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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Pathology of equine pneumonia associated with transport and isolation of Streptococcus equi subsp. zooepidemicus.
Journal of comparative pathology    August 1, 1994   Volume 111, Issue 2 205-212 doi: 10.1016/s0021-9975(05)80052-0
Oikawa M, Kamada M, Yoshikawa Y, Yoshikawa T.Seven horses that died of pneumonia associated with transport yielded Streptococcus equi subsp. zooepidemicus (S.z.) from their pulmonary lesions. These lesions were divisible roughly into two types, serous haemorrhagic pneumonia and multiple foci of coagulative necrosis, which were considered to reflect a temporal difference in the process of lesion formation. Immunohistologically, S.z. antigen was detected in both types of lesion. Acute necrotic lacunar tonsillitis was considered to play an important role in the onset of the pneumonia.
[Doping problems in horse sports–pharmacokinetics of selected antiphlogistics/analgesics relevant to doping].
DTW. Deutsche tierarztliche Wochenschrift    August 1, 1994   Volume 101, Issue 8 331-338 
Klaus AM, Hapke HJ.Drug treatment of horses which are used in horse-racing is restricted by the regulations of the anti-doping control. Veterinarians and anti-doping control commissions are faced with the problems resulting from the discrepancy between the demand "no drugs in blood/urine of horses at the time of competition" and the need for treatment. The pharmacokinetic data of important antiphlogistics/analgetics (NSAID) for horses given in this article shall facilitate the decision of the veterinarians and commissions whether a horse having been treated with NSAID may participate in a competition or not. Fur...
Clinicopathological observations on thoroughbred foals with enlarged thyroid gland.
The Journal of veterinary medical science    August 1, 1994   Volume 56, Issue 4 771-772 doi: 10.1292/jvms.56.771
Osame S, Ichijo S.Seven cases of thoroughbred foals kept on a farm in the Hidaka district of Hokkaido showed bilateral thyroid enlargement from 3 or 4 months after birth. Their serum T4 levels were remarkably low, whereas T3 levels were in the normal range. Serum T4 levels were also low in the other clinically normal foals and their dams kept together. Since the iodine content in pasture soil and grass was very low, iodine deficiency was supposed to be the cause of the disease.
Models of the three-dimensional structures of echidna, horse, and pigeon lysozymes: calcium-binding lysozymes and their relationship with alpha-lactalbumins.
Journal of protein chemistry    August 1, 1994   Volume 13, Issue 6 569-584 doi: 10.1007/BF01901539
Acharya KR, Stuart DI, Phillips DC, McKenzie HA, Teahan CG.Similarities in amino acid sequences, three-dimensional structures, and the exon-intron patterns of their genes have indicated that c-type lysozymes and alpha-lactalbumins are homologous proteins, i.e., descended by divergent evolution from a common ancestor. Like the alpha-lactalbumins, echidna milk, horse milk, and pigeon eggwhite lysozymes all bind Ca(II). Models of their three-dimensional structures, based on their amino acid sequences and the known crystal structures of domestic hen eggwhite and human lysozymes and baboon and human alpha-lactalbumins, have been built. The several structur...
Functional anatomy of tendons and ligaments in the distal limbs (manus and pes).
The Veterinary clinics of North America. Equine practice    August 1, 1994   Volume 10, Issue 2 273-322 doi: 10.1016/s0749-0739(17)30358-9
Denoix JM.Tendons and ligaments of the equine distal limbs have a prominent anatomic, functional, and clinical importance. This article reviews the descriptive and topographic anatomy of these structures in details. Special information is given about the mechanical properties and functional anatomy of the flexor tendons, accessory ligaments, and third interosseous muscle, as well as about their roles during the standing position and gaits.
Inhibition of binding, entry, or intracellular proliferation of Ehrlichia risticii in P388D1 cells by anti-E. risticii serum, immunoglobulin G, or Fab fragment.
