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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Endogenous toxins and mycotoxins in forage grasses and their effects on livestock.
Journal of animal science    March 1, 1995   Volume 73, Issue 3 909-918 doi: 10.2527/1995.733909x
Cheeke PR.Plant toxins are the chemical defenses of plants against herbivory. Grasses have relatively few intrinsic toxins, relying more on growth habit to survive defoliation and endophytic fungal toxins as chemical defenses. Forage grasses that contain intrinsic toxins include Phalaris spp. (tryptamine and carboline alkaloids), sorghums (cyanogenic glycosides), and tropical grasses containing oxalates and saponins. Toxic effects of these grasses include neurological damage (Phalaris staggers), hypoxia (sudangrass), saponin-induced photosensitization (Brachiaria and Panicum spp.), and bone demineraliza...
Abnormal patterns of equine leucocyte differentiation antigen expression in severe combined immunodeficiency foals suggests the phenotype of normal equine natural killer cells.
Immunology    March 1, 1995   Volume 84, Issue 3 495-499 
Lunn DP, McClure JT, Schobert CS, Holmes MA.Severe combined immunodeficiency (SCID) is a fatal autosommal disease of Arabian horses that leads to failure of maturation of T- and B-lymphocyte populations, although natural killer (NK) cells are unaffected. Thymic and lymph node tissues from two foals suffering from SCID were examined in an immunohistological study using a panel of monoclonal antibodies recognising equine leucocyte differentiation antigens. In both foals, the majority of cells in lymphoid tissues had an EqCD3-EqCD4-EqCD8+ phenotype, although rare EqCD3+ cells were also detected. The EqCD3-EqCD4-EqCD8+ cells may represent a...
Large colon impaction in horses: 147 cases (1985-1991).
Journal of the American Veterinary Medical Association    March 1, 1995   Volume 206, Issue 5 679-685 
Dabareiner RM, White NA.Medical records from all horses with large colon impaction admitted between 1985 and 1991 were examined. Large colon impaction was diagnosed in 147 of 1,100 (13.4%) horses with colic. One hundred thirty horses were admitted for further evaluation of acute onset of abdominal pain after having been examined and treated by referring veterinarians, and 17 horses that were hospitalized for unrelated medical problems developed large colon impaction. Female horses (92/147; 62.6%) were more commonly affected than males. The age ranged from 1 to 29 years (median, 7.1 years). Mean duration of clinical s...
Recent developments in elucidating tick vector relationships for anaplasmosis and equine piroplasmosis.
Veterinary parasitology    March 1, 1995   Volume 57, Issue 1-3 97-108 doi: 10.1016/0304-4017(94)03114-c
Stiller D, Coan ME.This brief review focuses first on several epidemiologically relevant aspects of anaplasmosis, including: (1) the role of male ticks as intrastadial, biological vectors of Anaplasma through interhost transfer; (2) the application of molecular diagnostic assays in assessing tick vector competence and evaluating the role of chronically infected carrier cattle as sources of Anaplasma marginale infection in vector ticks; (3) opportunities provided by a recently developed in vitro tick feeding system in quantitating studies of tick-hemoparasite-host interactions. Lastly, current knowledge of the st...
Management factors associated with stereotypic and redirected behaviour in the thoroughbred horse.
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 86-91 doi: 10.1111/j.2042-3306.1995.tb03041.x
McGreevy PD, Cripps PJ, French NP, Green LE, Nicol CJ.A greater knowledge of the effect of management factors is required to investigate the ontogeny of abnormal behaviour in the stabled horse. A postal survey of racehorse (flat) trainers yielded information about 22 yard and management factors. The relationship of the factors to the prevalence of abnormal behaviour was analysed by logistic regression. Management factors related to the time spent in the stable showed the strongest associations with stereotypic behaviour. The risk of horses performing abnormal behaviour increased: 1) as the amount of forage fell below 6.8 kg/day, 2) when bedding t...
Development of a colic severity score for predicting the outcome of equine colic.
