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Topic:Veterinary Science

Veterinary science and horses encompass the study and application of medical, surgical, and therapeutic practices to maintain and improve the health and welfare of equines. This field addresses a wide range of topics, including disease prevention, diagnosis, and treatment, as well as nutrition, reproduction, and behavior. Research in veterinary science for horses often involves understanding the pathophysiology of equine-specific diseases, developing advanced diagnostic techniques, and improving treatment protocols. This page gathers peer-reviewed research studies and scholarly articles that explore various aspects of veterinary science related to horses, providing insights into the latest advancements and methodologies in equine healthcare.
Dynamic host-bacteria interactions during an acidotic state induction.
Environmental microbiology reports    February 1, 2011   Volume 3, Issue 1 101-105 doi: 10.1111/j.1758-2229.2010.00193.x
Rudi K.Mainly due to the lack of time-series data, we know very little about the underlying interactions leading to adverse states in the gut. I therefore investigate the host-bacteria dynamic interactions in a recently published acidotic state induction time-series experiment. Too high levels of fermentation in the hindgut may lead to elevated serum lactate levels, which is a characteristic of the acidotic state. The acidotic state was induced through injection of oligofructose directly into the caecum of five horses, with subsequent temporal measurements of host serum lactate, and a range of caecum...
The effect of age on thoroughbred racing performance.
Journal of equine science    January 29, 2011   Volume 21, Issue 4 73-78 doi: 10.1294/jes.21.73
Gramm M, Marksteiner R.Using a dataset of 274 male Thoroughbred racehorses in the United States, we study the effect of age on racing performance. Beyer speed figures, which are uniform measures of racing performance across distance and racing surface, are utilized in this study. A system of equations is estimated to determine quadratic improvement and decline in racing performance. We find that a typical horse's peak racing age is 4.45 years. The rate of improvement from age 2 to 4 1/2 is greater than the rate of decline after age 4 1/2. A typical horse will improve by 10 (horse) lengths in sprints (less than 1 mil...
The effect of age on thoroughbred racing performance.
Journal of equine science    January 29, 2011   Volume 21, Issue 4 73-78 doi: 10.1294/jes.21.73
Gramm M, Marksteiner R.Using a dataset of 274 male Thoroughbred racehorses in the United States, we study the effect of age on racing performance. Beyer speed figures, which are uniform measures of racing performance across distance and racing surface, are utilized in this study. A system of equations is estimated to determine quadratic improvement and decline in racing performance. We find that a typical horse's peak racing age is 4.45 years. The rate of improvement from age 2 to 4 1/2 is greater than the rate of decline after age 4 1/2. A typical horse will improve by 10 (horse) lengths in sprints (less than 1 mil...
Chromatin configuration and epigenetic landscape at the sex chromosome bivalent during equine spermatogenesis.
Chromosoma    January 28, 2011   Volume 120, Issue 3 227-244 doi: 10.1007/s00412-010-0306-5
Baumann C, Daly CM, McDonnell SM, Viveiros MM, De La Fuente R.Pairing of the sex chromosomes during mammalian meiosis is characterized by the formation of a unique heterochromatin structure at the XY body. The mechanisms underlying the formation of this nuclear domain are reportedly highly conserved from marsupials to mammals. In this study, we demonstrate that in contrast to all eutherian species studied to date, partial synapsis of the heterologous sex chromosomes during pachytene stage in the horse is not associated with the formation of a typical macrochromatin domain at the XY body. While phosphorylated histone H2AX (γH2AX) and macroH2A1.2 are pres...
Evaluation of suitable reference genes for gene expression studies in bronchoalveolar lavage cells from horses with inflammatory airway disease.
BMC molecular biology    January 28, 2011   Volume 12 5 doi: 10.1186/1471-2199-12-5
Beekman L, Tohver T, Dardari R, Léguillette R.The stability of reference genes has a tremendous effect on the results of relative quantification of genes expression by quantitative polymerase chain reaction. Equine Inflammatory Airway Disease (IAD) is a common condition often treated with corticosteroids. The diagnosis of IAD is based on clinical signs and bronchoalveolar lavage (BAL) fluid cytology. The aim of this study was to identify reference genes with the most stable mRNA expression in the BAL cells of horses with IAD irrespective of corticosteroids treatment. Results: The expression stability of seven candidate reference genes (B2...
An investigation of racing performance and whip use by jockeys in thoroughbred races.
