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Topic:Epidemiology

Epidemiology in horses involves the study of the distribution and determinants of health-related states and events in equine populations. It encompasses the investigation of patterns, causes, and effects of diseases and health conditions within horse populations. This field of study aims to identify risk factors for disease and targets for preventive healthcare. Key components of equine epidemiology include disease surveillance, outbreak investigation, and the study of disease dynamics within herds or regions. Research in this area often focuses on infectious diseases, zoonotic diseases, and the impact of environmental factors on equine health. This page compiles peer-reviewed research studies and scholarly articles that explore various aspects of epidemiology in horses, including disease prevalence, transmission pathways, and strategies for disease prevention and control.
Strains of Actinobacillus spp. from diseases of animals and ostriches in Zimbabwe.
The Onderstepoort journal of veterinary research    February 19, 1998   Volume 64, Issue 3 195-199 
Mohan K, Muvavarirwa P, Pawandiwa A.Among the Actinobacillus spp. only A. lignieresii represents a homogenous and well studied taxon. However, haemolytic and non-haemolytic strains of A. equuli and A. suis are also isolated from a wide range of diseases in a variety of hosts. These isolates often pose problems in definitive identification. Consequently, several studies have been published, emphasizing the need for detailed studies to reclassify various members of this genus and also to assess their disease significance. We isolated 48 strains of Actinobacillus from clinical cases in horses, cattle, sheep, cat, pigs and ostrich. ...
Association of deficiency in antibody response to vaccine and heterogeneity of Ehrlichia risticii strains with Potomac horse fever vaccine failure in horses.
Journal of clinical microbiology    February 18, 1998   Volume 36, Issue 2 506-512 doi: 10.1128/JCM.36.2.506-512.1998
Dutta SK, Vemulapalli R, Biswas B.Ehrlichia risticii is the causative agent of Potomac horse fever (PHF), which continues to be an important disease of horses. Commercial inactivated whole-cell vaccines are regularly used for immunization of horses against the disease. However, PHF is occurring in large numbers of horses in spite of vaccination. In a limited study, 43 confirmed cases of PHF occurred between the 1994 and 1996 seasons; of these, 38 (89%) were in horses that had been vaccinated for the respective season, thereby clearly indicating vaccine failure. A field study of horses vaccinated with two PHF vaccines indicated...
Biological control of gastro-intestinal nematodes–facts, future, or fiction?
Veterinary parasitology    February 14, 1998   Volume 72, Issue 3-4 479-492 doi: 10.1016/s0304-4017(97)00112-x
Larsen M, Nansen P, Grønvold J, Wolstrup J, Henriksen SA.The potential of using fungi to prevent nematodosis caused by parasites with free-living larval stages is well documented today. In this respect Duddingtonia flagrans, a net-trapping, nematode-destroying fungus, appears to be the most promising candidate. Laboratory experiments and in-vivo studies, where fungal spores have survived passage through the gastro-intestinal tract of cattle and horses, plus field studies with cattle, horses and pigs, demonstrate significant reduction in the number of infective larvae that develop in the faecal environment. In field trials this reduction subsequently...
Genetic variation of envelope gp90 gene of equine infectious anemia virus isolated from an experimentally infected horse.
The Journal of veterinary medical science    February 5, 1998   Volume 59, Issue 12 1089-1095 doi: 10.1292/jvms.59.1089
Pang H, Kong XG, Sentsui H, Kono Y, Sugiura T, Hasegawa A, Akashi H.Six strains of equine infectious anemia virus (EIAV) were recovered from febrile and non-febrile stages of a horse experimentally infected with the P337-V70 strain given once to a horse. The env gp90 genes of the isolates, the P337-V70 and P337-V26, avirulent virus derived from the P337-V70 strain, were sequenced. A comparison of the gp90 gene sequences revealed that amino acid variations among the viruses tested showed as high as 8.2 to 11.5%. In addition, the comparison also indicated that the isolates that recovered from the non-febrile stage were contained in nucleotide insertions in the p...
Venereal infection of mares by equine arteritis virus and use of killed vaccine against the infection.
Journal of comparative pathology    February 3, 1998   Volume 117, Issue 3 201-208 doi: 10.1016/s0021-9975(97)80015-1
Fukunaga Y, Wada R, Imagawa H, Kanemaru T.Venereal infection with equine arteritis virus (EAV) was established in each of seven mares by inoculation via the cervix with 20 ml of viral suspension (> or = 8 x 10(6) plaque-forming units; PFU), following treatment with prostaglandin and oestradiol. A dose of < or = 8 x 10(5) PFU produced infection in only five of eight mares. Serum neutralizing antibody developed in mares manifesting clinical signs of equine viral arteritis (EVA), and a weak antibody was detectable in one apparently healthy mare inoculated with 8 x 10(5) PFU. Virus isolation was demonstrated not only in the buffy coat but...
