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Topic:Diagnostic Imaging

Diagnostic imaging in horses encompasses a range of techniques used to visualize the internal structures of the equine body for the purpose of diagnosis and treatment planning. These techniques include radiography, ultrasonography, magnetic resonance imaging (MRI), computed tomography (CT), and nuclear scintigraphy. Each modality offers unique advantages in assessing different tissues and conditions, such as bone fractures, soft tissue injuries, and joint abnormalities. Radiography is commonly employed for evaluating bone structures, while ultrasonography is frequently used for soft tissue assessment. MRI and CT provide detailed cross-sectional images, facilitating the examination of complex anatomical regions. Nuclear scintigraphy can detect areas of increased bone activity, often used in lameness evaluations. This page compiles peer-reviewed research studies and scholarly articles that explore the applications, advancements, and comparative effectiveness of diagnostic imaging modalities in equine veterinary practice.
Bilateral testicular mixed germ cell-sex cord-stromal tumours in a stallion.
Reproduction in domestic animals = Zuchthygiene    November 13, 2008   Volume 44, Issue 5 846-851 doi: 10.1111/j.1439-0531.2008.01090.x
Brito LF, Engiles JB, Turner RM, Getman LM, Ebling A.An 18-year-old Friesian stallion was examined approximately one week after reportedly presenting scrotal swelling due to torsion of the spermatic cords. Upon presentation no scrotal swelling was noted, the testes were normally oriented, and no abnormalities of the spermatic cords were noted. However, both testes were smaller than expected for a mature stallion and deep palpation revealed that the consistency of the testes was nodular. Ultrasonographic evaluation of the testes revealed diffuse heterogeneous parenchyma with multiple hypoechoic nodular areas. Grossly, the testicular parenchyma wa...
[The horse as an athlete: an animal model of choice for sports medicine: sonographic studies of joint disorders].
Bulletin de l\'Academie nationale de medecine    September 30, 2008   Volume 192, Issue 3 521-540 
Denoix JM.Equine diagnostic sonography was initially used for the diagnosis and documentation of tendon injuries. Since 1990, this technique, along with radiography, has become an indispensable imaging procedure for the diagnosis of equine joint injuries. Sonography provides precise diagnostic information on the synovial membrane and fluid, the articular cartilage, subchondral bone and joint margins, the ligaments and menisci, and the anatomical structures involved in periarticular swelling or enlargement. Improvements in ultrasound machines and better superficial and deep image resolution allow us to e...
Correlation of quantitative computed tomographic subchondral bone density and ash density in horses.
Bone    September 19, 2008   Volume 44, Issue 2 316-319 doi: 10.1016/j.bone.2008.08.129
Drum MG, Les CM, Park RD, Norrdin RW, McIlwraith CW, Kawcak CE.The purpose of this study was to compare subchondral bone density obtained using quantitative computed tomography with ash density values from intact equine joints, and to determine if there are measurable anatomic variations in mean subchondral bone density. Five adult equine metacarpophalangeal joints were scanned with computed tomography (CT), disarticulated, and four 1-cm(3) regions of interest (ROI) cut from the distal third metacarpal bone. Bone cubes were ashed, and percent mineralization and ash density were recorded. Three-dimensional models were created of the distal third metacarpal...
Changes in subchondral bone mineral density and collagen matrix organization in growing horses.
Bone    August 13, 2008   Volume 43, Issue 6 1108-1114 doi: 10.1016/j.bone.2008.07.254
Holopainen JT, Brama PA, Halmesmäki E, Harjula T, Tuukkanen J, van Weeren PR, Helminen HJ, Hyttinen MM.The effects of growth and maturation on the mineral deposition and the collagen framework of equine subchondral bone (SCB) were studied. Methods: Osteochondral specimens (diameter 6 mm) from the left metacarpophalangeal joint of 5-(n=8), 11-(n=8) and 18-month-old (n=6) horses were investigated at two differently loaded sites (Site 1 (S1): intermittent peak loading; Site 2 (S2): habitual loading). The SCB mineral density (BMD) was measured with peripheral quantitative computer tomography (pQCT), and the data were adjusted against the volume fraction (Vv) of the bone extracellular matrix (ECM). ...
