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Topic:Disease Transmission

Disease transmission in horses refers to the spread of infectious agents such as bacteria, viruses, fungi, and parasites among equine populations. These pathogens can be transmitted through various routes, including direct contact, vector-borne transmission, or environmental exposure. Factors influencing disease transmission include horse density, management practices, and biosecurity measures. Understanding the mechanisms and conditions that facilitate the spread of diseases is essential for developing effective prevention and control strategies. This page compiles peer-reviewed research studies and scholarly articles that investigate the modes of transmission, risk factors, and management practices related to infectious diseases in horses.
Avian influenza viruses in mammals.
Revue scientifique et technique (International Office of Epizootics)    July 22, 2009   Volume 28, Issue 1 137-159 doi: 10.20506/rst.28.1.1876
Reperant LA, Rimmelzwaan GF, Kuiken T.Highly pathogenic avian influenza viruses of subtype H5N1 are remarkable because of their expanding non-avian host range and wide tissue tropism. They have caused severe or fatal respiratory and extra-respiratory disease in seven naturally infected species of carnivore. However, they are not unique in their ability to cross the species barrier, to cause clinical disease and mortality, or to replicate in extra-respiratory organs. Low pathogenic avian influenza viruses have crossed from birds to swine, horses, harbour seals, whales and mink; have resulted in severe respiratory disease and mortal...
Case reports versus evidence-based medicine (EBM).
Equine veterinary journal    July 1, 2009   Volume 41, Issue 4 322-323 doi: 10.2746/042516409x429185
Rossdale PD.No abstract available
Changes in West Nile virus seroprevalence and antibody titers among Wisconsin mesopredators 2003-2006.
The American journal of tropical medicine and hygiene    June 27, 2009   Volume 81, Issue 1 177-179 
Docherty DE, Samuel MD, Egstad KF, Griffin KM, Nolden CA, Karwal L, Ip HS.After the 2001 occurrence of West Nile virus (WNV) in Wisconsin (WI), we collected sera, during 2003-2006, from south-central WI mesopredators. We tested these sera to determine WNV antibody prevalence and geometric mean antibody titer (GMAT). Four-fold higher antibody prevalence and 2-fold higher GMAT in 2003-2004 indicated greater exposure of mesopredators to WNV during the apparent epizootic phase. The period 2005-2006 was likely the enzootic phase because WNV antibody prevalence fell to a level similar to other flaviviruses. Our results suggest that, in mesopredators, vector-borne transmis...
Interspecies transmission of equine influenza virus (H3N8) to dogs by close contact with experimentally infected horses.
Veterinary microbiology    June 21, 2009   Volume 139, Issue 3-4 351-355 doi: 10.1016/j.vetmic.2009.06.015
Yamanaka T, Nemoto M, Tsujimura K, Kondo T, Matsumura T.In horse populations, influenza A virus subtype H3N8 (equine influenza virus, EIV) is a very important pathogen that leads to acute respiratory disease. Recently, EIV has emerged in dogs, and has become widespread among the canine population in the United States. The interspecies transmission route had thus far remained unclear. Here, we tested whether the interspecies transmission of EIV to dogs could occur as a result of close contact with experimentally EIV-infected horses. Three pairs consisting of an EIV-infected horse and a healthy dog were kept together in individual stalls for 15 conse...
[‘Emerging vector-borne diseases’ in the horse].
Tijdschrift voor diergeneeskunde    June 16, 2009   Volume 134, Issue 10 439-447 
Sloet van Oldruitenborgh-Oosterbaan MM, Goehring LS, Koopmans MP, van Rijn PA, van Maanen C.No abstract available
Identification and isolation of cDNA clones encoding the abundant secreted proteins in the saliva proteome of Culicoides nubeculosus.
