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Topic:Musculoskeletal System

The musculoskeletal system in horses encompasses the bones, muscles, tendons, ligaments, and joints that facilitate movement and provide structural support. This system is essential for locomotion, athletic performance, and overall health in equine species. The equine skeleton consists of approximately 205 bones, which are connected by joints and supported by a network of muscles and connective tissues. Tendons connect muscles to bones, while ligaments link bones to other bones, contributing to joint stability. The musculoskeletal system is subject to various conditions, including injuries, degenerative diseases, and developmental disorders, which can impact a horse's mobility and performance. This page compiles peer-reviewed research studies and scholarly articles that explore the anatomy, physiology, pathology, and treatment of musculoskeletal conditions in horses.
Revisiting predictive biomarkers of musculoskeletal injury in thoroughbred racehorses: longitudinal study in polish population.
BMC veterinary research    February 26, 2019   Volume 15, Issue 1 66 doi: 10.1186/s12917-019-1799-7
Turlo AJ, Cywinska A, Frisbie DD.High prevalence of musculoskeletal disorders in racehorses and its impact on horse welfare and racing economics call for improved measures of injury diagnosis and prevention. Serum biomarkers of bone and cartilage metabolism have previously shown promise in prediction of musculoskeletal injuries in horses. This study aimed to re-evaluate usability of the predictive serum biomarkers identified in North American Thoroughbred racehorses in a geographically distinct group of Polish Thoroughbreds. Results: Serum concentrations of bone and cartilage biomarkers: osteocalcin, c-terminal telopeptide of...
Asymmetric recurrent laryngeal nerve conduction velocities and dorsal cricoarytenoid muscle electromyographic characteristics in clinically normal horses.
Scientific reports    February 25, 2019   Volume 9, Issue 1 2713 doi: 10.1038/s41598-019-39189-z
Cercone M, Hokanson CM, Olsen E, Ducharme NG, Mitchell LM, Piercy RJ, Cheetham J.The dorsal cricoarytenoid (DCA) muscles, are a fundamental component of the athletic horse's respiratory system: as the sole abductors of the airways, they maintain the size of the rima glottis which is essential for enabling maximal air intake during intense exercise. Dysfunction of the DCA muscle leads to arytenoid collapse during exercise, resulting in poor performance. An electrodiagnostic study including electromyography of the dorsal cricoarytenoid muscles and conduction velocity testing of the innervating recurrent laryngeal nerves (RLn) was conducted in horses with normal laryngeal fu...
Chondrogenic differentiation potential of adult and fetal equine cell types.
Veterinary surgery : VS    February 25, 2019   Volume 48, Issue 3 375-387 doi: 10.1111/vsu.13183
Adam EN, Janes J, Lowney R, Lambert J, Thampi P, Stromberg A, MacLeod JN.To determine the chondrogenic potential of cells derived from interzone tissue, the normal progenitor of articular cartilage during fetal development, compared to that of adult bone marrow-derived and adipose-derived mesenchymal cell isolates. The objective of this study was to compare the chondrogenic potential of fetal musculoskeletal progenitor cells to adult cell types, which are currently used therapeutically to facilitate joint cartilage repair in equine clinical practice. The hypothesis tested was that cells derived from interzone tissue have a chondrogenic potential that exceeds that o...
Enhanced ultrasonographic imaging of the equine distal limb using saline injection of the digital flexor tendon sheath: A cadaver study.
Veterinary journal (London, England : 1997)    February 23, 2019   Volume 247 26-31 doi: 10.1016/j.tvjl.2019.02.007
Daniel AJ, Leise BS, Selberg KT, Barrett MF.Injuries to the structures within the digital flexor tendon sheath (DFTS) can lead to lameness with a variable degree of effusion in horses. In some cases, effusion is absent or minimal, and this may be related to the chronicity and type of injury, or veterinary interventions. The purpose of this study was to determine if saline injection into the DFTS would improve ultrasonographic and magnetic resonance imaging of the distal limb without introducing artifact. Nine normal equine cadaver forelimbs were collected. Non-weight-bearing ultrasonographic and magnetic resonance imaging (MRI) examinat...
