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Topic:Disease control

Disease control in horses encompasses the strategies and measures implemented to prevent, manage, and eradicate infectious and non-infectious diseases within equine populations. This field involves the study of pathogen transmission, host-pathogen interactions, and the development of effective vaccination and biosecurity protocols. Disease control also includes monitoring and surveillance of equine health to identify outbreaks and implement timely interventions. Key aspects of disease control in horses involve understanding the epidemiology of equine diseases, improving diagnostic techniques, and enhancing treatment options. This page compiles peer-reviewed research studies and scholarly articles that explore various methodologies, technologies, and practices aimed at controlling diseases in horses, with a focus on improving overall equine health and welfare.
3-D technology used to accurately understand equine ileocolonic aganglionosis.
Cells, tissues, organs    July 25, 2013   Volume 198, Issue 2 160-168 doi: 10.1159/000353218
Muniz E, Lobo Ladd AA, Lobo Ladd FV, da Silva AA, Kmit FV, Borges AS, Teixeira R, da Mota LS, Belli CB, de Zoppa AL, da Silva LC, de Melo MP, Coppi AA.Ileocolonic aganglionosis (ICA) is the congenital and hereditary absence of neurons that constitute the enteric nervous system and has been described in various species including humans - Hirschsprung's disease - and horses - overo lethal white syndrome (OLWS). Hirschsprung's disease affects circa 1 in 5,000 live births. At best, this disease means an inability to absorb nutrients from food (humans). At worse, in horses, it always means death. Despite our general understanding of the functional mechanisms underlying ICA, there is a paucity of reliable quantitative information about the structu...
Vesicular stomatitis outbreak in the southwestern United States, 2012. McCluskey BJ, Pelzel-McCluskey AM, Creekmore L, Schiltz J.Vesicular stomatitis is a viral disease primarily affecting horses and cattle when it occurs in the United States. Outbreaks in the southwestern United States occur sporadically, with initial cases typically occurring in Texas, New Mexico, or Arizona and subsequent cases occurring in a northward progression. The viruses causing vesicular stomatitis can be transmitted by direct contact of lesioned animals with other susceptible animals, but transmission is primarily through arthropod vectors. In 2012, an outbreak of vesicular stomatitis in the United States occurred that was caused by Vesicular...
A questionnaire study of equine gastrointestinal parasite control in Scotland.
Equine veterinary journal    July 23, 2013   Volume 46, Issue 1 25-31 doi: 10.1111/evj.12101
Stratford CH, Lester HE, Morgan ER, Pickles KJ, Relf V, McGorum BC, Matthews JB.Anthelmintic resistance in equine gastrointestinal nematodes is a threat to equine health and welfare. Detailed knowledge of anthelmintic use and parasite control methods is a prerequisite to identification of potential risk factors for resistance. Objective: To identify parasite control practices employed by equine owners in Scotland and investigate management factors associated with anthelmintic resistance. Methods: Questionnaire study of equine parasite control in Scotland. Methods: Questionnaires were available electronically, distributed at a conference and mailed to clients. Key areas ex...
Identification of hotspots in the European union for the introduction of four zoonotic arboviroses by live animal trade.
PloS one    July 23, 2013   Volume 8, Issue 7 e70000 doi: 10.1371/journal.pone.0070000
Durand B, Lecollinet S, Beck C, Martínez-López B, Balenghien T, Chevalier V.Live animal trade is considered a major mode of introduction of viruses from enzootic foci into disease-free areas. Due to societal and behavioural changes, some wild animal species may nowadays be considered as pet species. The species diversity of animals involved in international trade is thus increasing. This could benefit pathogens that have a broad host range such as arboviruses. The objective of this study was to analyze the risk posed by live animal imports for the introduction, in the European Union (EU), of four arboviruses that affect human and horses: Eastern and Western equine enc...
Pathogenesis of Venezuelan equine encephalitis.
