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Topic:Equine Science

Equine Science encompasses the study of horses and their management, health, and performance. This field integrates various scientific disciplines such as biology, genetics, nutrition, physiology, and veterinary medicine to understand and improve the well-being and capabilities of horses. Areas of focus include equine anatomy, reproduction, behavior, and disease prevention. Research in equine science aims to enhance horse care, optimize training and performance, and address health challenges. This page compiles peer-reviewed research studies and scholarly articles that explore the diverse aspects of equine science, providing insights into the latest advancements and methodologies in the field.
Why doesn’t conventional IVF work in the horse? The equine oviduct as a microenvironment for capacitation/fertilization.
Reproduction (Cambridge, England)    September 20, 2016   Volume 152, Issue 6 R233-R245 doi: 10.1530/REP-16-0420
Leemans B, Gadella BM, Stout TA, De Schauwer C, Nelis H, Hoogewijs M, Van Soom A.In contrast to man and many other mammalian species, conventional in vitro fertilization (IVF) with horse gametes is not reliably successful. The apparent inability of stallion spermatozoa to penetrate the zona pellucida in vitro is most likely due to incomplete activation of spermatozoa (capacitation) because of inadequate capacitating or fertilizing media. In vivo, the oviduct and its secretions provide a microenvironment that does reliably support and regulate interaction between the gametes. This review focuses on equine sperm-oviduct interaction. Equine sperm-oviduct binding appears to be...
Horses give functionally relevant responses to human facial expressions of emotion: a response to Schmoll (2016).
Biology letters    September 15, 2016   Volume 12, Issue 9 20160549 doi: 10.1098/rsbl.2016.0549
Smith AV, Proops L, Grounds K, Wathan J, McComb K.No abstract available
Detection of single nucleotide polymorphisms (SNP) in equine coat color genes using SNaPshotTM multiplex kit or pluronic F-108 tri-block copolymer and capillary electrophoresis.
Electrophoresis    September 12, 2016   Volume 37, Issue 21 2862-2866 doi: 10.1002/elps.201600245
Martin L, Damaso N, Mills D.Molecular methods for the detection of mammalian coat color phenotypes have expanded greatly within the past decade. Many phenotypes are associated with a single nucleotide polymorphism mutation in the genetic sequence. Traditionally, these mutations are detected through sequencing, hybridization assays or mini-sequencing. However, these techniques can be expensive and tedious. Previously, CE-SSCP using the F-108 polymer was able to distinguish SNPs for the melanocortin-1 receptor (mc1r) coat color gene in horses (Equus caballus) that differed by one nucleotide substitution. The objective of t...
Monty Roberts’ Public Demonstrations: Preliminary Report on the Heart Rate and Heart Rate Variability of Horses Undergoing Training during Live Audience Events.
Animals : an open access journal from MDPI    September 9, 2016   Volume 6, Issue 9 55 doi: 10.3390/ani6090055
Loftus L, Marks K, Jones-McVey R, Gonzales JL, Fowler VL.Effective training of horses relies on the trainer's awareness of learning theory and equine ethology, and should be undertaken with skill and time. Some trainers, such as Monty Roberts, share their methods through the medium of public demonstrations. This paper describes the opportunistic analysis of beat-to-beat (RR) intervals and heart rate variability (HRV) of ten horses being used in Monty Roberts' public demonstrations within the United Kingdom. RR and HRV was measured in the stable before training and during training. The HRV variables standard deviation of the RR interval (SDRR), root ...
Secretory immunoglobulin A and immunoglobulin G in horse saliva.
Veterinary immunology and immunopathology    September 9, 2016   Volume 180 59-65 doi: 10.1016/j.vetimm.2016.09.001
Palm AE, Wattle O, Lundström T, Wattrang E.This study aimed to increase the knowledge on salivary antibodies in the horse since these constitute an important part of the immune defence of the oral cavity. For that purpose assays to detect horse immunoglobulin A (IgA) including secretory IgA (SIgA) were set up and the molecular weights of different components of the horse IgA system were estimated. Moreover, samples from 51 clinically healthy horses were tested for total SIgA and IgG amounts in saliva and relative IgG3/5 (IgG(T)) and IgG4/7 (IgGb) content were tested in serum and saliva. Results showed a mean concentration of 74μg SIgA...
Factors affecting the efficiency of aerosolized salbutamol delivery via a metered dose inhaler and equine spacer device.