PloS one    January 27, 2011   Volume 6, Issue 1 e15622 doi: 10.1371/journal.pone.0015622
Evans D, McGreevy P.Concerns have been expressed concerning animal-welfare issues associated with whip use during Thoroughbred races. However, there have been no studies of relationships between performance and use of whips in Thoroughbred racing. Our aim was to describe whip use and the horses' performance during races, and to investigate associations between whip use and racing performance. Under the Australian Racing Board (ARB) rules, only horses that are in contention can be whipped, so we expected that whippings would be associated with superior performance, and those superior performances would be explaine...
Communication in relation to equine infectious anaemia in Devon.
The Veterinary record    January 25, 2011   Volume 167, Issue 15 588 doi: 10.1136/vr.c5528
O'Brien K, Wildman S, Rowlands D.No abstract available
Welfare during transport: EFSA assesses the scientific evidence.
The Veterinary record    January 25, 2011   Volume 168, Issue 3 61 doi: 10.1136/vr.d339
No abstract available
Optic axis determination by fibre-based polarization-sensitive swept-source optical coherence tomography.
Physics in medicine and biology    January 25, 2011   Volume 56, Issue 4 1105-1122 doi: 10.1088/0031-9155/56/4/014
Lu Z, Kasaragod DK, Matcher SJ.We describe a fibre-based variable-incidence angle (VIA) polarization-sensitive swept-source optical coherence tomography (PS-SS-OCT) system to determine the 3D optical axis of birefringent biological tissues. Single-plane VIA-PS-OCT is also explored which requires measurement of the absolute fast-axis orientation. A state-of-the-art PS-SS-OCT system with some improvements both in hardware and software was used to determine the apparent optical birefringence of equine tendon for a number of different illumination directions. Polar and azimuthal angles of cut equine tendon were produced by the ...
Eastern equine encephalitis: an emerging arboviral disease threat, Maine, 2009.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    January 23, 2011   Volume 11, Issue 6 637-639 doi: 10.1089/vbz.2010.0189
Gibney KB, Robinson S, Mutebi JP, Hoenig DE, Bernier BJ, Webber L, Lubelczyk C, Nett RJ, Fischer M.Eastern equine encephalitis (EEE) is one of the most severe arboviral encephalitides in North America. Before 2009, limited nonhuman EEE virus activity had been reported in Maine, all from the southernmost area of the state. No human case has been reported in a Maine resident. Methods: We review all EEE virus activity reported to Maine Centers for Disease Control in 2009 and describe current testing practices for possible human EEE cases. Results: In 2009, fatal cases of EEE were identified in 15 horses, 1 llama, and 3 flocks of pheasants in Maine, with activity extending into the central part...
Advances in equine sports testing.
Drug testing and analysis    January 22, 2011   Volume 3, Issue 1 18 doi: 10.1002/dta.261
Kuuranne T.No abstract available
Usefulness of molecular-based methods for estimating effective population size in livestock assessed using data from the endangered black-coated Asturcón pony.
Journal of animal science    January 21, 2011   Volume 89, Issue 5 1251-1259 doi: 10.2527/jas.2010-3620
Goyache F, Alvarez I, Fernández I, Pérez-Pardal L, Royo LJ, Lorenzo L.Empirical evidence of the usefulness of different molecular-based methods to estimate the effective population size (N(e)) for conservation purposes in endangered livestock populations is reported. The black-coated Asturcón pony pedigree (1,981 individuals) was available. Additionally, a total of 267 Asturcón individuals born in 1998, 2002, and 2008 were typed for 15 microsatellites. These yearly cohorts (cohort(1998, 2002, 2008)) included almost all individuals kept for reproduction at the end of the corresponding foaling season. The genealogical realized N(e) was estimated for each cohort ...
Prevalence of obesity in a population of horses in the UK.
The Veterinary record    January 17, 2011   Volume 168, Issue 5 131 doi: 10.1136/vr.c6281
Stephenson HM, Green MJ, Freeman SL.No abstract available
Pharmacokinetics of yohimbine following intravenous administration to horses.
Journal of veterinary pharmacology and therapeutics    January 12, 2011   Volume 34, Issue 1 58-63 doi: 10.1111/j.1365-2885.2010.01194.x
Dimaio Knych HK, Steffey EP, Deuel JL, Shepard RA, Stanley SD.Yohimbine is an alpha 2 adrenergic receptor antagonist used most commonly in veterinary medicine to reverse the effects of the alpha 2 receptor agonists, xylazine and detomidine. Most notably, yohimbine has been shown to counteract the CNS depressant effects of alpha 2 receptor agonists in a number of species. The recent identification of a yohimbine positive urine sample collected from a horse racing in California has led to the investigation of the pharmacokinetics of this compound. Eight healthy adult horses received a single intravenous dose of 0.12 mg/kg yohimbine. Blood samples were co...
