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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Advanced fertility diagnosis in stallion semen using transmission electron microscopy.
Animal reproduction science    May 31, 2005   Volume 91, Issue 3-4 285-298 doi: 10.1016/j.anireprosci.2005.04.004
Pesch S, Bostedt H, Failing K, Bergmann M.Routine semen analysis of stallions is based on light microscopy (LM). However, there are still a number of animals that are subfertile or even infertile not being identified with conventional semen analysis. The objective of this study was to investigate the suitability of transmission electron microscopy (TEM) for advanced fertility diagnosis in stallion. We examined ejaculates of 46 stallions with known fertility. Animals were divided into three different groups: group 1, fertile stallions (pregnant mares> or =70%, n=29); group 2, subfertile stallions (pregnant mares 10-69%, n=14); group 3,...
Airway inflammation is associated with mucous cell metaplasia and increased intraepithelial stored mucosubstances in horses.
Veterinary journal (London, England : 1997)    May 31, 2005   Volume 172, Issue 2 293-301 doi: 10.1016/j.tvjl.2005.04.018
Lugo J, Harkema JR, deFeijter-Rupp H, Bartner L, Boruta D, Robinson NE.This study was performed to determine if a peripheral sample of lung from the site where biopsy is conducted is representative of the rest of the lung and to investigate the relationship between airway inflammation and intraepithelial mucous production in the peripheral airways. Lung parenchyma samples were collected from five different regions of the lung in five control and five heaves-affected horses. Horse groups were defined by clinical response to stabling. Tissue sections were used for semi-quantitative scoring of lesions, to count the number of airways, to quantify the amount of stored...
The pharmacokinetics of hemoglobin-based oxygen carrier hemoglobin glutamer-200 bovine in the horse.
Anesthesia and analgesia    May 28, 2005   Volume 100, Issue 6 1570-1575 doi: 10.1213/01.ANE.0000154081.38466.09
Soma LR, Uboh CE, Guan F, Luo Y, Moate PJ, Boston RC, Driessen B.Hemoglobin-glutamer-200 (HBOC-200) is a hemoglobin (Hb)-based oxygen carrier (HBOC) comprising glutaraldehyde-polymerized bovine Hb. In this study, we sought to determine the pharmacokinetics of this first generation HBOC after IV infusion of 32.5 g of HBOC-200 solution in horses. Quantification of HBOC-200 in equine plasma and urine was performed using a method recently developed by our laboratory. The elimination from plasma was based on size distribution of the bovine Hb polymer. The decline of plasma concentration-time curve of HBOC-200 was described by a noninterchanging 2-compartmental m...
Equine interferon gamma synthesis in lymphocytes after in vivo infection and in vitro stimulation with EHV-1.
Vaccine    May 26, 2005   Volume 23, Issue 36 4541-4551 doi: 10.1016/j.vaccine.2005.03.048
Paillot R, Daly JM, Juillard V, Minke JM, Hannant D, Kydd JH.Equine cytotoxic T lymphocyte (CTL) responses to equine herpesvirus-1 (EHV-1) are well characterised but little is known about the cytokine response after infection or vaccination. EHV-1 is common in horses and infects lymphocytes in vivo. This virus was used as a model to measure the synthesis of interferon gamma (IFN-gamma) by equine peripheral blood mononuclear cells (PBMC) after in vivo infection and/or in vitro stimulation with EHV-1. Both flow cytometry and ELISPOT assays were used to quantify equine IFN-gamma using a mouse anti-bovine IFN-gamma monoclonal antibody (clone CC302; shown to...
Left ventricular size and systolic function in Thoroughbred racehorses and their relationships to race performance.
Journal of applied physiology (Bethesda, Md. : 1985)    May 26, 2005   Volume 99, Issue 4 1278-1285 doi: 10.1152/japplphysiol.01319.2004
Young LE, Rogers K, Wood JL.Cardiac morphology in human athletes is known to differ, depending on the sports-specific endurance component of their events, whereas anecdotes abound about superlative athletes with large hearts. As the heart determines stroke volume and maximum O(2) uptake in mammals, we undertook a study to test the hypothesis that the morphology of the equine heart would differ between trained horses, depending on race type, and that left ventricular size would be greatest in elite performers. Echocardiography was performed in 482 race-fit Thoroughbreds engaged in either flat (1,000-2,500 m) or jump racin...
Equine herpesviruses 1 and 4: creeping to a solution.
