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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Antioxidant and inflammatory responses of healthy horses and horses affected by recurrent airway obstruction to inhaled ozone.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 243-249 doi: 10.2746/0425164054530605
Deaton CM, Marlin DJ, Smith NC, Roberts CA, Harris PA, Schroter RC, Kelly FJ.Inhaled ozone can induce oxidative injury and airway inflammation. Horses affected by recurrent airway obstruction (RAO) have a decreased pulmonary antioxidant capacity, which may render them more susceptible to oxidative challenge. It is currently unknown whether RAO-affected horses are more susceptible to oxidative stress than those unaffected by RAO. Objective: To determine whether ozone exposure induces greater oxidative stress and airway inflammation in RAO-affected horses in remission than in healthy horses. Methods: Seven healthy control horses and 7 RAO-affected horses were exposed to ...
A novel, progressive, sclerosing panencephalitis in a horse.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 276-280 doi: 10.2746/0425164054530623
Swain JM, Hudson NP, Rhind SM, Baird PM, Mayhew IG.No abstract available
Demonstration of regional differences in equine ventricular myocardial velocity in normal 2-year-old Thoroughbreds with Doppler tissue imaging.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 222-226 doi: 10.2746/0425164054530722
Sepulveda MF, Perkins JD, Bowen IM, Marr CM.Doppler tissue imaging (DTI) is a novel noninvasive method by which myocardial velocity can be assessed directly and it allows regional, rather than global, cardiac function to be evaluated. Objective: That regional differences in myocardial velocities exist within the equine ventricle. Objective: To develop a repeatable examination technique for DTI in horses, describe DTI findings in various regions of the normal equine ventricle, compare colour (CDTI) and spectral (SDTI) techniques of DTI, and document regional differences in myocardial velocity. Methods: Five regions of the ventricles (rig...
Endothelial mechanisms underlying responses to acetylcholine in the horse deep dorsal penile vein.
European journal of pharmacology    May 17, 2005   Volume 515, Issue 1-3 150-159 doi: 10.1016/j.ejphar.2005.04.012
Martínez AC, Prieto D, Hernández M, Rivera L, Recio P, García-Sacristán A, Benedito S.This study evaluates the mechanisms underlying endothelium-dependent responses to acetylcholine in horse deep dorsal penile veins. Acetylcholine-induced relaxation was abolished by endothelium removal, the soluble guanylyl cyclase-inhibitor, and the nitric oxide (NO) synthase inhibitors. Acetylcholine-induced relaxation was inhibited by high K+ concentrations and blockade of large-conductance Ca(2+)-activated potassium (BK(Ca)) channels, and voltage-dependent potassium (K(v)) channels. Relaxations were unaffected by a small-conductance K(Ca) (SK(Ca)) channel blocker, or an ATP-sensitive potass...
Bacterial isolates and antimicrobial susceptibilities in equine bacterial ulcerative keratitis (1993–2004).
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 207-211 doi: 10.2746/0425164054530731
Keller RL, Hendrix DV.Bacterial ulcerative keratitis is a common and often vision-threatening problem in horses. Emerging bacterial resistance to commonly used topical antibiotics has been demonstrated. Previous antibiotic use may alter the antimicrobial susceptibility of bacterial isolates. Objective: To document aerobic bacterial isolates and associated bacterial susceptibilities from horses with ulcerative keratitis treated at the University of Tennessee between January 1993 and May 2004 and determine whether prior antibiotic therapy affected antimicrobial susceptibility of the isolates. Methods: Medical records...
Sudden death in racing Thoroughbreds in Victoria, Australia.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 269-271 doi: 10.2746/0425164054530597
Boden LA, Charles JA, Slocombe RF, Sandy JR, Finnin PJ, Morton JM, Clarke AF.Racing fatalities are an important welfare concern and a source of economic loss to racing industries. A fatality can be categorised as sudden (a death occurring while racing/training or within minutes of finishing) or as a euthanasia if a horse is destroyed after incurring a catastrophic injury while racing or training. Sudden deaths of racehorses have been attributed to respiratory and cardiovascular disease (Platt 1982; Gelberg et al. 1985; Gunson et al. 1988; Johnson et al. 1994a,b). Respiratory causes of sudden death include exercise-induced pulmonary haemorrhage (EIPH) and pre-e...