Low prevalence of Escherichia coli O157:H7 in horses in Ohio, USA.
Journal of food protection    January 12, 2011   Volume 73, Issue 11 2089-2092 doi: 10.4315/0362-028x-73.11.2089
Lengacher B, Kline TR, Harpster L, Williams ML, Lejeune JT.Manure from draft animals deposited in fields during vegetable and fruit production may serve as a potential source of preharvest pathogen contamination of foods. To better quantify this risk, we determined the prevalence of Escherichia coli O157:H7 in horses. Between June and September 2009, freshly voided fecal samples were collected from horses stabled on 242 separate premises in Ohio, USA. Overall, the prevalence of E. coli O157:H7 was 1 of 242 (0.4% prevalence, 95% confidence interval [CI] = 0.01 to 2.28). E. coli O157:H7 was recovered from none of the 107 equine fecal samples (0% prevale...
Infection by spotted fever rickettsiae in people, dogs, horses and ticks in Londrina, Parana State, Brazil.
Zoonoses and public health    January 5, 2011   Volume 58, Issue 6 416-423 doi: 10.1111/j.1863-2378.2010.01382.x
Toledo RS, Tamekuni K, Filho MF, Haydu VB, Barbieri AR, Hiltel AC, Pacheco RC, Labruna MB, Dumler JS, Vidotto O.Spotted fever is a disease caused by bacteria from the genus Rickettsia of the spotted fever group (SFG). Rickettsia rickettsii is likely the main agent of Brazilian spotted fever (BSF). With the objective of gathering information on the circulation of SFG rickettsiae in Londrina, Parana state, ticks from dogs and horses and also blood from dogs, horses and humans were collected in a neighbourhood of the city which presented potential for circulation of rickettsiae between hosts and vectors. Amblyomma cajennense, Dermacentor nitens, and Rhipicephalus sanguineus ticks were subjected to Polymera...
Highly athletic terrestrial mammals: horses and dogs.
Comprehensive Physiology    January 1, 2011   Volume 1, Issue 1 1-37 doi: 10.1002/cphy.c091001
Poole DC, Erickson HH.Evolutionary forces drive beneficial adaptations in response to a complex array of environmental conditions. In contrast, over several millennia, humans have been so enamored by the running/athletic prowess of horses and dogs that they have sculpted their anatomy and physiology based solely upon running speed. Thus, through hundreds of generations, those structural and functional traits crucial for running fast have been optimized. Central among these traits is the capacity to uptake, transport and utilize oxygen at spectacular rates. Moreover, the coupling of the key systems--pulmonary-cardio...
Understanding the equine cecum-colon ecosystem: current knowledge and future perspectives.
Animal : an international journal of animal bioscience    January 1, 2011   Volume 5, Issue 1 48-56 doi: 10.1017/S1751731110001588
Santos AS, Rodrigues MA, Bessa RJ, Ferreira LM, Martin-Rosset W.Having evolved as a grazing animal, a horse's digestive physiology is characterized by rapid gastric transit, a rapid but intense enzymatic digestion along the small intestine, and a long and intense microbial fermentation in the large intestine. The process of understanding and describing feed degradation mechanisms in the equine digestive system in general, and in the hindgut ecosystem in particular, is essential. Regardless of its importance for the nutritional status of the host, the significance of the cecum-colon ecosystem has not yet been fully understood, and few reports have focused d...
Occurrence and molecular characterization of Cryptosporidium spp. isolated from domestic animals in a rural area surrounding Atlantic dry forest fragments in Teodoro Sampaio municipality, State of São Paulo, Brazil. Sevá Ada P, Funada MR, Souza Sde O, Nava A, Richtzenhain LJ, Soares RM.The aim of this study was to assess the occurrence of Cryptosporidium in domestic animals in rural properties surrounding rain forest fragments within the municipality of Teodoro Sampaio, southeastern Brazil. Conventional sucrose flotation method followed by molecular characterization of the parasites by sequencing PCR products amplified from SSU rRNA gene were used. Stool samples were collected from domestic animals raised as pets and livestock in all rural properties surrounding three forest fragments. Samples from cattle (197), equine (63), pigs (25), sheep (11), and dogs (28) were collecte...
