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Topic:Equine Diseases

Equine diseases encompass a wide range of health conditions that can affect horses, including infectious diseases, metabolic disorders, and genetic conditions. These diseases can impact the overall health, performance, and well-being of horses. Common equine diseases include equine influenza, equine herpesvirus, laminitis, and equine metabolic syndrome. Diagnosis and management of these diseases often require a combination of clinical evaluation, laboratory testing, and appropriate treatment strategies. This page gathers peer-reviewed research studies and scholarly articles that explore the etiology, pathophysiology, diagnosis, and treatment options for various equine diseases, providing valuable insights for veterinarians and researchers in the field.
Horse injuries and racing practices in National Hunt racehorses in the UK: the results of a prospective cohort study.
Veterinary journal (London, England : 1997)    November 19, 2003   Volume 167, Issue 1 45-52 doi: 10.1016/s1090-0233(03)00141-2
Pinchbeck GL, Clegg PD, Proudman CJ, Stirk A, Morgan KL, French NP.A prospective cohort study was conducted on horses starting in hurdle and steeplechase races on six UK racecourses in 2000 and 2001. Trainers or carers were questioned on the horses' pre-race routine and observational data were collected in the stables and parade ring. Some practices were common to many starters, such as withholding food and water before racing whereas other practices, such as schooling frequency, were more variable. There was a total of 2879 starts and a total of 83 injuries or medical events (28.8/1000 starts). The commonest types of injury were tendon/suspensory injuries an...
Assessment of the accuracy of computed tomography for measurement of normal equine pituitary glands.
American journal of veterinary research    November 19, 2003   Volume 64, Issue 11 1387-1394 doi: 10.2460/ajvr.2003.64.1387
McKlveen TL, Jones JC, Sponenberg DP, Scarratt K, Ward DL, Aardema CH.To describe the anatomic features of the pituitary gland region in horses via computed tomography (CT) and determine the accuracy of CT for estimating normal equine pituitary gland dimensions. Methods: 25 adult horses with no clinical signs of pituitary disease. Methods: Transverse CT images and gross transverse tissue sections were compared in 2 horses. Contrast-enhanced CT of the pituitary gland region was performed postmortem in 23 horses with 4 slice thickness and interval settings (10-mm contiguous or overlapping slices and 4-mm contiguous or overlapping slices). Gross and CT estimates of...
Retinal and optic nerve diseases.
Artificial organs    November 18, 2003   Volume 27, Issue 11 963-974 doi: 10.1046/j.1525-1594.2003.07304.x
Margalit E, Sadda SR.A variety of disease processes can affect the retina and/or the optic nerve, including vascular or ischemic disease, inflammatory or infectious disease, and degenerative disease. These disease processes may selectively damage certain parts of the retina or optic nerve, and the specific areas that are damaged may have implications for the design of potential therapeutic visual prosthetic devices. Outer retinal diseases include age-related macular degeneration, pathologic myopia, and retinitis pigmentosa. Although the retinal photoreceptors may be lost, the inner retina is relatively well-preser...
Laminitis in Przewalski horses kept in a semireserve.
Journal of veterinary science    November 14, 2003   Volume 2, Issue 1 1-7 
Budras KD, Scheibe K, Patan B, Streich WJ, Kim K.Semireserves were created by the European Conservation Project for scientific research in preparation for reintroduction in the wilderness. They are defined as enclosures large enough to carry a group of Przewalski horses throughout the year without any additional feeding. The semireserve offers diverse opportunities for significant scientific research. As part of a general screening program, the hoof development in a group of Przewalski horses was investigated in the semireserve Schorfheide near Berlin. Since the foundation of this semireserve in 1992, veterinary treatment was not necessary w...
Hormonal mechanism of follicle deviation as indicated by major versus minor follicular waves during the transition into the anovulatory season in mares.
