Analyze Diet

Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
A recombinant Hendra virus G glycoprotein-based subunit vaccine protects ferrets from lethal Hendra virus challenge.
Vaccine    July 1, 2011   Volume 29, Issue 34 5623-5630 doi: 10.1016/j.vaccine.2011.06.015
Pallister J, Middleton D, Wang LF, Klein R, Haining J, Robinson R, Yamada M, White J, Payne J, Feng YR, Chan YP, Broder CC.The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), are two deadly zoonotic viruses for which no vaccines or therapeutics have yet been approved for human or livestock use. In 14 outbreaks since 1994 HeV has been responsible for multiple fatalities in horses and humans, with all known human infections resulting from close contact with infected horses. A vaccine that prevents virus shedding in infected horses could interrupt the chain of transmission to humans and therefore prevent HeV disease in both. Here we characterise HeV infection in a ferret model and show that it closely mirror...
Evidence-based medicine in bovine, equine and canine reproduction: quality of current literature.
Theriogenology    June 30, 2011   Volume 76, Issue 6 1042-1050 doi: 10.1016/j.theriogenology.2011.05.007
Simoneit C, Heuwieser W, Arlt S.The objective was to evaluate deficits and differences of published literature on reproduction in cattle, horses, and dogs. A literature search was conducted in the databases Medline and Veterinary Science. Approximately five times more articles on clinical bovine reproduction (n = 25 910) were found compared to canine (n = 5 015) and equine (n = 5 090) reproduction. For the evaluation of the literature, a checklist was used. A subset of 600 articles published between 1999 and 2008 was randomly selected. After applying exclusion criteria, a total of 268 trials (86 for cattle, 99 for horses, an...
The SnSAG merozoite surface antigens of Sarcocystis neurona are expressed differentially during the bradyzoite and sporozoite life cycle stages.
Veterinary parasitology    June 30, 2011   Volume 183, Issue 1-2 37-42 doi: 10.1016/j.vetpar.2011.06.024
Gautam A, Dubey JP, Saville WJ, Howe DK.Sarcocystis neurona is a two-host coccidian parasite whose complex life cycle progresses through multiple developmental stages differing at morphological and molecular levels. The S. neurona merozoite surface is covered by multiple, related glycosylphosphatidylinositol-linked proteins, which are orthologous to the surface antigen (SAG)/SAG1-related sequence (SRS) gene family of Toxoplasma gondii. Expression of the SAG/SRS proteins in T. gondii and another related parasite Neospora caninum is life-cycle stage specific and seems necessary for parasite transmission and persistence of infection. I...
Evaluation of LHP® (1% hydrogen peroxide) cream versus petrolatum and untreated controls in open wounds in healthy horses: a randomized, blinded control study.
Acta veterinaria Scandinavica    June 30, 2011   Volume 53, Issue 1 45 doi: 10.1186/1751-0147-53-45
Tóth T, Broström H, Båverud V, Emanuelson U, Bagge E, Karlsson T, Bergvall K.Treatment and protection of wounds in horses can be challenging; protecting bandages may be difficult to apply on the proximal extremities and the body. Unprotected wounds carry an increased risk of bacterial contamination and subsequent infection which can lead to delayed wound healing. Topical treatment with antimicrobials is one possibility to prevent bacterial colonization or infection, but the frequent use of antimicrobials ultimately leads to development of bacterial resistance which is an increasing concern in both human and veterinary medicine. Methods: Standardized wounds were created...
Characteristics of the equine embryo and fetus from days 15 to 107 of pregnancy.
Theriogenology    June 30, 2011   Volume 76, Issue 5 819-832 doi: 10.1016/j.theriogenology.2011.04.014
Franciolli AL, Cordeiro BM, da Fonseca ET, Rodrigues MN, Sarmento CA, Ambrosio CE, de Carvalho AF, Miglino MA, Silva LA.In spite of numerous, substantial advances in equine reproduction, many stages of embryonic and fetal morphological development are poorly understood, with no apparent single source of comprehensive information. Hence, the objective of the present study was to provide a complete macroscopic and microscopic description of the equine embryo/fetus at various gestational ages. Thirty-four embryos/fetuses were aged based on their crown rump length (CRL), and submitted to macroscopic description, biometry, light and scanning microscopy, as well as the alizarin technique. All observed developmental c...
Does immunotherapy protect equines from reinfection by the oomycete Pythium insidiosum?
