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Topic:Animal Health

Animal Health encompasses a broad range of topics focused on maintaining and improving the well-being of equine species. This field addresses various aspects of horse care, including disease prevention, diagnosis, treatment, and management of health conditions. Key areas of interest include equine nutrition, vaccination protocols, parasite control, dental care, and the management of chronic conditions such as laminitis and colic. Additionally, animal health research in horses investigates the impact of exercise and training on physical health, the role of genetics in disease susceptibility, and the development of new therapeutic approaches. This page compiles peer-reviewed research studies and scholarly articles that explore the latest advancements, challenges, and best practices in preserving and enhancing the health of horses.
Veterinary Medical Ethics.
The Canadian veterinary journal = La revue veterinaire canadienne    December 6, 2017   Volume 58, Issue 12 1253-1255 
Rollin BE.No abstract available
Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide-poisoned horses. Fox JH, Porter BF, Easterwood L, Hildenbrand JRV, Hélie P, Smylie J, O'Toole D.Metal phosphides, particularly zinc and aluminum phosphide, occasionally poison horses and other equids following their use as rodenticides and insecticides. Grain-based aluminum phosphide baits are used to control rodents such as prairie dogs. The clinical course in intoxicated horses is short (<24-48 h), and animals may be found dead. Hepatic lesions caused by phosphine poisoning are not well described. Laboratory confirmation depends on detecting phosphine gas in gastric contents. Eight horses and a mule were exposed to zinc phosphide used to control prairie dogs on a Wyoming ranch. Three o...
Skeletal muscle from aged American Quarter Horses shows impairments in mitochondrial biogenesis and expression of autophagy markers.
Experimental gerontology    December 2, 2017   Volume 102 19-27 doi: 10.1016/j.exger.2017.11.022
Li C, White SH, Warren LK, Wohlgemuth SE.Aging is associated with decreased mitochondrial content and function in skeletal muscle, possibly due to compromised biogenesis and autophagic removal of dysfunctional mitochondria. The aim of this study was to compare markers of mitochondrial content and biogenesis and of autophagy between skeletal muscle from young and aged American Quarter Horses. Citrate synthase protein and mtDNA copy number were decreased in triceps brachii (TB) muscle (P<0.05) from aged horses, suggesting an age-related decline in mitochondrial content. Concomitantly, mRNA expression of PGC-1α and TFAM, regulators ...
Effects of transdermal lidocaine or lidocaine with prilocaine or tetracaine on mechanical superficial sensation and nociceptive thermal thresholds in horses.
Veterinary anaesthesia and analgesia    December 2, 2017   Volume 45, Issue 2 227-233 doi: 10.1016/j.vaa.2017.10.003
Söbbeler FJ, Kästner SB.To evaluate the transdermal local anaesthetic effect of lidocaine or lidocaine combined with prilocaine or tetracaine in horses. Methods: Experimental, randomized study. Methods: A total of five healthy adult warmblood horses. Methods: Horses were clipped bilaterally at the withers, cranial saddle area and caudal saddle area. Baseline measurements for mechanical superficial sensation via von Frey filaments and nociceptive thermal thresholds were performed. A 5% lidocaine patch (12 hour exposure, treatment L), a lidocaine/prilocaine cream (each 2.5%, treatment LP) and a lidocaine/tetracaine cre...
Retrospective evaluation of correlation and agreement between two recovery scoring systems in horses.
The Veterinary record    December 1, 2017   Volume 182, Issue 6 169 doi: 10.1136/vr.104546
Scarabelli S, Rioja E.No abstract available
Low Prevalence of Enzootic Equine Influenza Virus among Horses in Mongolia.