Insect molecular biology    June 16, 2009   Volume 18, Issue 3 383-393 doi: 10.1111/j.1365-2583.2009.00882.x
Russell CL, Heesom KJ, Arthur CJ, Helps CR, Mellor PS, Day MJ, Torsteinsdottir S, Björnsdóttir TS, Wilson AD.Culicoides spp. are vectors of several infectious diseases of veterinary importance and a major cause of allergy in horses and other livestock. Their saliva contains a number of proteins which enable blood feeding, enhance disease transmission and act as allergens. We report the construction of a novel cDNA library from Culicoides nubeculosus linked to the analysis of abundant salivary gland proteins by mass spectrometry. Fifty-four novel proteins sequences are described including those of the enzymes maltase, hyaluronidase and two serine proteases demonstrated to be present in Culicoides sali...
Trypanosoma vivax displays a clonal population structure.
International journal for parasitology    June 8, 2009   Volume 39, Issue 13 1475-1483 doi: 10.1016/j.ijpara.2009.05.012
Duffy CW, Morrison LJ, Black A, Pinchbeck GL, Christley RM, Schoenefeld A, Tait A, Turner CM, MacLeod A.African animal trypanosomiasis, or Nagana, is a debilitating and economically costly disease with a major impact on animal health in sub-Saharan Africa. Trypanosoma vivax, one of the principal trypanosome species responsible for the disease, infects a wide host range including cattle, goats, horses and donkeys and is transmitted both cyclically by tsetse flies and mechanically by other biting flies, resulting in a distribution covering large swathes of South America and much of sub-Saharan Africa. While there is evidence for mating in some of the related trypanosome species, Trypanosoma brucei...
Host-feeding patterns of Aedes albopictus (Diptera: Culicidae) in urban and rural contexts within Rome province, Italy.
Vector borne and zoonotic diseases (Larchmont, N.Y.)    June 3, 2009   Volume 10, Issue 3 291-294 doi: 10.1089/vbz.2009.0007
Valerio L, Marini F, Bongiorno G, Facchinelli L, Pombi M, Caputo B, Maroli M, Della Torre A.Knowledge of the frequency of contact between a mosquito species and its different hosts is essential to understand the role of each vector species in the transmission of diseases to humans and/or animals. However, no data are so far available on the feeding habits of Aedes albopictus in Italy or in other recently colonized temperate regions of Europe, due to difficulties in collecting blood-fed females of this diurnal and exophilic species. We analyzed Ae. albopictus host-feeding patterns in two urban and two rural sites within the area of Rome (Italy). Ae. albopictus was collected using stic...
Risk of equine infectious anemia virus disease transmission through in vitro embryo production using somatic cell nuclear transfer.
Theriogenology    May 30, 2009   Volume 72, Issue 3 289-299 doi: 10.1016/j.theriogenology.2009.03.009
Gregg K, Polejaeva I.Prevention and regulation of equine infectious anemia virus (EIAV) disease transmission solely depend on identification, isolation, and elimination of infected animals because of lack of an effective vaccine. Embryo production via the somatic cell nuclear transfer (SCNT) technology uses oocytes collected mainly from untested animals, which creates a potential risk of EIAV transmission through infected embryos. The current review examines the risk of EIAV disease transmission through SCNT embryo production and transfer. Equine infectious anemia virus is a lentivirus from the family Retroviridae...
The role of land use patterns in limiting the spread of equine influenza in Queensland during the 2007 epidemic.
Transboundary and emerging diseases    May 22, 2009   Volume 56, Issue 8 292-302 doi: 10.1111/j.1865-1682.2009.01080.x
East IJ.In 2007, an epizootic of equine influenza (EI) occurred in Australia, involving parts of the states of Queensland and New South Wales. Following an extensive control program, the disease was eradicated within 4 months, after infecting more than 75,000 horses on over 10,000 properties. In Queensland, examination of land use patterns revealed that the majority of infected premises (89.5%) were located in one of three land use classes viz. rural residential, residential-unspecified or grazing natural vegetation. All nine clusters of infection in Queensland were surrounded to some degree by parcel...
