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Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Risk and protective factors of Leishmaniasis in the rural area of the western border region of Rio Grande do Sul, Brazil.
BMC veterinary research    October 14, 2021   Volume 17, Issue 1 330 doi: 10.1186/s12917-021-03021-6
Pradella GD, Duarte CA, Escobar TA, Zuravski L, Góss GC, Skupien JA, Lübeck I.The Leishmaniases are on the top of the global list of tropical neglected diseases. The number of infected dogs in South America is estimated in millions and correlated to disease cases in humans, especially in Brazil. Equines may get infected too and can play a role in the epidemiological chain. Thus, the aim of the present study was to evaluate risk and protective factors of leishmaniasis in rural areas of the western border region of Rio Grande do Sul state, Brazil by Leishmania spp. protozoa molecular detection and serological evaluation (ELISA) in equine and canine blood samples. This wor...
Nasal high flow oxygen therapy in hospitalised neonatal foals.
Equine veterinary journal    October 13, 2021   Volume 54, Issue 5 946-951 doi: 10.1111/evj.13515
Floyd E, Danks S, Comyn I, Mackenzie C, Marr CM.Respiratory disease is common in critically ill neonatal foals. Traditional oxygen therapy (TOT) with nasal insufflation of oxygen is often used to provide first-line respiratory support. Mechanical ventilation is used in foals which require a greater level of support but requires specialist expertise and can be associated with significant complications. Non-invasive ventilation (NIV) enables a greater level of respiratory support without the need for intubation. High flow oxygen therapy (HFOT) is a mode of NIV commonly used in human intensive care. Objective: To describe the use of HFOT in ho...
Duplication of blaCTX-M-1 and a class 1 integron on the chromosome enhances antimicrobial resistance in Escherichia coli isolated from racehorses in Japan.
Journal of global antimicrobial resistance    October 13, 2021   Volume 27 225-227 doi: 10.1016/j.jgar.2021.10.004
Tamamura-Andoh Y, Niwa H, Kinoshita Y, Uchida-Fujii E, Arai N, Watanabe-Yanai A, Iwata T, Akiba M, Kusumoto M.Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae have become a cause for great concern. Although some studies have reported the prevalence of ESBL-producing bacteria and ESBL-encoding genes in horses worldwide, the genetic structure surrounding the ESBL gene has not been analysed in detail. In the present study, we isolated two ESBL-producing Escherichia coli strains from diseased racehorses in Japan and demonstrated the mechanisms underlying the acquisition of their antimicrobial resistance (AMR) genes. Two ESBL-producing E. coli strains (E148 and E189) were isolated from th...
Clinical insights: Equine herpesvirus myeloencephalopathy: The conundrum of vaccination in performance and leisure horses.
Equine veterinary journal    October 7, 2021   Volume 53, Issue 6 1088-1090 doi: 10.1111/evj.13509
Kydd JH.No abstract available
Clinical insights: Assisted reproductive techniques: More than a solution to subfertility?
Equine veterinary journal    October 7, 2021   Volume 53, Issue 6 1084-1087 doi: 10.1111/evj.13510
Stout TAE, Griffiths H.No abstract available
Anthelmintic resistance: is a solution possible?
Experimental parasitology    October 7, 2021   Volume 230 108169 doi: 10.1016/j.exppara.2021.108169
Ahuir-Baraja AE, Cibot F, Llobat L, Garijo MM.More than 50 years after anthelmintic resistance was first identified, its prevalence and impact on the animal production industry continues to increase across the world. The term "anthelmintic resistance" (AR) can be briefly defined as the reduction in efficacy of a certain dose of anthelmintic drugs (AH) in eliminating the presence of a parasite population that was previously susceptible. The main aim of this study is to examine anthelmintic resistance in domestic herbivores. There are numerous factors playing a role in the development of AR, but the most important is livestock management. T...
First outbreak of glanders in Nepal and possible implications for the animal sector.
Transboundary and emerging diseases    October 6, 2021   Volume 68, Issue 6 3015-3017 doi: 10.1111/tbed.14338
Acharya KP, Marahatta S, Wilson RT.No abstract available
A retrospective study of twin pregnancy management in mares.