A novel P/V/C gene in a new member of the Paramyxoviridae family, which causes lethal infection in humans, horses, and other animals.
Journal of virology    January 28, 1998   Volume 72, Issue 2 1482-1490 doi: 10.1128/JVI.72.2.1482-1490.1998
Wang LF, Michalski WP, Yu M, Pritchard LI, Crameri G, Shiell B, Eaton BT.In 1994, a new member of the family Paramyxoviridae isolated from fatal cases of respiratory disease in horses and humans was shown to be distantly related to morbilliviruses and provisionally called equine morbillivirus (K. Murray et al., Science 268:94-97, 1995). To facilitate characterization and classification, the virus was purified, viral proteins were identified, and the P/V/C gene was cloned and sequenced. The coding strategy of the gene is similar to that of Sendai and measles viruses, members of the Paramyxovirus and Morbillivirus genera, respectively, in the subfamily Paramyxovirina...
An overview of pseudorabies (Aujeszky’s disease) and vesicular stomatitis from the Canadian Animal Health Network.
The Canadian veterinary journal = La revue veterinaire canadienne    January 27, 1998   Volume 39, Issue 1 23-32 
Inch C.No abstract available
Survival analysis of risk factors associated with the occurrence of lameness in a Michigan horse population.
American journal of veterinary research    January 27, 1998   Volume 59, Issue 1 23-29 
Ross WA, Kaneene JB, Gardiner JC.To evaluate the associations of operation and individual animal-level risk factors with occurrence of lameness in the Michigan horse population. Methods: 3,925 horses monitored from 138 randomly selected Michigan operations for a total of 814,753 horse-days. Methods: All horses monitored < 60 days were eliminated from the source population. From the remaining horses, a prospective unmatched case-control study population was generated that included all cases and a random sample of noncases. Analysis of risk factors associated with occurrence of lameness was conducted, using Cox's propor...
An outbreak of foal yersiniosis in Poland: pathological and bacteriological examination.
Zentralblatt fur Bakteriologie : international journal of medical microbiology    January 24, 1998   Volume 286, Issue 4 542-546 doi: 10.1016/s0934-8840(97)80058-8
Czernomysy-Furowicz D.In the springtime of 1995, 10 per cent of foals at a stud-farm died due to suppurative lesions. Three dead foals were examined. The manifestations of watery diarrhoea and pneumonia were observed. A profuse growth of an enterotoxigenic strain of Yersinia pseudotuberculosis was obtained from the internal organs of the foals. The foals with clinical symptoms of pneumonia and watery diarrhoea were immunized with Propionibacterium acnes t. II. All mares and their offspring from the stud were treated with an immunomodulator (Propionibacterium acnes t. II) and then vaccinated with a formalin-inactiva...
Comparison of nucleic and amino acid sequences and phylogenetic analysis of open reading frames 3 and 4 of various equine arteritis virus isolates.
Veterinary research    January 15, 1998   Volume 28, Issue 6 505-516 
Archambault D, Laganière G, Carman S, St-Laurent G.The genetic variation in equine arteritis virus (EAV) protein-encoding open reading frames (ORFs) 3 and 4 genes was investigated. Nucleic and deduced amino acid sequences from seven different EAV isolates (one European, one American and five Canadian isolates) and the Arvac vaccine strain were compared with those of Bucyrus reference strain. ORF 3 nucleotide and amino acid sequence identities between these isolates (including the Arvac vaccine strain) and the Bucyrus reference strain ranged from 85.6 to 98.8%, and 85.3 to 98.2%, respectively, whereas ORF 4 nucleotide and amino acid sequence id...
[Doping test for racehorses in Japan].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan    January 1, 1998   Volume 117, Issue 10-11 922-935 doi: 10.1248/yakushi1947.117.10-11_922
Uehara N, Momose A.The doping test method used in a horse race requires the accurate detection of a wide variety of drugs and metabolites as well as the rapidity in order to examine a large number of samples within a limited time. For this purpose, the routine method consists of a preliminary screening and a confirmatory test. In this paper, a historical review for the development of the doping test method in Japan is described. The metabolism and pharmacology of drugs in horses are also discussed.
