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Topic:Diagnosis

Diagnosis in horses involves the systematic identification of diseases and conditions affecting equine health. This process relies on a combination of clinical evaluations, laboratory tests, imaging techniques, and other diagnostic tools to assess the health status of horses. Veterinarians utilize these methods to identify symptoms, determine the underlying causes of health issues, and formulate appropriate treatment plans. Diagnostic procedures in equine medicine can include blood tests, ultrasound, radiography, endoscopy, and more specialized tests such as genetic screening or advanced imaging modalities like MRI and CT scans. This page aggregates peer-reviewed research studies and scholarly articles that explore various diagnostic techniques, their applications, and advancements in the field of equine veterinary medicine.
Vascular hamartoma in horse limbs: presentation, diagnosis, and treatment of two case studies.
Veterinary research communications    November 15, 2024   Volume 49, Issue 1 8 doi: 10.1007/s11259-024-10601-y
Apolonio EVP, Gobbo LL, Woiblet NG, Dinau FC, Pyles MS, Ferrari LC, de Moura Alonso J, Alves ALG.Vascular hamartoma is an abnormal development of endothelial tissue that rarely affects horses. Histopathological examination remains the gold standard for definitive diagnosis, yet the presence of abnormal vascular structures must be carefully differentiated from other vascular anomalies and neoplasms. This report describes two cases of vascular proliferation affecting the skin on the lateral side over the left tarsus and the dorsolateral region over the fetlock joint of two fillies. The clinical history, presentation, and radiographic and sonographic findings in both patients suggested a neo...
Serum protein electrophoretic profile changes in West Nile virus-naturally infected horses.
Journal of equine veterinary science    November 14, 2024   105232 doi: 10.1016/j.jevs.2024.105232
Chaintoutis SC, Diakakis N, Polizopoulou ZS, Dovas CI.Serum protein electrophoresis (SPE) is widely used to evaluate protein changes associated with several pathologies, aiming to assist clinical diagnosis. This study aimed to determine, for the first time, SPE profile changes in WNV-naturally infected horses. Sixty horses with different clinical and infection status (encephalitis, asymptomatic infection, and immunologically naïve) were included. Total protein concentrations were determined via an automated biuret method and SPE was performed using a cellulose acetate membrane-based automated system. Statistical analysis revealed significantly h...
Plasma alpha-fetoprotein in neonatal foals affected by prematurity, sepsis and neonatal encephalopathy.
Journal of equine veterinary science    November 14, 2024   Volume 144 105231 doi: 10.1016/j.jevs.2024.105231
Lanci A, Ellero N, Castagnetti C, Perina F, Dondi F, Mariella J.Alpha-fetoprotein (AFP) concentrations have been reported in healthy foals and proposed as a biomarker of sepsis in foals born from mares with experimentally induced placentitis. This study aimed to describe the diagnostic and prognostic value of plasma AFP in foals spontaneously affected by different diseases. The study included all foals less than 72 h old that were diagnosed with either: (1) prematurity (PRE), when born prior to 320 days of gestation with immature physical characteristics; (2) sepsis (SEP), in the presence of both positive blood culture and SIRS or (3) neonatal encephalopat...
Validation of Vetscan Imagyst®, a diagnostic test utilizing an artificial intelligence deep learning algorithm, for detecting strongyles and Parascaris spp. in equine fecal samples.
Parasites & vectors    November 12, 2024   Volume 17, Issue 1 465 doi: 10.1186/s13071-024-06525-w
Steuer A, Fritzler J, Boggan S, Daniel I, Cowles B, Penn C, Goldstein R, Lin D.Current methods for obtaining fecal egg counts in horses are often inaccurate and variable depending on the analyst's skill and experience. Automated digital scanning of fecal sample slides integrated with analysis by an artificial intelligence (AI) algorithm is a viable, emerging alternative that can mitigate operator variation compared to conventional methods in companion animal fecal parasite diagnostics. Vetscan Imagyst is a novel fecal parasite detection system that uploads the scanned image to the cloud where proprietary software analyzes captured images for diagnostic recognition by a d...
