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Topic:Horses
"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
[Structure and topography of the nucleus proprius cornus dorsalis of the spinal cord of horses]. The studies performed on spinal cords of two horses revealed that cells of the nucleus of the own dorsal horn are present in all segments of lumbo-sacral part of the spinal cord. The nucleus is composed of two parts: basal and marginal. Basal part is composed of large and medium size cells situated in 2/3 of the lower part of the grey substance of the dorsal horn. The marginal part of the described nucleus is composed of elongated and spindle shaped cells situated along the dorsal margine of the grey substance of the dorsal horn. Continuity of the nucleus in lumbo-sacral part of the spinal cor...
Thoracic limb digital extensor denervation in young horses. Low radial neurectomy in the left thoracic limb was performed in 4 mixed-breed weanling horses, with subsequent paralysis of the lateral and common digital extensor muscles. Weight bearing of the denervated and control limbs was discouraged by the use of special shoeing. Clinical signs of flexural deformity were not induced in the horses.
Phalangeal and navicular bone hypoplasia and hoof malformation in the hind limbs of a foal. Anatomical anomalies in the hind feet of a seven month old Appaloosa foal were identified and investigated through the use of gross anatomical dissection, radiography and angiography. Abnormalities were restricted to the distal aspect of both hind legs, the right hind leg being more severely affected. Anatomically the right foot resembled that of an equine fetus of approximately 120 days gestational age. Disruption of vascular perfusion to hoof structures was evident in both hind legs and was related to areas of abnormal bone conformation as well as to areas of abnormal ossification and calcif...
Antistreptolysin O titer in horses. Antistreptolysin O (ASO) titers were determined in the sera of 532 horses from stud farms and 436 working horses from small farms. A statistically significant correlation was seen between the ASO titer and the age of the horses. There was a significant difference between mean ASO titer in horses 0-2 years and horses 2-10 years In horses older than 10 years the titer was significantly higher than mean ASO titer for the group. Twenty four of 30 horses in which ASO titer was higher or equal to 80 I.U. had histories which suggested that streptococcal infection had occurred. Clinical and bacteriolo...
Effect of laryngeal hemiplegia and laryngoplasty on airway flow mechanics in exercising horses. The effect of left laryngeal hemiplegia on airway flow mechanics in 5 exercising horses was examined, and the efficacy of surgical repair by prosthetic laryngoplasty was evaluated. Measurements of the upper airway flow mechanics were made with horses on a treadmill (incline 6.38 degrees) while standing (period A); walking at 1.3 m/s (period B); trotting at 2.6 m/s (period C); trotting at 4.3 m/s (period D); and standing after exercise (period E). Experiments were done on healthy horses before any surgical manipulation (control), at 10 days after left recurrent laryngeal neurectomy, and at leas...
The use of atropine to control heart rate responses during detomidine sedation in horses. Detomidine is a sedative-analgesic which has a pharmacological profile similar to xylazine. There is evidence that the sedative effects are mediated through alpha-2 adrenoceptors. Cardiopulmonary responses were determined using detomidine as the principal agent and as a preanesthetic prior to the induction of general anesthesia. Compatibility with guaifenesin, sodium thia-mylal and halothane were determined. As in the case of xylazine, detomidine produces a slowing of heart rates. This was found to be either sinus bradycardia or heart block. There may be a corresponding increase in systolic bl...
Segregation distortion within the equine MHC; analogy to a mouse T/t-complex trait. Segregation distortion was found for a haplotype of the equine lymphocyte antigen (ELA) system in an extended family of American Standardbred horses. In one sire family, consisting of a stallion and his 17 sons and grandsons, the gene for ELA-A10 (A10) was transmitted to 57.7% of 638 offspring scored (P = 0.001). Significant segregation distortion was not seen for mares or for unrelated stallions, regardless of the ELA markers they possessed. Since the effect was seen for this one sire family and not seen for other stallions with A10, it is unlikely that the gene for A10 is the cause of this p...
DNA polymorphism in the major histocompatibility complex of man and various farm animals. In the past few years it has been possible by combining enzymatic cleavage of genomic DNA and the Southern blot hybridization technique to explore the endonuclease recognition site polymorphism of the MHC. HLA class I and DR and DQ alpha and beta class II specific probes as well as human C4 and Bf class III probes were used. All these probes were shown to cross-hybridize with DNA from pigs, cattle, sheep and horses. Hybridization of human genomic DNA with a class I probe showed 15-25 bands per genome depending on the enzyme used. Distinct endonucleases generated clusters of restriction fragmen...
Salmonella serotypes from animals in New York State, 1978-1983. The salmonella serotypes isolated during 1978 to 1983 at the diagnostic and clinical laboratories of the New York State College of Veterinary Medicine from animal sources in New York state were reviewed and compared to earlier data from New York state animals and to national data for both human and animal sources. A total of 255 salmonella strains were studied from the six year period and included 33 serotypes. Salmonella enteritidis ser Typhimurium continued to be the most commonly reported serotype followed by serotype Anatum. Generally serotypes from New York state animals reflected nationa...
Identification of betamethasone and a major metabolite in equine urine. Betamethasone and its major unconjugated metabolite, 6-beta-hydroxybetamethasone, were detected in equine urine by thin-layer chromatography and characterized by micro-liquid chromatography/mass spectrometry (micro-LC/MS). Their structures were confirmed by a combination of infrared spectroscopy and nuclear magnetic resonance spectroscopy.
