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Topic:Draft Horses

Draft horses are a type of horse bred primarily for heavy work, such as plowing and hauling, due to their large size and strength. They are characterized by their muscular build, calm temperament, and considerable pulling power. Common breeds of draft horses include the Belgian, Clydesdale, Percheron, and Shire. These horses have historically been used in agriculture, logging, and transportation before the advent of mechanized vehicles. This page compiles peer-reviewed research studies and scholarly articles that explore the breeding, physiology, and historical roles of draft horses, as well as their modern applications in various industries and recreational activities.
The Differences in Histoarchitecture of Hoof Lamellae between Obese and Lean Draft Horses.
Animals : an open access journal from MDPI    July 11, 2022   Volume 12, Issue 14 1774 doi: 10.3390/ani12141774
Senderska-Płonowska M, Siwińska N, Zak-Bochenek A, Rykała M, Słowikowska M, Madej JP, Kaleta-Kuratewicz K, Niedźwiedź A.Obesity is a common problem in horses. The associations between obesity and equine metabolic syndrome (EMS) and between EMS and laminitis are known. However, there is a lack of data on whether obesity itself can affect hoof lamellae. Forelimbs and blood from 12 draft horses (six obese and six lean) from a slaughterhouse were acquired. To exclude laminitis and EMS horses, insulin concentration was measured, and hooves were radiographed. Histological evaluation was performed. The shape of the primary and secondary epidermal lamellae (PEL and SEL) was evaluated, and the length of the keratinized ...
Survey of ocular abnormalities in draft horses.
Veterinary ophthalmology    June 30, 2022   Volume 26, Issue 2 101-107 doi: 10.1111/vop.13009
Sheridan CK, Myrna KE, Nunnery CM, Czerwinski SL.To determine the prevalence of ocular disease in draft horses in the United States. Methods: Draft horses of various breeds and ages. Methods: Nondilated ophthalmic examination was performed using slit lamp biomicroscopy and indirect ophthalmoscopy. Intraocular pressures were measured when possible. Results: One hundred sixty-five draft horses were examined. Age range: 10 days to 33 years (mean 10.8 years, median 10 years); 87 geldings (52.7%), 71 mares (43.0%), 7 stallions (4.2%); 64 Percherons (38.8%), 51 Belgians (30.9%), 29 Clydesdales (17.6%), 15 Shires (9%), and 6 other draft bre...
Epidemiological survey, general blood biochemistry, and histological examination of slaughtered heavy horse breeds with hemorrhage in the adipose tissue in the crest of the neck.
Journal of equine science    April 19, 2022   Volume 33, Issue 1 7-12 doi: 10.1294/jes.33.7
Harada K, Kanemitsu S, Akioka K, Fujita K, Nishi Y, Taura Y, Sasaki N.Fifty-four slaughtered horses were classified into groups having adipose tissue in the crest of the neck with or without hemorrhage (AH and NH groups, respectively). Blood biochemical tests (Alb, TP, T-bil, GOT, GPT, LDH, T-cho, and BUN) and an epidemiological survey (age, gender, weight, origin, breed, BCS, CNS, and hoof disease) were performed. T-bil tended to be high, while the other parameters were normal. Weight, BCS, and CNS were higher in the AH group (P<0.05). GOT was lower in the AH group (P<0.05). It was suspected that the horses in the AH group had lipomatosis. It was assumed ...
Influence of Obesity on Histological Tissue Structure of the Cardiovascular System in Horses.
Animals : an open access journal from MDPI    March 15, 2022   Volume 12, Issue 6 732 doi: 10.3390/ani12060732
Siwinska N, Janus I, Zak-Bochenek A, Noszczyk-Nowak A.It has been well established that obesity in horses can have a negative impact on their health, including endocrine disturbances. In humans, it is well known that obesity leads to structural and functional changes of the cardiovascular system. The aim of the study was to assess the impact of obesity on the histological structure of the myocardial tissue, as well as great and peripheral arteries in horses. The heart, arteries (aorta, pulmonary artery and palmar arteries) specimens from 7 horses with normal BCS (4-5/9) and 12 extremely obese (BCS 9/9) draft slaughter horses were obtained for his...
