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Topic:Lameness

Lameness in horses is a condition characterized by an abnormal gait or stance due to pain or mechanical dysfunction affecting the limbs or spine. It is a common issue in equine practice and can result from a variety of causes, including injury, infection, or degenerative diseases. Lameness can affect a horse's performance and quality of life, making accurate diagnosis and management important for equine health. Diagnostic techniques often include physical examination, imaging, and gait analysis. This page aggregates peer-reviewed research studies and scholarly articles that explore the etiology, diagnostic methods, and management strategies for lameness in horses.
Magnetic resonance imaging features of oblique and straight distal sesamoidean desmitis in 27 horses. Sampson SN, Schneider RK, Tucker RL, Gavin PR, Zubrod CJ, Ho CP.Injury to the oblique and straight distal sesamoidean ligaments is becoming recognized as a more common cause of lameness in horses than was previously thought. The purpose of this study was to review the magnetic resonance (MR) imaging findings of 27 horses affected with desmitis of the oblique and/or straight distal sesamoidean ligament and determine long-term prognosis for horses with this diagnosis. Imaging was performed with horses in right lateral recumbency in a high-field 1 T magnet. All horses had lameness localized to the digit or metacarpophalangeal/metatarsophalangeal joint region ...
Scintigraphic evaluation of the stifle in normal horses and horses with forelimb lameness. Dyson S, McNie K, Weekes J, Murray R.We tested the hypotheses that mature horses without lameness have a repeatable radiopharmaceutical uptake pattern in the stifle, which is bilaterally symmetric; immature horses have a different radiopharmaceutical uptake pattern; and forelimb lameness alters the radiopharmaceutical uptake pattern in the stifle. The objectives of the study were to describe the normal radiopharmaceutical uptake patterns using region of interest (ROI) analysis; to compare uptake patterns between left and right stifles of the same horse and between mature and immature horses; to compare radiopharmaceutical uptake ...
Veterinary-care events and costs over a 5-year follow-up period for warmblooded riding horses with or without previously recorded locomotor problems in Sweden.
Preventive veterinary medicine    August 6, 2007   Volume 83, Issue 2 130-143 doi: 10.1016/j.prevetmed.2007.06.008
Egenvall A, Bonnett B, Wattle O, Emanuelson U.Our objective was to determine the amount, type and cost of veterinary care during a 5-year follow-up period, in Swedish warmblooded riding horses with and without locomotor problems as recorded in 1997. The study population comprised horses with complete insurance both for veterinary care and life during 1997. The horses were followed from the beginning of January 1998 to the end of December 2002. The exposed cohort was composed of 1558 horses that had experienced >or=1 veterinary-care event because of locomotor problems in 1997 (LP-cohort). The exposure-negative (LN) cohort was composed o...
Fluorescence in situ hybridization analysis of hindgut bacteria associated with the development of equine laminitis.
Environmental microbiology    July 20, 2007   Volume 9, Issue 8 2090-2100 doi: 10.1111/j.1462-2920.2007.01327.x
Milinovich GJ, Trott DJ, Burrell PC, Croser EL, Al Jassim RA, Morton JM, van Eps AW, Pollitt CC.Carbohydrate-induced laminitis in horses is characterized by marked changes in the composition of the hindgut microbiota, from a predominantly Gram-negative population to one dominated by Gram-positive bacteria. The objective of this study was to monitor changes in the relative abundance of selected hindgut bacteria that have previously been implicated in the pathophysiology of equine laminitis using fluorescence in situ hybridization (FISH). Caecal cannulae were surgically implanted in five Standardbred horses and laminitis induced by oral administration of a bolus dose of oligofructose. Caec...
Evidence-based lameness detection and quantification.
The Veterinary clinics of North America. Equine practice    July 10, 2007   Volume 23, Issue 2 403-423 doi: 10.1016/j.cveq.2007.04.008
Keegan KG.Kinematic and kinetic gait analysis potentially offers veterinarians an objective method of determining equine limb lameness. Subjective analyses have been shown to be somewhat flawed, and there does not seem to be a high degree of intraobserver agreement when evaluating individual horses. In addition, recognition of the compensatory effects of primary lameness may be helpful for the practicing equine veterinarian.
Effects of intra-articular botulinum toxin type A in an equine model of acute synovitis: a pilot study.
