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Topic:Exercise

Exercise in horses encompasses the physical activities that horses engage in, either through natural behaviors or structured training programs. These activities impact a horse's musculoskeletal, cardiovascular, and respiratory systems, influencing overall health and performance. Exercise can vary in intensity, duration, and frequency, and its effects are studied to understand conditioning, endurance, and recovery processes in equines. Research in this field often focuses on the physiological adaptations to different types of exercise, the prevention of exercise-related injuries, and the optimization of training regimens for various equestrian disciplines. This page compiles peer-reviewed research studies and scholarly articles that explore the physiological, biomechanical, and health-related aspects of exercise in horses.
Effects of vitamin E and selenium on serum trace and major elements in horses.
Biological trace element research    September 17, 2008   Volume 125, Issue 3 223-228 doi: 10.1007/s12011-008-8109-8
Yur F, Dede S, Deger Y, Kilicalp D.The combined effects of vitamin E and selenium were studied in native Anatolian horses subject to strenuous exercise. The concentrations of copper, zinc, iron, calcium, potassium, and magnesium were determined in serum by atomic absorption spectrometry in two study groups (n = 25 each), one of which served as untreated controls. After exercising the horses by running 1,500 m in about 7 min, only the copper level and the copper/zinc ratio significantly increased (p < 0.05), but the concentrations of calcium, potassium, iron, and magnesium remained unchanged. In horses treated with vitamin E ...
Exercise does not affect stiffness and mineralisation of third metacarpal condylar subarticular calcified tissues in 2 year old thoroughbred racehorses.
European cells & materials    September 17, 2008   Volume 16 40-46 doi: 10.22203/ecm.v016a05
Ferguson VL, Bushby AJ, Firth EC, Howell PG, Boyde A.Impact exercise has a profound effect in increasing volumetric density of epiphyseal bone, as clearly shown in 2 year old thoroughbred racehorses from which we derived the tissue studied in the present investigation. Here, we asked the question whether the fabric-level properties of the mineralised tissues immediately below hyaline articular cartilage which transmit the extra loads are themselves altered in consequence. We therefore studied the nanoindentation elastic modulus and its relationship to the concentration of mineral determined by quantitative backscattered electron imaging in the h...
Hemorheopathy in exercising horses.
Clinical hemorheology and microcirculation    September 16, 2008   Volume 40, Issue 1 73-75 
Boucher JH, Connes P.No abstract available
Osteochondral injury increases type II collagen degradation products (C2C) in synovial fluid of Thoroughbred racehorses.
Osteoarthritis and cartilage    September 16, 2008   Volume 17, Issue 3 371-374 doi: 10.1016/j.joca.2008.07.014
Trumble TN, Scarbrough AB, Brown MP.To investigate the effects of exercise and osteochondral (OC) injury on type II collagen degradation products (collagenase cleavage neoepitope commercially known as C2C) in synovial fluid (SF) from Thoroughbred (TB) racehorses and to compare these results with radiographic and arthroscopic scores of severity of joint injury. Methods: Metacarpophalangeal/metatarsophalangeal (MCP/MTP) and carpal SF was obtained from (1) 20 normal rested horses, (2) the same horses after 5 to 6 months of race training, and (3) 27 horses with OC injury from racing. For group 3, radiographic and arthroscopic scores...
Validation of thromboelastometry in horses.
Veterinary clinical pathology    September 3, 2008   Volume 37, Issue 3 277-285 doi: 10.1111/j.1939-165X.2008.00052.x
Paltrinieri S, Meazza C, Giordano A, Tunesi C.Thromboelastometry is used for identifying or monitoring coagulation abnormalities. It has been validated in several species but not in horses and the characteristics of the equine thromboelastogram have not yet been detailed. Objective: The purpose of this study was to validate a thromboelastometer to be used with equine blood and to define the normal equine thromboelastogram. Methods: A Rotem-gamma thromboelastometer (Pentapharm GmbH, Munich, Germany) was used on 38 citrated blood samples to investigate native coagulation, the intrinsic and extrinsic pathways, the function of fibrinogen (lar...
