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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Cecal perforation and communication with the retroperitoneal space after cecal impaction in a thoroughbred gelding.
The Canadian veterinary journal = La revue veterinaire canadienne    November 1, 1996   Volume 37, Issue 11 685-687 
Klohnen A, Wilson DG, Cooley AJ.No abstract available
Pathomorphological findings in a case of onychomycosis of a racehorse.
The Journal of veterinary medical science    November 1, 1996   Volume 58, Issue 11 1117-1120 doi: 10.1292/jvms.58.11_1117
Kuwano A, Oikawa M, Takatori K.The hooves of a racehorse which were affected with white line disease and hoof wall disorders on both forelimbs were histopathologically investigated using thin ground section and standard paraffin section techniques. On both hooves, large quantities of fungus were found to have invaded the white line tissues, especially in the terminal horn which were markedly damaged. The fungus was also present among the cellular debris in the fissures of horny tissues. The morphological characteristics of the fungus were brown (its natural color), PAS-positive, mold-like shape with septa inside the tissues...
Effects of road transport on indices of stress in horses.
Equine veterinary journal    November 1, 1996   Volume 28, Issue 6 446-454 doi: 10.1111/j.2042-3306.1996.tb01616.x
Smith BL, Jones JH, Hornof WJ, Miles JA, Longworth KE, Willits NH.Stress associated with road transport is believed to be a significant contributor to the pathogenesis of post transport respiratory disease in horses. To determine the effects of road transport on pulmonary function, pulmonary aerosol clearance rates were measured in 4 horses 24 h before, and immediately after, 24 h of road transport by delivering aerosolised 99mtechnetium-labelled diethylenetriaminepentacetate (99mTc-DTPA) to the lungs and monitoring its washout. Each horse was transported twice, once while the trailer was equipped with a leaf-spring suspension and bias-ply tyres (trailer's o...
High-speed exercise history and catastrophic racing fracture in thoroughbreds.
American journal of veterinary research    November 1, 1996   Volume 57, Issue 11 1549-1555 
Estberg L, Stover SM, Gardner IA, Drake CM, Johnson B, Ardans A.To investigate the relation between several racing speed history characteristics and risk of fatal skeletal injury (FSI) in racing Thoroughbreds. Methods: 64 Thoroughbreds euthanatized during a 9-month period in 1991 at a California racemeet because of a catastrophic fracture incurred while racing (cases), identified retrospectively. For each race in which an FSI occurred, 1 control horse was randomly selected from the noncatastrophically injured participants. Methods: Racing and officially timed workout histories were obtained for each horse. Several history characteristics were calculated to...
Scanning electron microscopy of the equine oviduct and observations on ciliary currents in vitro at day 2 after ovulation.
Theriogenology    November 1, 1996   Volume 46, Issue 7 1305-1311 doi: 10.1016/s0093-691x(96)00302-0
Ball BA.There are considerable differences between mammalian species in the distribution and activity of ciliated cells within the oviduct, and limited information is available concerning either the distribution or activity of cilia within the equine oviduct. Patterns of ciliary activity were characterized in the ampulla and isthmus of oviducts recovered at 2 d after ovulation from 10 mares, and scanning electron microscopy was used to examine regional differences in the distribution of cilia in oviducts from 3 of these mares. Based upon the motility of 15 microm latex microspheres, ciliary activity w...
What is your diagnosis? Squamous cell carcinoma of the paranasal sinuses in a horse.
Journal of the American Veterinary Medical Association    November 1, 1996   Volume 209, Issue 9 1555-1556 
Kemper DL, Walker MA, Morris EL, Schumacher J.No abstract available
Atypical villonodular synovitis in a horse.
Journal of the American Veterinary Medical Association    November 1, 1996   Volume 209, Issue 9 1602-1603 
Vickers KL, Ross MW.A 4-year-old sexually intact male Standardbred trotter was evaluated for left forelimb lameness. A presumptive diagnosis of severe cartilage damage was made because the horse had a history of infectious arthritis involving the left metacarpophalangeal joint. Arthroscopic evaluation revealed what was presumed to be a large villonodular lesion. The mass was surgically removed, and the horse was treated with procaine penicillin G, trimethoprim-sulfamethoxazole, phenylbutazone, and polysulfated glycosaminoglycans and eventually returned to racing. Histologic examination of the mass revealed a bed ...