Pathogens (Basel, Switzerland)    November 30, 2017   Volume 6, Issue 4 61 doi: 10.3390/pathogens6040061
Sack A, Daramragchaa U, Chuluunbaatar M, Gonchigoo B, Bazartseren B, Tsogbadrakh N, Gray GC.Horses are critically important for Mongolian herders' livelihoods, providing transportation and food products, and playing important cultural roles. Equine influenza virus (EIV) epizootics have been frequent among Mongolia's horses, with five occurring since 1970. We sought to estimate the prevalence for EIV infection among horses and Bactrian camels with influenza-like illness between national epizootics. In 2016-2017, active surveillance for EIV was periodically performed in four aimags (provinces). Nasal swabs were collected from 680 horses and 131 camels. Seven of the horse swabs were "po...
Seroepidemiology of non-primate hepacivirus (NPHV) in Japanese native horses.
The Journal of veterinary medical science    November 29, 2017   Volume 80, Issue 1 186-189 doi: 10.1292/jvms.17-0527
Hayashi S, Tanaka T, Moriishi K, Hirayama K, Yamada A, Hotta K.Non-primate hepacivirus (NPHV) is recently identified as a closely related homologue of hepatitis C virus. The previous studies showed a high prevalence of NPHV infection among Japanese domestic horses originated from abroad. The historical distribution of NPHV among horses in Japan, therefore, is still unknown. In this study, seroepidemiological study of NPHV was conducted using 335 sera from five breeds of Japanese native horses. These horses are maintained as the pedigree and are reared apart from other horse breeds. The detection of antibodies against NPHV were conducted by western blot an...
In vivo evaluation of effects of sedation on results of acoustoelastography of the superficial digital flexor tendons in clinically normal horses.
American journal of veterinary research    November 29, 2017   Volume 78, Issue 12 1421-1425 doi: 10.2460/ajvr.78.12.1421
De Gasperi D, Dzierzak SL, Muir P, Vanderby R, Brounts SH.OBJECTIVE To assess the effects of sedation on results of acoustoelastography of the superficial digital flexor tendons (SDFTs) in clinically normal horses. ANIMALS 27 clinically normal horses. PROCEDURES For each horse, the pathology index (PI) for the SDFT of each thoracic limb was determined by use of acoustoelastography at 4 locations (5, 10, 15, and 20 cm distal to the accessory carpal bone). Horses were evaluated before and after they were sedated with a combination of detomidine hydrochloride (0.01 mg/kg, IV) and butorphanol tartrate (0.01 mg/kg, IV). A repeated-measures ANOVA was used ...
Workload of horses on a water treadmill: effect of speed and water height on oxygen consumption and cardiorespiratory parameters.
BMC veterinary research    November 28, 2017   Volume 13, Issue 1 360 doi: 10.1186/s12917-017-1290-2
Greco-Otto P, Bond S, Sides R, Kwong GPS, Bayly W, Léguillette R.Despite the use of water treadmills (WT) in conditioning horses, the intensity of WT exercise has not been well documented. The workload on a WT is a function of water height and treadmill speed. Therefore, the purpose of this study was to determine the effects of these factors on workload during WT exercise. Fifteen client-owned Quarter Horses were used in a randomized, controlled study. Three belt speeds and three water heights (mid cannon, carpus and stifle), along with the control condition (dry treadmill, all three speeds), were tested. Measured outcomes were oxygen consumption (V̇O2), v...
Emergence of H3N8 equine influenza virus in donkeys in China in 2017.
Veterinary microbiology    November 27, 2017   Volume 214 1-6 doi: 10.1016/j.vetmic.2017.11.033
Yang H, Xiao Y, Meng F, Sun F, Chen M, Cheng Z, Chen Y, Liu S, Chen H.Equine influenza virus is a major respiratory pathogen in horses. Although both horses and donkeys belong to the genus Equus, donkey infection with influenza viruses is rare. In March 2017, an influenza outbreak occurred in donkeys in Shandong province, China. The causative virus, A/donkey/Shandong/1/2017(H3N8), was isolated from a dead donkey. Genetic analysis indicated that the virus originated from influenza A (H3N8) clade 2 of the Florida sub-lineage that has been circulating in Asian equine populations. Comparison of the deduced amino acid sequence of the HA gene of this causative virus w...
MHC haplotype diversity in Persian Arabian horses determined using polymorphic microsatellites.