Infection and immunity    August 1, 1994   Volume 62, Issue 8 3156-3161 doi: 10.1128/iai.62.8.3156-3161.1994
Messick JB, Rikihisa Y.The effects of equine antiserum, immunoglobulin G (IgG) specific for Ehrlichia risticii, and its Fab fragment on E. risticii binding to, internalization into, and proliferation in P388D1 cells were studied by immunofluorescence flow cytometry. Anti-E. risticii equine serum or IgG inhibited E. risticii at a stage beyond binding and internalization. In contrast, monovalent anti-E. risticii equine Fab fragments inhibited E. risticii binding and internalization into P388D1 cells. In the presence of control equine serum, IgG, or its Fab fragment, E. risticii cells were bound, were internalized and ...
Characterization of monoclonal antibodies specific for equine homologues of CD3 and CD5.
Immunology    August 1, 1994   Volume 82, Issue 4 548-554 
Blanchard-Channell M, Moore PF, Stott JL.Two monoclonal antibodies (mAb), UC F6G-3 and UC F13C-5, were characterized as being specific for the apparent equine homologues of CD3 and CD5, respectively. Both antibodies exhibited characteristics of pan-T-lymphocyte markers based upon immunohistology and two-colour flow cytometry. UC F6G-3 precipitated a complex of proteins (up to seven) with molecular weights ranging from 18,000 to 42,000, similar to the human and murine CD3 complex. Upon further dissociation of the precipitated complex, two proteins were identified with molecular weights of 22,000 and 27,000. Immobilized UC F6G-3 was ef...
Treatment of superficial digital flexor tendinitis.
The Veterinary clinics of North America. Equine practice    August 1, 1994   Volume 10, Issue 2 409-424 doi: 10.1016/s0749-0739(17)30362-0
Henninger R.This article reviews the research and clinical findings relevant to the treatment of acute tendinitis in the horse. The goals of treatment are to reduce inflammation, minimize scar tissue formation, and promote restoration of normal tendon function. A wide variety of treatments have and still are being used to treat tendinitis, which indicates that there is no uniformly successful way to return a horse to full athletic function after injury. Therapy depends on the severity of tendinitis and duration of injury and can be divided into treatment during the inflammatory, repair, and maturation pha...
The immunology of companion animals: reagents and therapeutic strategies with potential veterinary and human clinical applications.
Immunology today    August 1, 1994   Volume 15, Issue 8 347-353 doi: 10.1016/0167-5699(94)90171-6
Cobbold S, Holmes M, Willett B.There is now a wide range of immunological reagents that can be used in the diagnosis and treatment of diseases in the companion animals (dogs, cats and horses). Many of these diseases are the veterinary equivalents of human conditions, and may therefore provide good models to study basic pathogenic mechanisms.
A subpopulation of morphologically normal, motile spermatozoa attach to equine oviductal epithelial cell monolayers.
Biology of reproduction    August 1, 1994   Volume 51, Issue 2 303-309 doi: 10.1095/biolreprod51.2.303
Thomas PG, Ball BA, Miller PG, Brinsko SP, Southwood L.Attachment of spermatozoa to oviductal epithelial cells (OEC) may be a prefertilization event in some species. We tested the hypothesis that spermatozoa that attach to equine OEC monolayers are a selected subpopulation of the initial inseminate, containing a higher proportion of morphologically normal, motile cells than the inseminate. Washed stallion spermatozoa were cocultured with monolayers of OEC or monolayers of Vero cells, and controls were incubated in wells coated with basement membrane extract (Matrigel [Mgel]) or in plastic (uncoated) wells. Unattached spermatozoa were removed by ri...
Molecular dynamics simulation of equine infectious anemia virus Tat protein in water and in 40% trifluoroethanol.
Journal of biomolecular structure & dynamics    August 1, 1994   Volume 12, Issue 1 019-36 
Sticht H, Willbold D, Rösch P.Two molecular dynamics (MD) simulations were performed in order to increase the understanding of the dependence of protein conformation on solvent environment. The protein used for these simulations is the transcriptional activator of the equine infectious anemia virus (EIAV-Tat). The structure of this protein has been determined by nuclear magnetic resonance (NMR) in aqueous solution (Willbold et al., Science 264, 1584 (1994)) and in 40% (v/v) trifluoroethanol (TFE) (Sticht et al., Eur. J. Biochem., submitted) showing considerable differences in the stability of the secondary structure elemen...
