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Topic:Warmblood Horses

Warmblood horses are a group of middle-weight horse breeds known for their versatility and performance in equestrian sports such as dressage, show jumping, and eventing. They are characterized by a combination of athleticism, temperament, and conformation, which make them suitable for competitive disciplines. Breeds within this group include the Hanoverian, Dutch Warmblood, and Holsteiner, among others. The breeding and selection processes for Warmbloods focus on traits such as movement, trainability, and soundness. This page compiles peer-reviewed research studies and scholarly articles that investigate the genetics, breeding practices, performance traits, and health considerations specific to Warmblood horses.
Plasma atrial natriuretic peptide concentration in warmblood horses with heart valve regurgitations.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    November 26, 2007   Volume 9, Issue 2 99-101 doi: 10.1016/j.jvc.2007.10.003
Gehlen H, Sundermann T, Rohn K, Stadler P.This study measured plasma atrial natriuretic peptide (ANP) concentration in horses with heart valve regurgitations (HVR) with and without atrial and ventricular dilatation. Background: In humans and small animals, plasma ANP concentration is increased in heart disease and correlates with the severity of clinical signs and heart enlargement. Methods: Ten healthy horses (control) and 36 horses with HVR were evaluated by auscultation, electrocardiography, echocardiography, and determination of plasma ANP. Results: Control horses demonstrated mean plasma ANP concentration of 21+/-5.4 pg/mL. Of th...
Allelic heterogeneity at the equine KIT locus in dominant white (W) horses.
PLoS genetics    November 14, 2007   Volume 3, Issue 11 e195 doi: 10.1371/journal.pgen.0030195
Haase B, Brooks SA, Schlumbaum A, Azor PJ, Bailey E, Alaeddine F, Mevissen M, Burger D, Poncet PA, Rieder S, Leeb T.White coat color has been a highly valued trait in horses for at least 2,000 years. Dominant white (W) is one of several known depigmentation phenotypes in horses. It shows considerable phenotypic variation, ranging from approximately 50% depigmented areas up to a completely white coat. In the horse, the four depigmentation phenotypes roan, sabino, tobiano, and dominant white were independently mapped to a chromosomal region on ECA 3 harboring the KIT gene. KIT plays an important role in melanoblast survival during embryonic development. We determined the sequence and genomic organization of t...
Effect of show jumping training on the development of locomotory muscle in young horses.
American journal of veterinary research    November 3, 2007   Volume 68, Issue 11 1232-1238 doi: 10.2460/ajvr.68.11.1232
Rietbroek NJ, Dingboom EG, Joosten BJ, Eizema K, Everts ME.To investigate whether training for show jumping that is commenced early after birth affects the characteristics of equine locomotory muscle. Methods: 19 Dutch Warmblood horses. Methods: Horses were assigned to a trained or not trained (control) group. After weaning, training (free jumping [2 d/wk] that was alternated with a 20-minute period of exercise in a mechanical rotating walker [3 d/wk]) was started and continued until horses were 3 years old. Fiber type composition (determined from myosin heavy chain [MyHC] content), fiber area, diffusion index (area supplied by 1 capillary), citrate s...
Immunohistochemical detection of matrix metalloproteinase-1 in the periodontal ligament of equine cheek teeth.
Tissue & cell    October 29, 2007   Volume 39, Issue 6 369-376 doi: 10.1016/j.tice.2007.07.005
Warhonowicz M, Staszyk C, Gasse H.The hypsodont equine cheek tooth erupts continuously throughout life. The collagen fibers of the periodontal ligament (PDL) have to remodel constantly to allow the tooth to move in an occlusal direction. Remodeling of the collagen fiber bundles needs to be well-coordinated in order to maintain functional tooth support. The aim of this study was to examine the role of matrix metalloproteinase-1 (MMP-1) in the collagen remodeling of the equine PDL under physiological conditions. Specimens containing the PDL interposed between the dental cementum and the alveolar bone were taken from nine Warmblo...
Antibodies to elastin peptides in sera of Warmblood horses at different ages.
