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Topic:Horses

"Horses" is a broad topic that encompasses various aspects of equine biology, behavior, and management. This category includes studies on the anatomy, physiology, and genetics of horses, as well as their behavior, nutrition, and care. Research in this area may also cover the historical and cultural significance of horses, their roles in agriculture, sport, and therapy, and the challenges associated with their conservation and welfare. The page aggregates peer-reviewed research articles and scholarly studies that explore the multifaceted relationships between humans and horses, examining both scientific and socio-economic perspectives.
Three-dimensional kinematic technique for evaluation of horse locomotion in outdoor conditions.
Medical & biological engineering & computing    May 1, 1996   Volume 34, Issue 3 249-252 doi: 10.1007/BF02520082
Degueurce C, Dietrich G, Pourcelot P, Denoix JM, Geiger D.No abstract available
Minor constituents of sabulous material in equine urine.
Research in veterinary science    May 1, 1996   Volume 60, Issue 3 238-242 doi: 10.1016/s0034-5288(96)90046-6
Díaz-Espiñeira M, Escolar E, Bellanato J, Rodriguez M.The secondary constituents accompanying calcite and vaterite (crystalline forms of calcium carbonate) in the sabulous deposits from 140 vesical samples and one renal sample of equine urine were studied by infrared spectroscopy (IR), scanning electron microscopy (SEM) and energy dispersive X-ray analysis (EDX). Apatitic calcium phosphate, present in 12 per cent of the samples, generally appeared in the form of spherulites with smooth and rough surfaces. Calcium sulphate, clearly detected by IR in 12.7 per cent of the samples, did not have a characteristic structure under SEM, although EDX detec...
Immunohistochemical detection of virulence-associated antigens of Rhodococcus equi in pulmonary lesions of foals.
Veterinary pathology    May 1, 1996   Volume 33, Issue 3 341-343 doi: 10.1177/030098589603300312
Madarame H, Takai S, Morisawa N, Fujii M, Hidaka D, Tsubaki S, Hasegawa Y.Rhodococcus equi was isolated from the lungs of six foals with bronchopneumonia. All isolates expressed 15-17-kd antigens by immunoblot analysis and contained a virulence-associated plasmid of 85 or 90 kb. Immunohistochemically, R. equi from all pulmonary lesions showed the expression of 15-17-kd antigens mainly in the phagocytic cells. The specific monoclonal antibody to 15-17-kd antigens of R. equi (MAb 10G5) may be an aid in the diagnosis of R. equi-induced pneumonia.
Control of Babesia equi parasitemia.
Parasitology today (Personal ed.)    May 1, 1996   Volume 12, Issue 5 195-198 doi: 10.1016/0169-4758(96)10007-7
Knowles DP.Infection of horses with the hemoprotozoan Babesia equi has been reported in southern Florida, US Virgin Islands, part of Asia, Russia, India, the Middle East, Europe, Africa, Australia, South America, Central America, Mexico, Philippine Islands and some Caribbean islands. The restrictions placed on the international movement of infected horses has refocused attention on potential methods to control or eliminate infection. Don Knowles here discusses the primary chemotherapeutic compounds that have been used; the current knowledge concerning immune responses that potentially contribute to contr...
Quantitative characterization of lymphocyte populations in bronchoalveolar lavage fluid and peripheral blood of normal adult Arabian horses.
Veterinary immunology and immunopathology    May 1, 1996   Volume 51, Issue 1-2 29-37 doi: 10.1016/0165-2427(95)05510-x
Hines MT, Palmer GH, Byrne KM, Brassfield AL, McGuire TC.Bronchoalveolar lavage fluid (BALF) and peripheral blood were obtained from each of 17 adult Arabian mares and absolute numbers and relative lymphocyte proportions were determined for total T lymphocytes, using CD2 as a marker, CD4 + T lymphocytes, CD8 + T lymphocytes, CD5 + lymphocytes, and sIgM + B lymphocytes. The marked variation in BALF cell recovery resulted in wide variation in absolute values for each lymphocyte subset. The relative proportions of gated BALF lymphocytes were much less variable and provided a basis for comparison of lymphocyte subsets between the BALF and peripheral blo...