American journal of physical medicine & rehabilitation    July 5, 2007   Volume 86, Issue 10 777-783 doi: 10.1097/PHM.0b013e3181157718
DePuy T, Howard R, Keegan K, Wilson D, Kramer J, Cook JL, Childers MK.To test the hypothesis that botulinum toxin type A (BoNT-A) can attenuate lameness associated with acute synovitis in an equine model. Methods: Four horses 2-6 yrs of age with clinically normal carpi were studied for 15 days. Kinematic gait analysis and clinical measures of lameness were conducted before and after experimental interventions. Horses were randomly assigned to either placebo (saline) or treatment (BoNT-A) groups. On day 0 of the intervention, 50 units of BoNT-A or an equivalent volume of saline (0.09%) was given into the middle carpal joints. On day 14, acute synovitis was induce...
Metacarpophalangeal collateral ligament reconstruction using small intestinal submucosa in an equine model.
Journal of biomedical materials research. Part A    July 4, 2007   Volume 84, Issue 1 219-229 doi: 10.1002/jbm.a.31432
Bertone AL, Goin S, Kamei SJ, Mattoon JS, Litsky AS, Weisbrode SE, Clarke RB, Plouhar PL, Kaeding CC.Xenogeneic porcine small intestinal submucosa (SIS) is a natural, biodegradable matrix that has been successfully used as a scaffold for repair of tissue defects. The goal of this study was to compare a collateral ligament transection surgically reconstructed with an anchored SIS ligament to a sham-operated control procedure for the correction of joint laxity using an equine model. Ten metacarpophalangeal joints from 10 horses had complete transection of the lateral collateral ligament. In 6 horses, the collateral ligament was reconstructed with a multilaminate strip of SIS anchored with screw...
Dietary fructan carbohydrate increases amine production in the equine large intestine: implications for pasture-associated laminitis.
Journal of animal science    June 25, 2007   Volume 85, Issue 11 2949-2958 doi: 10.2527/jas.2006-600
Crawford C, Sepulveda MF, Elliott J, Harris PA, Bailey SR.Pasture-induced laminitis in the horse is associated with the overconsumption of fermentable carbohydrate, in the form of simple sugars, fructans, or starch. The fermentation of carbohydrate in the cecum and large intestine results in the production of lactic acid and other toxins or "laminitis trigger factors." Vasoactive amines have been suggested as possible initiating factors. The aim of this study was to feed a commercially available form of fructan carbohydrate (inulin, 3 g/kg of BW per day) to normal ponies and to ponies predisposed to laminitis, to mimic a change from a basal hay diet ...
Virginiamycin and laminitis research.
The Veterinary record    June 19, 2007   Volume 160, Issue 24 852 doi: 10.1136/vr.160.24.852-a
Menzies-Gow N.No abstract available
Eosinophilic synovitis of the tarsocrural joint in a horse.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    June 5, 2007   Volume 20, Issue 2 142-145 doi: 10.1160/vcot-06-06-0053
Climent F, Carmona JU, Cuenca R, Prades M.Eosinophilic synovitis (ES) is a rare disease described in human and veterinary medicine. Only three cases have been reported in the horse. A case of tarsocrural synovitis in an Hispano-Arabian gelding is presented in this report. The patient presented with severe joint effusion and lameness of the right tarsocrural joint on admission. Synovial fluid analysis revealed an increased WBC of 12800 leukocytes/microliter with 76% of eosinophils. Lavage of the diseased joint and medical treatment with antibiotics and non-steroidal anti-inflammatory drugs produced remission of the clinical problem.
Upward fixation of the patella in the horse. A retrospective study.
Veterinary and comparative orthopaedics and traumatology : V.C.O.T    June 5, 2007   Volume 20, Issue 2 119-125 doi: 10.1160/vcot-06-01-0004
Dumoulin M, Pille F, Desmet P, Dewulf J, Steenhaut M, Gasthuys F, Martens A.The objective of the present study was to assess the incidence of upward fixation of the patella (UFP) in different types of patients and to evaluate the outcome of conservative and surgical treatment for correcting this condition. A particular attempt was made to find out whether corrective trimming and/or shoeing (CTS) is efficient in the conservative treatment of UFP, and whether a longer postoperative resting period reduces the risk of complications after medial patellar desmotomy (MPD). Medical records of 78 horses with intermittent or permanent UFP were analyzed retrospectively. Young an...
Septic osteitis of the distal phalanx in foals: 22 cases (1995-2002).
Journal of the American Veterinary Medical Association    June 5, 2007   Volume 230, Issue 11 1683-1690 doi: 10.2460/javma.230.11.1683
Neil KM, Axon JE, Todhunter PG, Adams PL, Caron JP, Adkins AR.To determine the clinical characteristics and outcome of foals with septic osteitis of the distal phalanx. Methods: Retrospective case series. Methods: 22 foals. Methods: Information obtained from medical records included signalment; clinical, laboratory, and radiographic findings; treatment method; and outcome. Foals included in the study had lameness referable to the foot, radiographic evidence of localized lysis or focal loss of bone density of the distal phalanx, and suppurative discharge or necrosis of the affected bone evident at surgery. Foals with a history or evidence of penetrating w...