Clinical and vaccine immunology : CVI    June 29, 2011   Volume 18, Issue 8 1397-1399 doi: 10.1128/CVI.05150-11
Santos CE, Marques LC, Zanette RA, Jesus FP, Santurio JM.A cutaneous Pythium insidiosum reinfection was diagnosed in an equine in Brazil. Lesions with focal presentation appeared 2 years apart. The first infection and even immunotherapy were not likely to develop enough immune response to prevent reinfection. The use of adjuvants should be considered in the immunotherapy of pythiosis.
Inoculation of young horses with bovine papillomavirus type 1 virions leads to early infection of PBMCs prior to pseudo-sarcoid formation.
The Journal of general virology    June 29, 2011   Volume 92, Issue Pt 10 2437-2445 doi: 10.1099/vir.0.033670-0
Hartl B, Hainisch EK, Shafti-Keramat S, Kirnbauer R, Corteggio A, Borzacchiello G, Tober R, Kainzbauer C, Pratscher B, Brandt S.Bovine papillomavirus types 1 and 2 (BPV-1 and BPV-2) are known to induce common equine skin tumours, termed sarcoids. Recently, it was demonstrated that vaccination with BPV-1 virus-like particles (VLPs) is safe and highly immunogenic in horses. To establish a BPV-1 challenge model for evaluation of the protective potential of BPV-1 VLPs, four foals were injected intradermally with infectious BPV-1 virions and with viral genome-based and control inocula, and monitored daily for tumour development. Blood was taken before inoculation and at weekly intervals. BPV-1-specific serum antibodies were...
Comparison of radiographic and scintigraphic findings of the spinous processes in the equine thoracolumbar region. Zimmerman M, Dyson S, Murray R.Back pain is common in horses, but there has been no large-scale in-depth study describing radiographic changes of the spinous processes, the relationship between radiographic and scintigraphic findings, and the effect of size, age, breed, or discipline. The objectives were to investigate the frequency of occurrence in horses with perceived back pain of: (1) radiographic alteration of the spinous process structure; (2) increased radiopharmaceutical uptake (IRU) in the spinous processes; and (3) to compare radiographic and scintigraphic findings; and to determine if there was breed, gender, age...
Inhalation with NDS27 attenuates pulmonary neutrophilic inflammation in recurrent airway obstruction.
The Veterinary record    June 28, 2011   Volume 169, Issue 4 100 doi: 10.1136/vr.d2618
Sandersen C, Olejnik D, Franck T, Neven P, Serteyn D, Art T.No abstract available
Multiple small-intestine intussusceptions: a complication of purpura haemorrhagica in a horse.
Tijdschrift voor diergeneeskunde    June 28, 2011   Volume 136, Issue 6 422-426 
Dujardin CL.A Belgian draft horse stallion presented with classical signs of purpura haemorrhagica: oedema of the distal limbs, ventral abdomen and head, ecchymotic haemorrhage of mucous membranes, epistaxis, fever, lethargy, reluctance to move, and anorexia. Serum chemistry revealed a highly elevated gamma-globulin fraction. Streptococcal lymphadenitis (strangles) had been present on a neighbouring farm in the past few months. After an initial positive response to therapy with benzylpenicillin, flunixin and dexamethasone, the horse's condition deteriorated suddenly on day 4 of hospitalization, with signs...
Diagnostic and epidemiologic analysis of the 2008-2010 investigation of a multi-year outbreak of contagious equine metritis in the United States.
Preventive veterinary medicine    June 28, 2011   Volume 101, Issue 3-4 219-228 doi: 10.1016/j.prevetmed.2011.05.015
Erdman MM, Creekmore LH, Fox PE, Pelzel AM, Porter-Spalding BA, Aalsburg AM, Cox LK, Morningstar-Shaw BR, Crom RL.Contagious equine metritis (CEM) is a highly contagious venereal disease of horses caused by Taylorella equigenitalis. During testing for semen export purposes, a stallion in Kentucky was found to be T. equigenitalis culture positive in December of 2008. This finding triggered an extensive regulatory investigation to search for additional positive horses, determine the extent of the outbreak, identify the potential source of the outbreak, and ultimately return the United States to CEM-free status. The investigation included over 1000 horses located in 48 states. Diagnostic testing found a tota...
Magnetic resonance imaging in foals with infectious arthritis. Gaschen L, LeRoux A, Trichel J, Riggs L, Bragulla HH, Rademacher N, Rodriguez D.The magnetic resonance (MR) imaging findings of foals with infectious and noninfectious arthritis are described. Six foals with infectious arthritis and three foals with noninfectious arthritis were grouped based on synovial fluid analysis results and examined with radiography and MR imaging. Four out of six foals with infectious arthritis had osseous lesions in MR images indicative of osteomyelitis and only 4/19 lesions were detected on digital radiographs. The three foals with noninfectious arthritis had no osseous lesions in MR images or radiographically. Of the six joints that had osseous ...
