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Topic:Dermatology

Dermatology in horses encompasses the study and treatment of skin-related conditions affecting equine species. Equine dermatological issues can arise from various causes, including infections, allergies, parasites, and environmental factors. Common skin conditions in horses include dermatitis, ringworm, and sarcoids. These conditions can affect the health and performance of horses, necessitating accurate diagnosis and effective management. Diagnostic approaches often involve clinical examination, skin scrapings, biopsies, and laboratory tests. This page compiles peer-reviewed research studies and scholarly articles that explore the etiology, diagnosis, treatment, and management of dermatological disorders in horses.
Safety of a feed additive consisting of a tincture derived from the roots of Gentiana lutea L. (gentian tincture) for all animal species (FEFANA asbl).
EFSA journal. European Food Safety Authority    February 24, 2023   Volume 21, Issue 2 e07869 doi: 10.2903/j.efsa.2023.7869
Bampidis V, Azimonti G, Bastos ML, Christensen H, Durjava M, Kouba M, López-Alonso M, Puente SL, Marcon F, Mayo B, Pechová A, Petkova M, Ramos F....Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety of a tincture derived from L. (gentian tincture). It is intended to be used as a sensory additive for all animal species. The product is a water/ethanol solution, with a dry matter content of approximately 4.3% and it contains on average 0.0836% polyphenols (of which 0.0463% are flavonoids and 0.0027% xanthones) and 0.0022% gentiopicroside. The additive is intended for use in complete feed or drinking water up to a maximum level of 50 mg tincture/kg for all animal species, except ho...
The application of videodermoscopic examination in assessing the skin and its products in pure Arabian horses in the summer and winter seasons.
Polish journal of veterinary sciences    September 27, 2022   Volume 25, Issue 3 403-409 doi: 10.24425/pjvs.2022.142024
Pomorska-Zniszczyńska A, Szczepanik MP, Kalisz G, Adamczyk N, Tarach M, Sobuś M, Abramowicz B.Videodermoscopic examinations have only recently started to be used in veterinary medicine and usually involve a small group of animals. The aim of this study was to compare specific dermoscopic parameters in selected areas of the body of Arabian horses in the summer and winter seasons. The research was conducted between 2018-2019. The procedure was performed on the left side of the horse's body in seven areas: head, neck, chest, flank, rump, mane, and tail. 42 purebred Arabian horses aged 1-25 (median), 39 mares and 3 stallions were qualified for the study. An Italian Video-Dermascope 7 (Medi...
Safety of a feed additive consisting of a tincture derived from Verbascum thapsus L. (great mullein tincture) for use in all animal species (MANGHEBATI SAS).
EFSA journal. European Food Safety Authority    July 28, 2021   Volume 19, Issue 7 e06711 doi: 10.2903/j.efsa.2021.6711
Bampidis V, Azimonti G, Bastos ML, Christensen H, Fašmon Durjava M, Kouba M, López-Alonso M, López Puente S, Marcon F, Mayo B, Pechová A....The tincture derived from L. (great mullein tincture) is intended to be used as a sensory additive in feed for all animal species. The product is a water/ethanol solution, with a dry matter content of ˜ 2.8% and contains on average 0.216% polyphenols including 0.093% flavonoids. According to a previous assessment, the additive was not characterised in full and about 82% of the dry matter fraction remained uncharacterised (representing 2.26% of the tincture). There was also uncertainty on the potential presence of iridoid glycosides in the tincture. Therefore, the Panel on Additives and Prod...
Antifungal susceptibility of dermatophytes from racehorses in Japan.
Veterinary dermatology    June 29, 2021   Volume 32, Issue 5 474-e129 doi: 10.1111/vde.12993
Watanabe R, Huruta H, Ueno Y, Nukada T, Niwa H, Shinyashiki N, Kano R.Luliconazole (LCZ) is an imidazole antifungal medication that exhibits excellent activity against dermatophytes. As a topical cream and lotion (approved for human use), LCZ has demonstrated a broad spectrum of activity against human dermatophytoses. Objective: This is the first study to investigate the in vitro susceptibility of clinical isolates from horse dermatophytoses to LCZ. Methods: No animals were used in this study. Methods: In the present study, the in vitro susceptibilities of clinical isolates of dermatophytes to LCZ, clotrimazole (CTZ), miconazole (MCZ) and terbinafine (TRF) wer...
