Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Neira-Egea P, Alamar Malvoisin C, de la Cuesta-Torrado M, Bautista-Erler C, Vitale V, Jolly S, Cesarini C. spp. are ubiquitous yeasts that are part of most mammals' microbiota and can become opportunistic pathogens under predisposing conditions. Interestingly, recent studies in human medicine report an increased abundance of spp. in association with inflammatory bowel disease (IBD). Gastrointestinal candidiasis has been primarily reported in neonatal foals, but not in adult horses. The aim of this study is to describe the morphological, histopathological, and microbiological features of gastric lesions associated with infiltration in five horses referred to two tertiary hospitals for different r...
Gandini M, Bertone C, Giusto G.Castration remains a common surgical procedure in equids, yet postoperative complications such as hemorrhage, infection, and eventration persist, influencing surgical outcomes. This retrospective study introduced a novel modified semi-closed castration technique aimed at minimizing these complications. Eighty-five sexually intact mature male equids (including horses, ponies, and donkeys) underwent the described inguinal castration procedure under general anesthesia. The technique involved a carefully managed opening and subsequent secure closure of the parietal vaginal tunic, enabling direct i...
Menzies-Gow NJ.Pituitary pars intermedia dysfunction (PPID) is a common, slowly progressive, neurodegenerative disorder of the older horse. Oxidative damage to the hypothalamic periventricular neurons results in loss of dopaminergic inhibition of the pars intermedia region of the pituitary gland. Consequently, there is increased production of the pro-opiomelanocortin (POMC)-derived hormones normally produced by this region, as well as initial melanocyte hypertrophy and hyperplasia, followed by adenomatous change. Clinical signs that are highly suggestive of the disease are generalised and regional hypertrich...
Kovarikova S, Blahova J, Steffenova V, Vaskova N, Jahn P.Currently, there is relatively little published information on the urine protein-to-creatinine (UPC) ratio in horses, a parameter commonly used in dogs and cats. The aim of this study was to determine the reference range of UPC in urine samples of apparently healthy horses and to assess the influence of age and sex. Urinalysis and the determination of urinary protein and creatinine concentrations and ratios were performed. A total of 118 urine samples from apparently healthy horses were included in the study: 10 from foals younger than 6 months and 108 from horses older than 1 year. The median...
Valderrama-Martinez C, Packham A, Smith W, Mendoza-Flores JE, Zheng S, Chigerwe M, Plancarte M, Aleman M.Long-term freezing storage can alter the stability of proteins, thereby compromising accurate determination of indirect fluorescent antibody test (IFAT) titers that support the diagnosis of equine protozoal myeloencephalitis. Objective: Assess the effect of long-term storage at -80°C on IFAT against S. neurona and N. hughesi in equine serum and cerebrospinal fluid (CSF). Methods: Paired serum and CSF (n = 46), and serum only (n = 25) samples. Methods: Prospective study of samples stored 6-12, 13-18, and 19-24 months. Comparing antibody titers across time points, McNemar and Wilcoxon...
Zhang Z, Li J, Mai Z, Yang Y, Fu H, Cao X, Li T, Guo Q, Ma Y.The incidence of sports injuries in horses is increasing, thus accurate assessment, diagnosis, and treatment are critical. Among common sports-related injuries, proximal sesamoid bone fractures (PSBFs) are one of the most frequent types. To investigate the effects of low-intensity pulsed ultrasound (LIPUS) on imaging and hematological parameters of PSBFs, providing a clinical reference for the diagnosis and treatment of PSBFs in racehorses. After clinical diagnosis and radiographic examination confirmed the disease and its location, the affected horses were randomly divided into two groups: th...
de Chaisemartin C, Vandeweerd JM, Schramme M.Comminuted fractures of the proximal phalanx (CFPP) occur in adult horses. Various treatments have been described. It remains uncertain which is the best therapeutic option. Objective: This study aims to review systematically the existing literature on CFPP in horses, evaluate treatment modalities, synthesise outcomes to assess treatment efficacy and survival rates, and identify knowledge gaps for future research. Methods: Scoping review. Methods: A literature search was conducted using online databases. The bias quality of each article was evaluated. Chi-squared analysis was used to detect di...