Masseter myodegeneration as a cause of trismus or dysphagia in adult horses.
The Veterinary record    May 17, 2005   Volume 156, Issue 20 642-646 doi: 10.1136/vr.156.20.642
Pearson EG, Snyder SP, Saulez MN.The medical records of eight horses with histological evidence of myodegeneration of the masseter muscles were examined. While they were alive their most common clinical signs had included difficulty in eating or opening their mouths, weight loss, difficulty in moving, and noticeable atrophy of the masseter muscles. The serum activities of muscle enzymes were abnormally high in all of the horses. Whole blood and/or liver selenium and vitamin E concentrations were less than the reference ranges in some of the horses. The lesions varied with the stage of the disease and consisted of swelling and...
A study of seven different types of grafts for jugular vein transplantation in the horse.
Research in veterinary science    May 17, 2005   Volume 79, Issue 3 211-217 doi: 10.1016/j.rvsc.2004.12.005
Wiemer P, Gruys E, van Hoeck B.The aim of this study was to investigate the biological behaviour of vascular grafts replacing a section of the jugular vein in order to improve the results of the surgical treatment of complete thrombosis of the jugular vein in the horse. Seven graft types: fresh allograft, home frozen allograft, glutaraldehyde-fixed allograft, cryo-preserved allograft, PTFE-graft (Gore), small intestinal submucosa preparation (Cook) and fresh autograft, were randomly implanted in ponies. The grafts were removed after one month and examined histologically for: preservation of the graft structures, acceptance ...
Electromyographic activity of the stylopharyngeus muscle in exercising horses.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 232-235 doi: 10.2746/0425164054530759
Tessier C, Holcombe SJ, Stick JA, Derksen FJ, Boruta D.There is a need to understand the process which leads to failure of recruitment of the stylopharyngeus muscle in clinical cases of nasopharygeal collapse. We therefore studied the timing and intensity of stylopharyngeus muscle activity during exercise in horses. Objective: To measure the electromyographic (EMG) activity of the stylopharyngeus muscle in exercising horses and correlate it with the breathing pattern. Methods: Five horses were equipped with a bipolar fine wire electrode placed on the stylopharyngeus muscle and a pharyngeal catheter. The horses exercised on a treadmill at speeds co...
Prevalence of Taylorella equigenitalis infection in stallions in Slovenia: bacteriology compared with PCR examination.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 217-221 doi: 10.2746/0425164054530696
Zdovc I, Ocepek M, Gruntar I, Pate M, Klobucar I, Krt B.The prevalence of Taylorella equigenitalis infection in Slovenia is unknown and methods used to refine identification in these stallions are required. Objective: In diagnosis of T. equigenitalis, polymerase chain reaction (PCR) would have advantages over culture methods, especially in cases where small numbers of causal agent or intensive contamination of genital swabs are involved. Methods: Culture method and PCR were used to examine a total of 980 genital swabs from the urethra and fossa urethralis of 245 stallions for the presence of the contagious equine metritis organism. Results: Among 2...
