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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Significance for exercise capacity of some electrocardiographic findings in racehorses.
Australian veterinary journal    July 1, 1994   Volume 71, Issue 7 200-202 doi: 10.1111/j.1751-0813.1994.tb03401.x
King CM, Evans DL, Rose RJ.Various cardiorespiratory and metabolic indices were assessed during treadmill exercise in Thoroughbred and Standardbred racehorses with T wave changes in 4 or more leads on the electrocardiogram or second-degree atrio-ventricular (AV) block, and in horses that had no abnormalities on clinical examination, resting electrocardiography or upper respiratory tract endoscopy. No significant differences in heart rate, plasma lactate concentration, arterial blood gases, oxygen uptake, run time, peak velocity, or blood and red cell volumes were found between normal horses and horses with T wave change...
Clinical efficacy and safety of clenbuterol HCl when administered to effect in horses with chronic obstructive pulmonary disease (COPD).
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 331-336 doi: 10.1111/j.2042-3306.1994.tb04396.x
Erichsen DF, Aviad AD, Schultz RH, Kennedy TJ.A field study of 239 horses was conducted to determine the efficacy and safety of clenbuterol HCl, a beta 2-adrenergic bronchodilator, when administered incrementally to effect in the treatment of chronic obstructive pulmonary disease (COPD). The severity of COPD (heaves) and response to treatment was determined by clinical evaluation; an overall 'heaveiness rating' (OHR) was assigned at each observation. The horses were treated orally b.i.d. with clenbuterol (as Ventipulmin Syrup), beginning with the lowest dosage of 0.8 micrograms/kg. On day 10 of treatment at the effective dose (0.8, 1.6, 2...
Technique for long-term ileal cannulation in ponies. Peloso JG, Schumacher J, McClure SR, Crabill MR, Hanselka DV, Householder DD, Potter GD.A T-cannula was fitted permanently into the ileum of ten mature ponies to quantify the role of the prececal and postileal segments of the digestive tract in equine nutrition studies. The ponies were anesthetized, positioned in left lateral recumbency, and the distal small intestine was exteriorized through a right paralumbar incision. A silastic T-cannula was inserted through a 2-cm longitudinal incision into the lumen of the ileum, on the antimesenteric surface, and sutured to the ileum. The stem of the cannula was exteriorized through a 2-cm circular skin incision, 6 cm caudal to the 16th ri...
Effect of helium-induced ventilatory unloading on breathing and diaphragm EMG in awake ponies.
Journal of applied physiology (Bethesda, Md. : 1985)    July 1, 1994   Volume 77, Issue 1 452-462 doi: 10.1152/jappl.1994.77.1.452
Forster HV, Erickson BK, Lowry TF, Pan LG, Korducki MJ, Forster AL.Two questions were addressed in this study: 1) Does respiratory resistive unloading (inspired O2 fraction = 0.21, inspired He fraction = 0.79) elicit a compensatory reduction in stimulation of the diaphragm? 2) Do diaphragm and lung afferents contribute to compensatory responses to unloading? Ten intact (I), five diaphragm-deafferented (DD), four hilar nerve-denervated (HND), and seven DD+HND adult ponies were studied at rest and during mild and moderate treadmill exercise. During steady-state unloading at rest, duration of the diaphragm electromyogram (EMGdi) was less (P < 0.05) than contr...
In vitro mechanical properties and failure mode of the equine (pony) cranial cruciate ligament.
Veterinary surgery : VS    July 1, 1994   Volume 23, Issue 4 257-265 doi: 10.1111/j.1532-950x.1994.tb00480.x
Rich FR, Glisson RR.In vitro failure modes and mechanical properties of the equine cranial cruciate ligament (CCL) were evaluated in 15 stifle joints from 10 ponies. Ponies were from 3 to 25 years of age and weighed from 122 to 208 kg. Femur-CCL-tibia specimens were mounted in 48 degrees of flexion, distracted until a 500-g tensile preload was achieved, and then tested by tensile loading to failure. Specimens failed by complete midsubstance CCL rupture (n = 9), combined tibial insertion avulsion fracture and midsubstance CCL rupture (n = 4), and combined femoral origin avulsion fracture and midsubstance CCL ruptu...
[Horse with afterbirth].
Tijdschrift voor diergeneeskunde    July 1, 1994   Volume 119, Issue 13 405-406 
de Kruif A.No abstract available
Arthroscopic removal of osteochondral fragments from the proximal interphalangeal joint of the pelvic limbs in three horses.
