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Topic:Disease Prevention

Disease prevention in horses encompasses strategies and practices aimed at minimizing the occurrence and spread of infectious and non-infectious diseases within equine populations. These practices include vaccination programs, biosecurity measures, and regular health monitoring. Vaccination helps to stimulate the horse's immune system to protect against specific pathogens, while biosecurity measures, such as quarantine and sanitation, reduce the risk of disease transmission. Regular health monitoring, including physical examinations and diagnostic testing, aids in early detection and management of potential health issues. This page compiles peer-reviewed research studies and scholarly articles that explore various methods and their effectiveness in preventing diseases in horses, as well as the development and implementation of prevention programs in different equine settings.
Does periosteal scraping of the third metacarpal bone reduce the incidence of ‘bucked shins’ in young Thoroughbred racehorses?
Equine veterinary journal    December 23, 2013   Volume 46, Issue 5 560-566 doi: 10.1111/evj.12197
Plevin S, McLellan J.The occurrence of bucked shins in young Thoroughbred racehorses in North America is high. Although an altered training regime has demonstrated a significant decrease in this condition, trainers can be opposed to altering something as fundamental as their training routine. Periosteal scraping of the third metacarpal bone (McIII) is a putative prophylactic technique used to prevent bucked shins; therefore, a study to investigate the validity of the procedure is warranted. Objective: To investigate whether prophylactic McIII scraping: 1) reduces the incidence of bucked shins in juvenile Thoroughb...
The future of helminth control in horses.
Equine veterinary journal    December 18, 2013   Volume 46, Issue 1 10-11 doi: 10.1111/evj.12200
Matthews JB.No abstract available
EVE and EVJ online collection of equine endocrinology: recent and future directions; a great start, but still a long way to go.
Equine veterinary journal    December 18, 2013   Volume 46, Issue 1 97-98 doi: 10.1111/evj.12217
Marr CM, Mair TS.No abstract available
Hard Tick Species of Livestock and their Bioecology in Golestan Province, North of Iran.
Journal of arthropod-borne diseases    December 18, 2013   Volume 8, Issue 1 108-116 
Sofizadeh A, Telmadarraiy Z, Rahnama A, Gorganli-Davaji A, Hosseini-Chegeni A.A survey on tick species composition was carried out in Golestan Province Iran during year 2010-2011.The aim was to determine tick species parasitizing domestic ruminants and their seasonal population dynamics. Methods: A total of 124 sheep, 92 goats, 84 cattle, 74 camels and 12 horses in several villages were inspected for tick infestation. The collected ticks preserved in 70% alcohol and then were identified. Results: The overall 1059 ticks (453 female, 606 male) were collected. The ticks occur on sheep, goats, cattle, camels and horses as 72.1%, 77.3%, 75.8%, 69.3%, and 50% respectively. Th...
Assessment of the safety and immunogenicity of Rhodococcus equi-secreted proteins combined with either a liquid nanoparticle (IMS 3012) or a polymeric (PET GEL A) water-based adjuvant in adult horses and foals–identification of promising new candidate antigens.
Veterinary immunology and immunopathology    December 17, 2013   Volume 157, Issue 3-4 164-174 doi: 10.1016/j.vetimm.2013.12.003
Cauchard S, Bertrand F, Barrier-Battut I, Jacquet S, Laurentie M, Barbey C, Laugier C, Deville S, Cauchard J.Rhodococcus equi is the most common infectious cause of mortality in foals between 1 and 6 months of age. Because of an increase in the number of antibiotic-resistant strains, the optimization of a prophylactic strategy is a key factor in the comprehensive management of R. equi pneumonia. The objectives of this study were to assess the safety and immunogenicity of R. equi-secreted proteins (ReSP) co-administered with either the nanoparticular adjuvant Montanide™ IMS 3012 VG, or a new polymeric adjuvant Montanide™ PET GEL A, and to further investigate the most immunogenic proteins for subse...
Response to Stancampiano et al. (2013), Letter to the Editor.