Brainstem auditory-evoked responses in horses with temporohyoid osteoarthropathy.
Journal of veterinary internal medicine    August 4, 2008   Volume 22, Issue 5 1196-1202 doi: 10.1111/j.1939-1676.2008.0158.x
Aleman M, Puchalski SM, Williams DC, Kass PH, Holliday TA.Facial and vestibulocochlear nerve dysfunction occurs commonly in horses with temporohyoid osteoarthropathy (THO); however, auditory dysfunction has not been thoroughly assessed. Objective: To determine if auditory abnormalities occur in horses with THO. Methods: Eleven diseased and 8 control horses. Methods: This is a prospective study in which brainstem auditory-evoked responses (BAER) were recorded in 11 horses diagnosed with THO through neurologic, endoscopic, radiographic, or computed tomographic examinations. BAER findings were compared with those recorded from 8 adult control horses. Re...
Exophthalmus secondary to a sinonasal cyst in a horse.
Journal of the American Veterinary Medical Association    July 17, 2008   Volume 233, Issue 2 285-288 doi: 10.2460/javma.233.2.285
Annear MJ, Gemensky-Metzler AJ, Elce YA, Stone SG.A 13-year-old female Miniature Horse was evaluated for progressive unilateral exophthalmia of the left globe of 3 weeks' duration. Results: Results of a physical examination were unremarkable. Ophthalmic examination identified exophthalmus of the left globe with complete resistance to retropulsion and mild blepharoconjunctivitis. Computed tomography revealed a large, space-occupying mass within the left caudal maxillary and left conchofrontal sinuses. The mass extended into the left retrobulbar space and contacted the cribriform plate. Trephination yielded copious amounts of turbid yellow flui...
Novel optical imaging technique to determine the 3-D orientation of collagen fibers in cartilage: variable-incidence angle polarization-sensitive optical coherence tomography.
Osteoarthritis and cartilage    July 14, 2008   Volume 17, Issue 1 33-42 doi: 10.1016/j.joca.2008.05.005
Ugryumova N, Jacobs J, Bonesi M, Matcher SJ.To investigate a novel optical method to determine the three dimensional (3-D) structure of articular cartilage collagen non-destructively. Methods: Polarization-sensitive optical coherence tomography was used to determine the apparent optical birefringence of articular cartilage for a number of different illumination directions. A quantitative method based on the theory of light propagation in uniaxial crystalline materials was validated on equine flexor tendon. Qualitative maps of fiber polar and azimuthal orientation at sites on the posterior and anterior segments of the equine third metaca...
Quantitative analysis of scintigraphic findings in tibial stress fractures in Thoroughbred racehorses.
American journal of veterinary research    July 3, 2008   Volume 69, Issue 7 886-890 doi: 10.2460/ajvr.69.7.886
Valdés-Martínez A, Seiler G, Mai W, Bolt DM, Mudge M, Dukti SA, Hubert JD.To develop a quantitative method of interpreting tibial scintigrams of Thoroughbred racehorses with tibial stress fractures that may facilitate diagnosis of fractures and to provide prognostic information regarding future performance of affected horses. Methods: 35 Thoroughbred racehorses. Methods: Static bone-phase scintigrams of tibial stress fractures were quantitatively analyzed by use of ratios of the mean radionuclide counts per pixel in a region of interest (ROI) drawn around the area of increased uptake of radiopharmaceutical to mean counts per pixel in a second ROI drawn around an app...
Comparison of mean bone densities of three preparations of the distal portion of the equine third metacarpal bone measured by use of quantitative computed tomography.