Shimizu Y, Sugai-Bannai M, Tanabe H, Saito K, Ito H, Tokushige H, Kamiya K, Hirano-Kodaira M, Yamada M, Leung GN.Somapacitan is the second generation of recombinant human growth hormone (rhGH) medication that retains the pharmacological effects of rhGH but exhibits a longer duration of action due to its reversible albumin-binding in the body. In general, the use of all recombinant growth hormone (rGH) analogues is banned by the human and animal sports regulatory authorities due to their anabolic and lipolytic effects. However, little is known about the elimination kinetics and biological effects of the newly introduced long-acting rhGH, somapacitan, in horses. This paper describes the administration stud...
Hoh RL, Mama KR, Morales CJ, McKemie DS, Kass PH, Knych HK.To assess absorption after transdermal application of buprenorphine to different sites and assess behavioral, antinociceptive and adverse effects. It was hypothesized that the dose and site of transdermal buprenorphine administration would influence absorption, plasma drug concentrations, physiological, antinociceptive and behavioral effects in horses. Methods: Two-part study; prospective randomized balanced three-way crossover (study 1) and single-dose (study 2) experimental study. Methods: Six (study 1) and eight (study 2) horses, aged 3-14 years. Methods: In study 1, horses were administere...
Fehin B, Scott CJ, Arango-Sabogal JC, de Mestre AM, Mouncey R.To date, relationships between pre-covering endometrial swab cytology and bacteriology and fertility outcomes in Thoroughbred broodmares in the United Kingdom are unknown and could aid clinical decision making. Objective: To investigate associations between cytology and bacteriology findings from the last endometrial swab taken in the breeding season (15 February to 15 July) and live-foal rates (predicted mean probability of producing a live foal) in UK Thoroughbred broodmares. Methods: Retrospective cohort study. Methods: Endometrial cytology and bacteriology findings were extracted from labo...
Ceriotti S, Clark-Price S, Cole R, Kramer A, Sandey M, Mora M.This case describes a 15-year-old Thoroughbred mare with fistulous withers that progressed to vertebral osteomyelitis and spinal epidural abscess (SEA), a severe complication that has yet to be reported. Initially treated with antibiotics and anti-inflammatory medication, the mare developed acute hindlimb ataxia and spastic paresis, suggesting spinal cord compression at T3-L3. Diagnostic imaging revealed vertebral fractures and abscessation, but vertebral canal involvement could not be confirmed. Despite aggressive medical therapy, including antimicrobials, corticosteroids, and neuroprotective...
Chinyere CN, Ajaebili AC, Peter-Ajuzie IK, Galadima HB, Daodu OB, Fatola OI, Okolo CC, Alaba BA, Akinniyi OO, Omoniwa DO, Edeh ER, Olorunfemi AB....African horse sickness (AHS) is a severe, infectious arthropod-borne disease of equids caused by the AHS virus (AHSV). It is endemic in Sub-Saharan Africa, and several sporadic outbreaks of the disease have been reported in Nigeria in the past 5 decades. Following a recent outbreak of the disease in Lagos State, this study was conducted to investigate the prevalence of (AHSV) antibodies in apparently healthy horses and some selected wildlife sampled in four geographical regions of Nigeria. Using a competitive enzyme-linked immunosorbent assay, 575 serum samples collected from horses in five ...
Mukhanbetkaliyev Y, Yessembekova G, Mukhanbetkaliyeva A, Akmambayeva B, Kadyrov A, Uskenov R, Bostanova S, Ashirbek A, Korennoy F, Abdrakhmanov S.Equine herpesvirus 1 (EHV-1) is one of the most dangerous viral diseases affecting ungulates, and is characterized by a wide range of clinical manifestations in horses, including rhinopneumonia, abortion, neonatal death, and myeloencephalopathy. It is well known for causing mass abortions in mares and respiratory diseases in young animals. Once introduced into a horse breeding farm of any type, EHV-1 tends to establish as a persistent infection. The disease is reported on nearly all continents and causes substantial annual economic losses to horse breeding operations. In Kazakhstan, 34 EHV-1 o...
Crosby CE, O'Connor A, Munsterman AS.Colic is a significant source of morbidity and mortality in horses, and no single biomarker can distinguish surgical from medical colic or predict mortality. Alactic base excess (ABE) has shown an association with mortality and renal insufficiency in humans but has not been evaluated in veterinary species. The purpose of this study was to determine the value of ABE as a diagnostic tool for horses treated for gastrointestinal disease. Unassigned: This retrospective case series evaluated horses admitted for acute gastrointestinal disease over a 5-year period (2019-2024). Signalment, physical exa...