Veterinary journal (London, England : 1997)    May 26, 2005   Volume 170, Issue 1 6-7 doi: 10.1016/j.tvjl.2004.07.001
Smith K.No abstract available
Effect of seminal plasma on the cryopreservation of equine spermatozoa.
Theriogenology    May 25, 2005   Volume 63, Issue 9 2372-2381 doi: 10.1016/j.theriogenology.2004.05.032
Moore AI, Squires EL, Graham JK.Seminal plasma is generally removed from equine spermatozoa prior to cryopreservation. Two experiments were designed to determine if adding seminal plasma back to spermatozoa, prior to cryopreservation, would benefit the spermatozoa. Experiment 1 determined if different concentrations of seminal plasma affected post-thaw sperm motility, viability and acrosomal integrity of frozen/thawed stallion spermatozoa. Semen was washed through 15% Percoll to remove seminal plasma and spermatozoa resuspended to 350 x 10(6)sperm/mL in a clear Hepes buffered diluent containing either 0, 5, 10, 20, 40 or 80%...
Effect of vaccination against leptospirosis on the frequency, days to recurrence and progression of disease in horses with equine recurrent uveitis.
Veterinary ophthalmology    May 25, 2005   Volume 8, Issue 3 171-179 doi: 10.1111/j.1463-5224.2005.00367.x
Rohrbach BW, Ward DA, Hendrix DV, Cawrse-Foss M, Moyers TD.To evaluate the effect of vaccination against leptospirosis on frequency and days to recurrence of uveitis and progression of disease in horses with equine recurrent uveitis (ERU). Methods: Forty-one horses with ERU. Methods: Horses were randomly assigned to experimental (vaccinated) or control groups. Vaccine containing six serovars of Leptospira or placebo was administered, an ophthalmic examination performed and blood samples drawn on days 0, 28, 180 and 365. Antibody titers were measured against each serovar. Recurrence of uveitis was verified by ophthalmic examination. Results of the init...
Primary invasive ocular squamous cell carcinoma in a horse.
Veterinary ophthalmology    May 25, 2005   Volume 8, Issue 3 193-197 doi: 10.1111/j.1463-5224.2005.00358.x
Kaps S, Richter M, Philipp M, Bart M, Eule C, Spiess BM.A 12-year-old Haflinger gelding was presented to the veterinary medical teaching hospital of the University of Zurich with a light-pink raised mass on the temporal limbus and conjunctiva of the left eye. Squamous cell carcinoma was confirmed histologically after keratectomy and cryotherapy. Seven months later, a smooth pink, progressively enlarging mass was observed within the cornea of the left eye. Ultrasonographically, the mass was not only infiltrating the corneal stroma but seemed to protrude into the anterior chamber. The globe was surgically removed and submitted for pathology. A histol...
Effect of alpha-tocopherol and tocopherol succinate on lipid peroxidation in equine spermatozoa.
Animal reproduction science    May 25, 2005   Volume 87, Issue 3-4 321-337 doi: 10.1016/j.anireprosci.2004.12.004
Almeida J, Ball BA.The objective of this study was to compare the effect of alpha-tocopherol and its ester, alpha tocopherol succinate, on lipid peroxidation and motility of equine spermatozoa. In experiment one, spermatozoa were incubated with dl-alpha-tocopherol (5, 25, 100 or 500 microM), DL-alpha tocopherol succinate (5, 25, 100 or 500 microM) or vehicle (0.5% ethanol) at 38 degrees C, and sperm motility was determined at 30, 60 and 120 min. In experiment two, spermatozoa loaded with the lipophilic probe, C11BODIPY(581/591), were incubated with dl-alpha-tocopherol (50 and 100 microM), DL-alpha-tocopherol suc...
Tear urea nitrogen and creatinine levels in horse and their correlation with serum values.
Veterinary ophthalmology    May 25, 2005   Volume 8, Issue 3 207-209 doi: 10.1111/j.1463-5224.2005.00392.x
Zapata GL, Britos RM, Pintos ME, Dreizzen E, Lausada NB, Arauz S.The objective of this paper was to determine the physiological values of urea nitrogen and creatinine in tears, and to compare the results with those obtained from serum. Thirty healthy thoroughbred horses were included in the study. Tear fluid samples were obtained using a glass capillary tube placed in lower conjunctival cul-de-sac. Blood samples were taken from the jugular vein. Tear and serum urea nitrogen and creatinine levels were quantitatively analyzed by an enzymatic colorimetric method. Urea nitrogen values were 4.22+/-1.84 mmol/l in tears and 4.44+/-1.78 mmol/l in serum, whereas cre...
