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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Natural killer cells in normal horses and specific-pathogen-free foals infected with equine herpesvirus.
Veterinary immunology and immunopathology    June 1, 1992   Volume 33, Issue 1-2 103-113 doi: 10.1016/0165-2427(92)90038-r
Chong YC, Duffus WP, Hannant D.Peripheral blood mononuclear cells (PBMC) from an adult horse and from foals demonstrated natural killer (NK)-type cytotoxicity against a range of xenogeneic and allogeneic cell targets. The human tumour cell line, Chang liver was consistently the most susceptible. Chang liver, rabbit kidney (RK-13), equine sarcoid (ES) and embryonic equine kidney (EEK) cells were more susceptible when presented to horse PBMC than monolayer cultures. Embryonic equine lung (EEL) and murine YAC-1 cells conversely, were more susceptible in a trypsinized state. Horse PBMC demonstrated higher levels of NK-type acti...
Microvascular circulation of the small intestine in horses.
American journal of veterinary research    June 1, 1992   Volume 53, Issue 6 995-1000 
Dart AJ, Snyder JR, Julian D, Hinds DM.The microvascular anatomic features of the small intestine was described by correlating results of microangiography, light microscopy, gross studies, and scanning electron microscopy of vascular replicas in 14 horses. After heparinization, the horses were euthanatized, a length of jejunum was transected, and blood was flushed free of the circulation, using isotonic NaCl solution. In six horses, the circulatory system was perfused with a modified radiopaque medium and evaluated radiographically. These sections were then evaluated by standard histologic methods. Sections from 8 horses were perfu...
Diversity of the antibody responses produced in ponies and mice against the equine influenza A virus H7 haemagglutinin.
The Journal of general virology    June 1, 1992   Volume 73 ( Pt 6) 1569-1573 doi: 10.1099/0022-1317-73-6-1569
Appleton JA, Gagliardo LF.A large panel of mouse monoclonal antibodies was produced and tested against field isolates of the equine H7N7 influenza A virus subtype. Only a limited degree of H7 haemagglutinin variation was detected. At least four antigenic sites were identified by selecting variant viruses in eggs. The limited variation in the field did not correlate with the frequency of variant viruses detected in eggs; this frequency was similar to those reported for other influenza viruses. We sought to determine whether the limited amount of variation could be correlated with an epitope-restricted antibody response ...
Arthroscopic removal of an osteochondral fragment from the caudal pouch of the lateral femorotibial joint in a colt.
Journal of the American Veterinary Medical Association    June 1, 1992   Volume 200, Issue 11 1695-1697 
Stick JA, Borg LA, Nickels FA, Peloso JG, Perau DL.An osteochondral fragment was removed from the caudal pouch of the lateral femorotibial joint in a 2-year-old Trakehner colt by use of arthroscopic surgery and a lateral approach. The approach to this aspect of the femorotibial joints was developed in another horse. The fragment was not attached and resembled an osteochondritis dissecans lesion. The intermittent lameness associated with the fragment resolved after surgical removal. A positive response to diagnostic anesthesia of the femorotibial joint in the absence of a confirmed diagnosis (following radiographic and arthroscopic evaluations ...
The effect of regional nerve blocks on the lameness caused by collagenase induced tendonitis in the midmetacarpal region of the horse: a study using gait analysis, and ultrasonography to determine tendon healing.
Zentralblatt fur Veterinarmedizin. Reihe A    June 1, 1992   Volume 39, Issue 5 349-364 doi: 10.1111/j.1439-0442.1992.tb00192.x
Keg PR, van den Belt AJ, Merkens HW, Barneveld A, Dik KJ.The influence of regional nerve blocks on lameness resulting from tendon injury was studied in six horses. Tendonitis was induced in the midmetacarpal region of the Superficial Digital Flexor Tendon (SDF), Deep Digital Flexor Tendon (DDF) and the Suspensory Ligament (SL) through collagenase injections. The results were evaluated through sequential clinical examinations, ultrasonographic imaging and kinetic gait analysis (force plate) during a period of 144 days post injury and subsequently compared with gross and microscopic findings. The lameness corresponding to the SDF and DDF tendon lesion...