Clinical impressions of anthrax from the 2006 outbreak in Saskatchewan.
The Canadian veterinary journal = La revue veterinaire canadienne    May 14, 2009   Volume 50, Issue 3 291-294 
Himsworth CG, Argue CK.Clinical signs and carcass traits observed during the 2006 Saskatchewan anthrax outbreak were largely consistent with those previously published, except for cutaneous anthrax and anthrax mastitis in cows, and subcutaneous edema in bulls and horses. Failure of blood to clot was the most reliable indicator of anthrax in carcasses. Impressions cliniques de l’anthrax lors de l’éclosion de 2006 en Saskatchewan. Les signes cliniques et les caractéristiques des carcasses observés durant l’éclosion d’anthrax en Saskatchewan en 2006 étaient généralement similaires à ceux déjà publiés...
[Antiparasitic treatments and the prescription obligation for horses].
Tijdschrift voor diergeneeskunde    May 13, 2009   Volume 134, Issue 7 288-295 
Sloet van Oldruitenborgh-Oosterbaan MM, van Doorn DC, Holland W, van Herten J, Ploeger HW, Fink-Gremmels J.In dit artikel wordt alle regelgeving betreffende de receptplicht op een rijtje gezet, een kort overzicht gegeven van endoparasieten en hun bestrijding, en een leidraad gegeven van wat er van een 'redelijk bekwaam en redelijk handelend dierenarts' mag worden verwacht. De ecto-parasieten zijn in dit artikel buiten beschouwing gelaten, omdat daar-voor eigenlijk geen receptplichtige middelen beschikbaar zijn en dit onderwerp al uitgebreid is besproken in de 'Leidraad Infectieuze Aan-doeningen – Huid' (Tijdschr. Dier-geneeskd. 2008; 113: 388-392).
Diseases in neonatal foals. Part 2: potential risk factors for a higher incidence of infectious diseases during the first 30 days post partum.
Equine veterinary journal    May 8, 2009   Volume 41, Issue 2 186-191 doi: 10.2746/042516408x345143
Wohlfender FD, Barrelet FE, Doherr MG, Straub R, Meier HP.The development of clinical illness in foals is usually predetermined by perinatal history, management or stressful environmental conditions. Objective: To determine potential risk factors for an increased incidence of infectious diseases during the first 30 days post partum. Methods: The population consisted of Thoroughbred foals born on stud farms in the Newmarket (UK) area in 2005 (n = 1031). They were followed for their first 30 days. Factors suspected to influence the incidence of infectious neonatal diseases were examined in a logistic regression approach for each of the 3 outcomes (tota...
AAEP releases guidelines on protecting thoroughbred health.
Journal of the American Veterinary Medical Association    April 14, 2009   Volume 234, Issue 7 856-857 
Osborne M.No abstract available
A perspective on Theileria equi infections in donkeys.
The Japanese journal of veterinary research    April 11, 2009   Volume 56, Issue 4 171-180 
Kumar S, Kumar R, Sugimoto C.The donkey population has remained unchanged in the last two decades despite a decrease in the overall population of equids, emphasizing the usefulness of the donkey as a draught and pack animal. Piroplasmosis in donkeys, caused by Theileria equi and Babesia caballi, has been recognized as a serious problem of major economic importance as the affected animals manifest decreased working capacity, loss of appetite, etc. In tropical countries, T. equi infections are more wide-spread and pathogenic than those caused by B. caballi. Donkeys usually remain asymptomatic carriers with positive antibody...
[Equine Infectious Anemia (EIA)].