Practical management of superficial digital flexor tendinitis in the performance horse.
The Veterinary clinics of North America. Equine practice    August 1, 1994   Volume 10, Issue 2 425-481 doi: 10.1016/s0749-0739(17)30363-2
Palmer SE, Genovese R, Longo KL, Goodman N, Dyson S.The authors of this section represent a broad range of practice experience with horses that perform in rigorous and varied sport competitions. Each breed and performance application represent unique challenges of diagnosis and uncompromising demands on rehabilitated tendon injuries. This article will serve to guide, stimulate, and encourage veterinarians to apply scientific criteria to the evaluation of tendinitis therapy in the years to come so that we can arrive at a more valid consensus as to the "best" means of tendon and ligament injury management.
Characterization of the antiphagocytic activity of equine fibrinogen for Streptococcus equi subsp. equi.
Microbial pathogenesis    August 1, 1994   Volume 17, Issue 2 121-129 doi: 10.1006/mpat.1994.1058
Boschwitz JS, Timoney JF.The antiphagocytic property of equine fibrinogen for Streptococcus equi subsp. equi strain CF32 was examined in vitro. The results of bactericidal assays demonstrated that the presence of fibrinogen enhanced the ability of overnight and early log-phase cultures of strain CF32 to resist killing by equine neutrophils by 12-fold and seven-fold, respectively (p > 0.01). In addition, fibrinogen-coated bacteria treated with fibrinogen specific F(ab')2 fragments were 32% more susceptible to killing by equine neutrophils after opsonization in serum (p > 0.05), indicating that specific epitopes o...
Characteristics of cyclicity in maiden thoroughbred mares in the United Kingdom.
The Veterinary record    July 30, 1994   Volume 135, Issue 5 104-106 doi: 10.1136/vr.135.5.104
Watson ED, McDonnell AM, Cí·¯ord D.The characteristics of the cyclicity of 12 maiden thoroughbred mares kept in two groups were studied over a total of 58 cycles. On average, oestrus lasted 5.3 days and in 60 per cent of the cycles ovulation occurred in the last two days of oestrus. Oestrus and ovulation tended to be synchronised in each group of mares. The mean diameter of single-ovulating preovulatory follicles on the day before ovulation was 41.5 mm and during the seven days before ovulation they grew 2.5 mm/day. More than one follicle ovulated in 19 (33 per cent) of the cycles (seven double ovulations and 12 dioestrous ovul...
Autonomic neurons from horses with grass sickness contain serum proteins.
The Veterinary record    July 23, 1994   Volume 135, Issue 4 90-91 doi: 10.1136/vr.135.4.90
Griffiths IR, Smith S, Kyriakides E, Barrie JM.No abstract available
Fluctuating asymmetry in racehorses.
Nature    July 21, 1994   Volume 370, Issue 6486 185-186 doi: 10.1038/370185a0
Manning JT, Ockenden L.No abstract available
Effects of treatment with ivermectin for five years on the prevalence of Anoplocephala perfoliata in three Louisiana pony herds.
The Veterinary record    July 16, 1994   Volume 135, Issue 3 63-65 doi: 10.1136/vr.135.3.63
French DD, Chapman MR, Klei TR.No abstract available
Isolation of equine herpesvirus type 2 (equine gammaherpesvirus 2) from foals with keratoconjunctivitis.
Journal of the American Veterinary Medical Association    July 15, 1994   Volume 205, Issue 2 329-331 
COllinson PN, O'Rielly JL, Ficorilli N, Studdert MJ.Ocular problems characterized by conjunctivitis, epiphora, and keratopathy were detected in 35 of 80 Thoroughbred weanling foals that also had respiratory disease. Ocular problems were determined to be caused by infection with equine herpesvirus type 2 (EHV-2) and were successfully treated with ophthalmic medication containing idoxuridine. Equine herpesvirus type 2 isolated from 3 of 5 foals from which samples were collected. The identity of the causative virus as EHV-2 was confirmed by use of electron microscopy, restriction endonuclease DNA fingerprinting, and Southern blot analysis.
Peritonitis associated with Actinobacillus equuli in horses: 15 cases (1982-1992).