Theriogenology    October 1, 2021   Volume 176 183-187 doi: 10.1016/j.theriogenology.2021.09.018
Raś A, Raś-Noryńska M.The aim of the study was to compare three methods of reducing twin pregnancy in mares to maintain a single pregnancy. As multiple pregnancies in mare are always undesirable, early ultrasound diagnosis makes possible management of twin pregnancies and extra embryo removal. In years 2010-2018, 16494 mares were sonographically tested for early pregnancy, finding 868 cases of twins (471 bilateral and 397 unilateral). 260 mares with a confirmed bilateral tween pregnancy were subjected to manual crushing of one embryo and administration of flunixin at a dose of 1.1 mg/kg BW. 186 mares were subjecte...
A Survey of Control Strategies for Equine Small Strongyles in Lithuania.
Helminthologia    September 30, 2021   Volume 58, Issue 3 225-232 doi: 10.2478/helm-2021-0031
Dauparaitė E, Kupčinskas T, Hoglund J, Petkevičius S.Anthelmintic resistance (AR) in equine cyathostomins is being reported all over the world. In Lithuania, however, the last study on this subject was published more than fifteen years ago, thus little is known about the current situation. The aim of this study was to determine the factors that may associated with the development of AR on equine studs in Lithuania. A questionnaire containing seven open-ended and nine closed multiple-choice questions about worm control strategies, use of anthelmintic substances and stable management practices was posted to 71 randomly selected horse establishment...
Surveillance of strangles in UK horses between 2015 and 2019 based on laboratory detection of Streptococcus equi.
The Veterinary record    September 27, 2021   Volume 189, Issue 12 e948 doi: 10.1002/vetr.948
McGlennon A, Waller A, Verheyen K, Slater J, Grewar J, Aanensen D, Newton R.Previously national surveillance data for monitoring strangles (Streptococcus equi infection) in UK horses was limited. Improved awareness and knowledge of positive diagnoses would permit the optimisation of biosecurity protocols, decreasing the prevalence of strangles. Methods: Seven UK laboratories reported positive strangles diagnoses between 1 January 2015 and 31 December 2019 based on identifying Streptococcus equi via agent detection assays from field-based practitioner-submitted samples. Associated clinical history and animal signalment were collected where provided, and descriptive ana...
Abstracts of the 11th International Equine Infectious Diseases Conference, 27th September – 1st October 2021.
Equine veterinary journal    September 25, 2021   Volume 53 Suppl 56 9-83 doi: 10.1111/evj.13495
No abstract available
A Systematic Review of Musculoskeletal Mobilization and Manipulation Techniques Used in Veterinary Medicine.
Animals : an open access journal from MDPI    September 24, 2021   Volume 11, Issue 10 2787 doi: 10.3390/ani11102787
Haussler KK, Hesbach AL, Romano L, Goff L, Bergh A.Mobilization and manipulation techniques are often used in small animal and equine practice; however, questions remain concerning indications, dosing and efficacy. A bibliographic search was performed to identify peer-reviewed publications from 1980 to 2020 that evaluated the clinical effects of musculoskeletal mobilization and manipulation techniques in dogs, cats and horses. The search strategy identified 883 papers for review. Inclusion and exclusion criteria were applied. The clinical indications, dosages, outcome parameters, and reported efficacy within each publication were recorded and ...
Infrarenal aortic reconstruction using autologous femoral vein for a mycotic aneurysm caused by Streptococcus equi.
Journal of surgical case reports    September 14, 2021   Volume 2021, Issue 9 rjab388 doi: 10.1093/jscr/rjab388
Ghaly P, Di Mascio D, Vicaretti M.A common source of infection in equine, , is an uncommon pathogen in humans, rarely identified as the cause for mycotic aortic aneurysms. Typically associated with consumption of unpasteurized milk or contact with horses, can result in severe bacteremia, endocarditis and meningitis. We describe the presentation and successful management of a 69-year-old retired equestrian who underwent infrarenal aortic resection and reconstruction using autologous right femoral vein for a mycotic aneurysm.
Equine disease surveillance: quarterly update.
The Veterinary record    September 11, 2021   Volume 189, Issue 5 e904 doi: 10.1002/vetr.904
No abstract available
Management of an EHV-1 outbreak at FEI events and its international impact.
The Veterinary record    September 11, 2021   Volume 189, Issue 5 e905 doi: 10.1002/vetr.905
Caterina Termine, Göran Akerström and Gonçalo Paixão of the Fédération Equestre Internationale's Veterinary Department describe the management of an outbreak of neurological equine herpesvirus 1 that affected a number of international showjumping events in Europe earlier this year.