Molecular diagnostics of leptospirosis in horses is becoming increasingly important.
Veterinary microbiology    June 28, 2011   Volume 153, Issue 3-4 413 doi: 10.1016/j.vetmic.2011.06.015
Pinna AE, Martins G, Hamond C, Lilenbaum W, Medeiros MA.No abstract available
[Are parasite egg counts in horses repeatable?].
Tijdschrift voor diergeneeskunde    June 28, 2011   Volume 136, Issue 6 428-429 
Tijms JH, Sloet van Oldruitenborgh-Oosterbaan MM, Ploeger HW, van Doorn DC.No abstract available
Infection of peripheral blood mononuclear cells with neuropathogenic equine herpesvirus type-1 strain Ab4 reveals intact interferon-α induction and induces suppression of anti-inflammatory interleukin-10 responses in comparison to other viral strains.
Veterinary immunology and immunopathology    June 28, 2011   Volume 143, Issue 1-2 116-124 doi: 10.1016/j.vetimm.2011.06.032
Wagner B, Wimer C, Freer H, Osterrieder N, Erb HN.The recent increase in incidence, morbidity, and mortality of neurological disease induced by equine herpesvirus type 1 (EHV-1) has suggested a change of virulence of the virus. The exact mechanisms by which EHV-1 induces neurologic disease are not known. Environmental, viral, and host risk factors might contribute to neurological manifestation. Here, we investigated innate interferon-α (IFN-α), interleukin-10 (IL-10) and IL-4 responses after infection of equine peripheral blood mononuclear cells (PBMC) with EHV-1 using an available cytokine multiplex assay. Three viral strains representing ...
The effect of environment on interferon-gamma production in neonatal foals.
Veterinary immunology and immunopathology    June 28, 2011   Volume 143, Issue 1-2 170-175 doi: 10.1016/j.vetimm.2011.06.030
Sun L, Adams AA, Page AE, Betancourt A, Horohov DW.While interferon-gamma (IFNγ) plays an important role in protection against viral and intracellular bacterial infections, its production in neonates is deficient. Exposure to environmental antigens can promote the maturation of the immune system of neonatal humans and mice. We hypothesize that exposure to high level of microbial components would increase the production of IFNγ in neonatal foals. To test this hypothesis, one group of foals was placed into stalls three times a week for 8 weeks. A second group of foals remained on pasture. Air samples were collected from the barn and pasture fo...
Seroprevalence of Streptococcus equi in working horses in Lesotho.
The Veterinary record    June 27, 2011   Volume 169, Issue 3 72 doi: 10.1136/vr.d1725
Ling AS, Upjohn MM, Webb K, Waller AS, Verheyen KL.No abstract available
Comparison of different liquid chromatography stationary phases in LC-HRMS metabolomics for the detection of recombinant growth hormone doping control.
Journal of separation science    June 27, 2011   Volume 34, Issue 24 3493-3501 doi: 10.1002/jssc.201100223
Boyard-Kieken F, Dervilly-Pinel G, Garcia P, Paris AC, Popot MA, le Bizec B, Bonnaire Y.Growth hormone (GH) is a polypeptide suspected of being used in horse racing to speed up physical performances. Despite scientific advances in the recent years, the control of its administration remains difficult. In order to improve it, a metabolomics study through LC-high resolution mass spectrometry measurements was recently initiated to assess the metabolic perturbations caused by recombinant equine growth hormone administration. Few tens of ions not identified structurally were highlighted as compounds responsible for the modification of metabolic profiling observed in treated animals. Th...
Effects of cutting frequency and height on alkaloid production in endophyte-infected drunken horse grass (Achnatherum inebrians).
Science China. Life sciences    June 26, 2011   Volume 54, Issue 6 567-571 doi: 10.1007/s11427-011-4181-y
Zhang X, Li C, Nan Z.An evaluation was performed on the influence of mowing height (2.5, 5.0 or 7.5 cm) and mowing frequency (weekly or fortnightly) on levels of ergot alkaloids (ergine and ergonovine) formed in drunken horse grass, Achnatherum inebrians, grown under greenhouse conditions. Samples were taken monthly and alkaloids were extracted and analyzed by reverse-phase HPLC. Alkaloid levels increased more or less linearly with plant age over the first four months following establishment. Levels were higher in samples cut fortnightly compared to those cut weekly, and were higher when plants were cut at a mowin...
