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Topic:Equine Health

Equine health encompasses the study and management of diseases, disorders, and overall well-being of horses. It involves understanding various physiological systems, preventive care, and treatment strategies to maintain optimal health in equine populations. Common areas of focus include nutrition, infectious diseases, orthopedic conditions, and reproductive health. Research in equine health aims to advance knowledge on diagnostic methods, therapeutic interventions, and management practices that improve horse welfare and performance. This page collects peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine health, offering insights into current findings and advancements in the field.
Auricular chondrosis in a horse.
Australian veterinary journal    June 6, 2009   Volume 87, Issue 6 219-221 doi: 10.1111/j.1751-0813.2009.00427.x
Bowers JR, Slocombe RF.A 4-year-old crossbred, Welsh Mountain Pony gelding was presented with multiple, thick, round, raised, 3 to 8 mm diameter nodular lesions on the medial aspects of both ears. The nodules did not involve the epidermis and were observed to develop over several months. Punch biopsies were taken and histopathological examination returned a diagnosis of auricular chondrosis. Neither auricular chondrosis nor auricular chondritis has been reported in horses, although it has been recorded in cats, dogs, laboratory animals and humans.
Alternative solution of virtual biomodeling based on CT-scans.
Journal of biomechanics    June 5, 2009   Volume 42, Issue 12 2006-2009 doi: 10.1016/j.jbiomech.2009.05.007
Groesel M, Gfoehler M, Peham C.In this paper, an alternative method is presented to convert computed tomography (CT)-scans into 3D biomodels. The CT-data of an equine spine was converted into TIF format to work with it in a 2D CAD program. Then the bony structure has been marked manually with closed splines and saved as IGS files for the next procedure with 3D CAD software to create virtual biomodels of every single bone. Therefore, the different layers of the CT-scans were positioned in correct distance and then a closed surface was created to cover all spline-curves. Finally, the cover was filled up with material to creat...
Role of the hypoglossal nerve in equine nasopharyngeal stability.
Journal of applied physiology (Bethesda, Md. : 1985)    June 4, 2009   Volume 107, Issue 2 471-477 doi: 10.1152/japplphysiol.91177.2008
Cheetham J, Pigott JH, Hermanson JW, Campoy L, Soderholm LV, Thorson LM, Ducharme NG.The equine upper airway is highly adapted to provide the extremely high oxygen demand associated with strenuous aerobic exercise in this species. The tongue musculature, innervated by the hypoglossal nerve, plays an important role in airway stability in humans who also have a highly adapted upper airway to allow speech. The role of the hypoglossal nerve in stabilizing the equine upper airway has not been established. Isolated tongues from eight mature horses were dissected to determine the distal anatomy and branching of the equine hypoglossal nerve. Using this information, a peripheral nerve ...
Overtrained horses alter their resting pulsatile growth hormone secretion.
American journal of physiology. Regulatory, integrative and comparative physiology    June 3, 2009   Volume 297, Issue 2 R403-R411 doi: 10.1152/ajpregu.90778.2008
de Graaf-Roelfsema E, Veldhuis PP, Keizer HA, van Ginneken MM, van Dam KG, Johnson ML, Barneveld A, Menheere PP, van Breda E, Wijnberg ID....The influence of intensified and reduced training on nocturnal growth hormone (GH) secretion and elimination dynamics was studied in young (1.5 yr) Standardbred geldings to detect potential markers indicative for early overtraining. Ten horses trained on a treadmill for 32 wk in age-, breed-, and gender-matched fixed pairs. Training was divided into four phases (4, 18, 6, and 4 wk, respectively): 1) habituation to high-speed treadmill trotting, 2) normal training, in which speed and duration of training sessions were gradually increased, 3) in this phase, the horses were divided into 2 groups:...
Fine mapping a quantitative trait locus on horse chromosome 2 associated with radiological signs of navicular disease in Hanoverian warmblood horses.