Cardiac output determination by use of lithium dilution during exercise in horses.
American journal of veterinary research    August 5, 2008   Volume 69, Issue 8 1054-1060 doi: 10.2460/ajvr.69.8.1054
Durando MM, Corley KT, Boston RC, Birks EK.To compare cardiac output (CO) obtained by the lithium dilution method (LiDCO) with CO calculated from the Fick principle (FickCO), in horses maximally exercising on a high-speed treadmill. Methods: 13 Thoroughbreds. Methods: In part 1 of the study, 5 horses performed a warm-up (walk, trot, and canter) and exercise test (walk, trot, canter, and gallop [90% to 100% maximum oxygen consumption [{VO(2)max}]) with measurements of LiDCO and FickCO obtained simultaneously after 60 seconds at each exercise level, for a total of 7 measurements. In part 2 of the study, 8 horses performed a warm-up (walk...
Clinical pathology in the racing horse: the role of clinical pathology in assessing fitness and performance in the racehorse.
The Veterinary clinics of North America. Equine practice    July 26, 2008   Volume 24, Issue 2 405-vii doi: 10.1016/j.cveq.2008.03.001
McGowan C.Clinical pathology is frequently used in racehorses to screen for "fitness" to race and to screen for disease that may affect performance. The role of clinical pathology in exercise testing of racehorses is important, especially in the area of blood lactate responses to exercise. This article discusses the use of resting and dynamic clinical pathology in the racehorse, especially in respect to investigation of the state of training (or fitness) and detection of subclinical performance-limiting disease.
High-intensity exercise induces structural, compositional and metabolic changes in cuboidal bones–findings from an equine athlete model.
Bone    June 19, 2008   Volume 43, Issue 4 724-733 doi: 10.1016/j.bone.2008.06.003
Tidswell HK, Innes JF, Avery NC, Clegg PD, Barr AR, Vaughan-Thomas A, Wakley G, Tarlton JF.Fatigue fracture of cuboidal bones occurs in the human foot as well as the equine carpus. The racehorse provides a naturally-occurring model to study the effects of high-intensity exercise on the morphology and metabolism of cuboidal bones. We studied both the mineral and the collagenous matrix of the third (C(3)) and radial (C(r)) carpal bones of raced and non-raced Thoroughbred (TB) horses. We hypothesised that racehorses would show increases in the mineral component of these bones and post-translational modifications of the collagenous matrix alongside changes in markers of collagen remodel...
Echocardiographic measurements of cardiac dimensions in normal Standardbred racehorses.
Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology    June 3, 2008   Volume 10, Issue 1 45-51 doi: 10.1016/j.jvc.2008.04.002
Zucca E, Ferrucci F, Croci C, Di Fabio V, Zaninelli M, Ferro E.The aim of this study was to obtain echocardiographic measurements and establish reference ranges for 14 parameters in Standardbred racehorses in training. Background: Several studies have been published about cardiac measurements in Thoroughbreds, Standardbreds, National Hunt horses, Warmbloods and ponies; however, not all parameters have been published for the Standardbred trotter in training. Methods: Thirty normal Standardbred racehorses in training were assessed by two-dimensional echocardiography (2-D) and M-mode echocardiography using standardized imaging planes. Mean values, standard d...
Effects of exercise vs experimental osteoarthritis on imaging outcomes.
Osteoarthritis and cartilage    May 27, 2008   Volume 16, Issue 12 1519-1525 doi: 10.1016/j.joca.2008.04.015
Kawcak CE, Frisbie DD, Werpy NM, Park RD, McIlwraith CW.To identify changes in imaging outcomes in a controlled model of osteoarthritis (OA) vs exercise. Methods: Sixteen 2-year-old horses were randomly assigned to an exercise control (n=8) or an exercise OA (n=8) group. All horses had middle carpal joints arthroscopically explored and an osteochondral fragment was induced in one middle carpal joint of the OA group. All horses were treadmill exercised for the duration of the study (91 days). Clinical, radiographic, nuclear scintigraphic, computed tomographic and magnetic resonance imaging (MRI) examinations were performed and outcomes of these were...