Immunogenetics    November 23, 2017   Volume 70, Issue 5 305-315 doi: 10.1007/s00251-017-1039-x
Sadeghi R, Moradi-Shahrbabak M, Miraei Ashtiani SR, Miller DC, Antczak DF.Previous research on the equine major histocompatibility complex (MHC) demonstrated strong correlations between haplotypes defined by polymorphic intra-MHC microsatellites and haplotypes defined using classical serology. Here, we estimated MHC diversity in a sample of 124 Arabian horses from an endangered strain native to Iran (Persian Asil Arabians), using a validated 10-marker microsatellite panel. In a group of 66 horses related as parent-offspring pairs or half-sibling groups, we defined 51 MHC haplotypes, 49 of which were new. In 47 of the remaining 58 unrelated horses, we could assign on...
The effects of Kinesio Taping on the trajectory of the forelimb and the muscle activity of the Musculus brachiocephalicus and the Musculus extensor carpi radialis in horses.
PloS one    November 22, 2017   Volume 12, Issue 11 e0186371 doi: 10.1371/journal.pone.0186371
Zellner A, Bockstahler B, Peham C.The present study aimed to investigate the effects of Kinesio Taping on the trajectory of the forelimb and the muscle activity of the M. brachiocephalicus and the M. extensor carpi radialis in horses. 19 horses and ponies of different breeds (body weight: 496±117 kg), gender (8 mares, 10 geldings and 3 stallions) and ages (14.9±6.9 years old) were analysed without Kinesio Tape ("no tape"), with Kinesio Tape (muscle facilitation application on both muscles of both sides, "with tape") and immediately after Kinesio Taping ("post tape") through kinematic motion analysis and surface electromyogra...
Does MnTBAP ameliorate DNA fragmentation and in vivo fertility of frozen-thawed Arabian stallion sperm?
Theriogenology    November 22, 2017   Volume 108 16-21 doi: 10.1016/j.theriogenology.2017.11.019
Shojaeian K, Nouri H, Kohram H.Overproduction of reactive oxygen species during sperm freeze-thawing process leads to membrane lipid peroxidation, DNA damage, motility loss, and subsequent death. This oxidative stress can be alleviated by the addition of some antioxidants to semen extenders prior to freezing. This study was performed to evaluate the in vitro effectiveness of MnTBAP (a cell permeable antioxidant) on stallion sperm freezability and in vivo fertility rate. Twenty-one ejaculates were, collected with missouri model artificial vagina (n = 3 stallions, seven ejaculate each), and diluted (1:2 v/v) with phosphoc...
Effects of selective α2 -adrenergic receptor agonists on electrical field-stimulated contractions of isolated bronchi in horses.
Journal of veterinary pharmacology and therapeutics    November 21, 2017   Volume 41, Issue 2 246-253 doi: 10.1111/jvp.12470
Menozzi A, Pozzoli C, Poli E, Colla C, Placenza G, Bertini S.We investigated the effects of different selective α -adrenergic receptor (AR) agonists (detomidine, medetomidine, xylazine, and brimonidine) on the contractions of horse-isolated bronchi induced by electrical field stimulation (EFS) and by carbachol. No effects were observed on the contraction induced by carbachol, while α -AR agonists reduced EFS-evoked contractions in a concentration-related fashion. The rank order of potency (pD ) was brimonidine (7.40 ± 0.20) >medetomidine (7.09 ± 0.24) >detomidine (6.13 ± 0.55) >xylazine (4.59 ± 0.16). The maximal effects (E ) were -56.3% ...
Reproductive effects of arteriviruses: equine arteritis virus and porcine reproductive and respiratory syndrome virus infections.
Current opinion in virology    November 21, 2017   Volume 27 57-70 doi: 10.1016/j.coviro.2017.11.005
Balasuriya UB, Carossino M.Equine arteritis virus (EAV) and porcine reproductive and respiratory syndrome virus (PRRSV) are the most economically important members of the family Arteriviridae. EAV and PRRSV cause reproductive and respiratory disease in equids and swine, respectively and constitute a significant economic burden to equine and swine industries around the world. Furthermore, they both cause abortion in pregnant animals and establish persistent infection in their natural hosts, which fosters viral shedding in semen leading to sexual transmission. The primary focus of this article is to provide an update on t...