Modulation of equine articular chondrocyte messenger RNA levels following brief exposures to recombinant equine interleukin-1beta.
Veterinary immunology and immunopathology    May 25, 2005   Volume 106, Issue 1-2 23-38 doi: 10.1016/j.vetimm.2005.01.003
Takafuji VA, Howard RD, Ward DL, Sharova LV, Crisman MV.The effect of recombinant equine IL-1beta (EqIL-1beta) on steady-state mRNA levels of equine articular chondrocytes in high-density monolayer culture was investigated using a customized cDNA array analysis. Total RNA samples isolated from chondrocytes cultured in media alone or with the addition of 1 ng/ml EqIL-1beta for 1-, 3-, and 6-h durations of exposure were reverse transcribed, radiolabeled, and hybridized to a customized 380-target cDNA array. Means of duplicate log base 2 transformed hybridization signals were normalized to equine glyceraldehyde 3-phosphate dehydrogenase (GAPDH) mean s...
Effect of prolonged use of altrenogest on behaviour in mares.
Veterinary journal (London, England : 1997)    May 25, 2005   Volume 169, Issue 3 322-325 doi: 10.1016/j.tvjl.2005.03.003
Hodgson D, Howe S, Jeffcott L, Reid S, Mellor D, Higgins A.Oral administration of altrenogest for oestrus suppression in competition horses is believed to be widespread in some equestrian disciplines, and can be administered continuously for several months during a competition season. To examine whether altrenogest has any anabolic or other potential performance enhancing properties that may give a horse an unfair advantage, we examined the effect of oral altrenogest (0.044 mg/kg), given daily for a period of eight weeks, on social hierarchy, activity budget, body-mass and body condition score of 12 sedentary mares. It was concluded that prolonged ora...
Evaluation of the clinical efficacy of prokinetic drugs in the management of post-operative ileus: can retrospective data help us?
Veterinary journal (London, England : 1997)    May 24, 2005   Volume 170, Issue 2 230-236 doi: 10.1016/j.tvjl.2004.06.006
Smith MA, Edwards GB, Dallap BL, Cripps PJ, Proudman CJ.The objectives of the study were to determine whether retrospective data can be used to answer questions about the efficacy of prokinetic agents when used to treat horses with post-operative ileus (POI). We describe prevalence and mortality of POI with reference to treatment with four prokinetic agents. By combining data from two Hospitals a study population of 55 horses with POI following pedunculated lipoma obstruction (PLO) was established. Univariable and multivariable associations were determined between short term survival and potential explanatory variables. With death as outcome in mul...
[Additional information on the article amitraz intoxications in the horse].
Tijdschrift voor diergeneeskunde    May 24, 2005   Volume 130, Issue 9 288 
Westermann CM.No abstract available
Third metacarpal bone laterality asymmetry and midshaft dimensions in Thoroughbred racehorses.
Australian veterinary journal    May 24, 2005   Volume 83, Issue 4 224-226 doi: 10.1111/j.1751-0813.2005.tb11657.x
Davies HM, Watson KM.The aims of this study were to test whether longer third metacarpal (MC3) bones had thicker dorsal cortices in a group of racehorses that were exercising at similar maximum speeds, and to establish if horses with larger differences in length between their right and left MC3 bones showed larger differences in the dorsal cortical thickness between the two limbs. Methods: An observational study. Methods: Forty Thoroughbred racehorses aged between 2 and 6 years and in training at racing speed at two racing stables were used. Two sets of radiographs of each left and right metacarpus of each horse w...
In vitro comparisons of two cryopreservation techniques for equine embryos: slow-cooling and open pulled straw (OPS) vitrification.
Theriogenology    May 24, 2005   Volume 64, Issue 7 1619-1632 doi: 10.1016/j.theriogenology.2005.04.001
Moussa M, Bersinger I, Doligez P, Guignot F, Duchamp G, Vidament M, Mermillod P, Bruyas JF.Vitrification using open pulled straw (OPS) has provided encouraging results with embryos from other species. The aim of this study was to compare the survival of 6.5- and 6.75-day-old equine embryos after OPS vitrification and slow-cooling. Eighteen embryos were frozen using a slow-cooling method. Embryos were placed in modified PBS with increasing glycerol concentration (2.5%, 5%, 7.5% and 10% (v/v) 5 min each). Embryos were loaded into 0.25 ml straws then placed in a programmable freezer and subsequently plunged into liquid nitrogen. After thawing, cryoprotectant was removed by five steps w...
