Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Rakestraw PC, Snyder JR, Woliner MJ, Sanders KM, Shuttleworth CW.To evaluate the role of nitric oxide (NO), vasoactive intestinal peptide (VIP), and a transmitter acting through an apamin-sensitive mechanism in mediating inhibitory transmission in the equine jejunal circular muscle, and to determine the distribution of VIP-and NO-producing nerve fibers in the myenteric plexus and circular muscle. Methods: Circular muscle strips were suspended in tissue baths containing an oxygenated modified Krebs solution and attached to isometric force transducers. Responses to electrical field stimulation (EFS), tetrodotoxin, the NO antagonists L-N-nitro-arginine-methyl-...
Baxter GM.Orthopedic infections-those involving bones, joints, tendon sheaths, or bursae-are some of the most difficult problems for equine surgeons to treat successfully. Sources of the infection are usually hematogenous, traumatic, or iatrogenic and knowledge of the most likely causative bacteria is very useful in selecting the most appropriate antimicrobial(s) to either prevent or treat these infections in horses. This article discusses the clinical findings, diagnosis, treatment, and prevention of orthopedic infections in horses. More recent treatment methods such as synovial drainage techniques (ar...
Ruggles AJ, Moore RM, Bertone AL, Schneider RK, Bailey MQ.To determine clinical signs, radiographic and scintigraphic findings, and performance outcome of racing Standardbreds with tibial stress fractures. Methods: Retrospective case series. Methods: 13 racing Standardbreds with tibial stress fractures. Methods: Information concerning clinical signs, diagnostic evaluation, and recommendations was obtained by review of the medical records. Performance information before and after diagnosis of the fracture was collected from racing records, and follow-up information was obtained from the owners or trainers by use of a telephone questionnaire. Results: ...
Yu MF, Ewaskiewicz JI, Adda S, Bailey K, Harris V, Sosnoski D, Tomasic M, Wilson J, Kotlikoff MI.We report adenovirus-mediated gene transfer into airway smooth muscle cells in cultured cells and organ-cultured tracheal segments. Incubation of cultured rat tracheal myocytes with virus (5 x 10(8) pfu/ml) for 6 h resulted in beta-galactosidase expression in 94.8 +/- 2.5% of cells (n = 4). Following incubation of thin (less than 200 microns diameter) equine trachealis muscle segments with virus in organ culture (5 x 10(8)-5 x 10(10) pfu/ml) the average expression of the Lac Z gene was approximately 19 +/- 10% (n = 9). Expression was markedly improved, however, in segments from neonatal rats (...
Clayton HM.The success of a clinical gait laboratory depends on choosing the right equipment, installing it correctly, running calibration checks, and having skilled technical and professional personnel. For kinematic analysis, videographic or optoelectronic systems are the method of choice, with 2-D data being adequate for the majority of equine evaluations. A force plate provides a precise description of the 3-D ground reaction force; transmission of the force through the body tissues is measured using strain gauges attached to the bones and tendons. Accelerometers bonded to the hoof wall provide infor...
Martin RB, Gibson VA, Stover SM, Gibeling JC, Griffin LV.In studying the flexural fatigue properties of the equine third metacarpal (cannon) bone, we previously found that the dorsal region was weaker monotonically, but more fatigue resistant, than the lateral region. Fatigue resistance was associated with fracture surfaces which demonstrated that secondary osteons had "pulled out" of the surrounding matrix; this never happened in lateral specimens. We therefore became interested in the osteonal structure of this bone, and began to study its birefringence patterns in circularly polarized light. We found that the predominant type of secondary osteon ...
Palmer SE.The carbon dioxide laser has become an important surgical instrument in human and veterinary medicine. The unique properties of this laser make it the instrument of choice for precise incision, coagulation, and vaporization of tissue at the body surface with minimal morbidity to the patient. This article describes the instrumentation and techniques used to perform a variety of equine general surgical procedures with the carbon dioxide laser. The benefits of surgery using the carbon dioxide laser include precise dissection with minimal trauma to adjacent tissues, good hemostasis, and the abilit...