Veterinary parasitology    December 14, 2013   Volume 200, Issue 1-2 229-230 doi: 10.1016/j.vetpar.2013.12.006
Lichtenfels JR, Kharchenko VA.No abstract available
In vitro reproduction of the life cycle of Pythium insidiosum from kunkers’ equine and their role in the epidemiology of pythiosis.
Mycopathologia    December 11, 2013   Volume 177, Issue 1-2 123-127 doi: 10.1007/s11046-013-9720-6
Fonseca AO, Botton Sde A, Nogueira CE, Corrêa BF, Silveira Jde S, de Azevedo MI, Maroneze BP, Santurio JM, Pereira DI.Pythium insidiosum is an important pathogen of mammals' species, including humans. Equine is the main species affected by this oomycete. P. insidiosum requires an aquatic environment to develop its life cycle, and the susceptible hosts are contaminated when they contact the microorganism in swampy areas. The equine pythiosis is characterized by the formation of irregular masses within the cutaneous lesions, called kunkers, which easily detach from the lesion. From these structures, it is possible to isolate P. insidiosum in pure cultures. The present study aimed to reproduce in vitro the life ...
Faecal worm egg count analysis for targeting anthelmintic treatment in horses: points to consider.
Equine veterinary journal    December 10, 2013   Volume 46, Issue 2 139-145 doi: 10.1111/evj.12199
Lester HE, Matthews JB.Equine gastrointestinal nematodes are ubiquitous; in horses that graze contaminated pasture and that are not treated appropriately, large numbers of worms can accumulate, which can lead to serious clinical disease. Nematode control has traditionally followed interval treatment regimens, which involve regular anthelmintic administration to all horses based on the strongyle egg reappearance periods of each drug, usually defined around the time of licensing. Interval treatment programmes have resulted in substantial reductions in large strongyle disease, but have made major contributions to the d...
Comparison of two sampling and culture systems for detection of Salmonella enterica in the environment of a large animal hospital.
Equine veterinary journal    December 5, 2013   Volume 46, Issue 4 499-502 doi: 10.1111/evj.12193
Ruple-Czerniak A, Bolte DS, Burgess BA, Morley PS.Nosocomial salmonellosis is an important problem in veterinary hospitals that treat horses and other large animals. Detection and mitigation of outbreaks and prevention of healthcare-associated infections often require detection of Salmonella enterica in the hospital environment. Objective: To compare 2 previously published methods for detecting environmental contamination with S. enterica in a large animal veterinary teaching hospital. Methods: Hospital-based comparison of environmental sampling techniques. Methods: A total of 100 pairs of environmental samples were collected from stalls us...
Prophylactic digital cryotherapy is associated with decreased incidence of laminitis in horses diagnosed with colitis.
Equine veterinary journal    December 5, 2013   Volume 46, Issue 5 554-559 doi: 10.1111/evj.12156
Kullmann A, Holcombe SJ, Hurcombe SD, Roessner HA, Hauptman JG, Geor RJ, Belknap J.Recent research suggested that prophylactic digital cryotherapy (ICE) improved lameness scores, diminished histological changes and early laminar inflammatory signalling in horses following oligofructose administration. In clinical practice, horses at risk for sepsis-associated laminitis receive ICE. Evidence to support this practice is lacking. Objective: To determine factors associated with development of laminitis in horses diagnosed with colitis, including ICE. Methods: Multicentre retrospective case series. Methods: Medical records for horses admitted to 2 university hospitals diagnosed w...
Expression of cyclo-oxygenases-1 and -2, and microsomal prostaglandin E synthase-1 in penile and preputial papillomas and squamous cell carcinomas in the horse.