Schweizer Archiv fur Tierheilkunde    April 1, 2009   Volume 151, Issue 4 159-164 doi: 10.1024/0036-7281.151.4.159
Kaiser A, Meier HP, Straub R, Gerber V.Equine Infectious Anemia (EIA) is a reportable, eradicable epizootic disease caused by the equine lentivirus of the retrovirus family which affects equids only and occurs worldwide. The virus is transmitted by blood, mainly by sanguivorous insects. The main symptoms of the disease are pyrexia, apathy, loss of body condition and weight, anemia, edema and petechia. However, infected horses can also be inapparent carriers without any overt signs. The disease is diagnosed by serological tests like the Coggins test and ELISA tests. Presently, Switzerland is offi cially free from EIA. However, Switz...
Control of equine influenza: scenario testing using a realistic metapopulation model of spread.
Journal of the Royal Society, Interface    April 1, 2009   Volume 7, Issue 42 67-79 doi: 10.1098/rsif.2009.0030
Baguelin M, Newton JR, Demiris N, Daly J, Mumford JA, Wood JL.We present a metapopulation model of the spread of equine influenza among thoroughbred horses parametrized with data from a 2003 outbreak in Newmarket, UK. The number of horses initially susceptible is derived from a threshold theorem and a published statistical model. Two simulated likelihood-based methods are used to find the within- and between-yard transmissions using both exponential and empirical latent and infectious periods. We demonstrate that the 2003 outbreak was largely locally driven and use the parametrized model to address important questions of control. The chance of a large ep...
The continuous spread of West Nile virus (WNV): seroprevalence in asymptomatic horses.
Epidemiology and infection    March 17, 2009   Volume 137, Issue 8 1163-1168 doi: 10.1017/S0950268809002325
Alonso-Padilla J, Loza-Rubio E, Escribano-Romero E, Córdoba L, Cuevas S, Mejía F, Calderón R, Milián F, Travassos Da Rosa A, Weaver SC....West Nile virus (WNV) was probably introduced in southern and northern Mexico from the USA in two independent events. Since then, WNV activity has been reported in several Mexican states bordering the USA and the Gulf of Mexico, but disease manifestations seen there in humans and equids are quite different to those observed in the USA. We have analysed WNV seroprevalence in asymptomatic, unvaccinated equids from two Mexican states where no data had been previously recorded. WNV IgG antibodies were detected in 31.6% (91/288) of equine sera from Chiapas and Puebla states (53.3% and 8.0%, respect...
A molecular survey of Piroplasmida and Hepatozoon isolated from domestic and wild animals in Burgos (northern Spain).
Veterinary parasitology    February 26, 2009   Volume 162, Issue 1-2 147-150 doi: 10.1016/j.vetpar.2009.02.021
Gimenez C, Casado N, Criado-Fornelio A, de Miguel FA, Dominguez-Peñafiel G.This study reports a molecular survey of Hepatozoon species and of the order Piroplasmida in the Province of Burgos, northern Spain. The diagnostic techniques employed included PCR and the sequencing of the 18S rRNA gene. Eighty-nine blood samples from domestic animals plus 138 blood/coagulated blood samples from wild mammals were examined. Theilerid protozoa were found at relatively high frequencies in bovines (14.6%) and horses (36%). Theileria buffeli, T. sergenti and T. annulata were diagnosed in cows. T. equi was common in horses and T. annae was found in a donkey for the first time. A ne...
Application of an automated surveillance-data-analysis system in a laboratory-based early-warning system for detection of an abortion outbreak in mares.
American journal of veterinary research    February 24, 2009   Volume 70, Issue 2 247-256 doi: 10.2460/ajvr.70.2.247
Odoi A, Carter CN, Riley JW, Smith JL, Dwyer RM.To develop an early-warning automated surveillance-data-analysis system for early outbreak detection and reporting and to assess its performance on an abortion outbreak in mares in Kentucky. Methods: 426 data sets of abortions in mares in Kentucky during December 2000 to July 2001. Methods: A custom software system was developed to automatically extract and analyze data from a Laboratory Information Management System database. The software system was tested on data on abortions in mares in Kentucky reported between December 1, 2000, and July 31, 2001. The prospective space-time permutations sc...