An apparatus for collecting blood samples by radiotelemetry from horses during exercise. An apparatus was designed to collect four consecutive blood samples from exercising horses. The collection of each sample was controlled by valves activated by radiotelemetry signals transmitted by an observer. Using the device, venous blood samples were collected from ten thoroughbred racehorses before, during and after a 400 m training gallop. Blood glucose increased markedly post-exercise. Both phosphorus and potassium concentrations increased during exercise, decreased post-exercise and recovered to pre-exercise levels within 120 minutes. The system was modified to collect anaerobic sample...
The interaction between some serine proteinases and horse leucocyte inhibitor. Horse blood leucocyte cytosol exhibits a broad inhibitory activity against serine proteinases. The purified inhibitor was exposed to investigated enzymes (trypsin, chymotrypsin, elastases and serine proteinase from S. aureus) for variable time and the products were analyzed by gradient polyacrylamide gel electrophoresis in the presence of sodium dodecyl sulphate. The molar ratio I:E, association rate constants k on and inhibition constants Ki for the enzymes and inhibitor were determined. The examined elastases form stable, stoichiometric complexes with the inhibitor (Ki less than 10(-10) M), ...
Comparative scanning electron-microscopic study of the lingual papillae in two species of domestic mammals (Equus caballus and Bos taurus). 1. Gustatory Papillae. The morphological characteristics of bovine and equine gustatory lingual papillae are compared by scanning electron microscopy. The fungiform papillae in the cow have a shape that corresponds to their name, while in the horse, they almost do not emerge from the surface of the tongue. These papillae show taste pores in both species. The vallate papillae, four times larger in the horse than in the cow, show a complex organization of papillae and secondary grooves in the horse. In the cow, they occur single and are surrounded by a thick annular pad of lingual mucosa. Taste pores have been observe...
Limits to exercise performance: some ideas from comparative studies. Examples of exercise performance and metabolic scope in non-human mammalian species are considered from the point of view of problems and questions which may provide insights into evolutionary processes influencing adaptations to muscular activity. Consideration of both aerobic and anaerobic performance is required. Some recent approaches, notably that concerned with the concept of symmorphosis, the integration of design for the accommodation of variations in activity, show promise of new ways for comparative investigations of the adjustments to exercise.
Isolation of meclofenamic acid and two metabolites from equine urine–a comparison between horse and man. Two metabolites of meclofenamic acid have been isolated from equine urine. Both metabolites are found to be monohydroxylated forms of meclofenamic acid by gas chromatography-mass spectrometry after extractive alkylation. The parent drug and the metabolites are separated by reversed-phase liquid chromatography on a Spherisorb ODS column, using methanol-phosphate buffer eluents and UV detection at 280 nm. The structure of the metabolites is discussed on the basis of LC, TLC and GC-MS data.
Comparison of specificity of human and horse leucocyte proteinases with synthetic peptide substrates. Highly purified horse leucocyte proteinases 1, 2A and 2B hydrolyze synthetic substrates which are decomposed also by human leucocyte elastase but they are unable to hydrolyze typical substrates of cathepsin G. Thus in distinction to other mammalian species horse leucocytes are devoid of cathepsin G and contain only elastases.
Heredity of navicular disease. Bone structure, nutrient canals, form and definition, and a total evaluation of both fore navicular bones were radiologically evaluated in 169 three- and four-year-old Dutch warmblood mares divided into eleven daughter (half sister) groups. On the basis of the 'total evaluation', differences between the three- and four-year-old horses were detectable. Using the 'total evaluation', significant differences were found between daughter groups consisting of three-year-old mares. These differences support the theory that podotrochleosis may be (partly) due to the presence of genetic factors. The pos...
Equine herpesvirus type 1 (EHV-1) induced abortions and paralysis in a Lipizzaner stud: a contribution to the classification of equine herpesviruses. Out of 30 cases of abortion and perinatal deaths in a Lipizzaner stud in Austria 10 mares died after having shown central nervous system disturbances, ataxias and paralysis. The etiological agent of this "abortion storm" was equine herpesvirus type 1 (EHV-1). The restriction enzyme pattern of the DNA from 5 isolates recovered from fetuses has been analyzed and compared with the known reference strains of EHV-1, -2, -4 and an Austrian vaccine strain. The DNA restriction profiles of the Lipizzaner isolates as well as of the vaccine strain could be identified as being typical of abortigenic strai...
The distribution of inhibited early third stage Cyathostominae larvae in the large intestine of the horse. The distribution of inhibited early third stage Cyathostominae larvae in different parts of the large intestine of the horse was studied in 20 Shetland ponies necropsied in autumn 1982, 1983 and 1984. The location of the larvae in the large intestinal wall was studied by histological examination of the intestines of the eight ponies from 1984. Inhibited larvae were located predominantly and more or less equally in the caecum and the ventral colon. Generally fewer early L3 were in the dorsal colon. In 1984 a considerable proportion (mean 17%, range 9.7-36.9%) of the inhibited larvae was found i...
Dose-related effects of ethylketazocine on nociception, behaviour and autonomic responses in the horse. Sensitive methods for measuring the analgesic, physiological and behavioural effects of opioids in the horse have recently been developed. Fentanyl, a prototypic mu-opiate receptor agonist, has been previously shown to produce a syndrome characterized by marked analgesia and locomotor stimulation as well as tachycardia, tachypnoea and behavioural arousal. To determine whether other opiate receptors mediate some of the actions of the narcotic analgesics in the horse, an agent with activity at kappa- and to lesser extent mu-receptors was studied using a vigorous experimental protocol. Like fenta...
