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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Technical Note: The use of iSperm technology for on-farm measurement of equine sperm motility and concentration.
Translational animal science    August 15, 2019   Volume 3, Issue 4 1513-1520 doi: 10.1093/tas/txz115
Moraes CR, Runcan EE, Blawut B, Coutinho da Silva MA.The iSperm is a newly released semen analysis tool from Aidmics Biotechnology Co. LTD, which allows an iPad Mini to be transformed into a handheld microscope with objective semen analysis software for equine available through the Apple Store (version 4.5.2). The aim of this study was to compare iSperm values for sperm motility and sperm concentration to current acceptable methods for semen analysis and to determine the agreement with these methods using statistical methods. Two ejaculates from each of five Standardbred stallions were used to compare sperm motility (computer-assisted semen anal...
[Equestrian related injuries and pathologies].
Revue medicale suisse    August 15, 2019   Volume 15, Issue 658 1383-1386 
Hochart É, Fournier Y.Equestrian sports are widely practiced in Switzerland as hobbies. Horses are imposing and unpredictable. As a result, traumatisms associated with horseback riding are common and cause serious injuries. Cranial traumatisms are among the most frequently encountered injuries and are associated with high rates of hospitalization and mortality. Helmet use decreases the severity of intracranial lesions. Close contact with horses can lead to the development of infectious diseases and respiratory allergies. Although infrequent in Europe, these infections occur sporadically and should be known by gener...
Individual differences in behavior and heart rate variability across the preweaning period in the domestic horse in response to an ecologically relevant stressor.
Physiology & behavior    August 13, 2019   Volume 210 112652 doi: 10.1016/j.physbeh.2019.112652
Pérez Manrique L, Hudson R, Bánszegi O, Szenczi P.The study of individual differences in behavior and physiology has attracted considerable interest among behavioral biologists. Important questions include how early in life such differences emerge and to what extent they remain stable across development. Due to the demanding nature of longitudinal studies, there is still a lack of information on this in mammals, especially in large, long-lived species. Our aim in this study was to look for stable individual differences in behavior and physiology during early development in the domestic horse and for correlations between the two parameters. We...
Application of a laparoscopic technique for vasectomy in standing horses.
The Veterinary record    August 13, 2019   Volume 185, Issue 11 345 doi: 10.1136/vr.105396
Vitoria A, Romero A, Fuente S, Barrachina L, Vazquez FJ.This report describes a technique for standing laparoscopic vasectomy in stallions through a prospective descriptive study. A preliminary study was carried out with two experimental intact male horses and subsequently the procedure was performed in two clinical cases. These horse owners want to keep their animals in the most possible natural way, preserving its stallion behaviour in a herd without generating offspring. The horses were sedated and restrained in stocks and laparoscopic vasectomy was performed using three portal sites in both paralumbar fossae recording surgical times. A 4-cm seg...
Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species.
Nature communications    August 13, 2019   Volume 10, Issue 1 3642 doi: 10.1038/s41467-019-11639-2
de la Rosa G, Olvera F, Archundia IG, Lomonte B, Alagón A, Corzo G.Antivenoms are fundamental in the therapy for snakebites. In elapid venoms, there are toxins, e.g. short-chain α-neurotoxins, which are quite abundant, highly toxic, and consequently play a major role in envenomation processes. The core problem is that such α-neurotoxins are weakly immunogenic, and many current elapid antivenoms show low reactivity towards them. We have previously developed a recombinant consensus short-chain α-neurotoxin (ScNtx) based on sequences from the most lethal elapid venoms from America, Africa, Asia, and Oceania. Here we report that an antivenom generated by immu...
Systematic analysis to assess the scientific validity of the international residue limits for caffeine and theophylline in horse-racing.
The Veterinary record    August 13, 2019   Volume 185, Issue 8 230 doi: 10.1136/vr.105404
Hertzsch R, Richter A.Based on their performance-enhancing potential, caffeine and theophylline are prohibited substances in equine sports. Residues in horses can be caused by wilful application or by unintended uptake of contaminated feed. The International Federation of Horseracing Authorities recently introduced international residue limits (IRLs) to facilitate the discrimination between pharmacological relevant and irrelevant concentrations in doping samples. The objective of this study was to investigate the scientific validity of these IRLs. A systematic analysis was performed to assess the IRLs by different ...