Placental structure and function in different breeds in horses.
Theriogenology    November 20, 2017   Volume 108 136-145 doi: 10.1016/j.theriogenology.2017.11.007
Robles M, Peugnet PM, Valentino SA, Dubois C, Dahirel M, Aubrière MC, Reigner F, Serteyn D, Wimel L, Tarrade A, Chavatte-Palmer P.Ponies and sometimes draft horses are often used as experimental models for horses although size and metabolic parameters are known to vary between horse breeds. So far, there is little information about differences of placental structure and no information about differences of placental function between breeds. The aim of this study was to investigate differences in placental size, structure and function at birth in relation to foal size and weight in ponies, Saddlebred and draft horses. Pony, Saddlebred and draft horse pregnancies were obtained by artificial insemination over 2 successive br...
West Nile Virus Lineage 2 in Horses and Other Animals with Neurologic Disease, South Africa, 2008-2015.
Emerging infectious diseases    November 18, 2017   Volume 23, Issue 12 2060-2064 doi: 10.3201/eid2312.162078
Venter M, Pretorius M, Fuller JA, Botha E, Rakgotho M, Stivaktas V, Weyer C, Romito M, Williams J.During 2008-2015 in South Africa, we conducted West Nile virus surveillance in 1,407 animals with neurologic disease and identified mostly lineage 2 cases in horses (7.4%, 79/1,069), livestock (1.5%, 2/132), and wildlife (0.5%, 1/206); 35% were fatal. Geographic correlation of horse cases with seropositive veterinarians suggests disease in horses can predict risk in humans.
Pennington et al.: First demonstration of equid gammaherpesviruses within the gastric mucosal epithelium of horses. Virus Research volume 242, 15 October 2017, pages 30-36.
Virus research    November 17, 2017   Volume 244 116 doi: 10.1016/j.virusres.2017.11.016
Löhr M.No abstract available
Phenylbutazone induces equine glandular gastric disease without decreasing prostaglandin E2 concentrations.
Journal of veterinary pharmacology and therapeutics    November 16, 2017   Volume 41, Issue 2 239-245 doi: 10.1111/jvp.12464
Pedersen SK, Cribb AE, Read EK, French D, Banse HE.In equids, phenylbutazone at high doses induces gastric disease, primarily in the glandular portion of the stomach. However, the mechanism of nonsteroidal anti-inflammatory drug (NSAID)-induced gastric disease in horses has yet to be determined. While phenylbutazone-associated ulceration is often attributed to a decrease in basal gastric prostaglandins, this has not been demonstrated in the horse. Twelve horses were randomly assigned to treatment (n = 6; 4.4 mg/kg phenylbutazone PO in 20 ml molasses q 12 hr for 7 days) or placebo (n = 6; 20 ml molasses PO q 12 hr for 7 days) groups....
Equine Intestinal Mucosal Pathobiology.
Annual review of animal biosciences    November 16, 2017   Volume 6 157-175 doi: 10.1146/annurev-animal-030117-014748
Blikslager A, Gonzalez L.The equine intestinal mucosa is intimately involved in maintaining homeostasis both on a systemic level by controlling extracellular fluid movement and at the local level to maintain barrier function. Horses are particularly susceptible to the clinical syndrome of colic, with the most severe cases involving strangulating obstruction that induces ischemia. Because of the mucosal vascular architecture, the mucosal epithelium is particularly susceptible to ischemic injury. The potential for reperfusion injury has been investigated and found to play a minimal role. However, inflammation does affec...
Serological evidence for the co-circulation of two lineages of influenza D viruses in equine populations of the Midwest United States.
