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Topic:Case Reports
Case reports in equine medicine provide detailed accounts of individual horses' clinical presentations, diagnostic processes, treatments, and outcomes. These reports are valuable for documenting rare conditions, novel treatment approaches, or unique clinical insights that may not be captured in larger studies. By focusing on individual cases, these reports contribute to the broader understanding of equine health and disease management. They often include comprehensive information on the horse's history, clinical findings, diagnostic tests, therapeutic interventions, and follow-up evaluations. This page assembles peer-reviewed case reports and scholarly articles that explore diverse aspects of equine health, offering insights into specific medical scenarios and their implications for veterinary practice.
Bacterial meningitis after sinus surgery in five adult horses. To report meningoencephalitis as a complication after paranasal sinus surgery in 5 horses. Methods: Case series. Methods: Adult horses (n = 5). Methods: Medical records (2005-2010) of 5 horses that developed neurologic signs after sinus surgery were reviewed to identify potential risk factors, cause(s), or common pathways for infection. Results: Underlying diseases were primary (n = 1) and secondary sinusitis (4) because of apical dental infection (1), sinus cyst (2), or masses in the ethmoturbinate region (2). Horses were treated by conventional surgical approaches and aftercare inclu...
Plate fixation for management of plantar instability of the distal tarsus/proximal metatarsus in 5 horses. To report plate fixation for management of traumatic injuries resulting in plantar instability of the proximal intertarsal (PIT) and tarsometatarsal (TMT) joints. Methods: Case series. Methods: Medical records (October 1988 to August 2007) of horses that had internal fixation of the distal aspect of the tarsus were reviewed. Horses that had a broad dynamic compression plate (DCP) or broad locking compression plate (LCP) applied on the plantar-lateral aspect of the tarsus extending from the proximal calcaneus to the proximal one third of the metatarsus were included. Signalment, clinical signs,...
A chromosomal region on ECA13 is associated with maxillary prognathism in horses. Hereditary variations in head morphology and head malformations are known in many species. The most common variation encountered in horses is maxillary prognathism. Prognathism and brachygnathism are syndromes of the upper and lower jaw, respectively. The resulting malocclusion can negatively affect teeth wear, and is considered a non-desirable trait in breeding programs. We performed a case-control analysis for maxillary prognathism in horses using 96 cases and 763 controls. All horses had been previously genotyped with a commercially available 50 k SNP array. We analyzed the data with a mixe...
Long term outcome after laser assisted modified Forssell’s in cribbing horses. To (1) report long-term outcome after laser assisted modified Forssell's procedure; (2) describe the prevalence of postoperative complications; and (3) identify risk factors associated with outcome. Methods: Retrospective case series. Methods: Horses (n = 119). Methods: Medical records (1994-2012) of horses that had laser assisted modified Forssell's procedure were reviewed. Signalment, preoperative duration of cribbing, postoperative complications and outcome were recorded. Results: Follow-up was available for 90 horses; 76 had stopped cribbing for >1 year. Of 14 horses that resumed cr...
Acinar cell carcinoma of exocrine pancreas in two horses. Two horses were presented with non-specific clinical signs of several weeks' duration and were humanely destroyed due to a poor prognosis. At necropsy examination, both horses had multiple small, white nodules replacing pancreatic tissue and involving the serosal surface of the abdominal cavity, the liver and the lung. Microscopically, neoplastic cells were organized in acini and contained abundant (case 1) or sparse (horse 2) intracytoplasmic zymogen granules. Immunohistochemically, both tumours expressed amylase and pan-cytokeratin, but not insulin or neuron-specific enolase. In case 2, a lo...
Clinical outcome after intra-articular administration of bone marrow derived mesenchymal stem cells in 33 horses with stifle injury. To report outcome of horses with femorotibial lesions (meniscal, cartilage or ligamentous) treated with surgery and intra-articular administration of autologous bone marrow derived mesenchymal stem cells (BMSCs). Methods: Prospective case series. Methods: Horses (n = 33). Methods: Inclusion criteria included horses that had lameness localized to the stifle by diagnostic anesthesia, exploratory stifle arthroscopy and subsequent intra-articular administration of autologous BMSCs. Case details and follow-up were gathered from medical records, owner, trainer or veterinarian. Outcome was defined as...