Journal of the American Veterinary Medical Association    July 15, 1994   Volume 205, Issue 2 340-343 
Golland LC, Hodgson DR, Hodgson JL, Brownlow MA, Hutchins DR, Rawlinson RJ, Collins MB, McClintock SA, Raisis AL.Peritonitis attributable to Actinobacillus equuli was diagnosed in 15 horses examined at the veterinary center between 1982 and 1992. In 13 horses, historical findings included acute onset of mild to severe signs of abdominal pain, lethargy, and inappetence. Two other horses had a history of weight loss for 3 to 6 weeks prior to examination. Diagnosis was based on the physical signs and laboratory findings, including results of peritoneal fluid analysis (gross characteristics, total protein, total and differential nucleated cell counts, and morphologic findings) and culture of A equuli. Actino...
Partial typhlectomy and ileocolostomy for treatment of nonreducible cecocolic intussusception in a horse.
Journal of the American Veterinary Medical Association    July 15, 1994   Volume 205, Issue 2 325-328 
Ward JL, Fubini SL.Cecocolic intussusception was detected in a 2-year-old male Standardbred horse with a 3-day history of signs of intermittent colic. The entire cecum, which was located within the lumen of the right ventral colon, was edematous and necrotic, and could not be manually reduced. A colotomy was made, and partial typhlectomy was performed. An ileocolostomy also was performed. To prevent eversion of the cecal base, the site of invagination into the colon was oversewn. Several postoperative complications were treated, including peritonitis, thrombophlebitis, anemia, and hypoproteinemia, and 1 year aft...
Denervation atrophy in three horses with fibrotic myopathy.
Journal of the American Veterinary Medical Association    July 15, 1994   Volume 205, Issue 2 332-336 
Valentine BA, Rousselle SD, Sams AE, Edwards RB 3drd .Three horses with fibrotic myopathy were examined for neuromuscular disease. In 2 horses, concentric needle electromyography was performed. Dense spontaneous activity suggestive of denervation, was found in multiple thigh muscles of 1 of the 2 horses. All 3 horses were euthanatized. Histochemical and histologic examination of tissue specimens was performed. All horses had degenerative lesions in peripheral and intramuscular nerves. Angular atrophy of type-1 and type-2 muscle fibers, indicative of denervation atrophy, was seen in multiple muscle specimens from all 3 horses. One horse was found ...
Compounding of drugs in equine practice.
Journal of the American Veterinary Medical Association    July 15, 1994   Volume 205, Issue 2 207-209 
Lenz TR, Kanara EW, Becht JL.No abstract available
Jejunal obstruction caused by a Pythium insidiosum granuloma in a mare.
Journal of the American Veterinary Medical Association    July 15, 1994   Volume 205, Issue 2 337-339 
Purcell KL, Johnson PJ, Kreeger JM, Wilson DA.An 8-year-old Missouri Fox Trotter mare was examined because of intermittent, low-grade abdominal pain and weight loss for 3 months. Incomplete jejunal obstruction, caused by a granulomatous mass in the wall of the jejunum, was identified during exploratory celiotomy. Pythium insidiosum was identified as the cause of the granuloma. This case suggests that enteric pythiosis may develop in horses that are geographically distant from the Gulf Coast.
Is dentition an accurate indication of the age of a horse?
The Veterinary record    July 9, 1994   Volume 135, Issue 2 31-34 doi: 10.1136/vr.135.2.31
Richardson JD, Lane JG, Waldron KR.It is widely accepted that the age of a horse can be determined from an examination of its teeth, but there is no evidence that the accuracy of the systems of ageing used has been validated. A dental record was made of 80 horses of known age. There was a good correlation between the actual and apparent age of the horses up to five years, but older horses showed much greater variability and accuracy declined markedly after 11 years of age. The disappearance of the 'cup', but not the 'mark', proved to be one of the more reliable features. The average age at which the dental star appeared was one...
Polymorphic expression of an equine T lymphocyte and neutrophil subset marker.
