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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
The effect of intravenous lidocaine infusion on bronchoalveolar lavage cytology in equine recurrent airway obstruction.
Journal of veterinary internal medicine    November 1, 2012   Volume 26, Issue 6 1427-1432 doi: 10.1111/j.1939-1676.2012.01010.x
Wilson ME, Berney C, Behan AL, Robinson NE.Lidocaine decreases neutrophilic inflammation in models of acute lung injury and decreases inflammation in asthmatic patients. Neutrophilic bronchiolitis develops in recurrent airway obstruction (RAO), but it remains unknown if lidocaine infusion decreases neutrophil migration into the airways. Objective: Lidocaine decreases neutrophilic inflammation as measured in BALF in RAO-affected horses. Methods: Six RAO-susceptible horses in remission. Methods: In a randomized cross-over design, horses received lactated Ringer's solution (LRS) IV or lidocaine hydrochloride IV with a minimum of 4 weeks a...
The horse as a model of naturally occurring osteoarthritis.
Bone & joint research    November 1, 2012   Volume 1, Issue 11 297-309 doi: 10.1302/2046-3758.111.2000132
McIlwraith CW, Frisbie DD, Kawcak CE.Osteoarthritis (OA) is an important cause of pain, disability and economic loss in humans, and is similarly important in the horse. Recent knowledge on post-traumatic OA has suggested opportunities for early intervention, but it is difficult to identify the appropriate time of these interventions. The horse provides two useful mechanisms to answer these questions: 1) extensive experience with clinical OA in horses; and 2) use of a consistently predictable model of OA that can help study early pathobiological events, define targets for therapeutic intervention and then test these putative thera...
Serum protein concentrations as predictors of serum immunoglobulin G concentration in neonatal foals.
Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)    November 1, 2012   Volume 22, Issue 5 573-579 doi: 10.1111/j.1476-4431.2012.00794.x
Hurcombe SD, Matthews AL, Scott VH, Williams JM, Kohn CW, Toribio RE.To determine the predictive value of serum concentrations of total protein (sTP), albumin (sAlb), and globulin (sGlob) measured by automated calorimetric assays to estimate serum immunoglobulin G (sIgG) concentrations in neonatal foals and identify failure of transfer of passive immunity when compared to turbidoimmunometric assay determinations of sIgG. Methods: Retrospective and prospective analysis of laboratory data. Methods: University tertiary care facility. Methods: Group 1 (retrospective): foals (n = 45) ≤7 days of age in which sIgG, sGlob, sAlb, and sTP concentrations were measured o...
Relationship of mixed bacterial infection to prognosis in foals with pneumonia caused by Rhodococcus equi.
Journal of veterinary internal medicine    November 1, 2012   Volume 26, Issue 6 1443-1448 doi: 10.1111/j.1939-1676.2012.01023.x
Giguère S, Jordan LM, Glass K, Cohen ND.Isolation of multiple bacterial species is common in foals with Rhodococcus equi pneumonia. Objective: There is no association between isolation of other microorganisms and outcome. Methods: 155 foals with pneumonia caused by R. equi. Methods: Case records of foals diagnosed with R. equi pneumonia based on culture of the respiratory tract were reviewed at 2 referral hospitals (University of Florida [UF] and Texas A&M University [TAMU]). Results: R. equi was cultured from a tracheobronchial aspirate (TBA) in 115 foals and from lung tissue in 38 foals. Survival was significantly higher at UF...
Evaluation of growth models for follicle development and ovulation in Lusitano mares.
Animal reproduction science    November 1, 2012   Volume 136, Issue 1-2 81-84 doi: 10.1016/j.anireprosci.2012.10.026
Mata F.Several growth models are commonly used in the biological sciences, to model the follicle growth occurring in the estrous cycle. The aim of this project was to find the model that best fit the follicular size growth data for Lusitano mares. Retrospective data collected from reproduction book records of n=84 mares and n=124 cycles was used to find the series to be fitted to the models. The exponential, Gompertz, logistic, von Bertalanffy, Richards and Weibull models were used, and the most parsimonious and best fit was achieved with the logistic model (r(2)=0.999). The logistic model fits the L...
An approach to imaging algorithms for equine lameness diagnosis.
The Veterinary clinics of North America. Equine practice    November 1, 2012   Volume 28, Issue 3 467-481 doi: 10.1016/j.cveq.2012.08.007
Charles EM, Rantanen NW.Tremendous growth and advancement in equine diagnostic imaging necessitates a systematic approach to the application of these modalities to lameness diagnosis. This systematic approach must include attention to the history, physical and clinical examinations, and parameters set forth by the client. It also must include an understanding of which imaging modality is most appropriate given the details of the case. This article presents a basic framework with an underlying algorithmic foundation that can be applied when selecting imaging modalities during lameness evaluation and includes case exam...