Evaluation of avocado and soybean unsaponifiable extracts for treatment of horses with experimentally induced osteoarthritis.
American journal of veterinary research    June 5, 2007   Volume 68, Issue 6 598-604 doi: 10.2460/ajvr.68.6.598
Kawcak CE, Frisbie DD, McIlwraith CW, Werpy NM, Park RD.To evaluate the use of a combination of avocado and soybean unsaponifiable (ASU) extracts for the treatment of experimentally induced osteoarthritis in horses. Methods: 16 horses. Methods: Osteoarthritis was induced via osteochondral fragmentation in 1 middle carpal joint of each horse; the other joint underwent a sham operation. Horses were randomly allocated to receive oral treatment with ASU extracts (1:2 [avocado-to-soybean] ratio mixed in 6 mL of molasses; n = 8) or molasses (6 mL) alone (placebo treatment; 8) once daily from days 0 to 70. Lameness, response to joint flexion, synovial eff...
The effect of plain, eggbar and 6 degrees-wedge shoes on the distribution of pressure under the hoof of horses at the walk.
New Zealand veterinary journal    May 31, 2007   Volume 55, Issue 3 120-124 doi: 10.1080/00480169.2007.36753
Rogers CW, Back W.To quantify the effect of plain, wedged and eggbar shoes on the distribution of pressure under the hoof of horses at the walk, at selected areas of interest (AOI), to find scientific evidence for the perceived efficacy of these shoes in the treatment of palmar heel pain. Methods: Six clinically sound adult Warmblood mares weighing 551 (SD 25) kg were shod (forelegs) with either plain, eggbar or 6 degrees-wedge shoes using a latin-square experimental design. All horses were shod by the same farrier, and each balanced and aligned for its individual conformation. Data were collected on three walk...
The effect of induced forelimb lameness on thoracolumbar kinematics during treadmill locomotion.
Equine veterinary journal    May 25, 2007   Volume 39, Issue 3 197-201 doi: 10.2746/042516407x173668
Gómez Alvarez CB, Wennerstrand J, Bobbert MF, Lamers L, Johnston C, Back W, van Weeren PR.Lameness has often been suggested to result in altered movement of the back, but there are no detailed studies describing such a relationship in quantitative terms. Objective: To quantify the effect of induced subtle forelimb lameness on thoracolumbar kinematics in the horse. Methods: Kinematics of 6 riding horses was measured at walk and at trot on a treadmill before and after the induction of reversible forelimb lameness grade 2 (AAEP scale 1-5). Ground reaction forces (GRF) for individual limbs were calculated from kinematics. Results: The horses significantly unloaded the painful limb by 1...
Pharmacological effects of tiludronate in horses after long-term immobilization.
Bone    May 23, 2007   Volume 41, Issue 3 414-421 doi: 10.1016/j.bone.2007.05.005
Delguste C, Amory H, Doucet M, Piccot-Crézollet C, Thibaud D, Garnero P, Detilleux J, Lepage OM.Tiludronate, a bisphosphonate, has recently been introduced in veterinary medicine to treat orthopedic conditions in the horse. This study was designed to evaluate its effects on biochemical biomarkers of bone metabolism and on bone density and structure in an experimental model of disuse osteoporosis induced by cast application in horses. Methods: Two groups of eight horses were immobilized during 8 weeks. The first group (P-group) received a placebo, and the second group (T-group) received tiludronate 1 mg/kg by slow IV infusion. Both treatments were administered twice, 28 days apart. Immobi...
Validation of vertical ground reaction forces on individual limbs calculated from kinematics of horse locomotion.
The Journal of experimental biology    May 23, 2007   Volume 210, Issue Pt 11 1885-1896 doi: 10.1242/jeb.02774
Bobbert MF, Gómez Alvarez CB, van Weeren PR, Roepstorff L, Weishaupt MA.The purpose of this study was to determine whether individual limb forces could be calculated accurately from kinematics of trotting and walking horses. We collected kinematic data and measured vertical ground reaction forces on the individual limbs of seven Warmblood dressage horses, trotting at 3.4 m s(-1) and walking at 1.6 m s(-1) on a treadmill. First, using a segmental model, we calculated from kinematics the total ground reaction force vector and its moment arm relative to each of the hoofs. Second, for phases in which the body was supported by only two limbs, we calculated the individu...