Role of carbohydrates in the attachment of equine spermatozoa to uterine tubal (oviductal) epithelial cells in vitro.
American journal of veterinary research    November 1, 1996   Volume 57, Issue 11 1635-1639 
Dobrinski I, Ignotz GG, Thomas PG, Ball BA.To test the hypotheses that the attachment of equine spermatozoa to uterine tubal (oviductal) epithelial cells (OEC) in vitro is mediated by glycoproteins, and that proteins with carbohydrate-binding properties are present in the periacrosomal plasma membrane of equine spermatozoa. Methods: 4 reproductively sound stallions, and 1 mare in estrus. Methods: In experiment 1a, fluorescent-labeled spermatozoa were cocultured with monolayers of OEC in the presence of 50 mM glucose, fructose, galactose, mannose, N-acetyl glucosamine, N-acetyl galactosamine, or N-acetyl neuraminic acid, or 10 mg of fet...
Glyceryl trinitrate enhances nitric oxide mediated perfusion within the equine hoof.
The Journal of endocrinology    November 1, 1996   Volume 151, Issue 2 R1-R8 doi: 10.1677/joe.0.151r001
Hinckley KA, Fearn S, Howard BR, Henderson IW.Laminitis, a microvascular disease of the equine hoof leads to severe lameness. Exogenous iv 1-arginine and transdermal nitric oxide donors, such as GTN, applied to the pasterns improve lameness during acute laminitis. Near Infrared spectroscopy in an earlier study showed haemostasis and ischaemia in the hoof during acute laminitis, both were alleviated by 1-arginine. Quantitative NIRS in the present study shows that transdermal GTN increases blood flow in the equine hoof. It is concluded that glyceryl trinitrate enhances nitric oxide mediated perfusion within the equine hoof in normal and chr...
Modulation of matrix metalloprotease 13 (collagenase 3) gene expression in equine chondrocytes by interleukin 1 and corticosteroids.
American journal of veterinary research    November 1, 1996   Volume 57, Issue 11 1631-1634 
Caron JP, Tardif G, Martel-Pelletier J, DiBattista JA, Geng C, Pelletier JP.To determine whether matrix metalloprotease 13 (MMP-13; collagenase 3) is produced by equine chondrocytes and to investigate modulation of its expression by recombinant human interleukin 1 beta (rhIL-1 beta) and corticosteroids. Methods: Equine chondrocytes in monolayer culture were stimulated with rhIL-1 beta. Total RNA was extracted, purified, and reverse transcribed into DNA. Using appropriate primers, a putative MMP-13 fragment was amplified by polymerase chain reaction, and cloned into a bacterial vector. The resultant fragment was purified and sequenced, then was used to prepare a digoxi...
Equine motor neuron disease is not linked to Cu/Zn superoxide dismutase mutations: sequence analysis of the equine Cu/Zn superoxide dismutase cDNA.
Gene    October 31, 1996   Volume 178, Issue 1-2 83-88 doi: 10.1016/0378-1119(96)00339-3
de la Rúa-Domènech R, Wiedmann M, Mohammed HO, Cummings JF, Divers TJ, Batt CA.The cDNA encoding the equine copper/zinc superoxide dismutase (SOD1) was cloned from leukocyte total RNA from healthy horses and its nucleotide (nt) sequence was determined. We further sequenced the SOD1 gene from 16 horses diagnosed with equine motor neuron disease (EMND) and eight unrelated, clinically normal horses to determine if this disease, similar to amyotrophic lateral sclerosis (ALS) in humans, is linked to SOD1 mutations. The 465-bp SOD1 coding region in the horse encodes 153 amino acid (aa) residues. Equine SOD1 exhibited 81.8 and 79.9% sequence identity to the human homolog at the...
Babesiosis in a foal.
The Veterinary record    October 26, 1996   Volume 139, Issue 17 428 
Silvey RE.No abstract available
Identification of an alternatively spliced transcript of equine interleukin-1 beta.