Epidemiological survey of the hoof wall cavity (‘Gidoh’ in Japanese) in racehorses.
The Veterinary record    November 1, 2012   Volume 171, Issue 24 623 doi: 10.1136/vr.100725
Kuwano A, Yamauchi Y, Sasagawa T, Sasaki N, Hamano H.In October 2001, a survey was conducted about cavities formed within the hoof wall (called GIDOH in Japanese) of racehorses at the Ritto and Miho Training Centres, which are managed by the Japan Racing Association (JRA). Gidoh is defined as a progressive cavity within the deep layers between the stratum medium and stratum internum. A total of 148 out of 5386 surveyed horses (2.75 per cent) were affected. Out of 244 affected feet, fore hooves (84.02 per cent) were more susceptible than hind hooves, and the site most affected was midline dead centre of the toe (59.62 per cent) which tends to pla...
Use of intravenous gadolinium contrast in equine magnetic resonance imaging.
The Veterinary clinics of North America. Equine practice    November 1, 2012   Volume 28, Issue 3 617-636 doi: 10.1016/j.cveq.2012.08.008
Saveraid TC, Judy CE.The use of intravenous gadolinium contrast during equine magnetic resonance imaging (MRI) is a new technique that has been infrequently used in clinical imaging. This article describes the development of an effective contrast dose and the use of gadolinium contrast in clinical equine MRI. Gadolinium contrast improves lesion conspicuity across a broad range of lesion types. Contrast-enhanced MRI is potentially a valuable imaging tool in the assessment of the equine athlete.
Induction of double ovulation in mares using deslorelin acetate.
Animal reproduction science    November 1, 2012   Volume 136, Issue 1-2 69-73 doi: 10.1016/j.anireprosci.2012.10.015
Nagao JF, Neves Neto JR, Papa FO, Alvarenga MA, Freitas-Dell'Aqua CP, Dell'Aqua JA.This study aimed to determine whether deslorelin acetate could induce double ovulation in mares. In Experiment 1, eight mares were treated with prostaglandin on Day 8 (D8) after ovulation, then treated with saline or with 100 μg of a controlled-release formulation of deslorelin acetate vehicle intramuscularly (IM) every 12h from D8 after ovulation until at least two follicles reached 33 mm. At this time, ovulation was induced with 2500 IU of hCG. Artificial insemination was performed 24h after induction, and embryos were collected on the eighth day after ovulation was first detected. In Exper...
Association of breeding conditions with prevalence of osteochondrosis in foals.
The Veterinary record    November 1, 2012   Volume 172, Issue 3 68 doi: 10.1136/vr.101034
Vander Heyden L, Lejeune JP, Caudron I, Detilleux J, Sandersen C, Chavatte P, Paris J, Deliège B, Serteyn D.Osteochondrosis (OC) is the most common developmental orthopaedic disease in horses and represents a major problem to the horse industry. The complete mechanism of this multifactorial disease is not yet elucidated, but it is accepted that OC lesions are the result of intrinsic genetic and external factors. The aim of the present work was to evaluate the relationship between breeding management and OC. Breeding conditions were recorded, and a radiological examination was performed in 223 foals. Feeding practice and housing management were analysed in a multivariate model to determine risk facto...
Endocrinological aspects of the pathophysiology of equine laminitis.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 735-737 doi: 10.1111/j.2042-3306.2012.00663.x
Menzies-Gow N.No abstract available
Investigation of hydration processes of the equine hoof via nuclear magnetic resonance microscopy.
American journal of veterinary research    October 31, 2012   Volume 73, Issue 11 1775-1780 doi: 10.2460/ajvr.73.11.1775
Sugimoto M, Kuwano A, Ikeda S, Kume S, Yoshihara E, Wada S.To examine the distribution of water in hoof wall specimens of horses via nuclear magnetic resonance (NMR) microscopy and determine changes in water distribution during hydration. Methods: 4 hoof wall specimens (2 obtained from the dorsum and 1 each obtained from the lateral quarter and lateral heel regions) of the stratum medium of healthy hooves of 1 horse. Methods: Equine hoof wall specimens were examined via NMR microscopy. Proton density-weighted 3-D images were acquired. Changes during water absorption were assessed on sequential images. Results: The inner zone of the stratum medium had ...