Acute myeloid leukaemia (M6B: pure acute erythroid leukaemia) in a Thoroughbred foal.
Australian veterinary journal    June 24, 2011   Volume 89, Issue 7 269-272 doi: 10.1111/j.1751-0813.2011.00790.x
Forbes G, Feary DJ, Savage CJ, Nath L, Church S, Lording P.A 10-week-old Thoroughbred filly was referred for anaemia of 4 weeks' duration. Haematology revealed severe anaemia and panleucopenia. Cytological examination of bone marrow smears revealed a myeloid to erythroid ratio <0.02:1 (reference range 0.5-2.4:1.0) and an abundance of erythroid precursor cells. The erythroid cell population included rubriblasts, prorubricytes and rubricytes, with only scant numbers of metarubricytes present. There were numerous mitotic erythroid cells, some of which were atypical and megaloblastic. These cytomorphological changes are consistent with pure acute eryth...
Retrospective study of outcome following desmotomy of the accessory ligament of the deep digital flexor tendon for type 1 flexural deformity in Thoroughbreds.
Australian veterinary journal    June 24, 2011   Volume 89, Issue 7 265-268 doi: 10.1111/j.1751-0813.2011.00788.x
Walmsley EA, Anderson GA, Adkins AR.Determine the long-term outcome for Thoroughbreds undergoing desmotomy of the accessory ligament of the deep digital flexor tendon (DAL-DDFT) for type 1 flexural deformity of the distal interphalangeal joint (DIPJ). Methods: Retrospective matched cohort study Methods: Medical records were retrieved over a 17-year period for Thoroughbreds that underwent DAL-DDFT for type 1 flexural deformity. Long-term outcome was determined by analysis of race records and comparison with maternal siblings. Comparisons between cases and controls included 2-year-old, 3-year-old and total career performance data....
Identification of risk factors for traumatic injury in the general horse population of north-west England, Midlands and north Wales.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 2 143-148 doi: 10.1111/j.2042-3306.2011.00387.x
Owen KR, Singer ER, Clegg PD, Ireland JL, Pinchbeck GL.Traumatic injuries are a major cause of morbidity and mortality in the horse and consequently pose a serious threat to horses' wellbeing. To date, there have been no published studies assessing the frequency of injuries in the general horse population of the UK. Objective: To obtain information regarding husbandry management strategies and injury prevalence in horses aged ≤15 years, with the aim of identifying predisposing risk factors for injury. Methods: A postal questionnaire was distributed to a randomly selected sample of horse owners across north-west England, Midlands and north Wales....
The timeline of metalloprotease events during oligofructose induced equine laminitis development.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 1 88-93 doi: 10.1111/j.2042-3306.2011.00393.x
Visser MB, Pollitt CC.The role of matrix metalloproteases (MMPs) and the timeline of proteolysis during laminitis development are incompletely understood. Objective: To determine the temporal progression of selected MMPs and protease regulators during laminitis development. Methods: Five clinically normal Standardbred horses received, via nasogastric intubation, an oligofructose (OF) bolus (10 g/kg bwt). Laminitis induction proceeded for 48 h followed by euthanasia. Lamellar biopsies were obtained prior to dosing and at intervals during the treatment period for analysis (12, 18, 24, 30 and 36 h and at 48 h followin...
Phacoemulsification and implantation of foldable +14 diopter intraocular lenses in five mature horses.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 2 238-243 doi: 10.1111/j.2042-3306.2011.00392.x
Townsend WM, Jacobi S, Bartoe JT.Presently, intraocular lenses (IOLs) are not routinely implanted after equine cataract surgery. Subsequently, horses are visual but markedly farsighted (hyperopic). This report describes the surgical results and visual status after phacoemulsification and implantation of IOLs in mature horses with spontaneous cataracts. Six eyes of 5 mature horses underwent phacoemulsification and implantation of a +14 diopter (D) foldable IOL. Recheck ocular examinations were performed at 1, 4 and 24 weeks post operatively. Refractive error was recorded at 4 weeks post operatively. Visual status, refractive e...