Gasterophilus flavipes (Oestridae: Gasterophilinae): A horse stomach bot fly brought back from oblivion with morphological and molecular evidence.
PloS one    August 12, 2019   Volume 14, Issue 8 e0220820 doi: 10.1371/journal.pone.0220820
Li XY, Pape T, Zhang D.Species of Gasterophilus Leach are obligate parasites in domestic and wild equids and responsible for cosmopolitan gasterophilosis. Although with only eight species known so far, they have received considerable attention because of their significant veterinary and economic importance. Surprisingly, we found that G. flavipes (Olivier) is a valid species based on morphological characters from male, female and the egg, after spending half a century as a synonym of G. haemorrhoidalis (Linnaeus). In the present study, G. flavipes, G. haemorrhoidalis and G. inermis (Brauer), which are the three clos...
A comparative multi-site and whole-body assessment of fascia in the horse and dog: a detailed histological investigation.
Journal of anatomy    August 11, 2019   Volume 235, Issue 6 1065-1077 doi: 10.1111/joa.13064
Ahmed W, Kulikowska M, Ahlmann T, Berg LC, Harrison AP, Elbrønd VS.Fascia in the veterinary sciences is drawing attention, such that physiotherapists and animal practitioners are now applying techniques based on the concept of fascia studies in humans. A comprehensive study of fascia is therefore needed in animals to understand the arrangement of the fascial layers in an unguligrade horse and a digitigrade dog. This study has examined the difference between the horse and the dog fascia at specific regions, in terms of histology, and has compared it with the human model. Histological examinations show that in general the fascia tissue of the horse exhibits a t...
Deslorelin and naltrexone stimulate follicular development in mares during autumn transition and early anestrus.
The Canadian veterinary journal = La revue veterinaire canadienne    August 9, 2019   Volume 60, Issue 8 855-858 
Kwong GPS, Klein C.Horses are long-day breeders and commence ovarian follicular activity during the spring. Evidence suggests that there is an endogenous circannual rhythm in mares, and it is uncertain whether hormonal manipulation during or immediately following the fall transition induces follicular development. The current study was designed to test the hypothesis that both deslorelin and naltrexone induce follicular development in late fall transitioning or anestrous mares. Five of six mares treated with deslorelin, and 4 of 6 mares treated with naltrexone, developed a pre-ovulatory-sized follicle and were i...
Horses associate individual human voices with the valence of past interactions: a behavioural and electrophysiological study.
Scientific reports    August 9, 2019   Volume 9, Issue 1 11568 doi: 10.1038/s41598-019-47960-5
Brain lateralization is a phenomenon widely reported in the animal kingdom and sensory laterality has been shown to be an indicator of the appraisal of the stimulus valence by an individual. This can prove a useful tool to investigate how animals perceive intra- or hetero-specific signals. The human-animal relationship provides an interesting framework for testing the impact of the valence of interactions on emotional memories. In the present study, we tested whether horses could associate individual human voices with past positive or negative experiences. Both behavioural and electroencephalo...
Genomic Regions Associated with IgE Levels against Culicoides spp. Antigens in Three Horse Breeds.
Genes    August 8, 2019   Volume 10, Issue 8 doi: 10.3390/genes10080597
François L, Hoskens H, Velie BD, Stinckens A, Tinel S, Lamberigts C, Peeters L, Savelkoul HFJ, Tijhaar E, Lindgren G, Janssens S, Ducro BJ, Buys N....Insect bite hypersensitivity (IBH), which is a cutaneous allergic reaction to antigens from Culicoides spp., is the most prevalent skin disorder in horses. Misdiagnosis is possible, as IBH is usually diagnosed based on clinical signs. Our study is the first to employ IgE levels against several recombinant Culicoides spp. allergens as an objective, independent, and quantitative phenotype to improve the power to detect genetic variants that underlie IBH. Genotypes of 200 Shetland ponies, 127 Icelandic horses, and 223 Belgian Warmblood horses were analyzed while using a mixed model approach. No s...
Factors associated with rehoming and time until rehoming for horses listed with an equine charity.