Osteochondral fragments involving the dorsomedial aspect of the proximal interphalangeal joint in young horses: 6 cases (1997-2006).
Journal of the American Veterinary Medical Association    May 17, 2007   Volume 230, Issue 10 1498-1501 doi: 10.2460/javma.230.10.1498
Fjordbakk CT, Strand E, Milde AK, Ihler CF, Rorvik AM.To determine clinical and diagnostic imaging findings in young horses with osteochondral fragments involving the dorsomedial aspect of the proximal interphalangeal (PIP) joint. Methods: Retrospective case series. Methods: 6 horses. Methods: Medical records were reviewed. Follow-up information was obtained through telephone conversations with owners or trainers or by examining race records. Results: Horses were between 1 and 4 years old. Three had bilateral osteochondral fragments in the forelimbs (n = 2 horses) or hind limbs (1). Radiographically, all but 1 fragment seemed to originate from th...
Fractures of the greater tubercle of the humerus in horses: 15 cases (1986-2004).
Journal of the American Veterinary Medical Association    May 3, 2007   Volume 230, Issue 9 1350-1355 doi: 10.2460/javma.230.9.1350
Mez JC, Dabareiner RM, Cole RC, Watkins JP.To determine clinical and radiographic abnormalities in and outcome of horses with fractures of the greater tubercle of the humerus and to develop a radiographic technique for obtaining a cranioproximal-craniodistal oblique projection of the proximal portion of the humerus in standing horses. Methods: Retrospective case series. Methods: 15 horses. Methods: Data collected from medical records included signalment, history, horse use, severity and duration of lameness, radiographic and ultrasonographic findings, treatment, and outcome. Results: All horses had a history of acute, unilateral lamene...
Trot asymmetry in relation to physical performance and metabolism in equine endurance rides.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 50-54 doi: 10.1111/j.2042-3306.2006.tb05512.x
Muñoz A, Cuesta I, Riber C, Gata J, Trigo P, Castejón FM.Trot is a symmetric gait and asymmetry might appear or increase during endurance rides due to lameness, pain or excessive fatigue. Objective: To assess whether trot asymmetry increases during endurance competitions, whether it is possible to discriminate between horses with different performance and also its possible relationship with metabolism. Methods: Fifty-eight horses were filmed at trot during the lameness examinations in the vet-gates, before the competition (BCO), and after phases 1 (at 29 km), 2 (at 59 km) and 3 (at the end of the ride, at 80 km) and stride duration (SD) measured in ...
The effect of gallop training on hoof angle in thoroughbred racehorses.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 431-434 doi: 10.1111/j.2042-3306.2006.tb05582.x
Peel JA, Peel MB, Davies HM.The economic impact of soundness problems in racehorses is very high and low hoof angle at the toe has been associated with a lack of soundness. However, it is not clear what environmental and management factors might contribute to a low hoof angle. Objective: To investigate the hypothesis that the hooves of racehorses become flatter when in gallop training, as well as to determine factors contributing to this trend. Methods: Weekly hoof measurements were taken with a hoof gauge from 45 Thoroughbred racehorses; 4 Thoroughbred show horses kept in consistent conditions and shod by the same farri...
Changes in selected physiological and laboratory measurements in elite horses competing in a 160 km endurance ride.
Equine veterinary journal. Supplement    April 4, 2007   Issue 36 37-42 doi: 10.1111/j.2042-3306.2006.tb05510.x
Schott HC, Marlin DJ, Geor RJ, Holbrook TC, Deaton CM, Vincent T, Dacre K, Schroter RC, Jose-Cunilleras E, Cornelisse CJ.Limited information exists about the physiological changes and clinical problems that occur in elite horses competing in high-speed 160 km endurance races. Objective: To provide initial data describing changes in physiological and laboratory measurements in horses competing in a high-speed, 160 km endurance race under temperate conditions and to compare data between horses that successfully completed the race and those that failed to finish. Methods: Body mass (BM) was measured, blood samples were collected, and veterinary examinations performed on horses before, during, and at the finish of a...
Multivariable analysis of factors influencing outcome of 2 treatment protocols in 128 cases of horses responding positively to intra-articular analgesia of the distal interphalangeal joint.
Equine veterinary journal    March 24, 2007   Volume 39, Issue 2 150-156 doi: 10.2746/042516407x170094
Kristiansen KK, Kold SE.There is limited knowledge available of factors influencing response to treatments of the DIP-joint in horses with lameness responding to diagnostic analgesia of the DIP-joint. For this reason a multivariable statistical analysis was performed. Objective: Horses with lameness reduced by > or = 75% 10 min after intra-articular analgesia of the DIP-joint, can be treated successfully by intra-articular medication of the joint. Multiple factors influence the response to treatment. Methods: The study was performed retrospectively based on clinical records of horses treated with either polysulpha...
