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Topic:Exercise Physiology

Exercise physiology in horses involves the study of the physiological responses and adaptations of horses to physical activity. This field examines how exercise impacts various systems in the equine body, including the cardiovascular, respiratory, muscular, and metabolic systems. Researchers focus on understanding how these systems interact during different types and intensities of exercise, and how they contribute to performance and recovery. Key areas of interest include the assessment of aerobic and anaerobic capacity, muscle fiber composition, energy metabolism, and thermoregulation. This page compiles peer-reviewed research studies and scholarly articles that explore the mechanisms of exercise physiology in horses, with an emphasis on performance optimization, training regimens, and the prevention of exercise-related disorders.
Response of biochemical markers of bone metabolism to exercise intensity in thoroughbred horses.
Journal of equine science    January 9, 2009   Volume 19, Issue 4 83-89 doi: 10.1294/jes.19.83
Inoue Y, Matsui A, Asai Y, Aoki F, Yoshimoto K, Matsui T, Yano H.We studied the response of biochemical markers of bone metabolism to exercise intensity in horses. Four horses were walked on a mechanical walker for one week (pre-exercise). Then they performed low-speed exercise on a high-speed treadmill in the first week and medium-speed exercise in the second week and high-speed exercise in the third week of training. We measured two indices of bone resorption, serum hydroxyproline concentration and the urinary deoxypyridinoline/creatinine ratio, and serum osteocalcin (OC) concentration as an index of bone formation. Both indices of bone resorption gradual...
Effects of competition experience and transportation on the adrenocortical and thyroid responses of horses.
The Veterinary record    December 17, 2008   Volume 163, Issue 24 713-716 doi: 10.1136/vr.163.24.713
Fazio E, Medica P, Cravana C, Ferlazzo A.To evaluate whether the amount of experience of sport horses and the stress of transport affected their adrenocortical and thyroid responses, the plasma concentrations of total cortisol and total and free iodothyronine of 63 horses were studied before and after show jumping competitions. There were 14 trained inexperienced jumpers (group 1), 20 trained experienced jumpers (group 2), 10 trained inexperienced jumpers that had been transported just before the competition (group 3) and 19 trained experienced jumpers that had been transported just before the competition (group 4). The concentration...
Transient increase with strenuous exercise of plasma levels of glycosaminoglycans in humans and horses.
Connective tissue research    December 17, 2008   Volume 49, Issue 6 416-425 doi: 10.1080/03008200802324949
Calatroni A, Avenoso A, Ferlazzo AM, Lindner A, Campo GM.Plasma glycosaminoglycans (GAGs) were isolated and purified by chromatographic procedures in healthy humans and horses before and after physical exercise. A weak anion exchange resin was used to separate polyanions. Humans exercised on a cycloergometer, while horses were exercised on a treadmill and in show jumping competition. Some GAGs were isolated from untreated plasma and operationally defined as native proteoglycans (PGs), while the total GAG amount was isolated from mild alkali treated plasma. Plasma GAG concentrations in terms of galactosamine and galactose, the respective components o...
Ultrasonographic and Doppler findings of subclinical clitoral microtraumatisms in mountain bikers and horseback riders.
The journal of sexual medicine    December 9, 2008   Volume 6, Issue 2 464-468 doi: 10.1111/j.1743-6109.2008.01124.x
Battaglia C, Nappi RE, Mancini F, Cianciosi A, Persico N, Busacchi P.Repeated microtraumas in horseback riders and mountain bikers are, in males, associated with perineal and scrotal lesions. No data are reported in the females. Objective: To report five cases of clitoral microcalcifications, diagnosed by ultrasonography, in six healthy, eumenorrheic athletes, and to verify the clinical and sexual impact of the ultrasonographic findings. Methods: Translabial ultrasonographic evaluation of the clitoris, Doppler analysis of dorsal clitoral arteries, and the two-factor Italian McCoy Female Sexuality Questionnaire (MFSQ) METHODS: The patients were assessed with a d...
Effects of intravenous administration of caffeine on physiologic variables in exercising horses.