Gene    October 24, 1996   Volume 177, Issue 1-2 11-16 doi: 10.1016/0378-1119(96)00262-4
Kato H, Youn HY, Ohashi T, Watari T, Goitsuka R, Tsujimoto H, Hasegawa A.Using lipopolysaccharide (LPS)-stimulated equine peripheral blood mononuclear cell (PBMC) cDNA as a template, we performed polymerase chain reaction (PCR) amplification with equine interleukin-1 beta (IL-1 beta) specific primers. Electrophoresis of the PCR product on agarose gel revealed an additional smaller fragment that hybridized with an equine IL-1 beta cDNA probe. Sequencing of this fragment demonstrated that it was shorter than normal equine IL-1 beta cDNA by 162 nucleotides, which corresponded to exon 5 of the human and murine IL-1 beta genes. The deletion of 162 nucleotides did not re...
Use of two in vitro methods for the detection of benzimidazole resistance in equine small strongyles (Cyathostoma spp.).
Veterinary parasitology    October 15, 1996   Volume 65, Issue 1-2 117-125 doi: 10.1016/0304-4017(96)00936-3
Ihler CF, Bjørn H.Ten stables were included in a study to evaluate two in vitro methods for the detection of anthelmintic resistance in cyathostomes by comparing a faecal egg count reduction test (FECRT) to a larval development assay (LDA) and an egg hatch assay (EHA). The LDA was used in seven stables and EHA in the last three. On the basis of FECR values, resistance to benzimidazoles was detected in eight of the ten small strongyle populations. Resistance to pyrantel pamoate and ivermectin was not detected. The mean concentrations that inhibited hatching in 50% of the eggs (EC50), using thiabendazole (TBZ) in...
Acute small intestinal injury associated with hematomas in the mesentery of four horses.
Journal of the American Veterinary Medical Association    October 15, 1996   Volume 209, Issue 8 1453-1456 
Van Hoogmoed L, Snyder JR.Four horses were evaluated for clinical signs consistent with small intestinal disease. During exploratory surgery, primary hematomas in the mesentery were found in 2 horses. The third horse developed a hematoma secondary to a mesenteric rent, whereas in the fourth horse, a hematoma developed secondary to strangulation of the bowel by a mesenteric lipoma. Two horses were euthanatized at surgery, because the extensive nature of the hematoma precluded ligation and there was substantial risk of continued hemorrhage postoperatively. The remaining horses recovered from surgery but developed complic...
Theriogenology question of the month. Transrectal palpation used to diagnose uterine torsion in a horse.
Journal of the American Veterinary Medical Association    October 15, 1996   Volume 209, Issue 8 1395-1396 
Perkins NR, Hardy J, Frazer GS, Threlfall WR.No abstract available
What is your diagnosis? Bilateral fragmentation of the fourth maxillary premolar teeth attributable to impaction by adjacent teeth.
Journal of the American Veterinary Medical Association    October 15, 1996   Volume 209, Issue 8 1393-1394 
Dunkerley SA, Hanson RR.No abstract available
Solid-phase extraction and derivatisation methods for beta-blockers in human post mortem whole blood, urine and equine urine.
Journal of chromatography. B, Biomedical applications    October 11, 1996   Volume 685, Issue 1 67-80 doi: 10.1016/0378-4347(96)00140-5
Black SB, Stenhouse AM, Hansson RC.This paper details various rapid and sensitive methods for the extraction and derivatisation of propranolol, metoprolol, sotalol, atenolol, pindolol, timolol, oxprenolol, alprenolol and penbutolol in equine urine and in human post mortem whole blood and urine. Three solid-phase extraction methods are described involving the use of either XtrackT XRDAH515, Bond Elut Certify or Sep-Pak C18 cartridges. Two derivatisation methods are also described involving the formation of cyclised silyl or pentafluoropropionate derivatives with either chloromethyldimethylchlorosilane or pentafluoropropionic anh...
Interaction of GroEL with conformational states of horse cytochrome c.