Serological survey of Rickettsia sp. in horses and dogs in a non-endemic area in Brazil. Batista FG, Silva DM, Green KT, Tezza LB, Vasconcelos SP, Carvalho SG, Silveira I, Moraes-Filho J, Labruna MB, Fortes FS, Molento MB.Brazilian Spotted Fever (BSF) is a lethal rickettsiosis in humans caused by the bacteria Rickettsia rickettsii, and is endemic in some areas of Brazil. Horses and dogs are part of the disease's life cycle and they may also serve as sentinel animals in epidemiological studies. The first human BSF case in the State of Paraná was reported in 2005. The present study was conducted in the municipality of Almirante Tamandaré, where no previous case of BSF was reported. Serum samples were collected from 71 horses and 20 dogs from nine properties in the area. Ticks were also collected from these anim...
Ticks on birds in a forest fragment of Brazilian cerrado (savanna) in the municipality of Uberlândia, State of Minas Gerais, Brazil. Tolesano-Pascoli GV, Torga K, Franchin AG, Ogrzewalska M, Gerardi M, Olegário MM, Labruna MB, Szabó MP, Marçal Júnior O.This is a report of tick species, parasite prevalence and infestation intensity of birds in a forest fragment (18° 56' 57'' S and 48° 12' 14'' W) within the Brazilian cerrado (savanna), in the municipality of Uberlândia, State of Minas Gerais, Brazil. A total of 162 birds from 26 species were captured. One adult tick, 296 larvae and 67 nymphs were found on passerine birds. Of these, it was identified 31 larvae and 27 nymphs of Amblyomma longirostre, 17 nymphs of A. nodosum, one A. cajennense larvae and one male of Rhipicephalus sanguineus. All other ticks were identified as Amblyomma sp. la...
Lactate-driven equine conditioning programmes.
Veterinary journal (London, England : 1997)    December 24, 2010   Volume 190, Issue 2 199-207 doi: 10.1016/j.tvjl.2010.11.012
Campbell EH.Equine conditioning programmes are rarely driven by science. Indeed, the scientific literature on conditioning responses often refers to conventional technique rather than physiological driving parameters. This, alongside poor classification of conditioning protocols, has reduced the possibility of comparative data analysis. Recent interest into lactate-driven conditioning programmes has driven this review which provides a summary of equine protocols used to date and their responses. Key areas identified for further standardisation and/or investigation include (1) the treadmill acclimation pro...
Plasma vitamin K concentration in horses supplemented with several vitamin K homologs.
Journal of animal science    December 17, 2010   Volume 89, Issue 4 1056-1061 doi: 10.2527/jas.2009-2759
Terachi T, Inoue Y, Ashihara N, Kobayashi M, Ando K, Matsui T.The effect of several vitamin K homologs on plasma vitamin K concentration was determined to assess their potential as a vitamin K supplement for adult horses. Sixteen Thoroughbred horses consisting of 8 mares and 8 geldings, aged 8.4 ± 3.6 yr and weighing 520.8 ± 36.1 kg, were allocated to 4 groups (n = 4). Each group was given phylloquinone, menaquinone-4, or menadione at 58 µmol/d, or no vitamin K supplement for 7 d. Plasma samples were collected before feeding, and 2, 4, and 8 h after feeding on d 7, and plasma concentrations of phylloquinone and menaquinone-4 were determined. Plasma ph...
Evaluation of a postexposure rabies prophylaxis protocol for domestic animals in Texas: 2000-2009.
Journal of the American Veterinary Medical Association    December 16, 2010   Volume 237, Issue 12 1395-1401 doi: 10.2460/javma.237.12.1395
Wilson PJ, Oertli EH, Hunt PR, Sidwa TJ.To determine whether postexposure rabies prophylaxis (PEP) in domestic animals, as mandated in Texas, has continued to be effective and to evaluate preexposure or postexposure vaccination failures from 2000 through 2009. Methods: Retrospective case series. Methods: 1,014 unvaccinated domestic animals (769 dogs, 126 cats, 72 horses, 39 cattle, 3 sheep, 4 goats, and 1 llama) that received PEP and 12 vaccinated domestic animals (7 dogs and 5 cats) with possible failure of protection. Methods: Zoonotic incident reports from 2000 through 2009 were reviewed for information regarding unvaccinated dom...
Welfare and health of horses transported for slaughter within the European Union Part 1: Methodology and descriptive data.
Equine veterinary journal    December 15, 2010   Volume 43, Issue 1 78-87 doi: 10.1111/j.2042-3306.2010.00124.x
Marlin D, Kettlewell P, Parkin T, Kennedy M, Broom D, Wood J.Anecdotal evidence collected by a variety of organisations has highlighted poor welfare in horses transported long distances to slaughter within the European Union. Objective: To investigate welfare of horses being transported long distances within the EU to slaughter. Methods: Data on transported horses were recorded at 2 assembly centres in Romania and at 4 abattoirs in Italy over an 8 month period in 2008. Results: A total of 1519 horses in 64 separate shipments were observed in Romania prior to transport of which 212 horses were deemed unfit for transport and only 3 shipments (5%) complied...