The use of domestic animals and their derivative products in contemporary Spanish ethnoveterinary medicine.
Journal of ethnopharmacology    February 5, 2021   Volume 271 113900 doi: 10.1016/j.jep.2021.113900
González JA, Vallejo JR.This review documents the wide and varied repertoire of traditional practices and remedies based on the use of domestic animals in Spanish ethnoveterinary medicine (EVM) from the early 20th century to the present. Empirical practices, both ritual and magical, are recorded, and these EVM data are compared with those of other countries in the Mediterranean region and Latin America. The data collected here could form a scientific foundation for future inventories of local veterinary knowledge (LVK) and research addressing the discovery of new drugs for livestock and the validation of the effects....
Fatal lancehead pit viper (Bothrops spp.) envenomation in horses.
Toxicon : official journal of the International Society on Toxinology    September 6, 2019   Volume 170 41-50 doi: 10.1016/j.toxicon.2019.09.002
Machado M, Wilson TM, Ribeiro de Sousa DE, Lopes Câmara AC, Furlan FH, Silva Almeida E Macêdo JT, Pupin RC, Amaral de Lemos RA, Armién AG....Snake bite envenomations in farm animals are generally overestimated as the cause of mortality in rural areas in Latin America. However, most cases are based only on anecdotal information and assumptions, and lack diagnostic evidence. There are few proven reports of envenomation and death in horses caused by snakebites from members of the Bothrops genus (lancehead pit vipers). This study presents epidemiological and clinical-pathological findings of fatal bothropic envenomation in horses from Central Western Brazil in order to contribute to the correct diagnosis of this condition. A survey of ...
Ethnoveterinary knowledge of farmers in bilingual regions of Switzerland – is there potential to extend veterinary options to reduce antimicrobial use?
Journal of ethnopharmacology    August 26, 2019   Volume 246 112184 doi: 10.1016/j.jep.2019.112184
Mertenat D, Cero MD, Vogl CR, Ivemeyer S, Meier B, Maeschli A, Hamburger M, Walkenhorst M.In the pre-antibiotic era, a broad spectrum of medicinal plants was used to treat livestock. This knowledge was neglected in European veterinary medicine for decades but kept alive by farmers. Emergence of multidrug resistant bacterial strains requires a severely restricted use of antibiotics in veterinary medicine. We conducted a survey on the ethnoveterinary knowledge of farmers in the bilingual (French and German speaking) Western region of Switzerland, namely the cantons of Fribourg, Neuchâtel and Jura, and in the French speaking part of the canton of Bern. Objective: To find out whether ...
Skin disease in donkeys (Equus asinus): a retrospective study from four veterinary schools.
Veterinary dermatology    March 4, 2019   Volume 30, Issue 3 247-e76 doi: 10.1111/vde.12733
White SD, Bourdeau PJ, Brément T, Vandenabeele SI, Haspeslagh M, Bruet V, Sloet van Oldruitenborgh-Oosterbaan MM.Donkeys are important throughout the world as work animals and occasionally as pets or a meat source. Most descriptions of skin disease in donkeys are reported in small case series, textbooks or review articles. Objective: To document skin diseases and their prevalence in donkeys and to investigate predilections for the most common conditions. Methods: Case populations at four veterinary schools totalling 156 donkeys. Methods: A retrospective study was performed by searching computerized medical records, using the key word "donkey", at the School of Veterinary Medicine, University of Californi...
Comparative effectiveness of Sumaq and Neem extract cream, Eniloconazole and glycerine iodine on dermatophytosis in Arabian horses: a randomized clinical trial.
Tropical animal health and production    December 15, 2018   Volume 51, Issue 4 905-910 doi: 10.1007/s11250-018-1773-6
Sayed-Ahmed MZ, Ahdy AM, Younis EE, El-Khodery SA, Baraka HN.Dermatophytosis is a contagious fungal disease among animal communities. The major concerns of dermatophytosis are cost of treatment, difficulty of control, and the public health consequences. The objective of the present study was to compare the clinical efficacy of Sumaq and Neem extract cream with that of traditional treatments, eniloconazole and glycerine iodine, on dermatophytosis in Arabian horses. For this purpose, 37 Arabian horses with dermatophytosis had been used. Fungal isolation and identification for each horse were carried out by standard microbiological procedures. Sumaq (Rhus ...