Analysis of local spread of equine influenza in the Park Ridge region of Queensland.
Transboundary and emerging diseases    February 10, 2009   Volume 56, Issue 1-2 31-38 doi: 10.1111/j.1865-1682.2008.01060.x
Davis J, Garner MG, East IJ.In 2007, an incursion of equine influenza (EI) occurred in Australia. Accurate maps of property boundaries were used to examine the pattern and mechanism of local spread of EI. This study focussed on a cluster of infected premises (IPs) at Park Ridge, a peri-urban suburb 26 km south of Brisbane, Queensland. The cluster recorded 437 IPs and 81% of these were not contiguous to a previously IP. The mean distance from each new IP to the closest previous IP was 0.85 +/- 1.50 km with a range of 0.01-12.94 km. Eighty-two percent of new IPs were within 1 km of a previous IP. The spatial mean for each ...
Clonal spread of methicillin-resistant coagulase-negative staphylococci among horses, personnel and environmental sites at equine facilities.
Veterinary microbiology    January 30, 2009   Volume 137, Issue 3-4 397-401 doi: 10.1016/j.vetmic.2009.01.034
Moodley A, Guardabassi L.A cross-sectional study was carried out to investigate species distribution and clonality of methicillin-resistant coagulase-negative staphylococci (MRCoNS) isolated from the nasal cavity of 39 horses and 32 veterinary or caretaker staff, and from 76 environmental surfaces at three equine facilities in Denmark. MRCoNS obtained by selective isolation were characterised by 16S rDNA sequencing, PCR detection of mecA, and pulsed-field gel electrophoresis (PFGE). MRCoNS were found in 32 (82%) horses, 20 (63%) humans and 50 (66%) environmental samples. The most common species was S. vitulinus (n=56)...
Irrigation linked to a greater incidence of human and veterinary West Nile virus cases in the United States from 2004 to 2006.
Preventive veterinary medicine    January 30, 2009   Volume 89, Issue 1-2 134-137 doi: 10.1016/j.prevetmed.2008.12.004
Gates MC, Boston RC.Identifying risk factors for West Nile virus transmission is vital for future public health control measures. This study investigated the effect of irrigation, expressed as percent irrigated land, and population density on the incidence of human and veterinary West Nile virus (WNV) cases using a sample of 2827 counties from the United States over a 3-year period. Zero-inflated Poisson regression models were selected because of the large number of counties reporting zero cases. The mean percentage of irrigated land for the entire sample was approximately 0.029, while counties reporting both hum...
Trichinella britovi and Trichinella spiralis mixed infection in a horse from Poland.
Veterinary parasitology    January 24, 2009   Volume 161, Issue 3-4 345-348 doi: 10.1016/j.vetpar.2009.01.013
Liciardi M, Marucci G, Addis G, Ludovisi A, Gomez Morales MA, Deiana B, Cabaj W, Pozio E.Trichinella infections in horses continue to represent a health problem and, despite the rarity of infection, it is necessary to continue to control properly horse meat. In 2008, a 10-year-old horse imported from Poland to Italy for consumption found to have been positive at the digestion test. Both Trichinella britovi and Trichinella spiralis larvae in a proportion of 4:1 were detected in the horse muscles. This is the first report of a mixed Trichinella species infection in a horse. The epidemiological investigation revealed that the infected horse originated from a small farm about 120km fr...
An outbreak of equine infectious anaemia in Ireland during 2006: investigation methodology, initial source of infection, diagnosis and clinical presentation, modes of transmission and spread in the Meath cluster.
Equine veterinary journal    January 24, 2009   Volume 40, Issue 7 706-708 doi: 10.2746/042516408x363305
More SJ, Aznar I, Bailey DC, Larkin JF, Leadon DP, Lenihan P, Flaherty B, Fogarty U, Brangan P.No abstract available
Detection of virulent Rhodococcus equi in exhaled air samples from naturally infected foals.