Risk factors for development of acute laminitis in horses during hospitalization: 73 cases (1997-2004).
Journal of the American Veterinary Medical Association    March 17, 2007   Volume 230, Issue 6 885-889 doi: 10.2460/javma.230.6.885
Parsons CS, Orsini JA, Krafty R, Capewell L, Boston R.To identify risk factors for development of acute laminitis in horses during hospitalization for illness or injury. Methods: Retrospective case-control study. Methods: 73 horses that developed laminitis (case horses) and 146 horses that did not develop laminitis (control horses) during hospitalization. Methods: Case and control horses were matched in a 2:1 ratio by the date on which each horse was evaluated. Potential risk factors investigated included age, breed, and sex; highest and lowest values recorded during hospitalization for fibrinogen concentration, WBC count, PCV, and total solids c...
Gluteal pyomyositis associated with septic proximal femoral physitis in a 12-day-old Standardbred filly foal.
Australian veterinary journal    March 16, 2007   Volume 84, Issue 10 371-374 doi: 10.1111/j.1751-0813.2006.00041.x
Hart JC, Smith C, Mogg TD.A 12-day-old Standardbred filly foal was presented with an acute onset hindlimb lameness of 24 hours duration. Initial ultrasonographic evaluation of the right gluteal region revealed oedematous change to the muscle architecture. Conservative therapy consisting of antimicrobials and stall rest was initiated. Forty-eight hours after admission a localised gluteal pyomyositis had developed. This was drained twice by percutaneous aspiration. Four days after admission the foal was euthanased. Necropsy examination revealed a septic proximal femoral physis with no grossly apparent joint involvement.
Clinical, biochemical, and histologic effects of intra-articular administration of autologous conditioned serum in horses with experimentally induced osteoarthritis.
American journal of veterinary research    March 3, 2007   Volume 68, Issue 3 290-296 doi: 10.2460/ajvr.68.3.290
Frisbie DD, Kawcak CE, Werpy NM, Park RD, McIlwraith CW.To assess the clinical, biochemical, and histologic effects of intra-articular administration of autologous conditioned serum (ACS) in the treatment of experimentally induced osteoarthritis in horses. Methods: 16 horses. Methods: Osteoarthritis was induced arthroscopically in 1 middle carpal joint of all horses. In 8 placebo- and 8 ACS-treated horses, 6 mL of PBS solution or 6 mL of ACS was injected into the osteoarthritis-affected joint on days 14, 21, 28, and 35, respectively; PBS solution was administered in the other sham-operated joints. Evaluations included clinical assessment of lamenes...
Intraarterial contrast-enhanced computed tomography of the equine distal extremity. Puchalski SM, Galuppo LD, Hornof WJ, Wisner ER.A technique for regional delivery of contrast medium to the foot of the horse to increase the diagnostic utility of computed tomography (CT) for the characterization of soft tissue structures within the hoof capsule was developed. An intraarterial catheter was placed under ultrasound guidance into the medial palmar artery at the level of the carpus to facilitate a steady-state infusion of iodinated contrast medium. Two 5 mm collimated contiguous acquisition CT scans were performed in 10 horses without lameness or radiographic evidence of distal sesamoid bone degeneration. CT examination was pe...
Scintigraphic evaluation of the proximal metacarpal and metatarsal regions of horses with proximal suspensory desmitis. Dyson SJ, Weekes JS, Murray RC.The aim of the study was to characterize radiopharmaceutical uptake patterns in horses with clinical and ultrasonographic evidence of proximal suspensory desmitis. It was hypothesized that radiopharmaceutical uptake in the proximal palmar (plantar) aspect of the third metacarpal (metatarsal) bone would be greater in lame limbs of horses with proximal suspensory desmitis than in sound limbs and that there would be a positive correlation between the severity of ultrasonographic abnormalities and the degree of radiopharmaceutical uptake. Nuclear scintigraphic evaluation of the proximal metacarpal...
The corticosteroid laminitis story: 2. Science of if, when and how.
Equine veterinary journal    January 19, 2007   Volume 39, Issue 1 7-11 doi: 10.2746/042516407x166035
Bailey SR, Elliott J.No abstract available
Hoof ground interaction: when biomechanical stimuli challenge the tissues of the distal limb.
Equine veterinary journal    January 19, 2007   Volume 38, Issue 7 634-641 doi: 10.2746/042516406x158341
Johnston C, Back W.No abstract available
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