Roth LSV, McGreevy P.To improve human-horse interactions and reduce the risk of injury, it is essential to adopt an equi-centric perspective that prioritizes how horses perceive their environment. This review focuses on the equine visual system, both because it is the most studied of the horse's senses and because misunderstandings about how horses see can lead to unsafe or unsustainable handling. By applying two complementary frameworks, namely Tinbergen's Four Questions and the Five Domains model, we examine equine vision from both a biological and a welfare-oriented perspective. We explore the anatomical and fu...
Dong-Ha L, Eun-Bee L, Jong-Pil S, Eun-Ju K.Despite routine vaccination, equine influenza outbreaks occur due to disparities of virus strains between vaccine and field, and immunity gaps between vaccinations. Objective: To evaluate whether a combination of adjuvants can enhance immune responses to equine influenza virus (EIV) vaccines. Methods: In vivo experimental study. Methods: Eight mixed-breed horses were immunised intramuscularly with a recombinant canarypox-based EIV vaccine, either alone or in combination with monophosphoryl lipid A (MPL) and polyinosinic-polycytidylic acid (poly I:C). A single vaccine dose was administered, and...
Harder J, Fürst AE, Montavon PM, Montavon S, Bakony M, Lanyi K.Calcium dobesilate has recently been used for treating lameness in horses because it enhances microvascular processes and reduces intraosseous pressure. Lameness caused by disorders in bone metabolism and increased intraosseous pressure, such as navicular disease, osseous cyst-like lesions and pedal bone oedema, are commonly treated with rest, anti-inflammatory agents and surgery. Calcium dobesilate has the potential to influence the pathophysiology of these diseases, thereby improving healing. To determine whether calcium dobesilate and its acting agent calcium 2,5-dihydroxybenzene sulfonate ...
Norman AJ, Turner CM, Manfredi JM.Sedation is important for safe equine dental procedures, but it is unknown if there is a higher risk of sedation causing hypothermia in procedures performed during cold months. The authors hypothesize that sedation for a dental procedure will significantly decrease rectal body temperature in cold as compared to warm ambient temperatures. Adult equids ( = 246), from a private equine dentistry practice, that underwent dental equilibration, were selected for the study. Each horse's weight was estimated and sedation was administered intravenously (0.01 mg/kg detomidine and 0.01 mg/kg butor...
Silva GLS, Curcio UA, Boufleur JA, Borges DGL, Nakatani MTM, Freitas MG, Borges FA, Faria FJC, Silva RHP, Franco GL.Anthelmintic resistance has led to the use of organic extracts as alternative methods of parasite control. Objective: The study aimed to assess the effects of Acacia mearnsii extract (tannin) on the control of cyathostomins in horses, both in vitro and in vivo. Methods: Thirty Pantaneiro horses naturally infected with cyathostomins were sourced from two distinct farms, designated as Farms A and B. At the start of the study, all third-stage larvae were cyathostomins, and an egg hatchability test (EHT) was performed using fecal samples from horses on both farms. Two randomized 28-day field studi...
Hardefeldt L, Thomas K, Page S, Norris J, Browning G, El Hage C, Stewart A, Gilkerson J, Muscatello G, Verwilghen D, van Galen G, Bauquier J....The growing problem of antimicrobial resistance also affects equine veterinarians with increasing frequency. Antimicrobial stewardship and responsible prescribing are essential for a future in which effective antimicrobials are available, as it is unlikely that new antimicrobials will become available for use in horses. While antimicrobials are commonly used to treat equine infections, complications with therapy are also relatively common. Antimicrobial-associated diarrhoea, immune-mediated diseases, and nephrotoxicity have been reported as sequelae of antimicrobial therapy in equine practice....
Plotsker NM, Taylor R, Coffin HR, Beatty A, Newbold G, Knickelbein KE.To describe the clinical and histologic features of a sarcoid arising from the medial caruncle with spread to the third eyelid of a horse. Methods: A 20-year-old Quarter Horse gelding. Methods: An incisional biopsy of the medial caruncle mass was initially performed, with histopathology suggesting a sarcoid or other spindle cell neoplasm. The mass grew rapidly following the biopsy, expanding to affect the third eyelid and adjacent superior palpebral conjunctiva. A complete third eyelid and medial caruncle excision with resection of affected palpebral conjunctiva and adjunctive cryotherapy was ...