Exercise-induced airflow changes in horses with asthma measured by electrical impedance tomography.
Journal of veterinary internal medicine    September 10, 2021   Volume 35, Issue 5 2500-2510 doi: 10.1111/jvim.16260
Herteman N, Mosing M, Waldmann AD, Gerber V, Schoster A.Equine asthma (EA) causes airflow impairment, which increases in severity with exercise. Electrical impedance tomography (EIT) is an imaging technique that can detect airflow changes in standing healthy horses during a histamine provocation test. Objective: To explore EIT-calculated flow variables before and after exercise in healthy horses and horses with mild-to-moderate (MEA) and severe equine asthma (SEA). Methods: Nine healthy horses 9 horses diagnosed with MEA and 5 with SEA were prospectively included. Methods: Recordings were performed before and after 15 minutes of lunging. Absolute...
Practical Review of the Management of Animal Bites.
Plastic and reconstructive surgery. Global open    September 9, 2021   Volume 9, Issue 9 e3778 doi: 10.1097/GOX.0000000000003778
Savu AN, Schoenbrunner AR, Politi R, Janis JE.Animal bites are common worldwide. Due to the plethora of animals, there are diverse pathogens with specific associated risks and treatment algorithms. It is crucial to understand these to develop and execute appropriate management plans. This practical review was designed to amalgamate the most common bites worldwide and synthesize data to help guide treatment plans. Methods: A PubMed literature search was performed focusing on the major animal bites. High-level studies were preferred and analyzed but lower-level studies were also used if high-level studies did not exist. Results: The tables ...
Hereditary Equine Regional Dermal Asthenia homozygote adult working horse with mild signs – A Case Report.
Journal of equine veterinary science    September 6, 2021   Volume 106 103756 doi: 10.1016/j.jevs.2021.103756
Patterson Rosa L, Troop TW, Martin K, Vierra M, Foster G, Lundquist E, Brooks SA, Lafayette C.Hereditary Equine Regional Dermal Asthenia (HERDA) is an autosomal recessive condition present in the American Quarter Horse and other related breeds. Resulting from a mutation in the peptidyl-prolyl cis-trans isomerase B (PPIB) gene, HERDA is homologous to Ehlers-Danlos syndrome in humans. Characterized by fragile, hyperelastic, skin, HERDA affected horses often present first with slow-healing wounds usually on the dorsum, and resulting in atrophic scars, seromas, and ulcers. As there is no treatment for the condition affected horses are typically reported to be unrideable, and if persisten...
Gut Microbiota Manipulation in Foals-Naturopathic Diarrhea Management, or Unsubstantiated Folly?
Pathogens (Basel, Switzerland)    September 4, 2021   Volume 10, Issue 9 doi: 10.3390/pathogens10091137
Goodman-Davis R, Figurska M, Cywinska A.Diarrhea in foals is a problem of significant clinical and economic consequence, and there are good reasons to believe microbiota manipulation can play an important role in its management. However, given the dynamic development of the foal microbiota and its importance in health and disease, any prophylactic or therapeutic efforts to alter its composition should be evidence based. The few clinical trials of probiotic preparations conducted in foals to date show underwhelming evidence of efficacy and a demonstrated potential to aggravate rather than mitigate diarrhea. Furthermore, recent studie...
Challenges in navigating molecular diagnostics for common equine respiratory viruses.
Veterinary journal (London, England : 1997)    September 3, 2021   Volume 276 105746 doi: 10.1016/j.tvjl.2021.105746
Pusterla N, Leutenegger CM, Barnum S, Wademan C, Hodzic E.Equine respiratory viruses remain a leading cause of equine morbidity and mortality, with the resurgence of certain infections, an increasing population of elderly, more susceptible horses, the growth of international equine commerce, and an expansion in geographic distribution of pathogens. The focus of rapid diagnosis of infectious diseases has also shifted recently, with the appearance and increasing importance of nucleic acid amplification-based techniques, primarily polymerase chain reaction (PCR), at the expense of traditional methods such as clinical microbiology. While PCR is fast, rel...