The Veterinary record    August 7, 2019   Volume 185, Issue 12 373 doi: 10.1136/vr.105398
Rosanowski S, Verheyen K.The number of unwanted horses in the UK has increased in recent years. It is therefore important to identify factors that indicate whether a horse can be rehomed and how long it takes to be rehomed. Data from 1 January 2013 until 30 March 2014 were extracted from an equine rehoming charity's database. Exposure variables were examined using multivariable logistic and Cox regression. In total, 791 horses were included in the study and 410 (51.8%) were rehomed during the study period. Median time until rehomed was 39 days (IQR 24-75). Horses whose owner was prepared to transfer ownership were nea...
Description of Placement Procedures for Common Methods Used in Equine Emergency Rescue Using a Simplified Loops System.
Animals : an open access journal from MDPI    August 5, 2019   Volume 9, Issue 8 529 doi: 10.3390/ani9080529
Madigan J, Costa L, Nieves S, Horgan M, Weberg K, Aleman M.Entrapped, stranded and recumbent equids often require emergency rescue. The success of the rescue is often affected by secondary injuries from struggling of the horse to rise and from injury secondary to attempted rescue by pulling on the head or limbs of the equid. Therefore, having ready access to simplified rescue equipment which can be easily applied would be desirable. The devices currently available for these manipulations are not always readily available at the site of an incident. Here, we describe and illustrate the step-by-step use of a Loops System consisting of 183 cm round slings...
A new method for quantifying causative and diagnostic markers of methylenecyclopropylglycine poisoning.
Toxicology reports    August 5, 2019   Volume 6 803-808 doi: 10.1016/j.toxrep.2019.08.002
Sander J, Terhardt M, Sander S, Aboling S, Janzen N.Up to now quantification of hypoglycin A in serum and urine in the range of nmols to μmols per liter plus the measurement of accumulated acyl conjugates have been used for the diagnosis of poisoning by fruits or seeds of in humans and animals. A second poison, methylenecyclopropylglycine, however, is known to occur in this material. The objective of our study was to develop and evaluate a method for the quantification of this compound suitable for test materials obtained from animals and man. Methods: Methylenecyclopropylglycine was extracted from serum and urine of a volunteer by a methanoli...
Evaluation of the effectiveness of programs combating the invasions of strongyles (Strongylidae) in horses in selected stables of Western Pomerania.
Annals of parasitology    August 4, 2019   Volume 65, Issue 2 125-128 doi: 10.17420/ap6502.191
Beata Byczkowska , Bogumiła Pilarczyk , Agnieszka Tomza-Marciniak .The emergence of drug resistance among parasites is a side effect of the common use of chemotherapeutic agents in horses. Combating parasites typically involves routine deworming treatments twice a year (before and after the grazing season). However, in grazing farming this treatment may be insufficient. The aim of the study was to evaluate the effectiveness of programs to combat the invasion of strongyles (Strongylidae) in horses in the selected stables of Western Pomerania. Coprological examination was conducted in 85 horses from three stables located in Western Pomerania. Horses from all th...
Genetics of equine metabolic syndrome.
The Veterinary record    August 3, 2019   Volume 185, Issue 5 148 doi: 10.1136/vr.l4725
Rodríguez-Sanz CE, Sevane N, Dunner S.No abstract available
Clinical insights: Equine anaesthesia and analgesia.
Equine veterinary journal    August 3, 2019   Volume 51, Issue 5 563-564 doi: 10.1111/evj.13147
Southwood L.No abstract available
Beyond steroids and bronchodilators – investigating additional therapies for horses with severe equine asthma.
The Veterinary record    August 3, 2019   Volume 185, Issue 5 140-142 doi: 10.1136/vr.l4935
Montgomery JB.No abstract available
pH-dependent effects of procaine on equine gamete activation†.
Biology of reproduction    August 3, 2019   Volume 101, Issue 5 1056-1074 doi: 10.1093/biolre/ioz131
Leemans B, Stout TAE, Soom AV, Gadella BM.Procaine directly triggers pH-dependent cytokinesis in equine oocytes and induces hypermotility in stallion spermatozoa, an important event during capacitation. However, procaine-induced hyperactivated motility is abolished when sperm is washed to remove the procaine prior to sperm-oocyte co-incubation. To understand how procaine exerts its effects, the external Ca2+ and Na+ and weak base activity dependency of procaine-induced hyperactivation in stallion spermatozoa was assessed using computer-assisted sperm analysis. Percoll-washed stallion spermatozoa exposed to Ca2+-depleted (+2 mM EGTA) p...