Reproduction (Cambridge, England)    November 13, 2003   Volume 126, Issue 5 653-660 
Ginther OJ, Woods BG, Meira C, Beg MA, Bergfelt DR.Follicle growth and circulating hormone concentrations were compared between an interovulatory interval and the first 60 days of the anovulatory season in pony mares. Daily observations were made from November of three groups: (i) ablation of follicles of >/=6 mm in diameter at day 10 after an ovulation that initiated an interovulatory interval, as determined retrospectively (ovulatory group, n=8), (ii) ablation at day 10 after the last ovulation of the year (anovulatory-10 group, n=6); and (iii) ablation at day 60 after the last ovulation of the year (anovulatory-60 group, n=6). Follicular...
Methemoglobinemia and eccentrocytosis in equine erythrocyte flavin adenine dinucleotide deficiency.
Veterinary pathology    November 11, 2003   Volume 40, Issue 6 632-642 doi: 10.1354/vp.40-6-632
Harvey JW, Stockham SL, Scott MA, Johnson PJ, Donald JJ, Chandler CJ.This report describes erythrocyte biochemical findings in an adult Spanish mustang mare that exhibited persistent methemoglobinemia, eccentrocytosis, and pyknocytosis that were not related to the consumption or administration of an exogenous oxidant. The methemoglobinemia was attributed to a deficiency in cytochrome-b5 reductase (Cb5R) activity, and the eccentrocytes and pyknocytes were attributed to a marked deficiency in reduced nicotinamide adenine dinucleotide phosphate-dependent glutathione reductase (GR) activity that resulted in decreased reduced glutathione concentration within erythro...
Ex vivo magnetic resonance imaging of the distal row of equine carpal bones: assessment of bone sclerosis and cartilage damage. Anastasiou A, Skioldebrand E, Ekman S, Hall LD.The distal row of carpal bones (C2, C3, and C4) from eight left intercarpal joints--four from Standardbred Trotters and four from Swedish Warmblood horses--were used to assess the potential of magnetic resonance (MR) imaging to detect cartilage and bone lesions. The joints used in the study were classified by macroscopic and radiographic examinations as having normal, mild, moderate, or severe articular cartilage lesions and bone sclerosis. Those classifications correlated well with the appearance of the MR images. Bone sclerosis in the MR images was observed as regions of decreased signal int...
Preparation of equine isolated hepatocytes.
Toxicology in vitro : an international journal published in association with BIBRA    November 6, 2003   Volume 17, Issue 5-6 615-621 doi: 10.1016/s0887-2333(03)00112-7
Bakala A, Karlik W, Wiechetek M.In this study a detailed description of the equine hepatocyte isolation procedure is presented. Livers were obtained from horses slaughtered at the local slaughterhouse. For blood removal and liver preservation the following steps are suggested: perfusion with the oxygenated HBSS (0-2 degrees C, with continuous flow of 500-800 ml/min for 3-6 min), protection from ischemia injury by flushing with ice-cold University of Wisconsin Solution (UW, flow rate of 500-800 ml/min), and finally immersion of the liver lobe in UW solution (2 degrees C) during its transport to the laboratory. For equine isol...
Effects of acetylcysteine and migration of resident eosinophils in an in vitro model of mucosal injury and restitution in equine right dorsal colon.
American journal of veterinary research    November 5, 2003   Volume 64, Issue 10 1205-1212 doi: 10.2460/ajvr.2003.64.1205
Rötting AK, Freeman DE, Eurell JA, Constable PD, Wallig M.To evaluate the in vitro protective effects of acetylcysteine and response of resident mucosal eosinophils in oxidant-induced injury to tissues of right dorsal colon of horses. Methods: 9 adult horses. Methods: Gastrointestinal mucosa was damaged in vitro with 3 mM hypochlorous acid (HOCl), with and without prior exposure to 6mM acetylcysteine. Control tissues were not exposed to HOCl or acetylcysteine. Control and damaged tissues were incubated in Krebs-Ringer-bicarbonate solution and tissue resistance measured during 240 minutes. Tissue permeability to radiolabeled mannitol was also used to ...