Moore RM, Charalambous AC, Masty J.To measure colonic arterial (CA) and colonic venous (CV) plasma neuropeptide concentrations during low-flow ischemia and reperfusion of the large colon in horses. Methods: 10 adult horses. Methods: CA and CV plasma samples collected from anesthetized horses during experimentally induced low-flow colonic ischemia and reperfusion were assayed for vasoactive intestinal polypeptide (VIP), calcitonin gene-related peptide (CGRP), and substance P (SP), using radioimmunoassays. In 6 anesthetized horses, colonic ischemia (20% of baseline (BL]) was maintained for 3 hours, then blood flow was restored an...
Goel S, Schumacher J, Lenz SD, Kemppainen BW.Disruption in sphingolipid (SL) metabolism is a biomarker of exposure to fumonisins. The role of altered SL metabolism in the pathogenesis of fumonisin toxicoses is not understood. A 27-d feeding trial in horses compared the toxic effects of 3 strains of Fusarium moniliforme: RRC 415, cultured from corn in MS; AU 2/3, cultured from feed associated with clinical signs of duodenitis-proximal jejunitis (DPJ) in horses in AL; and MRC 826, cultured from corn in South Africa and shown to cause equine leukoencephalomalacia (ELEM). These were cultured on corn and diluted with clean corn and grain mixe...
Kane AJ, Stover SM, Gardner IA, Case JT, Johnson BJ, Read DH, Ardans AA.To evaluate selected shoe characteristics as risk factors for fatal musculoskeletal injury (FMI) and specifically for suspensory apparatus failure (SAF) and cannon bone condylar fracture (CDY) of Thoroughbred racehorses in California. Methods: Case-control study. Methods: Thoroughbred racehorses (n = 201) that died of were euthanatized at California racetracks between August 1992 and July 1994. Methods: Shoe characteristics were compared between case horses affected by FMI (155), SAF (79), and CDY (41) and control horses that died for reasons unrelated to the appendicular musculoskeletal syste...
Bowling AT, Byrns G, Spier S.The pedigree origin of a base pair substitution in the horse muscle sodium channel gene that confers susceptibility to the muscle disease hyperkalemic periodic paralysis (HYPP) was investigated with a set of 978 Quarter Horses. The horses were chosen at random, based on a collection of blood samples taken between 1989 and 1991 to meet parentage testing requirements, primarily but not exclusively from breeding stallions. The frequency of Quarter Horses positive for the base pair substitution, all heterozygotes, was 4.4%, which corresponds to an allelic frequency of 0.02. All horses positive for...
Kane AJ, Stover SM, Gardner IA, Case JT, Johnson BJ, O'Brien MJ, Read DH, Ardans AA.To develop a standard technique for evaluation of racehorse shoes, to assess homotypic variation (interlimb variation) in shoe characteristics, and to determine whether shoe characteristics varied with age and sex. Methods: Cross-sectional study. Methods: Thoroughbred racehorses (n = 201) that died or were euthanatized at California racetracks between August 1992 and July 1994. Methods: Shoe characteristics were measured on horses examined after death. Percentage of agreement was used to compare shoe characteristics between limbs (homotypic variation). Using chi 2 analysis, shoe characteristic...
Wilde H, Thipkong P, Sitprija V, Chaiyabutr N.Active immunization against infectious disease is important. However, much of our world faces poverty, social injustice, and warfare, all of which cause universal immunization to remain a distant dream. Agents that provide passive immunity thus remain essential biologicals. The most important of these are human or equine antisera against rabies, tetanus, diphtheria, and snake antivenins. Homologous products are either unavailable or unaffordable in places where they are needed the most. Less expensive heterologous (equine) antisera can be purified and are safe to use, but these antisera are al...