New perspectives for diagnosing equine parasitic disease.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 186-188 doi: 10.2746/0425164054530650
Matthews JB.No abstract available
A new tool for the diagnosis in vivo of habronemosis in horses.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 263-264 doi: 10.2746/0425164054530632
Giangaspero A, Traversa D, Otranto D.No abstract available
Study of serum amyloid A concentrations as a means of achieving early diagnosis of Rhodococcus equi pneumonia.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 212-216 doi: 10.2746/0425164054530704
Cohen ND, Chaffin MK, Vandenplas ML, Edwards RF, Nevill M, Moore JN, Martens RJ.Prognosis of Rhodococcus equi pneumonia can be challenging because the course of the disease is often insidious and overt clinical signs are subtle. Early diagnosis is considered desirable because it may offer the chance of more successful implementation of treatment and, thereby, improved outcome. Serological tests have previously failed to be accurate for early detection or diagnosis. Measurement of serum amyloid A (SAA) prior to and at the time of clinical signs was therefore chosen in order to assess its potential clinical use. Objective: To determine whether SAA concentrations differentia...
Congenital abnormalities of the bicipital apparatus in four mature horses.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 272-275 doi: 10.2746/0425164054530588
Coudry V, Allen AK, Denoix JM.No abstract available
Survey of cardiac arrhythmias during submaximal and maximal exercise in Thoroughbred racehorses.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 265-268 doi: 10.2746/0425164054530713
Ryan N, Marr CM, McGladdery AJ.No abstract available
Influence of repeated arthrocentesis and exercise on synovial fluid concentrations of nitric oxide, prostaglandin E2 and glycosaminoglycans in healthy equine joints.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 250-256 doi: 10.2746/0425164054530740
van den Boom R, van de Lest CH, Bull S, Brama RA, van Weeren PR, Barneveld A.The importance of osteoarthritis (OA) in the horse and the difficulty in its early diagnosis have led to a search for potential biomarkers of joint disease. If the levels of such markers are to be interpreted accurately, clinicians and researchers need to know whether they are influenced by environmental factors and/or interventions such as exercise and repeated arthrocentesis. Objective: To investigate the influence of repeated arthrocentesis and exercise on nitric oxide (NO), prostaglandin E2 (PGE2) and glycosaminoglycan (GAG) concentrations in synovial fluid (SF) from normal equine joints. ...
Effects of glucosamine hydrochloride and chondroitin sulphate, alone and in combination, on normal and interleukin-1 conditioned equine articular cartilage explant metabolism.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 227-231 doi: 10.2746/0425164054530687
Dechant JE, Baxter GM, Frisbie DD, Trotter GW, McIlwraith CW.Clinical trials in human and veterinary literature have documented the benefits of oral nutraceutical joint supplements containing glucosamine (GU) and chondroitin sulphate (CS) to treat mild to moderate osteoarthritis, but the effects of these components have not yet been conclusively determined. Objective: To assess varying dosages of GU and CS on normal and interleukin-1alpha (IL-1) conditioned equine cartilage explants and rationalise the use of these products. Objective: Treatment would not be detrimental to cartilage metabolism and higher dosages and the combination of GU and CS would be...
Influence of species and anatomical location on chondrocyte expansion.
BMC musculoskeletal disorders    May 17, 2005   Volume 6 23 doi: 10.1186/1471-2474-6-23
Akens MK, Hurtig MB.Bovine articular cartilage is often used to study chondrocytes in vitro. It is difficult to correlate in vitro studies using bovine chondrocytes with in vivo studies using other species such as rabbits and sheep. The aim of this investigation was to study the effect of species, anatomical location and exogenous growth factors on chondrocyte proliferation in vitro. Methods: Equine (EQ), bovine (BO) and ovine (OV) articular chondrocytes from metacarpophalangeal (fetlock (F)), shoulder (S) and knee (K) joints were cultured in tissue culture flasks. Growth factors (rh-FGFb: 10 ng/ml; rh-TGFbeta: 5...
Changes to oxfendazole chiral kinetics and anthelmintic efficacy induced by piperonyl butoxide in horses.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 257-262 doi: 10.2746/0425164054530669
Sánchez Bruni SF, Fusé LA, Moreno L, Saumell CA, Alvarez LI, Fiel C, McKellar QA, Lanusse CE.The study of novel pharmacological strategies to control parasitism in horses is required since many parasite species have developed resistance to anthelmintic drugs. Objective: To evaluate the effects of piperonyl butoxide (PB) (a metabolic inhibitor) on the plasma availability and enantiomeric behaviour of oxfendazole (OFZ) given orally to horses, and to compare the clinical efficacy of OFZ given either alone or co-administered with PB in naturally parasitised horses. Methods: Fifteen naturally parasitised crossbred male ponies were allocated into 3 groups (n = 5) and treated orally as follo...