American journal of veterinary research    December 3, 2008   Volume 69, Issue 12 1670-1675 doi: 10.2460/ajvr.69.12.1670
Ferraz GC, Teixeira-Neto AR, Mataqueiro MI, Lacerda-Neto JC, Queiroz-Neto A.To investigate the effect of acute administration of caffeine on the athletic performance of Arabian horses. Methods: 12 healthy adult Arabian horses that were trained for exercise on a treadmill. Methods: By use of a crossover study design, horses received each of the following treatments: IV administration of caffeine (5 mg/kg) and IV administration of approximately the same volume of saline (0.9% NaCl) solution. Order of treatment was randomized, and there was a 10-day interval between treatments. Thirty minutes after treatments, horses underwent an incremental exercise test (IET) on a trea...
Limits to running speed in dogs, horses and humans.
The Journal of experimental biology    December 2, 2008   Volume 211, Issue Pt 24 3836-3849 doi: 10.1242/jeb.024968
Denny MW.Are there absolute limits to the speed at which animals can run? If so, how close are present-day individuals to these limits? I approach these questions by using three statistical models and data from competitive races to estimate maximum running speeds for greyhounds, thoroughbred horses and elite human athletes. In each case, an absolute speed limit is definable, and the current record approaches that predicted maximum. While all such extrapolations must be used cautiously, these data suggest that there are limits to the ability of either natural or artificial selection to produce ever fast...
Resting concentrations of cardiac troponin I in fit horses and effect of racing.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    November 18, 2008   Volume 10, Issue 2 105-109 doi: 10.1016/j.jvc.2008.10.001
Nostell K, Häggström J.To determine normal resting values for cardiac troponin I (cTnI) in healthy Standardbred, Thoroughbred and Warmblood horses and investigate if racing has an influence on cTnI concentrations. Background: Measuring cTnI concentrations in plasma is the gold standard for detecting myocardial injury in humans. Cardiac troponin I is highly conserved between species and has gained interest as a marker for cardiac injury in horses. Increased levels of cTnI have been reported in association with endurance and short-term strenuous exercise on a treadmill in horses. However, the effect of true racing con...
Atrial and ventricular electrical and contractile remodeling and reverse remodeling owing to short-term pacing-induced atrial fibrillation in horses.
Journal of veterinary internal medicine    November 13, 2008   Volume 22, Issue 6 1353-1359 doi: 10.1111/j.1939-1676.2008.0202.x
De Clercq D, van Loon G, Tavernier R, Duchateau L, Deprez P.In humans, atrial fibrillation (AF) induces electrical, contractile, and structural remodeling leading to AF stabilization. Little is known about AF-induced atrial remodeling in horses. Objective: Induced AF produces rapid atrial electrical and contractile remodeling in horses. Methods: Six horses, 5 animals completed the study. Methods: Each horse was instrumented with a pulse generator and pacemaker to maintain AF by burst pacing and to study atrial and ventricular electrophysiology (AF cycle length [AFCL], AF duration, and atrial/ventricular effective refractory period [AERP/VERP] at differ...
The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise.
Acta veterinaria Scandinavica    November 7, 2008   Volume 50, Issue 1 45 doi: 10.1186/1751-0147-50-45
Marañón G, Muñoz-Escassi B, Manley W, García C, Cayado P, de la Muela MS, Olábarri B, León R, Vara E.Exercise induces changes in several organs and tissues, and this process might be due to oxidative damage caused by free radicals and inflammatory mediators. Methyl Sulphonyl Methane, better known as MSM, is a naturally occurring sulphur compound with well-known antioxidant properties. On the other hand, Vitamin C is important in limiting free radical damage in the aqueous phase of the cell, and cellular vitamin C status may be linked to the mechanisms involved in quenching cellular reactive oxygen species. The aim of this study was to determine if supplementation with MSM and vitamin C could ...
Plasma acylcarnitine and fatty acid profiles during exercise and training in Standardbreds.