Comparison Between Tracheal Wash and Bronchoalveolar Lavage Cytology for the Assessment of Exercise-Induced Pulmonary Hemorrhage (EIPH) in Racehorses.
Animals : an open access journal from MDPI    November 12, 2024   Volume 14, Issue 22 3243 doi: 10.3390/ani14223243
Bozzola C, Sala G, Schinardi L, Stancari G, Stucchi L, Ferrucci F, Zucca E.Exercise-Induced Pulmonary Hemorrhage (EIPH) is a common pulmonary disease among racehorses, diagnosed by the detection of blood in the trachea after strenuous exercise or the presence of hemosiderophages in the bronchoalveolar lavage fluid (BALF). Although the latter is considered the most sensitive method to diagnose EIPH, it is perceived as a less practical and more invasive procedure compared to tracheal wash (TW) collection among racehorse trainers. The present retrospective study aimed to verify the agreement between Tracheal wash and BALF cytology in assessing EIPH in racehorses. For th...
Visualization of anatomical structures in the carpal region of the horse using cone beam computed tomography in comparison with conventional multidetector computed tomography.
Frontiers in veterinary science    November 11, 2024   Volume 11 1431777 doi: 10.3389/fvets.2024.1431777
Hagenbach M, Bierau J, Cruz AM, Koch C, Manso-Díaz G, Büttner K, Staszyk C, Röcken M.In the diagnostics of orthopedic diseases in the horse, diagnostic imaging often plays a decisive role. Cone beam computed tomography (CBCT) imaging is used in both human and small animal medicine and becoming increasingly popular. To see whether CBCT imaging can be useful in the diagnosis of orthopedic diseases of the carpal region of the horse and to explore possible limitations we compared CBCT images with multidetector computed tomography (MDCT) images of the carpal region of equine cadaveric specimens. Unassigned: Twenty-eight forelimbs from fifteen horses, slaughtered for reasons unrelat...
Visualization of anatomical structures in the carpal region of the horse using cone beam computed tomography in comparison with conventional multidetector computed tomography.
Frontiers in veterinary science    November 11, 2024   Volume 11 1431777 doi: 10.3389/fvets.2024.1431777
Hagenbach M, Bierau J, Cruz AM, Koch C, Manso-Díaz G, Büttner K, Staszyk C, Röcken M.In the diagnostics of orthopedic diseases in the horse, diagnostic imaging often plays a decisive role. Cone beam computed tomography (CBCT) imaging is used in both human and small animal medicine and becoming increasingly popular. To see whether CBCT imaging can be useful in the diagnosis of orthopedic diseases of the carpal region of the horse and to explore possible limitations we compared CBCT images with multidetector computed tomography (MDCT) images of the carpal region of equine cadaveric specimens. Unassigned: Twenty-eight forelimbs from fifteen horses, slaughtered for reasons unrelat...
Hydroallantois in a mare associated with schistosomus and unilateral ovarian agenesis in the fetus.
Journal of equine veterinary science    November 10, 2024   Volume 144 105228 doi: 10.1016/j.jevs.2024.105228
Arroyo E, Whitelock LM, Stanton ME, Stevenson V, de Aguiar LH, Kelleman A.Hydropsical conditions in domestic animals are characterized by abnormal fluid accumulation. While their complete pathophysiology remains unclear, factors such as changes in chorioallantoic membranes, placentitis, or fetal abnormalities may contribute. Hydrops present as a medical emergency that can cause complications for the mare. Early diagnosis and treatment are crucial for the mare's prognosis, as fetal survival is often poor. This report describes a case of hydroallantois in a 9-year-old pregnant Quarter mare at 271 days of gestation, leading to dystocia of a non-viable foal with multipl...
Application of the horse grimace scale in horses with dental disease: Preliminary findings.