Wilson DA, Adelstein EH, Keegan KG, Barrett BA, Kutz RR.To determine whether monokines produced by activated rabbit peritoneal macrophages can inhibit development of exuberant granulation tissue formation in distal limb wounds in ponies. Methods: Randomized block. Methods: 5 castrated male ponies, 2 to 6 years old and weighing 140 to 190 kg. Methods: In vitro activity of cell-free rabbit peritoneal macrophage supernatant was determined after incubation of fibroblasts from the flank and the distal portion of limbs of horses and ponies. Tritiated thymidine was then added, and after reincubation, radioactivity was measured. After creation of a 4-cm2, ...
Peham C, Scheidl M, Licka T.The aim of this paper is to present a method of signal processing necessary for motion analysis in the trotting horse. Motion analysis is widely used to assess lameness in horses. By definition, lameness in trot is present if the movements during the stance phases of both fore or hind limbs differ. The motion of the horse is recorded using a system for motion analysis (Selcom, 1983, SELSPOT II User Manual, Pad Nr. 6710) and the vertical motion of the head during both stance phases is compared. The symmetry is analyzed comparing the values of the Fourier coefficients. Additional head movements ...
Douglas JE, Mittal C, Thomason JJ, Jofriet JC.During normal weight-bearing and locomotion, the equine hoof wall deforms in a consistent pattern; the proximal dorsal wall rotates caudo-ventrally about the distal dorsal border and there is latero-medial flaring posteriorly. The aim of this study is to examine whether there are regional differences in the modulus of elasticity of hoof wall material and whether such differences correlate with the pattern of deformation which occurs in vivo. The modulus of elasticity of equine hoof wall was determined in tension and compression for samples from six forefeet. Samples were tested at the mid-poin...
Kawcak CE, Baxter GM.Recent innovations in surgical materials have helped to enhance wound healing and protect surgical wounds from infection. Materials such as polyglyconate have been evaluated in equine tissues and found efficacious. Other materials, such as poliglecaprone 25, appear to have qualities useful to equine surgery but are untested in equine tissues. Care must be taken to fully evaluate a new surgical material because its usefulness in equine tissues may not match that in human or laboratory animal tissues. Furthermore, use of disposable materials in surgery, although considered ideal for maintenance ...
Bell KS, Philp JC, Christofi N, Aw DW.Two regions in the gene coding for 16S rRNA in Rhodococcus equi were selected as species-specific primer sequences for the polymerase chain reaction (PCR). PCR using these primers was tested against 10 strains of R. equi (including the type strain) and gave positive results for all but was negative for all other tested species of Rhodococcus; representatives of the most closely related genera and a number of other bacterial species. This method could therefore be used to identify this species which can infect the lungs or other organs of horses, pigs, humans and other animals.
Bada R, Mittal KR, Higgins R.A total of 50 Actinobacillus suis isolates were studied for their biochemical and antigenic characteristics. Of them, 40 isolates originated from different tissues of diseased pigs, and the other ten isolates were from horses with respiratory problems. There was no major biochemical difference among equine and porcine A. suis isolates. Results of tube agglutination tests showed that porcines isolates were antigenically homogeneous while equine isolates were heterogeneous.
Hendrickson DA, Wilson DG.Equine surgery continues to benefit from advances in laparoscopic techniques. Descriptions of the normal anatomy of the standing horse and advances in instrumentation have improved our ability to perform laparoscopic surgery in both standing and dorsally recumbent horses. The common uses for laparoscopy are diagnostic laparoscopy, cryptorchidectomy, ovariectomy, and diagnostic thoracoscopy. Other reported uses include inguinal hernia repair, ruptured bladder repair, and ventral colopexy.