Journal of clinical microbiology    January 14, 2009   Volume 47, Issue 3 734-737 doi: 10.1128/JCM.01395-08
Muscatello G, Gilkerson JR, Browning GF.Virulent Rhodococcus equi causes pyogranulomatous bronchopneumonia in foals. The route of infection of foals has been considered to be inhalation of aerosolized bacteria from soil that is contaminated with equine feces. Thus, disease caused by R. equi has been regarded as an opportunistic infection of environmental origin and not a contagious disease. In this study, we report the exhalation of virulent R. equi from the respiratory tract of naturally infected foals. A handheld air-monitoring system was used to recover virulent R. equi from the exhaled breath of foals, and the concentration of v...
Epidemiologic analysis of nosocomial Salmonella infections in hospitalized horses.
Journal of the American Veterinary Medical Association    January 6, 2009   Volume 234, Issue 1 108-119 doi: 10.2460/javma.234.1.108
Ekiri AB, MacKay RJ, Gaskin JM, Freeman DE, House AM, Giguère S, Troedsson MR, Schuman CD, von Chamier MM, Henry KM, Hernandez JA.To examine the relationship between abdominal surgery and nosocomial Salmonella infections and the relationship between high caseload in combination with abdominal surgery and nosocomial Salmonella infections in hospitalized horses with signs of gastrointestinal tract disease. Methods: 140 horses. Methods: Case-control study. Methods: To accomplish the first objective, 1 to 4 control horses were matched with each nosocomial case horse on the basis of admission date of a primary case horse. The frequency of abdominal surgery and other investigated exposure factors were compared between nosocomi...
Effect of Amblyomma cajennense ticks on the immune response of BALB/c mice and horses.
Annals of the New York Academy of Sciences    January 6, 2009   Volume 1149 230-234 doi: 10.1196/annals.1428.028
Castagnolli KC, Ferreira BR, Franzin AM, de Castro MB, Szabó MP.This work evaluated the effect of the Amblyomma cajennense tick on the immune response of BALB/c mice and on horse lymph node cell proliferation. We observed that mice do not develop resistance to nymphs of this tick species and that lymphocyte proliferation of this host is inhibited by tick saliva, nymphal extract, or infestations. Horse lymph node cell proliferation is inhibited by tick saliva as well. Mice lymphocytes under the effect of tick saliva, nymphal extract, or infestations display a predominantly Th-2 cytokine production pattern. Observed results partially explain this tick's dise...
Development of an indirect ELISA for the diagnosis of equine piroplasmosis.
Annals of the New York Academy of Sciences    January 6, 2009   Volume 1149 235-238 doi: 10.1196/annals.1428.029
Asenzo G, Wilkowsky S, Barrandeguy M, Mesplet M, Benitez D, Florin-Christensen M.An indirect ELISA (iELISA) for the detection of specific anti-Theileria equi antibodies in horse serum was developed. Its performance showed good concordance (K= 0.79) when compared with a competitive ELISA recommended by the World Organisation for Animal Health. Horse serum samples from two provinces located in the north and east of Argentina (Formosa and Entre Rios, respectively) were analyzed by this iELISA. A high percentage of positive horses were found in Formosa, consistent with the climatic conditions of the region that are apt for the development of tick vectors. Surprisingly, seropos...
[Anti-influenza vaccination in animals].
Bulletin et memoires de l'Academie royale de medecine de Belgique    January 1, 2009   Volume 164, Issue 10 275-282 
Bublot M.Until recently, Influenza was considered as a veterinary problem in avian, swine and horse only. New influenza strains able to infect and cause a disease in dogs and cats emerged these last six years. The most widely used influenza veterinary vaccines are the inactivated adjuvanted vaccines which are based on whole or split virus. New technologies have allowed the development of new generation vaccines including modified-live and vector vaccines. Modified-live influenza vaccines are available for horses only but they are in development in other species. Vector vaccines are already in use in ch...
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