Chronicle of a death foretold.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 631-632 doi: 10.1111/j.2042-3306.2012.00665.x
Riggs CM.No abstract available
Imaging or imagining? Is equine diagnostic imaging evidence based?
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 629-630 doi: 10.1111/j.2042-3306.2012.00660.x
Weller R.No abstract available
Respiratory responses to exercise in the horse.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 726-732 doi: 10.1111/j.2042-3306.2012.00666.x
Franklin SH, Van Erck-Westergren E, Bayly WM.Horses are elite athletes when compared with other mammalian species. In the latter, performance is limited by cardiovascular or musculoskeletal performance whereas in athletic horses it is the respiratory system that appears to be rate limiting and virtually all horses exercising at high intensities become hypoxaemic and hypercapnoeic. This is due to both diffusion limitation and a level of ventilation inadequate for the metabolic level that enables horses to exercise at these intensities. In conjunction with these blood gas changes, total pulmonary resistance increases and the work of breath...
Sepsis-related laminitis.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 738-740 doi: 10.1111/j.2042-3306.2012.00668.x
Belknap JK, Black SJ.No abstract available
Guttural pouch mycosis in horses: a retrospective study of 28 cases.
The Veterinary record    October 31, 2012   Volume 171, Issue 22 561 doi: 10.1136/vr.100700
Dobesova O, Schwarz B, Velde K, Jahn P, Zert Z, Bezdekova B.The medical records of 28 horses with guttural pouch mycosis were reviewed. The most commonly observed clinical signs were nasal discharge, epistaxis, dysphagia and/or cough. All 28 horses had the disease unilaterally, however, in five of them, it had spread into the contralateral pouch via the mesial septum. Three horses were treated medically, 11 horses underwent surgery and seven horses were treated both medically and surgically. Fifty percent of horses (14/28) were euthanased or died, fifty percent of horses (14/28) survived. There was no significant correlation between treatment method (m...
Explaining spatial heterogeneity in population dynamics and genetics from spatial variation in resources for a large herbivore.
PloS one    October 31, 2012   Volume 7, Issue 10 e47858 doi: 10.1371/journal.pone.0047858
Contasti AL, Tissier EJ, Johnstone JF, McLoughlin PD.Fine-scale spatial variation in genetic relatedness and inbreeding occur across continuous distributions of several populations of vertebrates; however, the basis of observed variation is often left untested. Here we test the hypothesis that prior observations of spatial patterns in genetics for an island population of feral horses (Sable Island, Canada) were the result of spatial variation in population dynamics, itself based in spatial heterogeneity in underlying habitat quality. In order to assess how genetic and population structuring related to habitat, we used hierarchical cluster analys...
Profound re-organization of cell surface proteome in equine retinal pigment epithelial cells in response to in vitro culturing.
International journal of molecular sciences    October 31, 2012   Volume 13, Issue 11 14053-14072 doi: 10.3390/ijms131114053
Szober CM, Hauck SM, Euler KN, Fröhlich KJ, Alge-Priglinger C, Ueffing M, Deeg CA.The purpose of this study was to characterize the cell surface proteome of native compared to cultured equine retinal pigment epithelium (RPE) cells. The RPE plays an essential role in visual function and represents the outer blood-retinal barrier. We are investigating immunopathomechanisms of equine recurrent uveitis, an autoimmune inflammatory disease in horses leading to breakdown of the outer blood-retinal barrier and influx of autoreactive T-cells into affected horses' vitrei. Cell surface proteins of native and cultured RPE cells from eye-healthy horses were captured by biotinylation, an...
Laminitis: recent advances and future directions.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 733-734 doi: 10.1111/j.2042-3306.2012.00671.x
Marr CM.No abstract available
Investigation of forelimb hoof wall strains and hoof shape in unshod horses exercised on a treadmill at various speeds and gaits.
American journal of veterinary research    October 31, 2012   Volume 73, Issue 11 1735-1741 doi: 10.2460/ajvr.73.11.1735
Bellenzani MC, Merritt JS, Clarke S, Davies HM.To investigate forelimb hoof wall strains and shape changes in unshod horses undergoing regular moderate exercise on a treadmill at selected speeds and gaits. Methods: 6 horses of various body types. Methods: Each horse was exercised on a treadmill (walking, trotting, and cantering, with or without galloping at 12.5 m/s) 3 times a week for 4 consecutive weeks; duration of each exercise session ranged from 10 to 14 minutes. During the 4-week period, the proximal hoof circumference (PHC) and toe angle (TA) of each forelimb hoof were measured weekly with a flexible measuring tape and a hoof gauge...