Klee S, Nürnberger MC, Keller H, Ungemach FR.A therapeutical dose of kanamycin was tested intravenously and intramuscularly in four normal standardbreds and plasma concentrations were measured over a 12 hour period. Plasma levels exceeded a minimum inhibitory concentration of 4 micrograms/ml within only 15 minutes for 8 hours both after i.v. and i.m. injection. Kanamycin revealed a mean plasma half life of 2.3 hours. Bioavailability of an intramuscular dose was about 76%. The pharmacokinetic parameters demonstrate the rapid onset of antibacterial plasma levels of the test compound. A dose regimen for horses of two times daily 5 mg/kg bod...
Paré J, Carpenter TE, Thurmond MC.To determine whether clustering existed in the spatial or temporal distribution of horses that shed Salmonella krefeld in their feces during hospitalization. Methods: Retrospective analysis of medical records. Methods: 219 horses housed in the intensive care unit of a veterinary medical teaching hospital from October 1991 through May 1992. Methods: Bacteriologic culturing of fecal samples was used to identify horses shedding S krefeld. For affected horses, the scan statistic was used to analyze temporal clustering, and Knox's method was used to analyze temporal-spatial clustering. Results: 20 ...
Trotter GW, McIlwraith CW.Surgical procedures completed under arthroscopic guidance have become commonplace in many equine practices and have largely replaced surgery using arthrotomy incisions. With a limited amount of equipment, numerous diagnostic and surgical procedures can be completed. Surgeons need to become familiar with regional and intraarticular (intrasynovial) anatomy to ensure that proper surgical approaches are used, access to the lesion will be realized, and potential complications will be minimized. Specialized motorized instruments and surgical lasers are now available and may be useful in the treatmen...
Uzal FA, Woodman MP, Giraudo CG, Robles CA, Doxey DL.'Mal seco' is an almost invariably fatal disease of horses in Argentina and Chile, which resembles grass sickness, a dysautonomia of horses in Europe. The aetiology of mal seco remains unknown. An attempt to reproduce the disease was made by feeding horses with Festuca argentina, a plant considered to be toxic to animals and which was consistently found in the diet of nine horses suffering from mal seco. Three horses were fed with F argentina ad libitum for 28 days. The plant was infected with an endophytic fungus, whose morphological characteristics were in agreement with descriptions of Acre...
Friedman DS, Schoster JV, Pickett JP, Dubielzig RR, Czuprynski C, Knoll JS, Wolfgram LJ.The fungal organism Pseudallescheria boydii was isolated from the cornea of a Quarter Horse with ulcerative keratitis. Despite aggressive hourly medication through a subpalpebral lavage system, with drugs including miconazole and natamycin, the cornea developed a stromal abscess. Orbital exenteration was performed after 3 weeks. The fungal isolate was later determined to be resistant to all 8 antifungal drugs tested. Microscopic examination of the cornea revealed fungal hyphae throughout the corneal stroma and penetrating the Descemet membrane. Pseudallescheria boydii has not been implicated p...
Trenholme HN, Sakai DM, Berghaus LJ, Hanafi AL, Knych HK, Ryan CA, McHale B, Banovic F, Quandt JE, Barletta M, Reed RA. To evaluate changes in immunological parameters following subcutaneous (SC) and intramuscular (IM) administration of meperidine in horses through quantitative analysis of plasma tryptase, histamine, and IgE levels. Six adult horses were enrolled in a prospective randomized crossover design. Horses were administered one treatment per day, with a seven day washout period: (a) meperidine 1 mg/kg IM, saline 6 mL SC; (b) saline 6 mL IM, meperidine 1 mg/kg SC; (c) saline 6 mL SC, saline 6 mL IM. Blood samples were obtained for plasmatic histamine (baseline, 5, 10, 15, 30, and 60 min) via LC-MS/MS ...
