Analyze Diet

Topic:Disease Management

Disease management in horses encompasses the strategies and practices employed to prevent, control, and treat diseases affecting equine populations. This field involves understanding the etiology, transmission, and clinical presentation of various equine diseases, as well as implementing biosecurity measures and therapeutic interventions. Common diseases in horses include equine influenza, strangles, and equine herpesvirus. Effective disease management relies on accurate diagnosis, vaccination protocols, and the use of antimicrobials and other treatments. This page compiles peer-reviewed research studies and scholarly articles that explore the methodologies, challenges, and advancements in managing diseases in equine health.
Antiviral Medicinal Plants of Veterinary Importance: A Literature Review.
Planta medica    August 10, 2020   Volume 86, Issue 15 1058-1072 doi: 10.1055/a-1224-6115
Zitterl-Eglseer K, Marschik T.Viruses have a high mutation rate, and, thus, there is a continual emergence of new antiviral-resistant strains. Therefore, it becomes imperative to explore and develop new antiviral compounds continually. The search for pharmacological substances of plant origin that are effective against animal viruses, which have a high mortality rate or cause large economic losses, has garnered interest in the last few decades. This systematic review compiles 130 plant species that exhibit antiviral activity on 37 different virus species causing serious diseases in animals. The kind of extract, fraction, o...
Clinical insights: Equine obesity.
Equine veterinary journal    August 5, 2020   Volume 52, Issue 5 635-638 doi: 10.1111/evj.13307
Knowles EJ, Grieve L.No abstract available
Clinical insights: Musculoskeletal injury in the racehorse: What is new?
Equine veterinary journal    August 5, 2020   Volume 52, Issue 5 639-642 doi: 10.1111/evj.13309
Plevin S, McLellan J.No abstract available
Descriptive network analysis of a Standardbred horse training facility contact network: Implications for disease transmission.
The Canadian veterinary journal = La revue veterinaire canadienne    August 4, 2020   Volume 61, Issue 8 853-859 
Rossi TM, Milwid RM, Moore A, O'Sullivan TL, Greer AL.Infectious respiratory disease is a common cause of morbidity among racehorses. Quantification of contact patterns in training facilities could help inform disease prevention strategies. The study objectives were to: i) describe the contact network among horses, locations, and humans at a Standardbred horse training facility in Ontario; ii) describe the characteristics of highly influential individuals; and iii) investigate how management changes alter the network metrics and discuss the potential implications for disease transmission. Proximity loggers detected contacts among horses, staff, a...
Equine piroplasmosis: an insight into global exposure of equids from 1990 to 2019 by systematic review and meta-analysis.
Parasitology    August 3, 2020   Volume 147, Issue 13 1411-1424 doi: 10.1017/S0031182020001407
Onyiche TE, Taioe MO, Molefe NI, Biu AA, Luka J, Omeh IJ, Yokoyama N, Thekisoe O.Equine piroplasmosis (EP) is a tick-borne disease of economic importance, relevant in the international movement of equids. The causative agents are at least two apicomplexan protozoan parasites Babesia caballi and Theileria equi. To date, there is no study that estimates global and regional exposure of equids to EP. We therefore conducted a systematic review and meta-analysis to estimate the pooled prevalence and heterogeneity of EP using random-effects model. Six electronic databases were searched for publications on EP and assessed according to Preferred Reporting Items for Systematic Revie...
A first clinical case report of west nile viral encephalitis in poltava region of Ukraine.
Wiadomosci lekarskie (Warsaw, Poland : 1960)    August 1, 2020   Volume 73, Issue 4 831-834 
Kotelevska TM, Pryimenko NO, Dubynska HM, Iziumska OM, Koval TI, Pikul KV, Purdenko TY.West Nile Fever (WNF) is the most common arbovirus infection caused by West Nile Virus (WNV), which has been responsible for numerous epidemic outbreaks of disease among humans, birds and horses on all continents, with the exception of Antarctica, over the past two decades. On the territory of Ukraine, the earliest reports of cases of WNV circulation in humans and birds relate to the 70s of the XX century. In Poltava region WNF was first registered in 2011. Though the epidemiological and clinical patterns of WNF in Ukraine and Poltava region remain understudied, primarily due to the lack of al...
Bovine and equine trypanosomosis in Northwest Ethiopia: Prevalence, density of vectors and control measures.