Journal of veterinary pharmacology and therapeutics    September 4, 2016   Volume 40, Issue 3 231-238 doi: 10.1111/jvp.12354
Pirie RS, McGorum BC, Owen C, Carr O, Oakley H, McLachlan G.Despite frequent use of metered dose inhalers (MDIs) and spacers in equine practice, limited information exists on the efficiency of aerosol delivery using such devices. We determined the particle size distribution within an MDI-generated salbutamol aerosol delivered via an equine spacer using 'best practice' delivery technique and assessed the effect of variations in MDI use technique (shaking prior to each actuation, rapid repetitive actuations, and MDI angulation) on aerosol delivery efficiency. Under optimal conditions, only 53(±18) μg salbutamol per 100 μg actuation was delivered bey...
A Survey on Transport Management Practices Associated with Injuries and Health Problems in Horses.
PloS one    September 2, 2016   Volume 11, Issue 9 e0162371 doi: 10.1371/journal.pone.0162371
Padalino B, Raidal SL, Hall E, Knight P, Celi P, Jeffcott L, Muscatello G.An online survey was conducted to determine associations between transport management and transport-related injuries and diseases in horses in Australia. The survey was composed of three sections: respondents' demographic information, transport management strategies or procedures (before, during and after transportation) and transport diseases experienced in the previous two year period. Univariate and multivariate modelling was performed exploring associations between variables (respondents' details and transport management strategies) and the following transport-related diseases as outcomes:...
Women experience needless breast pain when horse-riding.
Nursing standard (Royal College of Nursing (Great Britain) : 1987)    September 1, 2016   Volume 31, Issue 1 17 doi: 10.7748/ns.31.1.17.s21
While 40% of women feel breast pain while riding, fewer than 20% wear a sports bra.
Effects of racetrack surface and nail placement on movement between heels of the hoof and horseshoes of racehorses.
American journal of veterinary research    September 1, 2016   Volume 77, Issue 9 983-990 doi: 10.2460/ajvr.77.9.983
Dahl VE, Hitchens PL, Stover SM.OBJECTIVE To determine the effects of racetrack surface and shoe characteristics on formation of wear grooves in the horseshoes of racehorses. SAMPLES 1,121 horseshoes from 242 Thoroughbred racehorses collected during routine horseshoeing procedures at 4 racetracks with dirt or synthetic surfaces. PROCEDURES Data for 1,014 horseshoes from 233 racehorses were analyzed. Horseshoes were photographed, and length and width of grooves formed at the heels of the solar surface of horseshoes were measured on the photographs. Effects of racetrack, racetrack surface, and shoe characteristics (eg, shoe si...
Identification, characterization and bioactivity of tumor necrosis factor (TNF)-related apoptosis-inducing ligand from Equus caballus.
Developmental and comparative immunology    August 31, 2016   Volume 67 340-349 doi: 10.1016/j.dci.2016.08.018
Ma L, Sang M, Zhang J, Zhang S.Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily and plays multifunctional roles in the immune system. In the present study, a homolog of TRAIL from the Mongolian horse (named ecTRAIL) was identified and characterized. The 870-bp open reading frame encodes a polypeptide of 289 amino acid residues with a predicted molecular weight of 33.47 kDa and pI of 8.47. The genomic structure of ecTRAIL shares a five-exon/six-intron arrangement similar to its orthologs. Multiple alignments show that ecTRAIL is a type II transmembrane protein with a t...
The Influenza NS1 Protein: What Do We Know in Equine Influenza Virus Pathogenesis?
Pathogens (Basel, Switzerland)    August 31, 2016   Volume 5, Issue 3 57 doi: 10.3390/pathogens5030057
Barba M, Daly JM.Equine influenza virus remains a serious health and potential economic problem throughout most parts of the world, despite intensive vaccination programs in some horse populations. The influenza non-structural protein 1 (NS1) has multiple functions involved in the regulation of several cellular and viral processes during influenza infection. We review the strategies that NS1 uses to facilitate virus replication and inhibit antiviral responses in the host, including sequestering of double-stranded RNA, direct modulation of protein kinase R activity and inhibition of transcription and translatio...
Progestin withdrawal at parturition in the mare.