American journal of veterinary research    July 3, 2008   Volume 69, Issue 7 891-893 doi: 10.2460/ajvr.69.7.891
Drum MG, Les CM, Park RD, McIlwraith CW, Kawcak CE.To evaluate whether cutting equine subchondral bone to demarcate specific regions of interest (ROIs) influences the mean density for that bone as measured via quantitative computed tomography (QCT). Sample population-2 metacarpophalangeal joints from equine cadavers. Methods: The distal portion of the third metacarpal bone of each intact metacarpophalangeal joint was scanned via CT to simulate in vivo conditions. Each joint was subsequently disarticulated and dissected, and the distal portion of the dissected third metacarpal bone in air was scanned. Then, six 1-cm(2) areas representing ROIs w...
Desmitis of the distal digital annular ligament in seven horses: MRI diagnosis and surgical treatment.
Veterinary surgery : VS    June 20, 2008   Volume 37, Issue 4 336-344 doi: 10.1111/j.1532-950X.2008.00386.x
Cohen JM, Schneider RK, Zubrod CJ, Sampson SN, Tucker RL.(1) To describe the clinical signs and abnormalities observed on magnetic resonance imaging (MRI) in 7 horses with desmitis of the distal digital annular ligament (DDAL); (2) to describe the normal magnetic resonance (MR) appearance and thickness of the DDAL in health; and (3) to describe a tenoscopic surgical technique for treating horses with desmitis of the DDAL. Methods: Retrospective study. Methods: Horses (n=7) with desmitis of the DDAL. Methods: MR examinations of 20 sound horses were reviewed to determine the normal appearance of the DDAL. Dimensions obtained from these images were com...
Ultrasonographic diagnosis–idiopathic muscular hypertrophy of the small intestine in a miniature horse. Dechant JE, Whitcomb MB, Magdesian KG.No abstract available
Gastrointestinal ultrasonography in normal adult ponies. Epstein K, Short D, Parente E, Reef V, Southwood L.The objective of this study was to determine the characteristics based on ultrasonographic examination of the stomach, duodenum, jejunum, cecum, and peritoneal fluid in normal adult ponies. Abdominal ultrasonographic examination was performed in nine unsedated standing ponies. The duodenum was examined at three sites and the jejunum in 12 regions. Wall thickness, contractility, distention, and luminal contents were recorded. Stomach wall thickness and location, cecal wall thickness, and peritoneal fluid location and character were recorded. Statistical analysis was performed. Wall thicknesses ...
What is your diagnosis? Pleural fluid from a neonatal Thoroughbred filly with pneumonia.
Veterinary clinical pathology    June 7, 2008   Volume 37, Issue 2 237-241 doi: 10.1111/j.1939-165X.2008.00021.x
Stokol T, Gold J, Johnson A, Ainsworth D.A 3-day-old filly was presented to the Cornell University Hospital for Animals with an umbilical hematoma and mild aspiration pneumonia. The foal underwent abdominal surgery for resection of the hematoma. Recovery was uneventful, but 3 days after surgery, the foal became progressively tachypneic. Imaging studies revealed bilateral pleural effusion and pleuropneumonia. Cytologic evaluation and bacterial culture of the pleural fluid from both sides of the chest revealed sterile exudates, consisting mostly of neutrophils, with fewer macrophages and lymphocytes. Pleural fluid macrophages contained...
Evaluation of three methods for measurement of hemoglobin and calculated hemoglobin parameters with the ADVIA 2120 and ADVIA 120 in dogs, cats, and horses.
Veterinary clinical pathology    June 7, 2008   Volume 37, Issue 2 173-179 doi: 10.1111/j.1939-165X.2008.00039.x
Bauer N, Moritz A.Besides flow cytometric detection of cellular hemoglobin (HGB) concentration, the ADVIA 2120 uses a novel cyanide-free colorimetric method to determine extracellular total HGB concentration. In human samples, the results are equivalent to those of the cyanmethemoglobin method on the ADVIA 120. Cyanide-free HGB measurement has not been evaluated in animal samples. Objective: The aim of this prospective study was to compare the 3 methods of HGB analysis on the ADVIA 2120 and ADVIA 120 in blood samples from dogs, cats, and horses. Methods: Consecutive fresh K(3)EDTA blood samples from 119 dogs, 1...