Animal genetics    June 3, 2009   Volume 40, Issue 6 955-957 doi: 10.1111/j.1365-2052.2009.01923.x
Lopes MS, Diesterbeck U, da Câmara Machado A, Distl O.Navicular disease or podotrochlosis is one of the main causes of progressive forelimb lameness in warmblood horses. The objective of this study was to refine a quantitative trait locus on horse chromosome 2 for radiological alterations in the contour of the navicular bone (RAC) in Hanoverian warmblood horses. Genotyping was performed in 192 Hanoverian warmblood horses from 17 paternal half-sib groups. The marker set was extended to 58 informative microsatellites including nine newly developed microsatellites. QTL for RAC could be delineated at 32.50-43.13 Mb and a further new QTL for RAC could...
Progesterone responses to intravenous and intrauterine infusions of prostaglandin F2alpha in mares.
Reproduction, fertility, and development    June 3, 2009   Volume 21, Issue 5 688-695 doi: 10.1071/RD09019
Ginther OJ, Siddiqui MA, Beg MA.The hypotheses were tested that prostaglandin F2alpha (PGF) travels from the uterus to the ovaries via a systemic route in mares, as opposed to a local route in ruminants, and that one pulse of PGF produces only partial luteolysis. Intravenous (i.v.) and intrauterine (i.u.) infusions of PGF were performed 8 days after ovulation at a constant rate for 2 h. Plasma concentrations of PGF were assessed by assay of 13,14-dihydro-15-keto-PGF2alpha (PGFM). Total doses administered were as follows: 0, 0.05, 0.1, 0.5 and 1.0 mg, i.v., PGF and 0 and 0.5 mg, i.u., PGF (n=4 mares per group). In addition, P...
The extracellular calcium-sensing receptor is expressed in the cumulus-oocyte complex in mammals and modulates oocyte meiotic maturation.
Reproduction (Cambridge, England)    June 3, 2009   Volume 138, Issue 3 439-452 doi: 10.1530/REP-09-0078
De Santis T, Casavola V, Reshkin SJ, Guerra L, Ambruosi B, Fiandanese N, Dalbies-Tran R, Goudet G, Dell'Aquila ME.The extracellular calcium-sensing receptor (CASR) plays an important role in cells involved in calcium (Ca2+) homeostasis by directly sensing changes in the extracellular Ca2+ ion concentration. We previously reported the localization and quantitative expression of CASR protein in human oocytes. In this study, we examined the expression and the functional role of CASR during oocyte meiotic maturation in a large mammal animal model, the horse. As in humans, CASR protein was found to be expressed in equine oocytes and cumulus cells. Western-blot analysis revealed a single 130 kDa band in denuded...
Follicle suppression of circulating follicle-stimulating hormone and luteinizing hormone before versus after emergence of the ovulatory wave in mares.
Theriogenology    June 3, 2009   Volume 72, Issue 4 445-452 doi: 10.1016/j.theriogenology.2009.03.012
Ginther OJ, Gastal EL, Gastal MO, Duarte LF, Beg MA.The effect of the ovarian follicles on plasma concentrations of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) before versus after the expected emergence of the ovulatory follicular wave was studied on Days 0 to 18 (Day 0=ovulation) in four groups of mares (n=6/group). In addition to a control group, all follicles >/=6mm in diameter were ablated on Days 0.5, 6.5, or 12.5 in a herd of mares with reported emergence at 6mm of the future ovulatory follicle on mean Day 10.5. Concentrations of FSH were not different between the Day-0.5 or Day-6.5 ablation groups and the correspon...
Tendinitis of the proximal aspect of the superficial digital flexor tendon in horses: 12 cases (2000-2006).