Parasite epidemiology and control    July 31, 2020   Volume 11 e00170 doi: 10.1016/j.parepi.2020.e00170
Dagnachew S, Mohammed S, Dessie B, Tilahun M, Ayele A, Kefyalew H.A cross-sectional study was carried out from November 2016 to May 2017 in selected districts of Northwest Ethiopia (Jawi, South Achefer, Dembecha and Jabitehenan) with the aim of determining the prevalence of bovine and equine trypanosomosis, estimating the apparent density of vectors and assessing the effectiveness of control measures of the disease. A total of 1257 animals of which 803 bovine and 454 equine were examined for the determination of prevalence using blood sample collected from ear vein of animals. The buffy coat technique was employed to determine the prevalence and the packed c...
Molecular detection of 7SL-derived small RNA is a promising alternative for trypanosomosis diagnosis.
Transboundary and emerging diseases    July 31, 2020   Volume 67, Issue 6 3061-3068 doi: 10.1111/tbed.13744
Verney M, Grey F, Lemans C, Géraud T, Berthier D, Thévenon S, Rincé A, Hans A, Morrison L, Hébert L.Equine trypanosomosis comprises different parasitic diseases caused by protozoa of the subgenus Trypanozoon: Trypanosoma equiperdum (causative agent of dourine), Trypanosoma brucei (nagana) and Trypanosoma evansi (surra). Due to the absence of a vaccine and the lack of efficacy of the few available drugs, these diseases represent a major health and economic problem for international equine trade. Development of affordable, sensitive and specific diagnostic tests is therefore crucial to ensure the control of these diseases. Recently, it has been shown that a small RNA derived from the 7SL gene ...
Equine Asthma: Current Understanding and Future Directions.
Frontiers in veterinary science    July 30, 2020   Volume 7 450 doi: 10.3389/fvets.2020.00450
Couetil L, Cardwell JM, Leguillette R, Mazan M, Richard E, Bienzle D, Bullone M, Gerber V, Ivester K, Lavoie JP, Martin J, Moran G, Niedźwiedź A....The 2019 Havemeyer Workshop brought together researchers and clinicians to discuss the latest information on Equine Asthma and provide future research directions. Current clinical and molecular asthma phenotypes and endotypes in humans were discussed and compared to asthma phenotypes in horses. The role of infectious and non-infectious causes of equine asthma, genetic factors and proposed disease pathophysiology were reviewed. Diagnostic limitations were evident by the limited number of tests and biomarkers available to field practitioners. The participants emphasized the need for more accessi...
Author Correction: Detection of Neorickettsia risticii, the agent of Potomac horse fever, in horses from Rio de Janeiro, Brazil.
Scientific reports    July 29, 2020   Volume 10, Issue 1 13001 doi: 10.1038/s41598-020-69584-w
Paulino PG, Almosny N, Oliveira R, Viscardi V, Müller A, Guimarães A, Baldani C, da Silva C, Peckle M, Massard C, Santos H.An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners.
The Veterinary record    July 27, 2020   Volume 187, Issue 10 404 doi: 10.1136/vr.105880
Bowden A, Boynova P, Brennan ML, England GCW, Mair TS, Furness WA, Freeman SL, Burford JH.The study aim was to describe conditions seen 'out-of-hours' in equine practice. This was a retrospective case series of first opinion 'out-of-hours' cases seen at two equine practices between 2011 and 2013. Data were retrieved on case presentation, diagnostic testing, treatment administered and outcome, and diseases categorised using a systems-based coding system. A hierarchical logistic regression, formulated using a generalised linear model, was used to identify clinical variables associated with a binary outcome of 'critical' cases (required hospitalisation or euthanasia or died). Data fro...
Molecular detection of Coxiella burnetii in horse sera in Iran.
Comparative immunology, microbiology and infectious diseases    July 23, 2020   Volume 72 101521 doi: 10.1016/j.cimid.2020.101521
Khademi P, Ownagh A, Ataei B, Kazemnia A, Eydi J, Khalili M, M M, Mardani K.Coxiella burnetii is a zoonotic bacterium that can infect a wide range of animals including horses. However, its circulation dynamics in and through horses are still unclear. The aim of this study was to evaluate prevalence of C. burnetii and its genomic characteristics in horse sera samples in the North of Iran (Golestan Province). The samples were collected in 2018 and the age, sex, and breed of each animal were recorded. Nested-PCR was used to detect C. burnetii based on the presence of the transposable gene IS1111. The results showed that 7.50 % (P < 0.05; 95 % CI: 0.5 %-0.12 %) of the ...