Zoonoses and public health    November 14, 2017   Volume 65, Issue 1 e148-e154 doi: 10.1111/zph.12423
Nedland H, Wollman J, Sreenivasan C, Quast M, Singrey A, Fawcett L, Christopher-Hennings J, Nelson E, Kaushik RS, Wang D, Li F.Influenza D virus (IDV) is a newly described influenza type of the Orthomyxoviridae virus family that was first isolated from diseased swine in 2011 and has subsequently been detected in cattle around the world in 2014. In addition, serological evidence for IDV infection in humans has been recently established. Despite all the progress, the full range of susceptible hosts for this novel virus has yet to be determined, but includes swine, bovine, small ruminants and human. This study was designed to determine if equine is a possible host to this newly emerging influenza virus. Three hundred and...
The biomechanical construction of the horse’s body and activity patterns of three important muscles of the trunk in the walk, trot and canter.
Journal of animal physiology and animal nutrition    November 14, 2017   Volume 102, Issue 2 e818-e827 doi: 10.1111/jpn.12840
Kienapfel K, Preuschoft H, Wulf A, Wagner H.The activity patterns of trunk muscles are commonly neglected, in spite of their importance for maintaining body shape. Analysis of the biomechanics of the trunk under static conditions has led to predictions of the activity patterns. These hypotheses are tested experimentally by surface electromyography (EMG). Five horses, with and without a rider, were examined in the walk, trot and canter. Footfall was synchronised with EMG by an accelerometer. Averages of ten consecutive cycles were calculated and compared by statistical methods. The start and stop times of the muscle activities of 5-10 un...
The Relationship between Intuitive Action Choices and Moral Reasoning on Animal Ethics Issues in Students of Veterinary Medicine and Other Relevant Professions.
Journal of veterinary medical education    November 13, 2017   1-24 doi: 10.3138/jvme.0117-016
Verrinder JM, Phillips CJC.With growing understanding of animals' capabilities, and public and organizational pressures to improve animal welfare, moral action by veterinarians and other relevant professionals to address animal issues is increasingly important. Little is known about how their action choices relate to their moral reasoning on animal ethics issues. A moral judgment measure, the VetDIT, with three animal and three non-animal scenarios, was used to investigate the action choices of 619 students in five animal- and two non-animal-related professional programs in one Australian university, and how these relat...
Neosaxitoxin, a Paralytic Shellfish Poison toxin, effectively manages bucked shins pain, as a local long-acting pain blocker in an equine model.
Toxicon : official journal of the International Society on Toxinology    November 13, 2017   Volume 141 15-17 doi: 10.1016/j.toxicon.2017.11.004
Riquelme G, Sepúlveda JM, Al Ghumgham Z, Del Campo M, Montero C, Lagos N.Local anesthesia is an effective method to control pain. Neosaxitoxin is a phycotoxin whose molecular mechanism includes a reversible inhibition of voltage-gated sodium channels at the axonal level, impeding nerve impulse propagation. The present study was designed to evaluate the clinical efficacy of Neosaxitoxin as a local long-acting pain blocker in horse bucked shins, and it was found to effectively control pain. While Neosaxitoxin and Gonyautoxin, another Paralytic Shellfish Poison (PSP) toxin, have been successfully used in humans as long-lasting pain blockers, this finding marks the fir...
[Vigilance for veterinary medicinal products: Reports of adverse reactions in the year 2016].
Schweizer Archiv fur Tierheilkunde    November 13, 2017   Volume 159, Issue 11 581-585 doi: 10.17236/sat00132
Müntener CR, Müntener C, Kupper J, Naegeli H, Gassner B.A total of 253 reports of adverse reactions to veterinary medicinal products were received during the year 2016 representing a decrease of 13% compared to the previous year (292 reports). The majority of the reports described reactions affecting companion animals (178 dogs and 32 cats) as well as cattle (17 reports) and horses (10 reports). Most of the reactions reported were linked to the use of antiparasitics (145 reports), hormone products (26 reports) and antiinfectives (10 reports). 32 reports were generated from consultations with Tox Info Suisse in Zürich and involved mainly the excess...