Journal of the American Veterinary Medical Association    June 2, 2009   Volume 234, Issue 11 1432-1436 doi: 10.2460/javma.234.11.1432
Chesen AB, Dabareiner RM, Chaffin MK, Carter GK.To determine clinical signs, ultrasonographic findings, and outcome of horses with tendinitis of the proximal portion of the superficial digital flexor tendon (SDFT; group A horses) and to compare signalment, horse use, and outcome in these horses with that of horses with tendinitis of the midmetacarpal region of the SDFT (group B horses). Methods: Retrospective case series. Methods: 12 group A horses and 22 group B horses. Methods: Medical records were reviewed for signalment, horse use, and outcome information; data for group A horses also included severity of lameness, diagnostic results, a...
A genome scan for positive selection in thoroughbred horses.
PloS one    June 2, 2009   Volume 4, Issue 6 e5767 doi: 10.1371/journal.pone.0005767
Gu J, Orr N, Park SD, Katz LM, Sulimova G, MacHugh DE, Hill EW.Thoroughbred horses have been selected for exceptional racing performance resulting in system-wide structural and functional adaptations contributing to elite athletic phenotypes. Because selection has been recent and intense in a closed population that stems from a small number of founder animals Thoroughbreds represent a unique population within which to identify genomic contributions to exercise-related traits. Employing a population genetics-based hitchhiking mapping approach we performed a genome scan using 394 autosomal and X chromosome microsatellite loci and identified positively selec...
Your racing horses will help you to quit: a lesson for COPD and alpha1-antitrypsin deficiency research.
The European respiratory journal    June 2, 2009   Volume 33, Issue 6 1244-1246 doi: 10.1183/09031936.00026409
Soriano JB, Miravitlles M.No abstract available
[Endocrine and behavioral changes as a consequence of stress in horses].
Tijdschrift voor diergeneeskunde    June 2, 2009   Volume 134, Issue 9 388-390 
de Graaf-Roelfsema E.No abstract available
Anthelmintic efficacies of a tablet formula of ivermectin-praziquantel on horses experimentally infected with three Strongylus species.
Parasitology research    June 2, 2009   Volume 105, Issue 3 817-823 doi: 10.1007/s00436-009-1460-7
Bonneau S, Maynard L, Tomczuk K, Kok D, Eun HM.In this blinded randomized and controlled study, the anthelmintic efficacy of a tablet formula of ivermectin-praziquantel was evaluated in horses experimentally infected with three species of Strongylus larvae. Eighteen previously dewormed horses were inoculated on study day 0 with third-stage larvae of Strongylus vulgaris, Strongylus equinus, and Strongylus edentatus. The horses were randomly allocated to three groups (n = 6): test-drug (tablet formula), positive-control (reference gel), and negative-control (placebo tablet). On day 56, the horses were treated once with the respective drugs. ...
Nutritional management of laminitis in a horse.
The Veterinary record    June 2, 2009   Volume 164, Issue 22 694-695 doi: 10.1136/vr.164.22.694
Van Weyenberg S, Hesta M, Kalmar ID, Vandermeiren J, Janssens GP.No abstract available
Left ventricular radial and circumferential wall motion analysis in horses using strain, strain rate, and displacement by 2D speckle tracking.
Journal of veterinary internal medicine    June 1, 2009   Volume 23, Issue 4 890-900 doi: 10.1111/j.1939-1676.2009.0321.x
Schwarzwald CC, Schober KE, Berli AS, Bonagura JD.Noninvasive assessment of left-ventricular (LV) function is clinically relevant, but is incompletely studied in horses. Objective: To document the feasibility, describe the techniques, and determine the reliability of 2D speckle tracking (2DST) for characterization of LV radial and circumferential wall motion in horses. Methods: Three Standardbreds, 3 Thoroughbreds; age 8-14 years; body weight 517-606 kg. Methods: Observational study. Repeated 2-dimensional echocardiographic examinations were performed in unsedated horses by 2 observers and subsequently analyzed by 2DST. Test reliability was d...
Hypothalamic-pituitary-adrenal axis dysfunction in hospitalized neonatal foals.