Influence of mechanical fluid shear stress on the osteogenic differentiation protocols for Equine adipose tissue-derived mesenchymal stem cells.
Acta histochemica    February 23, 2019   Volume 121, Issue 3 344-353 doi: 10.1016/j.acthis.2019.02.002
Elashry MI, Gegnaw ST, Klymiuk MC, Wenisch S, Arnhold S.Cell-based therapies have become a promising approach to promote tissue regeneration and the treatment of musculoskeletal disorders. Bone regeneration maintains bone homeostasis, mechanical stability and physical performance. Mechanical stimulation showed to induce stem cell differentiation into the osteogenic fate. However, the effect of various osteogenic protocols on the osteogenic commitment of equine adipose-derived stem cells is not fully elucidated. Here we examined the influence of fluid-based shear stress (FSS) via mechanical rocking to assess whether mechanical stimulation promotes o...
Heritability estimates of fractures in Japanese Thoroughbred racehorses using a non-linear model.
Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie    February 21, 2019   Volume 136, Issue 3 199-204 doi: 10.1111/jbg.12387
Tozaki T, Miyake T, Kikuchi M, Kakoi H, Hirota KI, Kusano K, Ishikawa Y, Nomura M, Kushiro A, Nagata SI.Thoroughbred racehorses are produced by mating small numbers of Arabian stallions and native British mares, and have been improved by selection of horseracing performance for about 300 years. While these improvements led to good performance as racehorses, they exposed horses to numerous medical disorders, aggravated by extensive exercise. Fractures are frequent medical disorders in Thoroughbred racehorses. In this study, fracture heritability was estimated using 3,927 Japanese Thoroughbred racehorses to elucidate the risk of racehorse fractures. The heritability estimates of all examined frac...
The Influence of Body Mass and Height on Equine Hoof Conformation and Symmetry.
Journal of equine veterinary science    February 21, 2019   Volume 77 43-49 doi: 10.1016/j.jevs.2019.02.013
Leśniak K, Whittington L, Mapletoft S, Mitchell J, Hancox K, Draper S, Williams J.Despite the likelihood that a horse's mass influences hoof morphology, empirical evidence is lacking. A clearer understanding of factors influencing hoof shape could enable prevention, or better treatment, of foot-based disorders; common causes of equine lameness. The study's aim was to investigate the relationship between horse body size, in terms of mass and height, and fore hoof dimensions. A further aim was to determine changes in the occurrence of hoof asymmetry as body size increases. Height, mass, and fore hoof dimensions; coronet band width (CBW); hoof base width (HBW); dorsal hoof wal...
Musculoskeletal problems associated with lameness and poor performance in cutting horses: 200 cases (2007-2015).
Journal of the American Veterinary Medical Association    February 20, 2019   Volume 254, Issue 5 619-625 doi: 10.2460/javma.254.5.619
Swor TM, Dabareiner RM, Honnas CM, Cohen ND, Black JB.OBJECTIVE To describe the chief complaints by owners and the types and prevalences of musculoskeletal problems associated with lameness or poor performance in cutting horses. DESIGN Retrospective case series. ANIMALS 200 client-owned cutting horses examined at the Texas A&M University Veterinary Medical Teaching Hospital between January 1, 2007, and December 31, 2015, because of lameness or poor performance. PROCEDURES Medical records were reviewed, and data were collected regarding signalment, history, findings on physical and lameness examinations, results of diagnostic procedures performed,...
Fragmentation of the dorsal distal aspect of the talus on weanling survey and pre-sale radiographs of juvenile Thoroughbreds: prevalence and 2- and 3-year-olds racing performance.