Steroid hepatopathy in a horse with glucocorticoid-induced hyperadrenocorticism.
Journal of the American Veterinary Medical Association    June 1, 1992   Volume 200, Issue 11 1682-1684 
Cohen ND, Carter GK.Steroid hepatopathy was diagnosed in a horse with glucorticoid-induced hyperadrenocorticism on the basis of anamnesis, serum biochemical data, and histologic findings of hepatic biopsy. Initially, clinical signs of polyuria, polydypsia, and muscular degeneration were seen. The horse developed laminitis during hospitalization.
Cryptococcosis in seven horses.
Australian veterinary journal    June 1, 1992   Volume 69, Issue 6 135-139 doi: 10.1111/j.1751-0813.1992.tb07482.x
Riley CB, Bolton JR, Mills JN, Thomas JB.The clinical, radiographic and post-mortem findings in 6 horses with cryptococcal pneumonia and one horse with an abdominal cryptococcal granuloma are described. In pulmonary cryptococcosis, the lesions were either diffuse and multiple, with bilateral lung involvement, or localised mainly to the dorsocaudal region of one lung. The cases of diffuse multiple cryptococcosis were thought to be associated with haematogenous spread of the fungus after gastrointestinal infection and dissemination from regional lymph nodes. The localised form of the disease was thought to have been associated with inh...
Septic metritis secondary to torsion of a pedunculated uterine fibroleiomyoma in a filly.
Journal of the American Veterinary Medical Association    June 1, 1992   Volume 200, Issue 11 1685-1688 
Broome TA, Allen D, Baxter GM, Pugh DG, Mahaffey E.A 2-year-old Arabian filly was referred for evaluation of a serosanguineous vaginal discharge. Palpation per rectum revealed a large, fluid-filled uterus and a uterine mass. The filly developed septic metritis and secondary laminitis as a result of torsion and necrosis of a pedunculated uterine mass. Ovariohysterectomy was performed. The entire cervix was removed with the uterus. Gross examination of the excised uterus revealed 3 intraluminal masses. Histologic evaluation identified the tumors as fibroleiomyoma. The filly recovered completely, and there was no recurrence of the tumor.
Putative equine protozoal myeloencephalitis in an imported Arabian filly.
Journal of the South African Veterinary Association    June 1, 1992   Volume 63, Issue 2 78-79 
Ronen N.No abstract available
Immunocytochemical study of the diffuse neuroendocrine system cells in equine lungs.
Anatomia, histologia, embryologia    June 1, 1992   Volume 21, Issue 2 136-145 doi: 10.1111/j.1439-0264.1992.tb00330.x
Rodríguez A, Peña L, Flores JM, González M, Castaño M.This study was undertaken to investigate the presence of neuroendocrine cells (N.E.C.) by immunocytochemical means in equine lungs during three distinct evolutionary periods: fetal, neonatal and adult. The authors identified bombesin, somatostatin and calcitonin secretory cells. In the fetal lungs the N.E.C. were located in the interstitial tissue and exhibited greater immunoreactivity to bombesin than to the other two neuropeptides studied. A large number of calcitonin-producing cells and a smaller number of bombesin-positive cells were seen in the bronchial and bronchiolar epithelium of newb...
Rifampin disposition in the horse: effects of age and method of oral administration.
Journal of veterinary pharmacology and therapeutics    June 1, 1992   Volume 15, Issue 2 124-132 doi: 10.1111/j.1365-2885.1992.tb00999.x
Burrows GE, MacAllister CG, Ewing P, Stair E, Tripp PW.The effects of time and method of administration of rifampin with respect to feeding were evaluated in five mature horses. There was a significant (P less than or equal to 0.05) delay in time of maximum serum concentration and an apparent but not significant decrease in oral absorption when rifampin was given as a top dressing on grain as compared with administration in corn syrup 2 h before or 2 h after feeding. Although there were no differences between administration before or after feeding, administration 2 h prior to feeding was selected as the method of choice for future experiments. The...
Mycotoxicosis associated with Penicillium purpurogenum in horses in Nigeria.