López-Sanromán FJ, Freilich GM, Gomez-Cisneros D, Varela M, Santiago I, Manso-Díaz G.The objective of the present study was to compare, using accelerometry, the gait changes produced after administration of a dose of 0.2 mg/kg of morphine at the walk in healthy horses. Six mature horses were used, and all animals received two different treatments with, at least, two weeks interval in between. Treatments administered consisted of a single dose of 10 ml of saline solution or a total of 0.2 mg/kg of morphine diluted in 10 ml of saline solution. A three-dimensional accelerometric device was used to collect data continuously while horses were walking. The walking test was performed...
Valdez H, Clark RG, Hanselka DV.Flexible medical grade carbon fiber was surgically implanted in tenectomized or lacerated superficial and deep digital flexor tendons of 13 horses (7 clinical cases and 6 experimental), ranging in age from 15 months to 10 years and weighing 300 to 500 kg. The 6 experimental horses were euthanatized at 30-, 45-, 60-, and 90-day intervals for gross and histologic evaluation of the results. Three of the experimental horses served as their own controls. Of the 7 clinically affected horses, 3 were euthanatized because they developed laminitis or the wound failed to heal. The remaining 4 horses in t...
Huggons N.A Thoroughbred yearling was presented with neurological, radiographic, and myelographic abnormalities consistent with cervical vertebral stenotic myelopathy. Surgical correction was performed by using ventral cervical interbody fusion at 3 intervertebral spaces. The patient recovered uneventfully from surgery. The neurological status remained unchanged initially; however, significant improvement was noted 37 weeks postoperatively. Un Thoroughbred d’un an a été présenté avec des anomalies neurologiques, radiographiques et myélographiques compatibles avec une myélopathie sténosée des ...
Gadaj A, Ventura E, Healy J, Botrè F, Sterk SS, Buckley T, Mooney MH.Selective androgen receptor modulators (SARMs) represent non-steroidal agents commonly abused in human and animal (i.e. equine, canine) sports, with potential for further misuse as growth promoting agents in livestock-based farming. As a direct response to the real and possible implications of illicit application in both sport as well as food production systems, this study incorporated enzymatic hydrolysis (β-glucuronidase/arylsulfatase) into a previously established protocol while maintaining the minimal volume (200 µL) of urine sample required to detect SARMs encompassing various pharmacop...
Trim CM, Moore JN, Hardee MM, Hardee GE, Slade EA.Horses with colic may be endotoxaemic and subsequently develop hypotension during anaesthesia for surgical operation. The aim of this study was to evaluate the efficacy of dopamine as a means to improve cardiovascular function in anaesthetised endotoxaemic horses. Nine horses (five in group 1 and four in group 2) were anaesthetised with thiopentone and guaifenesin and anaesthesia was maintained with halothane. After approximately one hour, facial artery pressure, heart rate, pulmonary artery pressure, cardiac output, temperature, pHa, PaCO2, PaO2, base excess, packed cell volume, plasma protei...
Ellis KL, Barrett MF, Selberg KT, Frisbie DD.Pathology involving the oblique sesamoidean ligaments (OSLs) is commonly diagnosed during magnetic resonance imaging (MRI) of the equine distal limb. Presence of striations within the ligament and magic angle artefact can result in an incorrect diagnosis of pathological change. No studies have been performed using histopathology, the gold standard, to corroborate their imaging diagnosis. Objective: (a) To determine which MRI characteristics are associated with normal vs abnormal OSLs and (b) to evaluate the ability of MRI to correctly identify abnormal vs normal oblique sesamoidean ligaments u...
Frazer JL, Perkins NR, Pitt D.During the 2007 equine influenza (EI) outbreak, infected horses were quarantined at Morgan Park Recreational Grounds (MPRG) near Warwick, Queensland. Some individuals caring for horses were reported to have made return journeys between MPRG and home properties containing other horses during the time there was active infection at MPRG. Objective: A retrospective cohort study to assess the biosecurity and hygiene measures undertaken and their outcomes. Methods: All individuals recorded as being responsible for caring for one or more horses at MPRG, and who were also recorded on entry and exit lo...