Australian veterinary journal    February 17, 2019   Volume 97, Issue 3 68-74 doi: 10.1111/avj.12787
Steel CM, Devery S, Hance SR, Adkins AR, Hitchens PL.Fragmentation of the dorsal aspect of the distal talus (FDDT), at the dorsolateral articular margin of the proximal intertarsal joint (PITJ) on pre-sale radiographs of yearling Thoroughbreds has not been previously described and data to support decisions made by veterinarians to predict future racing potential of horses with these lesions are lacking. Methods: In this retrospective case-control study we aimed to determine the prevalence of FDDT in juvenile Thoroughbreds and to report their race records. From a database of survey and repository radiographic examinations of 5709 horses, 36 with ...
Balance control during stance – A comparison between horseback riding athletes and non-athletes.
PloS one    February 5, 2019   Volume 14, Issue 2 e0211834 doi: 10.1371/journal.pone.0211834
Olivier A, Viseu JP, Vignais N, Vuillerme N.Horseback riding requires the ability to adapt to changes in balance conditions, to maintain equilibrium on the horse and to prevent falls. Postural adaptation involves specific sensorimotor processes integrating visual information and somesthesic information. The objective of this study was to examine this multisensorial integration on postural control, especially the use of visual and plantar information in static (stable) and dynamic (unstable) postures, among a group of expert horse rider women (n = 10) and a group of non-athlete women (n = 12). Postural control was evaluated through the c...
Using Movement Sensors to Assess Lying Time in Horses With and Without Angular Limb Deformities.
Journal of equine veterinary science    January 31, 2019   Volume 75 55-59 doi: 10.1016/j.jevs.2019.01.011
Clothier J, Small A, Hinch G, Barwick J, Brown WY.Chronic musculoskeletal pathologies are common in horses, however, identifying related effects can be challenging. This study tested the hypothesis that movement sensors and analgesics could be used in combination to confirm the presence of restrictive pathologies by assessing lying time. Four horses presenting a range of angular limb deformities (ALDs) and four nonaffected controls were used. The study comprised two trials at separate paddock locations. Trial A consisted of a 3-day baseline phase and 2 × 3-day treatment phases, during which two analgesics were administered to two ALD horses...
Three-dimensional CT observation of position and movability of the scapula in the horse using carcasses of Falabella.
Anatomia, histologia, embryologia    January 29, 2019   Volume 48, Issue 3 250-255 doi: 10.1111/ahe.12430
Endo H, Nguyen ST, Yoshida M, Kudo K.The three-dimensionally real position and movement of the scapula in the lateral side of the ribcage could not be clarified in the horse, since the body size of the horse is too large to apply the CT scanning and image analysis methods. In this study, therefore, we examined the position and the movability of scapula using a carcass of the Falabella which is one of the smallest breeds of the horse. The whole skeletal system in thoracic part of the Falabella could be three-dimensionally observed by CT scanning method. The three-dimensional images show that the scapula cranially slides and the ve...
Low field magnetic resonance imaging of the equine distal interphalangeal joint: Comparison between weight-bearing and non-weight-bearing conditions.
PloS one    January 28, 2019   Volume 14, Issue 1 e0211101 doi: 10.1371/journal.pone.0211101
Evrard L, Audigié F, Bertoni L, Jacquet S, Denoix JM, Busoni V.This descriptive study aimed to compare the magnetic resonance appearance of the distal interphalangeal joint articular cartilage between standing weight-bearing and non-weight-bearing conditions. Ten forefeet of live horses were scanned in a standing low-field magnetic resonance system (0.27 T). After euthanasia for reasons unrelated to the study, the non-weight-bearing isolated feet were scanned in a vertical positioning reproducing limb orientation in live horses. The same acquisition settings as during the weight-bearing examination were used. Thickness and cross-sectional area of the dist...
The Effect of Core Abdominal Muscle Rehabilitation Exercises on Return to Training and Performance in Horses After Colic Surgery.