Lameness and poor performance in horses used for team roping: 118 cases (2000-2003).
Journal of the American Veterinary Medical Association    May 24, 2005   Volume 226, Issue 10 1694-1699 doi: 10.2460/javma.2005.226.1694
Dabareiner RM, Cohen ND, Carter GK, Nunn S, Moyer W.To determine the types of musculoskeletal problems that result in lameness or poor performance in horses used for team roping and determine whether these problems are different in horses used for heading versus heeling. Methods: Retrospective study. Methods: 118 horses. Methods: Medical records of team roping horses that were evaluated because of lameness or poor performance were reviewed to obtain information regarding signalment, primary use (ie, head horse or heel horse), history, results of physical and lameness examinations, diagnostic tests performed, final diagnosis, and treatment. Resu...
Theriogenology question of the month. Seminoma, spermatocele, sustentacular cell tumor.
Journal of the American Veterinary Medical Association    May 24, 2005   Volume 226, Issue 10 1649-1650 doi: 10.2460/javma.2005.226.1649
Threlfall WR, Robertson JT, Munsterman AS, Oglesbee MJ, Hubbell JA.No abstract available
Up-regulation of site-specific remodeling without accumulation of microcracking and loss of osteocytes.
Bone    May 24, 2005   Volume 37, Issue 1 16-24 doi: 10.1016/j.bone.2004.12.016
Da Costa Gómez TM, Barrett JG, Sample SJ, Radtke CL, Kalscheur VL, Lu Y, Markel MD, Santschi EM, Scollay MC, Muir P.Functional adaptation of bone normally protects the skeleton from fracture during daily activity. Accumulation of microcracking and loss of osteocytes have been implicated in the regulation and initiation of targeted (reparative) remodeling of bone and, in certain situations, the development of fatigue or stress fracture. We performed a histologic study of the dorsal cortex of the mid-diaphysis of the third metacarpal (Mc-III) bone of Thoroughbred racehorses after bones were bulk-stained in basic fuchsin and transverse calcified sections were prepared. The Thoroughbred racehorse is an extreme ...
Conservative treatment of intra-articular distal phalanx fractures in horses not used for racing.
Australian veterinary journal    May 24, 2005   Volume 83, Issue 4 221-223 doi: 10.1111/j.1751-0813.2005.tb11656.x
Ohlsson J, Jansson N.To determine the success rate and whether specific patient and treatment factors influenced the outcome after conservative treatment with a bar shoe with quarter clips of intra-articular fractures of the distal phalanx in horses not used for racing. Methods: Retrospective study. Methods: Thirty-two client-owned horses. Methods: Hospital records of horses that had been treated conservatively for intra-articular fractures of the distal phalanx at Skara Equine Hospital or Halland Animal Hospital in Sweden between 1995 and 2001 were reviewed. Racehorses in active training and horses affected with ...
Significance of Cryptosporidium parvum in horses.
The Veterinary record    May 24, 2005   Volume 156, Issue 21 688 doi: 10.1136/vr.156.21.688
Chalmers RM, Grinberg A.No abstract available
Transcervical endoscope-guided emptying of a transmural uterine cyst in a mare.
The Veterinary record    May 24, 2005   Volume 156, Issue 21 679-682 doi: 10.1136/vr.156.21.679
Rambags BP, Stout TA.An 18-year-old Friesian mare with a large intrauterine cyst was examined by transrectal ultrasonography. There were several small to moderately sized intraluminal endometrial cysts, one of which connected via the myometrium to a large subserosal cyst, thereby effectively forming a 'transmural' cyst complex. During a videohysteroscopy, the intraluminal part of this transmural cyst was removed by electrocoagulation via a polypectomy snare. It was then possible to drain the large subserosal part of the cyst into the uterine lumen by transrectal massage, thereby confirming the presence of the tran...
Efficacy of omeprazole paste for prevention of recurrence of gastric ulcers in horses in race training.
Journal of the American Veterinary Medical Association    May 24, 2005   Volume 226, Issue 10 1685-1688 doi: 10.2460/javma.2005.226.1685
McClure SR, White GW, Sifferman RL, Bernard W, Hughes FE, Holste JE, Fleishman C, Alva R, Cramer LG.To determine whether omeprazole oral paste administered at a dosage of 0.5 or 1 mg/kg (0.23 or 0.45 mg/lb), PO, every 24 hours would effectively prevent the recurrence of gastric ulcers in horses in race training. Methods: Prospective study. Methods: 135 horses. Methods: Horses with gastric ulcers were treated with omeprazole at a dosage of 4 mg/kg (1.8 mg/lb), PO, every 24 hours for 28 days. Horses in the dose selection portion of the study were sham dose treated or received 0.5 or 1 mg of omeprazole/kg, PO, every 24 hours for an additional 28 days. Horses in the dose confirmation portion of ...