Veterinary surgery : VS    March 1, 1995   Volume 24, Issue 2 97-101 doi: 10.1111/j.1532-950x.1995.tb01302.x
Furr MO, Lessard P, White NA.Thirty-two physical examination and laboratory variables were recorded during examination of 165 horses admitted for acute abdominal disease. Univariate analyses were performed to determine which of the variables were significantly different between horses that lived or died. Stepwise logistic regression was performed to identify variables with the best predictive value. Four variables (heart rate, peritoneal fluid total protein concentration, blood lactate concentration, and abnormal mucous membrane) remained significant when entered into the model. Histograms for each significant variable we...
In vitro 19-norandrogen synthesis by equine placenta requires the participation of aromatase.
The Journal of endocrinology    March 1, 1995   Volume 144, Issue 3 517-525 doi: 10.1677/joe.0.1440517
Moslemi S, Silberzahn P, Gaillard JL.Explants of equine full-term placenta have been shown to synthesize 19-norandrogens from labelled androgens. Steroid metabolites were purified by silica-gel column chromatography then analysed and quantified by c18-reverse-phase HPLC coupled to a radioactive flow detector. 19-Norandrostenedione was subsequently recrystallized to constant specific activity, providing unequivocal evidence of its synthesis by the equine placenta. 19-Norandrostenedione synthesis appeared to be localized in the microsomal fraction. Regardless of the substrate used, formation of 19-norandrogens was far weaker than t...
Pulmonary perfusion and ventilation: a mismatch?
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 80-81 doi: 10.1111/j.2042-3306.1995.tb03038.x
Schatzmann U.No abstract available
The prevalence of intestinal Salmonella infection in horses submitted for necropsy.
The Onderstepoort journal of veterinary research    March 1, 1995   Volume 62, Issue 1 65-67 
van Rensburg IB, Jardine JE, Carstens JH, van der Walt ML.Specimens from the ileum, colon and rectum were aseptically collected from 50 consecutive horse carcases submitted for necropsy to the Department of Pathology, Faculty of Veterinary Science, University of Pretoria. These were bacteriologically examined for the presence of Salmonella. Seventeen of these were positive for Salmonella at one or more sites. Serotyping of the isolates revealed a dominance of Salmonella Hayindogo in these horses.
Isolation of obligate anaerobic bacteria from clinical specimens.
The Canadian veterinary journal = La revue veterinaire canadienne    March 1, 1995   Volume 36, Issue 3 173 
Hariharan H, Lamey K, Heaney S.No abstract available
Local and remote matrix responses to chondrocyte-laden collagen scaffold implantation in extensive articular cartilage defects.
Osteoarthritis and cartilage    March 1, 1995   Volume 3, Issue 1 61-70 doi: 10.1016/s1063-4584(05)80038-x
Sams AE, Minor RR, Wootton JA, Mohammed H, Nixon AJ.Chondrocyte-laden collagen scaffolds were evaluated in extensive cartilage defects in an equine model. Arthroscopic techniques were used to implant a chondrocyte-collagen culture product in 15-mm defects in the lateral trochlear ridge of the femoropatellar joint of 12 horses. Ungrafted control defects were formed in the opposite joint. Groups of six horses were terminated at 4 and 8 months after implantation and the repair sites, adjacent cartilage, and remote cartilage within each femoropatellar joint examined biochemically. Eight months following surgery the relative proportions of type II c...
Congenital corneal vascularisation in a neonatal Thoroughbred foal.
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 156-157 doi: 10.1111/j.2042-3306.1995.tb03055.x
Munroe GA.No abstract available
Surgical treatment of fractures of the tibial tuberosity in 6 adult horses.
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 96-102 doi: 10.1111/j.2042-3306.1995.tb03043.x
Wright IM, Montesso F, Kidd LJ.This paper describes the clinical and radiological features, surgical techniques used and results obtained in 6 horses with fractures of the tibial tuberosity. The horses were presented between 24 h and 8 weeks following injury. In all 6 cases, the fragments were displaced proximocranially and in 2 of these, there was comminution. Four were treated by open reduction and internal fixation using an AO/ASIF narrow dynamic compression plate and in 2 cases the fragments were removed. All horses returned to full athletic function and remained sound in follow-up times of 17-36 months. Implant removal...