Equine passports.
The Veterinary record    October 31, 2003   Volume 153, Issue 15 475 
Ellis RN.No abstract available
[The doping of racehorses].
Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology    October 30, 2003   Volume 16, Issue 3 315-321 
Ohtake I.No abstract available
Outbreak of equine herpesvirus type 1 myeloencephalitis: new insights from virus identification by PCR and the application of an EHV-1-specific antibody detection ELISA.
The Veterinary record    October 30, 2003   Volume 153, Issue 14 417-423 doi: 10.1136/vr.153.14.417
Studdert MJ, Hartley CA, Dynon K, Sandy JR, Slocombe RF, Charles JA, Milne ME, Clarke AF, El-Hage C.Five of 10 pregnant, lactating mares, each with a foal at foot, developed neurological disease. Three of them became recumbent, developed complications and were euthanased; of the two that survived, one aborted an equine herpesvirus type 1 (EHV-1)-positive fetus 68 days after the first signs were observed in the index case and the other gave birth to a healthy foal on day 283 but remained ataxic and incontinent. The diagnosis of EHV-1 myeloencephalitis was supported by postmortem findings, PCR identification of the virus and by serological tests with an EHV-1-specific ELISA. At the time of the...
Subpopulations of equine infectious anemia virus Rev coexist in vivo and differ in phenotype.
Journal of virology    October 29, 2003   Volume 77, Issue 22 12122-12131 doi: 10.1128/jvi.77.22.12122-12131.2003
Baccam P, Thompson RJ, Li Y, Sparks WO, Belshan M, Dorman KS, Wannemuehler Y, Oaks JL, Cornette JL, Carpenter S.Lentiviruses exist in vivo as a population of related, nonidentical genotypes, commonly referred to as quasispecies. The quasispecies structure is characteristic of complex adaptive systems and contributes to the high rate of evolution in lentiviruses that confounds efforts to develop effective vaccines and antiviral therapies. Here, we describe analyses of genetic data from longitudinal studies of genetic variation in a lentivirus regulatory protein, Rev, over the course of disease in ponies experimentally infected with equine infectious anemia virus. As observed with other lentivirus data, t...
Significance of affinity and cooperativity in oxygen binding to hemoglobin of horse fetal and maternal blood.
Zoological science    October 28, 2003   Volume 20, Issue 9 1087-1093 doi: 10.2108/zsj.20.1087
Zhang Y, Kobayashi K, Sasagawa K, Imai K, Kobayashi M.The physiological significance of the position and shape of the oxygen equilibrium curve (OEC) of horse hemoglobin (Hb) is considered from the viewpoint of oxygen (O2) transport efficiency and the effectiveness of the Bohr effect. In horse fetal and maternal bloods, their physiological O2 affinities are nearly optimized with respect to the effectiveness of the Bohr shift occurring at the O2 release site, when it is measured by the change in O2 saturation per unit change in P50. With relatively low cooperativity (n=2.69) of horse Hb under physiological conditions, the effectiveness of the Bohr ...
Radiographic imaging of the equine foot.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 379-vi doi: 10.1016/s0749-0739(03)00026-9
Redden RF.Radiographic examination of the equine foot can provide the veterinarian and farrier with a wealth of information. Positioning and selection of exposure factors are of central importance if one is to produce radiographs of maximum diagnostic value.
Form and function of the equine digit.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 285-v doi: 10.1016/s0749-0739(03)00018-x
Parks A.The list of possible diagnoses derived from matching anatomic structures or tissues to pathologic processes is inevitably broad in nature. Understanding and observation of distal limb function, conformation, and balance is the basis of identifying where the greatest abnormal stresses within the distal limb are likely to occur. This is key to focusing the diagnostic process and, in some instances, to treating the horse when a definitive diagnosis cannot be achieved.