Comparing dermoscopy and histological examination of normal equine skin.
Veterinary dermatology    November 15, 2017   Volume 29, Issue 2 170-e63 doi: 10.1111/vde.12511
Tomich LM, Pieper JB, Stern AW.Dermoscopy is a noninvasive diagnostic technique that allows visualization of structures of the superficial dermis not visible with the naked eye. Objective: To assess the usefulness and applicability of dermoscopy for evaluation of healthy equine skin. Methods: Twelve healthy horses from a research herd. Methods: Five regions (cheek, lateral neck, dorsum, flank and abdomen) were examined with contact dermoscopy using both nonpolarized and polarized light at both 17-fold and 24-fold magnification. These findings were compared to histological features of skin biopsies cut both longitudinally an...
Dermoscopic analysis of the skin of healthy warmblood horses: a descriptive study of 34 cases in Italy.
Veterinary dermatology    November 1, 2017   Volume 29, Issue 2 165-e61 doi: 10.1111/vde.12508
Legnani S, Zini E, Roccabianca P, Funiciello B, Zanna G.Dermoscopy is a diagnostic tool that has been introduced into small animal dermatology for the evaluation of hair and the skin surface. To the best of the authors' knowledge, the use of this technique on horses and the dermoscopic appearance of equine hair and skin have yet to be reported. Objective: To assess the feasibility of dermoscopy, and to describe hair and skin surface features of healthy warmblood horses. Methods: Thirty four client-owned, healthy adult horses. Methods: Six body regions (head, neck, dorsal thorax, ventral thorax, croup and mane) were examined with a smartphone-attach...
Preventive health care and owner-reported disease prevalence of horses and ponies in Great Britain.
Research in veterinary science    June 13, 2013   Volume 95, Issue 2 418-424 doi: 10.1016/j.rvsc.2013.05.007
Ireland JL, Wylie CE, Collins SN, Verheyen KL, Newton JR.This study aimed to describe the provision of preventive health care and owner-reported disease prevalence in horses and ponies within Great Britain (GB), and to assess geographical variations in health care provision. A cross-sectional survey was conducted, using a postal questionnaire administered to a random sample of veterinary-registered owners of horses and ponies in GB (n=797). The majority of animals received regular preventive health care: 95.6% had regular hoof care; 71.3% were vaccinated for both influenza and tetanus and median time since last anthelmintic administration was 8.7 we...
BPV-1 infection is not confined to the dermis but also involves the epidermis of equine sarcoids.
Veterinary microbiology    December 23, 2010   Volume 150, Issue 1-2 35-40 doi: 10.1016/j.vetmic.2010.12.021
Brandt S, Tober R, Corteggio A, Burger S, Sabitzer S, Walter I, Kainzbauer C, Steinborn R, Nasir L, Borzacchiello G.In equids, bovine papillomaviruses of type 1 (BPV-1) and less frequently type 2 induce common, locally aggressive skin tumours termed sarcoids. Whereas BPV infection in cattle usually involves the epidermis and is productive in this skin layer, infection in equids is currently thought to be abortive, with virus solely residing as multiple episomes in dermal fibroblasts. Based on recent observations that do not agree with this assumption, we hypothesised that BPV also infects equid epidermis and is active in this skin layer. To test this hypothesis, we conducted a proof-of-principle study on ei...
Infectious entry of equine herpesvirus-1 into host cells through different endocytic pathways.