Iridium-192 interstitial brachytherapy for equine periocular tumours: treatment results and prognostic factors in 115 horses.
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 117-121 doi: 10.1111/j.2042-3306.1995.tb03046.x
Théon AP, Pascoe JR.One hundred and fifteen horses with periocular tumours were treated with iridium-192 interstitial brachytherapy. Tumours included squamous cell carcinomas (n = 52) and sarcoids (n = 63). All horses were scheduled to receive 60 Gy (minimal tumour dose) given at a low dose rate (0.034 +/- 0.010 Gy/h). The mean and median follow-up times to last contact or death were 24 and 16 months, respectively. Chronic radiation reactions included palpebral fibrosis (10.4%), cataract (7.8%), keratitis and corneal ulceration (6.9%). Cosmetic changes included permanent epilation (21.7%) and hair dyspigmentation...
Acetylcholine release from airway cholinergic nerves in horses with heaves, an airway obstructive disease.
American journal of respiratory and critical care medicine    March 1, 1995   Volume 151, Issue 3 Pt 1 830-835 doi: 10.1164/ajrccm/151.3_Pt_1.830
Wang ZW, Yu MF, Robinson NE, Derksen FJ.The present study was conducted to determine if acetylcholine (ACh) release from airway cholinergic nerves is increased and if modulation of ACh release by prejunctional receptors is altered in horses with heaves, an obstructive airway disease characterized by airway inflammation and bronchospasm. Trachealis strips and bronchial segments of normal horses and horses affected with heaves were suspended in 2-ml tissue baths. ACh release was induced by electrical field stimulation and the bath ACh content was measured by high performance liquid chromatography (HPLC) with electrochemical detection....
New perspectives on equine stereotypic behaviour.
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 82-83 doi: 10.1111/j.2042-3306.1995.tb03039.x
Houpt KA.No abstract available
Immunohistochemical localisation of steroidogenic enzymes and phenylethanolamine-N-methyl-transferase (PNMT) in the adrenal gland of the fetal and newborn foal.
Equine veterinary journal    March 1, 1995   Volume 27, Issue 2 140-146 doi: 10.1111/j.2042-3306.1995.tb03051.x
Han X, Fowden AL, Silver M, Holdstock N, McGladdery AJ, Ousey JC, Allen WR, Rossdale PD, Challis JR.An increase in fetal adrenal cortisol output signals the onset of parturition in many animal species but, in the fetal horse, plasma concentrations of cortisol remain low for much of late pregnancy, with a rise occurring only very close to the time of birth (term 320-360 days). Immunohistochemistry was used to determine the localisation and changes in distribution of key steroidogenic enzymes for cortisol production; P450scc, P450C17 and 3 beta-hydroxysteroid dehydrogenase (3 beta HSD) in adrenal tissue from fetal and newborn horses and these findings were correlated with the appearance of imm...
Measurement of upper airway pressures in exercising horses with dorsal displacement of the soft palate.
American journal of veterinary research    March 1, 1995   Volume 56, Issue 3 269-274 
Rehder RS, Ducharme NG, Hackett RP, Nielan GJ.To determine whether abnormal airway pressures have a role in development of dorsal displacement of the soft palate (DDSP), measurements of tracheal and pharyngeal pressures were correlated with nasopharyngeal morphology in exercising horses. Exercising videoendoscopy and measurement of tracheal and pharyngeal pressures were used in 14 clinically normal horses and 19 horses with intermittent DDSP. The pressure signals were superimposed on the videoendoscope image, and both images were saved simultaneously on a videocassette for slow motion analysis to determine the instant displacement occurre...
Behavioural studies in healthy ponies subjected to short-term forced recumbency aiming at an adjunctive treatment in an acute attack of laminitis.
Zentralblatt fur Veterinarmedizin. Reihe A    March 1, 1995   Volume 42, Issue 1 62-68 doi: 10.1111/j.1439-0442.1995.tb00356.x
Wattle O, Ekfalck A, Funkquist B, Obel N.The authors postulated that a period of forced recumbency during an acute attack of laminitis may counteract the disabling effects on the secondary epidermal laminae. On the basis of this concept a study was made of the behavior of three healthy Shetland ponies when placed in a box in which the ceiling was too low for a standing position but allowed comfortable sternal recumbency. When the height of the box was about 125% of the vertical distance between the withers and the sternum, the ponies lay calmly during most of the experimental period and the rare attempts at rising did not seem to put...