What really causes colic in horses? Epidemiology’s role in elucidating the ultimate multi-factorial disease.
Equine veterinary journal    December 31, 1997   Volume 29, Issue 6 413-414 doi: 10.1111/j.2042-3306.1997.tb03150.x
Reeves MJ.No abstract available
Prospective study of equine colic risk factors.
Equine veterinary journal    December 31, 1997   Volume 29, Issue 6 454-458 doi: 10.1111/j.2042-3306.1997.tb03158.x
Tinker MK, White NA, Lessard P, Thatcher CD, Pelzer KD, Davis B, Carmel DK.A 1 year prospective study was conducted on 31 horse farms to identify risk factors for equine colic. Farms were randomly selected from a list from 2 adjacent counties of Virginia and Maryland, USA. The association between colic and farm or individual horse risk factors related to management, housing, pasture, use, nutrition, health and events was first examined by univariate statistical analysis. Individually significant (P < = 0.25 for farm factors, P < = 0.10 for horse factors) variables were used in a stepwise multivariable forward logistic regression to select explanatory factors (P < = 0...
Outbreak of Salmonella infantis infection in a large animal veterinary teaching hospital.
Journal of the American Veterinary Medical Association    December 31, 1997   Volume 211, Issue 12 1554-1557 
Tillotson K, Savage CJ, Salman MD, Gentry-Weeks CR, Rice D, Fedorka-Cray PJ, Hendrickson DA, Jones RL, Nelson W, Traub-Dargatz JL.During the past 11 years, there have been numerous reports of outbreaks of salmonellosis involving horses in veterinary teaching hospitals. Some of these outbreaks have been associated with Salmonella serotypes not commonly associated with infection of horses. Salmonella infantis is among the more common Salmonella serotypes isolated from human beings, and is an important pathogen in the broiler chicken industry. However, it was not commonly isolated from horses or cattle on a national basis between 1993 and 1995. In this report, we describe an outbreak of S infantis infection among large anim...
Isolation of Streptococcus equi subsp. equi from thoroughbred horses in a racehorse-breeding area of Japan.
The Journal of veterinary medical science    December 31, 1997   Volume 59, Issue 11 1031-1033 doi: 10.1292/jvms.59.1031
Anzai T, Nakanishi A, Wada R, Higuchi T, Hagiwara S, Takazawa M, Oobayashi K, Inoue T.For determination whether strangles has invaded the Hidaka district of Hokkaido, the main racehorse-breeding area of Japan, a epizootiological survey with bacterial isolation was carried out during the breeding season in 1995. Streptococcus equi subsp. equi, which is the causative agent of strangles, was isolated from two Thoroughbred horses with submandibular lymphadenitis. Isolates were identified by serological grouping, biochemical tests and analysis of cell surface proteins by Western immunoblotting. Through this survey, it revealed that S. equi subsp. equi has invaded the Hidaka district...
Characterisation of gamma herpesviruses in the horse by PCR.
Virology    December 31, 1997   Volume 238, Issue 1 8-13 doi: 10.1006/viro.1997.8825
Franchini M, Akens M, Bracher V, von Fellenberg R.A polymerase chain reaction (PCR) based on a combination of oligonucleotide primers selected using the octamer frequency disparity method with primers specific for EHV-5 (described by other authors) recognized all of a series of gamma herpesvirus field isolates. This PCR produced only three fragments: (1) one EHV-2-specific; (2) one EHV-5-specific; and (3) a fragment that occurred alone or in combination with the other two. Cloning and sequencing of four different isolates yielding only the last PCR product showed that this corresponds to a deletion/insertion mutant of EHV-2. The fact that thi...
Prospective study of equine colic incidence and mortality.
Equine veterinary journal    December 31, 1997   Volume 29, Issue 6 448-453 doi: 10.1111/j.2042-3306.1997.tb03157.x
Tinker MK, White NA, Lessard P, Thatcher CD, Pelzer KD, Davis B, Carmel DK.A prospective study of one year was conducted on 31 horse farms to obtain population based estimates of incidence, morbidity and mortality rates of equine colic. Farms with greater than 20 horses were enrolled by randomly selecting horse owners from 2 adjacent counties of Virginia and Maryland. Descriptive information for 1427 horses was collected at the initiation of the study and updated at 3 month intervals. Time on the farm during the study was tabulated for each horse. When colic was reported by the owner, investigators visited the farm to obtain information about the colic. The crude inc...