Application of a hook plate for management of equine ulnar fractures.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 207-212 doi: 10.1111/j.1532-950x.1996.tb01400.x
Murray RC, Debowes RM, Gaughan EM, Bramlage LR.Closed fractures of the proximal aspect of the ulna were repaired in 10 horses younger than or equal to 6 months of age by application of a hook plate using a tension band principle. Ulnar fractures were classified as type 1A (2 horses), type 1B (4 horses), type 2 (1 horse), type 3 (1 horse), and type 4 (2 horses); all fractures had displacement of a proximal fragment. Complications were implant deformation (4 horses), screw pullout (1 horse), osseous sequestration (1 horse), ulnar fracture through a hole used to apply a tension device (1 horse), and metacarpophalangeal deformity associated wi...
Novel approaches to the purification and identification of cytochrome P450 enzymes in the equine.
Biochemical Society transactions    May 1, 1996   Volume 24, Issue 2 208S doi: 10.1042/bst024208s
Byard J, Marshall DE, Houghton E, Gower DB.No abstract available
Effect of vaccination of ponies with A4 anti-idiotypic antibody on serum idiotype (1C9) and antilipid A concentration.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 655-658 
BonenClark GD, MacKay RJ, Ward RE, Sheerin B.To evaluate the humoral response of horses to vaccination, using a murine monoclonal anti-idiotypic antibody (A4) that shares an epitope with lipid A. Methods: Serum concentrations of antilipid A antibody and 1C9 (epitope on murine monoclonal antilipid A antibody) were measured serially during the period of vaccination with A4. Methods: 6 clinically normal adult ponies. Methods: Ponies were inoculated IM 3 times at monthly intervals with A4. Two weeks after each inoculation, serum was obtained and was assayed by ELISA for antilipid A and 1C9 concentrations. Additional vaccinations were given t...
Mummified fetus in a mare.
Journal of the American Veterinary Medical Association    May 1, 1996   Volume 208, Issue 9 1438-1440 
Barber JA, Troedsson MH.A 12-year-old Arabian mare with a history of repeated early embryonic losses gave birth to a mummified fetus. The fetus was not the result of a pregnancy with twins. The mare had been given a progestogen throughout gestation and expelled the mummified fetus at about 325 days of gestation, 2 weeks after progestogen treatment was discontinued. We estimate that the size of the fetus was consistent with a fetal age of 5 months. The mare and mummified fetus illustrated that progestogen administration after 100 days of gestation can promote retention of a nonviable fetus. When the fetoplacental unit...
Metacarpophalangeal joint synovial pad fibrotic proliferation in 63 horses.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 199-206 doi: 10.1111/j.1532-950x.1996.tb01399.x
Dabareiner RM, White NA, Sullins KE.Medical records, radiographs, and sonograms of 63 horses with metacarpophalangeal joint synovial pad proliferation were examined retrospectively. All horses had lameness, joint effusion, or both signs associated with one or both metacarpophalangeal joints. Bony remodeling and concavity of the distodorsal aspect of the third metacarpal bone (Mc3) just proximal to the metacarpal condyles was identified by radiography in 71 joints (93%); 24 joints (32%) had radiographic evidence of a chip fracture located at the proximal dorsal aspect of the proximal phalanx. Fifty-four joints (71%) were examined...
Accessory ossification centres associated with osteochondral fragments in the extremities of horses.
Journal of comparative pathology    May 1, 1996   Volume 114, Issue 4 385-398 doi: 10.1016/s0021-9975(96)80014-4
Grøndahl AM, Jansen JH, Teige J.Fifty-six tarsocrural joints and 94 metatarsophalangeal joints were examined, at necropsy, from horses aged < or = 2 years. Osteochondral fragments at the cranial aspect of the intermediate ridge of the distal part of the tibia were seen in six horses, and at the proximoplantar aspect of the proximal phalanx in seven horses. Defects in the proximoplantar aspect of the proximal phalanx without osteochondral fragments were seen in a further two horses. Inflammatory and degenerative changes were not observed in any of the joints examined. From the incidence and natural course of these fragment...
Inhibition of the protease activity in tracheobronchial aspirates of horses with chronic obstructive pulmonary disease.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 603-607 
Koivunen AL, Maisi P, Fang W, Sandholm M.To clarify the role of proteolytic enzymes in the pathogenesis of chronic obstructive pulmonary disease (COPD) in horses, and to investigate new possibilities for treatment of this disease by interfering in the proteolytic process. Methods: Effect of antiproteolytic activity of selected protease inhibitors on tracheal aspirates was studied in vitro, and the inhibition profiles were compared with those of purified proteases. Methods: Respiratory tract secretions with antiproteolytic activity from 9 horses with COPD. Methods: Caseinolytic agar-diffusion assay. Results: The protease-inhibition pr...