Virology    August 31, 2009   Volume 393, Issue 2 198-209 doi: 10.1016/j.virol.2009.07.032
Hasebe R, Sasaki M, Sawa H, Wada R, Umemura T, Kimura T.We investigated the mechanism by which equine herpesvirus-1 (EHV-1) enters primary cultured equine brain microvascular endothelial cells (EBMECs) and equine dermis (E. Derm) cells. EHV-1 colocalized with caveolin in EBMECs and the infection was greatly reduced by the expression of a dominant negative form of equine caveolin-1 (ecavY14F), suggesting that EHV-1 enters EBMECs via caveolar endocytosis. EHV-1 entry into E. Derm cells was significantly reduced by ATP depletion and treatments with lysosomotropic agents. Enveloped virions were detected from E. Derm cells by infectious virus recovery a...
Antifungal activity of tea tree oil from Melaleuca alternifolia against Trichophyton equinum: an in vivo assay.
Phytomedicine : international journal of phytotherapy and phytopharmacology    April 28, 2009   Volume 16, Issue 11 1056-1058 doi: 10.1016/j.phymed.2009.03.013
Pisseri F, Bertoli A, Nardoni S, Pinto L, Pistelli L, Guidi G, Mancianti F.Dermatophytes are a group of keratinophilic and keratinolytic molds, some of which are responsible for ringworm. Among them Trichophyton equinum, which mostly infects equids, can cause extensive outbreaks in stud farms. The conventional treatment of equine trichophytosis is topic, based upon medicated shampoos to reduce the spread of infection among the animals. Nevertheless the popularity of phytotherapy is at an all-time peak, and the interest for natural alternatives or complements to conventional drug therapy is challenging both in human and veterinary field. Among herbal remedia Tea Tree ...
Quantitative intradermal terbutaline sweat test in horses.
Equine veterinary journal    August 8, 2008   Volume 40, Issue 5 518-520 doi: 10.2746/042516408X322409
MacKay RJ.The aim of the current study was to quantify sweating responses to intradermal terbutaline in normal horses. Seven Thoroughbred horses were used. Terbutaline (10-fold dilutions from 1000-0.001 mg/l) and a saline control were injected intradermally (0.1 ml/site) and sweat collected for 30 min into absorbent pads taped over each injection site. Tests were performed monthly for 11 successive months and temperature, relative humidity and dewpoint were measured at the time of testing. There was no significant effect (P<or=0.05) of environmental variables or time of year on sweat responses at any...
Isolation of obligate anaerobic bacteria from ulcerative keratitis in domestic animals.
Veterinary ophthalmology    February 28, 2008   Volume 11, Issue 2 114-122 doi: 10.1111/j.1463-5224.2008.00610.x
Ledbetter EC, Scarlett JM.To determine the frequency of obligate anaerobic bacterial isolation from corneal samples of domestic animals with ulcerative keratitis and to characterize the historical, clinical, cytological, and microbiological features of culture-positive cases. Methods: Three hundred and thirty domestic animals with ulcerative keratitis. Methods: Anaerobic bacteriologic culture and Gram stain were performed on corneal samples from consecutive animals examined with suspect septic ulcerative keratitis. Additional corneal diagnostics included: aerobic bacteriologic culture for all species; fungal culture fo...
In vitro analysis of nonthermal plasma as a disinfecting agent.
American journal of veterinary research    December 6, 2006   Volume 67, Issue 12 2030-2035 doi: 10.2460/ajvr.67.12.2030
Watts AE, Fubini SL, Vernier-Singer M, Golkowski C, Shin S, Todhunter RJ.To determine the effect of nonthermal plasma on Staphylococcus aureus, fibroblasts in monolayer culture, and clean and contaminated skin explants. Methods: Normal skin from euthanized horses. Methods: S aureus organisms were plated and treated with nonthermal plasma followed by bacterial culture to assess viability. Fibroblasts in monolayer culture and the epidermal and dermal surfaces of clean and S aureus-contaminated skin explants were treated. The effects of distance and duration on the response to treatment were compared. Results: Compared with controls, treatment with nonthermal plasma r...
In vitro degradation of equine keratin by dermatophytes and other keratinophilic fungi.