The Veterinary record    November 9, 2024   Volume 196, Issue 3 e4800 doi: 10.1002/vetr.4800
Sidwell AE, Duz M, Hill B, Freeman S, Hole SL.Dental disease is a common but often under-recognised condition in horses, possibly due to an inability to recognise clinical signs of oral discomfort. Some dental disorders are reportedly more painful than others, but there is no current metric by which dental pain can be objectively assessed. This study aimed to determine whether a facial expression-based pain scale offered an objective and reliable method for assessing dental pain in horses. It was hypothesised that dental disorders affecting the periodontium would produce high pain scores. Twelve horses with dental disease were evaluated f...
Diastasis of the Pubic Symphysis Without Fall While Horseback Riding: A Case Report.
Cureus    November 4, 2024   Volume 16, Issue 11 e72988 doi: 10.7759/cureus.72988
Giotis D, Konstantinidis C, Plakoutsis S, Vardakas D, Panagiotopoulos V.The purpose of this study was to demonstrate a rare case of pelvic ring injury in a healthy man without a history of high energy damage. A 43-year-old man presented to the emergency with local pain in pubic symphysis and difficulty walking after horseback riding. The patient did not report any fall or injury during this recreational activity, and apart from tachycardia, he was hemodynamically stable with normal blood pressure. Additionally, no deficit of neurological function was observed. The radiological imaging demonstrated an injury of the pelvic ring APC II with a diastasis of pubic symph...
Comparison of a customized glycemic pellets challenge with the oral sugar test to measure glycemic and insulinemic responses in horses.
Journal of veterinary internal medicine    October 28, 2024   Volume 38, Issue 6 3281-3287 doi: 10.1111/jvim.17191
Thane K, Sonntag J, Warnken T, Reiche D, Uricchio C, Frank N.Testing for insulin dysregulation (ID) in horses is commonly performed to guide management and therapeutic strategies. Objective: To evaluate a newly developed glycemic pellets challenge (GPC) and compare results to those obtained using the low-dose oral sugar test (OST). Methods: Twenty-four adult horses with unknown insulin status. Methods: A randomized crossover trial was performed. Horses underwent GPC (0.5 g glycemic carbohydrates/kg body weight) and OST (0.15 mL corn syrup/kg body weight) 7 days apart. Feed was withheld before testing and blood samples were collected at T0, T60, T1...
A first step towards objective grading of equine laryngeal function.
Veterinary journal (London, England : 1997)    October 26, 2024   Volume 308 106259 doi: 10.1016/j.tvjl.2024.106259
Hardwick J, Ahern B, Franklin S.Due to concerns about disagreement between veterinarians when grading resting laryngeal function (LF), a diagnostic decision tree (DDT) has been developed by codifying the Havemeyer grading system and objectively defining certain terms to remove ambiguity. Videoendoscopic examinations of the equine larynx that had previously been assigned a unanimous LF grade by 3 experienced observers were used to develop the DDT and determine the cut-off values. The DDT is a flow chart consisting of a series of dichotomous (yes/no) decisions, to dictate the order of decision making and direct the observer do...
Treatment of equine keratomycosis, part 1: selection of appropriate therapy based on clinical presentation and diagnostic testing improves clinical outcomes.
Journal of the American Veterinary Medical Association    October 23, 2024   1-11 doi: 10.2460/javma.24.06.0431
Smith HL, Love KR, Antezana A, Barr EM, Gilger BC, Oh A.To determine clinical outcome, treatment costs, and hospitalization duration in horses treated for keratomycosis and identify ophthalmic examination and diagnostic results associated with these outcomes. Methods: This was a retrospective study of 126 equine keratomycosis cases between 2004 and 2020 with fungal infection confirmed on cytology, culture, and/or histopathology and a minimum of 1-month follow-up. Details of the ophthalmic examination, diagnostic test results, and treatment and cost outcomes were recorded. Outcomes of interest were analyzed by treatment type. The relationship of pat...
Urinary incontinence and sabulous cystitis in mares: report of five cases.