Ile de Chypre – nobbles, jinks, and the ultrasonic sniper.
Drug testing and analysis    August 2, 2019   Volume 12, Issue 5 651-652 doi: 10.1002/dta.2610
Trevorrow P.In this sensational case, it was alleged that after jinking unexpectedly and throwing its rider, racehorse Ile de Chypre, had been nobbled by an ultrasonic emitter concealed within a pair of binoculars. Ile de Chypre was 4-1 favourite at the King George V Handicap at Ascot on June 16, 1988 and a good distance away from the pack, a clear winner albeit for this alleged act of sensational intervention.
Effect of artificial vagina lubricants on stallion sperm quality.
Theriogenology    August 2, 2019   Volume 139 121-125 doi: 10.1016/j.theriogenology.2019.08.004
Serafini R, Ghosh S, Love CC, Medrano JMR, Teague SR, LaCaze KA, Varner DD.Commercially available vaginal lubricants, typically labeled as non-spermicidal, are used to lubricate equine artificial vaginas prior to semen collection. Improper type or amount of lubricant might affect stallion sperm quality, either after short-time exposure or following cooled storage of extended semen previously exposed to lubricant. The aim of this study was to evaluate stallion sperm quality following exposure to lubricant-containing extender for 1 h (T1h) or 24 h (T24h). Three ejaculates were collected from each of four stallions using a small volume of petrolatum to lubricate a...
Highlights of recent clinically relevant papers.
Equine veterinary education    August 1, 2019   Volume 31, Issue 9 450-451 doi: 10.1111/eve.13155
Wright S.No abstract available
Dysbiosis associated with acute helminth infections in herbivorous youngstock – observations and implications.
Scientific reports    July 31, 2019   Volume 9, Issue 1 11121 doi: 10.1038/s41598-019-47204-6
Peachey LE, Castro C, Molena RA, Jenkins TP, Griffin JL, Cantacessi C.A plethora of data points towards a role of the gastrointestinal (GI) microbiota of neonatal and young vertebrates in supporting the development and regulation of the host immune system. However, knowledge of the impact that infections by GI helminths exert on the developing microbiota of juvenile hosts is, thus far, limited. This study investigates, for the first time, the associations between acute infections by GI helminths and the faecal microbial and metabolic profiles of a cohort of equine youngstock, prior to and following treatment with parasiticides (ivermectin). We observed that high...
Evaluation of a Simplified Loops System for Emergency Rescue Lifting of the Stranded or Recumbent Horse.
Animals : an open access journal from MDPI    July 31, 2019   Volume 9, Issue 8 511 doi: 10.3390/ani9080511
Madigan J, Costa L, Nieves S, Horgan M, Weberg K, Aleman M.Stranded and recumbent equids often require emergency rescue, and a successful rescue often requires vertical lifting of the animal. Currently, the devices used for vertical lifting of equids are not readily available at an incident or urgent situation. The current study describes and evaluates the use of a simple lift device utilizing commercially available, and reasonably priced, equipment. The system, referred to as the Loop Vertical Lift System or Loops System, is basically composed of four round slings placed in such a way that utilizes the skeletal system for support. The study demonstra...
A High Protein Model Alters the Endometrial Transcriptome of Mares.
Genes    July 30, 2019   Volume 10, Issue 8 doi: 10.3390/genes10080576
Boakari YL, Ali HE, Dini P, Loux S, Fernandes CB, Scoggin K, Esteller-Vico A, Lawrence L, Ball B.High blood urea nitrogen (BUN) decreases fertility of several mammals; however, the mechanisms have not been investigated in mares. We developed an experimental model to elevate BUN, with urea and control treatments (7 mares/treatment), in a crossover design. Urea-treatment consisted of a loading dose of urea (0.03 g/kg of body weight (BW)) and urea injections over 6 hours (0.03 g/kg of BW/h). Control mares received the same volume of saline solution. Blood samples were collected to measure BUN. Uterine and vaginal pH were evaluated after the last intravenous infusion, then endometrial biopsie...