Equine nonneoplastic abnormal ovary in a draft mare with high serum anti-Müllerian hormone: a case study.
Journal of equine science    December 28, 2021   Volume 32, Issue 4 147-151 doi: 10.1294/jes.32.147
Goto A, Tagami M, Kato F, Suzuki T, Yamaga T, Murase H, Sato F, Tsogtgerel M, Niikura T, Moriyama T, Chiba A, Watanabe KI, Tsuzuki N, Nambo Y.We performed a standing hand-assisted laparoscopic ovariectomy in a draft mare that presented with high serum anti-Müllerian hormone (AMH) level and had an enlarged single cystic ovary. Histopathological examination revealed no tumor cell proliferation in the ovary, but the presence of a large ovarian cyst was confirmed. In the diagnosis of abnormal ovaries in mares, a comprehensive assessment should be performed, including the monitoring of ovarian morphology and biomarkers over time, to determine the disease prognosis and treatment plan. The case of this mare with a nonneoplastic abnormal o...
Effect of prostaglandin F2α administration on uterine polymorphonuclear neutrophil counts in Japanese heavy draft horses.
Journal of equine science    December 28, 2021   Volume 32, Issue 4 117-124 doi: 10.1294/jes.32.117
Niikura T, Tsogtgerel M, Niikura C, Wada H, Kanzawa S, Fujiwara T, Nambo Y.The objective of this study was to examine the effect of prostaglandin F2α (dinoprost) and oxytocin administration on uterine polymorphonuclear neutrophil counts in the Japanese heavy draft mare. To compare polymorphonuclear neutrophil (PMN) counts in the endometrium, a total of 162 samples were collected from 54 estruses of 47 mares (before ovulation, day 0, and day 2) using a double-guarded cytology brush. Dinoprost (PG; 5 mg) was administered intramuscularly (i.m.) only once, on day 0, whereas oxytocin (OT; 20 U i.m.) was administered three times at 12-hr intervals starting on day 0. The p...
[Seroprevalence of Leptospira spp. in draft horses from indigenous communities in the Araucanía Region, Chile].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia    October 16, 2021   Volume 38, Issue 4 580-582 doi: 10.4067/S0716-10182021000400580
Tuemmers C, Quezada G, Morales R, Serri M.In the Araucanía Region there are no studies on the seroprevalence of leptospirosis in horses. Serological samples from 100 draft horses from Mapuche communities of four communes in the region were analyzed using the microMAT technique. The seroprevalence was 35% for at least one serovar of Leptospira spp. being the most frequent serovars canicola (22%), grippotyphosa (21%), hardjo (13%) and pomona (10%). It was evident that the equine populations studied are exposed to infection by Leptospira spp. and reveal a potential risk of transmission to their owners.
Proteomic analysis to understand the relationship between the sarcoplasmic protein patterns and meat organoleptic characteristics in different horse muscles during aging.
Meat science    September 26, 2021   Volume 184 108686 doi: 10.1016/j.meatsci.2021.108686
The study investigates the changes in meat organoleptic characteristics and sarcoplasmic proteins of 3 horse muscles during aging. Longissimus lumborum (LL), semimembranosus (SM) and semitendinosus (ST) muscles, were removed from 12 Italian Heavy Draft Horse carcasses and aged for 1, 3, 6, 9 and 14 days. The lowest values of hardness and chewiness were found in LL muscle. During aging, a decrease of hardness was observed in ST muscle reaching the lowest value at 14 days. 2DE revealed a decrease of 15 sarcoplasmic protein spots in all muscles. Muscle-differences were found at 14 days. An inc...
The Use of Draught Animals in Rural Labour.