Reproduction (Cambridge, England)    August 29, 2016   Volume 152, Issue 4 323-331 doi: 10.1530/REP-16-0227
Legacki EL, Corbin CJ, Ball BA, Wynn M, Loux S, Stanley SD, Conley AJ.Mammalian pregnancies need progestogenic support and birth requires progestin withdrawal. The absence of progesterone in pregnant mares, and the progestogenic bioactivity of 5α-dihydroprogesterone (DHP), led us to reexamine progestin withdrawal at foaling. Systemic pregnane concentrations (DHP, allopregnanolone, pregnenolone, 5α-pregnane-3β, 20α-diol (3β,20αDHP), 20α-hydroxy-5α-dihydroprogesterone (20αDHP)) and progesterone) were monitored in mares for 10days before foaling (n=7) by liquid chromatography-mass spectrometry. The biopotency of dominant metabolites was assessed using luci...
Molecular Characterization of Equine APRIL and its Expression Analysis During the Adipogenic Differentiation of Equine Adipose-Derived Stem Cell In Vitro.
Animal biotechnology    August 28, 2016   Volume 27, Issue 4 262-268 doi: 10.1080/10495398.2016.1182540
Wu H, Bi X, Cao F, Zhu C, Liu H, Song J, Ma L, Ma L, Zhang Y, Zhao D, Liu H, Xu X, Zhang S.A proliferation inducing ligand (APRIL) is a member of the TNF superfamily. It shares two receptors with B-cell activating factor (BAFF), B-cell maturation antigen (BCMA), and transmembrane activator and CAML interactor (TACI). Herein, the equine APRIL was identified from equine adipose-derived stem cell (ASC), and the protein expression of APRIL and its related molecules were detected during the adipogenic differentiation of equine ASC in vitro. The equine APRIL gene was located on chromosome 11, spans 1852 base pairs (bp). Its open reading frame covers 753 bp, encoding a 250-amino acid prot...
The kinematics and kinetics of riding a racehorse: A quantitative comparison of a training simulator and real horses.
Journal of biomechanics    August 26, 2016   Volume 49, Issue 14 3368-3374 doi: 10.1016/j.jbiomech.2016.08.031
Walker AM, Applegate C, Pfau T, Sparkes EL, Wilson AM, Witte TH.Movement of a racehorse simulator differs to that of a real horse, but the effects of these differences on jockey technique have not been evaluated. We quantified and compared the kinematics and kinetics of jockeys during gallop riding on a simulator and real horses. Inertial measurement units were attached mid-shaft to the long bones of six jockeys and the sacrum of the horse or simulator. Instrumented stirrups were used to measure force. Data were collected during galloping on a synthetic gallop or while riding a racehorse simulator. Jockey kinematics varied more on a real horse compared to ...
How realistic is a racehorse simulator?
Journal of biomechanics    August 25, 2016   Volume 49, Issue 14 3570-3575 doi: 10.1016/j.jbiomech.2016.08.026
Walker AM, Martin A, Pfau T, Sparkes EL, Wilson AM, Witte TH.Race jockey training is demanding and technical. Increased horse care costs and demands on time have led to greater availability and use of racehorse simulators during training. Little is known about the accuracy of the simulated movement and therefore how effective they are for developing the desired technique. We quantified and compared sacral rotation and displacement vectors for a racehorse simulator and a real galloping horse. A single inertial measurement unit was placed on the sacrum of six horses (horse) during a training gallop along an all-weather seven furlong gallop and on the high...
Making the Diagnosis.
Veterinary pathology    August 20, 2016   Volume 54, Issue 1 9-10 doi: 10.1177/0300985816664793
Wobeser BK.No abstract available
Description of two equine nematodes, Parascaris equorum Goeze 1782 and Habronema microstoma Schneider 1866 from the domestic horse Equus ferus caballus (Famisly: Equidae) in Egypt.
Parasitology research    August 19, 2016   Volume 115, Issue 11 4299-4306 doi: 10.1007/s00436-016-5212-1
Morsy K, Bashtar AR, Al Quraishy S, Adel S.Parasitic gastroenteritis (PGE) caused by infection of the gut with parasitic nematodes is one of the most important diseases of livestock animals from both financial and welfare perspectives. Parascaris equorum and Habronema microstoma are of the most endemic nematodes of the world which are currently the major cause of PGE of the domestic horses in Egypt. The present investigation introduced the first morphological description of these nematodes recovered from the domestic horse, Equus ferus caballus (Equidae), in Egypt by light and scanning electron microscopy. Seven P. equorum (fifth stage...