American journal of veterinary research    November 5, 2008   Volume 69, Issue 11 1469-1475 doi: 10.2460/ajvr.69.11.1469
Westermann CM, Dorland B, de Sain-van der Velden MG, Wijnberg ID, Van Breda E, De Graaf-Roelfsema E, Keizer HA, Van der Kolk JH.To evaluate alterations in skeletal muscle carnitine metabolism during exercise and training by measuring changes in plasma acylcarnitine concentrations in Standardbreds. Methods: 10 Standardbred geldings with a mean +/- SD age of 20 +/- 2 months and weight of 384 +/- 42 kg. Methods: In a 32-week longitudinal study, training on a treadmill was divided into 4 phases as follows: phase 1, acclimatization for 4 weeks; phase 2, 18 weeks with alternating endurance and high-intensity exercise training; phase 3, increased training volume and intensity for another 6 weeks; and phase 4, deconditioning f...
Young horse response on changing distance in free jumping combination.
Animal : an international journal of animal bioscience    November 1, 2008   Volume 2, Issue 11 1651-1657 doi: 10.1017/S1751731108002863
Lewczuk D.The aim of the present study was to verify the influence of distance between obstacles in combination for free jumping test on linear and temporal kinematic parameters of the jump. Investigated groups of halfbred stallions being prepared for 100 days performance test (two groups, 36 horses in total) were filmed on different distances between main doublebarre obstacle and last cross-pole in the jumping lane. Both groups of horses were filmed during their regular work in the same training centre 1 week before performance test. Jumping parameters were obtained on the same size of the obstacle. Da...
Profiling training preparation in young Australian Thoroughbred racehorses.
Australian veterinary journal    October 31, 2008   Volume 86, Issue 11 419-424 doi: 10.1111/j.1751-0813.2008.00358.x
Cogger N, Perkins N, Hodgson DR, Reid SW, Evans DL.To describe the impact of age, sex, and musculoskeletal (MS) injury on three preparation-level measures of performance: (i) the duration of preparation, (ii) time from the beginning of the preparation until the first start in a race or barrier trial, and (iii) time from the first start until the end of the preparation. Methods: Daily training and injury data for 2- and 3-year old Thoroughbred racehorses were collected fortnightly from 14 trainers in NSW, Australia. Training data were aggregated into units referred to as 'preparations'. Univariate and multivariate analytical methods were used t...
Fluid and electrolyte supplementation after prolonged moderate-intensity exercise enhances muscle glycogen resynthesis in Standardbred horses.
Journal of applied physiology (Bethesda, Md. : 1985)    October 23, 2008   Volume 106, Issue 1 91-100 doi: 10.1152/japplphysiol.90783.2008
Waller AP, Heigenhauser GJ, Geor RJ, Spriet LL, Lindinger MI.We hypothesized that postexercise rehydration using a hypotonic electrolyte solution will increase the rate of recovery of whole body hydration, and that this is associated with increased muscle glycogen and electrolyte recovery in horses. Gluteus medius biopsies and jugular venous blood were sampled from six exercise-conditioned Standardbreds on two separate occasions, at rest and for 24 h following a competitive exercise test (CET) designed to simulate the speed and endurance test of a 3-day event. After the CETs, horses were given water ad libitum, and either a hypotonic commercial electrol...
Motions of the running horse and cheetah revisited: fundamental mechanics of the transverse and rotary gallop.
Journal of the Royal Society, Interface    October 14, 2008   Volume 6, Issue 35 549-559 doi: 10.1098/rsif.2008.0328
Bertram JE, Gutmann A.Mammals use two distinct gallops referred to as the transverse (where landing and take-off are contralateral) and rotary (where landing and take-off are ipsilateral). These two gallops are used by a variety of mammals, but the transverse gallop is epitomized by the horse and the rotary gallop by the cheetah. In this paper, we argue that the fundamental difference between these gaits is determined by which set of limbs, fore or hind, initiates the transition of the centre of mass from a downward-forward to upward-forward trajectory that occurs between the main ballistic (non-contact) portions o...
Physical activity: does long-term, high-intensity exercise in horses result in tendon degeneration?