Journal of veterinary internal medicine    June 1, 2009   Volume 23, Issue 4 901-912 doi: 10.1111/j.1939-1676.2009.0323.x
Hart KA, Slovis NM, Barton MH.Transient hypothalamic-pituitary-adrenal (HPA) axis dysfunction occurs frequently in critically ill humans and impacts survival. The prevalence and impact of HPA axis dysfunction in critically ill neonatal foals are not well characterized. Objective: (1) HPA axis dysfunction occurs in hospitalized neonatal foals, and is characterized by inappropriately low basal serum cortisol concentration or inadequate cortisol response to exogenous adrenocorticotropic hormone (ACTH); (2) hospitalized foals with HPA axis dysfunction have more severe disease and are less likely to survive than hospitalized fo...
Incidence of animal poisoning cases in the Czech Republic: current situation.
Interdisciplinary toxicology    June 1, 2009   Volume 2, Issue 2 48-51 doi: 10.2478/v10102-009-0009-z
Modrá H, Svobodová Z.This article reports the most frequent cases of poisoning in farm animals, horses, cats, dogs, wild animals, fish and honey-bees in the Czech Republic. At present, there are fewer cases of acute poisoning caused by high doses of toxic substances but there are more and more cases of chronic poisoning as a consequence of environmental pollution.
Body mass index and serum gamma-glutamyltransferase level as risk factors for injuries related to professional horse racing: a prospective study.
Journal of occupational health    June 1, 2009   Volume 51, Issue 4 323-331 doi: 10.1539/joh.l8158
Tobari H, Yamagishi K, Noda H, Tanigawa T, Iso H.Prevention of horse-related injuries is considered difficult because horse behavior is unpredictable. Therefore, risk factors for injuries related to professional horse racing need to be investigated. We conducted a study to determine whether body mass index (BMI) and gamma-glutamyltransferase (GGT) levels are associated with professional horse racing-related injuries. Methods: A baseline healthy survey of 546 male grooms and exercise riders aged 40-70 yr working at Miho Training Center, the largest racing-horse training facility in Japan, was performed in May 2003. A total of 93 occupational ...
Control of Bovicola equi (Phthiraptera: Trichodectidae) with Dimilin and permethrin.
Journal of vector ecology : journal of the Society for Vector Ecology    June 1, 2009   Volume 34, Issue 1 160 doi: 10.1111/j.1948-7134.2009.00021.x
Reeves WK, Miller MM.No abstract available
Protective immunization of horses with a recombinant canarypox virus vectored vaccine co-expressing genes encoding the outer capsid proteins of African horse sickness virus.
Vaccine    May 31, 2009   Volume 27, Issue 33 4434-4438 doi: 10.1016/j.vaccine.2009.05.044
Guthrie AJ, Quan M, Lourens CW, Audonnet JC, Minke JM, Yao J, He L, Nordgren R, Gardner IA, Maclachlan NJ.We describe the development and preliminary characterization of a recombinant canarypox virus vectored (ALVAC) vaccine for protective immunization of equids against African horse sickness virus (AHSV) infection. Horses (n=8) immunized with either of two concentrations of recombinant canarypox virus vector (ALVAC-AHSV) co-expressing synthetic genes encoding the outer capsid proteins (VP2 and VP5) of AHSV serotype 4 (AHSV-4) developed variable titres (<10-80) of virus-specific neutralizing antibodies and were completely resistant to challenge infection with a virulent strain of AHSV-4. In contra...
Immunisation of the equine uterus against Streptococcus equi subspecies zooepidemicus using an intranasal attenuated Salmonella vector.