A new technique for subtotal (cranial wedge) ostectomy in the treatment of impinging/overriding spinous processes: description of technique and outcome of 25 cases. Surgical management for overriding spinous processes of the thoracolumbar vertebrae (SPs) is often favoured when conservative therapies have failed, pathology is severe, or in competition horses constrained by drug withdrawal periods. Objective: To evaluate whether subtotal (cranial wedge) ostectomy represents an effective treatment for overriding SPs, with short surgery time and low complication rates, maintains the contour of the spine and produces a functionally and cosmetically better outcome than previously reported surgical techniques for management of overriding/impinging SPs. Methods: ...
Successful microsurgical revascularization of an almost totally amputated ear lobe by horse bite. Total or subtotal amputation of the external ear related to horse bite is an uncommon situation. In our case, we report successful microsurgical revascularization of almost totally amputated ear of a 75-year-old male patient caused by a horse bite.
Oxyuris equi: lack of efficacy in treatment with macrocyclic lactones. Whilst anthelminthic resistance of small strongyles is well documented, anthelmintic failures against infections with Oxyuris equi have scarcely been published so far. We describe two cases of equine oxyurosis and the anthelminthic failure of macrocyclic lactones (moxidectin, ivermectin) resulting in persistent O. equi infections with continuous egg shedding. The horses were kept in two different herds in the federal state of Hessia, Germany. Herd A kept two geldings: an 8-year-old Welsh-Cob-Mix and a 7-year-old Haflinger. Herd B was composed of four animals: 2 Connemara-mares, 31 and 19 years...
Long-term survival in horses with strangulating obstruction of the small intestine managed without resection. Although many studies have described results after small intestinal resection and anastomosis in horses, few have described the outcome in horses with strangulating lesions managed without resection. Objective: To examine short- and long-term recoveries in horses with strangulated small intestine that was judged to be viable during surgery and not resected. Methods: Retrospective analysis of case records. Methods: Data were reviewed from all cases (35 horses) with colic caused by small intestinal strangulation that underwent surgery between 1996 and 2011 at 2 university hospitals and that were...
Dynamic compression plate (DCP) fixation of propagating medial condylar fractures of the third metacarpal/metatarsal bone in 30 racehorses: retrospective analysis (1990-2005). An in-depth review of dynamic compression plate (DCP) fixation of propagating medial condyle fractures of the third metacarpus or metatarsus has not been previously reported. Objective: To describe the technique, evaluate short-term outcome and long-term race performance of racehorses that underwent DCP fixation for repair of propagating or spiralling medial condylar fractures of the third metacarpal (McIII) or metatarsal (MtIII) bone. Methods: Retrospective case series. Methods: The surgical case records of 30 horses with propagating fractures of the medial condyle of McIII or MtIII were revi...
Extensive rostral mandibulectomy for treatment of ameloblastoma in a horse. To report long-term outcome in a mare that had extensive rostral mandibulectomy to remove an ameloblastoma. Methods: Clinical report. Methods: A 21-year-old mare. Methods: An ameloblastoma, located in the rostral aspect of the mandible, was removed by complete en-bloc resection of the tumor, removing most of the mandibular symphysis. Results: The day after surgery, the remaining mandibular symphysis (<5 mm) fractured causing marked instability of the hemi-mandibles. Partial wound dehiscence occurred 5 days after surgery; however, the mare was able to eat well and the incision healed within 2...
Treatment of six cases of equine corneal stromal abscessation with intracorneal injection of 5% voriconazole solution. To describe a reproducible technique for intrastromal injection in the standing horse for treatment of corneal stromal abscessation. Methods: A retrospective clinical study addressing the history, treatment, and outcome of six equids (six eyes) that received intrastromal voriconazole injection. Methods: Equids having a deep stromal abscess suspected to be of fungal origin were administered intrastromal injection of 5% voriconazole solution under standing sedation in an effort to bring about enhanced resolution of clinical disease. Results: Intracorneal administration of 5% voriconazole solutio...