Equine veterinary journal    December 5, 2013   Volume 46, Issue 5 618-624 doi: 10.1111/evj.12144
van den Top JG, Harkema L, Ensink JM, Barneveld A, Martens A, van de Lest CH, van Weeren PR, Gröne A.Penile and preputial papilloma and squamous cell carcinoma (SCC) are commonly diagnosed in horses. Papillomas have the potential to progress to potentially lethal SCC. Knowledge of pathogenetic mechanisms may help in prevention and definition of treatment targets. Methods: Retrospective study using archived material. Objective: To determine the expression of cyclo-oxygenase 1 (COX-1), cyclo-oxygenase 2 (COX-2) and microsomal prostaglandin E synthase-1 (mPGES-1) in penile and preputial normal tissue, papilloma and SCC in horses, and whether expression of these enzymes is influenced by degree of...
Novel vaccination approaches against equine alphavirus encephalitides.
Vaccine    December 2, 2013   Volume 32, Issue 3 311-319 doi: 10.1016/j.vaccine.2013.11.071
Carossino M, Thiry E, de la Grandière A, Barrandeguy ME.The current production of inactivated vaccines for the prevention of equine alphavirus encephalitides caused by Eastern, Western and Venezuelan Equine Encephalitis viruses (EEEV, WEEV, VEEV) involves the manipulation of large quantities of infectious viral particles under biosafety level 3 containment laboratories with the potential risk of transmission to the operators. Moreover, these vaccines are not capable of inducing a long-lasting immunity. Modified live vaccines, which were also attempted, maintain residual virulence and neurotropism, causing disease in both horses and humans. Therefor...
Recrudescent infection supports Hendra virus persistence in Australian flying-fox populations.
PloS one    November 28, 2013   Volume 8, Issue 11 e80430 doi: 10.1371/journal.pone.0080430
Wang HH, Kung NY, Grant WE, Scanlan JC, Field HE.Zoonoses from wildlife threaten global public health. Hendra virus is one of several zoonotic viral diseases that have recently emerged from Pteropus species fruit-bats (flying-foxes). Most hypotheses regarding persistence of Hendra virus within flying-fox populations emphasize horizontal transmission within local populations (colonies) via urine and other secretions, and transmission among colonies via migration. As an alternative hypothesis, we explore the role of recrudescence in persistence of Hendra virus in flying-fox populations via computer simulation using a model that integrates publ...
Standing laparoscopic inguinal hernioplasty using cyanoacrylate for preventing recurrence of acquired strangulated inguinal herniation in 10 stallions.
Veterinary surgery : VS    November 27, 2013   Volume 43, Issue 1 6-11 doi: 10.1111/j.1532-950X.2013.12083.x
Rossignol F, Mespoulhes-Rivière C, Vitte A, Lechartier A, Boening KJ.To describe a technique for standing inguinal hernioplasty in horses using cyanoacrylate glue, and to evaluate its effect on prevention of recurrent inguinal herniation in stallions that had previous acquired strangulated inguinal hernia (SIH). Methods: Case series. Methods: Stallions (n = 10) with a history of SIH. Methods: Hernioplasty was performed in standing horses using 4 laparoscopic portals. The mesorchium was retracted caudomedially using Babcock forceps. A flexible polyethylene extension tube was introduced through the sheath of a laparoscopic needle and n-butyl-2-cyanoacrylate (2 mL...
Nature helps: food addition of micronized coconut and onion reduced worm load in horses and sheep and increased body weight in sheep.
Parasitology research    November 24, 2013   Volume 113, Issue 1 305-310 doi: 10.1007/s00436-013-3706-7
Jatzlau A, Abdel-Ghaffar F, Gliem G, Mehlhorn H.Intense laboratory tests on experimentally infected mice and rats had shown that a mixture of micronized onions and coconut pulp decreases substantially (until disappearance) the worm load (trematodes, cestodes and nematodes) after oral uptake. As a consequence, feeding experiments of naturally infected sheep had been done in Egypt, in Saudi Arabia, and in Germany, which showed that treated animals grow up much better than untreated ones. The mean gain of body weight per animal was up to 6 kg within 4 weeks compared to untreated ones. These experiments were repeated again in the present study ...
Hendra virus and horse owners–risk perception and management.