Adolfsson KH, Sjöberg I, Höglund OV, Wattle O, Hakkarainen M.A resorbable 3D printed polydioxanone (PDO) device is manufactured to facilitate ligation of vascular tissue during surgery. The device must provide sufficient mechanical performance throughout the healing period. Therefore, degradation and mechanical performance of the device are investigated as a function of in vivo and in vitro aging. During aging the PDO device released cyclic and linear water-soluble products. In vivo aging resulted in higher relative number of linear oligomers in comparison to in vitro aging. A major loss of mechanical performance is observed after only 10 days in vivo a...
Dirikolu L, Karpiesiuk W, Lehner AF, Tobin T.Toltrazuril sulfone (ponazuril) is a triazine-based antiprotozoal agent with clinical application in the treatment of equine protozoal myeloencephalomyelitis (EPM). In this study, we synthesized and determined the bioavailability of a sodium salt formulation of toltrazuril sulfone that can be used for the treatment and prophylaxis of EPM in horses. Toltrazuril sulfone sodium salt was rapidly absorbed, with a mean peak plasma concentration of 2400 ± 169 (SEM) ng/mL occurring at 8 h after oral-mucosal dosing and was about 56% bioavailable compared with the i.v. administration of toltrazuril sul...
Petrov KK, Dicks LM.The aim of this study was to determine which of the two species, Fusobacterium necrophorum or Dichelobacter nodosus, are associated with hoof thrush in horses. Fourteen hoof samples, collected from eight horses with thrush and 14 samples collected from eight horses with healthy hooves, were examined for the presence of F. necrophorum, Fusobacterium equinum and D. nodosus. Only isolates with phenotypic characteristics representing Fusobacterium could be cultured. Total DNA extracted from the 28 hoof samples was amplified by using DNA primers designed from gene lktA, present in F. necrophorum su...
Malone E, Graham L.Choice of an analgesic for gastrointestinal pain requires consideration of the cause of the pain, desired duration of pain relief, need for sedation, and potential side effects and toxicity, particularly in light of other drugs being used and effects on the gastrointestinal tract. It is imperative that close monitoring be continued to ensure that surgical lesions or worsening conditions are detected. Recent research in the field may lead to new drugs, drug combinations, and avenues of treatment that minimize the side effects of these drugs while maximizing their efficacy.
Dunkel B, Rickards KJ, Page CP, Cunningham FM.Platelet activation occurs in human obstructive airway diseases and in laboratory animal models. However, there is limited evidence that platelets may be involved in equine recurrent airway obstruction (RAO) and other inflammatory diseases. This study investigated whether platelet activation also occurred in RAO. Objective: Platelet function is altered in ponies with active RAO. This alteration can be detected ex vivo by measuring platelet adhesion. Methods: An in vitro platelet adhesion assay measuring acid phosphatase (AcP) activity colorimetrically was adapted for use with equine platelets ...
Dzierzecka M, Charuta A.The bone mineral density (BMD) and the bone mineral content (BMC) in the bone tissue of the bilateral first phalanges of horses' thoracic limbs were analysed. The research material consisted of isolated pastern bones derived from 22 horses. The research was conducted with the use of a Norland model Excell Plus densitometer (Fort Atkinson WI, USA), using affinited beam X-ray technology and an animal research programme (Research Scan, 3.9.6. version) at the following parameters: scanning resolution of 1.5 x 1.5 mm, scanning speed 60 mm/s. The differences between BMC and BMD values in bilateral f...
Mespoulhès-Rivière C, Brandenberger O, Rossignol F, Robert C, Perkins JD, Marie JP, Ducharme N.OBJECTIVE To develop and assess the feasibility, repeatability, and safety of an ultrasound-guided technique to stimulate the first cervical nerve (FCN) at the level of the alar foramen of the atlas of horses. ANIMALS 4 equine cadavers and 6 clinically normal Standardbreds. PROCEDURES In each cadaver, the FCN pathway was determined by dissection, and any anastomosis between the first and second cervical nerves was identified. Subsequently, each of 6 live horses underwent a bilateral ultrasound-guided stimulation of the FCN at the alar foramen 3 times at 3-week intervals. After each procedure, ...