Foot management in the foal and weanling.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 501-517 doi: 10.1016/s0749-0739(03)00016-6
Greet TR, Curtis SJ.Foot management and hoof care of foals, weanlings, and yearlings tends to be considered a specialist job. Many farriers and veterinary surgeons have little exposure to young and growing stock. Nevertheless, a variety of angular and flexural limb deformities can benefit from simple podiatry techniques, which can be performed provided that a few basic rules are followed. The combined skills of the farrier and veterinary surgeon offer many young horses with angular or flexural limb deformities a chance of a future athletic career.
Rabies DNA vaccine in the horse: strategies to improve serological responses.
Vaccine    October 25, 2003   Volume 21, Issue 31 4593-4596 doi: 10.1016/s0264-410x(03)00504-8
Fischer L, Minke J, Dufay N, Baudu P, Audonnet JC.In order for DNA vaccines to become a practical alternative to conventional vaccines their ability to induce antibody responses in large mammals needs to be improved. We used DNA vaccination against rabies in the horse as a model to test the potential of two different strategies to enhance antibody responses in a large mammalian species. The administration of the DNA vaccine in the presence of aluminum phosphate improved both the onset and the intensity of serological responses but was not potent enough to achieve seroconversion in all vaccinated ponies. However, when the DNA vaccine was formu...
Hoof wall defects: chronic hoof wall separations and hoof wall cracks.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 463-477 doi: 10.1016/s0749-0739(03)00003-8
Moyer W.Hoof wall defects in horses are common occurrences, and, fortunately, many of those detected present little or no danger to the individual horse. Those defects that are either presently a problem or have a great likelihood of being a problem do often require specialized consideration. Horse shoeing and farriery are ancient practices; over the years, a multitude of methods, theories, and management schemes have been proposed. It is unfortunate to note that few studies are available to provide an accurate incidence rate, a better understanding of the various causes, and, lastly, a comparative ap...
Diagnosis, treatment, and farriery for horses with chronic heel pain.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 417-441 doi: 10.1016/s0749-0739(03)00025-7
Dabareiner RM, Carter GK.In conclusion, horses with heel or navicular area pain vary, and no one treatment option is suitable for all horses. Each horse must be evaluated individually to determine which structure in the palmar aspect of the foot is injured, severity of disease, horse and hoof conformation, and horse use and level of performance expectation before a treatment plan can be developed. Overall, there are many treatment options to help these horses to perform their intended athletic event.
Chronic laminitis: current treatment strategies.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 393-vi doi: 10.1016/s0749-0739(03)00019-1
Parks A, O'Grady SE.Laminitis is divided into four different phases: developmental, acute, subacute, and chronic. The focus of this article is on treating the laminitic horse after the cessation of therapy for the acute phase, that is, usually 2 to 4 weeks after the onset of clinical signs.
Hoof capsule distortion: understanding the mechanisms as a basis for rational management.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 443-462 doi: 10.1016/s0749-0739(03)00027-0
Redden RF.Understanding the basic mechanisms of hoof capsule distortion enables the clinician to unravel the sometimes complex mix of abnormalities, identify early warning signs, and manage existing problems more effectively. Distortion of the hoof capsule can often seem like a complicated puzzle by the time the veterinarian is called to examine the lame horse. Evaluating each of the components of the hoof capsule, both individually and as an integrated unit, allows the clinician to tease apart the tangle of primary and secondary problems and come up with effective options for countering or attenuating ...
Hoof repair and glue-on shoe adhesive technology.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 519-530 doi: 10.1016/s0749-0739(03)00021-x
Cheramie HS, O'Ggrady SE.There are many different commercially available hoof repair/adhesive products. The application of these products in the treatment of various foot conditions is continuing to evolve based on sound medical and farriery principles as well as imagination. Successful application of these products depends largely on using proper hoof wall preparation and adhesive application techniques. Success also depends on a realistic expectation of the final outcome when accounting for the physical limitations of the adhesive products and the underlying hoof problem. Our results with these techniques have been ...