Simulation of turbulent airflow using a CT based upper airway model of a racehorse.
Journal of biomechanical engineering    June 6, 2008   Volume 130, Issue 3 031011 doi: 10.1115/1.2913338
Rakesh V, Datta AK, Ducharme NG, Pease AP.Computational model for airflow through the upper airway of a horse was developed. Previous flow models for human airway do not hold true for horses due to significant differences in anatomy and the high Reynolds number of flow in the equine airway. Moreover, models that simulate the entire respiratory cycle and emphasize on pressures inside the airway in relation to various anatomical diseases are lacking. The geometry of the airway was created by reconstructing images obtained from computed tomography scans of a thoroughbred racehorse. Different geometries for inhalation and exhalation were ...
Clinical and scintigraphic findings in horses with a bone fragility disorder: 16 cases (1980-2006).
Journal of the American Veterinary Medical Association    June 4, 2008   Volume 232, Issue 11 1694-1699 doi: 10.2460/javma.232.11.1694
Anderson JD, Galuppo LD, Barr BC, Puchalski SM, Macdonald MM, Whitcomb MB, Magdesian KG, Stover SM.To describe clinical and scintigraphic abnormalities in horses with a bone fragility disorder. Methods: Retrospective case series. Methods: 16 horses with scintigraphic evidence of multiple sites of increased radiopharmaceutical uptake (IRU). Procedures-Medical records were reviewed for information on signalment; history; clinical, clinicopathologic, and diagnostic imaging findings; and treatment. Follow-up information was obtained through telephone interviews with owners. Results: Horses ranged from 4 to 22 years old; there were 8 castrated males and 8 females. Foci of IRU most commonly invol...
Use of multichannel electrointestinography for noninvasive assessment of myoelectrical activity in the cecum and large colon of horses.
American journal of veterinary research    June 4, 2008   Volume 69, Issue 6 709-715 doi: 10.2460/ajvr.69.6.709
Koenig JB, Martin CE, Nykamp SG, Mintchev MP.To evaluate whether changes in myoelectrical activity in the cecum and large colon of horses can be detected via multichannel electrointestinography (EIG). Methods: 6 healthy mature horses. Methods: Each horse underwent 3 EIG procedures. Intestinal myoelectrical activity (cecum and large colon) was recorded during a 20-minute period following i.v. administration of physiologic saline (0.9% NaCl) solution (20 mL; baseline), erythromycin lactobionate (0.5 mg/kg), or detomidine (0.015 mg/kg); intestinal contractions were concurrently viewed via B-mode ultrasonography. By use of computer software,...
Novel oblique radiographic projection of the temporomandibular articulation of horses.
The Veterinary record    June 3, 2008   Volume 162, Issue 22 714-716 doi: 10.1136/vr.162.22.714
Ramzan PH, Marr CM, Meehan J, Thompson A.A novel radiographic projection is described for assessing part of the temporomandibular articulation of horses. It minimises the superimposition of osseous structures of the cranium that limit the usefulness of conventional projections and permits improved imaging in cases of suspected disease.
Effects of exercise vs experimental osteoarthritis on imaging outcomes.
Osteoarthritis and cartilage    May 27, 2008   Volume 16, Issue 12 1519-1525 doi: 10.1016/j.joca.2008.04.015
Kawcak CE, Frisbie DD, Werpy NM, Park RD, McIlwraith CW.To identify changes in imaging outcomes in a controlled model of osteoarthritis (OA) vs exercise. Methods: Sixteen 2-year-old horses were randomly assigned to an exercise control (n=8) or an exercise OA (n=8) group. All horses had middle carpal joints arthroscopically explored and an osteochondral fragment was induced in one middle carpal joint of the OA group. All horses were treadmill exercised for the duration of the study (91 days). Clinical, radiographic, nuclear scintigraphic, computed tomographic and magnetic resonance imaging (MRI) examinations were performed and outcomes of these were...