Journal of molecular biology    October 4, 1996   Volume 262, Issue 4 575-587 doi: 10.1006/jmbi.1996.0536
Hoshino M, Kawata Y, Goto Y.GroEL interacts with proteins in denatured states and promotes their efficient folding. To understand the conformational features required for the substrate, we studied the interactions of GroEL with various derivatives of horse cytochrome c including porphyrin-cytochrome c, apo-cytochrome c, and the three fragments containing the heme group, i.e. fragments 1-65, 1-38 and 11-21. Size-exclusion chromatography was performed, taking advantage of the heme absorption of the fluorescence label. Under low-salt conditions, significant binding to GroEL was observed for porphyrin-cytochrome c, apo-cytoc...
Intracranial hematoma in experienced teenage equestrians.
Pediatric neurology    October 1, 1996   Volume 15, Issue 3 235-236 doi: 10.1016/s0887-8994(96)00162-2
McAbee GN, Ciminera PF.Intracranial hematoma in pediatric equestrians is rare, notwithstanding the lack of uniform standards and requirements for the use of protective headgear during equestrian events. We report two teenage helmeted equestrians who sustained severe head trauma with intracranial hematoma due to falls during equestrian events. Current recommendations for the use of equestrian headgear are reviewed.
[A pony with a metastasized hemangiosarcoma].
Tijdschrift voor diergeneeskunde    October 1, 1996   Volume 121, Issue 19 544-546 
Geelen SN, Sloet van Oldruitenborgh-Oosterbaan MM.A splenic hemangiosarcoma with multiple organ metastases in a pony is reported. Clinical signs included weakness and pallor. Abdominal paracentesis revealed haemorrhagic fluid. Laboratory data included anaemia, thrombocytopenia and hypoproteinaemia. Necropsy findings included a haemangiosarcoma in the spleen with metastases in the lung, liver, kidney and omentum.
DNA polymorphism of the ryanodine receptor gene, exon 17 among six equus species.
Animal genetics    October 1, 1996   Volume 27, Issue 5 376 doi: 10.1111/j.1365-2052.1996.tb00990.x
Ishida N, Hasegawa T, Mukoyama H.No abstract available
Correlation between anatomic features and low-field magnetic resonance imaging of the equine metacarpophalangeal joint.
American journal of veterinary research    October 1, 1996   Volume 57, Issue 10 1421-1426 
Martinelli MJ, Baker GJ, Clarkson RB, Eurell JC, Pijanowski GJ, Kuriashkin IV, Carragher BO.To expand our current knowledge and to establish limits of correlation between signal intensities of the magnetic resonance (MR) image and actual macroscopic and microscopic anatomic features of the imaged structures of the equine metacarpophalangeal joint (MCPJ). Methods: The right MCPJ was obtained from 4 adult horses that were euthanatized for reasons unrelated to the musculoskeletal system. Methods: The distal portion of the right forelimbs was collected from 4 equine cadavers. The bones were drilled to provide fixed reference points and examined by MR imaging. After imaging, the joints we...
Clinical and pathological aspects of an outbreak of equine leukoencephalomalacia in Spain.
Zentralblatt fur Veterinarmedizin. Reihe A    October 1, 1996   Volume 43, Issue 8 467-472 doi: 10.1111/j.1439-0442.1996.tb00476.x
Naranjo Cerrillo G, Soler Rodríguez F, Gómez Gordo L, Hermoso de Mendoza Salcedo M, Roncero Cordero V.In 1988 an outbreak of leukoencephalomalacia was diagnosed in equids that had eaten corn with a pinkish fungal growth. The fungus was then identified as Fusarium moniliforme. The main symptoms observed appeared acutely and were overexcitement, blindness, incoordination, facial paralysis and death within 24 h. The main pathological changes were restricted to the central nervous system. Macroscopically they consisted of hyperemia and haemorrhages, the consistency was friable and the gyri were somewhat flattened. Microscopically, the lesions were profuse and had extensive haemorrhages, and numero...
[Enantioselectivity in the excretion of glucuronides of carprofen in man, dogs and horses].