Journal of applied physiology (Bethesda, Md. : 1985)    October 2, 2008   Volume 105, Issue 6 1927-1933 doi: 10.1152/japplphysiol.00717.2007
Birch HL, Wilson AM, Goodship AE.This study explores the hypothesis that high-intensity exercise induces degenerative changes in the injury-prone equine superficial digital flexor tendon (SDFT), but not in the rarely injured common digital extensor tendon (CDET). The horse represents a large-animal model that is applicable to human tendon and ligament physiology and pathology. Twelve age-matched female horses undertook galloping exercise three times a week with trotting exercise on alternative days (high-intensity group, n = 6) or only walking exercise (low-intensity group, n = 6) for 18 mo. The SDFT, suspensory ligament, dee...
(Over)training effects on quantitative electromyography and muscle enzyme activities in standardbred horses.
Journal of applied physiology (Bethesda, Md. : 1985)    October 2, 2008   Volume 105, Issue 6 1746-1753 doi: 10.1152/japplphysiol.01272.2007
Wijnberg ID, van Dam KG, Graaf-Roelfsema Ed, Keizer HA, van Ginneken MM, Barneveld A, Breda Ev, van der Kolk JH.Too intensive training may lead to overreaching or overtraining. To study whether quantitative needle electromyography (QEMG) is more sensitive to detect training (mal)adaptation than muscle enzyme activities, 12 standardbred geldings trained for 32 wk in age-, breed-, and sex-matched fixed pairs. After a habituation and normal training (NT) phase (phases 1 and 2, 4 and 18 wk, respectively), with increasing intensity and duration and frequency of training sessions, an intensified training (IT) group (phase 3, 6 wk) and a control group (which continued training as in the last week of phase 2) w...
Contractile behavior of the forelimb digital flexors during steady-state locomotion in horses (Equus caballus): an initial test of muscle architectural hypotheses about in vivo function.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology    September 20, 2008   Volume 152, Issue 1 100-114 doi: 10.1016/j.cbpa.2008.09.007
Butcher MT, Hermanson JW, Ducharme NG, Mitchell LM, Soderholm LV, Bertram JE.The forelimb digital flexors of the horse display remarkable diversity in muscle architecture despite each muscle-tendon unit having a similar mechanical advantage across the fetlock joint. We focus on two distinct muscles of the digital flexor system: short compartment deep digital flexor (DDF(sc)) and the superficial digital flexor (SDF). The objectives were to investigate force-length behavior and work performance of these two muscles in vivo during locomotion, and to determine how muscle architecture contributes to in vivo function in this system. We directly recorded muscle force (via ten...
Effects of vitamin E and selenium on serum trace and major elements in horses.
Biological trace element research    September 17, 2008   Volume 125, Issue 3 223-228 doi: 10.1007/s12011-008-8109-8
Yur F, Dede S, Deger Y, Kilicalp D.The combined effects of vitamin E and selenium were studied in native Anatolian horses subject to strenuous exercise. The concentrations of copper, zinc, iron, calcium, potassium, and magnesium were determined in serum by atomic absorption spectrometry in two study groups (n = 25 each), one of which served as untreated controls. After exercising the horses by running 1,500 m in about 7 min, only the copper level and the copper/zinc ratio significantly increased (p < 0.05), but the concentrations of calcium, potassium, iron, and magnesium remained unchanged. In horses treated with vitamin E ...
Hemorheopathy in exercising horses.
Clinical hemorheology and microcirculation    September 16, 2008   Volume 40, Issue 1 73-75 
Boucher JH, Connes P.No abstract available
Growth hormone secretion in relation to plasma lactate and glucose concentrations during a maximal treadmill exercise test in horses.
Veterinary research communications    August 9, 2008   Volume 32 Suppl 1 S111-S113 doi: 10.1007/s11259-008-9104-4
Borromeo V, Ferrucci F, Zucca E, Berrini A, Secchi C.No abstract available
Cardiac output determination by use of lithium dilution during exercise in horses.