Veterinary microbiology    December 27, 2005   Volume 114, Issue 3-4 352-358 doi: 10.1016/j.vetmic.2005.11.060
Apprich V, Spergser J, Rosengarten R, Stanek C.Keratinolytic properties of two dermatophytes (Microsporum gypseum, Trichophyton mentagrophytes) and three moulds (Scopulariopsis brevicaulis, Alternaria alternata, Geotrichum candidum) isolated from diseased equine hooves were examined to improve the understanding of pathogenic mechanisms leading to equine onychomycosis. Equine hoof horn material and skin, as well as hoof keratin and dermal keratin extracted from corresponding tissues, were used as sole carbon and nitrogen sources in five test tubes for each fungus. Within 18 days, supernatants of all tubes were repeatedly examined for kerati...
Dermatological and parasitological evaluation of infestations with chewing lice (Werneckiella equi) on horses and treatment using imidacloprid.
Parasitology research    June 7, 2005   Volume 97, Issue 1 7-12 doi: 10.1007/s00436-005-1379-6
Mencke N, Larsen KS, Eydal M, Sigurethsson H.Lice infestations in horses caused by the chewing louse Werneckiella (Damalinia) equi are observed worldwide. In the present study, the efficacy of 10% imidacloprid was tested on horses naturally infested with lice. Two groups of animals received a double application of 4 ml and 8 ml Advantage 10% spot-on on day 0 and 28 either. Horses, presenting dermatological signs with negative lice counts, were also included in this investigation. 40.86% of the horses presented positive lice counts and 84.21% of these animals showed clinical dermatologic signs. 65.45% of the lice-negative horses also show...
[Mycoses in domestic animals].
Revista iberoamericana de micologia    March 15, 2005   Volume 17, Issue 1 S2-S7 
García ME, Blanco JL.In the present paper we will present a general view of the main mycoses affecting domestic animals. In the dog, we show the importance of the dermatophytoses, increased by its zoonosic character and the problem of the false negatives in the traditional microbiological culture. Under the general term of systemic mycoses we include a series of conditions considered usually as aspergillosis, bat with more and more fungal species implicated as possible etiological agents. In addition, fungi, especially yeasts, are being implicated in canine otitis; in our laboratory 86 % of canine chronic otitis i...
Bacteria and fungi on the surface and within noninflamed hair follicles of skin biopsy specimens from horses with healthy skin or inflammatory dermatoses.
Veterinary dermatology    February 24, 2005   Volume 16, Issue 1 47-51 doi: 10.1111/j.1365-3164.2005.00417.x
Cook CP, Scott DW, Erb HN, Miller WH.A retrospective study using light microscopy was performed to assess the prevalence of surface and follicular bacteria and fungi in skin biopsy specimens from 247 horses with inflammatory dermatoses and from 27 horses with healthy skin. Cocci were found on the surface of specimens from 23% (95% confidence interval 18%, 29%) and 7% (95% confidence interval, 0%, 19%), respectively, of horses with skin disease and horses with healthy skin. Of the nine dermatoses with at least 10 cases in our series of horses, bacterial folliculitis had a higher prevalence of surface bacteria (57%; 95% confidence ...
The prevalence of apoptotic keratinocytes in equine epidermis: a retrospective light-microscopic study of skin-biopsy specimens from 253 horses with normal skin or inflammatory dermatoses.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine    December 22, 2004   Volume 51, Issue 9-10 400-404 doi: 10.1111/j.1439-0442.2004.00665.x
Macleod KD, Scott DW, Erb HN.A retrospective study was performed to assess the prevalence of apoptotic epidermal keratinocytes in biopsy specimens from 226 horses with inflammatory dermatoses and from 27 normal specimens. One or more apoptotic keratinocytes were found in specimens from 28 of 226 (12%) horses with various dermatoses, and in one of 27 (4%) specimens from normal horses. The prevalence (proportion of cases with apoptotic epidermal keratinocytes) of apoptotic keratinocytes in the group composed of discoid lupus erythematosus, erythema multiforme, photodermatitis, and systemic lupus erythematosus was significan...
Metastatic melanoma in horses.
Journal of veterinary internal medicine    July 27, 2002   Volume 16, Issue 4 452-456 doi: 10.1892/0891-6640(2002)0162.3.co;2
MacGillivray KC, Sweeney RW, Del Piero F.The clinical and pathologic findings are reviewed for 14 horses with metastatic melanoma. All were older gray horses, with an average age of 16 years. The most common sites of primary tumors were the ventral tail, perineum, and parotid salivary gland. Metastases were found in multiple locations and caused a variety of clinical syndromes. The most common sites for metastases were the lymph nodes, liver, spleen, skeletal muscle, lungs, and surrounding or within blood vessels throughout the body. Many of the horses had dermal melanomas for years (range 1-6 years) before succumbing to metastatic d...