Pericarditis and pleuritis caused by Mycoplasma felis in a horse.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 237-240 doi: 10.1111/j.2042-3306.1996.tb03779.x
Morley PS, Chirino-Trejo M, Petrie L, Krupka L, Schwab M.No abstract available
Expression of types II, VI and X collagen in equine growth cartilage during development.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 189-198 doi: 10.1111/j.2042-3306.1996.tb03772.x
Henson FMD, Davies ME, Schofield PN, Jeffcott LB.The synthesis and expression of collagen types II, VI and X were investigated in growth cartilage selected from a group of 31 horses and ponies in the age range 157 days of gestation to 12 years. Collagen isolation, immunolocalisation and in situ hybridisation techniques were used in order to provide information on the pattern of synthesis of these 3 collagens during endochondral ossification in normal horses. Type II collagen immunoreactivity and mRNA expression was found in each of the 3 zones of growth cartilage chondrocytes in all samples studied, whereas the localisation of both collagen ...
Development of subchondral cystic lesions after articular cartilage and subchondral bone damage in young horses.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 225-232 doi: 10.1111/j.2042-3306.1996.tb03777.x
Ray CS, Baxter GM, McILWRAITH CW, Trotter GW, Powers BE, Park RD, Steyn PF.The objective of this study was to determine if damage to the articular cartilage alone or articular cartilage plus subchondral bone of the distal medial femoral condyle of young, exercised horses resulted in the formation of subchondral cystic lesions. Twelve Quarter Horses (age 1-2 years), free of clinical and radiographic signs of osteochondrosis and lameness were used. In 6 horses (Group 1), a 15 times 1 mm linear full thickness defect in the articular cartilage was made arthroscopically on the weightbearing surface of the distal aspect of the medial femoral condyle. In the other 6 horses ...
Chylothorax due to primary thoracic haemangiosarcoma in a horse.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 241-244 doi: 10.1111/j.2042-3306.1996.tb03780.x
Brink P, Wilkins LP, Spano JS.No abstract available
Effects of U-74389G, a novel 21-aminosteroid, on small intestinal ischemia and reperfusion injury in horses.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 762-770 
Vatistas NJ, Snyder JR, Hildebrand SV, Harmon FA, Woliner MJ, Barry SJ, Nieto J, Henry P, Enos LR, Magliano D, Brown SA, Drake C.To determine the effects of the 21-aminosteroid, U-74389G, on reperfusion of the equine jejunum, using total (TVO) and partial (PVO) vascular occlusion during the ischemic period. Methods: TVO: 16 healthy horses were randomly allotted to 3 groups-4 horses received the vehicle alone, 6 horses received a low dosage (3 mg/kg o body weight), and 6 horses a high dosage (10 mg/kg) of U-7438G. PVO: 10 healthy horses were randomly allotted to 2 groups--5 horses received the vehicle alone, and 5 horses received the low dosage (3 mg/kg) of U-74389G. Methods: TVO was induced for 1 hour followed by 2 hour...
Effects of a combination of detomidine and butorphanol on respiratory function in horses with or without chronic obstructive pulmonary disease.
American journal of veterinary research    May 1, 1996   Volume 57, Issue 5 705-709 
Lavoie JP, Phan ST, Blais D.To evaluate the effects of detomidine and butorphanol in combination on respiratory function in horses and to determine whether these effects are more severe in horses with pre-existing respiratory dysfunction, Methods: Pulmonary function testing and arterial blood gas analyses were performed before and after administration of a combination of detomidine (10 micrograms/kg of body weight, i.v.) and butorphanol (20 micrograms/kg, i.v.). Methods: 5 horses with chronic obstructive pulmonary disease and 5 horses free of respiratory disease (controls). Methods: Flow rates were obtained from a pneumo...
Open peritoneal drainage in horses with experimentally induced peritonitis.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 189-194 doi: 10.1111/j.1532-950x.1996.tb01397.x
Chase JP, Beard WL, Bertone AL, Goltz K.Peritonitis was induced in 12 horses by median celiotomy and 1 hour of small intestinal ischemia. Six horses had primary closure of the incision, whereas six horses had a plastic mesh sutured to the ventral abdominal wall leaving the abdomen open for ventral drainage. The mesh was removed after 5 days and the abdominal wall was closed by apposition of the linea alba and subcutaneous tissues and approximation ef the skin edges. Peritoneal fluid was collected and analyzed for nucleated cell count and total protein concentration on days 0 and 5. Serum biochemical profiles, serum electrolyte conce...