The Veterinary record    May 30, 1992   Volume 130, Issue 22 495 doi: 10.1136/vr.130.22.495
Ocholi RA, Chima JC, Chukwu CO, Irokanulo E.No abstract available
Metastatic granulosa cell tumor in a mare.
Journal of the American Veterinary Medical Association    May 15, 1992   Volume 200, Issue 10 1525-1526 
Gift LJ, Gaughan EM, Schoning P.A 5-year-old Quarter Horse mare was referred for evaluation of an acute non-weightbearing lameness of the left hind limb in which musculoskeletal abnormalities had not been detected. After admission, the mare had signs of colic. Exploratory laparotomy revealed the left ovary to be large, masses in the left sublumbar space, and diffuse infiltration of the mesentery, omentum, liver, and spleen with variably-sized masses. The mare was euthanatized, and granulosa cell tumor was identified on histologic examination of the left ovary, left sublumbar and cranial thoracic lymph nodes, omentum, mesente...
Diagnosis of ruptured urinary bladder in a foal by the identification of calcium carbonate crystals in the peritoneal fluid.
Journal of the American Veterinary Medical Association    May 15, 1992   Volume 200, Issue 10 1515-1517 
Morley PS, Desnoyers M.A 3-day-old Quarter Horse colt was examined because of signs of severe depression, discomfort, and abdominal straining. The foal seemed disoriented, and the abdomen was tense and distended ventrally. The differential diagnoses included ruptured urinary bladder, retained meconium, septicemia/bacteremia, and neonatal maladjustment syndrome. Serum biochemical analysis revealed marked hyponatremia, hypochloremia, and moderate hyperkalemia, as well as mildly high urea, creatinine, and phosphorus concentrations. The primary differential diagnosis at this time was ruptured urinary bladder. Abdominoce...
Eosinophilic gastroenteritis with encapsulated nematodes in a horse.
Journal of the American Veterinary Medical Association    May 15, 1992   Volume 200, Issue 10 1518-1520 
Cohen ND, Loy JK, Lay JC, Craig TM, McMullan WC.A 3-year-old Quarter Horse gelding admitted for evaluation of weight loss, signs of depression, and dermatitis of the coronary bands was found to have eosinophilic gastroenteritis. Intralesional nematodes identified as Strongylus edentatus were seen in multiple microscopic sections of the small colon, suggesting a parasitic cause of the disease.
Septic cholangitis and peritonitis in a gelding.
Journal of the American Veterinary Medical Association    May 15, 1992   Volume 200, Issue 10 1521-1524 
Clabough DL, Duckett W.An 8-year-old Arabian gelding with septic cholangitis and peritonitis was successfully treated with trimethoprim/sulfadiazine. The gelding was referred for evaluation of signs of abdominal pain, icterus, fever, and weight loss. Peritoneal fluid analysis revealed septic and suppurative peritonitis. Culture of the peritoneal fluid yielded Escherichia coli and Klebsiella pneumoniae, which were sensitive to trimethoprim/sulfadiazine. On the basis of results of hepatic ultrasonography, a diagnosis of septic cholangitis also was made. The horse was treated with 30 mg of trimethoprim/sulfadiazine/kg,...
Chlamydia psittaci infection in horses: results of a prevalence survey and experimental challenge.
The Veterinary record    May 9, 1992   Volume 130, Issue 19 417-419 doi: 10.1136/vr.130.19.417
Mair TS, Wills JM.Nasal and conjunctival swabs were obtained from 300 horses and Chlamydia psittaci was isolated from 15 of them (5 per cent). Eleven nasal swabs and six conjunctival swabs were positive on culture, but there was no association between the isolation of the organism and the presence of clinical ocular or respiratory disease. Six ponies were challenged with an equine isolate of C psittaci into the eye, nasal cavity or bronchial tree. The organism could be isolated from nasal and conjunctival swabs taken from the ponies for up to 17 days after challenge, but there was no clinical evidence of diseas...
Bone scanning for back problems in horses.
The Veterinary record    May 9, 1992   Volume 130, Issue 19 432 doi: 10.1136/vr.130.19.432-b
Jeffcott LB, Weaver MP.No abstract available
Small colon intussusception associated with an intralumenal leiomyoma in a pony.
