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Topic:Veterinary Medicine

Veterinary medicine for horses encompasses the study and application of medical practices to diagnose, treat, and prevent diseases in equine species. This field involves a comprehensive understanding of equine anatomy, physiology, pathology, and pharmacology. Veterinary practitioners employ a range of diagnostic tools and therapeutic interventions to address health issues in horses, including lameness, gastrointestinal disorders, respiratory conditions, and infectious diseases. Preventative care, such as vaccination and deworming programs, is also a significant aspect of equine veterinary medicine. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary medicine as it pertains to horses, including advancements in diagnostic techniques, treatment protocols, and preventive health strategies.
Individual speed dependency of forelimb lameness in trotting horses.
Veterinary journal (London, England : 1997)    September 14, 2000   Volume 160, Issue 2 135-138 doi: 10.1053/tvjl.2000.0483
Peham C, Licka T, Mayr A, Scheidl M.Using a system for motion analysis, linear correlation of speed and forelimb lameness was measured in 16 horses trotting on a treadmill at a minimum of three different trotting speeds. Forelimb lameness was determined as asymmetry of vertical head motion during left and right forelimb stance. In seven horses with a moderate forelimb lameness (head motion asymmetry >40%), lameness increased significantly with trotting speed. In a further seven horses with mild or subclinical forelimb lameness (head motion asymmetry <40%) and in two horses with a moderate forelimb lameness, no significant ...
The effects of bovine recombinant growth hormone administration on insulin-like growth factor-I and the haemopoietic system in thoroughbred geldings.
Veterinary journal (London, England : 1997)    September 14, 2000   Volume 160, Issue 2 147-152 doi: 10.1053/tvjl.2000.0485
Champion ZJ, James EA, Vickers MH, Breier BH, Casey PJ.The effect of intramuscularly administered recombinant bovine growth hormone (rbGH) on insulin-like growth factor-I (IGF-I) and white and red blood cell indices was studied in Thoroughbred geldings. An insulin-like growth factor binding protein (IGFBP)-blocked radioimmunoassay was modified and validated for the measurement of IGF-I in equine blood plasma. Baseline values of IGF-I and blood indices were determined over a 48 h period and then a single dose of 5 microg/kg, 10 microg/kg or 50 microg/kg of rbGH was administered. Insulin-like growth factor-I levels increased in a dose-dependent mann...
Climate change: effects on culicoides–transmitted viruses and implications for the UK.
Veterinary journal (London, England : 1997)    September 14, 2000   Volume 160, Issue 2 107-117 doi: 10.1053/tvjl.2000.0470
Wittmann EJ, Baylis M.Changes in the distribution and abundance of insects are likely to be amongst the most important and immediate effects of climate change. We review here the risk that climate change poses to the UK's livestock industry via effects on Culicoides biting midges, the vectors of several arboviruses, including those that cause bluetongue (BT) and African horse sickness (AHS). The major old-world vector of BT and AHS viruses, C. imicola, occurs in southern Europe and will spread further north as global temperatures increase. It is unlikely, however, that in the foreseeable future it will reach and be...
Energy expenditure of horse riding.
European journal of applied physiology    September 14, 2000   Volume 82, Issue 5-6 499-503 doi: 10.1007/s004210000207
Devienne MF, Guezennec CY.Oxygen consumption (VO2), ventilation (VE) and heart rate (HR) were studied in five recreational riders with a portable oxygen analyser (K2 Cosmed, Rome) telemetric system, during two different experimental riding sessions. The first one was a dressage session in which the rider successively rode four different horses at a walk, trot and canter. The second one was a jumping training session. Each rider rode two horses, one known and one unknown. The physiological parameters were measured during warm up at a canter in suspension and when jumping an isolated obstacle at a trot and canter. This s...
The effect of initiation of exercise training in young horses on vitamin K status.
Journal of animal science    September 14, 2000   Volume 78, Issue 9 2353-2358 doi: 10.2527/2000.7892353x
Siciliano PD, Kawcak CE, McIlwraith CW.Twelve Quarter Horses, 18 to 24 mo of age and having an average body weight of 460+/-12 kg, were randomly assigned to one of two exercise treatments (control and exercise) to study the effect of initiation of exercise training in young horses on vitamin K status. The control treatment consisted of hand-walking the horses 7 min/d and 5 d/wk for 180 d. Exercise consisted of the following treadmill exercise regimen: 2 min at 4.5 to 5.4 m/s, 3 min at 13.4 to 14.3 m/s, and 2 min at 4.5 to 5.4 m/s on 5 d/wk for 180 d. Both groups were allowed free access to brome grass hay (273 mg of phylloquinone/1...