The mane effect in the horse (Equus ferus caballus): Right mane dominance enhanced in mares but not associated with left and right manoeuvres in a reining competition.
Laterality    August 18, 2016   Volume 22, Issue 4 495-513 doi: 10.1080/1357650X.2016.1219740
Whishaw IQ, Kolb B.A human physical asymmetry is the near 90% clockwise occipitoparietal scalp hair-whorl direction in Europeans, an incidence that approximates the left lateralization of speech and right-handedness. Hair-whorl direction is also asymmetric in horses, Equus ferus caballus and placement is proposed to be related to temperament and lateralized skill in equitation manoeuvres. We describe a hair-whorl asymmetry in the horse, mane direction. Of 526, 3-year-old American Quarter horses, 69% of horses had mane directed to the right and 31% had mane directed to the left. The bias was larger in females, wi...
Induction of Tenogenic Differentiation Mediated by Extracellular Tendon Matrix and Short-Term Cyclic Stretching.
Stem cells international    August 18, 2016   Volume 2016 7342379 doi: 10.1155/2016/7342379
Burk J, Plenge A, Brehm W, Heller S, Pfeiffer B, Kasper C.Tendon and ligament pathologies are still a therapeutic challenge, due to the difficulty in restoring the complex extracellular matrix architecture and biomechanical strength. While progress is being made in cell-based therapies and tissue engineering approaches, comprehensive understanding of the fate of progenitor cells in tendon healing is still lacking. The aim of this study was to investigate the effect of decellularized tendon matrix and moderate cyclic stretching as natural stimuli which could potentially direct tenogenic fate. Equine adipose-derived mesenchymal stromal cells (MSC) were...
Accessing the equine elbow joint: new insights on an old approach.
The Veterinary record    August 16, 2016   Volume 179, Issue 7 170-172 doi: 10.1136/vr.i4427
Baccarin RY.No abstract available
Freedoms and frameworks: How we think about the welfare of competition horses.
Equine veterinary journal    August 16, 2016   Volume 48, Issue 5 540-542 doi: 10.1111/evj.12598
Campbell ML.No abstract available
Occupational allergy to horse allergens: More than exposure to horses!
International journal of occupational medicine and environmental health    August 16, 2016   Volume 29, Issue 5 721-723 doi: 10.13075/ijomeh.1896.00770
No abstract available
Science in brief: Keeping up progress with equine dental research.
Equine veterinary journal    August 16, 2016   Volume 48, Issue 5 537-539 doi: 10.1111/evj.12588
Dixon PM, Nicholls V.No abstract available
[Riding therapy in the rehabilitation of mobility-impaired children].
Duodecim; laaketieteellinen aikakauskirja    August 16, 2016   Volume 132, Issue 13-14 1279-1285 
Mäenpää H, Kela K, Sätilä H.Riding therapy is a comprehensive and functional form of rehabilitation, in which the rehabilitee, the horse and the riding therapist collaborate in order to achieve individually assigned goals that support rehabilitation. In Finland, riding therapy is therapeutic rehabilitation carried out by riding therapists who have undergone approved training. The therapy is mainly implemented in an individual form, but small group working is also applied, e.g. in the form of pair therapy and therapeutic vaulting. In Europe, this form of rehabilitation has been divided into hippotherapy supporting motor f...
Age-Related Changes in Locomotor Performance Reveal a Similar Pattern for Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens.
The journals of gerontology. Series A, Biological sciences and medical sciences    August 16, 2016   Volume 72, Issue 4 455-463 doi: 10.1093/gerona/glw136
Marck A, Berthelot G, Foulonneau V, Marc A, Antero-Jacquemin J, Noirez P, Bronikowski AM, Morgan TJ, Garland T, Carter PA, Hersen P, Di Meglio JM....Locomotion is one of the major physiological functions for most animals. Previous studies have described aging mechanisms linked to locomotor performance among different species. However, the precise dynamics of these age-related changes, and their interactions with development and senescence, are largely unknown. Here, we use the same conceptual framework to describe locomotor performances in Caenorhabditis elegans, Mus domesticus, Canis familiaris, Equus caballus, and Homo sapiens. We show that locomotion is a consistent biomarker of age-related changes, with an asymmetrical pattern througho...
Central Nervous System and Vertebrae Development in Horses: a Chronological Study with Differential Temporal Expression of Nestin and GFAP.