Novel Equine Faecal Egg Diagnostics: Validation of the FECPAKG2.
Animals : an open access journal from MDPI    July 23, 2020   Volume 10, Issue 8 1254 doi: 10.3390/ani10081254
Tyson F, Dalesman S, Brophy PM, Morphew RM.Faecal egg counts (FECs) are the standard method of diagnosing the level of parasitic helminth egg shedding in horses and other grazing animals. Testing before treatment is an important factor in slowing the appearance of anthelmintic resistance in nematode parasites. The FECPAK, optimised for livestock, is reported to allow owners to perform FECs on their own animals without the need for a separate microscope or any specialist knowledge by tapping into remote expertise. However, the performance of the FECPAK has yet to be assessed for equids. Therefore, a comparison of the FECPAK (G2) method ...
West Nile Virus: An Update on Pathobiology, Epidemiology, Diagnostics, Control and “One Health” Implications.
Pathogens (Basel, Switzerland)    July 19, 2020   Volume 9, Issue 7 589 doi: 10.3390/pathogens9070589
Habarugira G, Suen WW, Hobson-Peters J, Hall RA, Bielefeldt-Ohmann H.West Nile virus (WNV) is an important zoonotic flavivirus responsible for mild fever to severe, lethal neuroinvasive disease in humans, horses, birds, and other wildlife species. Since its discovery, WNV has caused multiple human and animal disease outbreaks in all continents, except Antarctica. Infections are associated with economic losses, mainly due to the cost of treatment of infected patients, control programmes, and loss of animals and animal products. The pathogenesis of WNV has been extensively investigated in natural hosts as well as in several animal models, including rodents, lagom...
BEVA primary care clinical guidelines: Wound management in the horse.
Equine veterinary journal    July 17, 2020   Volume 53, Issue 1 18-29 doi: 10.1111/evj.13289
Freeman SL, Ashton NM, Elce YA, Hammond A, Hollis AR, Quinn G.There are currently no evidence summaries on wounds in the horse. Objective: To develop evidence-based guidelines on wound management in the horse. Methods: Evidence review using the GRADE framework. Methods: Research questions were proposed by a panel of veterinarians, and developed into PICO format. Evidence in the veterinary literature was evaluated using the GRADE evidence-to-decision framework. Searches for human evidence summaries were conducted in the NICE, Cochrane and JBI databases. Final recommendations were based on both veterinary and human evidence. Conclusions: The research quest...
Genetics of Equine Ocular Disease.
The Veterinary clinics of North America. Equine practice    July 14, 2020   Volume 36, Issue 2 303-322 doi: 10.1016/j.cveq.2020.03.009
Bellone RR.Horses perform in a variety of disciplines that are visually demanding, and any disease impacting the eye has the potential to threaten vision and thus the utility of the horse. Advances in equine genetics have enabled the understanding of some inherited ocular disorders and ocular manifestations and are enabling cross-species comparisons. Genetic testing for multiple congenital ocular anomalies, congenital stationary night blindness, equine recurrent uveitis, and squamous cell carcinoma can identify horses with or at risk for disease and thus can assist in clinical management and breeding dec...
Genetics, Genomics, and Emergent Precision Medicine 12 Years After the Equine Reference Genome Was Published.
The Veterinary clinics of North America. Equine practice    July 14, 2020   Volume 36, Issue 2 173-181 doi: 10.1016/j.cveq.2020.04.002
MacLeod JN, Kalbfleisch TS.The first equine reference genome was completed in 2007 and published in 2009. This major accomplishment has enabled equine science to advance in ways that broadly parallel the transformative impact that genomics has had on many animal species including humans. A conceptual overview of reference genomes, genome annotation, and the major implications for equine science is presented. The relationship between genomic sequencing and the accelerating application of precision P4 medicine is discussed in the context of human and equine patients. Emergent technologies built on the foundation of genomi...
Infection dynamics of Theileria equi in carrier horses is associated with management and tick exposure.