Brazilian journal of veterinary medicine    October 21, 2024   Volume 46 e005024 doi: 10.29374/2527-2179.bjvm005024
de Melo UP, Ferreira C.This report describes five cases of urinary incontinence in Quarter Horse mares associated with the development of sabulous cystitis. The animals in this study had a history of persistent urinary incontinence for eight months, with clinical signs of continuous dribbling urine during rest and movement. The initial treatment with antibiotics and anti-inflammatory drugs was ineffective. Clinical examination revealed severe scalding in the perineal region and on the medial aspect of the hind limbs, along with neurological signs such as ataxia, hind limb paresis, and diminished perineal reflexes. T...
Isolated and multiple causes of equine dystocia.
Acta veterinaria Scandinavica    October 11, 2024   Volume 66, Issue 1 55 doi: 10.1186/s13028-024-00772-8
Ellerbrock M, Krohn J, Büttner K, Wehrend A.Dystocia is rare in horses, but is life-threatening for mares and foals. Therefore, veterinary research depends on up-to-date data to optimise equine dystocia management. In addition, knowledge of the prognosis of equine dystocia is necessary to advise animal owners. This retrospective study of equine dystocia aimed to enrich existing datasets with up-to-date information. For the first time, the focus was on the causes of dystocia that occurred alone or in combination. Over a period of 10 years, 72 cases of dystocia were analysed using a standardised, predetermined diagnosis code. Results: Of ...
Clinical insights: Current progress in multidisciplinary management of soft tissue surgical cases.
Equine veterinary journal    October 4, 2024   Volume 56, Issue 6 1088-1091 doi: 10.1111/evj.14417
Barnett T, Epstein K, Southwood L.No abstract available
Equine intraocular melanocytic neoplasia.
The Canadian veterinary journal = La revue veterinaire canadienne    October 2, 2024   Volume 65, Issue 10 1048-1054 
Labelle AL, Gemensky Metzler AM, McMullen RJ, Wiggans KT, Labelle P, Hamor RE.To describe the clinical appearance, histopathology, and treatment of equine intraocular melanocytic neoplasia in adult horses. Unassigned: A retrospective review of medical records was conducted. Data recorded included signalment, ocular examination findings, physical examination findings, therapeutic interventions, and case outcomes. Histopathologic characteristics of enucleated globes were evaluated. A Student's -test was used to evaluate differences in the interval from diagnosis to last known outcome between horses receiving therapeutic interventions and horses undergoing monitoring alone...
Concomitant melanoma and keratoma affecting the equine digit: clinical, pathological, and long-term follow-up findings.
BMC veterinary research    October 1, 2024   Volume 20, Issue 1 444 doi: 10.1186/s12917-024-04269-4
Bulnes F, Argüelles D, Buzón A, García-Álamo K, Rodríguez-Gómez IM, Hernández E, Mozos E.This case report details a long-term follow-up of a hoof melanoma with dermo-epidermal activity (resembling Spreading Superficial Melanoma (SSM)) in a bay horse with a history of a right front hoof keratoma. Melanomas involving the horse's foot are seldom reported and usually diagnosed as anaplastic melanomas based on signalment and post-mortem examination. The clinical-pathological characteristics of the foot melanoma in this bay horse are consistent with SSM-like described in humans, which is considered an intermediate malignant tumour attending their biological behaviour. However, a definit...
A multi-task learning model for clinically interpretable sesamoiditis grading.
Computers in biology and medicine    September 25, 2024   Volume 182 109179 doi: 10.1016/j.compbiomed.2024.109179
Guo L, Tahir AM, Hore M, Collins A, Rideout A, Wang ZJ.Sesamoiditis is a common equine disease with varying severity, leading to increased injury risks and performance degradation in horses. Accurate grading of sesamoiditis is crucial for effective treatment. Although deep learning-based approaches for grading sesamoiditis show promise, they remain underexplored and often lack clinical interpretability. To address this issue, we propose a novel, clinically interpretable multi-task learning model that integrates clinical knowledge with machine learning. The proposed model employs a dual-branch decoder to simultaneously perform sesamoiditis grading ...