Veterinary microbiology    July 22, 2013   Volume 167, Issue 1-2 145-150 doi: 10.1016/j.vetmic.2013.07.012
Taylor KG, Paessler S.Equine encephalids have high mortality rates and represent a significant zoonotic public health threat. Of these the most pathogenic viruses to equids are the alphaviruses in the family Togaviridae. The focus of this review Venezualen equine encephalitis virus (VEEV) has caused the most widespread and recent epidemic outbreaks of disease. Circulation in naturally occuring rodent-mosquito cycles, results in viral spread to both human and equine populations. However, equines develop a high titer viremia and can transmit the virus back to mosquito populations. As such, the early recognition and c...
Sero-surveillance of equine infectious anemia virus in equines in India during more than a decade (1999-2012).
Indian journal of virology : an official organ of Indian Virological Society    July 16, 2013   Volume 24, Issue 3 386-390 doi: 10.1007/s13337-013-0142-3
Malik P, Singha H, Goyal SK, Khurana SK, Kumar R, Virmani N, Shanmugasundaram K, Pandey SB, Kant R, Singh BK, Singh RK.Equine infectious anemia (EIA) is a retroviral infection of horses. Horses infected by EIA virus (EIAV) become inapparent carriers that remain asymptomatic for the remainder of their life span and serve as infection source to other horses. In this study, agar gel immunodiffusion test and ELISA were used to investigate the presence of antibodies to EIAV in equines. A total of 67,042 equine serum samples from 19 states and two union territories were tested during April 1999 to September 2012. The results revealed that none of the animals were positive for antibodies to EIAV from 1999 to December...
Focus on: African horse sickness.
The Veterinary record    July 9, 2013   Volume 173, Issue 1 13-14 doi: 10.1136/vr.f4250
Hopley R, Toth B.No abstract available
Equine disease surveillance: quarterly summary.
The Veterinary record    July 9, 2013   Volume 173, Issue 1 11-13 doi: 10.1136/vr.f4254
No abstract available
Identification of novel immunoreactive proteins of Streptococcus zooepidemicus with potential as vaccine components.
Vaccine    July 8, 2013   Volume 31, Issue 38 4129-4135 doi: 10.1016/j.vaccine.2013.06.100
Velineni S, Timoney JF.Streptococcus zooepidemicus is an important opportunistic pathogen of the equine respiratory and reproductive tracts. A normal tonsillar and mucosal commensal, it becomes invasive under conditions of stress such as virus infection, weaning, high temperature, prolonged transportation and failure of uterine involution. The aim of this study was to evaluate the vaccine potential of several surface exposed and secreted proteins of a novel mucoid clone of SzNC78 (ST-307) from an epizootic of equine respiratory disease. Methods: An expression gene library of SzNC78 was probed with a pool of convales...
Surveillance of equine influenza viruses through the RESPE network in France from November 2005 to October 2010.
Equine veterinary journal    July 8, 2013   Volume 45, Issue 6 776-783 doi: 10.1111/evj.12100
Legrand LJ, Pitel PH, Marcillaud-Pitel CJ, Cullinane AA, Couroucé AM, Fortier GD, Freymuth FL, Pronost SL.The Réseau d'Epidémio-Surveillance en Pathologie Equine (RESPE, the French epidemiological network for equine diseases) is a network for epidemio-surveillance of major equine diseases based around sentry veterinarians in France. Objective: The aim of this study was to evaluate the contribution of RESPE to efficient surveillance of equine influenza virus (EIV) in France. Methods: Retrospective cross-sectional study. Methods: From November 2005 to October 2010, epidemiological and phylogenetic studies were performed on 1426 nasopharyngeal swabs received at the Frank Duncombe Laboratory. Detect...
Crisis communication. Horse industry working on better response to disease outbreaks.
Journal of the American Veterinary Medical Association    July 5, 2013   Volume 242, Issue 11 1461-1462 
Larkin M.No abstract available
Differential expression of three members of the multidomain adhesion CCp family in Babesia bigemina, Babesia bovis and Theileria equi.