Journal of equine veterinary science    January 25, 2019   Volume 75 14-18 doi: 10.1016/j.jevs.2019.01.001
Holcombe SJ, Shearer TR, Valberg SJ.We conducted a retrospective cohort study to test the hypothesis that performing 4 weeks of core abdominal rehabilitation exercises (CARE) postoperatively would be safe and associated with faster return to training and improved performance after colic surgery. Performance horses that recovered from colic surgery performed by the same surgeon and survived ≥ 1 year from 2008 to 2017 were included. Data were obtained from a review of medical records. Information about the horses' rehabilitation and performance was obtained from owners/trainers. Data from horses that completed a 4-week CARE pr...
Reliability of equine visual lameness classification.
The Veterinary record    January 13, 2019   Volume 184, Issue 2 60-62 doi: 10.1136/vr.k5366
Keegan KG.No abstract available
Correction: Effects of intrabursal administration of botulinum toxin type B on lameness in horses with degenerative injury to the podotrochlear apparatus.
American journal of veterinary research    January 4, 2019   Volume 80, Issue 1 78 doi: 10.2460/ajvr.80.1.78
No abstract available
Evaluation of standing low-field magnetic resonance imaging for diagnosis of advanced distal interphalangeal primary degenerative joint disease in horses: 12 cases (2010-2014).
Journal of the American Veterinary Medical Association    January 4, 2019   Volume 254, Issue 2 257-265 doi: 10.2460/javma.254.2.257
Rovel T, Audigié F, Coudry V, Jacquet-Guibon S, Bertoni L, Denoix JM.OBJECTIVE To report history, findings from clinical examinations and diagnostic imaging, treatment, and outcomes associated with distal interphalangeal primary degenerative joint disease (DIP-PDJD) and to evaluate diagnostic usefulness and limitations of standing low-field MRI, relative to radiography and ultrasonography, for the diagnosis of DIP-PDJD in horses. DESIGN Retrospective case series with nested evaluation study. ANIMALS 12 client-owned horses. PROCEDURES Medical records were reviewed, and data were collected regarding signalment, history, results of physical and diagnostic imaging ...
The reliability and forensic soundness of the equine shin circumference measurement in living animals versus post‑mortem examination.
Veterinaria italiana    December 31, 2018   Volume 54, Issue 4 281-286 doi: 10.12834/VetIt.1497.8069.2
Peli A, Roccaro M.Catastrophic injuries in racehorses mostly involve the metacarpal region. Although many studies describe fractures of equine limbs, few examine the relationship between bone morphometrics and musculoskeletal problems in racing horses. And yet, according to the regulation of some Italian traditional races, the shin circumference represents a qualifying prerequisite for horses to be admitted to races. This study aims to evaluate the conformity of the shin circumference measurement in living animals and in post‑mortem examinations, in order to evaluate the forensic reliability of these measurem...
Letter to the Editor: A response to ‘What is lameness and what (or who) is the gold standard to detect it?’.
Equine veterinary journal    December 20, 2018   Volume 51, Issue 2 270-272 doi: 10.1111/evj.13043
Adair S, Baus M, Bell R, Boero M, Bussy C, Cardenas F, Casey T, Castro J, Davis W, Erskine M, Farr R, Fischer A, Forbes B, Ford T, Genovese R....No abstract available
The expression profile of genes involved in osteoclastogenesis detected in whole blood of Arabian horses during 3 years of competing at race track.
Research in veterinary science    December 18, 2018   Volume 123 59-64 doi: 10.1016/j.rvsc.2018.12.013
Stefaniuk-Szmukier M, Ropka-Molik K, Piórkowska K, Bugno-Poniewierska M.One of the most significant reason of economic loss on race track performance is lame in performed horses. Primarily, due to the failure within proper bone maintenance during conditioning in young horses. The training overload causes bone turnover disturbances in homeostasis between bone resorption and bone formation which promote the bone loss. Within our study we investigated training induced changes in transcript abundance of genes (NFATc1, CTSK, DAP12, CLEC5A, IL6ST, VAV3) involved in osteoclastogenesis hence bone resorption, in whole blood of Arabian horses. The expression pattern of all ...