Equine hemi-castration: review of the condition, prevalence, aetiology, diagnosis and surgical management.
Australian veterinary journal    May 24, 2005   Volume 83, Issue 4 203-207 doi: 10.1111/j.1751-0813.2005.tb11648.x
Maxwell JA.No abstract available
Intravenous amiodarone treatment in horses with chronic atrial fibrillation.
Veterinary journal (London, England : 1997)    May 24, 2005   Volume 172, Issue 1 129-134 doi: 10.1016/j.tvjl.2005.04.001
De Clercq D, van Loon G, Baert K, Tavernier R, Croubels S, De Backer P, Deprez P.Six horses without underlying cardiac disease were presented because of atrial fibrillation of between 5 and 12 months duration. These horses received an intravenous amiodarone treatment of 5mg/kg/h for 1 h followed by 0.83mg/kg/h for 23h and subsequently 1.9mg/kg/h for 30h. During treatment, clinical signs were monitored and a surface ECG and an intra-atrial electrogram were recorded. Infusion was discontinued when sinus rhythm or side effects occurred. Four horses successfully cardioverted, of which one showed symptoms of hind limb weakness and weight shifting. Two horses did not cardiovert ...
Behavioral responses to two intranasal vaccine applicators in horses and ponies.
Journal of the American Veterinary Medical Association    May 24, 2005   Volume 226, Issue 10 1689-1693 doi: 10.2460/javma.2005.226.1689
Grogan EH, McDonnell SM.To evaluate behavioral compliance of horses and ponies with simulated intranasal vaccination and assess development of generalized aversion to veterinary manipulations. Methods: Clinical trial. Methods: 28 light horse mares, 3 pony geldings, 2 light horse stallions, and 3 pony stallions that had a history of compliance with veterinary procedures. Methods: Behavioral compliance with 2 intranasal vaccine applicators was assessed. Compliance with standard physical examination procedures was assessed before and after a single experience with either of the applicators or a control manipulation to e...
Comparison of cell proliferation index in equine and caprine embryos using a modified BrdU incorporation assay.
Theriogenology    May 24, 2005   Volume 64, Issue 8 1823-1832 doi: 10.1016/j.theriogenology.2005.04.016
The measurement of cell proliferation and cell viability using 5'bromo-2'deoxy-uridine (BrdU) labelling has been described in several cell types and species. The aim of this study was to adapt this technique to equine embryos and to compare the index of DNA replication (S-phase) between equine and caprine embryos. Seventeen equine embryos were recovered at day 6.5 post-ovulation and 20 caprine embryos were recovered at day 7 after the onset of estrus. Equine embryos were incubated during 1h at 39 degrees C in PBS containing 1mM of BrdU. Embryos were then treated in 0.05% trypsin during 15 min ...
Assignment of the equine colony stimulating factor 1 receptor gene (CSF1R) to equine chromosome 14q15–>q16 (ECA14q15–>q16) by in situ hybridization and radiation hybrid panel mapping.
Cytogenetic and genome research    May 24, 2005   Volume 109, Issue 4 533 doi: 10.1159/000084221
Beck J, Chowdhary BP, Brenig B.No abstract available
Epidemiological studies on equine cestodes in central Spain: infection pattern and population dynamics.
Veterinary parasitology    May 24, 2005   Volume 130, Issue 3-4 233-240 doi: 10.1016/j.vetpar.2005.03.040
Meana A, Pato NF, Martín R, Mateos A, Pérez-García J, Luzón M.An epidemiological study on equine cestodosis was carried out in central Spain. A total of 372 digestive tracts from equids slaughtered in abattoirs located in central Spain were studied from November 2001 to May 2004. Anoplocephala perfoliata was detected in 24% of the animals and Anoplocephala magna in 18%. Individual tapeworm burden was from 1 to 491 tapeworms for A. perfoliata and from 1 to 64 tapeworms for A. magna. Low tapeworm burdens (less than 30 cestodes) predominated significantly (p<0.01) in all seasons for both species. Seasonal prevalence of infection by A. perfoliata was signifi...