Medical management of back pain.
The Veterinary clinics of North America. Equine practice    April 28, 1999   Volume 15, Issue 1 179-viii doi: 10.1016/s0749-0739(17)30171-2
Marks D.The most common causes of back pain and their medical treatment are discussed. These include: dermatologic problems and conditions resulting from saddle trauma; discomfort and stiffness owing to injured paraspinal muscles; pain associated with supraspinous ligament damage; osseous pain and nerve dysfunction related to the spine and sacroiliac area; and neurologic diseases that can manifest as back pain. Bitting problems, cervical pain, and coexisting lameness are also considered.
Inhibition by CaNa2EDTA of local tissue damage induced by Bothrops asper (terciopelo) venom: application in horse immunization for antivenom production.
Toxicon : official journal of the International Society on Toxinology    June 10, 1998   Volume 36, Issue 2 321-331 doi: 10.1016/s0041-0101(97)00114-1
León G, Estrada R, Chaves F, Rojas G, Ovadia M, Gutiérrez JM.The ability of the chelating agent CaNa2EDTA to inhibit local tissue damage induced by Bothrops asper venom was studied in mice and in horses used for polyvalent (Crotalinae) antivenom production. CaNa2EDTA was devoid of toxicity when injected i.m. or s.c. inducing only a mild edema. Preincubation of B. asper venom with CaNa2EDTA inhibited hemorrhagic and dermonecrotic activities, but did not reduce edema-forming and myotoxic effects. A group of horses initially immunized with native venoms developed less severe local tissue reactions when injected with booster doses of venom and CaNa2EDTA tha...
[Application possibilities of laser surgery in veterinary medicine. 3: Literature review and some case reports].
Tierarztliche Praxis    July 1, 1997   Volume 25, Issue 4 289-302 
Weigand K, Gerhards H, Köstlin R.The transmission of the laser beam trough flexible fibers enables an endoscopic application. Since this technique is minimal invasive and often does not require general anaesthesia there is an increasing interest in the use of laser techniques-for example in equine upper respiratory tract surgery. This paper gives a review about reported laser application in the different fields of veterinary surgery with emphasis on laser practice in dermatology, ophthalmology and endoscopic laser application.
Parasitic dermatoses that cause pruritus in horses.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 11-28 doi: 10.1016/s0749-0739(17)30328-0
Perris EE.Insect hypersensitivity is the most common cause of equine pruritus. It is a seasonal, highly pruritic dermatosis that is caused by the salivary antigens of biting insects. The most common insects are discussed in terms of the area of the horse affected, clinical signs, therapy, and preventative strategies.
Overview of equine pruritus.
The Veterinary clinics of North America. Equine practice    April 1, 1995   Volume 11, Issue 1 1-10 doi: 10.1016/s0749-0739(17)30327-9
Fadok VA.Pruritus is a common complaint associated with equine dermatoses. Self-mutilation results in alopecia, excoriations, scaling, and crusting; the aesthetic appearance of the horse is often ruined and the horse may be unfit for riding or showing. This article specifically addresses those pruritic dermatoses caused by allergies, including food allergy/intolerance, atopy and contact allergy, as well as by two ectoparasites, stick-tight fleas and rhabditic mange. The clinical signs, diagnostic tests, and treatment recommendations are discussed for each disorder. Insect hypersensitivity and pruritus ...
[Differential diagnosis of non-healing ‘fungal’patches in horses].
Tijdschrift voor diergeneeskunde    December 15, 1994   Volume 119, Issue 24 756-759 
Sloet van Oldruitenborgh-Oosterbaan MM, Klein WR, Misdorp W.Dermatophytosis is the most common equine skin disease. Mycotic-like lesions that do not disappear are suspected of being sarcoids. The clinical symptoms and therapeutic interventions for both affections are discussed. A short review of the differential diagnoses is presented.