Equine veterinary journal    October 4, 2007   Volume 39, Issue 5 414-416 doi: 10.2746/042516407x204573
van Brantegem L, de Cock HE, Affolter VK, Duchateau L, Govaere J, Ferraro GL, Ducatelle R.Early diagnosis and monitoring progression of chronic diseases in elastin-rich tissues, such as chronic progressive lymphoedema in draught horses and chronic obstructive pulmonary disease (COPD) is still a real challenge in the horse. Use of an enzyme-linked immunosorbent assay (ELISA) to detect anti-elastin antibody (AEAb) levels might be useful to assess the status of such diseases. Baseline levels, representing physiological breakdown of elastin in normal horses, are not available at present. Objective: Levels of AEAb in healthy horses are generally low and follow the same age-related patte...
Sequence analysis of the equine SLC26A2 gene locus on chromosome 14q15–>q21.
Cytogenetic and genome research    September 29, 2007   Volume 118, Issue 1 55-62 doi: 10.1159/000106441
Hansen M, Knorr C, Hall AJ, Broad TE, Brenig B.The solute carrier family 26, member 2 (SLC26A2) gene belongs to a family of multifunctional anion exchangers. Mutations in the human SLC26A2 gene are associated with autosomal recessively inherited chondrodysplasias. Hence, we postulate that the equine SLC26A2 could be a candidate gene for conformational traits in horses. An equine BAC clone harboring the SLC26A2 gene was isolated. The complete 142,625 bp insert sequence of this clone was determined by transposon sequencing. Together with the SLC26A2 gene the BAC clone contains four genes, i.e. the macrophage colony stimulating factor 1 recep...
Focal increased radiopharmaceutical uptake in the dorsoproximal diaphyseal region of the equine proximal phalanx. Bailey RE, Dyson SJ, Parkin TD.The aims of this study were to establish the frequency of occurrence, intensity and symmetry of focal increased radiopharmaceutical uptake in the dorsoproximal aspect of the diaphysis of the proximal phalanx; to determine if this focal increased radiopharmaceutical uptake was related to age, height, gender, breed, bodyweight, or discipline of the horse, and if there was any relationship with lameness. Scintigraphic images from 690 horses were analyzed subjectively and objectively. Age, breed, discipline, height, weight, gender, and lame limb(s) or reasons for presentation were recorded for all...
Genome-wide search for markers associated with osteochondrosis in Hanoverian warmblood horses.
Mammalian genome : official journal of the International Mammalian Genome Society    September 29, 2007   Volume 18, Issue 10 739-747 doi: 10.1007/s00335-007-9058-9
Dierks C, Löhring K, Lampe V, Wittwer C, Drögemüller C, Distl O.A genome-wide scan was performed to detect quantitative trait loci (QTLs) for osteochondrosis (OC) and osteochondrosis dissecans (OCD) in horses. The marker set comprised 260 microsatellites. We collected data from 211 Hanoverian warmblood horses consisting of 14 paternal half-sib families. Traits used were OC (fetlock and/or hock joints affected), OCD (fetlock and/or hock joints affected), fetlock OC, fetlock OCD, hock OC, and hock OCD. The first genome scan included 172 microsatellite markers. In a second step 88 additional markers were chosen to refine putative QTLs found in the first scan....
Comparative examination of percussional and echocardiographic determination of the cardiac dullness area in healthy horses.
Acta veterinaria Hungarica    September 18, 2007   Volume 55, Issue 3 277-286 doi: 10.1556/AVet.55.2007.3.1
Bakos Z, Vörös K.Since percussion started to be a method forgotten and not trusted by many practitioners, the aim of the study was to demonstrate whether this procedure could deliver exact data if done accurately and by a practised examiner. The trial presented here included 31 healthy warm-blooded horses. Percussion of the area of cardiac dullness and then echocardiographic imaging of the same region were performed. To obtain the relevant measurement points, the 4th and 5th intercostal spaces (ICS) were used on the left and the 4th ICS on the right side. On the left side, the dorsal border of cardiac dullness...
Removal of a sialolith by an intraoral surgical approach in a warmblood gelding.
The Veterinary record    September 11, 2007   Volume 161, Issue 10 354-356 doi: 10.1136/vr.161.10.354
Haralambus RM, Simhofer H, Zappe H.No abstract available
Confirmed and presumptive cervical vertebral compressive myelopathy in older horses: a retrospective study (1992-2004).
