneurological equine herpesvirus 1 (EHV-1) infection in a yearling filly is described. Gross lesions included extensive pulmonary edema, prominent laryngeal lymphoid follicles, and congestion and edema of the dorsal third ventricle choroid plexus. Histologically, there was vasculitis, hemorrhage, and edema in the lungs and dorsal third ventricle choroid plexus as well as mild intestinal crypt necrosis with occasional intranuclear inclusion bodies. The perivascular and vascular inflammatory infiltrates were comprised mainly of T lymphocytes and macrophages. EHV-1 antigen was i...
Roska S, Morello S, Rajamanickam V, Smith LJ.Effects of lactated Ringer's solution (LRS) and hetastarch 130/0.4 (HES) on colloid osmotic pressure (COP), plasma osmolality (OSM) and total protein (TP) were investigated in 18 inhalational-anaesthetised healthy horses. Horses received 4-6 ml/kg LRS (LRS; n=9) or HES (HES; n=9) from anaesthesia induction through 60 min, after which all were administered LRS. COP, TP and OSM were measured before premedication (baseline), postinduction and 30 (n=18), 60 (n=18), 90 (n=18) and 120 (n=12) minutes. Baseline COP, OSM and TP were not different between groups. TP decreased in both groups at all t...
Naylor JM, Wolker RE, Pharr JW.Twenty students and 16 diplomates listened to 7 recordings made from 7 horses with either aortic (n = 3) or mitral valve (n = 4) regurgitant murmurs. A total of 30 different terms were used to describe the character of these murmurs. However, only 4 terms were used in a repeatable and consistent manner. Most people described the character of a given mitral or aortic valve murmur with 1 or 2 terms. Diplomates drew from a pool of terms that was about half the size of that used by students--8.1 +/- 2.0 terms for diplomats (mean +/- 1 SD) versus 13.1 +/- 1.8 terms for students (P > .001). Only blo...
Steinman A, Sutton GA, Elad D.Rhodococcus equi is an important pathogen in young horses. In recent years it has been increasingly recognized as an opportunistic infectious agent in patients with immune deficiency. The increase in recognized cases may be related to the increased prevalence of AIDS. However, more cases may have been recognized lately due to increased awareness of the pathogenicity of this bacterium. Based on medical reports, there appears to be an association between Rhodococcus equi infections and exposure to animals, horses in particular. During the past year, 2 cases of rhodococcus pneumonia were diagnose...
Vercelli C, Tursi M, Miretti S, Giusto G, Gandini M, Re G, Valle E.Laminitis is one of the most devastating diseases in equine medicine, and although several etiopathogenetic mechanisms have been proposed, few clear answers have been identified to date. Several lines of evidence point towards its underlying pathology as being metabolism-related. In the carbonyl stress pathway, sugars are converted to methylglyoxal (MG)-a highly reactive α-oxoaldehyde, mainly derived during glycolysis in eukaryotic cells from the triose phosphates: D-glyceraldehyde-3-phosphate and dihydroxyacetone phosphate. One common hypothesis is that MG could be synthesized during the dig...
Valdés-Martínez A, Seiler G, Mai W, Bolt DM, Mudge M, Dukti SA, Hubert JD.To develop a quantitative method of interpreting tibial scintigrams of Thoroughbred racehorses with tibial stress fractures that may facilitate diagnosis of fractures and to provide prognostic information regarding future performance of affected horses. Methods: 35 Thoroughbred racehorses. Methods: Static bone-phase scintigrams of tibial stress fractures were quantitatively analyzed by use of ratios of the mean radionuclide counts per pixel in a region of interest (ROI) drawn around the area of increased uptake of radiopharmaceutical to mean counts per pixel in a second ROI drawn around an app...
De Martin I, Theoret CL.To describe immunolocalization of TGF-beta receptors (RI and RII) in normal equine skin and in thoracic or limb wounds, healing normally or with exuberant granulation tissue (EGT). Methods: Group A: six wounds on one metacarpus and one midthoracic area. Group B: six wounds on both metacarpi, one of which was bandaged to stimulate EGT. Immunohistochemistry was used to detect RI and RII expression in wound margins. Methods: Eight horses, randomly assigned to one of two study groups. Methods: Neutralizing polyclonal anti-rabbit RI and RII antibodies were used to detect spatial expression of RI an...
Kinoshita Y, Niwa H, Uchida-Fujii E, Nukada T.The incidence of equine proliferative enteropathy, caused by Lawsonia intracellularis, is increasing around the world. To investigate the relationships of variable-number tandem repeat (VNTR) patterns with host species and clinical status in horses, multilocus VNTR analysis (MLVA) was applied to 98 L. intracellularis samples collected from horses, seven from pigs, seven from wildlife, one vaccine strain, and 17 public strains. The VNTR patterns were highly diverse: a total of 130 samples identified 99 distinct patterns, and the 98 horses were classified into 71 different patterns. A phylogen...
Baird DH, Pilsworth RC.Anecdotal evidence suggested that many cases of third tarsal bone (T3) fracture encountered clinically were associated with an abnormal shape to this bone. The radiographs of 10 normal horses and 10 horses affected with slab fracture of T3 were therefore examined to ascertain if any pre-existent radiological abnormality was present in cases of fracture. Measurement of the maximum and minimum width between the proximal and distal articular surfaces of the dorsolateral aspect of this bone was carried out on a standardised dorso-50 degrees medial-palmarolateral radiographic projection of the tars...
Dik KJ, van den Belt AJ, Keg PR.The diagnosis of restriction of free movement of the flexor tendons through the fetlock canal usually rests on the characteristic clinical appearance of this condition, or airtendography. In a series of seven normal Warmblood horses and 16 diseased horses of various breeds, the efficacy of ultrasonography in the diagnosis of this condition was determined. In normal limbs, the annular ligament is a very thin structure usually not visible on sonograms. In diseased limbs, ultrasonography outlined flexor tendon injury, distension and thickening of the digital sheath, peritendovaginal tissue prolif...
Sargent SJ, Frank LA, Buchanan BR, Donnell RL, Morandi F.Otoscopic examination and cytology of the equine ear would be beneficial in diseases such as head trauma, headshaking, otitis externa secondary to otitis media, vestibular disease, aural neoplasia and aural pruritus secondary to parasites. In practice, otic examinations of horses are rarely done due to the perceived difficulty in visualizing the equine external ear canal and tympanic membrane, as well as the need for chemical restraint. In this study, the proximal external ear canal was examined in live horses using a handheld otoscope and in cadaver heads using video otoscopy. Visualization o...