Senecio ovatus poisoning in a horse – A case report.
Veterinarni medicina    September 22, 2024   Volume 69, Issue 9 329-336 doi: 10.17221/37/2024-VETMED
Kopecka A, Novotna T, Svobodova Z, Drabkova Z.This study describes a case of poisoning by pyrrolizidine alkaloids in a horse. To the best of the author's knowledge, this is the first confirmed case of Senecio ovatus poisoning. A six-year-old 450-kg Irish cob mare was presented to the Equine Clinic of the University of Veterinary Sciences Brno (Czechia) with symptoms of hepatic encephalopathy, which progressively worsened with time despite intensive therapy and led to euthanasia. A complex diagnostic and therapeutic approach including the post-mortem patoanatomical and histopathological examination is described here. Regar...
Quadricuspid aortic valve in a 16-year-old Quarter horse.
Journal of equine veterinary science    September 20, 2024   Volume 142 105199 doi: 10.1016/j.jevs.2024.105199
Caivano D, Cicogna M, Orvieto S, Spitale D, Porciello F.A 16-year-old horse, 400 kg, male, Quarter horse gelding was examined for a cardiac murmur that had not been previously heard. Physical examination revealed a regularly irregular pulse and a grade III/VI, decrescendo, diastolic murmur with a point of maximum intensity over the left heart base. Base-apex standard electrocardiographic examination at rest showed sinus rhythm with second-degree atrio-ventricular blocks. Echocardiography identified the presence of four aortic valve cusps, two equal larger and two unequal smaller cusps. Color flow Doppler examination showed a diastolic regurgitant j...
Disseminated pleomorphic rhabdomyosarcoma in a horse. Carpenter AL, Townsend KS, Johnson PJ, Kim DY.An 8-y-old National Show Horse mare was presented for evaluation of pneumonia and laminitis. Harsh bronchovesicular sounds were auscultated throughout both lung fields, and the mare had signs of moderately painful laminitis. Thoracic ultrasonography revealed lung consolidation throughout the dorsal aspect of both lungs, and radiography revealed an extensive diffuse-to-patchy bronchointerstitial lung pattern. The mare's clinical condition rapidly deteriorated, and euthanasia was elected. On postmortem examination, the lungs, omentum, spleen, liver, adrenal glands, kidneys, and femur contained 0...
Clinical variability of equine asthma phenotypes and analysis of diagnostic steps in phenotype differentiation.
Acta veterinaria Scandinavica    September 18, 2024   Volume 66, Issue 1 51 doi: 10.1186/s13028-024-00773-7
Meiseberg LK, Delarocque J, de Buhr N, Ohnesorge B.Equine asthma is a common, non-infectious, chronic lung disease that affects up to 80% of the horse population. Strict phenotyping and identification of subclinically asthmatic horses can be challenging. The aim of this study was to describe equine asthma phenotypes (mild, moderate, and severe asthma) defined by BALF cytology and occurrence of clinical signs in a population of privately owned horses and to identify the variables and examination steps with best discriminative potential. The standardised examination protocol included clinical examinations, blood work, airway endoscopy with bronc...
Survey of ocular abnormalities in a population of Turkmen horses.
Veterinary ophthalmology    September 16, 2024   Volume 28, Issue 4 741-746 doi: 10.1111/vop.13276
Faghihi H, Gharibi A, Ansari Mood M, Rajaei SM, Alavi SM.The aim of this study was to detect and describe ocular abnormalities in a population of Turkmen horses. Methods: A total of 55 Turkmen horses (33 mares and 22 stallions) from one herd were evaluated in this study. Methods: Demographic data (Age, Sex, Coat color) were recorded. All animals underwent complete ophthalmic examination. The Schirmer tear test -I (STT-I) was performed for all horses prior to other diagnostic tests. Neuro-ophthalmic examinations (menace response, dazzle reflex, pupillary light reflex, maze test, and visual tracking) were carried out in different lighting situations (...