Risk factors for fatal lateral condylar fracture of the third metacarpus/metatarsus in UK racing.
Equine veterinary journal    May 17, 2005   Volume 37, Issue 3 192-199 doi: 10.2746/0425164054530641
Parkin TD, Clegg PD, French NP, Proudman CJ, Riggs CM, Singer ER, Webbon PM, Morgan KL.Lateral condylar fractures of the third metacarpus/metatarsus are the most common cause of equine fatality on UK racecourses. Identification of risk factors for such injuries and the subsequent implementation of intervention strategies could significantly reduce the total number of racecourse fatalities. Objective: To identify horse-, race- and course-level risk factors for fatal lateral condylar fracture in Thoroughbreds on UK racecourses. Methods: Case-control study designs were used. Case horses were defined as those that were subjected to euthanasia having sustained an irreparable lateral ...
Immunoexpression of androgen receptors in the reproductive tract of the stallion.
Annals of the New York Academy of Sciences    May 14, 2005   Volume 1040 227-229 doi: 10.1196/annals.1327.030
Bilinska B, Hejmej A, Gancarczyk M, Sadowska J.The objective of this study was to visualize androgen receptors (ARs) in the testis, epididymis, and prostate of the stallion by means of immunohistochemistry. Nuclear immunostaining was found in all somatic cells in the testis--Leydig, Sertoli, and peritubular myoid cells; in both types of epithelial cells of the epididymis; and in the secretory cells of the prostate. These results indicate that ARs are distributed throughout the reproductive tract cells of the stallion.
Effects of feeding a blend of grains naturally contaminated with Fusarium mycotoxins on feed intake, metabolism, and indices of athletic performance of exercised horses.
Journal of animal science    May 14, 2005   Volume 83, Issue 6 1267-1273 doi: 10.2527/2005.8361267x
Raymond SL, Smith TK, Swamy HV.An experiment was conducted to determine the effect of feeding blends of grains naturally contaminated with Fusarium mycotoxins to mature, exercised horses, and to test the efficacy of a polymeric glucomannan mycotoxin adsorbent (GM polymer) in preventing Fusarium mycotoxicoses. Six mature, mixed-breed mares with an average BW of 530 kg were assigned to one of three dietary treatments for 21 d in a replicated 3 x 3 Latin square design. Feed consumed each day was a combination of up to 3.5 kg of concentrates and 5.0 kg of mixed timothy/alfalfa hay (as-fed basis). The concentrates fed included 1...
The hazards of horse riding.
Australian family physician    May 13, 2005   Volume 34, Issue 5 369-370 
Teixeira F, Punjabi S, Dadzie O, Charakida E, Chu AC.No abstract available
Acute necrotising pancreatitis following grain overload in a donkey.
Australian veterinary journal    May 13, 2005   Volume 82, Issue 10 619-621 doi: 10.1111/j.1751-0813.2004.tb12605.x
Kawaguchi K, Church S, Slocombe RF.A donkey developed abdominal discomfort and distension together with cardiovascular collapse and gastric reflux 24 to 36 hours after ingesting a large amount of poultry feed. Rectal findings prompted a laparotomy that identified extensive gastric dilation, an empty, atonic small intestine, dry colonic content and an easily corrected caecal displacement. These findings were not consistent with the severity of the signs, which were attributed to endotoxaemia. The donkey was euthanased during recovery. Necropsy revealed acute necrotising pancreatitis with massive gastric dilation and right dorsal...
Clostridium septicum arthritis in three foals.