Veterinary journal (London, England : 1997)    May 30, 2009   Volume 184, Issue 2 156-161 doi: 10.1016/j.tvjl.2009.05.001
Causey RC, Artiushin SC, Crowley IF, Weber JA, Homola AD, Kelley A, Stephenson LA, Opitz HM, Guilmain S, Timoney JF.Attenuated Salmonella enterica serovar Typhimurium MGN707, expressing the SzP protective protein of the MB9 serovar of Streptococcus equi subspecies zooepidemicus (SzP-MB9) was tested for its safety and efficacy as a nebulised intranasal vaccine against streptococcal uterine infections in mares. In a preliminary study, vaccinated mares (n=5) displayed serum, nasal and uterine responses (P<0.05) to S. Typhimurium lipopolysaccharide (St-LPS). Subsequently, vaccinated mares (expressor group, n=7), but not mares vaccinated with the vector only (control group, n=7), displayed significant increas...
A retrospective analysis of renal carcinoma in the horse.
Journal of veterinary internal medicine    May 30, 2009   Volume 23, Issue 4 913-918 doi: 10.1111/j.1939-1676.2009.0326.x
Wise LN, Bryan JN, Sellon DC, Hines MT, Ramsay J, Seino KK.Renal carcinoma is a rare tumor of horses. Objective: Presenting complaints and clinical signs of this disease are vague and early diagnosis increases survival time. Methods: Data were collected from the medical records of 4 horses presented to Washington State University as well as the 23 previously published case reports of horses with renal carcinoma. Methods: Retrospective study. Results: Renal carcinoma affects horses of all ages with most cases observed in geldings and Thoroughbreds. The most common presenting complaints are nonspecific and usually do not occur until late in the course o...
Risk of equine infectious anemia virus disease transmission through in vitro embryo production using somatic cell nuclear transfer.
Theriogenology    May 30, 2009   Volume 72, Issue 3 289-299 doi: 10.1016/j.theriogenology.2009.03.009
Gregg K, Polejaeva I.Prevention and regulation of equine infectious anemia virus (EIAV) disease transmission solely depend on identification, isolation, and elimination of infected animals because of lack of an effective vaccine. Embryo production via the somatic cell nuclear transfer (SCNT) technology uses oocytes collected mainly from untested animals, which creates a potential risk of EIAV transmission through infected embryos. The current review examines the risk of EIAV disease transmission through SCNT embryo production and transfer. Equine infectious anemia virus is a lentivirus from the family Retroviridae...
Dimensions of diastemata and associated periodontal food pockets in donkey cheek teeth.
Journal of veterinary dentistry    May 30, 2009   Volume 26, Issue 1 10-14 doi: 10.1177/089875640902600105
Du Toit N, Burden FA, Baedt LG, Shaw DJ, Dixon PM.Equine cheek teeth (CT) diastemata often cause deep periodontal food pocketing and are therefore regarded as a painful dental disorder of equidae. However there appears to be no information available on the size or shape of these diastemata. This post mortem study examined 16 donkey skulls (mean age = 32-years) containing 45 CT diastemata to define the anatomical shape and dimensions of these diastemata, and of the associated periodontal food pockets that occur with this disorder. Diastemata were found to more commonly involve mandibular (56.0%) compared with maxillary CT (44.0%), and 71.0% of...
Assessment of pregnancy in the late-gestation mare using digital infrared thermography.
Theriogenology    May 30, 2009   Volume 72, Issue 3 372-377 doi: 10.1016/j.theriogenology.2009.03.005
Bowers S, Gandy S, Anderson B, Ryan P, Willard S.The objective of this study was to investigate use of digital infrared thermal imaging (DITI) to determine whether surface temperature gradient differences exist between pregnant and nonpregnant mares as a noncontact method to determine pregnancy status. On the day measurements were collected, each pregnant mare (n=10; beginning at 292.4+/-1.4 d of gestation) was paired with a nonpregnant mare (n=17). Ambient temperature, DITI measurements (left and right flank, wither temperatures [i.e., animal surface control] and background temperature), and rectal temperatures were obtained every 7 d for 5...
Laboratory findings in respiratory fluids of the poorly-performing horse.