Animals : an open access journal from MDPI    September 13, 2021   Volume 11, Issue 9 2683 doi: 10.3390/ani11092683
Mota-Rojas D, Braghieri A, Álvarez-Macías A, Serrapica F, Ramírez-Bribiesca E, Cruz-Monterrosa R, Masucci F, Mora-Medina P, Napolitano F.This study discusses scientific findings on the use of draught animals such as equids (i.e., horses, mules, and donkeys) and bovids (i.e., cattle and water buffaloes) in rural labours. Relevant peer-reviewed literature published between 1980 and 2021 was retrieved from CAB Abstracts, PubMed, ISI Web of Knowledge, and Scopus databases. Although animals were used to produce draught power since their domestication and are still being used for this purpose, mechanisation has markedly reduced animal labour demand in agriculture. However, the process was uneven across continents according to economi...
A cross-sectional study of Leishmania spp. in draft horses from the Distrito Federal, Brazil: Seroprevalence, spatial distribution, and associated factors.
Preventive veterinary medicine    August 17, 2021   Volume 195 105467 doi: 10.1016/j.prevetmed.2021.105467
Biral NV, Azevedo Santos H, Senne NA, Paulino PG, Camilo TA, Tassinari WS, Silva VL, Santos FN, Angelo IDC.Equine leishmaniasis is a neglected tropical disease caused by the protozoan of the Leishmania genus, and it has been reported in several countries around the world, especially Brazil. Therefore, the present investigation aims to conduct a cross-sectional study to determine the prevalence, spatial distribution, and associated factors with seropositivity for Leishmania spp. in draft horses from the Distrito Federal, Brazil. The serological survey was conducted on 411 animals, employing the Indirect Immunofluorescence Test (IFA) and Enzyme-Linked Immunosorbent Assay (ELISA). The Kappa (κ) and g...
Case report: The case of a 17 kg ovarian granulosa cell tumor in a Breton draft mare.
Journal of equine science    June 18, 2021   Volume 32, Issue 2 67-72 doi: 10.1294/jes.32.67
Tsogtgerel M, Tagami M, Watanabe K, Murase H, Hirosawa Y, Kobayashi Y, Nambo Y.Granulosa cell tumor (GCT) is a benign tumor which affects the mare's ovaries. In this report, a case of unilateral GCT in an ovary, which weighed 17.04 kg, of a 9-year-old Breton draft mare is described. A transrectal ultrasonography exam revealed a unilateral multi-cystic enlarged ovary. Laparoscopic ovariectomy was difficult due to enlargement of blood vessels in the ovarian broad ligament. The mare was necropsied, and the pathological changes in the GCT-affected ovary and unaffected ovary were evaluated. The ovarian mass in the GCT-affected ovary had a cribriform pattern and was positive f...
Investigation of erythrocyte antigen frequencies in draft horse populations in Japan to assess blood donor suitability.
Journal of equine science    March 16, 2021   Volume 32, Issue 1 17-19 doi: 10.1294/jes.32.17
Kakoi H, Kikuchi M, Ishige T, Nagata SI, Hirosawa Y, Tanaka S, Kishinami T.Erythrocyte alloantigen frequencies of draft horses in Japan were investigated to assess blood donor suitability for transfusion. Here, 148 Japanese draft, 69 Percheron, and 65 Breton horses were blood-typed and subjected to an indirect antiglobulin test. Regarding the major immunogenic factors, the rates of Aa- and Qa-negative horses ranged from 0.35 to 0.49 and from 0.82 to 1.00, respectively. The rate of alloantibody-positive horses ranged from 0.12 to 0.35. Although the prevalence of alloantibodies in these horses was higher than that expected naturally, the rates of Aa- and Qa-negative ho...
Symmetric dimethylarginine and creatinine concentrations in serum of healthy draft horses.