Paganelli GC, Schott HC.Small intestinal (SI) distension and gastric reflux (GR) are common in horses with mechanical and functional ileus. Removal of GR results in fluid/ion losses. Objective: 1) Determine the capacity of healthy SI; 2) measure ion concentrations in normal SI fluid, GR, or fluid from SI undergoing resection. The authors hypothesized that Na and Cl concentrations would be lower and higher, respectively, in GR as compared to SI fluid from healthy horses, while there would be little difference in K concentration. Methods: Observational study: two to 15 meters of SI from 15 horses were distended with wa...
Yeomans A, Martinkovich D, O'Brien T, O'Neill H, Carpenter R, Georgetti M, Cramp P.Standing fracture repair has become established as an acceptable technique with a good long-term prognosis. However, no study has compared racing outcomes with case-matched controls. Objective: To compare racing outcomes between a large dataset of horses undergoing standing fracture repair against case-matched controls. Methods: Retrospective case-matched controlled comparative study. Methods: Thoroughbred racehorses undergoing standing repair of distal limb fracture(s) over 10 years (2012-2022) at five hospital centres across North America and Europe were included. Data retrieved included...
Beeston TJ, Duncan JC, Pollock PJ.Surgical safety checklists have demonstrated a positive impact on post-surgical morbidity/mortality in human medicine, and likely have an equal benefit in veterinary medicine. To realise their advantages, they must be correctly and regularly used. A clinical audit was planned to assess this. Objective: To determine the compliance with the pre-procedural request form/surgical safety checklist in a large multi-disciplinary equine referral hospital. Methods: Retrospective full-cycle clinical audit. Methods: One hundred and forty-eight checklists (consisting of 23 sub-sections) were examined for c...
Guerri G, Bandera L, Straticò P, Palozzo A, Di Nunzio L, Celani G, Varasano V, Vignoli M, Petrizzi L.Superficial digital flexor tendon (SDFT) injuries cause progressive loss of its mechanical properties. Two-dimensional shear wave elastography (2D-SWE) provides information about tissue stiffness. Objective: To determine the feasibility, repeatability, and reproducibility of 2D-SWE of healthy and pathological forelimb SDFT. Methods: Prospective observational cohort study. Methods: Horses were divided into a noninjured Group (H) and a Group with tendinopathy of the SDFT (P). 2D-SWE of both fore SDFTs was performed at three metacarpal levels (A, B, and C, from proximal to distal). Qualitative an...
Whitlock F, Newton R, King S, Ionescu AM, Higgins S.With the geographical distribution of West Nile virus expanding, there is growing concern about the potential for an incursion to the UK. Here, Fleur Whitlock, Richard Newton, Simon King, Andra-Maria Ionescu and Sara Higgins provide a timely reminder of key aspects of the virus' biology.
Cullen JN, Cieslak J, Petersen JL, Bellone RR, Finno CJ, Kalbfleisch TS, Calloe K, Capomaccio S, Cappelli K, Coleman SJ, Distl O, Durward-Akhurst SA....MicroRNAs (miRNAs) are essential regulators of gene expression, yet few comprehensive databases exist for miRNA expression in non-model species, limiting our ability to characterize their roles in gene regulation, development, and disease. Similarly, isomiRs - length and sequence isoforms of canonical miRNAs with potentially altered regulatory targets and functions - have received even less attention in non-model species, including the horse, leaving a critical gap in our understanding of their biological significance. To address these challenges, we developed an open-source, containerized pip...
Gutierrez SO, Garcia-Lopez JM, Chope KB, Levine DG, Ortved K, Brown KA.To describe the clinical and ultrasonographic findings in horses with desmopathy of the abaxial palmar/plantar ligament (APL) of the proximal interphalangeal joint and the prevalence of concurrent musculoskeletal injuries in the pastern and foot. Unassigned: Horses presenting to New Bolton Center between March 2017 and November 2022 with an age ranging from 5 to 20 years that underwent lameness evaluation in which lameness was localized to the distal limb and had an ultrasonographic diagnosis of APL desmopathy. Unassigned: Horses included were those that (1) presented for a lameness examinatio...