Ticks and tick-borne diseases    July 11, 2020   Volume 11, Issue 6 101508 doi: 10.1016/j.ttbdis.2020.101508
Tirosh-Levy S, Gottlieb Y, Mazuz ML, Savitsky I, Steinman A.The tick-borne equine hemoparasite, Theileria equi, is endemic in many parts of the world where prevalence may be high, and most infected horses are apparently healthy but serve as life-long carriers. To determine the factors that affect T. equi dynamics, we followed parasitic loads in apparently healthy horses at four time points during one year. A total of 1094 blood samples were collected from 395 horses, along with ticks and demographic and clinical data. Infection and load of T. equi were tested by PCR and qPCR, and for the spring dataset, infection was also tested serologically by IFAT (...
Antimicrobial Resistance in Horses.
Animals : an open access journal from MDPI    July 9, 2020   Volume 10, Issue 7 doi: 10.3390/ani10071161
Steinman A, Navon-Venezia S.Antimicrobial resistance (AMR) is an increasingly recognized global public health threat to the modern health-care system that could hamper the control and treatment of infectious diseases [...].
Draft genome sequence of the oomycete Pythium destruens strain ATCC 64221 from a horse with pythiosis in Australia.
BMC research notes    July 9, 2020   Volume 13, Issue 1 329 doi: 10.1186/s13104-020-05168-1
Krajaejun T, Kittichotirat W, Patumcharoenpol P, Rujirawat T, Lohnoo T, Yingyong W.Genome sequences are a vital resource for accelerating the biological exploration of an organism of interest. Pythium destruens (a synonym of Pythium insidiosum) causes a difficult-to-treat infectious disease called pythiosis worldwide. Detection and management of pythiosis are challenging. Basic knowledge of the disease is lacking. Genomes of this organism isolated from different continents (i.e., Asia and the Americas) have been sequenced and publicly available. Here, we sequenced the genome of an Australian isolate of P. destruens. Genome data will facilitate the comparative analysis of thi...
Antimicrobial Resistance in Horses.
Animals : an open access journal from MDPI    July 9, 2020   Volume 10, Issue 7 doi: 10.3390/ani10071161
Steinman A, Navon-Venezia S.Antimicrobial resistance (AMR) is an increasingly recognized global public health threat to the modern health-care system that could hamper the control and treatment of infectious diseases [...].
Prevalence of endo- and ecto-parasites of equines in Iran: A systematic review.
Veterinary medicine and science    July 9, 2020   Volume 7, Issue 1 25-34 doi: 10.1002/vms3.321
Khamesipour F, Taktaz-Hafshejani T, Tebit KE, Razavi SM, Hosseini SR.Equines are subject to infection with many parasites, which threaten their health. In the present study, we systematically reviewed existing literature on the prevalence of endo- and ectoparasites of equines in Iran. Major electronic databases, including PubMed, PubMed Central, Google Scholar, Science Direct and Scientific Information Database (SID), were searched (Last updated 11/05/2018) for relevant literature of parasites that have been identified from equines in Iran. Of the 1809 titles produced by bibliographic search, 38 were included in the review. Twenty-seven of the studies were on h...
Respiratory metabolites in bronchoalveolar lavage fluid (BALF) and exhaled breath condensate (EBC) can differentiate horses affected by severe equine asthma from healthy horses.
BMC veterinary research    July 8, 2020   Volume 16, Issue 1 233 doi: 10.1186/s12917-020-02446-9
Bazzano M, Laghi L, Zhu C, Magi GE, Tesei B, Laus F.The use of an untargeted metabolomic approach to investigate biofluids of respiratory origin is of increasing interest in human and veterinary lung research. Considering the high incidence of equine asthma (> 14%) within horse population and the importance of this animal model for human disease, we aimed to investigate the metabolomic profile of bronchoalveolar lavage fluid (BALF) and exhaled breath condensate (EBC) in healthy and asthmatic horses. Results: On the basis of clinical, endoscopic and BALF cytology findings, 6 horses with severe asthma (Group A) and 6 healthy horses (Group C) we...
Conditions predict heightened Hendra virus spillover risk in horses this winter: actions now can change outcomes.
Australian veterinary journal    July 1, 2020   Volume 98, Issue 6 270-271 doi: 10.1111/avj.12964
Eby P, Plowright RK, McCallum H, Peel AJ.No abstract available
Evaluating 5.5 Years of Equinella: A Veterinary-Based Voluntary Infectious Disease Surveillance System of Equines in Switzerland.