Journal of the American Veterinary Medical Association    July 1, 1994   Volume 205, Issue 1 79-82 
Schneider RK, Ragle CA, Carter BG, Davis WE.Osteochondral fragments detected in the proximal interphalangeal joint in the pelvic limbs of 3 horses (2 Standardbreds and 1 Thoroughbred) caused joint enlargement and lameness. Fragments were removed by use of arthroscopy. Accurate placement of the arthroscope into the dorsal joint space was necessary to obtain an adequate view of the fragments. After surgery, 2 of the horses resumed racing without joint problems, and the third was in training to race. High-detail radiographs are necessary to detect osteochondral fragments in horses with joint enlargement or lameness localized to the proxima...
Effects of training on blood lactate-running speed relationship in thoroughbred racehorses.
Journal of applied physiology (Bethesda, Md. : 1985)    July 1, 1994   Volume 77, Issue 1 298-302 doi: 10.1152/jappl.1994.77.1.298
Von Wittke P, Lindner A, Deegen E, Sommer H.In this study the effects of training history on the results of a standardized two-speed test in competing Thoroughbreds were investigated during a racing season. For nine Thoroughbreds, 1,755 training days were recorded. Within the observation period each horse completed a two-speed field test at intervals of 6-8 wk to determine its running velocity (v) eliciting blood lactate concentrations of 4 (v4) and 12 mmol/l (v12). Horses performed 29 two-speed tests. Changes of v4 and v12 in a horse between two consecutive tests were used to assess effects of training history variables calculated for ...
Bilateral tibial metaphyseal stress fractures associated with physitis in a foal.
Journal of the American Veterinary Medical Association    July 1, 1994   Volume 205, Issue 1 76-78 
Frankeny RL, Johnson PJ, Messer NT, Keegan KG, Corwin LA.A 7-month-old Appaloosa foal had bilateral hind limb lameness and was unable to rise from recumbency without assistance. Lameness could be exacerbated by tarsal flexion and a firm swelling at the distomedial aspect of the tibias was associated with a marked pain response when palpated. Radiography revealed enlargement of the distal tibial metaphysis physis (compared with normal), and radiolucent fissure lines extending proximally from the physis into the metaphysis at its medial aspect. Treatment included rest and dietary adjustment. Although clinical signs initially resolved following treatme...
Anecdotes and clinical trials: the story of clenbuterol.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 256-258 doi: 10.1111/j.2042-3306.1994.tb04384.x
Derksen FJ.No abstract available
Initial characterization of equine inhibin.
Biology of reproduction    July 1, 1994   Volume 51, Issue 1 63-71 doi: 10.1095/biolreprod51.1.63
Moore KH, Dunbar BS, Bousfield GR, Ward DN.Inhibin has been characterized from a number of mammals; however, it has not been extensively studied in horses. Western blot analysis was used to examine the size heterogeneity of equine inhibin alpha- and beta-subunits. The distribution of equine inhibin activity from the initial sizing column (S-200, 25 x 94 cm) indicated that the majority of equine inhibin activity was present as larger-molecular-size forms. When the large forms were analyzed by Western blot in nonreducing conditions, alpha-subunit bands were detected at 40,000 M(r), 56,000 M(r), 80,000 M(r), and 90,000 M(r); beta a reacti...
Differential scanning calorimetric studies of superficial digital flexor tendon degeneration in the horse.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 291-296 doi: 10.1111/j.2042-3306.1994.tb04389.x
Miles CA, Wardale RJ, Birch HL, Bailey AJ.Differential scanning calorimetry (DSC) of equine superficial digital flexor tendons revealed the presence of a small exothermic peak at 23 degrees C of unknown origin, and a large endothermic peak at 70 degrees C due to denaturation of cross-linked collagen fibres. In the central degenerated core of damaged tendons the denaturation temperature remained at 70 degrees C but the enthalpy decreased in relation to the extent of degeneration of the tendon. We suggest that this reduction in enthalpy is due to depolymerisation and denaturation of the collagen fibres. This contention is supported by t...
Joint structure, biochemistry and biochemical disequilibrium in synovitis and equine joint disease.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 263-277 doi: 10.1111/j.2042-3306.1994.tb04386.x
Palmer JL, Bertone AL.No abstract available
Variation in the concentration of long chain free fatty acids in equine plasma over 24 hours.
The British veterinary journal    July 1, 1994   Volume 150, Issue 4 339-347 doi: 10.1016/s0007-1935(05)80150-2
Orme CE, Dunnett M, Harris RC.The primary aim of this study was to examine the within-day variation in the concentration of total and individual long chain free fatty acids (C > 14) in normally fed horses. Plasma samples were collected over a 24 h period from 12 resting horses during three separate sessions (six horses in the first session and three in the second and third). Samples were analysed for individual long chain free fatty acids (FFA) and glucose. During normal feeding, the predominant FFA in plasma were palmitic (C16:0), linoleic (C18:2), oleic (C18:1), stearic (C18:0) and linolenic (C18:3). Together these ac...