The collateral ligaments of the distal interphalangeal joint: magnetic resonance imaging and post mortem observations in 25 lame and 12 control horses.
Equine veterinary journal    May 20, 2008   Volume 40, Issue 6 538-544 doi: 10.2746/042516408X313661
Dyson S, Blunden T, Murray R.Magnetic resonance imaging (MRI) is used with increasing frequency to diagnose injuries of the collateral ligaments (CLs) of the distal interphalangeal (DIP) joint, but the results have not been verified by histology and the mechanism of injury is poorly understood. Objective: Abnormal signal intensity and tissue contour represents change in tissue structure detected on histology. Objective: To compare results in horses free from and those with chronic lameness and to describe possible progression of lesions. Methods: One or both feet of horses free from lameness (Group N: n = 12) and with foo...
Diagnostic imaging of the equine fetlock region using radiography and ultrasonography. Part 2: the bony disorders.
Veterinary journal (London, England : 1997)    May 7, 2008   Volume 181, Issue 2 123-136 doi: 10.1016/j.tvjl.2008.01.017
Vanderperren K, Saunders JH.The metacarpophangeal/metatarsophalangeal (fetlock) joint in the horse is commonly associated with equine lameness and diagnostic imaging is routinely used to investigate disorders of the joint and its surrounding tissues. This review describes the osseous disorders of the fetlock as well as the technical aspects of taking radiographic and ultrasonographic images of the different lesions. In current clinical practice, a combination of radiography and ultrasonography is still the most frequently used approach to arrive at a diagnosis.
A comparison of recovery times and characteristics with sevoflurane and isoflurane anaesthesia in horses undergoing magnetic resonance imaging.
Veterinary anaesthesia and analgesia    May 5, 2008   Volume 35, Issue 5 383-391 doi: 10.1111/j.1467-2995.2008.00399.x
Leece EA, Corletto F, Brearley JC.To compare recovery times and quality following maintenance of anaesthesia with sevoflurane or isoflurane after a standard intravenous induction technique in horses undergoing magnetic resonance imaging (MRI). Methods: Prospective, randomised, blinded clinical study. Animals One hundred ASA I/II horses undergoing MRI. Methods: Pre-anaesthetic medication with intravenous acepromazine and romifidine was followed by induction of anaesthesia with diazepam and ketamine. The animals were randomised into two groups to receive either sevoflurane or isoflurane in oxygen. Horses were subjectively scored...
Ultrasound-guided balloon thrombectomy for treatment of aorto-iliac-femoral thrombosis in a horse.
Journal of veterinary internal medicine    May 2, 2008   Volume 22, Issue 3 679-683 doi: 10.1111/j.1939-1676.2008.0095.x
Hilton H, Aleman M, Textor J, Nieto J, Pevec W.No abstract available
Evaluation of computed tomographic anatomy of the equine metacarpophalangeal joint.
American journal of veterinary research    May 2, 2008   Volume 69, Issue 5 631-638 doi: 10.2460/ajvr.69.5.631
Vanderperren K, Ghaye B, Snaps FR, Saunders JH.To determine the detailed computed tomography (CT) anatomy of the metacarpophalangeal (MCP) joint in healthy horses. Methods: 10 cadaveric forelimbs from 10 adult horses without orthopedic disease. Methods: CT of the MCP joint was performed on 4 forelimbs. In 1 of the limbs, CT was also performed after intra-articular injection of 30 mL of contrast medium (40 mg of iodine/mL). Transverse slices 1-mm thick were obtained, and sagittal and dorsal planes were reformatted with a slice thickness of 2 mm. The CT images were matched with corresponding anatomic slices from 6 additional forelimbs. Resul...
Evaluation of technetium Tc 99m-labeled biotin for scintigraphic detection of soft tissue inflammation in horses.
