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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Study of the hyaloid apparatus in the neonatal thoroughbred foal.
The Veterinary record    June 6, 2000   Volume 146, Issue 20 579-584 doi: 10.1136/vr.146.20.579
Munroe G.Over 80 per cent of 169 neonatal thoroughbred foals had some part of the hyaloid artery present bilaterally and its degree of completeness, colour and character was statistically symmetrical. The complete artery was present in over 60 per cent of the foals. The incidence of the hyaloid artery and its completeness, colour and character were related to the age of the foal. The hyaloid system atrophies in the early stages of the neonatal period and generally its presence did not cause any significant ocular problems. The presence and morphology of the posterior pupillary membrane was highly corre...
Cross-sectional study of faecal shedding of Giardia duodenalis and Cryptosporidium parvum among packstock in the Sierra Nevada Range.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 247-252 doi: 10.2746/042516400776563545
Atwill ER, McDougald NK, Perea L.Faecal specimens from 305 horses and mules used as packstock at one of 17 commercial or governmental (National Park Service, US Forest Service) operations were examined for Giardia duodenalis and Cryptosporidium parvum using immunofluorescent microscopy. Fourteen packstock (4.6%) were shedding G. duodenalis cysts, with herd-level prevalences ranging 0-22%. Number of packstock in the corral, size of corral and density of packstock in the corral were associated with the odds of shedding G. duodenalis cysts. None of the horses had detectable C. parvum oocysts. Assuming a sensitivity of at least 4...
Radiographic and clinical survey of degenerative joint disease in the distal tarsal joints in Icelandic horses.
Equine veterinary journal    June 3, 2000   Volume 32, Issue 3 268-272 doi: 10.2746/042516400776563590
Björnsdóttir S, Axelsson M, Eksell P, Sigurdsson H, Carlsten J.The prevalence of degenerative joint disease (DJD) in the distal tarsal joints and the relation between radiographic and clinical signs compatible with the disease were estimated in a population of Icelandic horses used for riding. The material consisted of 614 horses age 6-12 years (mean age = 7.9 years). Radiographs with 3 projections of each tarsus were made and a clinical examination, including palpation of the medial aspect of the distal tarsus and motion evaluation of the hindlimbs before and after a flexion test of the tarsus, was performed. Radiographic signs of DJD in the distal tarsa...
Diagnosis of emerging ehrlichial diseases of dogs, horses, and humans.
Journal of veterinary internal medicine    June 1, 2000   Volume 14, Issue 3 250-251 doi: 10.1111/j.1939-1676.2000.tb01162.x
Rikihisa Y.No abstract available
Detection and quantitation of Ehrlichia risticii genomic DNA in infected horses and snails by real-time PCR.
Veterinary parasitology    June 1, 2000   Volume 90, Issue 1-2 129-135 doi: 10.1016/s0304-4017(00)00227-2
Pusterla N, Leutenegger CM, Sigrist B, Chae JS, Lutz H, Madigan JE.A real-time quantitative PCR using the TaqMan fluorogenic detection system (TaqMan PCR) was established for identification of Ehrlichia risticii, the agent of Potomac horse fever (PHF). The TaqMan PCR identified an 85 base pair section of the 16S rRNA gene by use of a specific fluorogenic probe and two primers. This technique was specific for eight tested E. risticii strains. The TaqMan system identified 10 copies of a cloned section of the 16S rRNA gene of E. risticii. The sensitivity and specificity of the TaqMan PCR were similar to those of conventional nested PCR. The TaqMan PCR was evalua...
Ehrlichia equi infection of horses from Minnesota and Wisconsin: detection of seroconversion and acute disease investigation.
Journal of veterinary internal medicine    June 1, 2000   Volume 14, Issue 3 252-257 doi: 10.1892/0891-6640(2000)014<0252:eiohfm>2.3.co;2
Bullock PM, Ames TR, Robinson RA, Greig B, Mellencamp MA, Dumler JS.Equine granulocytic ehrlichiosis (EGE) is caused by infection with Ehrlichia equi. EGE has been reported primarily in northern California, where E equi is transmitted by the tick Ixodes pacificus. Reports of EGE and the emergence of human granulocytic ehrlichia in Minnesota prompted a seroprevalence study of E equi in horses of Minnesota and Wisconsin. Tick (Ixodes scapularis) endemic areas of Minnesota and Wisconsin were compared to nonendemic regions of Minnesota. Indirect fluorescent antibody was used to detect the presence of serum antibodies to E equi. Serum samples from healthy horses, 3...