Journal of veterinary internal medicine    August 22, 2007   Volume 21, Issue 4 812-819 doi: 10.1892/0891-6640(2007)21[812:capcvc]2.0.co;2
Levine JM, Adam E, MacKay RJ, Walker MA, Frederick JD, Cohen ND.Cervical vertebral compressive myelopathy (CVCM) is a common cause of myelopathy in horses aged 6 months to 4 years. Little information is available regarding the types of lesions, treatment, and outcomes in horses with CVCM that are > or =4 years old. Methods: Twenty-two affected horses (10 with a confirmed diagnosis of CVCM and 12 presumptive cases) and 210 contemporaneous control horses. Methods: Horses > or =4 years old that were diagnosed with CVCM between January 1992 and January 2004 were identified from medical records at Texas A&M University and the University of Florida. Data analyze...
Veterinary-care events and costs over a 5-year follow-up period for warmblooded riding horses with or without previously recorded locomotor problems in Sweden.
Preventive veterinary medicine    August 6, 2007   Volume 83, Issue 2 130-143 doi: 10.1016/j.prevetmed.2007.06.008
Egenvall A, Bonnett B, Wattle O, Emanuelson U.Our objective was to determine the amount, type and cost of veterinary care during a 5-year follow-up period, in Swedish warmblooded riding horses with and without locomotor problems as recorded in 1997. The study population comprised horses with complete insurance both for veterinary care and life during 1997. The horses were followed from the beginning of January 1998 to the end of December 2002. The exposed cohort was composed of 1558 horses that had experienced >or=1 veterinary-care event because of locomotor problems in 1997 (LP-cohort). The exposure-negative (LN) cohort was composed of 1...
Thoracic percussion to determine the caudal lung border in healthy horses.
Journal of veterinary internal medicine    June 8, 2007   Volume 21, Issue 3 504-507 
Bakos Z, Vörös K.The application of equine thoracic percussion has been ignored because of the availability of modern imaging techniques. Ultrasonography is a reliable tool in determining the caudal lung border of horses. The aim of the study was to compare percussion with ultrasonography to determine lung borders in horses. Objective: That thoracic percussion can detect the caudal lung border and that its accuracy is comparable with thoracic ultrasonography. Methods: Fifteen randomly chosen, healthy, Warmblood horses. Methods: The caudal lung border was detected by percussion and ultrasonography at the end of...
Genome-wide search for microsatellite markers associated with radiologic alterations in the navicular bone of Hanoverian warmblood horses.
Mammalian genome : official journal of the International Mammalian Genome Society    June 6, 2007   Volume 18, Issue 5 373-381 doi: 10.1007/s00335-007-9021-9
Diesterbeck US, Hertsch B, Distl O.The aim of this study was to identify quantitative trait loci (QTLs) for pathologic changes in the navicular bone in Hanoverian warmblood horses. Seventeen paternal half-sib groups comprising 192 individuals were analyzed in a whole-genome scan. These families included 144 progeny and grandchildren, which were randomly chosen from the Hanoverian warmblood. Three different traits were considered: deformed canales sesamoidales and radiographic changes in the contour and in the structure of the navicular bone. The genome scan included in total 214 highly polymorphic microsatellite markers. The pu...
The effect of plain, eggbar and 6 degrees-wedge shoes on the distribution of pressure under the hoof of horses at the walk.
New Zealand veterinary journal    May 31, 2007   Volume 55, Issue 3 120-124 doi: 10.1080/00480169.2007.36753
Rogers CW, Back W.To quantify the effect of plain, wedged and eggbar shoes on the distribution of pressure under the hoof of horses at the walk, at selected areas of interest (AOI), to find scientific evidence for the perceived efficacy of these shoes in the treatment of palmar heel pain. Methods: Six clinically sound adult Warmblood mares weighing 551 (SD 25) kg were shod (forelegs) with either plain, eggbar or 6 degrees-wedge shoes using a latin-square experimental design. All horses were shod by the same farrier, and each balanced and aligned for its individual conformation. Data were collected on three walk...