Veterinary journal (London, England : 1997)    May 29, 2009   Volume 185, Issue 2 115-122 doi: 10.1016/j.tvjl.2009.05.003
Richard EA, Fortier GD, Lekeux PM, Van Erck E.Any disorder impairing a performance horse's ability to ventilate its lungs and exchange oxygen compromises exercise performance in any discipline. Since bronchoalveolar lavage was described in horses in the early 1980s, laboratory evaluation of respiratory fluids, along with clinical and functional assessment of the respiratory system, has become a relevant step in the diagnosis of respiratory disease affecting performance. The aim of this review is to provide objective information to assist clinicians in interpreting laboratory findings by (1) summarising published cytological references val...
Mechanical recovery of inhibited cyathostomin larvae from equine intestinal tissue.
Parasitology research    May 29, 2009   Volume 105, Issue 2 587-589 doi: 10.1007/s00436-009-1473-2
Glover ID, Henry GM, Townsend NB, Coles GC.The Stomacher is very widely used in food and medical research for extracting tissues. To determine whether nematode larvae were disrupted by the Stomacher, L3 larvae of Haemonchus contortus were homogenised for up to 40 min at full power but no larval disruption occurred. Therefore, tissue from the mucosa and submucosa of the caecum of horses collected from a licenced abattoir was treated to determine whether inhibited cyathostomin larvae could be extracted. The optimum time on full power for a 10-g sample was 20 min, and in three out of five caecal samples from different horses, significantl...
The effect of different head and neck positions on the caudal back and hindlimb kinematics in the elite dressage horse at trot.
Equine veterinary journal    May 28, 2009   Volume 41, Issue 3 274-279 doi: 10.2746/042516409x394436
Rhodin M, Gómez Alvarez CB, Byström A, Johnston C, van Weeren PR, Roepstorff L, Weishaupt MA.Dressage involves training of the horse with the head and neck placed in a position defined by the rider. The best position for dressage training is currently under debate among riders and trainers, but there are few scientific data available to confirm or disprove the different views. Objective: To evaluate the kinematic effects of different head and neck positions (HNPs) in elite dressage horses ridden at trot. Methods: Seven high-level dressage horses were subjected to kinetic and kinematic measurements when ridden on a treadmill with the head and neck in 5 different positions. Results: Com...
Evaluation of discriminant analysis based on dorsoventral symmetry indices to quantify hindlimb lameness during over ground locomotion in the horse.
Equine veterinary journal    May 28, 2009   Volume 41, Issue 3 304-308 doi: 10.2746/042516409x397352
Church EE, Walker AM, Wilson AM, Pfau T.Advances in gait analysis techniques have led to assessment tools that can aid in detecting and quantifying lameness; here, bilateral tubera coxae and pelvic movement during over ground locomotion are compared in order to investigate a practical method to assess hindlimb lameness in the horse. Objective: To evaluate which parameters from anatomical landmarks on trunk and proximal hindlimbs are the best indicators of degree and side of hindlimb lameness. Methods: Fifteen horses (age 11-23 years, 6 nonlame and 9 unilaterally hindlimb lame horses 1/10 to 2/10 lame) were fitted with 4 inertial sen...
The relationship between range of motion of lumbosacral flexion-extension and canter velocity of horses on a treadmill.
Equine veterinary journal    May 28, 2009   Volume 41, Issue 3 301-303 doi: 10.2746/042516409x397271
Johnson JL, Moore-Colyer M.Research into kinematics of the healthy equine back, has been performed in the walk and trot. This study focuses on back kinematics during canter, over a range of velocities. Flexion extension (FE) movements in canter are greatest in the lumbosacral (LS) region. Previous research has focused on canter velocity of 7 m/s; therefore quantification of LS kinematics at varying velocities is required to understand LS functions in equine locomotion. Objective: Range of flexion-extension movement through the lumbosacral joint increases with increasing velocity. Methods: Six Thoroughbred horses (mean a...