PloS one    November 15, 2013   Volume 8, Issue 11 e80897 doi: 10.1371/journal.pone.0080897
Kung N, McLaughlin A, Taylor M, Moloney B, Wright T, Field H.Hendra virus is a highly pathogenic novel paramyxovirus causing sporadic fatal infection in horses and humans in Australia. Species of fruit-bats (genus Pteropus), commonly known as flying-foxes, are the natural host of the virus. We undertook a survey of horse owners in the states of Queensland and New South Wales, Australia to assess the level of adoption of recommended risk management strategies and to identify impediments to adoption. Survey questionnaires were completed by 1431 respondents from the target states, and from a spectrum of industry sectors. Hendra virus knowledge varied with ...
An ethicist’s commentary on horse with possible equine herpes virus.
The Canadian veterinary journal = La revue veterinaire canadienne    October 25, 2013   Volume 54, Issue 10 922 
Rollin BE.No abstract available
Effect of hay steaming on forage nutritive values and dry matter intake by horses.
Journal of animal science    October 21, 2013   Volume 91, Issue 12 5813-5820 doi: 10.2527/jas.2013-6333
Earing JE, Hathaway MR, Sheaffer CC, Hetchler BP, Jacobson LD, Paulson JC, Martinson KL.Management strategies for horses with respiratory disease include soaking hay before feeding. Hay steaming is an alternative to this practice; however, little is known about its impact on forage nutritive values or intake. The objective was to determine the effect of steaming on forage nutritive value and intake by horses. Two alfalfa (Medicago sativa L.)-orchardgrass (Dactylis glomerata L.) mixed hays were evaluated: a low moldy (NM) and moderately moldy (MM) hay. Six mature horses were used in a 10 d crossover design. Three horses were assigned to each hay type and treatments were switched o...
Equine melanocytic tumors.
The Veterinary clinics of North America. Equine practice    October 18, 2013   Volume 29, Issue 3 673-687 doi: 10.1016/j.cveq.2013.08.008
Phillips JC, Lembcke LM.Melanomas are among the most common skin tumors in horses, with prevalence rates reaching as high as 80% in adult gray horses. Most melanocytic tumors are benign at initial presentation; however, if left untreated, up to two-thirds can progress to overt malignant behavior. Standard local treatment options can be used to treat solitary early-stage lesions but do not address the underlying risk of recurrent tumor formation or the transformation to a malignant phenotype. An understanding of the specific molecular genetic factors associated with tumor formation should lead to targeted therapies th...
Equine hyperimmune serum protects mice against Clostridium difficile spore challenge.
Journal of veterinary science    October 18, 2013   Volume 15, Issue 2 249-258 doi: 10.4142/jvs.2014.15.2.249
Yan W, Shin KS, Wang SJ, Xiang H, Divers T, McDonough S, Bowman J, Rowlands A, Akey B, Mohamed H, Chang YF.Clostridium (C.) difficile is a common cause of nosocomial diarrhea in horses. Vancomycin and metronidazole have been used as standard treatments but are only moderately effective, which highlights the need for a novel alternative therapy. In the current study, we prepared antiserum of equine origin against both C. difficile toxins A and B as well as whole-cell bacteria. The toxin-neutralizing activities of the antibodies were evaluated in vitro and the prophylactic effects of in vivo passive immunotherapy were demonstrated using a conventional mouse model. The data demonstrated that immunized...
Influenza: are we protecting our horses effectively?
Equine veterinary journal    October 15, 2013   Volume 45, Issue 6 766-767 doi: 10.1111/evj.12172
Marr CM, Sellon D, Mountford D.No abstract available
Vaccination for equine influenza: the sports regulator’s viewpoint.
Equine veterinary journal    October 15, 2013   Volume 45, Issue 6 770-771 doi: 10.1111/evj.12151
Cooke G.No abstract available
Influenza vaccine strains: licensing perspectives.
Equine veterinary journal    October 15, 2013   Volume 45, Issue 6 772-773 doi: 10.1111/evj.12155
Woodland RM.No abstract available
Equine influenza: antigenic drift and implications for vaccines.