A region on equine chromosome 13 is linked to recurrent airway obstruction in horses.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 236-241 doi: 10.2746/042516407x171110
Jost U, Klukowska-Rötzler J, Dolf G, Swinburne JE, Ramseyer A, Bugno M, Burger D, Blott S, Gerber V.REASONS FOR STUDY: Equine recurrent airway obstruction (RAO) is probably dependent on a complex interaction of genetic and environmental factors and shares many characteristic features with human asthma. Interleukin 4 receptor a chain (IL4RA) is a candidate gene because of its role in the development of human asthma, confirmation of this association is therefore required. Methods: The equine BAC clone containing the IL4RA gene was localised to ECA13q13 by the FISH method. Microsatellite markers in this region were investigated for possible association and linkage with RAO in 2 large Warmblood ...
Validation of vertical ground reaction forces on individual limbs calculated from kinematics of horse locomotion.
The Journal of experimental biology    May 23, 2007   Volume 210, Issue Pt 11 1885-1896 doi: 10.1242/jeb.02774
Bobbert MF, Gómez Alvarez CB, van Weeren PR, Roepstorff L, Weishaupt MA.The purpose of this study was to determine whether individual limb forces could be calculated accurately from kinematics of trotting and walking horses. We collected kinematic data and measured vertical ground reaction forces on the individual limbs of seven Warmblood dressage horses, trotting at 3.4 m s(-1) and walking at 1.6 m s(-1) on a treadmill. First, using a segmental model, we calculated from kinematics the total ground reaction force vector and its moment arm relative to each of the hoofs. Second, for phases in which the body was supported by only two limbs, we calculated the individu...
[Prevalence of hereditary diseases in three-year-old Swiss Warmblood horses].
Schweizer Archiv fur Tierheilkunde    April 28, 2007   Volume 149, Issue 4 161-171 doi: 10.1024/0036-7281.149.4.161
Studer S, Gerber V, Straub R, Brehm W, Gaillard C, Lüth A, Burger D.The objective of this study was to investigate clinical signs indicating hereditary diseases like equine sarcoid, osteochondrosis (OC) and the idiopathic laryngeal hemiplegia (ILH), and to demonstrate relationships between environment, feeding habits and conformation ("exterieur" evaluation) of the horses. For this purpose, we analyzed veterinary examinations of 403 stallions at the approvals since 1994 examined 493 three-year-old Swiss Warmblood horses, which were shown at the Swiss-Field-Tests in 2005. With the help of the owners a questionnaire on health, environment and feeding habits of t...
A polymorphism within the equine CRISP3 gene is associated with stallion fertility in Hanoverian warmblood horses.
Animal genetics    April 13, 2007   Volume 38, Issue 3 259-264 doi: 10.1111/j.1365-2052.2007.01594.x
Hamann H, Jude R, Sieme H, Mertens U, Töpfer-Petersen E, Distl O, Leeb T.Fertility of stallions is of high economic importance, especially for large breeding organisations and studs. Breeding schemes with respect to fertility traits and selection of stallions at an early stage may be improved by including molecular genetic markers associated with traits. The genes coding for equine cysteine-rich secretory proteins (CRISPs) are promising candidate genes because previous studies have shown that CRISPs play a role in the fertilising ability of male animals. We have previously characterised the three equine CRISP genes and identified a non-synonymous polymorphism in th...
Effects of draw reins on limb kinematics.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 452-456 doi: 10.1111/j.2042-3306.2006.tb05586.x
Byström A, Roepstorff L, Johnston C.No data exist on the GRF-kinematics relation due to changes caused by equestrian interventions. Objective: Through the judicious use of draw reins the rider can influence the kinematics of the horse to meet stated goals of dressage training. Relating the results to previously published kinetic data of the same experiment implies a possible relationship between kinetics and kinematics. Methods: The kinematics of 8 sound Swedish Warmblood horses were measured whilst the horses were being ridden with and without draw reins. Three conditions were evaluated: 1) draw reins only (DR), 2) combination ...