The role and importance of farriery in equine veterinary practice.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 273-283 doi: 10.1016/s0749-0739(03)00022-1
Merriam JG.There is a lot of room for us to become the central source of medical information regarding shoeing and lameness in our own practice area. This takes a good bit of effort and a real "outreach" to client and farrier. It can be done with the one tool we are best at--the acquisition and careful dispensing of information that we can put together regarding the health of the foot. Such information includes the following: 1. Radiographically guided hoof trimming and shoeing. 2. Ultrasonography. 3. Digital radiography. 4. Thermography. 5. Nutritional and health counseling. Become the "local" expert in...
Examination of the equine foot.
The Veterinary clinics of North America. Equine practice    October 25, 2003   Volume 19, Issue 2 309-332 doi: 10.1016/s0749-0739(03)00023-3
Turner TA.The examination of the foot must be based on observations of the hoof, followed by a careful determination of areas of pain. This must be followed by an assessment of the biomechanical forces on the hoof and limb. Finally, imaging gives insight into the nature of the injury and allows the examiner to prognosticate the outcome.
Horses added to the list of cloned species.
Reproductive biomedicine online    October 22, 2003   Volume 7, Issue 2 138 
No abstract available
Clinical and pathologic findings in two draft horses with progressive muscle atrophy, neuromuscular weakness, and abnormal gait characteristic of shivers syndrome.
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1661-1621 
Valentine BA, de Lahunta A, Divers TJ, Ducharme NG, Orcutt RS.Two Belgian geldings, 4 and 14 years old, respectively, with muscle atrophy, weakness, and abnormal gait characteristic of severe advanced shivers were examined clinically and on necropsy. Neurologic examination revealed no evidence of ataxia, and the clinical diagnosis was neuromuscular weakness and shivers. Necropsies of both horses, including examination of pituitary, brain, spinal cord, spinal roots and ganglia, and peripheral nerves, revealed no gross or histologic abnormalities. Examination of multiple skeletal muscle specimens revealed chronic myopathic changes and periodic acid-Schiff ...
Questions effect of furosemide on racing Thoroughbreds.
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1580-1581 
Lundin CS.No abstract available
Healing characteristics of deep digital flexor tenorrhaphy within the digital sheath of horses.
Veterinary surgery : VS    October 22, 2003   Volume 32, Issue 5 421-430 doi: 10.1053/jvet.2003.50059
Jann H, Blaik M, Emerson R, Tomioka M, Stein L, Moll D.To describe the healing characteristics of deep digital flexor tenorrhaphy within the digital sheath. Methods: Experimental study. Methods: Five mature horses. Methods: Right thoracic limb, deep digital flexor tenorrhaphy was performed within the digital sheath. Limbs were cast in partial flexion using a short limb cast for 6 weeks. Next, extended heel shoes were used for limb support for 14 weeks. Healing was evaluated by sequential ultrasonographic examinations, and limb use was evaluated by force plate analysis. At 26 weeks, mechanical strength and morphologic characteristics of the repair ...
Empyema of the guttural pouch (auditory tube diverticulum) in horses: 91 cases (1977-1997).
Journal of the American Veterinary Medical Association    October 22, 2003   Volume 215, Issue 11 1666-1670 
Judy CE, Chaffin MK, Cohen ND.To identify features of guttural pouch (auditory tube diverticulum) empyema in horses and compare findings of uncomplicated guttural pouch empyema with guttural pouch empyema complicated by chondroids. Methods: Retrospective study. Methods: 91 horses with guttural pouch empyema. Methods: Medical records of horses with guttural pouch empyema were reviewed. Results: The most common owner complaint and abnormal finding was persistent nasal discharge. Chondroids were detected in 21% (19/91) of affected horses. Streptococcus equi was isolated from the guttural pouch in 14 of 44 horses; for Streptoc...