Pulmonary dysfunction and skeletal muscle changes in horses with RAO.
Journal of veterinary internal medicine    May 24, 2008   Volume 22, Issue 4 1014-1021 doi: 10.1111/j.1939-1676.2008.0111.x
Gehlen H, Oey L, Rohn K, Bilzer T, Stadler P.Chronic pulmonary diseases (recurrent airway obstruction [RAO]) have been reported to alter skeletal muscle cells in humans. The purpose of this study was to evaluate a potential relationship between pulmonary and muscle variables in horses with a clinical diagnosis of RAO. Muscle biopsies from healthy horses and from horses with RAO were investigated and the relationship between the severity of lung disease and the degree of muscular changes was determined. Objective: We hypothesized that chronic pulmonary disease can lead to changes of the skeletal muscle in horses. Methods: Fifteen healthy ...
Exercise induced stress in horses: selection of the most stable reference genes for quantitative RT-PCR normalization.
BMC molecular biology    May 19, 2008   Volume 9 49 doi: 10.1186/1471-2199-9-49
Cappelli K, Felicetti M, Capomaccio S, Spinsanti G, Silvestrelli M, Supplizi AV.Adequate stress response is a critical factor during athlete horses' training and is central to our capacity to obtain better performances while safeguarding animal welfare. In order to investigate the molecular mechanisms underlying this process, several studies have been conducted that take advantage of microarray and quantitative real-time PCR (qRT-PCR) technologies to analyse the expression of candidate genes involved in the cellular stress response. Appropriate application of qRT-PCR, however, requires the use of reference genes whose level of expression is not affected by the test, by ge...
Intralesional injection of platelet-rich plasma followed by controlled exercise for treatment of midbody suspensory ligament desmitis in Standardbred racehorses.
Journal of the American Veterinary Medical Association    May 16, 2008   Volume 232, Issue 10 1515-1520 doi: 10.2460/javma.232.10.1515
Waselau M, Sutter WW, Genovese RL, Bertone AL.To determine outcome of Standardbred racehorses with moderate to severe midbody suspensory ligament desmitis (MSD) treated by means of ultrasound-guided intralesional injection of a single dose of platelet-rich plasma (PRP) followed by a program of gradually increased exercise. Methods: Nonrandomized clinical trial. Methods: 9 Standardbred racehorses. Methods: Following injection of PRP, horses were allowed a controlled, gradual return to exercise. Race records for the year prior to injury and for 3 consecutive years after horses returned to racing were reviewed. For comparison purposes, race ...
Effects of warm-up intensity on oxygen transport during supramaximal exercise in horses.
American journal of veterinary research    May 2, 2008   Volume 69, Issue 5 690-696 doi: 10.2460/ajvr.69.5.690
Mukai K, Hiraga A, Eto D, Takahashi T, Hada T, Tsubone H, Jones JH.To determine whether warm-up exercise at different intensities alters kinetics and total contribution of aerobic power to total metabolic power in subsequent supramaximal exercise in horses. Methods: 11 horses. Methods: Horses ran at a sprint until fatigued at 115% of maximal oxygen consumption rate (VO(2max)), beginning at 10 minutes following each of 3 warm-up protocols: no warmup (NoWU), 1 minute at 70% VO(2max) (moderate-intensity warm-up [MoWU]), or 1 minute at 115% VO(2max) (high-intensity warm-up [HiWU]). Cardiopulmonary and blood gas variables were measured during exercise. Results: Th...
Activity of selected rostral and caudal hyoid muscles in clinically normal horses during strenuous exercise.
American journal of veterinary research    May 2, 2008   Volume 69, Issue 5 682-689 doi: 10.2460/ajvr.69.5.682
Morello SL, Ducharme NG, Hackett RP, Warnick LD, Mitchell LM, Soderholm LV.To determine the phase and quantitate the electromyographic (EMG) activity of the genioglossus, geniohyoideus, hyoepiglotticus, omohyoideus, sternohyoideus, sternothyroideus, and thyrohyoideus muscles of clinically normal horses during strenuous exercise. Methods: 7 clinically normal adult horses (2 Thoroughbreds and 5 Standardbreds). Methods: Bipolar electrodes were surgically implanted in the aforementioned muscles, and horses were subjected to an incremental exercise test on a high-speed treadmill. The EMG, heart rate, respiratory rate, and static pharyngeal airway pressures were measured d...