Endoscopy of the upper respiratory tract during treadmill exercise: a clinical study of 100 horses.
Australian veterinary journal    March 1, 1995   Volume 72, Issue 3 101-107 doi: 10.1111/j.1751-0813.1995.tb15020.x
Kannegieter NJ, Dore ML.Endoscopy of the upper respiratory tract was performed in 100 horses during high speed treadmill exercise. Reasons for endoscopy were a history of an abnormal noise during exercise in 75 horses, poor performance in 17 horses and to evaluate the results of upper respiratory tract surgery in 8 horses. Of the 75 horses with a history of an abnormal noise during exercise the cause was determined in 67 (89%). Endoscopic abnormalities were detected at rest in 40 of these 75 horses (53%). In these 40 horses, a similar diagnosis as to the cause of the abnormal noise was made at rest and during exercis...
Anti-collagen antibodies and immune complexes in equine joint diseases.
Veterinary immunology and immunopathology    March 1, 1995   Volume 45, Issue 1-2 19-30 doi: 10.1016/0165-2427(94)05325-m
Osborne AC, Carter SD, May SA, Bennett D.An investigation was made into the possible contribution of autoimmune mechanisms to equine arthropathies. Serum and synovial fluid (SF) immune complexes and anti-collagen Type II antibodies were measured, by ELISA, in groups of horses with naturally occurring osteoarthritis (OA), osteochondritis dissecans (OCD), bone fracture, traumatised joints, synovitis, infected joints and non-diseased (control) joints. Significantly raised anti-collagen Type II antibodies were found in osteoarthritic (P < 0.02) and traumatised joint synovial fluids (P < 0.01) compared with the control, where ten of...
Differences in a ribosomal DNA sequence of Strongylus species allows identification of single eggs.
International journal for parasitology    March 1, 1995   Volume 25, Issue 3 359-365 doi: 10.1016/0020-7519(94)00116-6
Campbell AJ, Gasser RB, Chilton NB.In the current study, molecular techniques were evaluated for the species identification of individual strongyle eggs. Adult worms of Strongylus edentatus, S. equinus and S. vulgaris were collected at necropsy from horses from Australia and the U.S.A. Genomic DNA was isolated and a ribosomal transcribed spacer (ITS-2) amplified and sequenced using polymerase chain reaction (PCR) techniques. The length of the ITS-2 sequence of S. edentatus, S. equinus and S. vulgaris ranged between 217 and 235 nucleotides. Extensive sequence analysis demonstrated a low degree (0-0.9%) of intraspecific variation...
Intraperitoneal use of sodium carboxymethylcellulose in horses undergoing exploratory celiotomy.
Veterinary surgery : VS    March 1, 1995   Volume 24, Issue 2 112-117 doi: 10.1111/j.1532-950x.1995.tb01304.x
Mueller PO, Hunt RJ, Allen D, Parks AH, Hay WP.The effect of intraperitoneal sodium carboxymethylcellulose (SCMC) administration on clinical outcome and survival was evaluated in horses undergoing exploratory celiotomy for acute gastrointestinal disease. Comparison of variables was made retrospectively between 44 horses that had SCMC and 92 horses (controls) not treated with SCMC. Mean age, body weight, heart rate, packed cell volume and plasma total protein of horses at admission, and convalescent period were not significantly different between control and SCMC groups. No significant differences were noted between control horses and SCMC ...
Enantioselective glucuronidation and subsequent biliary excretion of carprofen in horses.
American journal of veterinary research    March 1, 1995   Volume 56, Issue 3 358-361 
Soraci A, Benoit E, Jaussaud P, Lees P, Delatour P.Carprofen (CPF) enantiomers and their glucuronide conjugates (GLUC) were measured in plasma and bile of horses after IV administration of the racemic compound (0.7 mg/kg of body weight). The CPF was detectable in plasma for up to 72 hours after dosing, whereas GLUC appeared early (time for maximal plasma concentration, 1 hour) and was measurable transiently at low concentration (maximal plasma concentration, 0.5 microgram/ml). The enantiospecific plasma profiles indicated a clear predominance of R-CPF, whereas the stereoselectivity of the glucuronides favored S-GLUC. At 1, 2, and 12 hours afte...