Lameness and fever in a 3-year-old female English Thoroughbred horse.
Journal of the American Veterinary Medical Association    September 13, 2024   1-4 doi: 10.2460/javma.24.06.0426
Barbosa FMS, Santos IRD, Costa GG, Lopes CE, Pavarini SP, Driemeier D.No abstract available
In vitro evaluation of the automated hematology analyzer XN-31 for rapid diagnosis of equine piroplasmosis.
Microbiology spectrum    September 13, 2024   e0058224 doi: 10.1128/spectrum.00582-24
Ochi A, Toya Y, Sengoku M, Tsuchiya S, Kishi D, Ueno T.Equine piroplasmosis (EP) is a protozoal disease affecting equids, caused by and . EP is conventionally diagnosed using microscopic, molecular, and/or serological methods, which are time-consuming. Consequently, there is a need for faster testing methods. In this study, we evaluated the application of the Sysmex XN-31 automated hematology analyzer, originally a rapid test for detecting malaria in humans, for the diagnosis of EP. The cultured parasites were measured using the XN-31 that had been customized for horse blood samples (XN-31m). The following parameters were evaluated: limit of dete...
Treatment of a urethral stricture by image-guided placement of a custom-made absorbable stent in a standing, sedated horse.
Journal of veterinary internal medicine    September 12, 2024   Volume 38, Issue 5 2795-2800 doi: 10.1111/jvim.17181
Baltrimaite M, Kearney C, O'Brien A, Duggan M, Cuq B.A 10-year-old Irish Sport Horse gelding developed complications from a general anesthesia resulting in sling support and recurrent urinary catheterization. The horse subsequently presented signs of dysuria and pollakiuria, was diagnosed with sabulous cystitis, and developed a urethral stricture from the repeated catheterizations, which was confirmed on urethroscopy. Clinical signs persisted despite conservative management with topical corticosteroids and urethral bougienage with balloon dilators. An image-guided approach was used to treat the stricture with a custom-made polydioxanone stent pl...
Unusual Equine Tumors.
The Veterinary clinics of North America. Equine practice    September 11, 2024   S0749-0739(24)00073-7 doi: 10.1016/j.cveq.2024.07.014
Fintl C, Wilkins PA.There are a number of unusual tumors in the horse. Gross tumor characteristics, anatomical location, and signalment may assist with identification. Clinical pathology is often unrewarding with non-specific findings, while fine needle aspirates may not obtain sufficient tissue material to confirm a diagnosis. Although regular staining of biopsy material may be sufficient, immunohistochemistry markers may be required, especially in less differentiated tumors. The prognosis is dependent on the type, location, tumor size as well as on metastatic spread. A selection of unusual and rare tumors that ...
Equine Melanoma Updates.
The Veterinary clinics of North America. Equine practice    September 11, 2024   Volume 40, Issue 3 431-439 doi: 10.1016/j.cveq.2024.07.008
Hollis AR.Melanomas are very common in older gray horses, with 80% of gray horses having at least 1 melanoma by 15 years of age. Historically considered a benign disease, it is now known that up to 66% of lesions will eventually metastasize. Melanomas may also cause local problems due to abscessation, ulceration, and interference with function of the affected areas. Treatment can be limited by size and location, but surgical resection, where possible, is likely to be the treatment of choice.
Diagnosis and Staging of Equine Neoplasia.
The Veterinary clinics of North America. Equine practice    September 11, 2024   S0749-0739(24)00051-8 doi: 10.1016/j.cveq.2024.07.002
Johns I, Bryan J.The diagnosis of neoplasia in the horse is both simple and extremely challenging, depending on the type of neoplasm and its location. Obtaining an accurate diagnosis of a neoplastic condition is key to formulating an appropriate treatment plan if possible or developing a palliative plan if curative treatment options do not exist. A combination of historical features, clinical examination findings, and diagnostic testing typically allow a working diagnosis of neoplasia to be made, with a definitive diagnosis requiring the identification of neoplastic cells in a sample or tissue.
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