Impact of a void in the equine medial femoral condyle on bone stresses and peak contact pressures in a finite element model.
Veterinary surgery : VS    December 16, 2018   Volume 48, Issue 2 237-246 doi: 10.1111/vsu.13139
Frazer LL, Santschi EM, Fischer KJ.To predict bone and medial meniscal stresses and contact pressures in an equine stifle with a medial femoral condyle (MFC) intact or with a 2-cm subchondral bone void, under varying degrees of internal femoral rotation (IFR). Methods: Finite element model (FEM) of a cadaveric equine stifle loaded to 8000 N. Methods: The FEM was constructed from computed tomography (CT) of the right, extended stifle of a yearling. The CT image was segmented into relevant anatomic structures and meshed into 4-node tetrahedrons. Bone material properties were assigned according to Hounsfield units, soft tissue p...
Histological examination of the interspinous ligament in horses with overriding spinous processes.
Veterinary journal (London, England : 1997)    December 12, 2018   Volume 244 69-74 doi: 10.1016/j.tvjl.2018.12.012
Ehrle A, Ressel L, Ricci E, Merle R, Singer ER.The equine interspinous ligament (ISL) consists of an oblique crossing arrangement of collagenous bundles which are thought to counteract the tensile and rotational forces of distraction between the spinous processes (SPs) in the caudal thoracic and cranial lumbar spine. The aim of this controlled histological study was to assess the structural anatomy and innervation of the ISL in horses with clinically significant overriding (dorsal) SPs (ORSPs) and to compare the findings with the ISL of normal horses. Samples of the ISL were obtained from 10 horses that underwent subtotal ostectomy for tre...
Neuromyotonia in a horse.
Journal of veterinary internal medicine    December 3, 2018   Volume 33, Issue 1 287-291 doi: 10.1111/jvim.15353
Zakia LS, Palumbo MIP, Teixeira RBC, Resende LAL, Soares MP, de Oliveira-Filho JP, Amorim RM, Borges AS.This article describes the clinical and electromyographic findings of neuromyotonia in a 19-month-old male crossbred Quarter Horse that presented with stiffness and muscle asymmetry in the hind limbs as well as sacrococcygeal, paravertebral, and gluteal myokymia. An electromyographic study showed spontaneous continuous muscle fiber activity with high-frequency discharges, fibrillations, positive sharp waves, fasciculation potentials, and complex repetitive discharges. Histological examination of the gluteal muscle showed a mixed neurogenic and myopathic pattern. The findings are consistent wit...
Simultaneous miRNA and mRNA Transcriptome Profiling of Differentiating Equine Satellite Cells Treated with Gamma-Oryzanol and Exposed to Hydrogen Peroxide.
Nutrients    December 2, 2018   Volume 10, Issue 12 1871 doi: 10.3390/nu10121871
Chodkowska KA, Ciecierska A, Majchrzak K, Ostaszewski P, Sadkowski T.Gamma-oryzanol (GO) is a popular supplement for performance horses, dogs, and humans. Previous studies indicated that GO supplementation decreases creatine kinase activity and lactate level after exercise and may affect oxidative stress in Thoroughbred horses. GO may change genes expression in equine satellite cells (ESC). The purpose of this study was to evaluate the effect of GO on miRNA, gene expression, oxidative stress, and cell damage and viability in differentiating ESC pretreated with hydrogen peroxide (H₂O₂). ESCs were obtained from a young horse's skeletal muscle. ESCs were pre-i...
Clinical insights: Biomechanics and lameness diagnosis.
Equine veterinary journal    December 1, 2018   Volume 51, Issue 1 5-6 doi: 10.1111/evj.13036
Gómez Álvarez CB.No abstract available
Meta-analysis of risk factors for racehorse catastrophic musculoskeletal injury in flat racing.