Platelet-poor plasma not suitable for clinical endotoxin testing, demonstrated in horses.
Clinical chemistry    July 1, 1994   Volume 40, Issue 7 Pt 1 1346-1347 
Steverink JG, Sturk A, Salden HJ.No abstract available
The structure, innervation and location of arteriovenous anastomoses in the equine foot.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 305-312 doi: 10.1111/j.2042-3306.1994.tb04391.x
Molyneux GS, Haller CJ, Mogg K, Pollitt CC.In the foot of the horse, arteriovenous anastomoses (AVAs) of epithelioid type occurred in the dermis of the coronary band, in the coronary and terminal papillae, in neurovascular bundles and at the entrance to and along the length of the dermal laminae. A particular feature of the epithelioid segment of AVAs in the horse, compared with that of other species, was the height and surface complexity of many of the endothelial cells. They extended into the lumen, forming undercut and tunnel-like areas which correlated with the characteristic surface marking of AVAs observed in vascular casts. The ...
Effects of polymyxin B and Salmonella typhimurium antiserum on horses given endotoxin intravenously.
American journal of veterinary research    July 1, 1994   Volume 55, Issue 7 921-927 
Durando MM, MacKay RJ, Linda S, Skelley LA.Polymyxin B and an antiserum against an Re mutant Salmonella typhimurium were evaluated for protective effect in an equine model endotoxemia. Six 3- to 5-month-old foals were given endotoxin (0.25 micrograms/kg of body weight) IV after no pretreatment, or pretreatment with polymyxin B (6,000 U/kg, IV) or S typhimurium antiserum (1.5 ml/kg, IV). When given without pretreatment, endotoxin caused transient recumbency and increases in rectal temperature, and heart and respiratory rates. In addition, leukopenia and increases in circulating tumor necrosis factor (TNF) and interleukin 6 (IL-6) activi...
Effect of ligation on internal carotid artery blood pressure in horses.
Veterinary surgery : VS    July 1, 1994   Volume 23, Issue 4 250-256 doi: 10.1111/j.1532-950x.1994.tb00479.x
Freeman DE, Donawick WJ, Klein LV.The effect of a single ligature on back pressure in the internal carotid artery was studied in nine horses. In six anesthetized horses, one internal carotid artery was catheterized 2 cm from its origin and blood pressure was recorded continuously. Then the artery was ligated, pressure was recorded again, and the horses were euthanatized. In another three anesthetized horses, indwelling catheters were placed in both internal carotid arteries and a loose ligature was placed proximal to one catheter. After horses recovered from anesthesia, the ligature was tied and blood pressure was recorded in ...
An investigation of the proteoglycan metabolism of mature equine articular cartilage and its regulation by interleukin-1.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 297-303 doi: 10.1111/j.2042-3306.1994.tb04390.x
Platt D, Bayliss MT.The effect of human recombinant interleukin-1 beta (rhIL-1 beta) on proteoglycan metabolism was investigated in cultures of full thickness explants of articular cartilage from horses 3-21 years of age. Proteoglycan synthesis was inhibited at all ages but no alteration in the hydrodynamic size or electrophoretic heterogeneity was observed in proteoglycan isolated from rhIL-1 beta stimulated cartilage. The sulphation pattern of the newly synthesised proteoglycan molecules was, however, significantly affected by the presence of the peptide regulatory factor. Interleukin-1 had no effect on the rat...
The Equine Virology Research Foundation–a view from abroad.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 259-262 doi: 10.1111/j.2042-3306.1994.tb04385.x
Allen GP.No abstract available
An equine B cell surface antigen defined by a monoclonal antibody.
Veterinary immunology and immunopathology    July 1, 1994   Volume 42, Issue 1 91-102 doi: 10.1016/0165-2427(94)90092-2
Zhang CH, Donaldson WL, Antczak DF.A surface antigen of equine B lymphocytes was identified using the Equine Leucocyte Antigen Workshop antibody WS 65. This marker was expressed on almost all equine B cells, but not on T cells, granulocytes or thymocytes. WS 65 strongly stained cells in the follicular areas of lymph nodes and cells in the splenic nodules when tested on frozen tissue sections by immunohistochemistry. Equine leukemic T cells were not labeled by WS 65, and neither were the cells from a horse with B cell leukemia, although these latter cells carried surface immunoglobulin. Immunoprecipitation of lymphocyte membrane...
Morphological effects of arthroscopic partial synovectomy in horses.