Equine headshaking survey.
The Veterinary record    December 24, 1997   Volume 141, Issue 19 504 
Mills D, Geering R.No abstract available
Effect of increasing the banking of a racetrack on the occurrence of injury and lameness in standardbred horses.
Australian veterinary journal    December 24, 1997   Volume 75, Issue 10 751-752 doi: 10.1111/j.1751-0813.1997.tb12261.x
Evans DL, Walsh JS.No abstract available
Antibodies against equine herpesviruses in free-ranging mountain zebras from Namibia.
Journal of wildlife diseases    December 10, 1997   Volume 33, Issue 4 812-817 doi: 10.7589/0090-3558-33.4.812
Borchers K, Frölich K.Twenty-one blood samples of free-ranging mountain zebras (Equus zebra) from Namibia were tested for equine herpesvirus (EHV-1, -2, -3, -4) specific antibodies by immunofluorescence assay (IFA) and neutralization test (NT). Additionally, type-specific nested polymerase chain reactions (nested PCR) were employed for detection of EHV-1, -2 and -4 DNA. Equine herpesvirus-1 antibodies were detected by IFA in all zebras, while only seven serum samples contained EHV-4 IFA antibodies. Sera with high IFA antibodies also were found to neutralize EHV-1 and -4. Furthermore, 20 zebras were EHV-2 seropositi...
Intrinsic, management, and nutritional factors associated with equine motor neuron disease.
Journal of the American Veterinary Medical Association    November 28, 1997   Volume 211, Issue 10 1261-1267 
de la Rúa-Domènech R, Mohammed HO, Cummings JF, Divers TJ, de Lahunta A, Summers BA.To identify intrinsic, management, nutritional, and environmental risk factors associated with equine motor neuron disease (EMND) and to determine whether epidemiologic evidence supports oxidative stress as a risk factor for developing EMND. Methods: Case-control study. Methods: 87 horses with EMND and 259 control horses. Methods: Information concerning each horse's history of exposure to multiple environmental factors prior to developing EMND was obtained by means of a questionnaire or personal interview. Exposure histories of horses with EMND and control horses were compared, and the associa...
Absence of Chlamydia as an aetiological factor in aborting mares.
The Veterinary record    November 19, 1997   Volume 141, Issue 16 424 doi: 10.1136/vr.141.16.424
Forster JL, Wittenbrink MM, Häni HJ, Corboz L, Pospischil A.No abstract available
Effect of different sampling techniques on odds ratio estimates using hospital-based cases and controls.
Preventive veterinary medicine    November 15, 1997   Volume 32, Issue 1-2 77-93 doi: 10.1016/s0167-5877(96)01146-4
Doherr MG, Carpenter TE, Wilson WD, Gardner IA.Potential biases introduced by the use of hospital admission records have rarely been discussed in the veterinary literature. Veterinary Medical Teaching Hospital (VMTH) patient records kept at the University of California, Davis (UCD) School of Veterinary Medicine provide a unique opportunity to perform in-depth analyses on the effect of different control selection (sampling) techniques on odds ratio (OR) estimates for disease risk factors in a retrospective case-control study. Horses with Corynebacterium pseudotuberculosis abscesses (134) and the (secondary) study base population (source for...
Nucleic acid amplification for rapid detection of Rhodococcus equi in equine blood and tracheal wash fluids.
American journal of veterinary research    November 15, 1997   Volume 58, Issue 11 1232-1237 
Sellon DC, Walker K, Suyemoto M, Altier C.To evaluate the ability of nucleic acid amplification techniques to detect Rhodococcus equi in equine buffy coat, blood, and tracheal wash fluid and to differentiate between virulent and avirulent strains of the bacteria. Methods: Blood anticoagulated with EDTA and tracheal wash fluid from healthy horses. Methods: Logarithmic dilutions of virulent and avirulent strains of R equi were added to equine buffy coat and tracheal wash fluid samples. The DNA was extracted and amplified by polymerase chain reaction (PCR), using primers specific for the 16S ribosomal subunit gene and the virulence plasm...
Genetic analysis of equine methicillin-resistant Staphylococcus aureus by pulsed-field gel electrophoresis.