Exploration of known stereotypic behaviour-related candidate genes in equine crib-biting. Crib-biting in horses is a stereotypic oral behaviour. Genetic susceptibility has been suggested on a causal basis, together with environmental factors such as stress, gastric discomfort and frustration caused by stall restrictions. This study aimed to test the associations of known or suspected stereotypic genes with equine crib-biting, including Ghrelin, Ghrelin receptor, Leptin, Dopamine receptor, μ-opioid receptor, N-cadherin, Serotonin receptor and Semaphorin. We conducted a candidate gene study with a case-control design, including 98 crib-biting and 135 control horses of two breeds, Fi...
Imaging diagnosis–muscular hypertrophy of the small intestine and pseudodiverticula in a horse. A 14-year-old Thoroughbred gelding was presented for chronic colic and weight loss. Transcutaneous and transrectal abdominal ultrasonography revealed distended, thickened small intestine with primary thickening of the muscularis and a focally more thickened loop with an echoic structure crossing the wall from the mucosa to the serosa. Visualization of diffuse thickening of the muscularis (muscular hypertrophy of the small intestine) and a focal lesion (pseudodiverticulum) helped clinicians make informed decisions. This case illustrates the importance of transabdominal and transrectal ultrasono...
Radiographic appearance of maxillary sinus feed impaction in a horse. A 15-year-old Belgian gelding presented in respiratory distress, with bilateral mucopurulent nasal discharge, and right-sided epistaxis. The horse had a 5-year history of dental disease and had been recently losing weight. Radiographs indicated tooth root abscessation of the right maxillary third molar tooth and probable maxillary sinus feed impaction. These findings were confirmed at surgery and necropsy. The stippled, granular radiographic appearance described here is highly characteristic of sinus feed impaction.
Case-Study Investigation of Equine Maternity via PCR-RFLP: A Biochemistry Laboratory Experiment. A simple and robust biochemistry laboratory experiment is described that uses restriction fragment length polymorphism (RFLP) of polymerase chain reaction (PCR) products to verify the identity of a potentially valuable horse. During the first laboratory period, students purify DNA from equine samples and amplify two loci of mitochondrial DNA. During the second laboratory period, students digest PCR products with restriction enzymes and analyze the fragment sizes through agarose gel electrophoresis. An optional step of validating DNA extracts through realtime PCR can expand the experiment to th...
Frontal plane fractures of the accessory carpal bone and implications for the carpal sheath of the digital flexor tendons. Accurate radiological and ultrasonographic descriptions of frontal plane fractures of the accessory carpal bone (ACB) are lacking, and implications of these fractures for the carpal sheath and its contents have not previously been reported. Objective: Aims were as follows: 1) to describe the location and radiological features of frontal plane fractures of the ACB; 2) to document communication of displaced fractures with the carpal sheath and consequent injury to the deep digital flexor tendon (DDFT); 3) to describe ultrasonographic identification of lesions; and 4) to report tenoscopic evaluat...
Primary intraparotid peripheral nerve sheath tumour with characteristics of benign schwannoma in a horse. Schwannomas arising in the parotid gland are rare in man and are not documented in domestic animals. This report describes the clinical, morphological and immunohistochemical findings of a benign schwannoma in the parotid gland of a 12-year-old warmblood gelding. A slow-growing mass was surgically excised from the parotid gland and did not recur within the following 6 months. The tumour was well circumscribed and was composed of densely packed spindle cells partly arranged in an Antoni A pattern and intermixed with hypocellular areas resembling the Antoni B pattern. Tumour cells expressed vime...
Cutaneous leishmaniosis in a horse from northern Portugal. The first case of cutaneous leishmaniosis in a horse from the north of Portugal, with a 1.5 cm in diameter ulcerated nodular lesion on the left face, is reported. The skin nodule was surgically excised and assessed by histopathology, including an immunohistochemistry method applied for the first time to equine tissues which clearly demonstrated leishmanial amastigote forms. Two serological determinations with the direct agglutination test performed 13 months apart showed seroconversion specific for Leishmania from a <25 to a 200 antibody titre. Polymerase chain reaction followed by kinetopl...