Identification of the causative agent of granulocytic ehrlichiosis in Swedish dogs and horses by direct solid phase sequencing of PCR products from the 16S rRNA gene.
Research in veterinary science    March 1, 1995   Volume 58, Issue 2 109-112 doi: 10.1016/0034-5288(95)90061-6
Johansson KE, Pettersson B, Uhlén M, Gunnarsson A, Malmqvist M, Olsson E.Seven Swedish isolates of Ehrlichia species from the blood of four dogs and three horses with clinical granulocytic ehrlichiosis, were identified by direct solid phase DNA sequencing of polymerase chain reaction (PCR) products from the 16S rRNA gene. The amplified DNA fragments were produced with primers complementary to the universal regions, U1, U2, U5 and U8 of the 16S rRNA molecule. Identical sequences were obtained from all seven isolates. This nucleotide sequence was similar to the sequences deposited in GenBank for Ehrlichia phagocytophila and E equi. The sequence of the Swedish ehrlich...
Influence of stochastic events on the phenotypic variation of common white leg markings in the Arabian horse: implications for various genetic disorders in humans.
The Journal of heredity    March 1, 1995   Volume 86, Issue 2 129-135 doi: 10.1093/oxfordjournals.jhered.a111542
Woolf CM.One method of assessing the influence of stochastic events on phenotypic variation is to study morphological differences in paired limbs of the same individual. These limbs have identical genotypes and similar intra-uterine environments and are analogous to monozygotic twins. Common white leg markings have a multifactorial mode of inheritance in the Arabian horse. Asymmetry occurs frequently for these markings. Using computerized registration records obtained from the Arabian Horse Registry of America, Inc., the types of markings were quantified in the left foreleg and left hind leg of bay and...
Antiphagocytic properties of uterine isolates of Streptococcus zooepidemicus and mechanisms of killing in freshly obtained blood of horses.
American journal of veterinary research    March 1, 1995   Volume 56, Issue 3 321-328 
Causey RC, Paccamonti DL, Todd WJ.A total of 22 clinical streptococcal isolates, predominantly Streptococcus zooepidemicus, associated with endometritis in horses were tested for their ability to withstand the natural bactericidal properties of freshly obtained blood. During a 3-hour incubation in blood from a single horse, 8 of these isolates survived and grew, the remainder were killed. To determine whether this ability to grow extended to blood of other horses, 5 of these growing isolates were tested for their ability to grow in the blood of 5 additional horses. The same 5 horses were used for each isolate. The isolates gre...
Spontaneous equine pulmonary granular cell tumors: morphologic, histochemical, and immunohistochemical characterization.
Veterinary pathology    March 1, 1995   Volume 32, Issue 2 101-106 doi: 10.1177/030098589503200201
Kelley LC, Hill JE, Hafner S, Wortham KJ.Spontaneous equine pulmonary granular cell tumors were diagnosed in six mature horses at slaughter. These tumors were grossly recognized as multiple (5/6) or single (1/6) creamy white, firm nodules. The tumors, located adjacent to bronchi and bronchioles, often invaded airways, resulting in partial to complete occlusion of the lumina. Neoplastic cells were rounded to polyhedral with numerous eosinophilic cytoplasmic granules that reacted uniformly positive with S-100 and neuron-specific enolase antibodies and multifocally with glial fibrillary acidic protein antibodies. These cells were negati...
Overestimation of copper deficiency in horses?
The Veterinary record    February 25, 1995   Volume 136, Issue 8 203-204 doi: 10.1136/vr.136.8.203
Bathe AP, Cash R.No abstract available
Epidemiology of the equine influenza outbreak in China, 1993-94.
The Veterinary record    February 18, 1995   Volume 136, Issue 7 160-161 doi: 10.1136/vr.136.7.160
Shortridge KF, Chan WH, Guan Y.No abstract available