Raising heels of hind hooves changes the equine coffin, fetlock and hock joint angle: a kinematic evaluation on the treadmill at walk and trot.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 427-430 doi: 10.1111/j.2042-3306.2006.tb05581.x
Peham C, Girtler D, Kicker C, Licka T.Raised heels are commonly recommended for various equine orthopaedic conditions. However, the simultaneous effect of raised heels on the different joint angles of the equine hindlimb throughout the motion cycle has not been previously evaluated. Objective: To document the simultaneous effect of raised heels on the joint angles of the equine hindlimb coffin, fetlock and hock joints. Methods: Eight sound, adult, Warmblood horses were evaluated barefoot and with a heel wedge of 8 or 16 degrees, walking and trotting on a horizontal treadmill. Markers placed on the dorsal and cranial aspect of the ...
Prevalence of polysaccharide storage myopathy in horses with neuromuscular disorders.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 340-344 doi: 10.1111/j.2042-3306.2006.tb05565.x
McCue ME, Ribeiro WP, Valberg SJ.Controversy exists as to the prevalence of polysaccharide storage myopathy (PSSM) in breeds of horses and its impact on performance. Objective: To determine 1) the prevalence of PSSM in horses that presented with a neuromuscular disorder, as well as breed, sex and age distributions and clinical signs 2) effect of diagnostic criteria on prevalence, breed distribution and age of horses diagnosed with PSSM. Methods: Fresh frozen biopsies (n = 1426) submitted to the Neuromuscular Diagnostic Laboratory at the University of Minnesota were searched to identify horses diagnosed with PSSM. Horses with ...
Genotypic characterization of VapA positive Rhodococcus equi in foals with pulmonary affection and their soil environment on a warmblood horse breeding farm in Germany.
Research in veterinary science    March 13, 2007   Volume 83, Issue 3 311-317 doi: 10.1016/j.rvsc.2007.01.009
Venner M, Meyer-Hamme B, Verspohl J, Hatori F, Shimizu N, Sasaki Y, Kakuda T, Tsubaki S, Takai S.Pulsotypes of VapA positive Rhodococcus equi isolated from foals and soil on a farm in Germany were characterized on the basis of nasal and tracheal samples simultaneously collected in 2003 from 217 foals with sonographic evidence of pneumonia or pulmonary abscesses. Of the 217 double samples, R. equi was isolated in 118 (54%) of the tracheal samples and in 52 of the nasal swab samples (24%) (P<0.001). Furthermore, 37 and 55 isolates were also randomly selected from nasal swabs and the tracheal samples, respectively, and further processed to determine the presence of VapA by colony blot enz...
Effects of genetic and environmental factors on chronic lower airway disease in horses.
Journal of veterinary internal medicine    March 7, 2007   Volume 21, Issue 1 149-156 doi: 10.1892/0891-6640(2007)21[149:eogaef]2.0.co;2
Ramseyer A, Gaillard C, Burger D, Straub R, Jost U, Boog C, Marti E, Gerber V.Environment and genetics influence the manifestation of recurrent airway obstruction (RAO), but the associations of specific factors with mild, moderate, and severe clinical signs are unknown. Objective: We hypothesized that sire, feed, bedding, time outdoors, sex, and age are associated with clinical manifestations of mild, moderate, and severe lower airway disease. Methods: Direct offspring of 2 RAO-affected Warmblood stallions (F1S1, n = 172; F1S2, n = 135); maternal half-siblings of F1S1 (mHSS1, n = 66); and an age-matched, randomly chosen control group (CG, n = 33). Methods: A standardize...
Pharyngeal neuromuscular dysfunction associated with bilateral guttural pouch tympany in a foal.
The Canadian veterinary journal = La revue veterinaire canadienne    March 6, 2007   Volume 48, Issue 2 192-194 
Bell C.A 2-month-old warmblood filly was presented for a 1-week history of a large, nonpainful, fluctuant swelling of the parotid and laryngeal area. Bilateral guttural pouch tympany was diagnosed. Surgical correction resolved the guttural pouch tympany; however, postoperative pharyngeal neuromuscular dysfunction developed. Dysfonction pharyngée neuromusculaire associée à un tympanisme bilatéral des poches gutturales chez un poulain. Une pouliche de race Warmblood a été présentée pour examen d’une enflure marquée non-douloureuse et fluctuante, localisée dans la région laryngée et paroti...