Equine cheek tooth extraction: Comparison of outcomes for five extraction methods.
Equine veterinary journal    July 30, 2019   Volume 52, Issue 2 181-186 doi: 10.1111/evj.13150
Caramello V, Zarucco L, Foster D, Boston R, Stefanovski D, Orsini JA.Post-operative complications are reported for all methods of equine cheek tooth extraction but not all methods carry the same risks. An outcome comparison for commonly used methods is needed so that clinicians can make informed treatment decisions. Objective: We conducted a side-by-side comparison of five cheek tooth extraction methods, comparing types and incidence of complications among oral extraction, tooth repulsion (three surgical approaches) and lateral buccotomy techniques. Methods: Retrospective clinical study using hospital medical records. Methods: Medical records of all horses unde...
Comparing and Contrasting Knowledge on Mules and Hinnies as a Tool to Comprehend Their Behavior and Improve Their Welfare.
Animals : an open access journal from MDPI    July 26, 2019   Volume 9, Issue 8 doi: 10.3390/ani9080488
McLean A, Varnum A, Ali A, Heleski C, Navas González FJ.Mules and hinnies are the hybrids between donkeys (Equus asinus) and horses (Equus caballus). For centuries, mankind has used them for agrarian purposes, the military, or recreation. Contrasting literature with behavioral observations, we seek a better behavioral understanding andthus comprehensive solutions for their welfare enhancement. Over the past 6 years, we have assessed physical and behavioral welfare in over 900 mules by surveying owners from Egypt, Peru, Portugal, Spain, Mexico, and the U.S. These mules participated in shows, brick kiln work, cart-pulling, packing, tourism, and cattl...
Effect of body condition on intestinal permeability in horses.
American journal of veterinary research    July 25, 2019   Volume 80, Issue 8 792-798 doi: 10.2460/ajvr.80.8.792
Kopper JJ, Travers JL, Schott HC, Cook VL.To investigate effects of body condition on permeability of intestinal mucosa in horses. Methods: 13 horses (7 obese and 6 lean) from 8 to 15 years of age. Methods: Body condition score was assessed, and an oral sugar test (OST) was performed to evaluate glucose and insulin dynamics. Horses were allowed a 2-week diet acclimation period and were then euthanized. Tissue samples were collected from the jejunum, ileum, cecum, pelvic flexure, right dorsal colon, and rectum. Mucosal permeability was assessed by measuring transepithelial resistance and lipopolysaccharide (LPS) flux across tissue samp...
Hindgut Ciliate Composition of Thoroughbred Mares in Kentucky, USA, and Binary Fission in Polymorphella ampulla.
Zootaxa    July 24, 2019   Volume 4646, Issue 2 zootaxa.4646.2.11 doi: 10.11646/zootaxa.4646.2.11
Gürelli G, Lyons ET, Kesbiç FI.Species composition and distribution of hindgut ciliates were investigated in the feces of 20 thoroughbred mares in Kentucky, USA. Thirty-three species and six morphotypes belonging to 21 genera were identified. The average density of hindgut ciliates in mares was 13.5 ± 13.7 × 104 cells ml-1, whereas mean number of ciliate species per host was 14.4 ± 5.3. Bundleia nana, B. elongata, B. piriformis, Blepharoconus hemiciliatus, Holophryoides ovalis, H. macrotricha, Blepharoprosthium polytrichum, Prorodonopsis coli, Paraisotrichopsis composita, Blepharocorys microcorys, and Ochoterenaia append...
Epithelial-to-mesenchymal transition and keratinocyte differentiation in equine experimental body and limb wounds healing by second intention.
Veterinary dermatology    July 22, 2019   Volume 30, Issue 5 417-e126 doi: 10.1111/vde.12774
Jørgensen E, Pirone A, Jacobsen S, Miragliotta V.The re-epithelialization process in equine wound healing is incompletely described. For epithelial cells to migrate during embryogenesis they undergo epithelial-to-mesenchymal transition (EMT); this phenotypic transition occurs during wound healing in humans and rodents, but it has not been investigated in horses. Objective: To investigate keratinocyte differentiation and EMT in equine experimental excisional limb and body wounds healing by second intention. Methods: Six adult research horses. Methods: Immunohistochemical analysis was used to detect expression of the differentiation markers cy...