Journal of veterinary internal medicine    February 5, 2021   Volume 35, Issue 2 1147-1154 doi: 10.1111/jvim.16042
Schott HC, Gallant LR, Coyne M, Murphy R, Cross J, Strong-Townsend M, Szlosek D, Yerramilli M, Li J.Symmetric dimethylarginine (SDMA) is considered a more sensitive indirect estimate of glomerular filtration rate (GFR) than creatinine (Cr). Symmetric dimethylarginine is not affected by sex or muscle mass in small animals. Objective: To validate a commercial SDMA immunoassay (IA) for equine serum; to compare SDMA and Cr in cohorts of draft horse breeds; and to assess effects of age, sex, and breed. Methods: One hundred and sixty-five healthy draft horses (0.5-16 years), including 63 Percherons, 52 Clydesdales, and 50 Belgians. Methods: Cross-sectional study. The SDMA IA was validated for eq...
Arbovirus serosurvey (Orthobunyavirus, Flavivirus, and Alphavirus) in a draft horse population from Santa Fe, Argentina (2013-2016).
Archives of virology    January 12, 2021   Volume 166, Issue 3 881-884 doi: 10.1007/s00705-020-04929-4
In the present study, we serosurveyed the exposure of 222 draft horses to different arboviruses in the city of Santa Fe, Argentina. Plaque reduction neutralization tests confirmed exposure to Fort Sherman virus (FSV), Saint Louis encephalitis virus (SLEV), West Nile virus (WNV), and Río Negro virus (RNV). Apparently, Western and Eastern equine encephalitis viruses did not circulate in the population tested. The confirmation of five seroconversions for WNV, FSV, and SLEV and the association between prevalence and age are indicative of recent circulation. These results highlight the importance ...
Chronic Collateral Sesamoidean Desmopathy in Draft Horses: Magnetic Resonance Imaging and Histopathological Findings.
Journal of equine veterinary science    January 7, 2021   Volume 98 103362 doi: 10.1016/j.jevs.2020.103362
Abu-Seida AM, Elemmawy YM.Desmopathy of the collateral sesamoidean ligament (CSL) is an unusual disorder in draft horses. This study records the magnetic resonance imaging (MRI) features of chronic CSL desmopathy in eight draft horses and confirms these features by histopathology. The recorded chronic CSL desmopathy has usually affected the forelimbs (100%) and commonly bilateral (62.5%). All horses showed positive proximal digital nerve block, positive front digital flexion test, and negative interphalangeal extension test. Radiography revealed no osseous abnormalities in all feet. MRI features of chronic CSL desmopat...
Variability of ACOX1 Gene Polymorphisms across Different Horse Breeds with Regard to Selection Pressure.
Animals : an open access journal from MDPI    November 27, 2020   Volume 10, Issue 12 2225 doi: 10.3390/ani10122225
Myćka G, Musiał AD, Stefaniuk-Szmukier M, Piórkowska K, Ropka-Molik K.The gene encodes peroxisomal acyl-coenzyme A oxidase 1, the first enzyme in the fatty acid β-oxidation pathway, which could be significant for organisms exposed to long periods of starvation and harsh living conditions. We hypothesized that variations within , revealed by RNA Sequencing (RNA-Seq), might be based on adaptation to living conditions and had resulted from selection pressure. There were five different horse breeds used in this study, representing various utility types: Arabian, Thoroughbred, Polish Konik, draft horses, and Hucul. The single-nucleotide polymorphism (SNP) located i...
Urogenital Hypoplasia and X Chromosome Monosomy in a Draft Horse Filly.
Journal of equine veterinary science    November 10, 2020   Volume 96 103318 doi: 10.1016/j.jevs.2020.103318
Hahn K, Conze TM, Wollanke B, Distl O, Goehring LS, Witte TS.A 5-month-old draft horse filly was presented with incontinence and severe perivulvar dermatitis, which developed during the previous 2 months. Left-sided ectopic ureter entering in the caudal vaginal lumen, signs of cervix hypoplasia, and urine accumulation in the uterus were found during initial vaginal endoscopy. Therefore, a left ureter-nephrectomy was conducted under general anesthesia. Additionally, a cytogenetic examination was performed, which showed a XO monosomy with a 63,X/64,XX mosaic. This is the first case report presenting a chromosome abnormality in a draft horse filly combine...