Use of a parathyroid hormone peptide (PTH(1-34))-enriched fibrin hydrogel for the treatment of a subchondral cystic lesion in the proximal interphalangeal joint of a warmblood filly.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    February 20, 2007   Volume 54, Issue 2 107-112 doi: 10.1111/j.1439-0442.2007.00890.x
Fuerst A, Derungs S, von Rechenberg B, Auer JA, Schense J, Watson J.To describe the treatment of a subchondral bone cyst in the proximal phalanx with parathyroid hormone peptide-enriched fibrin hydrogel in a warmblood filly. The cyst was localized with computer-assisted orthopaedic surgery, then curetted and finally filled with parathyroid hormone fragment peptide 1-34 (PTH(1-34)) covalently attached to a fibrin hydrogel. The cyst healed quickly without any complications. This result supports the hypothesis that PTH(1-34) delivered locally in a fibrin hydrogel may improve the postoperative prognosis of surgical management of subchondral bone cysts in horses. S...
Developmental aspects of distal limb conformation in the horse: the potential consequences of uneven feet in foals.
Equine veterinary journal    January 19, 2007   Volume 38, Issue 7 652-656 doi: 10.2746/042516406x159089
Kroekenstoel AM, van Heel MC, van Weeren PR, Back W.Distal limb conformation is generally accepted to be an important item with respect to performance and soundness in mature horses, but little is known about the developmental aspects. Objective: To gain insight into the development of distal limb conformation and to assess the possible consequences of uneven feet in foals. Methods: Conformation of the distal front limbs of 23 Warmblood foals was scored visually and measured using radiographs, at ages 27 and 55 weeks. At the same ages, pressure measurements were made under both front feet. Results: At both ages the hoof-pastern axis was broken-...
Genetic correlations between performance traits and radiographic findings in the limbs of German Warmblood riding horses.
Journal of animal science    December 21, 2006   Volume 85, Issue 1 31-41 doi: 10.2527/jas.2005-605
Stock KF, Distl O.Results of mare performance tests in the field (MPT-F) of 10,949 mares, mare performance tests at station (MPT-S) of 1,712 mares, and inspections of horses intended for sale at riding horse auctions (AU) of 4,772 horses were used to investigate genetic correlations between corresponding performance traits. Mare performance tests were held in 1995 to 2004 and auction inspections in 1999 to 2004. Scores on a scale from 0 to 10 were given for gaits under rider (walk, trot, canter), rideability (evaluated by judging commission and test rider), free-jumping (ability, style, total), and character. R...
Magnetic resonance imaging, ultrasonography and histology of the suspensory ligament origin: a comparative study of normal anatomy of warmblood horses.
Equine veterinary journal    November 28, 2006   Volume 38, Issue 6 508-516 doi: 10.2746/042516406x156109
Bischofberger AS, Konar M, Ohlerth S, Geyer H, Lang J, Ueltschi G, Lischer CJ.The diagnosis of lameness caused by proximal metacarpal and metatarsal pain can be challenging. Magnetic resonance imaging (MRI) offers the possibility for further diagnosis but there have been no studies on the normal MRI appearance of the origin of the suspensory ligament (OSL) in conjunction with ultrasonography and histology. Objective: To describe the MRI appearance of the OSL in fore- and hindlimbs of sound horses and compare it to the ultrasonographic and histological appearance. The findings can be used as reference values to recognise pathology in the OSL. Methods: The OSL in the fore...
Genetic correlations between conformation traits and radiographic findings in the limbs of German Warmblood riding horses.
Genetics, selection, evolution : GSE    November 28, 2006   Volume 38, Issue 6 657-671 doi: 10.1186/1297-9686-38-6-657
Stock KF, Distl O.Studbook inspection (SBI) data of 20 768 German Warmblood mares and radiography results (RR) data of 5102 Hanoverian Warmblood horses were used for genetic correlation analyses. The scores on a scale from 0 to 10 were given for conformation and basic quality of gaits, resulting in 14 SBI traits which were used for the correlation analyses. The radiographic findings considered included osseous fragments in fetlock (OFF) and hock joints (OFH), deforming arthropathy in hock joints (DAH) and distinct radiographic findings in the navicular bones (DNB) which were analyzed as binary traits, and radio...
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