PloS one    July 3, 2013   Volume 8, Issue 7 e67765 doi: 10.1371/journal.pone.0067765
Bastos RG, Suarez CE, Laughery JM, Johnson WC, Ueti MW, Knowles DP.Members of the CCp protein family have been previously described to be expressed on gametocytes of apicomplexan Plasmodium parasites. Knocking out Plasmodium CCp genes blocks the development of the parasite in the mosquito vector, making the CCp proteins potential targets for the development of a transmission-blocking vaccine. Apicomplexans Babesia bovis and Babesia bigemina are the causative agents of bovine babesiosis, and apicomplexan Theileria equi causes equine piroplasmosis. Bovine babesiosis and equine piroplasmosis are the most economically important parasite diseases that affect world...
Potential of a sequence-based antigenic distance measure to indicate equine influenza vaccine strain efficacy.
Vaccine    July 2, 2013   Volume 31, Issue 51 6043-6045 doi: 10.1016/j.vaccine.2013.06.070
Daly JM, Elton D.The calculation of p(epitope) values, a sequence-based measure of antigenic distance between strains, was developed for human influenza. The potential to apply the p(epitope) value to equine influenza vaccine strain selection was assessed. There was a negative correlation between p(epitope) value and vaccine efficacy for pairs of vaccine and challenge strains used in cross-protection studies in ponies that just reached statistical significance (p=0.046) only if one pair of viruses was excluded from the analysis. Thus the p(epitope) value has potential to provide additional data to consider in ...
Equine grass sickness in Scotland: a case-control study of signalment- and meteorology-related risk factors.
Equine veterinary journal    June 28, 2013   Volume 46, Issue 1 64-71 doi: 10.1111/evj.12077
Wylie CE, Shaw DJ, Fordyce FM, Lilly A, McGorum BC.Equine grass sickness (EGS) remains a frequently fatal disease of equids in Britain. Since previous investigations of signalment- and meteorology-related risk factors for EGS have yielded some conflicting data, further investigation is warranted. Objective: To identify signalment- and meteorology-related risk factors for EGS in Scotland. Methods: Retrospective time-matched case-control study. Methods: This study was undertaken using data for 455 EGS cases and 910 time-matched controls that were referred to the Royal (Dick) School of Veterinary Studies, and average UK Meteorological Office weat...
Northern Ireland disease surveillance, January to March 2013.
The Veterinary record    June 26, 2013   Volume 172, Issue 25 657-658 doi: 10.1136/vr.f3577
No abstract available
[The Horse Symptom Prevention Packet (Triple P): a preventive membership in the horse husbandry].
Tijdschrift voor diergeneeskunde    June 22, 2013   Volume 138, Issue 5 301-303 
Steenbergen M.No abstract available
First evidence of autochthonous cases of Leishmania (Leishmania) infantum in horse (Equus caballus) in the Americas and mixed infection of Leishmania infantum and Leishmania (Viannia) braziliensis.
Veterinary parasitology    June 20, 2013   Volume 197, Issue 3-4 665-669 doi: 10.1016/j.vetpar.2013.06.014
Soares IR, Silva SO, Moreira FM, Prado LG, Fantini P, Maranhão Rde P, da Silva Filho JM, Melo MN, Palhares MS.This study reports the first evidence of infection by Leishmania infantum in Equus caballus in Americas and the first mixed infection of L. infantum/Leishmania braziliensis on this mammalian species in the world. The diagnoses was based on presence of parasites in lesions and bone marrow aspirates, their identification by using specific primers for L. infantum and L. braziliensis complexes and also serological methods IFAT and ELISA. The analysis of the PCR products suggested mixed infection in three animals. Further studies involving equine leishmaniasis are carrying out in order to clarify t...
Amblyomma cajennense infestation on horses in two microregions of the state of Rio de Janeiro, Brazil. Pires MS, Santos TM, Santos HA, Vilela JA, Peixoto MP, Roier EC, Silva CB, Barreira JD, Lemos ER, Massard CL.The objective of this study was to evaluate factors associated with infestation by Amblyomma cajennense on horses in two microregions of the state of Rio de Janeiro. Horses on 62 farms in the municipalities of the Itaguaí and Serrana microregions were evaluated between January and May 2009. The animals were examined to determine the presence of ticks and infestation level. The animals' rearing and management were assessed on each farm property using an epidemiological questionnaire. Out of the 635 horses evaluated, 41.6% were infested with A. cajennense. It was observed that farms in low-alti...