Treatment of traumatically induced synovial sepsis in horses with gentamicin-impregnated collagen sponges.
The Veterinary record    September 14, 2000   Volume 147, Issue 7 184-188 doi: 10.1136/vr.147.7.184
Summerhays GE.Eight horses with synovial sepsis induced by trauma were treated by arthroscopic/tenoscopic debridement and lavage followed by the implantation of a gentamicin-impregnated collagen sponge. Seven of them responded favourably and were sound six months after treatment. The other underwent a further surgical procedure and recovered. Gentamicin-impregnated collagen sponges appear to be a safe and useful adjunct in the treatment of septic joints and tendon sheaths, and have the advantage of being bioabsorbable.
Efficient homologous RNA recombination and requirement for an open reading frame during replication of equine arteritis virus defective interfering RNAs.
Journal of virology    September 12, 2000   Volume 74, Issue 19 9062-9070 doi: 10.1128/jvi.74.19.9062-9070.2000
Molenkamp R, Greve S, Spaan WJ, Snijder EJ.Equine arteritis virus (EAV), the prototype arterivirus, is an enveloped plus-strand RNA virus with a genome of approximately 13 kb. Based on similarities in genome organization and protein expression, the arteriviruses have recently been grouped together with the coronaviruses and toroviruses in the newly established order Nidovirales. Previously, we reported the construction of pEDI, a full-length cDNA copy of EAV DI-b, a natural defective interfering (DI) RNA of 5.6 kb (R. Molenkamp et al., J. Virol. 74:3156-3165, 2000). EDI RNA consists of three noncontiguous parts of the EAV genome fused ...
Bacterial infection of the lower respiratory tract in 34 horses.
Australian veterinary journal    September 9, 2000   Volume 78, Issue 8 549-559 doi: 10.1111/j.1751-0813.2000.tb11901.x
Racklyeft DJ, Love DN.To investigate associations between the bacteriology and aspects of history, clinical presentation, outcome and pathology of lower respiratory tract disease of 34 horses. Methods: Detailed aerobic and anaerobic bacteriological investigations were performed on clinical specimens from horses with pneumonia, lung abscessation and necrotic pneumonia with or without pleurisy in an attempt to identify those bacteria that might contribute to the initiation and progression of infection. Results: Bacteria were cultured from 33 of the 34 horses. In ten cases, only aerobic/facultatively anaerobic isolate...
Tensions used on girths on thoroughbred racehorses.
Australian veterinary journal    September 9, 2000   Volume 78, Issue 8 567-569 doi: 10.1111/j.1751-0813.2000.tb11904.x
Bowers J, Slocombe R.To determine commonly used girth tensions in Thoroughbred racehorses in the Melbourne metropolitan area. Methods: A prospective industry survey. Methods: Strappers were instructed to tension girths, using the same saddle, under-saddle packing and girth, sufficiently to hold the saddle for racing. These tensions were continuously recorded by an in-line load cell in the girth. Seventeen strappers from five stables participated in the study, which was conducted on 91 horses. Results: Resting girth tensions varied considerably. The mean tension on inhalation was 13 +/- 0.4 kg. Male strappers recor...
Kinematics of the hind limb in trotting horses after induced lameness of the distal intertarsal and tarsometatarsal joints and intra-articular administration of anesthetic.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1031-1036 doi: 10.2460/ajvr.2000.61.1031
Kramer J, Keegan KG, Wilson DA, Smith BK, Wilson DJ.To identify hind limb and pelvic kinematic variables that change in trotting horses after induced lameness of the distal intertarsal and tarsometatarsal joints and after subsequent intra-articular administration of anesthetic. Methods: 8 clinically normal adult horses. Methods: Kinematic measurements were made before and after transient endotoxin-induced lameness of the distal intertarsal and tarsometatarsal joints and after intra-articular administration of anesthetic. Fourteen displacement and joint angle (metatarsophalangeal [fetlock] and tarsal joints) measurements were made on the right h...
Use of body condition scores in clinical assessment of the provision of optimal nutrition.