Papillomatous pastern dermatitis with spirochetes and Pelodera strongyloides in a Tennessee Walking Horse. Rashmir-Raven AM, Black SS, Rickard LG, Akin M.Papillomatous digital dermatitis is a common disease in cattle. The pastern dermatitis observed in a horse shared many of the gross characteristics of papillomatous digital dermatitis in cattle. Lesions included a mixture of proliferative and erosive changes, with a verrucose appearance in some areas. Microscopic similarities included pseudoepitheliomatous and papillomatous epidermal hyperplasia with hyperkeratosis, spongiosis of the epidermis, and intraepidermal spirochetes. The horse was also concurrently infected with Pelodera strongyloides. Papillomatous digital dermatitis in cattle is ass...
Equine influenza vaccine efficacy: the significance of antigenic variation.
Veterinary microbiology    May 9, 2000   Volume 74, Issue 1-2 173-177 doi: 10.1016/s0378-1135(00)00177-2
Yates P, Mumford JA.To investigate the level of cross-protection induced by equine influenza H3N8 vaccines derived from different lineages, two studies have been carried out with ponies vaccinated with 'American-like' and 'European-like' vaccines and experimentally challenged with a European-like strain. The results demonstrated that equine influenza vaccines clearly protect against challenge with homologous virus if serum antibody titres are sufficiently high. On the other hand, protection is incomplete even when animals vaccinated with heterologous strains have comparative antibody levels. Nevertheless, the pro...
Oral vesicular lesions in horses without evidence of vesicular stomatitis virus infection.
Journal of the American Veterinary Medical Association    May 9, 2000   Volume 216, Issue 9 1399-1404 doi: 10.2460/javma.2000.216.1399
Kim L, Morley PS, McCluskey BJ, Mumford EL, Swenson SL, Salman MD.To report clinical and serologic findings in horses with oral vesicular lesions that were consistent with vesicular stomatitis (VS) but apparently were not associated with VS virus (VSV) infection. Methods: Serial case study. Methods: 8 horses. Methods: Horses were quarantined after appearance of oral lesions typical of VS. Severity of clinical signs was scored every 2 to 5 days for 3 months. Serum samples were tested for antibodies by use of competitive ELISA (cELISA), capture ELISA for IgM, serum neutralization, and complement fixation (CF). Virus isolation was attempted from swab specimens ...
Identification and phylogenetic comparison of Salem virus, a novel paramyxovirus of horses.
Virology    May 4, 2000   Volume 270, Issue 2 417-429 doi: 10.1006/viro.2000.0305
Renshaw RW, Glaser AL, Van Campen H, Weiland F, Dubovi EJ.A virus that could not be identified as a previously known equine virus was isolated from the mononuclear cells of a horse. Electron microscopy revealed enveloped virions with nucleocapsid structures characteristic of viruses in the Paramyxoviridae family. The virus failed to hemabsorb chicken or guinea pig red blood cells and lacked neuraminidase activity. Two viral genes were isolated from a cDNA expression library. Multiple sequence alignments of one gene indicated an average identity of 45% as compared to Morbillivirus N protein sequences. A weaker relationship was found with Tupaia paramy...
Factors associated with time until first race and career duration for Thoroughbred racehorses.
American journal of veterinary research    May 3, 2000   Volume 60, Issue 10 1196-1200 
Bailey CJ, Reid SW, Hodgson DR, Rose RJ.To determine whether sex or foaling period were associated with time to first race start and whether sex, age at time of first race start, or inter-race period were associated with career duration for Thoroughbred racehorses in Australia. Methods: 553 Thoroughbred racehorses. Methods: Race records through to the end of the 6-year-old racing season were obtained for each horse. Product-limit survival analysis was used to determine whether sex or foaling period was associated with time to first race start and whether sex or age at first race was associated with career duration. A Cox proportiona...