Equine gammaherpesviruses: perfect parasites?
Veterinary microbiology    June 19, 2013   Volume 167, Issue 1-2 86-92 doi: 10.1016/j.vetmic.2013.05.031
Hartley CA, Dynon KJ, Mekuria ZH, El-Hage CM, Holloway SA, Gilkerson JR.The evolutionary success of the equine gammaherpesviruses (GHVs) is demonstrated by their consistent and widespread presence in horse populations worldwide. Equine GHVs establish infection in young foals and can be continually detected over the lifetime of the host either by recrudescence of latent infections or by re-infection. A definitive diagnosis of clinical disease in horses due to GHV infection remains challenging given the ubiquitous nature of the GHVs in horses without clinical signs, as well as in horses with clinical signs ranging from mild respiratory disease to severe equine multi...
Envelope determinants of equine lentiviral vaccine protection.
PloS one    June 13, 2013   Volume 8, Issue 6 e66093 doi: 10.1371/journal.pone.0066093
Craigo JK, Ezzelarab C, Cook SJ, Chong L, Horohov D, Issel CJ, Montelaro RC.Lentiviral envelope (Env) antigenic variation and associated immune evasion present major obstacles to vaccine development. The concept that Env is a critical determinant for vaccine efficacy is well accepted, however defined correlates of protection associated with Env variation have yet to be determined. We reported an attenuated equine infectious anemia virus (EIAV) vaccine study that directly examined the effect of lentiviral Env sequence variation on vaccine efficacy. The study identified a significant, inverse, linear correlation between vaccine efficacy and increasing divergence of the ...
Anthelmintic efficacy against cyathostomins in horses in Southern England.
Veterinary parasitology    June 10, 2013   Volume 197, Issue 1-2 189-196 doi: 10.1016/j.vetpar.2013.06.009
Lester HE, Spanton J, Stratford CH, Bartley DJ, Morgan ER, Hodgkinson JE, Coumbe K, Mair T, Swan B, Lemon G, Cookson R, Matthews JB.Cyathostomins are considered to be the most important group of helminths to affect equids due to their high prevalence, potential pathogenicity and ability to develop anthelmintic resistance. Their control relies almost exclusively on frequent anthelmintic use. Currently, fenbendazole (FBZ), pyrantel embonate (PYR), ivermectin (IVM) and moxidectin (MOX) are licensed for use in horses in the UK. With no new anthelmintics likely to be licensed in the near future, it is essential that investigations into the efficacy of current anthelmintics in different locations are performed to help inform con...
Biosecurity at equestrian competitions: Olympic legacy?
Equine veterinary journal    June 7, 2013   Volume 45, Issue 4 396-397 doi: 10.1111/evj.12055
Slater J.No abstract available
Worms’ adaptation a critical problem: anthelmintic resistance a problem in ruminants, horses.
Journal of the American Veterinary Medical Association    June 6, 2013   Volume 242, Issue 9 1198-1200 
Cima G.No abstract available
UK horse passport rules–‘a catalogue of misunderstanding’.
The Veterinary record    June 5, 2013   Volume 172, Issue 22 571 doi: 10.1136/vr.f3488
No abstract available
Can Theileria equi be eliminated from carrier horses?
Veterinary journal (London, England : 1997)    June 2, 2013   Volume 196, Issue 3 279 doi: 10.1016/j.tvjl.2013.03.016
Butler C.No abstract available
Identification of immuno-dominant antigens of Trypanosoma evansi for detection of chronic trypanosomosis using experimentally infected equines.