The present state and future of laminitis research.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 749-751 doi: 10.1111/j.2042-3306.2012.00669.x
Belknap J, Geor R.No abstract available
Where does it hurt?
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 627-628 doi: 10.1111/j.2042-3306.2012.00661.x
Barr AR.No abstract available
Mechanical and morphological properties of trabecular bone samples obtained from third metacarpal bones of cadavers of horses with a bone fragility syndrome and horses unaffected by that syndrome.
American journal of veterinary research    October 31, 2012   Volume 73, Issue 11 1742-1751 doi: 10.2460/ajvr.73.11.1742
Symons JE, Entwistle RC, Arens AM, Garcia TC, Christiansen BA, Fyhrie DP, Stover SM.To determine morphological and mechanical properties of trabecular bone of horses with a bone fragility syndrome (BFS; including silicate-associated osteoporosis). Methods: Cylindrical trabecular bone samples from the distal aspects of cadaveric third metacarpal bones of 39 horses (19 horses with a BFS [BFS bone samples] and 20 horses without a BFS [control bone samples]). Methods: Bone samples were imaged via micro-CT for determination of bone volume fraction; apparent and mean mineralized bone densities; and trabecular number, thickness, and separation. Bone samples were compressed to failur...
A predictive model for reproductive performance following abortion in Thoroughbred mares.
The Veterinary record    October 31, 2012   Volume 172, Issue 2 44 doi: 10.1136/vr.100670
Schulman ML, Kass PH, Becker A, Van der Merwe B.Pregnancy losses include early embryonic death (EED) and later (postimplantation) abortion. Abortions, particularly Equid herpesvirus (EHV-1) abortion epizootics, cause severe economic and production losses. The long-term effects of EHV-1 and other abortions on subsequent reproductive performance in broodmare populations, however, remain undefined. This study described the relationships of EED and abortion with the following reproductive outcomes in Thoroughbred systems: breeding efficiency, month of last breeding, subsequent pregnancy and live foal rates. A prospective cohort study in broodma...
Effects of high-intensity training on lipid metabolism in Thoroughbreds.
American journal of veterinary research    October 31, 2012   Volume 73, Issue 11 1813-1818 doi: 10.2460/ajvr.73.11.1813
Kitaoka Y, Mukai K, Aida H, Hiraga A, Masuda H, Takemasa T, Hatta H.To investigate the effects of high-intensity training (HIT) on carbohydrate and fat metabolism in Thoroughbreds. Methods: 12 Thoroughbreds (3 to 4 years old; 6 males and 6 females). Methods: Horses performed HIT for 18 weeks. They ran at 90% or 110% of maximal oxygen consumption ((V)O(2max)) for 3 minutes (5 d/wk) and were subjected to incremental exercise testing (IET) before and after training. Blood samples were collected during IET, and muscle samples were obtained from the gluteus medius muscle immediately after IET. Phosphofructokinase, citrate synthase, and β-3-hydroxyacyl CoA dehydrog...
Progress towards effective prevention and therapy for laminitis.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 746-748 doi: 10.1111/j.2042-3306.2012.00667.x
van Eps AW.No abstract available
Supporting limb laminitis: the four important ‘whys’.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 741-745 doi: 10.1111/j.2042-3306.2012.00662.x
Orsini JA.No abstract available
A review of recent advances and current hypotheses on the pathogenesis of acute laminitis.
Equine veterinary journal    October 31, 2012   Volume 44, Issue 6 752-761 doi: 10.1111/j.2042-3306.2012.00664.x
Katz LM, Bailey SR.With the increasing number of studies being published on the different experimental models used to induce and study acute laminitis, the pathophysiological events associated with these various models (i.e. starch overload, oligofructose overload, black walnut extract and hyperinsulinaemia) can be compared more realistically. Within this review, the mechanisms for metabolic vs. inflammatory laminitis are discussed, and the question of how pasture laminitis may fit into any of the proposed mechanisms is addressed.
Ivermectin inhibits growth of Chlamydia trachomatis in epithelial cells.
PloS one    October 30, 2012   Volume 7, Issue 10 e48456 doi: 10.1371/journal.pone.0048456
Pettengill MA, Lam VW, Ollawa I, Marques-da-Silva C, Ojcius DM.Ivermectin is currently approved for treatment of both clinical and veterinary infections by nematodes, including Onchocerca cervicalis in horses and Onchocerca volvulus in humans. However, ivermectin has never been shown to be effective against bacterial pathogens. Here we show that ivermectin also inhibits infection of epithelial cells by the bacterial pathogen, Chlamydia trachomatis, at doses that could be envisioned clinically for sexually-transmitted or ocular infections by Chlamydia.