Spatio-temporal analysis and visualisation of the anthrax epidemic situation in livestock in Kazakhstan over the period 1933-2016.
Geospatial health    November 13, 2017   Volume 12, Issue 2 589 doi: 10.4081/gh.2017.589
Abdrakhmanov SK, Mukhanbetkaliyev YY, Korennoy FI, Karatayev BS, Mukhanbetkaliyeva AA, Abdrakhmanova AS.An analysis of the anthrax epidemic situation among livestock animals in the Republic of Kazakhstan over the period 1933-2016 is presented. During this time, 4,064 anthrax outbreaks (mainly in cattle, small ruminants, pigs and horses) were recorded. They fall into five historical periods of increase and decrease in the annual anthrax incidence (1933-1953; 1954-1968; 1969-1983; 1984- 2001; and 2002-2016), which has been associated with changes in economic activity and veterinary surveillance. To evaluate the temporal trends of incidence variation for each of these time periods, the following me...
First molecular characterisation of a Brazilian Burkholderia mallei strain isolated from a mule in 2016.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases    November 13, 2017   Volume 57 117-120 doi: 10.1016/j.meegid.2017.11.014
Laroucau K, Lucia de Assis Santana V, Girault G, Martin B, Miranda da Silveira PP, Brasil Machado M, Joseph M, Wernery R, Wernery U, Zientara S....We present the first molecular characterisation based on MLVA and SNP analysis of a strain of Burkholderia mallei isolated from a mule found dead in Brazil in 2016.
Pharmacokinetics of inorganic cobalt and a vitamin B12 supplement in the Thoroughbred horse: Differentiating cobalt abuse from supplementation.
Equine veterinary journal    November 12, 2017   Volume 50, Issue 3 343-349 doi: 10.1111/evj.12774
Hillyer LL, Ridd Z, Fenwick S, Hincks P, Paine SW.While cobalt is an essential micronutrient for vitamin B synthesis in the horse, at supraphysiological concentrations, it has been shown to enhance performance in human subjects and rats, and there is evidence that its administration in high doses to horses poses a welfare threat. Animal sport regulators currently control cobalt abuse via international race day thresholds, but this work was initiated to explore means of potentially adding to application of those thresholds since cobalt may be present in physiological concentrations. Objective: To devise a scientific basis for differentiation b...
Surveillance and diagnosis of zoonotic foodborne parasites.
Food science & nutrition    November 12, 2017   Volume 6, Issue 1 3-17 doi: 10.1002/fsn3.530
Zolfaghari Emameh R, Purmonen S, Sukura A, Parkkila S.Foodborne parasites are a source of human parasitic infection. Zoonotic infections of humans arise from a variety of domestic and wild animals, including sheep, goats, cattle, camels, horses, pigs, boars, bears, felines, canids, amphibians, reptiles, poultry, and aquatic animals such as fishes and shrimp. Therefore, the implementation of efficient, accessible, and controllable inspection policies for livestock, fisheries, slaughterhouses, and meat processing and packaging companies is highly recommended. In addition, more attention should be paid to the education of auditors from the quality c...
West Nile virus in horses during the summer and autumn seasons of 2015 and 2016, Portugal.
Veterinary microbiology    November 11, 2017   Volume 212 75-79 doi: 10.1016/j.vetmic.2017.11.008
Barros SC, Ramos F, Fagulha T, Duarte M, Henriques AM, Waap H, Luís T, Costa T, Amador R, Quintans S, Fevereiro M.West Nile fever (WNF) is an emergent disease in Europe, under surveillance in the European Union. Following a 5-year period of apparent silence (autumn 2010 to summer 2015), West Nile virus (WNV) reemerged in the South of Portugal, in July 2015. Here we present data from the onset, geographic location within mainland Portugal, and outcome of clinical cases of WNV infection in horses in 2015 and 2016. During the transmission seasons of 2015 and 2016, twenty-seven horses, most symptomatic (n=20) were found positive to IgM, pr-E immunoglobulins and VNT, leading to the subsequent report to Animal ...