Research in veterinary science    May 25, 2013   Volume 95, Issue 2 522-528 doi: 10.1016/j.rvsc.2013.04.030
Yadav SC, Kumar R, Kumar V, Jaideep , Kumar R, Gupta AK, Bera BC, Tatu U.Trypanosoma evansi is the most extensively distributed trypanosome responsible for disease called surra in livestock in many countries including frequent outbreaks in India. The prevalence of this disease is most commonly reported by standard parasitological detection methods (SPDM); however, antibody ELISA is being in practice by locally produced whole cell lysate (WCL) antigens in many countries. In the present investigation, we attempted to identify and purify immuno dominant, infection specific trypanosome antigens from T. evansi proteome using experimentally infected equine serum by immun...
Descriptive epidemiology of African horse sickness in Zimbabwe.
The Onderstepoort journal of veterinary research    May 24, 2013   Volume 80, Issue 1 578 doi: 10.4102/ojvr.v80i1.578
Gordon S, Bolwell C, Rogers C, Guthrie A, Magunda F, Hove P.A study of the prevalence of African horse sickness in horses was conducted, using records from two private equine practices in Harare for the period 1998-2004. Results indicated a higher prevalence of the disease in horses in Zimbabwe in the late rainy season (March - May). Age of the horse was found to be a significant risk factor, with foals or yearlings appearing to be 1.80 times more likely to contract the disease compared with horses older than two years. The case fatality rate in foals or yearlings was also higher than in older age groups, but this difference was not significant. The va...
Rapid, simple and sensitive detection of Q fever by loop-mediated isothermal amplification of the htpAB gene.
PLoS neglected tropical diseases    May 16, 2013   Volume 7, Issue 5 e2231 doi: 10.1371/journal.pntd.0002231
Pan L, Zhang L, Fan D, Zhang X, Liu H, Lu Q, Xu Q.Q fever is the most widespread zoonosis, and domestic animals are the most common sources of transmission. It is not only difficult to distinguish from other febrile diseases because of the lack of specific clinical manifestations in humans, but it is also difficult to identify the disease in C. burnetii-carrying animals because of the lack of identifiable features. Conventional serodiagnosis requires sera from the acute and convalescent stages of infection, which are unavailable at early diagnosis. Nested PCR and real-time PCR require equipment. In this study, we developed a Loop-Mediated Iso...
An investigation of anthelmintic efficacy against strongyles on equine yards in Scotland.
Equine veterinary journal    May 15, 2013   Volume 46, Issue 1 17-24 doi: 10.1111/evj.12079
Stratford CH, Lester HE, Pickles KJ, McGorum BC, Matthews JB.Cyathostomins comprise 50 helminth species, considered the most problematic equine endoparasites. Three classes of anthelmintic are currently licensed for their control, namely the benzimidazoles (fenbendazole), tetrahydropyrimidines (pyrantel) and macrocyclic lactones (ivermectin and moxidectin). Anthelmintic resistance in cyathostomins is common. With no new classes expected in the near future, it is essential to determine the efficacy of the available anthelmintics to inform future control programmes. Objective: To determine the efficacy of all 3 anthelmintic classes against strongyles in e...
Osteochondral repair: evaluation with sweep imaging with fourier transform in an equine model.
Radiology    May 14, 2013   Volume 269, Issue 1 113-121 doi: 10.1148/radiol.13121433
Rautiainen J, Lehto LJ, Tiitu V, Kiekara O, Pulkkinen H, Brünott A, van Weeren R, Brommer H, Brama PA, Ellermann J, Kiviranta I, Nieminen MT....To evaluate the status of articular cartilage and bone in an equine model of spontaneous repair by using the sweep imaging with Fourier transform (SWIFT) magnetic resonance (MR) imaging technique. Methods: Experiments were approved by the Utrecht University Animal Ethics Committee. Six-millimeter-diameter chondral (n = 5) and osteochondral (n = 5, 3-4 mm deep into subchondral bone) defects were created in the intercarpal joints of seven 2-year-old horses and examined with SWIFT at 9.4 T after spontaneous healing for 12 months. Conventional T2 maps and gradient-echo images were obtained for com...
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