The Veterinary record    May 2, 1992   Volume 130, Issue 18 403-404 doi: 10.1136/vr.130.18.403
Mair TS, Davies EV, Lucke VM.No abstract available
Multisystemic eosinophilic epitheliotropic disease in a horse: attempted treatment with hydroxyurea and dexamethasone.
The Veterinary record    May 2, 1992   Volume 130, Issue 18 392-395 doi: 10.1136/vr.130.18.392
Hillyer MH, Mair TS.Equine multisystemic eosinophilic epitheliotropic disease is rare in horses. The clinical signs vary according to the organs affected, the skin and gastrointestinal tract being most commonly involved. This paper gives the first reported description of a horse with multisystemic eosinophilic epitheliotropic disease in the United Kingdom and the attempts to treat it. The horse showed dermatological, gastrointestinal, hepatic, pulmonary and pancreatic involvement. Some improvement was seen when the horse was treated with corticosteroid and hydroxyurea.
Comparison of endometrium before and after repair of third-degree rectovestibular lacerations in mares.
Journal of the American Veterinary Medical Association    May 1, 1992   Volume 200, Issue 9 1336-1338 
Schumacher J, Schumacher J, Blanchard T.The endometrial response of mares to repair of third-degree rectovestibular lacerations was evaluated. Endometrial biopsy specimens from 8 mares with third-degree rectovestibular laceration were obtained immediately before surgery and from 9 to 15 days after repair. Presurgical endometrial biopsy specimens were classified as category I for 2 mares; category II, attributable to slight endometritis, for 5 mares; and category III, attributable to moderate-to-severe endometritis, for 1 mare. Within 15 days after rectovestibular repair, all endometrial biopsy specimens were classified as category I...
Pharmacologic evaluation of factor XIIIa*-like enzyme activity in equine plasma as a potential therapeutic avenue for the inhibition of fibrinous tissue.
American journal of veterinary research    May 1, 1992   Volume 53, Issue 5 695-705 
Coyne CP, Smith JE, DeBowes RM.Several pharmaceutical compounds were evaluated for their ability to selectively inhibit activated coagulation factor-XIII-like enzyme activity (eg, XIIIa*) in pooled equine plasma. Presence of coagulation factor-XIIIa*-like enzyme activity in plasma was established by assay procedures involving incorporation of the fluorescent amine compound, monodansylcadaverine, into purified casein, which served as a protein substrate. Pharmaceuticals inhibitory to coagulation factor-XIIIa*-like enzyme activity were recognized by plasma gel formation of high spectrophotometric transmittance (transparency),...
Failure of passive transfer in foals.
Journal of veterinary internal medicine    May 1, 1992   Volume 6, Issue 3 197-198 doi: 10.1111/j.1939-1676.1992.tb00337.x
Baldwin JL.No abstract available
Loss of absorptive capacity for sodium and chloride in the colon causes diarrhoea in Potomac horse fever.
Research in veterinary science    May 1, 1992   Volume 52, Issue 3 353-362 doi: 10.1016/0034-5288(92)90037-3
Rikihisa Y, Johnson GC, Wang YZ, Reed SM, Fertel R, Cooke HJ.Ehrlichia risticii, an obligate intracellular bacterium in the family Rickettsiaceae, causes Potomac horse fever which is often associated with severe watery diarrhoea. The mechanism of the diarrhoea is unknown. The aim of this study was to determine whether sodium and chloride transport, morphology and cyclic adenosine 3', 5'-monophosphate (cyclic AMP) content of colonic mucosa was altered in E risticii-infected horses. Mucosa-submucosa sheets from the large and small colon of nine infected and seven to nine uninfected horses were set up in Ussing chambers for measurement of short-circuit cur...
Arrhythmias in newborn thoroughbred foals.