Changes in synovial fluid and serum biomarkers with exercise and early osteoarthritis in horses.
Osteoarthritis and cartilage    April 28, 2008   Volume 16, Issue 10 1196-1204 doi: 10.1016/j.joca.2008.03.008
Frisbie DD, Al-Sobayil F, Billinghurst RC, Kawcak CE, McIlwraith CW.To discriminate between changes in biomarkers with exercise compared to changes in biomarkers with osteoarthritis (OA) in exercising horses. Methods: Sixteen, 2-year-old horses were randomly assigned either to an exercise-alone (n=8) or OA-affected (also exercised) (n=8) group. All horses had both mid-carpal joints arthroscoped and OA induced in one mid-carpal joint in the OA-affected joints of OA-affected horses. Two weeks after surgery all horses commenced a strenuous exercise program on a high-speed treadmill. Clinical outcomes and synovial fluid and serum biomarkers, were evaluated weekly....
Dietary energy source affects glucose kinetics in trained Arabian geldings at rest and during endurance exercise.
The Journal of nutrition    April 22, 2008   Volume 138, Issue 5 964-970 doi: 10.1093/jn/138.5.964
Treiber KH, Geor RJ, Boston RC, Hess TM, Harris PA, Kronfeld DS.Advances in modeling and tracer techniques provide new perspective into glucose utilization and potential consequences to health or exercise performance. This study used stable isotope and compartmental modeling to evaluate how adaptation to a feed high in sugar and starch (SS) compared with a feed high in fat and fiber (FF) affects glucose kinetics at rest and during exercise in horses. Six trained Arabians adapted to each feed underwent similar tests at rest and while running approximately 4 m/s on a treadmill. For both tests, horses received 100 micromol/kg body weight [6,6-(2)H]glucose thr...
[Influence of subclinical pulmonary findings on cardiac parameters in Icelandic horses].
Berliner und Munchener tierarztliche Wochenschrift    April 17, 2008   Volume 121, Issue 3-4 137-144 
Gehlen H, Haubold A, Rohn K, Stadler P.In the present study we examined, if in Icelandic horses an increase in heart and/ or breathing rate is physiological and breed dependend or a sign of a pulmonary or cardiac disease. Therefore we examined 37 Icelandic horses with the prereport of being healthy. During clinical lung examination four horses showed symptoms of a pulmonary disease like increased breathing rate and enforced breathing at rest. These horses were excluded from the study. The other 33 horses were clinically normal. 17 of these horses were unridden (untrained) and 16 horses were regularly worked (trained). After clinica...
The pathobiology of exercise-induced superficial digital flexor tendon injury in Thoroughbred racehorses.
Veterinary journal (London, England : 1997)    April 10, 2008   Volume 181, Issue 2 79-89 doi: 10.1016/j.tvjl.2008.02.009
Patterson-Kane JC, Firth EC.Despite the high incidence of superficial digital flexor tendon (SDFT) injury in racehorses, the pathobiology of the condition is not clearly defined. The SDFT improves locomotor efficiency by storing elastic energy, but as a result it has low mechanical safety margins. As with the Achilles tendon in humans, rupture during athletic activity often follows accumulation of exercise and age-induced degenerative change that is not repaired by tenocytes. There is limited understanding of tenocyte biology and pathology, including responses to high mechanical strains and core temperatures during exerc...
Plasma concentration of leptin and ghrelin in Standardbred foals as related to the age, sex, exercise and training.
Animal : an international journal of animal bioscience    April 1, 2008   Volume 2, Issue 4 582-587 doi: 10.1017/S1751731108001638
Kędzierski W, Kapica M.The effect of acute exercise was studied in a group of 42 clinically healthy young Standardbred trotters. These trotters had been divided into four groups according to their age. Their ages were from 1.5 to 3 years. Three jugular venous blood samples were collected via venipuncture from each horse. These samples were collected while (1) at rest, (2) after the end of the exercise and (3) 30 min after the end of the exercise. Exercise showed a significant increase in plasma leptin concentration (3.8 ± 0.31 at rest v. 4.3 ± 0.37 just after exercise and 4.4 ± 0.47 ng/ml after a 30-min rest; ANO...