American journal of veterinary research    August 5, 2008   Volume 69, Issue 8 1054-1060 doi: 10.2460/ajvr.69.8.1054
Durando MM, Corley KT, Boston RC, Birks EK.To compare cardiac output (CO) obtained by the lithium dilution method (LiDCO) with CO calculated from the Fick principle (FickCO), in horses maximally exercising on a high-speed treadmill. Methods: 13 Thoroughbreds. Methods: In part 1 of the study, 5 horses performed a warm-up (walk, trot, and canter) and exercise test (walk, trot, canter, and gallop [90% to 100% maximum oxygen consumption [{VO(2)max}]) with measurements of LiDCO and FickCO obtained simultaneously after 60 seconds at each exercise level, for a total of 7 measurements. In part 2 of the study, 8 horses performed a warm-up (walk...
Walk-run classification of symmetrical gaits in the horse: a multidimensional approach.
Journal of the Royal Society, Interface    July 29, 2008   Volume 6, Issue 33 335-342 doi: 10.1098/rsif.2008.0238
Starke SD, Robilliard JJ, Weller R, Wilson AM, Pfau T.Walking and running are two mechanisms for minimizing energy expenditure during terrestrial locomotion. Duty factor, dimensionless speed, existence of an aerial phase, percentage recovery (PR) or phase shift of mechanical energy and shape of the vertical ground reaction force profile have been used to discriminate between walking and running. Although these criteria work well for the classification of most quadrupedal gaits, they result in conflicting evidence for some gaits, such as the tölt (a symmetrical, four-beat gait used by Icelandic horses). We use established pattern recognition meth...
Clinical pathology in the racing horse: the role of clinical pathology in assessing fitness and performance in the racehorse.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 405-vii doi: 10.1016/j.cveq.2008.03.001
McGowan C.Clinical pathology is frequently used in racehorses to screen for "fitness" to race and to screen for disease that may affect performance. The role of clinical pathology in exercise testing of racehorses is important, especially in the area of blood lactate responses to exercise. This article discusses the use of resting and dynamic clinical pathology in the racehorse, especially in respect to investigation of the state of training (or fitness) and detection of subclinical performance-limiting disease.
Assessing the rider’s seat and horse’s behavior: difficulties and perspectives.
Journal of applied animal welfare science : JAAWS    June 24, 2008   Volume 11, Issue 3 191-203 doi: 10.1080/10888700802100876
Blokhuis MZ, Aronsson A, Hartmann E, Van Reenen CG, Keeling L.A correct seat and position are the basis for a good performance in horseback riding. This study aimed to measure deviations from the correct seat, test a seat improvement program (dismounted exercises), and investigate whether horse behavior was affected by the rider's seat. Five experienced trainers defined 16 seat deviations and scored the occurrence in 20 riders in a dressage test. Half the riders then carried out an individual training program; after 9 weeks, riders were again scored. The study took no video or heart-rate recordings of horses and riders. Panel members did not agree on the...
[Specific riding styles are associated with specific effects on bodily posture control].
Sportverletzung Sportschaden : Organ der Gesellschaft fur Orthopadisch-Traumatologische Sportmedizin    June 11, 2008   Volume 22, Issue 2 93-99 doi: 10.1055/s-2008-1027394
Schwesig R, Sannemüller K, Kolditz R, Hottenrott K, Becker S, Esperer HD.The assessment of body posture control can be time consuming and cumbersome due to the complexity and the multimodal influence of a multiply influenced system. Various types of equine paces, such as stepping, trotting or galloping, result in acceleration and deceleration forces of different magnitude. These forces induce, in the horseman, reflexes that mediate motor activity to sustain posture balance and counterbalance the gravitational pull. However, there is a paucity of real life data regarding the extent of the various postural subsystems that are recruited to control postural balance in ...