Australian veterinary journal    May 13, 2005   Volume 82, Issue 10 612-615 doi: 10.1111/j.1751-0813.2004.tb12600.x
Kawaguchi K, Church S.This research describes three cases of foals, or young horses, that developed septic arthritis caused by an anaerobic bacterium called Clostridium septicum. All foals were successfully treated with joint irrigation […]
Fracture repair in a draught horse.
Australian veterinary journal    May 13, 2005   Volume 82, Issue 10 623 doi: 10.1111/j.1751-0813.2004.tb12608.x
Stephens WH.No abstract available
A new relaxed state in horse methemoglobin characterized by crystallographic studies.
Proteins    May 12, 2005   Volume 60, Issue 3 547-551 doi: 10.1002/prot.20510
Sankaranarayanan R, Biswal BK, Vijayan M.A new relaxed state has been characterized in the crystals of horse methemoglobin grown at neutral pH at low ionic concentration and their low humidity variants. The crystals provide an example for improvement in X-ray diffraction quality with reduced solvent content. Only the classical R state has been so far observed in liganded horse hemoglobin. The state characterized in the present study lies in between the R state and the R2 state characterized earlier in liganded human hemoglobin. The results presented here, along with those of earlier studies, suggest that relaxed and tense hemoglobin ...
A preliminary equine abuse policy with potential application to veterinary practice.
The Canadian veterinary journal = La revue veterinaire canadienne    May 12, 2005   Volume 46, Issue 3 250-252 
Christie JL, Hewson CJ, Riley CB, McNiven MA, Dohoo IR, Bate LA.An equine abuse policy was developed as an adjunct to an equine management survey. If at least 3 of 5 categories caused concern, a report to the authorities was indicated. The policy was not used but, in the absence of other guidelines, it might assist veterinarians considering potential abuse cases. Dans une enquête sur la gestion équine, un volet portant sur une politique concernant les mauvais traitements infligés aux chevaux a été développée. Lorsqu’au moins 3 des 5 éléments étudiés semblaient problématiques, un rapport aux autorités compétentes était recommandé. La poli...
Genetic immunization with codon-optimized equine infectious anemia virus (EIAV) surface unit (SU) envelope protein gene sequences stimulates immune responses in ponies.
Veterinary microbiology    May 12, 2005   Volume 108, Issue 1-2 23-37 doi: 10.1016/j.vetmic.2005.04.004
Cook RF, Cook SJ, Bolin PS, Howe LJ, Zhou W, Montelaro RC, Issel CJ.In the context of DNA vaccines the native equine infectious anemia virus (EIAV)-envelope gene has proven to be an extremely weak immunogen in horses probably because the RNA transcripts are poorly expressed owing to an unusual codon-usage bias, the possession of multiple RNA splice sites and potential adenosine-rich RNA instability elements. To overcome these problems a synthetic version of sequences encoding the EIAV surface unit (SU) envelope glycoprotein was produced (SYNSU) in which the codon-usage bias was modified to conform to that of highly expressed horse and human genes. In transfect...
Prevalence and risk factors associated with outcome of surgical removal of pedunculated lipomas in horses: 102 cases (1987-2002).
Journal of the American Veterinary Medical Association    May 11, 2005   Volume 226, Issue 9 1529-1537 doi: 10.2460/javma.2005.226.1529
Garcia-Seco E, Wilson DA, Kramer J, Keegan KG, Branson KR, Johnson PJ, Tyler JW.To determine the prevalence of pedunculated lipomas and identify risk factors affecting postoperative complications and survival in horses at a veterinary teaching hospital undergoing surgery for colic caused by pedunculated lipomas. Methods: Retrospective study. Methods: 102 horses with a diagnosis of pedunculated lipoma. Methods: Age, breed, weight, and sex of horses with pedunculated lipomas were compared with the total equine hospital population and the population of horses admitted for abdominal surgery during the same period. Follow-up information was obtained by reevaluation or contact ...