Semen quality and freezability analysis during breeding and non-breeding seasons in heavy draft stallions in southern Chile.
Andrologia    September 1, 2020   Volume 52, Issue 11 e13797 doi: 10.1111/and.13797
Ebel F, Vallejos A, Gajardo G, Ulloa O, Clavel E, Rodríguez-Gil JE, Ramírez-Reveco A.The aim of this study was to evaluate seasonal changes in basic parameters of sperm quality and freezability behaviour of ejaculates from 10 fertile heavy draft stallions. A total of 140 ejaculates were collected, processed and evaluated during both the breeding (September-November) and non-breeding seasons (April-June). Fresh semen was evaluated for volume, concentration, total spermatozoa per ejaculate, plasma membrane integrity and total sperm motility. Cryopreserved samples were evaluated for plasma membrane integrity and sperm motility by the CASA system, and for the freezability index (F...
Is similarity in Major Histocompatibility Complex (MHC) associated with the incidence of retained fetal membranes in draft mares? A cross-sectional study.
PloS one    August 17, 2020   Volume 15, Issue 8 e0237765 doi: 10.1371/journal.pone.0237765
Jaworska J, Tobolski D, Janowski T.The failure of the maternal immune system to recognize fetal antigens and vice versa due to MHC similarity between the foal and its dam might result in the lack of placental separation during parturition in mares. The aim of the study was to investigate the influence of MHC similarity between a mare and a foal on the incidence of retained fetal membranes (RFM) in post-partum mares. DNA was sampled from 43 draft mares and their foals. Mares which failed to expel fetal membranes within three hours after foal expulsion were considered the RFM group (n = 14) and mares that expelled fetal membranes...
Colostral and foal serum immunoglobulin G levels and associations with perinatal abnormalities in heavy draft horses in Japan.
Journal of equine science    June 24, 2020   Volume 31, Issue 2 29-34 doi: 10.1294/jes.31.29
Aoki T, Chiba A, Itoh M, Nambo Y, Yamagishi N, Shibano KI, Cheong SH.The purpose of this study was to elucidate the colostral and foal serum immunoglobulin G (IgG) concentration values in heavy draft horses in Japan and to examine the effects of peripartum mare condition on colostral immunity. Colostrum was obtained 1 hr after foaling (pre-suckling; n=178). Blood was collected from the jugular vein of the foals (n=147) at 24 to 48 hr after birth. The foaling statuses of 73 mares were recorded. The average colostral IgG concentration was 10,540 ± 3,190 mg/dl (median=10,928; range 1,434-17,514 mg/dl). The average serum IgG concentration obtained from neonatal fo...
Mitochondrial DNA variation in the Italian Heavy Draught Horse.
PeerJ    May 15, 2020   Volume 8 e8996 doi: 10.7717/peerj.8996
Lancioni H, Cardinali I, Giontella A, Antognoni MT, Miglio A.In the last decades, Italy as well as other developed countries have registered a decrease in the population size of many local horse breeds. The continuous crossbreeding has determined the dilution of genetic heritage of several native breeds. The Italian Heavy Draught Horse (IHD) is the only autochthonous Italian coldblooded horse among these breeds; therefore, it represents a resource to be preserved. In 1927, the first generation of this breed was officially created by crossing different Heavy Draught horses with local mares and recorded in a Studbook. Methods: To provide the first compreh...
Antinociceptive Effect of Intravenous Regional Analgesia in Horses Underwent Selected Short-Time Distal Limb Surgeries.