Unexplained underperformance syndrome in sport horses: classification, potential causes and recognition.
Equine veterinary journal    March 22, 2008   Volume 40, Issue 6 611-618 doi: 10.2746/042516408X299118
Rivero JL, van Breda E, Rogers CW, Lindner A, van Oldruitenborgh-Oosterbaan MM.When inadequate training stress is applied and recovery time is insufficient, performance reduction and chronic maladaptation occurs. Known as overtraining syndrome (OTS), this complex condition afflicts horses in top training. The name of the syndrome implies causation and it is necessary to differentiate it from over-reaching, a term used in horses that, after suffering a loss of performance without an obvious clinical reason, recover their performance within 1 or 2 weeks. The term OTS should be used for horses in heavy training losing performance without an obvious clinical reason and which...
The effect of early training and the adaptation and conditioning of skeletal tissues.
The Veterinary clinics of North America. Equine practice    March 4, 2008   Volume 24, Issue 1 37-51 doi: 10.1016/j.cveq.2007.11.005
Smith RK, Goodship AE.Horses as equine athletes must be conditioned and trained to optimize the whole animal for the particular type of athletic activity. An extremely high proportion of all injuries in the equine athlete in general, and in the racehorse in particular, are associated with the skeletal system, many of which are believed to arise from a mismatch between the prevailing exercise levels and adaptation. To maximize performance, yet minimize injury, it is important to understand and apply the principles of functional adaptation of the component tissues of the skeletal system (bone, cartilage, tendons, and...
Multiple pathways to osteoarthritis and articular fractures: is subchondral bone the culprit?
The Veterinary clinics of North America. Equine practice    March 4, 2008   Volume 24, Issue 1 101-116 doi: 10.1016/j.cveq.2007.12.001
Cruz AM, Hurtig MB.Osteoarthritis and articular fractures are commonly responsible for early retirement from athletic performance. The subchondral bone (SCB) in those conditions is being recognized as an integral component in their pathophysiology. Early recognition of these potentially career-ending diseases may require understanding of the progression of changes occurring in SCB with time and exercise.
High-speed gallop locomotion in the Thoroughbred racehorse. II. The effect of incline on centre of mass movement and mechanical energy fluctuation.
The Journal of experimental biology    March 4, 2008   Volume 211, Issue Pt 6 945-956 doi: 10.1242/jeb.006692
Parsons KJ, Pfau T, Ferrari M, Wilson AM.During locomotion on an incline, mechanical work is performed to move an animal up the slope and increase the potential energy (PE) of the trunk and hence the centre of mass (CoM). Thus, at a given speed the total net mechanical work increases with the PE of the animal. In this study we investigate the mechanical energy (ME) fluctuations and the mechanical cost of transport (MCT) in six horses galloping up a range of gradients. We captured trunk movement with a six degrees-of-freedom inertial sensor mounted over the dorsal spinous process of the fourth to sixth thoracic vertebrae of the horse....
Epidemiology of racetrack injuries in racehorses.
The Veterinary clinics of North America. Equine practice    March 4, 2008   Volume 24, Issue 1 1-19 doi: 10.1016/j.cveq.2007.11.003
Parkin TD.This article describes the development of epidemiologic analyses of racetrack injury in racehorses. The risk or rate of fatal and nonfatal injury in racing and training around the world is examined. The focus is on the importance of global collaboration and the identification of modifiable risk factors. In particular, exercise-related risk factors for injury are evaluated and the potential impact of interventions discussed.
Embryo recovery from exercised mares.