Journal of the American Veterinary Medical Association    September 8, 2000   Volume 217, Issue 5 650-654 doi: 10.2460/javma.2000.217.650
Burkholder WJ.No abstract available
Concentrations of elastinolytic metalloproteinases in respiratory tract secretions of healthy horses and horses with chronic obstructive pulmonary disease.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1067-1073 doi: 10.2460/ajvr.2000.61.1067
Raulo SM, Sorsa TA, Maisi PS.To determine whether samples of tracheal epithelial lining fluid (TELF) obtained from horses have elastinolytic activity characteristic of metalloproteinases, to compare elastinolytic activity in TELF obtained from healthy horses and horses with chronic obstructive pulmonary disease (COPD), and to determine whether chemically modified tetracycline-3 (CMT-3) inhibits elastinolytic activity in TELF ANIMALS: 10 horses with COPD and 10 healthy control horses. Methods: Zymography and fluorometry were used to measure elastinolytic activity, and EDTA was used to inhibit elastinolytic activity and ver...
Pseudallescheria boydii infection of the nasal cavity of a horse.
Journal of the American Veterinary Medical Association    September 8, 2000   Volume 217, Issue 5 707-674 doi: 10.2460/javma.2000.217.707
Davis PR, Meyer GA, Hanson RR, Stringfellow JS.An 18-year-old 454-kg (1,000-lb) American Quarter Horse gelding was evaluated because of chronic intermittent malodorous right-sided nasal discharge. Endoscopy revealed a mycotic plaque in the nasal cavity adjacent to the nasomaxillary opening of the right caudal maxillary sinus. The nasomaxillary opening appeared to be larger than normal. Fungal culture of specimens of the mycotic plaque yielded Pseudallescheria boydii. The horse was treated with 2% miconazole intranasally, sodium iodide i.v., and potassium iodide p.o. Thirty and 60 days after treatment was initiated, the nasal cavity was fou...
Catalase activity in equine semen.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1026-1030 doi: 10.2460/ajvr.2000.61.1026
Ball BA, Gravance CG, Medina V, Baumber J, Liu IK.To characterize the activity of catalase in equine semen. Methods: 15 stallions of known and unknown reproductive history. Methods: Seminal plasma was collected from raw equine semen by centrifugation, and samples of seminal plasma were frozen prior to assay for catalase activity. Tissue samples (n = 3 stallions) from the bulbourethral gland, prostate gland, vesicular gland, and testis were homogenized, and cauda epididymal fluid was collected for determination of catalase activity. Catalase activity was determined as an enzyme kinetic assay by the disappearance of H2O2 as measured by ultravio...
Effect of transforming growth factor beta1 on chondrogenic differentiation of cultured equine mesenchymal stem cells.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1003-1010 doi: 10.2460/ajvr.2000.61.1003
Worster AA, Nixon AJ, Brower-Toland BD, Williams J.To determine the morphologic and phenotypic effects of transforming growth factor beta1 (TGFbeta1) on cultured equine mesenchymal stem cells (MSC) and articular chondrocytes. Methods: Bone marrow aspirates and articular cartilage samples from a 2-year-old and two 8-month-old horses. Methods: After initial isolation and culture, MSC and chondrocytes were cultured in Ham's F-12 medium supplemented with TGF-beta1 at a concentration of 0, 1, 5, or 10 ng/ml. Medium was exchanged on day 2, and cells were harvested on day 4. Medium was assayed for proteoglycan (PG) content. Total RNA was isolated fro...
Use of an extracorporeal circuit to evaluate effects of ischemia and reperfusion of the equine large colon.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1042-1051 doi: 10.2460/ajvr.2000.61.1042
Van Hoogmoed LM, Snyder JR, Nieto JE, Vatistas NJ, Harmon FA.To determine efficacy of an extracorporeal circuit to maintain a segment of equine large colon for 3.5 hours and to evaluate the effect of low arterial flow on histologic and metabolic variables. Methods: Segments of large colon from 15 healthy adult horses. Methods: The pelvic flexure was surgically removed and maintained in an isolated circuit. In the control group, tissue was evaluated for 3.5 hours, whereas in the low-flow group, arterial flow was reduced to 20% of baseline for 40 minutes followed by 2 hours of reperfusion. Various metabolic and hemodynamic variables were evaluated at 30-m...
Effect of pyloric blockade and infusion of histamine or pentagastrin on gastric secretion in horses.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1133-1139 doi: 10.2460/ajvr.2000.61.1133
Kitchen DL, Burrow JA, Heartless CS, Merritt AM.To determine the origin of the nonacid (nonparietal) component of gastric secretions in horses induced by pentagastrin infusion. Methods: 6 horses. Methods: A Latin square design was used, involving 6 horses, 3 treatments, and 2 duodenal intubation conditions (catheter with balloon to obstruct pylorus [B] or without balloon allowing movement of contents between stomach and duodenum [NB]). Each horse had an indwelling gastric cannula and a catheter positioned in the duodenum. Gastric and duodenal contents were collected during 15-minute periods. Each experiment consisted of serial collection pe...