Equine veterinary journal    May 1, 1992   Volume 24, Issue 3 169-173 doi: 10.1111/j.2042-3306.1992.tb02809.x
Yamamoto K, Yasuda J, Too K.Foetal electrocardiograms (ECG) were obtained from 39 of 50 Thoroughbred foaling mares close to delivery. The 50 newborn foals were studied electrocardiographically during their adaptive period, immediately after birth. In 48 foals there were paroxysmal arrhythmias or mixed arrhythmias. The most common arrhythmias were sinus arrhythmias including wandering pacemaker (32/50) and atrial premature contraction (30/50). The others observed were atrial fibrillation (15/50), ventricular premature contraction (10/50), partial atrioventricular block (7/50), ventricular tachycardia (4/50), atrial tachyc...
Pulmonary artery and aortic pressure changes during high intensity treadmill exercise in the horse: effect of frusemide and phentolamine.
Equine veterinary journal    May 1, 1992   Volume 24, Issue 3 215-219 doi: 10.1111/j.2042-3306.1992.tb02818.x
Erickson BK, Erickson HH, Coffman JR.Intravenous frusemide (1.0 mg/kg bwt) or phentolamine (0.33 mg/kg bwt) was given to 7 horses 1 h before exercise and their effects on pulmonary artery and aortic pressure changes during strenuous exercise were examined. Short-term near-maximal treadmill exercise (10 m/sec, 3 degrees incline) produced increases in heart rate, mean pulmonary artery pressure (PAP), mean aortic pressure (AP), and packed cell volume (PCV). Frusemide did not affect heart rate, PAP or PCV during exercise. Frusemide significantly decreased mean AP by 10 to 15 mmHg during exercise. Phentolamine produced an increase in ...
Influence of furosemide on hemodynamic responses during exercise in horses.
American journal of veterinary research    May 1, 1992   Volume 53, Issue 5 742-747 
Olsen SC, Coyne CP, Lowe BS, Pelletier N, Raub EM, Erickson HH.Four hours prior to exercise on a high-speed treadmill, 4 dosages of furosemide (0.25, 0.50, 1.0, and 2.0 mg/kg of body weight) and a control treatment (10 ml of 0.9% NaCl) were administered IV to 6 horses. Carotid arterial pressure (CAP), pulmonary arterial pressure (PAP), and heart rate were not different in resting horses before and 4 hours after furosemide administration. Furosemide at dosage of 2 mg/kg reduced resting right atrial pressure (RAP) 4 hours after furosemide injection. During exercise, increases in treadmill speed were associated with increases in RAP, CAP, PAP, and heart rate...
Relationships of age to uterine function and reproductive efficiency in mares.
Theriogenology    May 1, 1992   Volume 37, Issue 5 1101-1115 doi: 10.1016/0093-691x(92)90108-4
Carnevale EM, Ginther OJ.The uterine function and reproductive efficiency of 31 nonlactating pony mares were compared for two age groups: young (5 to 7 years, n=9) and old (>/=15 years, n=22). For pregnant mares, differences between age groups were not significant for the diameter of the largest follicle, cross-sectional area of the corpus luteum, growth profile of the embryonic vesicle or embryo mobility characteristics. Uterine contractility scores were lower (P<0.05), day of fixation of the embryonic vesicle was later (P<0.05), and uterine tone tended (P<0.10) to be lower in the old than the young mares...
Binding of estrogen-3-sulfates to stallion plasma and equine serum albumin.
The Journal of steroid biochemistry and molecular biology    May 1, 1992   Volume 42, Issue 3-4 345-349 doi: 10.1016/0960-0760(92)90138-9
Bouhamidi R, Gaillard JL, Silberzahn P, Martin B.The binding of estrone-3-sulfate (E1-3-S) and estradiol-3-sulfate (E2-3-S) to adult stallion plasma was determined and compared with the binding to equine serum albumin (ESA). On the ESA molecule, two binding sites for E1-3-S with an association constant of 1.3 x 10(5) M-1 and several sites of weaker affinity were found; the data for E2-3-S showed the existence of four binding sites of moderate affinity (1 x 10(5) M-1) and several sites of weaker affinity. The removal of albumin from the stallion plasma resulted in the absence of binding of E1-3-S or E2-3-S, whereas the removal of glycoprotein...
Ultrasound as a tool in orthopaedics.
Equine veterinary journal    May 1, 1992   Volume 24, Issue 3 163-164 doi: 10.1111/j.2042-3306.1992.tb02806.x
Evans P, Riggs C.No abstract available