Animal reproduction science    January 20, 2008   Volume 110, Issue 3-4 237-244 doi: 10.1016/j.anireprosci.2008.01.015
Mortensen CJ, Choi YH, Hinrichs K, Ing NH, Kraemer DC, Vogelsang SG, Vogelsang MM.The effect of exercise on mare reproductive efficiency was evaluated by comparing rates of embryo recovery from mares assigned to either an exercise regimen or a non-exercise (control) regimen. Exercised mares were worked daily for 30 min under average ambient conditions of >30 degrees C and >50% humidity. Mares were inseminated during estrus and subjected to uterine flush for embryo recovery on d 7 after ovulation for two consecutive cycles. After this, mares were allocated to the opposite group and allowed an estrous cycle without reproductive manipulation; then insemination and uterin...
Lameness, athletic performance, and financial returns in yearling Thoroughbreds bought for the purpose of resale for profit.
Journal of the American Veterinary Medical Association    January 3, 2008   Volume 232, Issue 1 85-90 doi: 10.2460/javma.232.1.85
Preston SA, Trumble TN, Zimmel DN, Chmielewski TL, Brown MP, Hernandez JA.To characterize lameness during training and compare exercise variables and financial returns among yearling Thoroughbreds that were bought for the purpose of resale for profit. Methods: 40 yearling Thoroughbreds. Methods: Prospective study. Methods: Horses purchased at yearling sales (summer 2004) were trained prior to resale at 2-year-olds in training sales (spring 2005). Horses were monitored daily for diagnosis and treatment of lameness during training. Selected variables, including sex, age, purchase price, lameness, distance (No. of furlongs) galloped during training, and financial retur...
Evaluation of a new strategy to modulate skeletal development in Thoroughbred performance horses by imposing track-based exercise during growth.
Equine veterinary journal    December 21, 2007   Volume 40, Issue 2 111-118 doi: 10.2746/042516408X268923
Rogers CW, Firth EC, McIlwraith CW, Barneveld A, Goodship AE, Kawcak CE, Smith RK, van Weeren PR.No data exist on the intensity of exercise required or on possible harmful effects of increasing exercise in foals over the natural level when free at pasture. Objective: To investigate whether an increase in workload over free pasture exercise in the period from directly after birth to the start of training is tolerated by Thoroughbred (TB) foals without increasing injury rate or producing other undesired side effects. Methods: Thirty-three TB foals were allocated to one of 2 exercise groups directly after birth. One group (PASTEX) was raised on pasture and the other (CONDEX) kept under ident...
Early exercise advances the maturation of glycosaminoglycans and collagen in the extracellular matrix of articular cartilage in the horse.
Equine veterinary journal    December 21, 2007   Volume 40, Issue 2 128-135 doi: 10.2746/042516408X253091
van Weeren PR, Firth EC, Brommer H, Hyttinen MM, Helminen AE, Rogers CW, Degroot J, Brama PA.Training at a very young age may influence the characteristics of the collagen network of articular cartilage extracellular matrix (ECM) in horses. Objective: To investigate whether increasing workload of foals results in significant changes in the biochemical composition of articular cartilage ECM. Methods: Thoroughbred foals (n = 33) were divided into 2 different exercise groups from age 10 days-18 months. One group (PASTEX; n = 15) was reared at pasture; the other (CONDEX; n = 18) underwent a specific additional training programme that increased workload by 30%. At mean age 18 months, 6 ani...
Evaluation of a new strategy to modulate skeletal development in racehorses by imposing track-based exercise during growth: the effects on 2- and 3-year-old racing careers.
Equine veterinary journal    December 21, 2007   Volume 40, Issue 2 119-127 doi: 10.2746/042516408X266088
Rogers CW, Firth EC, McIlwraith CW, Barneveld A, Goodship AE, Kawcak CE, Smith RK, van Weeren PR.No data exist on the effects of conditioning exercise at foal age on workload and subsequent clinical injury rate during their 2- and 3-year-old racing careers. Objective: To investigate the effects of subjecting TB foals to conditioning exercise prior to the start of race training on: the workload required to reach a level of fitness sufficient to compete; and the prevalence of orthopaedic injury during the first 2 seasons of their racing careers. Methods: Twenty 18-month-old TBs, 12 subjected to conditioning exercise at foal age (CONDEX) and 8 exercised spontaneously at pasture only (PASTEX)...
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