Failure of β-carotene absorption negates any potential effect on ovarian function in mares.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 233-236 doi: 10.1111/j.2042-3306.1996.tb03778.x
Watson ED, Cí·¯ord D, Burger I.No abstract available
Pulmonary capillary pressure during exercise in horses.
Journal of applied physiology (Bethesda, Md. : 1985)    May 1, 1996   Volume 80, Issue 5 1792-1798 doi: 10.1152/jappl.1996.80.5.1792
Sinha AK, Gleed RD, Hakim TS, Dobson A, Shannon KJ.The object of this study was to relate pulmonary capillary pressure to arterial and wedge pressures during exercise. Pulmonary vascular pressures were measured in six standardbred horses exercising at speeds equivalent to 75, 90, and 100% of maximal heart rate. Vascular pressures were measured with transducer-tip catheters and expressed relative to esophageal pressure. Pulmonary capillary pressure was estimated by the arterial-occlusion technique modified for exercise. Mean pulmonary arterial, capillary and wedge pressures increased from 30.5 +/- 6.3, 17.8 +/- 4.3, and 13.4 +/- 1.6 mmHg, respe...
Mycoplasma infections in horses: a fresh look using modern methods may reveal an elusive ‘virus’.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 177-179 doi: 10.1111/j.2042-3306.1996.tb03770.x
Wood JLN, Chanter N.No abstract available
Equine adenocarcinomas of the large intestine with osseous metaplasia.
Journal of comparative pathology    May 1, 1996   Volume 114, Issue 4 451-456 doi: 10.1016/s0021-9975(96)80020-x
Kirchhof N, Steinhauer D, Fey K.Large intestinal adenocarcinoma with osseous metaplasia was diagnosed in two horses, a 15-year-old standard bred gelding and a 9-year-old Haflinger mare. Clinically, both animals had displayed weight loss and anaemia. A presumptive diagnosis of abdominal neoplasia was made and the horses were humanely killed. At necropsy, the gelding and the mare were found to have ulcerated tumours growing into the lumen of the caecum and colon, respectively. In the mare, the mass extended through the mesocolon and was evident in the left dorsal and ventral colon. Histopathologically, the tumours consisted of...
Immunotherapy trial for horses in British Columbia with Culicoides (Diptera:Ceratopogonidae) hypersensitivity.
Journal of medical entomology    May 1, 1996   Volume 33, Issue 3 458-466 doi: 10.1093/jmedent/33.3.458
Anderson GS, Belton P, Jahren E, Lange H, Kleider N.Immunotherapy was used to treat horses in British Columbia for Culicoides hypersensitivity. This is a severe, chronic, recurrent allergic disease of horses that results in severe irritation, large lesions, hair loss and secondary infection in the ventral midline, mane, and proximal region of the tail. A crude Culicoides extract was injected subcutaneously, in increasing doses, into 10 horses that were affected severely by the disease. Weekly doses reduced the clinical signs in 9 of the 10 horses in the 1st yr. Eight horses were treated with a maintenance dose during a 2nd yr. After the 2nd yr,...
Oxygen affinity and Bohr effect responses to 2,3-diphosphoglycerate in equine and human blood.
Research in veterinary science    May 1, 1996   Volume 60, Issue 3 272-275 doi: 10.1016/s0034-5288(96)90053-3
diBella G, Scandariato G, Suriano O, Rizzo A.The dependence of blood oxygen affinity and the Bohr effect on the concentration of 2,3-diphosphoglycerate (DPG) in erythrocytes was investigated in 24 trotter horses and 24 healthy men. The oxygen tension at half saturation and standard conditions (P50st at pH 7.4, PCO2(40) mmHg and 37 degrees C) and the carbon dioxide or fixed-acid-induced Bohr effect (dlogP50/dpH) were determined. Samples of fresh blood and blood depleted of or enriched with DPG were studied. In the absence of measurable DPG, the equine and human blood had similar mean (SD) values of P50st (16.6 [0.6] and 16.2 [0.7] mmHg, r...