Bailly-Chouriberry L, Cormant F, Garcia P, Kind A, Popot MA, Bonnaire Y.Cobra venom (Naja kaouthia) contains a toxin called α-cobratoxin (α-Cbtx). This toxin is a natural protein containing 71 amino acids (MW 7821 Da) with a reported analgesic potency greater than morphine. In 2007, in USA, this substance was found in the barns of a thoroughbred trainer and since then till date, the lack of a detection of this molecule has remained a recurring problem for the horseracing industry worldwide. To solve this problem, the first method for the detection of α-cobratoxin in equine plasma has now been developed. Plasma sample (3 mL) was treated with ammonium sulfate at ...
Fricker C, Riek W, Hugelshofer J.The digital arteries of 10 horses suffering from navicular disease, and 7 horses from a control group, were examined angiographically. The horses from the disease group showed complete or partial occlusion of the digital arteries in all cases. In the control group of 7 healthy horses, isolated vessel obstructions were also found but these were limited to narrowing of part of an artery only. Histological investigations showed that total occlusion of a vessel involved an organised thrombus but that partial occlusion generally involved changes to the vascular wall, similar to those caused by enda...
DiPietro JA, Todd KS, Lock TF, Reuter-Dallman V.Fifty horses from a herd known to have benzimidazole-resistant small strongyles were treated with febantel (6 mg/kg), combinations of febantel (6 mg/kg) and piperazine citrate (25 or 55 mg base/kg), thiabendazole (44 mg/kg), or placebo (0.6 ml of water/kg). Pretreatment and 7-day posttreatment fecal examinations were done. Fecal cultures, strongyle egg per gram (epg) counts, sugar flotation fecal examinations, and in vitro testing for benzimidazole resistance were performed. Results of fecal examinations before treatment were similar in all horses, and results of testing were positive for benz...
Štritof Z, Mitchell C, Turk N, Habuš J, Hađina S, Perharić M, Waller AS.Clinical cases resembling strangles are regularly seen in some areas of Croatia. However, there are no data on the prevalence of infection and the clinical forms or geographic distribution of the disease. The aim of this study was to determine the seroprevalence of Streptococcus equi subspecies equi in horses resident in Croatia, in order to estimate the geographic distribution of infection. The study included 291 horse sera from the eight counties where the majority of Croatian horses are kept. Sera were tested by indirect ELISA (iELISA) for the presence of serum antibodies against S. equi pr...
Roser JF, Hughes JP.Five fertile and five subfertile stallions were treated with a single intravenous injection of saline the first week followed by a single intravenous injection of varying doses of gonadotropin-releasing hormone (5, 10, 25, 100, 500 micrograms) given in a randomized fashion over the next 5 weeks during the nonbreeding season. Blood samples were collected periodically before and after treatment for analysis of luteinizing hormone, follicle stimulating hormone, and testosterone content by radioimmunoassay. Before treatment, semen samples were collected every other day for 3 weeks for analysis of ...
Hackett RP, Ducharme NG, Ainsworth DM, Erickson BK, Erb HN, Soderholm LV, Thorson LM.To determine whether dorsal displacement of the soft palate (DDSP) results in pulmonary artery hypertension and leads to increases in transmural pulmonary artery pressure (TPAP); to determine whether pulmonary hypertension can be prevented by prior administration of furosemide; and to determine whether tracheostomy reduces pulmonary hypertension. Methods: 7 healthy horses. Methods: Horses were subjected to 3 conditions (control conditions, conditions after induction of DDSP, and conditions after tracheostomy). Horses were evaluated during exercise after being given saline (0.9% NaCl) solution ...