[Remodeling in equine asthma - Effects of antigen avoidance and pharmacological therapy].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere    September 1, 2021   Volume 49, Issue 5 320-325 doi: 10.1055/a-1581-6231
Barton AK, Gehlen H.The term remodeling describes the process resulting in a tissue that is structurally and architecturally altered compared to its healthy counterpart. At least in severe equine asthma, this occurs mainly, but not exclusively, as a consequence of neutrophilic airway inflammation and is characterized by hypertrophy of the smooth muscle layers in airway and arterial walls as well as fibrosis of the bronchial walls and pulmonary interstitial tissue. To date, much less is known for mild to moderate equine asthma. For a long time it was assumed that these processes are irreversible, and at least for ...
Effectiveness of Abbott BinaxNOW Rapid Antigen Test for Detection of SARS-CoV-2 Infections in Outbreak among Horse Racetrack Workers, California, USA.
Emerging infectious diseases    September 1, 2021   Volume 27, Issue 11 2761-2767 doi: 10.3201/eid2711.211449
Surasi K, Cummings KJ, Hanson C, Morris MK, Salas M, Seftel D, Ortiz L, Thilakaratne R, Stainken C, Wadford DA.The Abbott BinaxNOW rapid antigen test is cheaper and faster than real-time reverse transcription PCR (rRT-PCR) for detecting severe acute respiratory syndrome coronavirus 2. We compared BinaxNOW with rRT-PCR in 769 paired specimens from 342 persons during a coronavirus disease outbreak among horse racetrack workers in California, USA. We found positive percent agreement was 43.3% (95% CI 34.6%-52.4%), negative percent agreement 100% (95% CI 99.4%-100%), positive predictive value 100% (95% CI 93.5%-100%), and negative predictive value 89.9% (95% CI 87.5%-92.0%). Among 127 rRT-PCR-positive ...
The First Report of Genetic Polymorphisms of the Equine SPRN Gene in Outbred Horses, Jeju and Halla Horses.
Animals : an open access journal from MDPI    September 1, 2021   Volume 11, Issue 9 2574 doi: 10.3390/ani11092574
Won SY, Kim YC, Do K, Jeong BH.Prion disease is a fatal infectious disease caused by the accumulation of pathogenic prion protein (PrP) in several mammals. However, to date, prion disease has not been reported in horses. The Sho protein encoded by the shadow of the prion protein gene (SPRN) plays an essential role in the pathomechanism of prion diseases. To date, the only genetic study of the equine SPRN gene has been reported in the inbred horse, Thoroughbred horse. We first discovered four SPRN single nucleotide polymorphisms (SNPs) in 141 Jeju and 88 Halla horses by direct DNA sequencing. In addition, we found that the g...
Prevalence of anthelmintic resistant cyathostomins in Prince Edward Island, Canada.
Veterinary parasitology, regional studies and reports    August 30, 2021   Volume 26 100629 doi: 10.1016/j.vprsr.2021.100629
Butler AJ, Greenbank H, Parrish R, Nielsen MK, Stoughton WB.Cyathostomins are the most common parasites of adult horses worldwide. Currently, the three classes of anthelmintics used to treat cyathostomin infections includes benzimidazoles, pyrimidines and macrocyclic lactones. However, due to widespread overuse, cyathostomins have developed varying degrees of resistance to all classes of anthelmintics. Fecal egg count reduction tests (FECRT) are currently used to determine the presence of anthelmintic resistance (AR), while egg reappearance periods (ERP) are used to investigate early macrocyclic lactone resistance. The objective of this study was to in...
Global epidemiology of Equine Influenza viruses; “A possible emerging zoonotic threat in future” an extensive systematic review with evidence.
Brazilian journal of biology = Revista brasleira de biologia    August 27, 2021   Volume 83 e246591 doi: 10.1590/1519-6984.246591
Khan A, Mushtaq MH, Muhammad J, Ahmed B, Khan EA, Khan A, Zakki SA, Altaf E, Haq I, Saleem A, Warraich MA, Ahmed N, Rabaan AA.There are different opinions around the World regarding the zoonotic capability of H3N8 equine influenza viruses. In this report, we have tried to summarize the findings of different research and review articles from Chinese, English, and Mongolian Scientific Literature reporting the evidence for equine influenza virus infections in human beings. Different search engines i.e. CNKI, PubMed, ProQuest, Chongqing Database, Mongol Med, and Web of Knowledge yielded 926 articles, of which 32 articles met the inclusion criteria for this review. Analyzing the epidemiological and Phylogenetic data from ...