Serum concentration of surfactant protein D in horses with lower airway inflammation.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 3 277-281 doi: 10.1111/j.2042-3306.2011.00421.x
Richard EA, Pitel PH, Christmann U, Lekeux P, Fortier G, Pronost S.Surfactant protein D (SP-D), mainly synthesised by alveolar type II cells and nonciliated bronchiolar cells, is one important component of innate pulmonary immunity. In man, circulating concentrations of SP-D are routinely used as biomarkers for pulmonary injury. To date, serum SP-D levels have only been investigated in horses in an experimental model of bacterial airway infection. Objective: To compare serum SP-D concentrations at rest and after exercise in horses with and without inflammatory airway disease (IAD). Methods: Venous blood samples were collected from 42 Standardbred racehorses a...
Association of Streptococcus equi with equine monocytes.
Veterinary immunology and immunopathology    June 23, 2011   Volume 143, Issue 1-2 83-86 doi: 10.1016/j.vetimm.2011.06.027
Mérant C, Sheoran A, Timoney JF.Streptococcus equi (Se), the cause of equine strangles, is highly resistant to phagocytosis by neutrophils and is usually classified as an extracellular pathogen. Large numbers of the organism in tonsillar tissues during the acute phase of the disease are completely eliminated during convalescence by mechanisms not yet understood. In this study we demonstrate in an opsono-bactericidal assay and by cytometry and confocal microscopy that Se is interiorized and killed by equine blood monocytes. This finding supports the hypotheses that adaptive immune clearance is mediated by tonsillar macrophage...
Cervical vertebral canal endoscopy in a horse with cervical vertebral stenotic myelopathy.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 1 116-119 doi: 10.1111/j.2042-3306.2011.00395.x
Prange T, Carr EA, Stick JA, Garcia-Pereira FL, Patterson JS, Derksen FJ.A 3-year-old Thoroughbred gelding presented with a history of neurological signs, including incoordination in his hindlimbs, of about 7 months' duration. On initial examination, the horse exhibited ataxia and paresis in all limbs with more severe deficits in the hindlimbs. Cervical radiographs displayed severe osteoarthritis of the articular processes between C5 and C6. On subsequent cervical myelography the dorsal contrast column was reduced by 90% at the level of the intervertebral space between C5 and C6. Cervical vertebral canal endoscopy, including epidural (epiduroscopy) and subarachnoid...
A novel treatment for dynamic laryngeal collapse associated with poll flexion: the modified checkrein.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 2 207-213 doi: 10.1111/j.2042-3306.2011.00388.x
Fjordbakk CT, Holcombe S, Fintl C, Chalmers H, Strand E.Dynamic laryngeal collapse (DLC) associated with poll flexion is a performance limiting dynamic upper airway disorder commonly diagnosed in Coldblooded trotters. An inspiratory obstruction occurs when affected horses are driven with tension on the reins, inducing poll flexion. To date, surgical treatment and conservative management have failed to improve racing performance in affected horses. Objective: To test the efficacy of an external device, the modified checkrein, in limiting poll flexion, diminishing laryngeal collapse and improving airway mechanics when horses are driven on a treadmill...
Comparisons of computed tomography, contrast-enhanced computed tomography and standing low-field magnetic resonance imaging in horses with lameness localised to the foot. Part 2: Lesion identification.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 2 149-156 doi: 10.1111/j.2042-3306.2011.00386.x
Vallance SA, Bell RJ, Spriet M, Kass PH, Puchalski SM.No previous study compares computed tomography (CT), contrast-enhanced computed tomography (CECT) and standing low-field magnetic resonance imaging (LFMRI) to detect lesions in horses with lameness localised to the foot. This study will help clinicians understand the limitations of these techniques. Objective: To determine if CT, CECT and LFMRI would identify lesions within the distal limb and document discrepancies with lesion distribution and lesion classification. Methods: Lesions in specific structures identified on CT and MR images of feet (31 limbs) from the same horse were reviewed and ...
Comparison of owner-reported health problems with veterinary assessment of geriatric horses in the United Kingdom.
Equine veterinary journal    June 23, 2011   Volume 44, Issue 1 94-100 doi: 10.1111/j.2042-3306.2011.00394.x
Ireland JL, Clegg PD, McGowan CM, McKane SA, Chandler KJ, Pinchbeck GL.Previous studies suggest that owners underestimate or incorrectly recognise or report health problems in geriatric horses. However, few studies have directly compared owner-reported and veterinary assessed disease. Objective: To compare the findings of veterinary clinical examination of geriatric horses with owner-reported clinical signs and disease. Methods: A total of 200 horses aged ≥ 15 years were randomly selected to receive a veterinary examination, from responses to a cross-sectional postal questionnaire survey. Veterinary examinations were performed within 2 months of questionnaire r...