Journal of equine veterinary science    May 6, 2020   Volume 91 103113 doi: 10.1016/j.jevs.2020.103113
Samy A, Elmetwally M, El-Khodery SA.The aim of the present study was to establish appropriate doses for both lidocaine hydrochloride (Hcl) and mepivacaine in intravenous regional analgesia (IVRA) and to assess their intraoperative and postoperative analgesic effects in horses with distal limb surgeries. A total of 55 draft horses were included in the present study. Six clinically healthy horses were selected randomly for establishing the doses of lidocaine Hcl and mepivacaine in IVRA in horse limbs. After selection, 32 horses suffered from various distal limb surgical affections were randomly allocated into three groups: thiopen...
Equine pythiosis in Egypt: clinicopathological findings, detection, identification and genotyping of Pythium insidiosum.
Veterinary dermatology    April 28, 2020   Volume 31, Issue 4 298-e73 doi: 10.1111/vde.12845
Tartor YH, Hamad MH, Abouzeid NZ, El-Belkemy FA.Equine pythiosis is an emerging, devastating disease that is hard to treat. The tumour-like nodular skin masses grow rapidly and the outcome is generally fatal, and thus early diagnosis and intervention are important. Objective: (i) To highlight the clinical, histological and haematological findings in pythiosis, and (ii) to evaluate the efficacy of direct sample multiplex-PCR targeting the single nucleotide polymorphisms within the ribosomal DNA region for detection and genotyping of Pythium insidiosum. Methods: Two hundred and twenty horses including 204 Arabian and 16 draft horses were surv...
Acute Life-threatening Laryngeal Dysfunction in a Draft Horse Recovering from General Anesthesia: A Case Report.
Journal of equine veterinary science    April 25, 2020   Volume 91 103109 doi: 10.1016/j.jevs.2020.103109
Ronaldson HL, Monticelli P, Smith R, Adami C.A 13-year-old Shire horse was anesthetized for an elective orthopedic procedure. During recovery from anesthesia, the occurrence of severe acute dyspnea required a second anesthetic to allow endoscopy-guided nasotracheal intubation. Endoscopic findings were decreased mobility and swelling of the arytenoids with narrowing of the laryngeal aditus. Owing to a dislodgement of the nasotracheal tube during recovery, a third anesthetic was carried out to perform emergency tracheostomy. Recovery from the third anesthetic was long and the horse developed a post-anesthetic myopathy. The clinical conditi...
A Field Study of Serum, Colostrum, Milk Iodine, and Thyroid Hormone Concentrations in Postpartum Draft Mares and Foals.
Journal of equine veterinary science    April 9, 2020   Volume 90 103018 doi: 10.1016/j.jevs.2020.103018
Lopez-Rodriguez MF, Cymbaluk NF, Epp T, Laarveld B, Thrasher M, Card CE.Iodine, thyroxine (T4) and triiodothyronine (T3) are required for normal fetal growth, maturation, and neonatal survival. There is a lack of robust information on iodine levels found in colostrum, milk, and serum of mares and foals after a healthy pregnancy. Our objective was to characterize colostrum, milk, and serum iodine levels in healthy postpartum mares and foals (n = 10) and explore relationships with thyroid hormone concentrations. Colostrum, milk, and jugular blood samples from draft breed mares and foals with an estimated average iodine daily intake of 39 mg per mare during pregnan...
Genetic Differentiation of the Two Types of Polish Cold-blooded Horses Included in the National Conservation Program.
Animals : an open access journal from MDPI    March 24, 2020   Volume 10, Issue 3 542 doi: 10.3390/ani10030542
Gurgul A, Jasielczuk I, Semik-Gurgul E, Pawlina-Tyszko K, Szmatoła T, Polak G, Bugno-Poniewierska M.The current role of the horse as a companion animal resulted in a decrease of interest in breeding and usage of draft horses. This meant that the population of cold-blooded horses in Poland has been dramatically reduced during the last decades. To avoid impoverishment of the gene pool of the local horse population, a conservation program was established which involves draft horses and other local horse breeds. The draft horses bred in Poland can be subdivided in a few horse types of which the most widespread and consolidated are Sztumski and Sokólski horses. These two subpopulations are pheno...