Postoperative Clostridium difficile infection with PCR ribotype 078 strain identified at necropsy in five Thoroughbred racehorses. Clostridium difficile is an important cause of acute enterocolitis in horses. We describe five cases of C difficile infection occurring postoperatively in Thoroughbred racehorses. Following diarrhoea or colic accompanied by a marked increase in packed cell volume (to ≥60 per cent) and leucopenia (≤4000 cells/μl) within two to four days after surgery in all five horses, four of them died or were euthanased because of colitis or severe diarrhoea. In these four horses, necrotising entero-typhlo-colitis was revealed by postmortem examination, and C difficile was recovered from the contents of...
Weissella confusa septicemia in a foal. Weissella confusa is a Gram-positive bacterium that has been identified in environmental and food samples from around the world. Rare cases of bacteremia in immunocompromised people have been reported. A 2-day-old foal was presented for weakness and suspected sepsis. Blood culture yielded pure growth of a Gram-positive coccobacillus, which was identified as W. confusa through sequencing of the 16S ribosomal DNA. Although the foal initially responded to antimicrobial therapy with ceftiofur and metronidazole, it later developed septic complications of the right tarsocrural joint and right digita...
Diagnoses, clinical pathology findings, and treatment outcome of geriatric horses: 345 cases (2006-2010). To compare clinical, clinical pathology, and outcome variables between geriatric and nongeriatric horses. Methods: Retrospective case-control study. Methods: 690 horses (345 horses ≥ 20 years old and 345 horses > 1 and 1 and < 20 years old. Results: Mean ± SD age was 23.9 ± 4.6 years for cases and 9.2 ± 3.6 years for controls. Arabian and pony breeds were significantly overrepresented in the geriatric group, compared with the control group. Diagnoses related to the digestive system, musculoskeletal system, and respiratory system were most common in this hospital population overall ...
Clinical, radiographic, ultrasonographic and computed tomographic features of nonseptic osteitis of the axial border of the proximal sesamoid bones. Lysis of the axial aspect of equine proximal sesamoid bones (PSBs) is a rare condition reported to have septic or traumatic origins. Limited information exists regarding imaging of nonseptic axial osteitis of a PSB. Objective: To report the clinical, radiographic, ultrasonographic, computed tomographic and intra-arterial contrast-enhanced computed tomographic abnormalities in horses with axial nonseptic osteitis of a PSB. Methods: Retrospective clinical study. Methods: Eighteen horses diagnosed with nonseptic osteitis of the axial border of a PSB between 2007 and 2012 were reviewed retrospecti...
Identification and treatment of osteochondritis dissecans of the distal sagittal ridge of the third metacarpal bone. Osteochondritis dissecans (OCD) of the distal sagittal ridge of the third metacarpal bone (McIII) has not previously been described in the literature. Objective: To describe the clinical, radiological and arthroscopic features of OCD of the distal sagittal ridge of the McIII and to report outcome in a series of cases. Methods: Retrospective case series. Methods: Case records and images of horses with OCD of the distal sagittal ridge of the McIII admitted to a single referral centre between February 2006 and February 2013 were reviewed. Follow-up information was obtained by telephone questionna...
Use of lomustine (CCNU) in a case of cutaneous equine lymphoma. A 12-year-old gelding was diagnosed with recurrent lymphoma in multiple cutaneous sites. A highly invasive preputial mass caused urethral obstruction. The horse was treated with surgery and chemotherapy consisting of lomustine (CCNU) and prednisolone. The treatment was well-tolerated and effective. This is the first reported use of lomustine (CCNU) in a horse for the treatment of equine lymphoma. Utilisation de lomustine (CCNU) dans un cas de lymphone cutané équin. Un hongre âgé de 12 ans a été diagnostiqué avec un lymphome récurrent sur plusieurs sites cutanés. Une masse préputiale ...
Systemic and respiratory oxidative stress in the pathogenesis and diagnosis of Rhodococcus equi pneumonia. Oxidative stress (OS) is most simply defined as an imbalance between oxidants and antioxidants. Oxidative stress has been suggested to play roles in various equine respiratory diseases and the significance of OS in the pathogenesis of Rhodococcus equi pneumonia is unknown. Objective: To measure and relate biomarkers of OS to lesions consistent with R. equi pneumonia. Methods: Case-control study. Methods: Various OS biomarkers were measured from blood and exhaled breath condensate (EBC) samples collected from 26 foals between 1 and 2 months of age (n = 12 cases and n = 14 controls) on 2 Thoro...