An equine herpesvirus 1 (EHV1) abortion storm at a riding school.
The veterinary quarterly    May 2, 2000   Volume 22, Issue 2 83-87 doi: 10.1080/01652176.2000.9695030
van Maanen C, Willink DL, Smeenk LA, Brinkhof J, Terpstra C.An outbreak of EHV1 abortions occurred at a riding school in The Netherlands in 1991. Seven of twelve pregnant mares aborted, and another foal died at 8 days of age. Six abortions occurred within 12 days in March after an initial abortion on 8 February. Four mares delivered live foals. Virological examination of four aborted foals revealed an EHV1 infection. Serological results for paired sera from 17 horses suggested, that the initial abortion on 8 February was the index case, and probably caused the other six abortions. The index case could well have been caused by reactivation of latent vir...
Development of a fluorescence polarization-based diagnostic assay for equine infectious anemia virus.
Journal of clinical microbiology    May 2, 2000   Volume 38, Issue 5 1854-1859 doi: 10.1128/JCM.38.5.1854-1859.2000
Tencza SB, Islam KR, Kalia V, Nasir MS, Jolley ME, Montelaro RC.The control of equine infectious anemia virus (EIAV) infections of horses has been over the past 20 years based primarily on the identification and elimination of seropositive horses, predominantly by a standardized agar gel immunodiffusion (AGID) assay in centralized reference laboratories. This screening for EIAV-seropositive horses has been to date hindered by the lack of a rapid diagnostic format that can be easily employed in the field. We describe here the development of a rapid solution-phase assay for the presence of serum antibodies to EIAV based on fluorescence polarization (FP) (pat...
Differentiation and genomic and antigenic variation among fetal, respiratory, and neurological isolates from EHV1 and EHV4 infections in The Netherlands.
The veterinary quarterly    May 2, 2000   Volume 22, Issue 2 88-93 doi: 10.1080/01652176.2000.9695031
van Maanen C, Vreeswijk J, Moonen P, Brinkhof J, de Boer-Luijtze E, Terpstra C.Ten monoclonal antibodies (MAbs) were produced against equine herpes virus type 1 (EHV1). Two appeared type-specific, while the other eight were directed against epitopes common to both EHV1 and EHV4. Two MAbs directed against the glycoprotein gp2 recognized linear epitopes, as demonstrated by Western blotting. With pools of type-specific MAbs, 282 field isolates were typed in an immunoperoxidase monolayer assay (IPMA). From a total of 254 fetal or neonatal isolates, 244 (96%) were typed as EHV1, whereas 14 out of 15 (93%) respiratory tract isolates were typed as EHV4. Surprisingly, 3 out of 1...
Antimicrobial resistance in bacteria from pets and horses.
Acta veterinaria Scandinavica. Supplementum    April 28, 2000   Volume 92 37-50 
Sternberg S.No abstract available
Equine vaccination.
Journal of veterinary internal medicine    April 20, 2000   Volume 14, Issue 2 221-222 
Horohov DW, Lunn DP, Townsend HG, Wilson D.No abstract available
Ataxia and paresis with equine herpesvirus type 1 infection in a herd of riding school horses.
Journal of veterinary internal medicine    April 20, 2000   Volume 14, Issue 2 197-201 doi: 10.1892/0891-6640(2000)014<0197:aapweh>2.3.co;2
Friday PA, Scarratt WK, Elvinger F, Timoney PJ, Bonda A.An outbreak of neurologic disease associated with serologic evidence of equine herpesvirus type 1 (EHV-1) infection occurred in a herd of 46 riding school horses. Ataxia and paresis were observed in 14 geldings and 5 barren mares. Eight affected horses had distal limb edema, 1 horse had a head tilt, and 3 others had urinary incontinence. Other clinical signs included fever, depression, and inappetance in 30 horses. Seven horses with neurologic signs were treated with acyclovir. Serum neutralizing antibody titers against EHV-1 increased 4-fold between acute and convalescent samples or exceeded ...