PRINS detection of 18S rDNA in pig, red fox and Chinese raccoon dog, and centromere DNA in horse.
Hereditas    December 15, 2010   Volume 147, Issue 6 320-324 doi: 10.1111/j.1601-5223.2010.02201.x
Wnuk M, Oklejewicz B, Lewinska A, Zabek T, Bartosz G, Slota E, Bugno-Poniewierska M.The fluorescence in situ hybridization (FISH) technique is widely used in animal cytogenetics. Contrary to FISH procedure, primed in situ DNA synthesis (PRINS) does not require the DNA probe preparation (design, synthesis, gel purification of PCR products and labeling). The PRINS method with primers used as 'DNA probes' is both PCR-sensitive and allows for chromosomal localization of DNA sequences. Here, we show the application of PRINS reaction with one unlabeled oligonucleotide pair to identify 18S rDNA loci in three different animal species: domestic pig (Sus scrofa), red fox (Vulpes vulpes...
Morphometric and ultrastructural features of the mare oviduct epithelium during oestrus.
Theriogenology    December 15, 2010   Volume 75, Issue 4 671-678 doi: 10.1016/j.theriogenology.2010.10.007
Desantis S, Zizza S, Accogli G, Acone F, Rossi R, Resta L.Morphometric, scanning electron microscopy (SEM) and transmission electron microscopy (TEM) investigations have displayed regional differences in the mare oviductal epithelium. The entire mucosa of the oviduct was lined with a pseudostratified epithelium, which consisted of two distinct cell types, ciliated and non-ciliated. Ciliated cells were predominant in the three different segments of the oviduct and their percentage increased from fimbriae to ampulla and significantly decreased in the isthmus. SEM revealed in the infundibulum finger-like mucosal folds, some of them interconnected, in th...
Expansion of mesenchymal stem cells on fibrinogen-rich protein surfaces derived from blood plasma.
Journal of tissue engineering and regenerative medicine    December 10, 2010   Volume 5, Issue 8 600-611 doi: 10.1002/term.352
Kisiday JD, Hale BW, Almodovar JL, Lee CM, Kipper MJ, Wayne McIlwraith C, Frisbie DD.Mesenchymal stem cells (MSCs) are present in low density in bone marrow and culture expansion is necessary to obtain sufficient numbers for many proposed therapies. Researchers have characterized MSC growth on tissue culture plastic (TCP), although few studies have explored proliferation on other growth substrates. Using adult equine MSCs, we evaluated proliferation on fibrinogen-rich precipitate (FRP) surfaces created from blood plasma. When seeded at 1 × 10(4) cells/cm(2) and passaged five times over 10 days, MSCs on FRP in medium containing fibroblast growth factor 2 (FGF2) resulted in a ...
Effects of season and body condition on appetite, body mass and body composition in ad libitum fed pony mares.
Veterinary journal (London, England : 1997)    December 10, 2010   Volume 190, Issue 3 329-337 doi: 10.1016/j.tvjl.2010.11.009
Dugdale AH, Curtis GC, Cripps PJ, Harris PA, Argo CM.Changes in appetite, body mass (BM), body condition score (BCS), direct (ultrasonographic) and indirect (deuterium oxide dilution technique) measures of body fat were monitored in Welsh Mountain pony mares (n=11, 5-19 years of age) offered ad libitum access to a complete diet (gross energy 16.9±0.07 MJ/kg dry matter) for 12 weeks during summer (n=6; 246±20 kg) and winter (n=5; 219±21 kg). At the outset, each group comprised two thin (BCS 1-3/9), moderate (BCS 4-6/9) and obese (BCS 7-9/9) animals. For ponies that were non-obese at the outset, BM was gained more rapidly (P=0.001) in summer (0...
Methicillin-resistant Staphylococcus aureus in animals.
ILAR journal    December 7, 2010   Volume 51, Issue 3 233-244 doi: 10.1093/ilar.51.3.233
Weese JS.Methicillin-resistant Staphylococcus aureus (MRSA) is a critically important human pathogen that is also an emerging concern in veterinary medicine and animal agriculture. It is present in a wide range of animal species, including dogs, cats, rabbits, horses, cattle, pigs, poultry, and exotic species, both as a cause of infection and in healthy carriers. Identification of MRSA in various species and in food has led to concerns about the roles of animals, both pets and livestock, in the epidemiology of MRSA infection and colonization in humans. There is evidence of the role of food animals in h...