Veterinary immunology and immunopathology    July 1, 1994   Volume 42, Issue 1 83-89 doi: 10.1016/0165-2427(94)90091-4
Lunn DP, Holmes MA, Duffus WP.This report describes the further characterization of a group of antibodies which have been assigned to Workshop Cluster 1 by the First International Workshop on Equine Leucocyte Antigens. These antibodies recognize a 22 kDa antigen, which is present on a large subset of T lymphocytes and neutrophils, and on medullary thymocytes. The antigen is polymorphic in its expression, and three equine phenotypes could be identified using the described antibodies. The function and homology of the antigen recognized by these antibodies are unknown.
Density of myenteric plexuses and neurons in the large and transverse colon of one-day-old foals.
Equine veterinary journal    July 1, 1994   Volume 26, Issue 4 337-339 doi: 10.1111/j.2042-3306.1994.tb04397.x
Schusser GF, White NA.No abstract available
Genomic sequences of bovine papillomaviruses in formalin-fixed sarcoids from Australian horses revealed by polymerase chain reaction.
Veterinary microbiology    July 1, 1994   Volume 41, Issue 1-2 163-172 doi: 10.1016/0378-1135(94)90145-7
Bloch N, Breen M, Spradbrow PB.Seventy six formalin-fixed paraffin-embedded sarcoids from 62 Australian horses, collected over a ten year period, were examined for the presence of genomic sequences from bovine papillomavirus 1 and 2 (BPV1, BPV2) with the polymerase chain reaction (PCR). Sequences that could be amplified by primers specific for BPV1 and BPV2 were present in 56 of the 76 sarcoids (73%). A restriction site present in BPV1 and absent from BPV2 was detected in 28 of 34 amplified products that were treated with endonuclease.
Localization of aromatase in equine Leydig cells.
Domestic animal endocrinology    July 1, 1994   Volume 11, Issue 3 291-298 doi: 10.1016/0739-7240(94)90020-5
Eisenhauer KM, McCue PM, Nayden DK, Osawa Y, Roser JF.Stallion testes secrete large amounts of estrogens, but the cellular location of the enzyme that converts androgens to estrogens, cytochrome P450 aromatase, has not been determined. The goal of the present study was to immunocytochemically localize stallion testicular aromatase using a polyclonal antibody generated against human placental cytochrome P450 aromatase. Testes were obtained from 12 stallions from 2 to 23 years of age, during both the breeding and non-breeding seasons. Immunoreactivity was confined to the Leydig cells in all testes examined. No immunostaining was observed in the Ser...
Comparative aspects of the strength of pulmonary capillaries in rabbit, dog, and horse.
Respiration physiology    July 1, 1994   Volume 97, Issue 2 235-246 doi: 10.1016/0034-5687(94)90029-9
Birks EK, Mathieu-Costello O, Fu Z, Tyler WS, West JB.In previous studies of rabbit and dog lung, we demonstrated stress failure of pulmonary capillaries at high transmural pressures (Ptm). The Ptm necessary to elicit stress failure was 40 cmH2O higher in dog than rabbit, and the total blood-gas barrier (BGB) thickness was greater in dog than rabbit. This suggests that stress failure may be related to BGB thickness, and is consistent with the Laplace relationship which states that wall stress is proportional to capillary radius but inversely proportional to wall thickness. In the present studies, we compared BGB thickness and an index of capillar...
Attempts to modify reperfusion injury of equine jejunal mucosa using dimethylsulfoxide, allopurinol, and intraluminal oxygen.
Veterinary surgery : VS    July 1, 1994   Volume 23, Issue 4 241-249 doi: 10.1111/j.1532-950x.1994.tb00478.x
Horne MM, Pascoe PJ, Ducharme NG, Barker IK, Grovum WL.This study compared the severity of ischemic injury to the equine jejunal mucosa caused by arteriovenous obstruction (AVO) or venous obstruction (VO) with that caused by reperfusion after ischemia. The degree of mucosal damage and regeneration was scored according to a modified version of an established light microscopic classification for ischemic injury. Biopsy specimens taken after 3 and 4 hours of obstruction, and after 3 hours of obstruction and 1 hour of reperfusion, were compared. There were no changes in the severity of mucosal injury (characterized by epithelial sloughing, loss of vil...