Effects of prior feeding on pharmacokinetics and estimated bioavailability after oral administration of a single dose of microencapsulated erythromycin base in healthy foals.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1011-1015 doi: 10.2460/ajvr.2000.61.1011
Lakritz J, Wilson WD, Marsh AE, Mihalyi JE.To determine effects of prior feeding on pharmacokinetics and estimated bioavailability of orally administered microencapsulated erythromycin base (MEB) in healthy foals. Methods: 6 healthy foals, 3 to 5 months old. Methods: Foals were given 2 doses of MEB (25 mg/kg of body weight, PO). One dose was administered after food was withheld overnight, and the other was administered after foals had consumed hay. The study used a crossover design with a 2-week period between doses. Blood was collected via a jugular vein prior to and at specific times after drug administration. Concentrations of eryth...
What is your diagnosis? Atlanto-occipital luxation.
Journal of the American Veterinary Medical Association    September 8, 2000   Volume 217, Issue 5 647-648 doi: 10.2460/javma.2000.217.647
Scharmer BL, Trostle SS, Nelson KM, O'Brien RT.No abstract available
Effect of topical administration of epidermal growth factor on healing of corneal epithelial defects in horses.
American journal of veterinary research    September 8, 2000   Volume 61, Issue 9 1150-1155 doi: 10.2460/ajvr.2000.61.1150
Burling K, Seguin MA, Marsh P, Brinkman K, Madigan J, Thurmond M, Moon-Massat P, Mannis M, Murphy CJ.OBJECTIVE-To characterize healing of corneal epithelial defects in horses and to evaluate the ability of epidermal growth factor (EGF) to modulate rate of corneal epithelial healing in horses. Methods: 20 eyes in 12 adult horses. Methods: Corneal epithelial wounds were created by mechanically debriding the limbus. Corneal healing was recorded for 3 treatment groups: 50 microg of EGF/ml (n = 5 eyes), 5 microg of EGF/ml (7), and PBS solution (8). Corneal healing was recorded once daily after instillation of fluorescein stain by use of photography and calculating the area of the wound, using imag...
Euthanasia of horses.
The Veterinary record    September 7, 2000   Volume 147, Issue 1 28 
Baird J.No abstract available
Evidence of histamine receptor function in isolated horse penile dorsal arteries.
Life sciences    September 6, 2000   Volume 67, Issue 11 1355-1368 doi: 10.1016/s0024-3205(00)00724-4
Martínez AC, Rivera L, Raposo R, García-Sacristán A, Benedito S.The effect of histamine (10(-9)-10(-3) M) on horse penile dorsal artery was evaluated. Precontracted vessels showed a biphasic response (relaxation-contraction) to histamine, while at basal tone, histamine only induced a contractile effect. The H1 receptor agonist, 2-pyridylethylamine (PEA) (10(-9)-10(-3) M), induced concentration-dependent relaxation in precontracted rings and provoked vasoconstriction at basal tone. Mepyramine (10(-9)-10(8) M), an H1 receptor antagonist, competitively antagonized the relaxant response to histamine (pA2 = 9.7) and PEA (pA2 = 9.2). At basal tone, mepyramine (1...
The effect of the alpha-2-adrenergic agonist, clonidine, on secretion patterns and rates of adrenocorticotropic hormone and its secretagogues in the horse.
Journal of neuroendocrinology    September 6, 2000   Volume 12, Issue 9 874-880 doi: 10.1046/j.1365-2826.2000.00542.x
Alexander SL, Irvine CH.Alpha-2-adrenoceptor activation may lower adrenocorticotropic hormone (ACTH) by reducing secretagogue input and/or increasing the release of an inhibitory factor (CIF). To investigate this, we gave clonidine, an alpha-2-agonist, to seven horses, and collected pituitary venous blood every minute for 20 min before treatment and 40 min after treatment. Six horses were given saline vehicle. Mean secretion rates of corticotrophin-releasing hormone (CRH), arginine vasopressin (AVP) and ACTH were calculated before and during four 5-min then two 10-min periods after clonidine or saline. Reduction in A...