Evaluation of cytokines and sialic acids contents in horses naturally infected with Theileria equi.
Comparative immunology, microbiology and infectious diseases    February 25, 2020   Volume 70 101453 doi: 10.1016/j.cimid.2020.101453
Mostafavi E, Esmaeilnejad B, Meysam Abtahi Foroushani S.This study was undertaken to assess the effects of T. equi infection on serum concentrations of some important cytokines including interferon-γ (IFN-γ), tumor necrosis factor-α (TNF-α), and interleukin-1 beta (IL-1β), IL-1α, IL-4, IL-6, IL-8, IL-10, IL-12α, IL-12β, IL-18, as well as total, protein and lipid binding sialic acids (TSA, PBSA and LBSA). Furthermore, any probable relation among the parasitemia, cytokines and sialic acids (SAs) were calculated using Pearson correlation and simple linear regression. Almost 300 draft horses (Kurdish-breed) with age of 3-4 years old from north-...
The oxytocin-prostaglandins pathways in the horse (Equus caballus) placenta during pregnancy, physiological parturition, and parturition with fetal membrane retention.
Scientific reports    February 7, 2020   Volume 10, Issue 1 2089 doi: 10.1038/s41598-020-59085-1
Rapacz-Leonard A, Leonard M, Chmielewska-Krzesińska M, Siemieniuch M, Janowski TE.Despite their importance in mammalian reproduction, substances in the oxytocin-prostaglandins pathways have not been investigated in the horse placenta during most of pregnancy and parturition. Therefore, we quantified placental content of oxytocin (OXT), oxytocin receptor (OXTR), and prostaglandin E2 and F2 alpha during days 90-240 of pregnancy (PREG), physiological parturition (PHYS), and parturition with fetal membrane retention (FMR) in heavy draft horses (PREG = 13, PHYS = 11, FMR = 10). We also quantified OXTR and prostaglandin endoperoxide synthase-2 (PTGS2) mRNA expression ...
Inter- and intrabreed diversity of the major histocompatibility complex (MHC) in primitive and draft horse breeds.
PloS one    February 3, 2020   Volume 15, Issue 2 e0228658 doi: 10.1371/journal.pone.0228658
Jaworska J, Ropka-Molik K, Wocławek-Potocka I, Siemieniuch M.Polymorphism of major histocompatibility complex (MHC) genes ensures effective immune responses against a wide array of pathogens. However, artificial selection, as performed in the case of domestic animals, may influence MHC diversity. Here, we investigate and compare the MHC diversity of three populations of horses, for which different breeding policies were applied, to evaluate the impact of artificial selection and the environment on MHC polymorphism. Samples of DNA were taken from 100 Polish draft horses, 38 stabled Konik Polski horses and 32 semiferal Konik Polski horses. MHC alleles and...
Chronic progressive lymphoedema in Friesian horses: suggestive phenotype of affected horses and genome-wide association study.
Veterinary dermatology    January 6, 2020   Volume 31, Issue 3 234-e51 doi: 10.1111/vde.12831
Affolter VK, Dalley B, Kass PH, Brown EA, Sonder C, Bannasch DL.Chronic progressive lymphoedema (CPL) is a disabling condition affecting various draft horse breeds, including Friesian horses. Objective: The high incidence of CPL in Friesian horses suggests a genetic component and a predisposing phenotype. Methods: For the genomic study, 26 affected and 19 control horses were evaluated. Body measurements were taken from 28 affected and nine control Friesian horses. Methods: Axiom® Equine Genotyping Array with a total of 307,474 single nucleotide polymorphism (SNPs) was used for the case/control genome-wide association study (GWAS). Height, weight and leg m...