Differences in quantitated electroencephalographic variables during surgical stimulation of horses anesthetized with isoflurane.
Veterinary surgery : VS    May 1, 1996   Volume 25, Issue 3 249-255 doi: 10.1111/j.1532-950x.1996.tb01409.x
Otto KA, Voight S, Piepenbrock S, Deegen E, Short CE.The effects of noxious surgical stimulation on the electroencephalogram (EEG) in 15 horses anesthetized with isoflurane were evaluated during orthopedic (group 1) and soft tissue (group 2) procedures. The quantitative EEG variables theta/delta ratio (T/D), alpha/delta ratio (A/D), beta/delta ratio (B/D), median power frequency (MED), and 80% spectral edge frequency (SEF 80) recorded during Surgeries at 1.7% end-tidal concentration of isoflurane (ET(iso)) were compared with values from five nonstimulated control horses anesthetized at 1,7% ET(iso). The EEG variables T/D, A/D, MED, and SEF 80 fr...
Simultaneous infusions of propofol and ketamine in ponies premedicated with detomidine: a pharmacokinetic study.
Research in veterinary science    May 1, 1996   Volume 60, Issue 3 262-266 doi: 10.1016/s0034-5288(96)90051-x
Nolan A, Reid J, Welsh E, Flaherty D, McCormack R, Monteiro AM.The pharmacokinetics of propofol and ketamine administered together by infusion were investigated in four ponies. Blood propofol and plasma ketamine and norketamine concentrations were measured by high performance liquid chromatography. After premedication with detomidine (20 micrograms kg-1) anaesthesia was induced with ketamine (2.2 mg kg-1 intravenously). The trachea was intubated and the ponies were allowed to breathe 100 per cent oxygen. A bolus dose of propofol (0.5 mg kg-1) was then administered intravenously and propofol and ketamine were infused for 60 and 45 minutes, respectively. Th...
Influence of chronic degenerative endometritis (endometrosis) on placental development in the mare.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 180-188 doi: 10.1111/j.2042-3306.1996.tb03771.x
Bracher V, Mathias S, Allen WR.Placentation between 80 and 220 days of gestation was studied by measurement of fetal dimensions and gross, light and transmission and scanning electron microscopic examinations of the allantochorion and endometrium from 4 fertile mares with no, or very mild, endometrial histopathology and 6 subfertile Thoroughbred mares suffering varying degrees of age-related chronic degenerative endometritis (endometrosis). Spontaneously occurring twin gestation was observed in 3 animals. Several of the subfertile mares had endometrial cysts which showed 2 distinct features during pregnancy: those located n...
Effects of administration of N-methyl-D,L-aspartate (NMA) on gonadotropin secretion in untreated and steroid-treated ovariectomized mares during the breeding season and in intact and ovariectomized mares during anestrus.
Domestic animal endocrinology    May 1, 1996   Volume 13, Issue 3 211-218 doi: 10.1016/0739-7240(96)00016-1
Fitzgerald BP.The purpose of this experiment was to investigate whether N-methyl-D,L-aspartate stimulated gonadotropin secretion in mares and to determine the response in two experimental paradigms where gonadotropin secretion is low or elevated. In Experiment 1, conducted during the breeding season (summer), eight long-term ovariectomized mares were treated daily for 21 d with progesterone plus estradiol (n = 4) or oil vehicle. Beginning on Day 14, each mare received, in a randomized design on alternate days, an intravenous injection of either 0, 0.5, 1.0, or 5.0 mg/kg NMA. Treatment with NMA was not accom...
Ultrasonographic assessment of fetal well-being during late gestation: development of an equine biophysical profile.
Equine veterinary journal    May 1, 1996   Volume 28, Issue 3 200-208 doi: 10.1111/j.2042-3306.1996.tb03773.x
Reef VB, Vaala WE, Worth LT, Sertich PL, Spencer PA.Mares with complicated pregnancies (illness, problems at parturition or delivery of an abnormal foal, n = 30) were scanned transabdominally from 298 days gestation to term in order to measure fetal size, evaluate fetal well-being and characterise the intrauterine environment. The results of the last scan obtained prior to parturition were compared to normal data obtained from fetuses of comparable gestational age to develop a biophysical profile specific for the equine fetus. Twelve mares produced a normal foal (positive outcome) and 18 mares delivered 19 abnormal foals (negative outcome). Bot...