Experimental and natural borna disease virus infections: presence of viral RNA in cells of the peripheral blood.
Veterinary microbiology    September 6, 2000   Volume 76, Issue 3 229-244 doi: 10.1016/s0378-1135(00)00242-x
Vahlenkamp TW, Enbergs HK, Müller H.Cells of the peripheral blood of experimentally and naturally borna disease virus (BDV)-infected animals and of human psychiatric patients and healthy individuals were analyzed for the presence of viral RNA using a BDV-p40-specific nested reverse transcription-polymerase chain reaction (RT-PCR). The assay proved to be highly sensitive as 10 RNA molecules were reproducibly amplified. BDV RNA was detected in blood cells of experimentally infected immunocompetent mice and rats. Mice were persistently infected without showing clinical signs of borna disease (BD), whereas the rats suffered from acu...
Cloning and sequencing of the horse and sheep high-affinity IgE receptor alpha chain cDNA.
Immunogenetics    September 2, 2000   Volume 51, Issue 10 878-881 doi: 10.1007/s002510000200
McAleese SM, Halliwell RE, Miller HR.No abstract available
Release of oxytocin and prostaglandin f(2alpha) around teasing, natural service and associated events in the mare.
Animal reproduction science    September 1, 2000   Volume 63, Issue 1-2 89-99 doi: 10.1016/s0378-4320(00)00149-4
Nikolakopoulos E, Kindahl H, Gilbert CL, Goode J, Watson ED.Mating has been shown in many species to provoke the release of oxytocin (OT). In our study, various stimuli were applied to mares to study release of OT and prostaglandin F(2alpha) (PGF(2alpha)) associated with mating. Blood samples were collected from mares around the time of teasing both in oestrus and dioestrus and at mating. For comparison, blood samples were also collected at the time of manual manipulation of the genital tract and after intrauterine infusion of 500 ml phosphate buffered saline (PBS). Additional samples were collected 16 to 18 h after mating. Mating caused a significant ...
Immunologic diseases.
Veterinary dermatology    September 1, 2000   Volume 11, Issue 3 163-178 doi: 10.1046/j.1365-3164.2000.00222.x
Selected equine cutaneous diseases for which there is strong evidence of an immunological aetiology are discussed in this section. The reactive disorders of urticaria, Culicoides hypersensitivity, erythema multiforme, drug eruptions and systemic granulomatous disease are included. The autoimmune diseases of the horse with cutaneous manifestations (pemphigus foliaceus, pemphigus vulgaris, bullous pemphigoid and cutaneous lupus erythematosus) are discussed. The clinical signs and diagnostic features of these immunologically induced equine dermatoses are defined, and the challenges in making a de...
Miscellaneous.
Veterinary dermatology    September 1, 2000   Volume 11, Issue 3 217-223 doi: 10.1046/j.1365-3164.2000.00228.x
This section includes clinical conditions which have unique characteristics which make them unsuitable for inclusion in the first six sections. The clinical description, aetiology and histopathologic findings of the unusual ear lesion, aural plaques, are described. Dermatoses complicated by, or caused by, photosensitivity are discussed in regards to their aetiology and pathogenesis as well as clinical features. The suggestion that photosensitization plays a role in the development of the lesions seen in pastern leukocytoclastic vasculitis is made. This section ends with an in depth discussion ...
Effect of intrauterine treatment with prostaglandin E2 prior to insemination of mares in the uterine horn or body.
Theriogenology    September 1, 2000   Volume 53, Issue 9 1827-1836 doi: 10.1016/s0093-691x(00)00318-6
Woods J, Rigby S, Brinsko S, Stephens R, Varner D, Blanchard T.Two trials were conducted to investigate the effects of intrauterine infusion of PGE2 and uterine horn insemination on pregnancy rates in mares achieved by breeding with a suboptimal number of normal spermatozoa. Estrus was synchronized and mares were teased daily with a stallion to detect estrus. Mares in estrus were examined by transrectal palpation and ultrasonography to monitor follicular status. On the first day a 35-mm diameter follicle was present, hCG (1500 IU, iv) was administered and the mares were bred the next day. Mares (Trial 1, n = 34; Trial 2, n = 28) were inseminated with 25 m...
Stannard’s Illustrated Equine Dermatology Notes – an introduction.
Veterinary dermatology    September 1, 2000   Volume 11, Issue 3 161-162 doi: 10.1046/j.1365-3164.2000.00220.x
Von Tscharner , Kunkle , Yager .No abstract available