The Journal of veterinary medical science    November 15, 1997   Volume 59, Issue 10 935-937 doi: 10.1292/jvms.59.935
Shimizu A, Kawano J, Yamamoto C, Kakutani O, Anzai T, Kamada M.Pulsed-field gel electrophoresis (PFGE) was used to determine genetic relationships among 15 methicillin-resistant Staphylococcus aureus (MRSA) isolates from mares with metritis and from a stallion with dermatitis in Hokkaido. All the 15 isolates showed phage pattern 6/47/54/75, coagulase type IV, and enterotoxin type A. The restriction endonuclease SmaI cut their genomic DNAs into 15 or 16 fragments ranging in size from 8 to 630 kb. Fourteen of the 15 isolates showed the same PFGE pattern, whereas the remaining one appeared to be closely related. The 9 human MRSA isolates showing the same phe...
Hemagglutination with equine arteritis virus.
The Journal of veterinary medical science    November 15, 1997   Volume 59, Issue 10 943-945 doi: 10.1292/jvms.59.943
Kubota T, Inaba Y, Uwatoko K, Akashi H, Fukunaga Y.Equine arteritis virus (EAV) grown on RK13 cell cultures was tested for hemagglutination (HA) with erythrocytes from a variety of species at 4 degrees C, room temperature and 37 degrees C. HA was observed at all temperatures with erythrocytes from mouse and chicken but not with those of cattle, horse, rabbit, guinea pig, mongolian gerbil, goose or chick embryo. Chickens showed an individual variation in agglutinability of their erythrocytes, requiring selection of birds to obtain erythrocytes for HA. The HA activity was enhanced by treatment of virus materials with Tween 80 followed by treatme...
Risk factors associated with musculoskeletal injuries in Australian thoroughbred racehorses.
Preventive veterinary medicine    November 15, 1997   Volume 32, Issue 1-2 47-55 doi: 10.1016/s0167-5877(97)00009-3
Bailey CJ, Reid SW, Hodgson DR, Suann CJ, Rose RJ.Risk factors for musculoskeletal injury in racing Thoroughbreds were investigated in a case-control study conducted at racetracks administered by the Australian Jockey Club. Univariable analysis of 137 cases from the official Veterinary Surgeon's reports and an equal number of randomly selected controls from the Australian Race Results identified field size, barrier position and class of race as being significantly associated with breakdown (P < 0.05). Multiple logistic regression was then used to investigate the effect of each putative risk factor whilst controlling for all others. Horses at ...
Risk factors associated with the likelihood of leptospiral seropositivity in horses in the state of New York.
American journal of veterinary research    November 5, 1997   Volume 58, Issue 10 1097-1103 
Barwick RS, Mohammed HO, McDonough PL, White ME.To determine and quantify risk factors associated with exposure of horses to the following serovars of Leptospira interrogans: pomona, autumnalis, and bratislava. Methods: 2,551 horses were randomly selected from a target population during the period of May 1991 to August 1993. Methods: Blood was collected from the horses and tested for antibodies to serovars, using the microscopic agglutination test. A titer > or = 1:100 indicated seropositivity. Information was collected on each horse, its environment, and each farm's management practices. Logistic regression analysis was used to develop a m...
Superficial digital flexor tendonitis in thoroughbred race horses: outcome following non-surgical treatment and superior check desmotomy.
Australian veterinary journal    November 5, 1997   Volume 75, Issue 9 631-635 doi: 10.1111/j.1751-0813.1997.tb15356.x
Gibson KT, Burbidge HM, Pfeiffer DU.This study documents the results of non-surgical treatment and treatment by superior check desmotomy in Thoroughbred racehorses with superficial digital flexor (SDF) tendonitis. Methods: A prospective study was made of 124 thoroughbred racehorses with unilateral or bilateral SDF tendonitis. Methods: The flexor tendons were assessed by physical and ultrasonographic examination before treatment, and the lesions detected in affected tendons were characterised according to lesion type, length and cross-sectional area. Ninety three horses were managed non-surgically and 31 by superior check desmoto...
Fatal and non-fatal farm injuries to children and adolescents in the United States, 1990-3.
Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention    October 27, 1997   Volume 3, Issue 3 190-194 doi: 10.1136/ip.3.3.190
Rivara FP.Examine the current magnitude of the injury problem to children and adolescents on farms, and to compare these data to that from 1978-83. Methods: US National Center for Health Statistics Mortality Multiple Cause of Death Tapes for the years 1991-3, and the US Consumer Product Safety Commission National Electronic Injury Surveillance System for data on emergency department visits for 1990-3. Methods: Children and adolescents 19 years and younger injured on farms. Results: There were an average of 104 deaths per year due to injuries occurring on farms. The rate of 8.0 deaths per 100,000 child f...