Veterinary journal (London, England : 1997)    December 1, 2018   Volume 245 29-40 doi: 10.1016/j.tvjl.2018.11.014
Hitchens PL, Morrice-West AV, Stevenson MA, Whitton RC.Studies of racehorse injury or fatality in various countries have identified common, and in some cases conflicting, risk factors. We conducted a systematic search of the relevant literature published from 1990 to 2017. Peer-reviewed articles were included if they reported the incidence of fatal or catastrophic musculoskeletal injury (CMI) in Thoroughbred flat races (n=21) or risk factors for CMI (n=65). Pooled effect sizes were estimated using the random-effects DerSimonian-Laird model. The pooled incidence of CMI was 1.17 (95% confidence interval 0.90, 1.44) per 1000 race starts. Almost 300 f...
Track Surfaces Used for Ridden Workouts and Alternatives to Ridden Exercise for Thoroughbred Horses in Race Training.
Animals : an open access journal from MDPI    November 26, 2018   Volume 8, Issue 12 221 doi: 10.3390/ani8120221
Morrice-West AV, Hitchens PL, Walmsley EA, Whitton RC.Little is known about the types of surfaces used during training of Thoroughbred racehorses or methods of exercise used in addition to ridden track-work. Our aims were to (1) describe the types of surfaces used in the training of Thoroughbred racehorses and to (2) identify alternative approaches used to exercise horses in addition to, or in place of, ridden overground track-work. Information regarding surface and alternative exercise methods was collected as part of an in-person survey of training practices of 66 registered Thoroughbred trainers in Victoria, Australia. Sand and synthetic surfa...
The Use of Bone Marrow Concentrate in the Treatment of Full-Thickness Chondral Defects.
HSS journal : the musculoskeletal journal of Hospital for Special Surgery    November 26, 2018   Volume 15, Issue 1 96-99 doi: 10.1007/s11420-018-9647-z
Apostolakos JM, Lazaro L, Williams RJ.This article is a critical analysis of a study, "Minimally Manipulated Bone Marrow Concentrate Compared with Microfracture Treatment of Full-Thickness Chondral Defects: A One-Year Study in an Equine Model," by Chu et al. (. 100(2):138-146, 2018). The investigation compared two interventions in the management of full-thickness chondral defects in an equine model: autologous bone marrow concentrate without concomitant microfracture treatment versus microfracture treatment alone. This review analyzes the methodology and results of their investigation and examines how their findings may influence ...
Bone marrow lesions of the distal condyles of the third metacarpal bone are common and not always related to lameness in sports and pleasure horses. De Guio C, Ségard-Weisse E, Thomas-Cancian A, Schramme M.The metacarpophalangeal joint is a common site of pain in horses. Little information is available about bone marrow lesions in the distal condyles of the third metacarpal bone in sports and pleasure horses. Aims of this prospective, retrospective, observational study were to evaluate the prevalence of bone marrow lesions in the distal condyles of the third metacarpal bone, to describe their anatomic distribution and to correlate lesions with the presence of lameness and the level and type of activity. All sports and pleasure horses undergoing standing low-field MRI of the front fetlock region ...
In vitro mechanical evaluation of three transfixation pin-cast constructs applied to equine forelimbs.
American journal of veterinary research    November 21, 2018   Volume 79, Issue 12 1287-1297 doi: 10.2460/ajvr.79.12.1287
Thomas KL, Carmalt JL, Burnett WD, Arjmand H, Johnston JD.OBJECTIVE To compare strain at the bone-pin and cast-pin interfaces among 3 transfixation pin-cast constructs applied to equine forelimbs. ANIMALS 15 forelimbs from 15 adult horses. PROCEDURES Limbs were randomly assigned to 1 of 3 constructs. Centrally threaded positive-profile pins were used for all constructs, and the most distal pin was placed just proximal to the epicondyles of the third metacarpal bone. Construct 1 consisted of two 6.3-mm-diameter pins spaced 4 cm apart at 30° to each other. Construct 2 was the same as construct 1 except the pins were placed 5 cm apart. Construct 3 cons...
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