Short-term habituation of equine limb kinematics to tactile stimulation of the coronet.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    June 10, 2008   Volume 21, Issue 3 211-214 
Clayton HM, White AD, Kaiser LJ, Nauwelaerts S, Lavagnino M, Stubbs NC.A lightweight bracelet that provides tactile stimulation to the horse's pastern and coronet induces a higher flight arc of the hoof. This study addresses the pattern of habituation to these devices. Objective: To evaluate short-term habituation to tactile stimulation of the pastern and coronet in trotting horses. Methods: Tactile stimulation was provided by a lightweight (55 g) device consisting of a strap with seven chains that was attached loosely around the pastern. Reflective markers were fixed to the dorsal hoof wall, the forehead and over the tenth thoracic vertebra of eight sound horses...
Effects of warm-up intensity on oxygen transport during supramaximal exercise in horses.
American journal of veterinary research    May 2, 2008   Volume 69, Issue 5 690-696 doi: 10.2460/ajvr.69.5.690
Mukai K, Hiraga A, Eto D, Takahashi T, Hada T, Tsubone H, Jones JH.To determine whether warm-up exercise at different intensities alters kinetics and total contribution of aerobic power to total metabolic power in subsequent supramaximal exercise in horses. Methods: 11 horses. Methods: Horses ran at a sprint until fatigued at 115% of maximal oxygen consumption rate (VO(2max)), beginning at 10 minutes following each of 3 warm-up protocols: no warmup (NoWU), 1 minute at 70% VO(2max) (moderate-intensity warm-up [MoWU]), or 1 minute at 115% VO(2max) (high-intensity warm-up [HiWU]). Cardiopulmonary and blood gas variables were measured during exercise. Results: Th...
Activity of selected rostral and caudal hyoid muscles in clinically normal horses during strenuous exercise.
American journal of veterinary research    May 2, 2008   Volume 69, Issue 5 682-689 doi: 10.2460/ajvr.69.5.682
Morello SL, Ducharme NG, Hackett RP, Warnick LD, Mitchell LM, Soderholm LV.To determine the phase and quantitate the electromyographic (EMG) activity of the genioglossus, geniohyoideus, hyoepiglotticus, omohyoideus, sternohyoideus, sternothyroideus, and thyrohyoideus muscles of clinically normal horses during strenuous exercise. Methods: 7 clinically normal adult horses (2 Thoroughbreds and 5 Standardbreds). Methods: Bipolar electrodes were surgically implanted in the aforementioned muscles, and horses were subjected to an incremental exercise test on a high-speed treadmill. The EMG, heart rate, respiratory rate, and static pharyngeal airway pressures were measured d...
Changes in synovial fluid and serum biomarkers with exercise and early osteoarthritis in horses.
Osteoarthritis and cartilage    April 28, 2008   Volume 16, Issue 10 1196-1204 doi: 10.1016/j.joca.2008.03.008
Frisbie DD, Al-Sobayil F, Billinghurst RC, Kawcak CE, McIlwraith CW.To discriminate between changes in biomarkers with exercise compared to changes in biomarkers with osteoarthritis (OA) in exercising horses. Methods: Sixteen, 2-year-old horses were randomly assigned either to an exercise-alone (n=8) or OA-affected (also exercised) (n=8) group. All horses had both mid-carpal joints arthroscoped and OA induced in one mid-carpal joint in the OA-affected joints of OA-affected horses. Two weeks after surgery all horses commenced a strenuous exercise program on a high-speed treadmill. Clinical outcomes and synovial fluid and serum biomarkers, were evaluated weekly....
Dietary energy source affects glucose kinetics in trained Arabian geldings at rest and during endurance exercise.
The Journal of nutrition    April 22, 2008   Volume 138, Issue 5 964-970 doi: 10.1093/jn/138.5.964
Treiber KH, Geor RJ, Boston RC, Hess TM, Harris PA, Kronfeld DS.Advances in modeling and tracer techniques provide new perspective into glucose utilization and potential consequences to health or exercise performance. This study used stable isotope and compartmental modeling to evaluate how adaptation to a feed high in sugar and starch (SS) compared with a feed high in fat and fiber (FF) affects glucose kinetics at rest and during exercise in horses. Six trained Arabians adapted to each feed underwent similar tests at rest and while running approximately 4 m/s on a treadmill. For both tests, horses received 100 micromol/kg body weight [6,6-(2)H]glucose thr...
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