American journal of veterinary research    May 2, 2008   Volume 69, Issue 5 639-646 doi: 10.2460/ajvr.69.5.639
Kleine LG, Solano M, Rusckowski M, Hunt KE, Johnson KL, Kirker-Head CA.To evaluate the use of technetium Tc 99m-labeled EDTA-biotin monomer ((99m)Tc-EB1) as a scintigraphic imaging agent for soft tissue inflammatory lesions in horses. Methods: 6 healthy adult horses. Methods: First (phase 1), the agent's safety and blood-tissue clearance and an appropriate imaging protocol were determined in 6 horses. Each horse was injected with (99m)Tc-EB1 (1.1 GBq, IV, once); images were acquired at intervals during the following 24-hour period. Subsequently (phase 2), inflammation was induced via injection of 200 mg (10 mL) of mepivacaine (0.4 mg/kg) into the right neck muscu...
Options for treatment of cecocolic intussusception in horses.
Journal of the American Veterinary Medical Association    April 30, 2008   Volume 232, Issue 8 1134 
Freeman DE.No abstract available
Diagnostic imaging of the equine fetlock region using radiography and ultrasonography. Part 1: Soft tissues.
Veterinary journal (London, England : 1997)    April 28, 2008   Volume 181, Issue 2 111-122 doi: 10.1016/j.tvjl.2008.03.005
Vanderperren K, Saunders JH.The equine fetlock is the joint most commonly associated with lameness. Although the fetlock is regarded as a simple joint, diagnosis of a fetlock disorder can be a challenge and various imaging modalities are routinely used to arrive at an accurate diagnosis. This review describes the principal disorders affecting the soft tissues of the fetlock region and addresses some of the technical aspects involved in taking radiographic and ultrasonographic images of the different soft tissue lesions. A combination of radiography and ultrasonography is still the most commonly used diagnostic approach i...
Ultrasonographic characteristics (cross-sectional area and relative echogenicity) of the digital flexor tendons and ligaments of the metacarpal region in Purebred Spanish horses.
Veterinary journal (London, England : 1997)    April 8, 2008   Volume 180, Issue 3 377-383 doi: 10.1016/j.tvjl.2008.01.012
Agut A, Martínez ML, Sánchez-Valverde MA, Soler M, Rodríguez MJ.The objectives of this study were to establish normal values for relative echogenicity (RE) and cross-sectional area (CSA) of the flexor tendons and ligaments of the metacarpal region of Purebred Spanish horses (PBSH), and to determine the effect of body mass index (BMI), age, sex and forelimb on these variables. Transverse ultrasonographic images were obtained using 20 normal PBSH (10 females, 10 males; 2-25 years of age; BMI 132.04-152.25; not in training). The images were digitised and values for CSA and RE were determined for each structure. The suspensory ligament was the most echogenic a...
Measurement of equine laminar blood flow and vascular permeability by use of dynamic contrast-enhanced computed tomography.
American journal of veterinary research    March 4, 2008   Volume 69, Issue 3 371-377 doi: 10.2460/ajvr.69.3.371
Kruger EF, Puchalski SM, Pollard RE, Galuppo LD, Hornof WJ, Wisner ER.To define the reference range for laminar blood flow (BF) and vascular permeability (VPM) in horses without laminitis by use of dynamic contrast-enhanced computed tomography (CT). Methods: 9 adult horses that were not lame and had no abnormalities of the laminae or phalanges detectable via radiographic examination. Methods: Each horse was anesthetized by use of a routine protocol. Horses were placed in right or left lateral recumbency with the dependent forelimb in the CT gantry; only 1 limb of each horse was scanned. Serial 10-mm collimated transverse CT images were acquired at the same locat...
Less invasive techniques for equine fracture repair and arthrodesis.
The Veterinary clinics of North America. Equine practice    March 4, 2008   Volume 24, Issue 1 177-189 doi: 10.1016/j.cveq.2007.11.004
Richardson DW.To repair equine fractures successfully, surgeons traditionally have done aggressive open approaches with maximal internal fixation to achieve adequate stability and comfort. Although the need for stability is unquestionable, newer technologies and imaging modalities have allowed improvement in the biology of internal fixation in selected fractures and arthrodeses.
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