Urban carriage horses 1999–status and concerns.
Journal of the American Veterinary Medical Association    April 18, 2000   Volume 216, Issue 8 1261-1262 
Merriam JG.No abstract available
Association of high-speed exercise with racing injury in thoroughbreds.
Journal of the American Veterinary Medical Association    April 18, 2000   Volume 216, Issue 8 1273-1278 doi: 10.2460/javma.2000.216.1273
Cohen ND, Berry SM, Peloso JG, Mundy GD, Howard IC.To determine the association between high-speed exercise and risk of injury while racing among Thoroughbreds in Kentucky. Methods: Matched case-control study. Methods: 206 Thoroughbreds that sustained a musculoskeletal injury while racing and 412 Thoroughbreds that were not injured during the same races. Methods: Data regarding official timed workouts and races and the Beyer's numbers for the 3 races before the race during which injury occurred were extracted from past performance charts and compared between injured horses and control horses. Results: For injured horses, cumulative distance of...
The study of cutaneous melanomas in Camargue-type gray-skinned horses (2): epidemiological survey.
Pigment cell research    April 13, 2000   Volume 13, Issue 1 47-51 doi: 10.1034/j.1600-0749.2000.130109.x
Fleury C, Bérard F, Leblond A, Faure C, Ganem N, Thomas L.An epidemiological survey was made on cutaneous melanomas occurring in Camargue-type, gray-skinned horses in southern France. The population investigated was composed of 264 horses, which were selected from the Camargue horse stud registry and were allowed to be examined by the owners. The presence of tumors was inspected macroscopically according to the standardized protocols of veterinary medicine specialists, and some tumors were subjected to macroscopic histopathological examination. The results indicated that: 1) the prevalence of melanomas in the overall population was 31.4%; 2) the odds...
Characterization of trypanosome isolates from naturally infected horses on a farm in Kenya.
Veterinary parasitology    April 13, 2000   Volume 89, Issue 3 173-185 doi: 10.1016/s0304-4017(00)00195-3
Kihurani DO, Masake RA, Nantulya VM, Mbiuki SM.Following an outbreak of trypanosomosis in horses on a farm in Kenya, 18 trypanosome isolates were collected from the infected animals over a period of one and a half years and cryopreserved for characterization. The characterization was done on the basis of morphology using Giemsa-stained blood and buffy coat smears, infectivity to mice, recombinant DNA hybridization, and chromosome separation by orthogonal field alternation gel electrophoresis (OFAGE). Morphologically, all the trypanosome isolates were identified as belonging to the subgenus Nannomonas, and a total of 16 out of the 18 isolat...
Seasonal dynamics of Anocentor nitens on horses in Brazil.
Veterinary parasitology    April 13, 2000   Volume 89, Issue 3 165-171 doi: 10.1016/s0304-4017(00)00204-1
Borges LM, Oliveira PR, Ribeiro MF.Anocentor nitens is a widespread ectoparasite of horses in Brazil. A study of the seasonal dynamics of the parasitic phase of this tick was made by regular census of engorging females (>/=4mm) on free-ranging horses, fortnightly from July 1995 to July 1997, at Pedro Leopoldo, Minas Gerais. Twenty horses were divided into four groups of five animals per group, each having a similar mix of resistant and less resistant animals, based on initial infestation. Every 2 weeks, one of the groups, in sequence, was treated with an acaricide to prevent excessive infestations, and female ticks were cens...
Equine vaccination.
The Veterinary clinics of North America. Equine practice    April 7, 2000   Volume 16, Issue 1 199-viii doi: 10.1016/s0749-0739(17)30127-x
Lunn DP, Townsend HG.Equine infectious disease remains a constant and important threat to the health of domesticated horses. Vaccination plays a critical role in protecting against such disease, but at the present time the efficacy of some equine vaccination strategies is in doubt. The best strategy for resolving these concerns is an improved knowledge of the immunologic basis of successful vaccination, combined with the appropriate integration of effective vaccines into well-designed disease control policies.
Equine immunity to parasites.