Bulletin de l'Academie nationale de medecine    October 1, 1996   Volume 180, Issue 7 1565-1572 
Delatour P, Garnier F, Maire R.After administration of the racemic drug, the stereoselective quantification of the enantiomers of free and conjugated carprofen was performed in human plasma and in plasma, urine and bile of dogs and horses. In humans, the plasma profile of free carprofen and its glucuronides is not stereoselective and the glucuronides excreted in urine are close to a racemate. In dogs and horses on the contrary, the R(-) enantiomer of the free drug is predominant in plasma, while urine and/or bile concentrations of the glucuronides are high in comparison to plasma with a strong selectivity for the S(+) enant...
[Use of a mix of lidocaine and butorphanol as a caudal epidural anesthesia in a mare].
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire    October 1, 1996   Volume 60, Issue 4 288-295 
Csik-Salmon J, Blais D, Vaillancourt D, Garon O, Bisaillon A.Loss of rear motor control is the main limiting factor in the use of caudal epidural anesthesia in the horse. In man and laboratory animals, a small dose of an opiate combined with a local anesthetic enhances analgesia without impairing motor function. Thus, the amount of local anesthetic administered may be reduced. Butorphanol is an opiate widely used in horses. It has a good margin of safety and few cardiorespiratory effects. The effects of lidocaine (0.25 mg/kg) and lidocaine-butorphanol (0.25 mg/kg, and 0.04 mg/kg, respectively) were compared in 2 groups of 5 healthy unsedated mares. Hors...
Nucleologenesis and ribonucleic acid synthesis in preimplantation equine embryos.
Biology of reproduction    October 1, 1996   Volume 55, Issue 4 769-774 doi: 10.1095/biolreprod55.4.769
Grøndahl C, Hyttel P.The nucleolus is believed to be the active site of rRNA synthesis in all eukaryotic cells. In preimplantation embryos, the embryonic genome is apparently more or less silent up to a species-specific developmental stage at which a major burst of transcription occurs. Here we report on nucleologenesis and some ultrastructural aspects of the onset of RNA synthesis in equine embryos during in vivo development. The zygotes and embryos up to blastocyst stages were surgically recovered from normally cycling mares. Mares were induced to ovulate by treatment with 3000 IU hCG and inseminated 20 and 34 h...
Extra-pulmonary Rhodococcus equi in a thoroughbred foal.
The Canadian veterinary journal = La revue veterinaire canadienne    October 1, 1996   Volume 37, Issue 10 623-624 
Nay TS.No abstract available
[Endoparasites of donkeys and horses kept in communal housing in Upper Bavaria; species spectrum and incidence].
Tierarztliche Praxis    October 1, 1996   Volume 24, Issue 5 471-475 
Beelitz P, Göbel E, Gothe R.In this epidemiological study of endoparasites 37 donkeys and 23 horses were included, which were examined coproscopically in regular intervals over a 15 month period. The animals derived from ten farms, in which regular prophylactic treatments with anthelmintics had been practiced at least for two years before this investigation. This study revealed the presence of at least twelve parasite species in donkeys, Eimeria leuckarti, Gasterophilus intestinalis, Fasciola hepatica, Anoplocephala perfoliata, Strongyloides westeri, Parascaris equorum, Dictyocaulus arnfieldi, Trichostrongylus axei and s...
Mechanism of exercise-induced augmentation of lymphokine activated killer (LAK) cell activity in the horse.
Veterinary immunology and immunopathology    October 1, 1996   Volume 53, Issue 3-4 221-233 doi: 10.1016/S0165-2427(96)05610-3
Horohov DW, Keadle TL, Pourciau SS, Littlefield-Chabaud MA, Kamerling SG, Keowen ML, French DD, Melrose PA.Intense exercise affects various parameters of the immune system. The overall effect of exercise on immune function is dependent upon the physical condition of the subject, the intensity and duration of the exercise period, and the immune parameter assessed. Unconditioned horses subjected to a single bout of intensive exercise exhibit multiple alterations in immune function, including an augmentation of lymphokine activated killer (LAK) cell function. This increase in LAK cell activity is not due to an increase in circulating LAK precursors. While peripheral blood mononuclear cells from exerci...