Journal of molecular neuroscience : MN    August 15, 2016   Volume 61, Issue 1 61-78 doi: 10.1007/s12031-016-0805-9
Rigoglio NN, Barreto RS, Favaron PO, Jacob JC, Smith LC, Gastal MO, Gastal EL, Miglino MA.The neural system is one of the earliest systems to develop and the last to be fully developed after birth. This study presents a detailed description of organogenesis of the central nervous system (CNS) at equine embryonic/fetal development between 19 and 115 days of pregnancy. The expression of two important biomarkers in the main structure of the nervous system responsible for neurogenesis in the adult individual, and in the choroid plexus, was demonstrated by Nestin and glial fibrillary acid protein (GFAP) co-labeling. In the 29th day of pregnancy in the undifferentiated lateral ventricle...
Alkaline phosphatase added to capacitating medium enhances horse sperm-zona pellucida binding.
Theriogenology    August 13, 2016   Volume 87 72-78 doi: 10.1016/j.theriogenology.2016.08.003
Bucci D, Giaretta E, Merlo B, Iacono E, Spinaci M, Gadani B, Mari G, Tamanini C, Galeati G.Alkaline phosphatase (AP) is present in equine seminal plasma and spermatozoa, but its functional role is not fully understood yet. Being that, sperm-oocyte interaction in equine species has been reported to be enhanced at a slightly basic pH, this work aimed at verifying whether exogenous alkaline phosphatase exerts any role on stallion spermatozoa and sperm-oocyte interaction at different pHs (7.4; 8.0; 9.0). Stallion spermatozoa were capacitated in Tyrode's medium at pH 7.4, 8.0, and 9.0 for 4 hours at 38 °C, 5% CO with 2.5-IU AP (AP group) or without AP (capacitated spermatozoa group); ...
Reproductive stage-dependent effects of additional cryoprotectant agents for the cryopreservation of stallion germ cells.
Animal reproduction science    August 12, 2016   Volume 173 24-28 doi: 10.1016/j.anireprosci.2016.08.005
Jung H, Kim N, Yoon M.The main objective of this study was to evaluate the efficacy of an additional cryoprotectant in 10% dimethyl sulfoxide (DMSO) on cryopreserving germ cells from stallions at different reproductive stages. Testicular samples were obtained from pre-pubertal (1-1.5 yr, n=6) and post-pubertal (3-7 yr, n=5) stallions. Germ cells were isolated using a two-enzyme digestion procedure and cryopreserved in minimal essential medium alpha containing 10% fetal bovine serum and 10% DMSO with or without addition of trehalose (50, 100, or 200mM) or polyethylene glycol (PEG, 2.5, 5, or 10%). Viability, cell po...
Identification and characterization of equine blood plasmacytoid dendritic cells.
Developmental and comparative immunology    August 11, 2016   Volume 65 352-357 doi: 10.1016/j.dci.2016.08.005
Ziegler A, Marti E, Summerfield A, Baumann A.Dendritic cells (DC) are antigen-presenting cells that can be classified into three major cell subsets: conventional DC1 (cDC1), cDC2 and plasmacytoid DCs (pDC), none of which have been identified in horses. Therefore, the objective of this study was to identify and characterize DC subsets in equine peripheral blood, emphasizing on pDC. Surface marker analysis allowed distinction of putative DC subsets, according to their differential expression of CADM-1 and MHC class II. Equine pDC were found to be Flt3(+) CD4(low) CD13(-) CD14(-) CD172a(-) CADM-1(-) MHCII(low). The weak expression of CD4 on...
The origin of ambling horses.
Current biology : CB    August 10, 2016   Volume 26, Issue 15 R697-R699 doi: 10.1016/j.cub.2016.07.001
Wutke S, Andersson L, Benecke N, Sandoval-Castellanos E, Gonzalez J, Hallsson JH, Lõugas L, Magnell O, Morales-Muniz A, Orlando L, Pálsdóttir AH....Horseback riding is the most fundamental use of domestic horses and has had a huge influence on the development of human societies for millennia. Over time, riding techniques and the style of riding improved. Therefore, horses with the ability to perform comfortable gaits (e.g. ambling or pacing), so-called 'gaited' horses, have been highly valued by humans, especially for long distance travel. Recently, the causative mutation for gaitedness in horses has been linked to a substitution causing a premature stop codon in the DMRT3 gene (DMRT3_Ser301STOP) [1]. In mice, Dmrt3 is expressed in spinal...