Frontiers in veterinary science    June 30, 2020   Volume 7 327 doi: 10.3389/fvets.2020.00327
Özçelik R, Graubner C, Remy-Wohlfender F, Dürr S, Faverjon C.Equine health is important in regard to trade, economy, society, and the veterinary, as well as public health. To reduce the burden of equine infectious diseases internationally, it is important to collect, review, and distribute equine health surveillance data as accurate and timely as possible. Within this study, we aimed at providing a comprehensive descriptive analysis of data submitted to Equinella, a voluntary veterinary-based surveillance system of non-notifiable equine infectious diseases and clinical signs, in Switzerland. This was achieved by reviewing the reports submitted since its...
Detection of atrial fibrillation with implantable loop recorders in horses.
Equine veterinary journal    June 28, 2020   Volume 53, Issue 2 397-403 doi: 10.1111/evj.13301
Buhl R, Hesselkilde EM, Carstensen H, Fenner MF, Jespersen T, Tfelt-Hansen J, Michael Sattler S.Cardiac arrhythmias in horses are diagnosed by auscultation or electrocardiogram (ECG), which results in a low sensitivity for detecting arrhythmias that occur sporadically. Implantable loop recorders (ILRs) are small ECG devices placed subcutaneously, to automatically detect arrhythmias in human patients. Objective: To test ILRs ability to detect atrial fibrillation (AF) in horses. Furthermore, we hypothesised that anatomical location of the implant site might influence signal quality. Signal quality was evaluated both during exercise and over time. Methods: Experimental study. Methods: In fi...
Science-in-brief: Equine coronavirus – a decade long journey to investigate an emerging enteric virus of adult horses.
Equine veterinary journal    June 26, 2020   Volume 52, Issue 5 651-653 doi: 10.1111/evj.13288
Pusterla N.No abstract available
Nationwide serological surveillance of non-tsetse-transmitted horse trypanosomoses in Mongolia.
Parasite epidemiology and control    June 25, 2020   Volume 10 e00158 doi: 10.1016/j.parepi.2020.e00158
Mizushima D, Amgalanbaatar T, Davaasuren B, Kayano M, Naransatsral S, Myagmarsuren P, Otgonsuren D, Enkhtaivan B, Davkharbayar B, Mungun-Ochir B....In Mongolia, horses play important roles, not only in livestock production, but also in terms of culture, tradition, and Mongolian beliefs. Although the presence of non-tsetse-transmitted horse trypanosomoses, which are caused by infections with (surra) and (dourine), has been reported in the country, whether there is a nationwide epidemic of these infectious diseases is unknown. In the present study, a nationwide surveillance of horse trypanosomoses was performed. The sample sizes for each province, the whole country, and male and female horses were, respectively, 96, 2,400, and 316 and 306...
Extension Horses, Inc. experts act fast to create online resources to assist the horse industry during COVID-19.
Translational animal science    June 25, 2020   Volume 4, Issue 3 txaa085 doi: 10.1093/tas/txaa085
Greene EA, Hein W, Wickens CL, Smarsh DN.The COVID-19 pandemic and resulting stay-at-home directives, adopted out of necessity to protect human health, introduced significant challenges for horse owners and small equine businesses. Restricted access, and in many cases closure of barns, resulted in a multitude of questions and concerns within the equine community which needed to be addressed rapidly. Extension Horses, Inc. (EH) coordinated the development and delivery of a variety of educational resources utilizing a combination of online formats and dissemination through social media and EH member contact lists. A series of infograph...
Applications of minimally invasive multimodal telemetry for continuous monitoring of brain function and intracranial pressure in macaques with acute viral encephalitis.
PloS one    June 25, 2020   Volume 15, Issue 6 e0232381 doi: 10.1371/journal.pone.0232381
Ma H, Lundy JD, Cottle EL, O'Malley KJ, Trichel AM, Klimstra WB, Hartman AL, Reed DS, Teichert T.Alphaviruses such as Venezuelan equine encephalitis virus (VEEV) and Eastern equine encephalitis virus (EEEV) are arboviruses that can cause severe zoonotic disease in humans. Both VEEV and EEEV are highly infectious when aerosolized and can be used as biological weapons. Vaccines and therapeutics are urgently needed, but efficacy determination requires animal models. The cynomolgus macaque (Macaca fascicularis) provides a relevant model of human disease, but questions remain whether vaccines or therapeutics can mitigate CNS infection or disease in this model. The documentation of alphavirus e...
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