Equine veterinary journal    October 15, 2013   Volume 45, Issue 6 768-769 doi: 10.1111/evj.12148
Elton D, Cullinane A.No abstract available
Equine influenza vaccines in Europe: a view from the animal health industry.
Equine veterinary journal    October 15, 2013   Volume 45, Issue 6 774-775 doi: 10.1111/evj.12171
Horspool LJ, King A.No abstract available
Infectious folliculitis and dermatophytosis.
The Veterinary clinics of North America. Equine practice    October 10, 2013   Volume 29, Issue 3 559-575 doi: 10.1016/j.cveq.2013.09.004
Weese JS, Yu AA.Bacterial, dermatophilosis, and superficial ringworm infections are common skin diseases noted in equine dermatology. The ability to recognize and accurately diagnose the skin condition is key to selecting an appropriate and successful treatment regimen. Addressing underlying etiology, environmental management, and infection control play a crucial role in preventing relapse of clinical signs.
Failure of a VapA/CpG oligodeoxynucleotide vaccine to protect foals against experimental Rhocococcus equi pneumonia despite induction of VapA-specific antibody and interferon-γ response.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    October 9, 2013   Volume 77, Issue 3 161-169 
Lohmann KL, Lopez AM, Manning ST, Marques FJ, Brownlie R, Allen AL, Sangster AE, Mutwiri G, Gerdts V, Potter A, Townsend HG.We evaluated the immunogenic and protective potential of a recombinant VapA/CpG oligodeoxynucleotide (ODN) 2395 vaccine in neonatal foals undergoing experimental Rhodococcus equi challenge. Foals (n = 8) were vaccinated by intramuscular injection on days 1 and 15 of the study; control foals (n = 7) received a phosphate-buffered saline (PBS) solution. All foals were challenged by intrabronchial administration of 5 × 10⁶ R. equi 103⁺ on day 29. Bronchoalveolar lavages were done on days 15, 29, and 36 and total cell count, differential cell count, rVapA-stimulated cell proliferation and inte...
Helping working Equidae and their owners in developing countries: monitoring and evaluation of evidence-based interventions.
Veterinary journal (London, England : 1997)    October 4, 2013   Volume 199, Issue 2 210-216 doi: 10.1016/j.tvjl.2013.09.065
Upjohn MM, Pfeiffer DU, Verheyen KL.There are an estimated 112 million Equidae (horses, donkeys, mules) in the developing world, providing essential resources for their owners' livelihoods and well-being. The impoverished situation of their owners and the often harsh conditions in which they work mean that the animals' welfare is a cause for concern. A number of equine non-governmental organisations (NGOs) operate within working equid communities providing veterinary care, education and training programmes aimed at improving equine welfare. However, there is little published information available that describes monitoring and ev...
Mycotoxicoses of ruminants and horses. Riet-Correa F, Rivero R, Odriozola E, Adrien Mde L, Medeiros RM, Schild AL.In the current study, mycotoxicoses of ruminants and horses are reviewed, with an emphasis on the occurrence of these diseases in South America. The main mycotoxicoses observed in grazing cattle include intoxications by indole-diterpenoid mycotoxins (Paspalum spp. contaminated by Claviceps paspali, Lolium perenne infected by Neotyphodium lolii, Cynodon dactylon infected by Claviceps cynodontis, and Poa huecu), gangrenous ergotism and dysthermic syndrome (hyperthermia) caused by Festuca arundinacea (syn. Festuca elatior) infected by Neotyphodium coenophialum (syn. Acremonium coenophialum), and ...
A cost comparison of faecal egg count-directed anthelmintic delivery versus interval programme treatments in horses.
The Veterinary record    September 25, 2013   Volume 173, Issue 15 371 doi: 10.1136/vr.101804
Lester HE, Bartley DJ, Morgan ER, Hodgkinson JE, Stratford CH, Matthews JB.No abstract available
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