Molecular Detection and Phylogenetic Analysis of Tick-Borne Pathogens in Ticks Collected from Horses in the Republic of Korea.
Pathogens (Basel, Switzerland)    August 24, 2021   Volume 10, Issue 9 1069 doi: 10.3390/pathogens10091069
Seo HJ, Truong AT, Kim KH, Lim JY, Min S, Kim HC, Yoo MS, Yoon SS, Klein TA, Cho YS.The horse industry has grown rapidly as a leisure industry in the Republic of Korea (ROK) in parallel with an increased demand for equestrian activities. As a result, there has been an increase in horse breeding and equestrian population and potential exposure to ticks and their associated pathogens. To provide a better understanding of the potential disease risks of veterinary and medical importance, a study was conducted to determine the geographical distribution and diversity of ticks collected from horses and vegetation associated with horse racetracks/ranches throughout the ROK. This incl...
Home Sweet Home: New Insights Into the Location of Equine Premises in France and Keeping Habits to Inform Health Prevention and Disease Surveillance.
Frontiers in veterinary science    August 23, 2021   Volume 8 701749 doi: 10.3389/fvets.2021.701749
Farchati H, Merlin A, Saussac M, Dornier X, Dhollande M, Garon D, Tapprest J, Sala C.Identifying and tracking equines are key activities in equine health prevention. France is one of the few European countries with an operational centralized database that records information on equines, owners, and keepers but not on the location and keeping conditions of equines. The objective of our study was to collect information on keeping habits of equines and the relative location of a wide range of equines, owners, and keepers and discuss their implication for surveillance and control of outbreak improvement. A national email survey was conducted among the 1.9% of people registered as ...
Equine Embryo Mobility. A Friend of Theriogenologists.
Journal of equine veterinary science    August 21, 2021   Volume 106 103747 doi: 10.1016/j.jevs.2021.103747
Ginther OJ.Equine embryo mobility and cessation of mobility (fixation) provide explanations to several enigmas in reproductive biology of the pregnant mare and provide an efficient solution to the twinning problem, the bane of brood-mare owners. Embryo mobility is maximum on Days 12 to 15 (Day 0 = ovulation) while the spherical embryo is growing from 9 to 23 mm in diameter. During mobility, the embryo can be anywhere in the uterine lumen regardless of side of ovulation. Mobility solved the enigmas of how a small embryo can block luteolysis in a relatively massive uterus and why the side of ovulation do...
Equine Coital Exanthema: New Insights on the Knowledge and Leading Perspectives for Treatment and Prevention.
Pathogens (Basel, Switzerland)    August 20, 2021   Volume 10, Issue 8 1055 doi: 10.3390/pathogens10081055
Vissani MA, Damiani AM, Barrandeguy ME.Equine coital exanthema (ECE) is a highly contagious, venereally-transmitted mucocutaneous disease, characterized by the formation of papules, vesicles, pustules and ulcers on the external genital organs of mares and stallions, and caused by (EHV-3). The infection is endemic worldwide and the virus is transmitted mainly through direct contact during sexual intercourse and by contaminated instruments during reproductive maneuvers in breeding facilities. The disease does not result in systemic illness, infertility or abortion, yet it does have a negative impact on the equine industry as it forc...
Real-time fluorometric and end-point colorimetric isothermal assays for detection of equine pathogens C. psittaci and equine herpes virus 1: validation, comparison and application at the point of care.
BMC veterinary research    August 19, 2021   Volume 17, Issue 1 279 doi: 10.1186/s12917-021-02986-8
Jelocnik M, Nyari S, Anstey S, Playford N, Fraser TA, Mitchell K, Blishen A, Pollak NM, Carrick J, Chicken C, Jenkins C.C. psittaci has recently emerged as an equine abortigenic pathogen causing significant losses to the Australian Thoroughbred industry, while Equine herpesvirus-1 (EHV-1) is a well-recognized abortigenic agent. Diagnosis of these agents is based on molecular assays in diagnostic laboratories. In this study, we validated C. psittaci and newly developed EHV-1 Loop Mediated Isothermal Amplification (LAMP) assays performed in a real-time fluorometer (rtLAMP) against the reference diagnostic assays. We also evaluated isothermal amplification using commercially available colorimetric mix (cLAMP), and...
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