The Veterinary clinics of North America. Equine practice    April 7, 2000   Volume 16, Issue 1 69-vi doi: 10.1016/s0749-0739(17)30119-0
Klei TR.Helminths are among the most significant parasites of horses in developed countries. This article examines immune responses against helminth parasites and the implications that immunologic investigations have on vaccine development, improvement of diagnostic procedures, and disease eradication.
[West Nile-like virus is the cause of encephalitis in humans and horses and the death of hundreds of birds in New York].
Tijdschrift voor diergeneeskunde    April 1, 2000   Volume 124, Issue 23 704-705 
van der Poel WH.No abstract available
Occurrence of Thelazia lacrymalis (Nematoda, Spirurida, Thelaziidae) in native horses in Abruzzo region (central eastern Italy).
Parasite (Paris, France)    April 1, 2000   Volume 7, Issue 1 51-53 doi: 10.1051/parasite/2000071051
Giangaspero A, Tieri E, Otranto D, Battistini ML.A survey on the prevalence of Thelazia spp. in Abruzzo region (Italy) in slaughtered native horses was conducted from August 29, 1997 to August 28, 1998. Both eyes from 128 eight-month to 11 year-old native animals were examined. 50 horses (39.06%) were found parasitized by Thelazia lacrymalis. 502 specimens (371 females, 88 males and 12 larvae) were collected. In the infected horses the numbers of T. lacrymalis ranged from 1 to 48, with a mean count burden of 3.92 per head (SD = 7.79). T. lacrymalis specimens were mainly in the excretory ducts of the Harderian gland, and also in the ducts of ...
Effects of density on displacement, falls, injuries, and orientation during horse transportation(1).
Applied animal behaviour science    March 29, 2000   Volume 67, Issue 3 169-179 doi: 10.1016/s0168-1591(99)00105-7
Collins MN, Friend TH, Jousan FD, Chen SC.Three groups of slaughter-type horses, totaling 30 mares and 29 geldings, were used to determine density effects on displacement (distance moved during a stop), falls, injuries, and orientation using a single-deck, open-topped commercial semi-trailer. Each horse was assigned to one of two treatments: high density (1.28 m(2)/horse with 14 horses) or low density (2.23 m(2)/horse with eight horses). Both treatments occurred sequentially on the same day (treatment order was alternated each trial), using the middle 2.44x7.32 m compartment of a large semi-tractor trailer. The horses were transported...
Differences in uterine position of reproductively normal mares and those with delayed uterine clearance detected by scintigraphy.
Theriogenology    March 29, 2000   Volume 50, Issue 1 49-54 doi: 10.1016/s0093-691x(98)00112-5
LeBlanc MM, Neuwirth L, Jones L, Cage C, Mauragis D.The position of the uterus within the abdomen may affect a mare's ability to rapidly clear the uterine lumen of contamination. In this study, the position of the uterus was determined from left and right lateral flank scintigrams taken 1 and 2 h after intrauterine infusion of radiocolloid. Scintigraphy was performed during estrus in 44 mares, 24 were reproductively normal and 20 exhibited a delay in uterine clearance. Reproductively normal mares were nulliparous (n = 14) or pluriparous (n = 10), 3 to 21 yr of age, had no history of persistent uterine infections and cleared > 50% of a radioc...
Gasterophilus nasalis infection: prevalence and pathological changes in equids in south-west England.
The Veterinary record    March 24, 2000   Volume 146, Issue 8 222-223 doi: 10.1136/vr.146.8.222
Coles GC, Pearson GR.No abstract available
Equestrian injuries: a five year review of hospital admissions in British Columbia, Canada.
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention    March 23, 2000   Volume 6, Issue 1 59-61 doi: 10.1136/ip.6.1.59
Sorli JM.To determine the demographics of hospital admissions and mortality associated with equestrian activities in the 33,000 riders in British Columbia (BC). Methods: Analysis of admission data from the Ministry of Health for the years 1991-96, review of information obtained from the Office of the Chief Coroner, and comparison of data from Canadian Hospitals Injury Reporting and Prevention Program. Results: The mean number of admissions per year was 390. Head injury was the most common cause of admission to hospital (20%) in BC. Females most often required admission (62%). Teenagers and children hav...