Veterinary surgery : VS    July 1, 1994   Volume 23, Issue 4 231-240 doi: 10.1111/j.1532-950x.1994.tb00477.x
Jones DL, Barber SM, Jack SW, Doige CE.Gross and microscopic effects of arthroscopic partial synovectomy on synovium and articular cartilage of middle carpal joints were studied in 15 horses. A 7-mm diameter motorized synovial resector was inserted into each middle carpal joint and arthroscopic partial synovectomy and lavage or arthroscopic lavage alone was performed. Study periods were 0 (three horses), 16 (three horses), and 30 days (six horses). No gross evidence of degenerative joint disease was observed at day 16 or 30. At 30 days, resected areas lacked villi and there was deposition of fibrin on the synovial surface with vary...
Comparison of measured and calculated values for colloid osmotic pressure in hospitalized animals.
American journal of veterinary research    July 1, 1994   Volume 55, Issue 7 910-915 
Brown SA, Dusza K, Boehmer J.A relation exists between colloid osmotic pressure (pi) and serum total protein concentration; equations describing this relation have been used to determine a calculated value for pi. However, the relation between total protein concentration and pi is altered by the method used to measure protein and by changes in the ratio of concentrations of albumin (A) to globulin (G). We developed nomograms for estimating pi from A and G concentrations, using samples obtained from clinically normal animals and compared the accuracy of these nomograms with that of previously described equations relating p...
Diagnostic ophthalmology.
The Canadian veterinary journal = La revue veterinaire canadienne    July 1, 1994   Volume 35, Issue 7 450-452 
Wolfer J, Grahn B.No abstract available
An examination of the occurrence of surgical wound infection following equine orthopaedic surgery (1981-1990).
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 323-326 doi: 10.1111/j.2042-3306.1994.tb04394.x
MacDonald DG, Morley PS, Bailey JV, Barber SM, Fretz PB.Post operative surgical wound infection rates were determined 452 cases of equine orthopaedic surgery performed at the Western College of Veterinary Medicine, Saskatoon, Saskatchewan, between January 1, 1981 and December 31, 1990. Only surgical procedures classified as clean or clean-contaminated by the National Research Council were included in this study. The overall post operative infection rate was 10.0% (45 of 452). Clean surgeries (n = 433) had an 8.1% infection rate while clean-contaminated surgeries (n = 19) had a 52.6% infection rate. Information collected from the medical records was...
Hemolytic complement activity and concentrations of its third component during maturation of the immune response in colostrum-deprived foals.
American journal of veterinary research    July 1, 1994   Volume 55, Issue 7 928-933 
Bernoco MM, Liu IK, Willits NH.Six foals were deprived of colostrum for the first 36 hours after birth and, instead, received reconstituted powdered milk. Five control foals suckled their dams naturally. Blood samples were obtained from all the foals after birth and at approximately weekly intervals until at least 5.5 months of age. Sera were analyzed for hemolytic complement activity, complement component C3, and correlating IgG concentration. Hemolytic complement (P = 0.0145) and C3 (P = 0.0002) values were significantly higher in colostrum-deprived foals (CDF) than in naturally nursed foals at 2 to 5 days of age. In addi...
Measurement by ELISA of equine alpha-1-proteinase inhibitor in uterine flushings from mares.
Research in veterinary science    July 1, 1994   Volume 57, Issue 1 45-52 doi: 10.1016/0034-5288(94)90080-9
Scudamore CL, Pemberton AD, Miller HR, McDonnell AM, Thomson SR, Dawson A, Watson ED.An enzyme linked immunosorbent assay (ELISA) was developed and used to estimate the concentrations of the serine proteinase inhibitor, alpha-1 proteinase inhibitor (API), in uterine flushings recovered from mares at different stages of the oestrous cycle and before and after the induction of experimental endometritis. There was a significant increase in the concentrations of API and albumin relative to total protein in flushings recovered during oestrus compared with dioestrus but no difference was observed in the concentrations of these proteins relative to total protein before and after the ...
Comparative effects of mu and kappa opiate agonists on the cecocolic motility in the pony. Roger T, Bardon T, Ruckebusch Y.The electrical and mechanical activity of the large intestine and its response to administration of opiate mu and kappa agonists were assessed from electrodes and inductograph coils chronically implanted on the cecocolic segment in six ponies given a diet of hay and concentrates. Before the drugs were given, migrating complexes propagating from the cecum into the colon occurred at the rate of 1.5 to 16/hour. During this propulsive activity, the cecocolic sphincter opened and closed allowing the outflow of cecal contents and preventing the backflow of colic contents. Each pony was used as its o...
Horse products for tetanus prophylaxis. Shindman J.No abstract available
Outbreak of equine influenza in polo horses in Ibadan, Nigeria: virus isolation, clinical manifestation and diagnosis.
The Veterinary record    June 25, 1994   Volume 134, Issue 26 683-684 doi: 10.1136/vr.134.26.683
Adeyefa CA, McCauley JW.No abstract available